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Items 1 to 31 of about 31
1. Nakagawa T, Hiraoka N, Ihara F, Komiyama M, Kanai Y, Matsuno Y: Primary adenocarcinoma of the rete testis with preceding diagnosis of pulmonary metastases. Int J Urol; 2006 Dec;13(12):1532-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary adenocarcinoma of the rete testis with preceding diagnosis of pulmonary metastases.
  • We report a case of primary adenocarcinoma of the rete testis in a 55-year-old man with pulmonary metastases that were detected 11 months prior to the diagnosis of the primary lesion.
  • Primary adenocarcinoma of the rete testis is an extremely rare malignant tumor with a poor outcome.
  • The diagnosis is often delayed because of non-specific clinical presentation and symptoms.
  • We cannot forget that rete testis is a possible primary site for a primary, unknown metastatic adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Lung Neoplasms / secondary. Rete Testis / pathology. Testicular Neoplasms / pathology

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  • (PMID = 17118031.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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2. Baydar DE, Kosemehmetoglu K, Akdogan B, Ozen H: Prostatic adenosquamous carcinoma metastasizing to testis. ScientificWorldJournal; 2006;6:2491-4
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  • [Title] Prostatic adenosquamous carcinoma metastasizing to testis.
  • Most arise after hormonal or radiotherapy of conventional prostatic adenocarcinoma.
  • Here, we present a unique case of "de novo prostatic adenosquamous carcinoma with focal sarcomatoid areas" that showed testicular metastasis, detected after scrotal orchiectomy.
  • [MeSH-major] Carcinoma, Adenosquamous / diagnosis. Carcinoma, Adenosquamous / pathology. Prostatic Neoplasms / diagnosis. Prostatic Neoplasms / pathology. Testicular Neoplasms / secondary
  • [MeSH-minor] Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Metastasis. Prostate / pathology. Prostate-Specific Antigen / biosynthesis. Testis / pathology. Treatment Outcome

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  • (PMID = 17619723.001).
  • [ISSN] 1537-744X
  • [Journal-full-title] TheScientificWorldJournal
  • [ISO-abbreviation] ScientificWorldJournal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] EC 3.4.21.77 / Prostate-Specific Antigen
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3. Haupt B, Ro JY, Ayala AG, Zhai J: Metastatic prostatic carcinoma to testis: histological features mimicking lymphoma. Int J Clin Exp Pathol; 2009;2(1):104-7
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  • [Title] Metastatic prostatic carcinoma to testis: histological features mimicking lymphoma.
  • We report a case of prostatic carcinoma with testicular metastasis, which mimicked malignant lymphoma of the testis.
  • The patient was a 71 year-old man with a history of prostate adenocarcinoma of Gleason score 9 (4+5) diagnosed in 2001 for which he received hormonal therapy.
  • However, immunohistochemical stains were positive for prostate-specific antigen and prostate acid phosphatase and negative for leukocyte common antigen, which confirmed the diagnosis of metastatic prostate adenocarcinoma.

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  • [Cites] CA Cancer J Clin. 2006 Mar-Apr;56(2):106-30 [16514137.001]
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  • (PMID = 18830384.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; lymphoma / metastasis / prostate cancer / testis
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4. Menon S, Gujral S, Bakshi G, Tongaonkar HB: Bilateral testicular metastasis from prostatic adenocarcinoma mimicking an intertubular pattern of seminoma and expressing Rhamm. J Cancer Res Ther; 2010 Jan-Mar;6(1):97-9
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  • [Title] Bilateral testicular metastasis from prostatic adenocarcinoma mimicking an intertubular pattern of seminoma and expressing Rhamm.
  • Adenocarcinoma of prostate metastasizing to testis is a rare occurrence and is incidentally detected in orchiectomy specimens.
  • The pattern of metastasis may mimic a primary neoplasm of testis like a seminoma or lymphoma and pose a diagnostic difficulty for the pathologist.
  • A rare case of bilateral testicular metastasis of prostatic adenocarcinoma is presented wherein the metastatic cells expressed CD168, a receptor for hyaluronan mediated motility (Rhamm), implicated in the development of androgen independence in prostate cancer.
  • [MeSH-major] Adenocarcinoma / secondary. Antigens, CD44 / biosynthesis. Extracellular Matrix Proteins / biosynthesis. Prostatic Neoplasms / pathology. Seminoma / pathology. Testicular Neoplasms / secondary
  • [MeSH-minor] Antineoplastic Agents, Hormonal / therapeutic use. Bone Neoplasms / secondary. Combined Modality Therapy. Diagnosis, Differential. Humans. Leuprolide / therapeutic use. Male. Middle Aged. Orchiectomy. Ultrasound, High-Intensity Focused, Transrectal

