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1. H'ng MW, Kwek JW, Teo CH, Cheong DM: Cystic degeneration of ductal adenocarcinoma of the pancreatic tail. Singapore Med J; 2009 Mar;50(3):e91-3
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  • [Title] Cystic degeneration of ductal adenocarcinoma of the pancreatic tail.
  • We present a 54-year-old Chinese man with a tumour at the pancreatic tail associated with a presumed cystic splenic lesion.
  • Histological examination showed a pancreatic ductal adenocarcinoma with extensive cystic degeneration and invasion of the spleen, a rare imaging presentation for such a tumour.
  • [MeSH-major] Carcinoma, Pancreatic Ductal / pathology. Pancreas / pathology. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Abdominal Pain / diagnosis. Fatal Outcome. Humans. Male. Middle Aged

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  • (PMID = 19352559.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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2. Fujimori N, Nakamura T, Oono T, Igarashi H, Takahata S, Nakamura M, Tanaka M, Hayashi A, Aishima S, Ishigami K, Ogoshi K, Ito T, Takayanagi R: Adenocarcinoma involving the whole pancreas with multiple pancreatic masses. Intern Med; 2010;49(15):1527-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma involving the whole pancreas with multiple pancreatic masses.
  • Total pancreatectomy was performed under the diagnosis of double primary pancreatic carcinomas.
  • Macroscopic examination revealed 3 nodules: one each in the pancreatic head, body, and tail.
  • Incidentally, we also identified an adenocarcinoma of the common bile duct (CBD).
  • The final diagnosis was synchronous double cancer involving the whole pancreas and the CBD.
  • [MeSH-major] Adenocarcinoma / diagnosis. Common Bile Duct Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Pancreatic Neoplasms / diagnosis

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  • (PMID = 20686284.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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3. Yan HC, Wu YL, Chen LR, Gao SL: Resection of non-cystic adenocarcinoma in pancreatic body and tail. World J Gastroenterol; 2006 Sep 21;12(35):5726-8
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  • [Title] Resection of non-cystic adenocarcinoma in pancreatic body and tail.
  • AIM: To report the outcome of Chinese patents with non-cystic adenocarcinoma in pancreatic body and tail (NCAPBT) after resection and to discuss its surgical strategy.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreas / surgery. Pancreatic Neoplasms / surgery

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  • [Cites] Scand J Gastroenterol. 1995 Dec;30(12):1216-20 [9053977.001]
  • [Cites] Ann Surg. 1996 May;223(5):506-11; discussion 511-2 [8651741.001]
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  • (PMID = 17007030.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4088178
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4. Mirarchi M, De Raffele E, Lega S, Calculli L, Vaccari S, Cola B: [Synchronous adenocarcinoma of the sigmoid colon and multifocal intraductal papillary mucinous neoplasm of the pancreas in an elderly patient]. Chir Ital; 2009 May-Jun;61(3):357-67
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  • [Title] [Synchronous adenocarcinoma of the sigmoid colon and multifocal intraductal papillary mucinous neoplasm of the pancreas in an elderly patient].
  • [Transliterated title] Adenocarcinoma del colon e neoplasia papillare intraduttale mucinosa multifocale sincrona del pancreas in un paziente anziano: caso clinico e revisione della letteratura.
  • Intraductal papillary mucinous neoplasms are a well-recognized pathologic entity of the pancreas that is being reported with increasing frequency.
  • A 78-year-old man presented with rectal bleeding which led to the diagnosis of a stenosing adenocarcinoma of the sigmoid colon.
  • No metastatic lesions were present but a 30 mm intraductal papillary mucinous neoplasm with mural nodules was detected in the uncinate process of the pancreas.
  • Small diffused dilations of the side branches were present in the body and tail of the gland.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Papillary / pathology. Carcinoma, Pancreatic Ductal / pathology. Neoplasms, Multiple Primary / pathology. Pancreatic Neoplasms / pathology. Sigmoid Neoplasms / pathology

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  • (PMID = 19694240.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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5. Chang DT, Schellenberg D, Shen J, Kim J, Goodman KA, Fisher GA, Ford JM, Desser T, Quon A, Koong AC: Stereotactic radiotherapy for unresectable adenocarcinoma of the pancreas. Cancer; 2009 Feb 1;115(3):665-72
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  • [Title] Stereotactic radiotherapy for unresectable adenocarcinoma of the pancreas.
  • BACKGROUND: The authors report on the local control and toxicity of stereotactic body radiotherapy (SBRT) for patients with unresectable pancreatic adenocarcinoma.
  • METHODS: Seventy-seven patients with unresectable adenocarcinoma of the pancreas received 25 gray (Gy) in 1 fraction.
  • There was no difference in the 12-month FFLP rate based on tumor location (head/uncinate, 91% vs body/tail, 86%; P = .52).
  • CONCLUSIONS: SBRT for pancreatic adenocarcinoma was effective for local control with associated risk of toxicity and should be used with rigorous attention to quality assurance.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatic Neoplasms / surgery. Radiosurgery