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  • (PMID = 20479558.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Antineoplastic Agents, Hormonal; 0 / Extracellular Matrix Proteins; 0 / hyaluronan-mediated motility receptor; EFY6W0M8TG / Leuprolide
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5. Bauduceau O, Vedrine L, Chargari C, Ceccaldi B, Le Moulec S, Houlgatte A: [Testicular metastasis of prostatic adenocarcinoma: a case report]. Prog Urol; 2007 Apr;17(2):251-2
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  • [Title] [Testicular metastasis of prostatic adenocarcinoma: a case report].
  • Metastasis of prostate adenocarcinoma to testis is an extremely rare occurrence.
  • Orchiectomy is necessary to confirm histopathological diagnosis.
  • Metastatic carcinoma of the prostate to the testis is a commonly accepted as a sign of disseminated disease.
  • We report a case of a 62-year-old patient who presented a prostatic carcinoma with a testicular metastasis.
  • [MeSH-major] Adenocarcinoma / secondary. Prostatic Neoplasms / pathology. Testicular Neoplasms / secondary

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  • (PMID = 17489329.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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6. Amin MB: Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors. Mod Pathol; 2005 Feb;18 Suppl 2:S131-45
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  • [Title] Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors.
  • The proximity and, in some instances, communication between several structures in the testis and paratestis (rete testis, epididymis, mesothelium, vestigial epithelium and paratesticular soft tissue) result in a plethora of interesting tumors and tumor-like lesions that together pose a formidable diagnostic challenge both because of their morphologic overlap and rarity.
  • This review provides an overview of the pathology of nonmesenchymal paratesticular neoplasms and pseudotumors with a focus on the approach to tubulopapillary neoplasms for which diagnostic considerations may include carcinoma of the rete testis, malignant mesothelioma, ovarian-type epithelial tumors, epididymal carcinoma and metastatic carcinomas.
  • [MeSH-major] Testicular Neoplasms / pathology. Testis / pathology
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenomatoid Tumor / metabolism. Adenomatoid Tumor / pathology. Algorithms. Biomarkers, Tumor / analysis. Cystadenocarcinoma, Papillary / metabolism. Cystadenocarcinoma, Papillary / pathology. Cystadenocarcinoma, Serous / metabolism. Cystadenocarcinoma, Serous / pathology. Diagnosis, Differential. Epithelium / chemistry. Epithelium / pathology. Humans. Hyperplasia. Immunohistochemistry. Male. Mesothelioma / metabolism. Mesothelioma / pathology. Rete Testis / chemistry. Rete Testis / pathology

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  • (PMID = 15502808.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 48
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7. Yang KC, Chao Y, Luo JC, Kuo JY, Lee RC, Li AF, Li CP: The unusual presentation of gastric adenocarcinoma as a testicular mass: a favorable response to docetaxel and Cisplatin plus oral tegafur/uracil and leucovorin. J Chin Med Assoc; 2010 Feb;73(2):88-92
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  • [Title] The unusual presentation of gastric adenocarcinoma as a testicular mass: a favorable response to docetaxel and Cisplatin plus oral tegafur/uracil and leucovorin.
  • Testicular metastasis is rare.
  • We present here a 23-year-old gastric cancer patient who first presented with right-side testis swelling and pain.
  • Diagnosis of metastatic adenocarcinoma was made after right-side orchiectomy.
  • Gastric adenocarcinoma with ascites and peritoneal seeding was found after esophagogastroscopy and abdominal computed tomography.
  • Metastatic tumors, especially gastric adenocarcinoma, should be considered in the differential diagnosis of patients presenting with testicular mass and they may respond well to chemotherapy.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Stomach Neoplasms / drug therapy. Testicular Neoplasms / secondary

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  • [Copyright] Copyright 2010 Elsevier. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20171588.001).
  • [ISSN] 1728-7731
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Chemical-registry-number] 0 / Taxoids; 1548R74NSZ / Tegafur; 15H5577CQD / docetaxel; 56HH86ZVCT / Uracil; Q20Q21Q62J / Cisplatin; Q573I9DVLP / Leucovorin
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8. Okada T, Akada M, Fujita T, Iwata T, Goto Y, Kido K, Okada T, Matsuzaki Y, Kobayashi K, Matsuno S, Sunamura M, Kawakami Y: A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers. Clin Cancer Res; 2006 Jan 1;12(1):191-7
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  • [Title] A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers.
  • PURPOSE: To isolate cancer testis antigens that are expressed in pancreatic cancers and may be useful in clinical applications.
  • EXPERIMENTAL DESIGN: To efficiently isolate cancer testis antigens, a testis cDNA library was immunoscreened (SEREX) with serum from a patient with pancreatic ductal adenocarcinoma.
  • RESULTS: Of the three clones isolated through screening of a total of 2 x 10(6) cDNA library clones, one clone (KU-CT-1) was found to be expressed in various cancers but only in testis among normal tissues, indicating that it was a novel cancer testis antigen.
  • CONCLUSIONS: KU-CT-1 is a new cancer testis antigen that is expressed in pancreatic, lung, and endometrial cancers and may be useful for diagnosis and immunotherapy for patients with various cancers.
  • [MeSH-minor] Amino Acid Sequence. Base Sequence. Blotting, Northern. Cell Line, Tumor. Endometrial Neoplasms / genetics. Female. Humans. Lung Neoplasms / genetics. Male. Molecular Sequence Data. Pancreatic Neoplasms / genetics. Reverse Transcriptase Polymerase Chain Reaction. Testis / physiology

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  • (PMID = 16397042.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neoplasm Proteins
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9. Rubegni P, Poggiali S, De Santi M, Marsili S, Bilenchi R, Miracco C, Fimiani M: Cutaneous metastases from adenocarcinoma of the rete testis. J Cutan Pathol; 2006 Feb;33(2):181-4
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  • [Title] Cutaneous metastases from adenocarcinoma of the rete testis.
  • Adenocarcinoma of the rete testis (ACRT) is extremely rare and has only been the subject of sporadic case reports, in most of which the neoplasm manifested as a scrotal mass with diffuse enlargement of the testis.
  • The diagnosis was based on clinical and histopathological findings and supported by the results of immunohistochemical and ultrastructural studies.
  • We discuss the differential diagnosis to this rare entity, which include metastatic adenocarcinoma, serous tumor of the testis, and mesothelioma of the tunica vaginalis.
  • [MeSH-major] Adenocarcinoma / secondary. Rete Testis / pathology. Skin Neoplasms / secondary. Testicular Neoplasms / pathology

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  • (PMID = 16420316.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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10. Sogni F, Monga G, Terrone C, Gontero P: Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. Scand J Urol Nephrol; 2008;42(1):83-5
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  • [Title] Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas.
  • We describe a rare case of a malignant tumour of the rete testis which was diagnosed incidentally during scrotal surgery for an apparently benign left hydrocele.
  • Adenocarcinoma of the rete testis is a malignancy with a poor prognosis.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Testicular Neoplasms / diagnosis. Testicular Neoplasms / surgery
  • [MeSH-minor] Aged. Humans. Incidental Findings. Male. Testicular Hydrocele / surgery

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  • (PMID = 17853037.001).
  • [ISSN] 0036-5599
  • [Journal-full-title] Scandinavian journal of urology and nephrology
  • [ISO-abbreviation] Scand. J. Urol. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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11. Hagiuda J, Matsumoto M, Hanawa Y, Ishikawa H, Marumo K: [Adenocarcinoma of the rete testis. A case report]. Nihon Hinyokika Gakkai Zasshi; 2010 Nov;101(7):749-53
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  • [Title] [Adenocarcinoma of the rete testis. A case report].
  • Adenocarcinoma of the rete testis is a rare malignant tumor with a poor prognosis.
  • About 60 cases of this adenocarcinoma have been reported in the literature.
  • The diagnosis is often difficult and made incidentally.
  • Herein, we report a case of adenocarcinoma of the rete testis and review the literature.
  • Magnetic resonance imaging (MRI) showed a left hydrocele with central necrosis of the testis.
  • Positron emission tomography (PET) was performed in another hospital, and the patient was referred for a left testicular tumor, multiple lung metastases, and para-aorta lymph node metastasis.
  • Pathological examination revealed a hard whitish mass around the testis involving the epididymis and tunica vaginalis and spreading under the subcutaneous tissue.
  • Histological examination revealed adenocarcinoma in the hilum of the testis, which extended to the subcutaneous tissue but not to the surface of the scrotum.
  • The tunica albuginea was intact, and no invasion of carcinoma in the testis was seen.
  • After the histological diagnosis of adenocarcinoma of the rete testis was confirmed, computed tomography (CT) was performed and showed multiple pulmonary nodules and para-aortica lymph node swelling of 3 cm diameter.
  • Because the patient did not wish to receive chemotherapy or other aggressive treatment, he has been followed-up with palliative care since his diagnosis.
  • Although local recurrence has occurred 4 months later, he is still alive for 8 months since his diagnosis.
  • [MeSH-major] Adenocarcinoma / therapy. Testicular Neoplasms / therapy
  • [MeSH-minor] Aged, 80 and over. Humans. Lung Neoplasms / diagnosis. Lung Neoplasms / secondary. Lymphatic Metastasis. Magnetic Resonance Imaging. Male. Orchiectomy. Palliative Care. Positron-Emission Tomography. Tomography, X-Ray Computed