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  • [Copyright] (c) 2008 American Cancer Society.
  • [CommentIn] Cancer. 2009 Feb 1;115(3):468-72 [19117338.001]
  • (PMID = 19117351.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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6. De Raffele E, Mirarchi M, Vaccari S, Santini D, Calculli L, Pendino GM, Cola B: [Echo-guided spleen-preserving resection of the pancreas tail for pancreatic intraductal papillary mucinous neoplasms]. Chir Ital; 2009 Sep-Dec;61(5-6):667-77
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  • [Title] [Echo-guided spleen-preserving resection of the pancreas tail for pancreatic intraductal papillary mucinous neoplasms].
  • [Transliterated title] Resezione della coda del pancreas "spleen preserving" ecoguidata per neoplasia intraduttale mucinosa (IPMN) del pancreas.
  • Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are a distinct entity with malignant potential, which may recur after surgical excision.
  • We report our technique of intraoperative US-guided resection of non-invasive IPMNs located in the tail of the pancreas with spleen and splenic vessel preservation.
  • Following adequate exposure of the distal pancreas, a thorough ultrasonographic examination of the parenchyma is accomplished to define the features of the neoplasia, its relationship with the main pancreatic duct and splenic vessels and to mark the transection line with electrocautery.
  • Dissection begins at the inferior edge of the pancreatic tail and proceeds in a lateral to medial direction up to the transection line.
  • Patient 1 was a 63-year-old male who underwent intraoperative US-guided resection of the pancreatic tail for an IPMN of the pancreatic tail measuring 28 mm with moderate dysplasia at histology, and was discharged 9 days after surgery.
  • Patient 2 was a 60-year-old male who underwent intraoperative US-guided resection of the pancreatic tail for an IPMN of the pancreatic tail measuring 30 mm with carcinoma in situ at histology, and was discharged 9 days after surgery.
  • Limited distal pancreatic resection with spleen and splenic vessel preservation is an adequate surgical technique for non-invasive IPMN of the tail of the pancreas.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Carcinoma, Papillary / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery. Pancreatic Neoplasms / ultrasonography. Spleen

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  • (PMID = 20380276.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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7. Limmathurotsakul D, Rerknimitr P, Korkij W, Noppakun N, Kullavanijaya P, Rerknimitr R: Metastatic mucinous cystic adenocarcinoma of the pancreas presenting as Sister Mary Joseph's nodule. JOP; 2007;8(3):344-9
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  • [Title] Metastatic mucinous cystic adenocarcinoma of the pancreas presenting as Sister Mary Joseph's nodule.
  • CONTEXT: Sister Mary Joseph's nodule usually represents metastatic cancers from gastrointestinal malignancy including adenocarcinoma of the pancreas.
  • Mucinous cystadenocarcinoma is a rare malignancy of the pancreas.
  • A CT scan showed a large cystic lesion with internal septation at the pancreatic tail.

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  • (PMID = 17495365.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / CA-19-9 Antigen; 0 / Carcinoembryonic Antigen
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8. Qian ZY, Miao Y, Dai CC, Xu ZK, Liu XL: [Combined multiple organ resection in 16 patients with adenocarcinoma of the body or tail of the pancreas]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2005 Oct;27(5):572-4
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  • [Title] [Combined multiple organ resection in 16 patients with adenocarcinoma of the body or tail of the pancreas].
  • OBJECTIVE: To investigate the feasibility and therapeutic results of multiple organ resection in patients with tumor of the body and tail of pancreas.
  • METHODS: The clinical and pathological data were analysed in 16 consecutive patients with neoplasm of the body and tail of pancreas from 1999 to 2004 retrospectively.
  • RESULTS: Multiple organ resection was performed in 6 cases of primary pancreatic adenocarcinoma of the body and tail (3 cases of pancreatic cancer, 2 cases of malignant glucagonoma, and 1 case of well-differentiated pancreatic stromal sarcoma) and 10 cases of extrapancreatic malignancy (4 cases of gastric cancer, 2 cases of gastric leiomyosarcoma, 1 case of duodenal cancer, and 3 cases of colon cancer of hepatic flexure).
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery

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  • (PMID = 16274034.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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9. Strasberg SM, Linehan DC, Hawkins WG: Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas: ability to obtain negative tangential margins. J Am Coll Surg; 2007 Feb;204(2):244-9
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  • [Title] Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas: ability to obtain negative tangential margins.
  • BACKGROUND: Positive resection margins and low lymph node counts are common in resections of cancers of the body and tail of the pancreas.
  • In 2003, we described a novel approach for resection of the pancreas called radical antegrade modular pancreatosplenectomy (RAMPS), which was directed toward these problems.
  • We now present results of treatment of patients with adenocarcinoma using RAMPS with particular reference to the ability of this procedure to obtain negative tangential margin rates.
  • CONCLUSIONS: RAMPS procedure can achieve negative tangential margins in a high percent of patients with resectable carcinoma of the body and tail of the pancreas.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery. Splenectomy / methods

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  • (PMID = 17254928.001).
  • [ISSN] 1072-7515
  • [Journal-full-title] Journal of the American College of Surgeons
  • [ISO-abbreviation] J. Am. Coll. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Murakami Y, Uemura K, Sudo T, Hayashidani Y, Hashimoto Y, Ohge H, Sueda T: Impact of adjuvant gemcitabine plus S-1 chemotherapy after surgical resection for adenocarcinoma of the body or tail of the pancreas. J Gastrointest Surg; 2009 Jan;13(1):85-92
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  • [Title] Impact of adjuvant gemcitabine plus S-1 chemotherapy after surgical resection for adenocarcinoma of the body or tail of the pancreas.
  • BACKGROUND: Few patients with pancreatic body or tail carcinoma are candidates for surgical resection, and the efficacy of postoperative adjuvant chemotherapy for patients with pancreatic body or tail carcinoma has not been elucidated.
  • The aim of this study was to determine the effect of adjuvant gemcitabine and S-1 therapy for patients with adenocarcinoma of the body or tail of the pancreas who had undergone surgical resection by distal pancreatectomy.
  • MATERIALS AND METHODS: Medical records of 34 patients with pancreatic body or tail carcinoma who underwent surgical resection were reviewed retrospectively.
  • CONCLUSION: Postoperative adjuvant gemcitabine plus S-1 chemotherapy may improve survival after surgical resection for pancreatic body or tail carcinoma.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antimetabolites, Antineoplastic / therapeutic use. Deoxycytidine / analogs & derivatives. Oxonic Acid / therapeutic use. Pancreatectomy / methods. Pancreatic Neoplasms / drug therapy. Tegafur / therapeutic use