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  • (PMID = 21174741.001).
  • [ISSN] 0021-5287
  • [Journal-full-title] Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
  • [ISO-abbreviation] Nippon Hinyokika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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12. Maruschke M, Schmidt W, Casper J, Hakenberg OW: Ovarian type surface epithelial carcinoma of the testis with delayed metastatic spread. Urol Int; 2008;81(1):119-21
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  • [Title] Ovarian type surface epithelial carcinoma of the testis with delayed metastatic spread.
  • Ovarian type surface epithelial carcinomas of the testis and paratestis are rare.
  • A 67-year-old patient with a mucinous ovarian type surface carcinoma of the testis is presented.
  • [MeSH-major] Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / pathology. Testicular Neoplasms / diagnosis. Testicular Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / ultrasonography. Aged. Carcinoembryonic Antigen / metabolism. Female. Humans. Immunohistochemistry / methods. Lymphatic Metastasis. Male. Testis / pathology. Ultrasonography / methods

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  • [Copyright] (c) 2008 S. Karger AG, Basel.
  • (PMID = 18645284.001).
  • [ISSN] 1423-0399
  • [Journal-full-title] Urologia internationalis
  • [ISO-abbreviation] Urol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen
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13. Joos ZP, Pritchett TR, Porter CR, Isacson C, Picozzi V, Corman JM: Adenocarcinoma of the testicular adnexa presenting with metastatic disease. Can J Urol; 2006 Feb;13(1):2990-2
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  • [Title] Adenocarcinoma of the testicular adnexa presenting with metastatic disease.
  • Primary epididymal adenocarcinoma is a rare malignancy with fewer than 30 documented cases.
  • Histology confirmed the presence of primary paratesticular adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Retroperitoneal Neoplasms / secondary. Testicular Neoplasms / pathology

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  • (PMID = 16515756.001).
  • [ISSN] 1195-9479
  • [Journal-full-title] The Canadian journal of urology
  • [ISO-abbreviation] Can J Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Canada
  • [Number-of-references] 11
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14. Sheridan T, Herawi M, Epstein JI, Illei PB: The role of P501S and PSA in the diagnosis of metastatic adenocarcinoma of the prostate. Am J Surg Pathol; 2007 Sep;31(9):1351-5
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  • [Title] The role of P501S and PSA in the diagnosis of metastatic adenocarcinoma of the prostate.
  • BACKGROUND: Adenocarcinoma of the prostate can present as metastatic carcinoma with no known primary.
  • The tissue microarray contains 78 cases of metastatic prostatic adenocarcinoma, 20 cases of primary prostatic adenocarcinoma, and 20 cases of benign prostate tissue from the peripheral zone as well as samples of benign brain, pancreas, kidney, thyroid, testis, skeletal muscle, and fibroconnective tissue.
  • A small subset of metastatic prostatic adenocarcinoma shows significant differences in staining intensity and extent for PSA and P501S and, therefore, combined use of these markers may result in increased sensitivity for detecting prostatic origin.
  • [MeSH-major] Adenocarcinoma / diagnosis. Membrane Proteins / analysis. Neoplasms, Unknown Primary / diagnosis. Prostate-Specific Antigen / analysis. Prostatic Neoplasms / diagnosis