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  • (PMID = 18704593.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 0W860991D6 / Deoxycytidine; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; B76N6SBZ8R / gemcitabine; EC 1.17.4.- / Ribonucleotide Reductases
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11. Christein JD, Kendrick ML, Iqbal CW, Nagorney DM, Farnell MB: Distal pancreatectomy for resectable adenocarcinoma of the body and tail of the pancreas. J Gastrointest Surg; 2005 Sep-Oct;9(7):922-7
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  • [Title] Distal pancreatectomy for resectable adenocarcinoma of the body and tail of the pancreas.
  • The study goal was to analyze outcome after distal pancreatectomy for three subtypes of adenocarcinoma to determine the role of en bloc resection in surgical management.
  • A secondary aim was to identify those clinicopathologic factors correlating with survival in an analysis limited to ductal adenocarcinoma.
  • Medical records of consecutive patients undergoing distal pancreatectomy for adenocarcinoma between 1987 and 2003 were reviewed.
  • Clinicopathologic factors for patients undergoing distal pancreatectomy for ductal adenocarcinoma were subjected to both univariate and multivariate survival analyses.
  • Ninety-three patients underwent resection for ductal adenocarcinoma (66, 71%), mucinous cystadenocarcinoma (18, 19%), or adenocarcinoma associated with intraductal papillary mucinous neoplasm (IPMN) (9, 10%).
  • Median survival was 15.5 months, 30.2 months, and 50.7 months for ductal adenocarcinoma, mucinous cystadenocarcinoma, and adenocarcinoma associated with IPMN, respectively.
  • For ductal adenocarcinoma, tumor size greater than 3.5 cm, age greater than 60 years, and stage were factors that correlated with survival on a univariate analysis.
  • Four patients with ductal adenocarcinoma were actual 5-year survivors.
  • Long-term survival for patients with cystadenocarcinoma or IPMN-associated adenocarcinoma can be anticipated.
  • While rare, long-term survival for patients with ductal adenocarcinoma after distal pancreatectomy can be achieved.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery

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  • (PMID = 16137585.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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12. Morgan KA, Adams DB: Solid tumors of the body and tail of the pancreas. Surg Clin North Am; 2010 Apr;90(2):287-307
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  • [Title] Solid tumors of the body and tail of the pancreas.
  • Solid lesions of the body and tail of the pancreas challenge all the diagnostic and technical skills of the modern gastrointestinal surgeon.
  • A preoperative evaluation includes a thorough history and a pancreas protocol CT scan, supplemented by MR imaging and EUS when needed, to differentiate between the various potential diagnoses.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatectomy. Pancreatic Neoplasms / surgery
  • [MeSH-minor] Autoimmune Diseases / diagnosis. Carcinoma, Neuroendocrine / surgery. Disease-Free Survival. Endosonography. Gastrinoma / diagnosis. Gastrinoma / mortality. Gastrinoma / surgery. Glucagonoma / diagnosis. Glucagonoma / surgery. Humans. Insulinoma / diagnosis. Laparoscopy. Magnetic Resonance Imaging. Pancreatitis / diagnosis. Prognosis. Somatostatinoma / diagnosis. Somatostatinoma / surgery. Tomography, X-Ray Computed. Vipoma / diagnosis. Vipoma / surgery

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  • (PMID = 20362787.001).
  • [ISSN] 1558-3171
  • [Journal-full-title] The Surgical clinics of North America
  • [ISO-abbreviation] Surg. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 125
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13. Viret F, Ychou M, Baey C, Bennouna J, Adenis A, Peiffert D, Mornex F, Celier P, Montoto-Grillot C, Ducreux M: A phase II study of radiation and docetaxel and cisplatin in the treatment of locally advanced pancreatic carcinoma. FNCLCC-ACCORD 09 /0201 trial. J Clin Oncol; 2009 May 20;27(15_suppl):4625

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The purpose of this phase II trial was to determine the efficacy and the toxicity of radiotherapy and docetaxel and cisplatin in histologically proven adenocarcinoma of the pancreas.
  • RESULTS: 51 pts (20 women and 31 men, with median age of 62 years) with disease considered to be unresectable but confined to pancreas area and celiac nodes were included between 06/10/2003 and 15/02/2008.
  • Location of the tumor: head (33 pts), body (13 pts), and tail (5 pts).

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  • (PMID = 27964209.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Ziegler M, Al-Haddad M, Schmidt CM: Prepancreatic portal vein in a patient with intestinal nonrotation: report of a case. J Gastrointest Surg; 2010 Apr;14(4):729-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a case of prepancreatic portal vein in a 71-year-old female with nonrotation who presented with a pancreatic adenocarcinoma in the tail of the pancreas who underwent a distal pancreatectomy and splenectomy.

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  • [Cites] Clin Radiol. 1995 Mar;50(3):174-6 [7889709.001]
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  • (PMID = 20066566.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Kim T, Grobmyer SR, Dixon LR, Hochwald SN: Isolated lymphoplasmacytic sclerosing pancreatitis involving the pancreatic tail. Am Surg; 2008 Jul;74(7):654-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isolated lymphoplasmacytic sclerosing pancreatitis involving the pancreatic tail.
  • CT imaging revealed a hypodense lesion in the tail of the pancreas.
  • We found a dense, inflammatory mass in the tail of the pancreas, which was removed via an open distal pancreatectomy with splenectomy.
  • Histologic analysis revealed a pancreas with sclerotic ducts and surrounding lymphoplasmacytic inflammation most consistent with lymphoplasmacytic sclerosing pancreatitis (LPSP).
  • LPSP, also termed autoimmune pancreatitis, is a benign disease of the pancreas, which can mimic pancreatic adenocarcinoma.
  • LPSP most commonly involves the head and, more uncommonly, the tail of the pancreas.
  • [MeSH-major] Pancreas / pathology. Pancreaticoduodenectomy / methods. Pancreatitis / pathology
  • [MeSH-minor] Chronic Disease. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Middle Aged. Sclerosis

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  • (PMID = 18646484.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Tozbikian G, Bloomston M, Stevens R, Ellison EC, Frankel WL: Accessory spleen presenting as a mass in the tail of the pancreas. Ann Diagn Pathol; 2007 Aug;11(4):277-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Accessory spleen presenting as a mass in the tail of the pancreas.
  • In this case report, we describe an accessory spleen that presented as a mass in the tail of the pancreas and mimicked a neoplasm.
  • Computerized axial tomography and magnetic resonance imaging scans demonstrated a hypervascular mass in the tail of the pancreas.
  • The clinical and radiological differential diagnosis included pancreatic mucinous cystic neoplasm, pancreatic endocrine neoplasm, solid pseudopapillary tumor, ductal adenocarcinoma, and metastasis.
  • [MeSH-major] Adenocarcinoma / diagnosis. Choristoma / pathology. Pancreatic Diseases / pathology. Pancreatic Neoplasms / diagnosis. Spleen
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Pancreas / pathology. Pancreas / surgery. Tomography, X-Ray Computed


17. Kanda M, Fujii T, Sahin TT, Kanzaki A, Nagai S, Yamada S, Sugimoto H, Nomoto S, Takeda S, Kodera Y, Morita S, Nakao A: Invasion of the splenic artery is a crucial prognostic factor in carcinoma of the body and tail of the pancreas. Ann Surg; 2010 Mar;251(3):483-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Invasion of the splenic artery is a crucial prognostic factor in carcinoma of the body and tail of the pancreas.
  • OBJECTIVES: A retrospective study was performed to determine the prognostic implications of invasion to the splenic vessels in pancreatic body and tail cancer.
  • SUMMARY BACKGROUND DATA: Involvement of the splenic artery (SA) and vein (SV) is frequently observed in carcinoma of the body and tail of the pancreas, but its correlation with various other clinicopathologic factors and prognosis has not been explored in detail.
  • METHODS: Fifty-one patients who had undergone distal pancreatectomy for invasive adenocarcinoma of the body and tail of the pancreas were discreetly selected from the prospective data base for analyses.
  • CONCLUSIONS: Our results indicated that the invasion of the SA, but not that of the SV, is a crucial prognostic factor in pancreatic body and tail cancer.
  • [MeSH-major] Adenocarcinoma / pathology. Pancreatic Neoplasms / pathology. Splenic Artery. Vascular Neoplasms / pathology

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  • (PMID = 20101172.001).
  • [ISSN] 1528-1140
  • [Journal-full-title] Annals of surgery
  • [ISO-abbreviation] Ann. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Chang SM, Yan ST, Wei CK, Lin CW, Tseng CE: Solitary concomitant endocrine tumor and ductal adenocarcinoma of pancreas. World J Gastroenterol; 2010 Jun 7;16(21):2692-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary concomitant endocrine tumor and ductal adenocarcinoma of pancreas.
  • Most reported cases are classified as mixed exocrine and endocrine carcinoma of the pancreas.
  • We report the first case of solitary concomitant endocrine tumor and ductal adenocarcinoma of the pancreas.
  • The tumor was fortuitously discovered in the pancreatic tail after a tumor survey panel.
  • The exocrine part showed a poorly-differentiated adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Pancreatic Ductal / pathology. Endocrine Gland Neoplasms / pathology. Pancreatic Neoplasms / pathology

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  • [Cites] West J Med. 1986 Jun;144(6):746-9 [3014756.001]
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  • (PMID = 20518094.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromogranin A; 0 / Hypoglycemic Agents; 0 / Synaptophysin; 9007-92-5 / Glucagon
  • [Other-IDs] NLM/ PMC2880785
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19. Hart B, Erickson R, LeBlanc C, Hix-Hernandez S, Shabahang M: Adenocarcinoma of the distal pancreas presenting as an intrathoracic mass. Curr Surg; 2006 Sep-Oct;63(5):330-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of the distal pancreas presenting as an intrathoracic mass.
  • Pancreatic masses within the body or tail usually have delayed diagnosis secondary to the lack of any early findings, which, in turn, leads to a higher incidence of involvement of adjacent structures, such as the superior mesenteric artery, portal vein, or superior mesenteric vein.
  • The authors report a case of advanced pancreatic adenocarcinoma in which the anomalous thoracic location of the organ resulted in the tumor being resectable.
  • [MeSH-major] Adenocarcinoma / diagnosis. Pancreatic Neoplasms / diagnosis

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  • (PMID = 16971204.001).
  • [ISSN] 0149-7944
  • [Journal-full-title] Current surgery
  • [ISO-abbreviation] Curr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Wu X, Tao R, Lei R, Han B, Cheng D, Shen B, Peng C: Distal pancreatectomy combined with celiac axis resection in treatment of carcinoma of the body/tail of the pancreas: a single-center experience. Ann Surg Oncol; 2010 May;17(5):1359-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distal pancreatectomy combined with celiac axis resection in treatment of carcinoma of the body/tail of the pancreas: a single-center experience.
  • The aim of this study was to assess the safety and efficacy of this extended procedure in treatment of advanced carcinoma of the body/tail of the pancreas.
  • METHODS: This was a retrospective analysis of 206 patients with carcinoma of the body/tail of the pancreas from January 2003 through June 2008.
  • CONCLUSIONS: DP combined with CA resection can be safely performed in certain patients with carcinoma of body/tail of the pancreas and significantly improves patient survival and quality of life.
  • [MeSH-minor] Adenocarcinoma. Adenocarcinoma, Clear Cell. Adenocarcinoma, Mucinous. Adult. Aged. Carcinoma, Acinar Cell. Female. Humans. Liver Neoplasms / secondary. Liver Neoplasms / surgery. Male. Middle Aged. Neoplasm Invasiveness. Postoperative Complications / diagnosis. Retrospective Studies. Survival Rate. Tomography, X-Ray Computed. Treatment Outcome