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  • (PMID = 17721190.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P50 CA58236
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Membrane Proteins; 0 / prostein; EC 3.4.21.77 / Prostate-Specific Antigen
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15. Shigematsu Y, Hanagiri T, Shiota H, Kuroda K, Baba T, Mizukami M, So T, Ichiki Y, Yasuda M, So T, Takenoyama M, Yasumoto K: Clinical significance of cancer/testis antigens expression in patients with non-small cell lung cancer. Lung Cancer; 2010 Apr;68(1):105-10
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  • [Title] Clinical significance of cancer/testis antigens expression in patients with non-small cell lung cancer.
  • Cancer/testis antigens (CT antigens) are thought to be suitable targets for antigen-specific immunotherapy, because of the cancer-specific expression except for the testis among various normal tissues and no-expression of HLA class I in the testis.
  • Both of MAGE-A3 and MAGE-A4 were expressed more frequently in squamous cell carcinoma than in adenocarcinoma (p<0.01).
  • KK-LC-1 was expressed in 32.1% of patients with adenocarcinoma and in 36.5% of patients with squamous cell carcinoma.
  • [MeSH-major] Antigens, Neoplasm / metabolism. Carcinoma, Non-Small-Cell Lung / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Disease Progression. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Sex Factors. Survival Analysis. Testis / metabolism

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  • [Copyright] Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19545928.001).
  • [ISSN] 1872-8332
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Antigens, Neoplasm
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16. Kuo CY, Wen MC, Wang J, Jan YJ: Signet-ring stromal tumor of the testis: a case report and literature review. Hum Pathol; 2009 Apr;40(4):584-7
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  • [Title] Signet-ring stromal tumor of the testis: a case report and literature review.
  • Primary signet-ring stromal tumor of the testis is extremely rare.
  • Herein, we present a case of testicular signet-ring stromal tumor with positive immunostain for CD99, which has not been reported previously.
  • The most important differential diagnosis of signet-ring stromal tumor is metastatic signet-ring cell carcinoma because of its different management and prognosis.
  • Fortunately, signet-ring stromal tumors have a well-defined growth pattern, bland histological features, no mucin production, and immunoreaction to vimentin rather than cytokeratin, all of which help pathologists to rule out metastatic adenocarcinoma.
  • [MeSH-major] Sex Cord-Gonadal Stromal Tumors / pathology. Testicular Neoplasms / pathology

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  • (PMID = 18835626.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules
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17. Ruiz JM, Sanchis CM, López PC, Navarro HP, Moreno MJ, Sánchez AS, Tobarra MA, Rodríguez JA: Metastasis to the tunica vaginalis testis from a primary mucinous tumor of the cecum. Arch Esp Urol; 2010 Apr;63(3):235-8
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  • [Title] Metastasis to the tunica vaginalis testis from a primary mucinous tumor of the cecum.
  • OBJECTIVES: We review the literature about secondary testicular tumors.
  • METHODS: We present the case of a patient with a metastatic mucus-secreting testicular tumor who presented in the emergency room with symptoms of acute scrotum 10 months after surgery for a mixed tumor of the cecum.
  • Our patient died 21 months after the initial diagnosis CONCLUSIONS: Testicular metastases and mucus-secreting intestinal tumor metastases are rare.
  • [MeSH-major] Adenocarcinoma, Mucinous / secondary. Cecal Neoplasms / pathology. Testicular Neoplasms / secondary

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  • (PMID = 20436228.001).
  • [ISSN] 1576-8260
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
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18. Lin CY, Jwo SC, Lin CC: Primary testicular actinomycosis mimicking metastatic tumor. Int J Urol; 2005 May;12(5):519-21
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  • [Title] Primary testicular actinomycosis mimicking metastatic tumor.
  • We report a rare case of right primary testicular actinomycosis presenting as multiple testicular lesions mimicking a metastatic tumor in a 71-year-old patient with gastric adenocarcinoma.
  • Preoperative diagnosis is difficult.
  • The enlarged and inflamed testis was removed by orchiectomy and testicular actinomycosis was diagnosed after pathological examination.
  • We illustrate this case, though it is rare, to alert pathologists and clinicians to the possible occurrence of primary testicular actinomycosis mimicking metastatic lesions in a cancer patient.
  • We also reviewed the published literature and found that the treatment of choice for testicular actinomycosis was orchiectomy.
  • [MeSH-major] Actinomycosis / diagnosis. Orchitis / diagnosis
  • [MeSH-minor] Actinomyces / isolation & purification. Adenocarcinoma / complications. Adenocarcinoma / diagnosis. Aged. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Neoplasm Metastasis / diagnosis. Orchiectomy. Stomach Neoplasms / complications. Stomach Neoplasms / diagnosis. Testis / microbiology. Testis / pathology. Testis / ultrasonography