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  • [CommentIn] Ann Surg Oncol. 2011 Dec;18 Suppl 3:S244; author reply S245 [20967503.001]
  • (PMID = 20198445.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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21. Hsu JT, Yeh CN, Chen YR, Chen HM, Hwang TL, Jan YY, Chen MF: Adenosquamous carcinoma of the pancreas. Digestion; 2005;72(2-3):104-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenosquamous carcinoma of the pancreas.
  • BACKGROUND/AIMS: Adenosquamous carcinoma (ASC) of the pancreas is rare and correct preoperative diagnosis is difficult.
  • Case reports of ASC of the pancreas are sporadic and have typically employed small series.
  • This study investigated the clinicopathological features of 7 cases of ASC of the pancreas and reviewed the pertinent literature to elucidate this rare disease.
  • METHODOLOGY: Seven patients (4 men and 3 women; age range 38-79 years; median 66 years) with ASC of the pancreas who underwent surgical treatment at Chang Gung Memorial Hospital between February 1993 and April 2000 were retrospectively reviewed.
  • The tumors were located at the head of the pancreas in 4 patients (57.1%), at the body in 2, and at the tail in 2.
  • One patient had ASC at the body and tail.
  • CONCLUSIONS: Patients with ASC present symptoms similar to those of adenocarcinoma of the pancreas.

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  • [Copyright] Copyright (c) 2005 S. Karger AG, Basel.
  • (PMID = 16172546.001).
  • [ISSN] 0012-2823
  • [Journal-full-title] Digestion
  • [ISO-abbreviation] Digestion
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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22. Frozanpor F, Albiin N, Linder S, Segersvärd R, Lundell L, Arnelo U: Impact of pancreatic gland volume on fistula formation after pancreatic tail resection. JOP; 2010;11(5):439-43

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of pancreatic gland volume on fistula formation after pancreatic tail resection.
  • CONTEXT: Resection of the body and tail of the pancreas (distal pancreatectomy) is associated with high postoperative morbidity, most of which is due to leakage from the pancreatic transection surface.
  • The volume of the remaining pancreas and the technique of closure of the transected pancreas were found to affect this risk, thus allowing future preventive measures to be explored and evaluated in clinical trials.
  • [MeSH-major] Pancreas / pathology. Pancreas / surgery. Pancreatectomy / adverse effects. Pancreatic Fistula / etiology
  • [MeSH-minor] Adenocarcinoma / mortality. Adenocarcinoma / pathology. Adenocarcinoma / radiography. Adenocarcinoma / surgery. Adult. Aged. Cohort Studies. Computer Simulation. Female. Humans. Length of Stay. Male. Middle Aged. Organ Size / physiology. Pancreatic Neoplasms / mortality. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / radiography. Pancreatic Neoplasms / surgery. Postoperative Complications / epidemiology. Postoperative Complications / etiology. Postoperative Complications / mortality. Risk Factors. Tomography, X-Ray Computed

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  • (PMID = 20818111.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Italy
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23. Reddy SK, Tyler DS, Pappas TN, Clary BM: Extended resection for pancreatic adenocarcinoma. Oncologist; 2007 Jun;12(6):654-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extended resection for pancreatic adenocarcinoma.
  • Adenocarcinoma of the pancreas presents a number of therapeutic challenges.
  • TP should not be performed for most cases of adenocarcinoma of the pancreatic head because of the nominal incidence of lymph node involvement along the body and tail of the pancreas, the scarcity of multicentric disease, and the better management of pancreatic leaks after PD.
  • The disappointing experience with extended resections underscores the need for better adjuvant systemic strategies and the interdisciplinary care of patients with pancreatic adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatic Neoplasms / surgery

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  • (PMID = 17602057.001).
  • [ISSN] 1083-7159
  • [Journal-full-title] The oncologist
  • [ISO-abbreviation] Oncologist
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 55
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24. Han SL, Zhang WJ, Zheng XF, Shen X, Zeng QQ, Ke QH: Radical resection and outcome for malignant tumors of the pancreatic body and tail. World J Gastroenterol; 2009 Nov 14;15(42):5346-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radical resection and outcome for malignant tumors of the pancreatic body and tail.
  • AIM: To analyze the factors influencing radical (R0) resection rate and surgical outcome for malignant tumor of the pancreatic body and tail.
  • METHODS: The clinical and operative data and follow-up results of 214 pancreatic body and tail cancer patients were analyzed retrospectively.
  • RESULTS: One hundred and twenty/214 pancreatic body and tail cancer patients underwent surgical treatment; the overall resection rate was 59.2% (71/120), and the R0 resection rate was 40.8% (49/120).
  • The overall 1-, 3- and 5-year survival rates for pancreatic body and tail cancer patients were 12.7% (25/197), 7.6% (15/197) and 2.5% (5/197), respectively, and ductal adenocarcinoma patients had worse survival rates [15.0% (9/60), 6.7% (4/60) and 1.7% (1/60), respectively] than cystadenocarcinoma patients [53.8% (21/39), 28.2% (11/39) and 10.3% (4/39)] (P<0.01).
  • CONCLUSION: Early diagnosis is crucial for increasing the radical resection rate, and radical resection plays an important role in improving survival for pancreatic body and tail cancer patients.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Lymphatic Metastasis / pathology. Male. Middle Aged. Pancreas / pathology. Prognosis. Survival Analysis. Survival Rate. Treatment Outcome. Young Adult