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  • (PMID = 15948759.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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19. Alois M, Valentina P, Andreas G: The "Krukrnberg" tumor in male. Arch Esp Urol; 2005 Nov;58(9):971-3
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  • We report a case of metastasis to the testis and epididymis by gastric cancer that can be the analogue in male.
  • METHODS: A patient, submitted to total gastrectomy for a poorly differentiated gastric adenocarcinoma (TNM stage: pT3 GIII N+ M 1) developed one year later a painful swelling of the right hemiscrotum and groin.
  • The palpation revealed a painful mandarine-like mass conglobated in the right testis and epididymis, with a further mass at the external inguinal-ring and multiple little nodes along the spermatic cord.
  • An inguinal orchifuniculectomy was performed and the histological tests described a poorly differentiated, microtubular adenocarcinoma, infiltrating the connective tissue, without spreading to the testis, that was properly structured.
  • The immune-histochemical results confirmed the diagnosis of an adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Epididymis. Genital Neoplasms, Male / secondary. Stomach Neoplasms / pathology. Testicular Neoplasms / secondary

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  • (PMID = 16430050.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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20. Mhawech P, Greloz V, Assaly M, Herrmann F: Immunohistochemical expression of 14-3-3 sigma protein in human urological and gynecological tumors using a multi-tumor microarray analysis. Pathol Int; 2005 Feb;55(2):77-82
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  • The most frequent expression was seen in squamous cell carcinoma of the cervix and urothelial bladder carcinoma, followed by prostatic and endometrial adenocarcinoma.
  • 14-3-3 sigma was able to distinguish prostate adenocarcinoma from urothelial bladder carcinoma, with an odds ratio of 0.028 (P = 0.001; 95% CI, 0.0003-0.222), and distinguish seminoma from embryonal carcinoma of the testis, with an odds ratio of 0.061 (P = 0.009; 95% CI, 0.007-0.5014).
  • [MeSH-minor] 14-3-3 Proteins. Adenocarcinoma / diagnosis. Carcinoma, Embryonal / diagnosis. Carcinoma, Transitional Cell / diagnosis. Diagnosis, Differential. Exoribonucleases. Female. Humans. Male. Odds Ratio. Prostatic Neoplasms / diagnosis. Seminoma / diagnosis. Testicular Neoplasms / diagnosis. Urologic Neoplasms / diagnosis

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  • (PMID = 15693853.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / 14-3-3 Proteins; 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; EC 3.1.- / Exonucleases; EC 3.1.- / Exoribonucleases; EC 3.1.- / SFN protein, human
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21. Venkitaraman R, George M, Weerasooriya S, Selva-Nayagam S: Late solitary testicular metastasis from rectal cancer. J Cancer Res Ther; 2010 Jan-Mar;6(1):89-91
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  • [Title] Late solitary testicular metastasis from rectal cancer.
  • Isolated testicular metastasis from rectal cancer is rare.
  • He developed a painless testicular nodule while on follow-up, five years after the diagnosis of primary rectal cancer.
  • Histopathology and immunohistochemistry of orchidectomy specimen were compatible with a metastatic adenocarcinoma of rectal origin.
  • Treatment of late isolated relapse in the testis needs to be ascertained.
  • [MeSH-major] Adenocarcinoma / secondary. Rectal Neoplasms / pathology. Testicular Neoplasms / secondary

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  • (PMID = 20479555.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] U3P01618RT / Fluorouracil
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22. Manikandan R, Nathaniel C, Reeve N, Brough RJ: Bilateral testicular metastases from prostatic carcinoma. Int J Urol; 2006 Apr;13(4):476-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral testicular metastases from prostatic carcinoma.
  • Testicular metastasis from carcinoma of the prostate is rare.
  • We report a case of carcinoma of the prostate with bilateral testicular metastases 7 years after the initial diagnosis.
  • Although testicular metastasis is uncommon, it should be considered when a patient presents with a lump in the testis, particularly in a patient known to have another primary malignancy.
  • [MeSH-major] Adenocarcinoma / secondary. Prostatic Neoplasms / pathology. Testicular Neoplasms / secondary
  • [MeSH-minor] Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged. Orchiectomy. Prostate-Specific Antigen / blood

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  • (PMID = 16734881.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] EC 3.4.21.77 / Prostate-Specific Antigen
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23. Matsuzaki M, Nakano M, Komatsu H, Ohashi K: [Aortic replacement during post chemotherapy retroperitoneal residual tumor resection for nonseminomatous germ cell tumor: a case report]. Hinyokika Kiyo; 2005 Dec;51(12):831-4
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  • His left testis was hard and swollen.
  • Under the diagnosis of testicular tumor and retroperitoneal lymph node metastasis, left radical orchiectomy was performed and the histopathological examination showed mature teratoma.
  • Histopathological diagnosis was cystopapillary adenocarcinoma and mature teratoma.
  • [MeSH-major] Adenocarcinoma, Papillary / surgery. Aorta, Abdominal / surgery. Lymph Node Excision. Lymph Nodes / pathology. Neoplasms, Multiple Primary. Teratoma / surgery. Testicular Neoplasms / surgery