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  • (PMID = 19908345.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2776864
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25. Adsay NV: Cystic neoplasia of the pancreas: pathology and biology. J Gastrointest Surg; 2008 Mar;12(3):401-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic neoplasia of the pancreas: pathology and biology.
  • In contrast with solid tumors, most of which are invasive ductal adenocarcinoma with dismal prognosis, cystic lesions of the pancreas are often either benign or low-grade indolent neoplasia.
  • The presence of ovarian-type stroma has now almost become a requirement for the diagnosis of MCN, and when defined as such, MCN is seen almost exclusively in women of perimenopausal age group as thick-walled multilocular cystic mass in the tail of the pancreas in contrast with IPMN which afflicts an elder population, both genders in almost equal numbers, and occur predominantly in the head of the organ.
  • In conclusion, cystic lesions in the pancreas constitute a biologically and pathologically diverse category most (but not all) of which are either benign or treatable diseases; however, a substantial subset, especially mucinous ones, has malignant potential that requires careful analysis.
  • [MeSH-minor] Adenocarcinoma, Mucinous / mortality. Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology. Carcinoma, Papillary / mortality. Carcinoma, Papillary / pathology. Cystadenoma / pathology. Cystadenoma, Serous / pathology. Dilatation, Pathologic. Humans. Necrosis

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  • (PMID = 17957438.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 19
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26. Koizumi K, Fujii T, Matsumoto A, Sugiyama R, Suzuki S, Sukegawa R, Ozawa K, Orii F, Taruishi M, Saitoh Y, Sotokawa M, Takada A: [Synchronous double invasive ductal carcinomas of the pancreas with multifocal branch duct intraductal papillary mucinous neoplasms of the pancreas]. Nihon Shokakibyo Gakkai Zasshi; 2009 Jan;106(1):98-105
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  • [Title] [Synchronous double invasive ductal carcinomas of the pancreas with multifocal branch duct intraductal papillary mucinous neoplasms of the pancreas].
  • CT scan revealed double tumors in the pancreatic head and body concomitant with multicystic lesions of the pancreas.
  • Final histological diagnosis was double invasive ductal carcinomas of the pancreas head and tail with multifocal branch duct intraductal papillary mucinous adenomas of the pancreas.
  • The present case suggests that entire pancreas might have malignant potential in patients with intraductal papillary mucinous neoplasms.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Carcinoma, Papillary / surgery. Neoplasms, Multiple Primary. Pancreatic Neoplasms / surgery

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  • (PMID = 19122428.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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27. Joo YE, Heo T, Park CH, Lee WS, Kim HS, Kim JC, Koh YS, Choi SK, Cho CK, Rew JS, Kim SJ: A case of osteoclast-like giant cell tumor of the pancreas with ductal adenocarcinoma: histopathological, immunohistochemical, ultrastructural and molecular biological studies. J Korean Med Sci; 2005 Jun;20(3):516-20
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  • [Title] A case of osteoclast-like giant cell tumor of the pancreas with ductal adenocarcinoma: histopathological, immunohistochemical, ultrastructural and molecular biological studies.
  • Osteoclast-like giant cell tumor of the pancreas is a very rare neoplasm, of which the histiogenesis remains controversial.
  • An abdominal computerized tomography revealed the presence of a large cystic mass, arising from the tail of pancreas.
  • In addition, there was a small area of moderately to well differentiated ductal adenocarcinoma.
  • The final pathologic diagnosis was osteoclast-like giant cell tumor of the pancreas with ductal adenocarcinoma.
  • [MeSH-minor] Antigens, CD / analysis. Antigens, Differentiation, Myelomonocytic / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Keratins / analysis. Microscopy, Electron. Middle Aged. Mucin-1 / analysis. Proliferating Cell Nuclear Antigen / analysis. Vimentin / analysis

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  • (PMID = 15953882.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Mucin-1; 0 / Proliferating Cell Nuclear Antigen; 0 / Vimentin; 68238-35-7 / Keratins
  • [Other-IDs] NLM/ PMC2782216
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28. Kawakami H, Kuwatani M, Fujiya Y, Uebayashi M, Konishi K, Makiyama H, Hashino S, Kubota K, Itoh T, Asaka M: [A case of granulocyte-colony stimulating factor producing ductal adenocarcinoma of the pancreas]. Nihon Shokakibyo Gakkai Zasshi; 2007 Feb;104(2):233-8
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  • [Title] [A case of granulocyte-colony stimulating factor producing ductal adenocarcinoma of the pancreas].
  • We report a case of pancreatic ductal adenocarcinoma producing granulocyte-colony stimulating factor (G-CSF).
  • An abdominal CT scan revealed masses in the pancreatic body to the tail, and both lobes of the liver.
  • A biopsy specimen of the hepatic tumor demonstrated metastatic poorly differentiated adenocarcinoma.
  • The diagnosis of autopsy was pancreatic ductal adenocarcinoma.
  • The final diagnosis was G-CSF-producing pancreatic carcinoma.
  • [MeSH-major] Adenocarcinoma / metabolism. Carcinoma, Pancreatic Ductal / metabolism. Granulocyte Colony-Stimulating Factor / biosynthesis. Pancreatic Neoplasms / metabolism

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  • (PMID = 17283419.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Interleukin-6; 143011-72-7 / Granulocyte Colony-Stimulating Factor
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29. Fieger AJ, Demmel N, Mündel DF, Schenck RM, Harnisch T, Nüssler NC: [Carcinoma of the pancreas at the site of an intraductal papillary mucinous neoplasia]. Zentralbl Chir; 2009 Apr;134(2):182-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Carcinoma of the pancreas at the site of an intraductal papillary mucinous neoplasia].
  • Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are intraductally located, mucin-producing cystic neoplasms of the pancreas with a malignant potential.
  • We report about a 54-year-old female who underwent segmental resection of the pancreas for non-invasive IPMN.
  • Three years later a highly suspicious tumour of the pancreatic tail was detected during routine follow-up.
  • Resection of the pancreatic tail was performed.
  • The histological analysis revealed an adenocarcinoma.
  • This case suggests the development of a pancreatic carcinoma from a non-invasive IPMN and raises the question about the extent of surgery of non-invasive IPMNs of the pancreas.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma, Pancreatic Ductal / surgery. Cystadenoma, Mucinous / surgery. Cystadenoma, Papillary / surgery. Neoplasms, Multiple Primary / surgery
  • [MeSH-minor] Female. Humans. Middle Aged. Pancreas / pathology. Pancreatectomy. Reoperation

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  • (PMID = 19382053.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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30. Schmidt CM, Matos JM, Bentrem DJ, Talamonti MS, Lillemoe KD, Bilimoria KY: Acinar cell carcinoma of the pancreas in the United States: prognostic factors and comparison to ductal adenocarcinoma. J Gastrointest Surg; 2008 Dec;12(12):2078-86
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  • [Title] Acinar cell carcinoma of the pancreas in the United States: prognostic factors and comparison to ductal adenocarcinoma.
  • OBJECTIVE: Our objective was to compare a large population of patients with ACC to pancreatic ductal cell adenocarcinoma (DCC) in order to determine distinguishing characteristics and to assess survival.
  • Patients with ACC were more likely to be male, white, and have larger tumor size, no nodal involvement, or pancreatic tail tumors.

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  • (PMID = 18836784.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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31. Gleisner AL, Assumpcao L, Cameron JL, Wolfgang CL, Choti MA, Herman JM, Schulick RD, Pawlik TM: Is resection of periampullary or pancreatic adenocarcinoma with synchronous hepatic metastasis justified? Cancer; 2007 Dec 1;110(11):2484-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is resection of periampullary or pancreatic adenocarcinoma with synchronous hepatic metastasis justified?
  • Specifically, the role of hepatic resection for metastatic periampullary or pancreatic adenocarcinoma remains controversial.
  • METHODS: Between 1995 and 2005, 1563 patients underwent surgical resection for periampullary carcinoma (n=608 patients) or pancreatic adenocarcinoma (head, n=905 patients; tail, n=50 patients).
  • RESULTS: Of the 1563 patients who underwent resection of periampullary or pancreatic adenocarcinoma, 22 patients (1.4%) underwent simultaneous hepatic resection for synchronous liver metastasis.
  • The primary tumor site was ampullary (n=1 patient ), duodenal (n=2 patients), distal bile duct (n=2 patients), or pancreas (head, n=10 patients; tail, n=7 patients).
  • [MeSH-major] Adenocarcinoma / surgery. Liver Neoplasms / secondary. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy

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  • [Copyright] Copyright (c) 2007 American Cancer Society.
  • (PMID = 17941009.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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32. Ulla Rocha JL, Alvarez Sanchez MV, Paz Esquete J, Fernandez Salgado E, Alvarez Alvarez C, Vazquez Sanluis MJ, Ledo Barro L, Vazquez Astray E: Evaluation of the bilio-pancreatic region using endoscopic ultrasonography in patients referred with and without abdominal pain and CA 19-9 serum level elevation. JOP; 2007;8(2):191-7
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  • In each case, the parameters recorded were: levels of CA 19-9 one week before EUS, results from other imaging techniques (US, helical CT), and final diagnosis according to pathological and/or clinical evolution criteria.
  • In patients with abdominal pain, EUS showed chronic pancreatitis in 6 cases and adenocarcinoma of the tail of the pancreas in the remaining patient.
  • EUS was useful in studying patients with idiopathic abdominal pain and a slight elevation of CA 19-9 since it allowed us to detect chronic pancreatitis and even early adenocarcinoma of the pancreatic tail.
  • [MeSH-minor] Acute Disease. Adenocarcinoma / pathology. Adenocarcinoma / ultrasonography. Biomarkers, Tumor / blood. Biopsy, Fine-Needle. Humans. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / ultrasonography. Retrospective Studies

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  • (PMID = 17356242.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-19-9 Antigen
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33. Minami Y, Hasuike Y, Takeda Y, Tsujinaka T: Metachronous double cancer of the gallbladder and pancreas associated with pancreaticobiliary maljunction. J Hepatobiliary Pancreat Surg; 2008;15(3):330-3
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  • [Title] Metachronous double cancer of the gallbladder and pancreas associated with pancreaticobiliary maljunction.
  • On the present admission, ultrasonography (US) and computed tomography (CT) demonstrated a large mass, 60 mm in size, in the pancreatic tail.
  • Endoscopic retrograde cholangiopancreatography (ERCP) showed obstruction of the main pancreatic duct in the tail of the pancreas and revealed that the pancreatic duct was joined to the bile duct 25 mm above the papilla of Vater.
  • Histological examination revealed moderately differentiated ductal adenocarcinoma that had invaded to the proper muscle of the stomach.
  • Double cancer of the gallbladder and pancreas in a patient with pancreaticobiliary maljunction is rare.
  • Although the etiology of cancer of the pancreas associated with pancreaticobiliary maljunction is unclear, we should pay close attention to the pancreas as well as the biliary tract during the long-term follow-up of patients with pancreaticobiliary maljunction after they have undergone a choledochojejunostomy.
  • [MeSH-major] Adenocarcinoma / complications. Common Bile Duct / abnormalities. Neoplasms, Second Primary / complications. Pancreatic Ducts / abnormalities. Pancreatic Neoplasms / complications