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  • (PMID = 16440734.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin; BEP protocol
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24. Monappa V, Rao AC, Krishnanand G, Mathew M, Garg S: Adenomatoid tumor of tunica albuginea mimicking seminoma on fine needle aspiration cytology: a case report. Acta Cytol; 2009 May-Jun;53(3):349-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The epididymis is the most common site of involvement; however, it can also arise from the tunica albuginea, spermatic cord, tunica vaginalis and testis.
  • We report the cytologic features of a case of adenomatoid tumor arising from testicular tunica albuginea.
  • Histopathologic examination confirmed the diagnosis as adenomatoid tumor of tunica albuginea.
  • It is thus important to consider this tumor in the differential diagnosis of scrotal swellings.
  • [MeSH-major] Adenomatoid Tumor / pathology. Seminoma / pathology. Testicular Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / secondary. Adult. Biopsy, Fine-Needle. Cystadenoma, Papillary / diagnosis. Diagnosis, Differential. Epithelium / pathology. Humans. Hyperplasia / diagnosis. Male. Mesothelioma / diagnosis. Orchiectomy

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  • (PMID = 19534283.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Janssen S, Bernhards J, Anastasiadis AG, Bruns F: Solitary testicular metastasis from prostate cancer: a rare case of isolated recurrence after radical prostatectomy. Anticancer Res; 2010 May;30(5):1747-9
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  • [Title] Solitary testicular metastasis from prostate cancer: a rare case of isolated recurrence after radical prostatectomy.
  • An isolated testicular metastasis of PC is rare.
  • Unfortunately, the PSA level rose again, accompanied by a swelling of the left testis approximately one month after radiotherapy.
  • A unilateral orchiectomy was then performed, presenting a testicular metastasis of the PC.
  • In particular, rare metastatic sites such as the testis or the epididymis should be taken into account before treatment of biochemical recurrence is initiated.
  • [MeSH-major] Prostatectomy / methods. Prostatic Neoplasms / diagnosis. Prostatic Neoplasms / pathology. Testicular Neoplasms / diagnosis. Testicular Neoplasms / secondary
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Adenocarcinoma / therapy. Aged. Epididymis / pathology. Humans. Immunohistochemistry / methods. Male. Neoplasm Metastasis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / therapy. Orchiectomy / methods. Prostate-Specific Antigen / blood. Recurrence


26. Antic T, Staerkel G: Mediastinal epithelioid hemangioendothelioma metastatic to lymph nodes and pleural fluid: report of a case. Diagn Cytopathol; 2010 Feb;38(2):113-6
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  • Involvement of numerous sites of the body, including visceral organs, soft tissue, testis, skeleton, brain, meninges, and skin have been described.
  • The patient had a complex history of papillary renal cell carcinoma, papillary thyroid carcinoma, and Waldenstrom's hyperglobulinemia making the diagnosis of metastatic epithelioid hemangioendothelioma difficult.
  • [MeSH-minor] Adenocarcinoma, Papillary / complications. Aged. Biopsy, Fine-Needle. Carcinoma, Renal Cell / complications. Female. Humans. Immunohistochemistry. Kidney Neoplasms / complications. Leukemia, Lymphocytic, Chronic, B-Cell / complications. Stomach Neoplasms / complications. Thyroid Neoplasms / complications. Thyroiditis / complications. Waldenstrom Macroglobulinemia / complications

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  • (PMID = 19688765.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Winstanley AM, Landon G, Berney D, Minhas S, Fisher C, Parkinson MC: The immunohistochemical profile of malignant mesotheliomas of the tunica vaginalis: a study of 20 cases. Am J Surg Pathol; 2006 Jan;30(1):1-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Malignant mesotheliomas of the testis arise from the tunica vaginalis, formed from the evagination of the abdominal peritoneum into the scrotum.
  • Testicular series are uncommon, usually derived from previous case studies and literature reviews.
  • Archival testicular malignant mesothelioma specimens from 1959 to 2004 were collected from hospitals throughout the United Kingdom and from the authors' own archives.
  • In all cases, the morphologic light microscopy criteria for a diagnosis of malignant mesothelioma were present.
  • However, two tumors were later excluded from the study because of diffuse strong positive immunostaining with CK20 and BerEp4 and an ultrastructural appearance of adenocarcinoma.
  • Four of the 18 cases were examined by electron microscopy, which revealed long thin microvilli supporting a diagnosis of malignant mesothelioma.
  • This study has shown that the immunocytochemical profile of testicular malignant mesotheliomas is similar to those arising in the pleura, with diffuse positivity for calretinin, EMA, thrombomodulin, and CK7, and negative for CK20 and CEA.
  • However, histopathologists should be aware of the variability in CK5-6 staining in testicular specimens when compared with pleural mesotheliomas.
  • [MeSH-major] Biomarkers, Tumor / analysis. Mesothelioma / metabolism. Mesothelioma / ultrastructure. Testicular Neoplasms / metabolism. Testicular Neoplasms / ultrastructure

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  • (PMID = 16330935.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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28. Albino G, Nenna R, Inchingolo CD, Marucco EC: Hydrocele with surprise. Case report and rewiew of literature. Arch Ital Urol Androl; 2010 Dec;82(4):287-90

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  • INTRODUCTION: Hydrocele is a fluid collection between tunica vaginalis and testis.
  • Approximately 10% of testicular cancers occurs with a reactive hydrocele.
  • Rhabdomyosarcoma is the most common, followed by mesothelioma, adenocarcinoma and neuroblastoma.

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  • (PMID = 21341584.001).
  • [ISSN] 1124-3562
  • [Journal-full-title] Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
  • [ISO-abbreviation] Arch Ital Urol Androl
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
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29. Scalcione LR, Katz DS, Santoro MS, Mahboob S, Badler RL, Yung EY: Primary testicular lymphoma involving the spermatic cord and gonadal vein. Clin Nucl Med; 2009 Apr;34(4):222-3
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  • [Title] Primary testicular lymphoma involving the spermatic cord and gonadal vein.
  • We report a case of a 70-year-old man with a history of prostatic adenocarcinoma and a 3-month history of right hemiscrotal swelling.
  • Scrotal ultrasound revealed a heterogeneous right testicular mass.
  • Subsequent right radical orchiectomy and pathologic examination revealed a B-cell lymphoma, infiltrating the testicular parenchyma, spermatic cord, gonadal vessels, and adjacent soft-tissues.
  • [MeSH-major] Lymphoma / diagnosis. Lymphoma / radionuclide imaging. Spermatic Cord / pathology. Testicular Neoplasms / diagnosis. Testicular Neoplasms / radionuclide imaging. Testis / blood supply. Veins / pathology

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  • (PMID = 19300051.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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30. Li FQ, Liu Q, Han YL, Wu B, Yin HL: Sperm protein 17 is highly expressed in endometrial and cervical cancers. BMC Cancer; 2010;10:429
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  • BACKGROUND: Sperm protein 17 (Sp17) is a highly conserved mammalian protein in the testis and spermatozoa and has been characterized as a tumor-associated antigen in a variety of human malignancies.
  • This study aimed to investigate the expression of Sp17 in endometrial and cervical cancer specimens, its possible correlation with the pathological characteristics, and its value in the diagnosis and immunotherapy of the related cancers.
  • [MeSH-major] Adenocarcinoma / metabolism. Antigens, Surface / metabolism. Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / metabolism. Carrier Proteins / metabolism. Endometrial Neoplasms / metabolism. Uterine Cervical Neoplasms / metabolism

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  • (PMID = 20712874.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Surface; 0 / Biomarkers, Tumor; 0 / Carrier Proteins; 0 / Immunoglobulin G; 0 / SPA17 protein, human
  • [Other-IDs] NLM/ PMC2931487
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31. Athanasiou A, Vanel D, El Mesbahi O, Theodore C, Fizazi K: Non-germ cell tumours arising in germ cell tumours (teratoma with malignant transformation) in men: CT and MR findings. Eur J Radiol; 2009 Feb;69(2):230-5
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Other histological types of malignant transformation included adenocarcinoma (n=3) and bronchoalveolar carcinoma (n=1).
  • RESULTS: Non-GCT malignant transformation was identified in the retroperitoneum (5), testis (3), mediastinum (3), peritoneum (2) and lungs (1).
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Magnetic Resonance Imaging. Teratoma / diagnosis. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Teratoma.
  • MedlinePlus Health Information. consumer health - CT Scans.
  • MedlinePlus Health Information. consumer health - MRI Scans.
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  • (PMID = 19056194.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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