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  • (PMID = 18535774.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 9
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34. Chen B, Hu S, Wang L, Wachtel MS, Frezza EE: Extended pancreatectomy with en bloc resection of the celiac axis for locally advanced cancer of pancreatic body and tail. Hepatogastroenterology; 2008 Nov-Dec;55(88):2252-5
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  • [Title] Extended pancreatectomy with en bloc resection of the celiac axis for locally advanced cancer of pancreatic body and tail.
  • At present, most surgeons will not resect the pancreas if there is involvement of celiac axis.
  • We present the case of a 67 yo male with pancreatic body and tail cancer invading the celiac axis treated by extended pancreatectomy, splenectomy, partial resection of proximal portion of jejunum and transverse colon, and left adrenalectomy with en bloc resection of celiac axis.
  • The case demonstrates that a procedure that may offer cure of locally advanced pancreas cancer may also completely resolve abdominal pain.
  • [MeSH-major] Adenocarcinoma / pathology. Pancreatectomy / methods. Pancreatic Neoplasms / surgery

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  • (PMID = 19260516.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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35. Sakpal SV, Sexcius L, Babel N, Chamberlain RS: Agenesis of the dorsal pancreas and its association with pancreatic tumors. Pancreas; 2009 May;38(4):367-73
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  • [Title] Agenesis of the dorsal pancreas and its association with pancreatic tumors.
  • Morphogenesis of the pancreas is a complex process; nevertheless, congenital anomalies are rare.
  • At embryogenesis, the pancreas develops from the endoderm-lined dorsal and ventral buds of the duodenum.
  • The ventral bud gives rise to the lower head and uncinate process of the pancreas; whereas, the dorsal bud gives rise to the upper head, isthmus, body, and tail of the pancreas.
  • Rarely, developmental failure of the dorsal pancreatic bud at embryogenesis results in the agenesis of the dorsal pancreas--neck, body, and tail.
  • Even rarer is the association of pancreatic tumors with agenesis of the dorsal pancreas.
  • In addition to citing our case, we provide a comprehensive review on agenesis of the dorsal pancreas and its association with pancreatic tumors.
  • [MeSH-major] Pancreas / abnormalities. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / diagnosis. Carcinoma, Pancreatic Ductal / surgery. Carcinoma, Papillary / diagnosis. Carcinoma, Papillary / surgery. Diagnosis, Differential. Humans. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 19390403.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Bachmann J, Michalski CW, Bergmann F, Büchler MW, Kleeff J, Friess H: Metastasis of rectal adenocarcinoma to the pancreas. Two case reports and a review of the literature. JOP; 2007;8(2):214-22
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  • [Title] Metastasis of rectal adenocarcinoma to the pancreas. Two case reports and a review of the literature.
  • Nonetheless, a variety of extrapancreatic tumors can involve the pancreas and may manifest with different clinicopathological characteristics.
  • In the first case, computed tomography showed a cystic mass in the pancreas but fine-needle biopsy followed by cytopathological analysis revealed only necrotic tissue.
  • In the other patient, magnetic resonance tomography showed a hypodense structure in the pancreatic body/tail.
  • CONCLUSION: In patients with a history of a malignant tumor, a newly diagnosed mass in the pancreas--although rare--should raise the suspicion of metastatic disease.
  • [MeSH-major] Adenocarcinoma / secondary. Pancreatic Neoplasms / secondary. Rectal Neoplasms / pathology

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  • (PMID = 17356246.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 103
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37. Murakami Y, Uemura K, Ohge H, Hayashidani Y, Sudo T, Sueda T: Intraductal papillary-mucinous neoplasms and mucinous cystic neoplasms of the pancreas differentiated by ovarian-type stroma. Surgery; 2006 Sep;140(3):448-53

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraductal papillary-mucinous neoplasms and mucinous cystic neoplasms of the pancreas differentiated by ovarian-type stroma.
  • BACKGROUND: Intraductal papillary-mucinous neoplasms (IPMN) and mucinous cystic neoplasms (MCN) of the pancreas have similar clinicopathologic findings.
  • RESULTS: IPMNs consisted of 32 adenomas, 12 borderline neoplasms, 13 adenocarcinomas in situ, and 13 invasive adenocarcinomas; MCNs included 6 adenomas and 1 invasive adenocarcinoma.
  • The location of the pancreatic mass differed, with 76% 0f IPMNs occurring in the head, while 86% of MCNs occurred in the body or tail.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma, Mucinous / pathology. Adenoma / pathology. Carcinoma, Pancreatic Ductal / pathology. Carcinoma, Papillary / pathology. Stromal Cells / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Disease Progression. Female. Humans. Male. Middle Aged. Ovary / cytology. Prognosis. Retrospective Studies. Survival Rate

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  • [CommentIn] Surgery. 2007 Apr;141(4):545-6 [17383536.001]
  • (PMID = 16934608.001).
  • [ISSN] 0039-6060
  • [Journal-full-title] Surgery
  • [ISO-abbreviation] Surgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Jang HW, Park WK, Chang JC, Kim JW, Bae YK, Choi JH, Yun SS, Lee DS: [Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas]. Korean J Gastroenterol; 2006 Nov;48(5):355-9
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  • [Title] [Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas].
  • Undifferentiated carcinoma with osteoclast-like giant cells is a rare neoplasm of exocrine pancreas.
  • On computed tomography, one case showed a well enhancing solid tumor with low density and the other was showed a mainly cystic tumor with peripheral enhancement in the body and tail of the pancreas.
  • In one case, there were small foci of adenocarcinoma components in the periphery of the tumor.

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  • (PMID = 17132925.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
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39. Lin HL, Kuo LC, Chen CW, Lin YK, Lee WC: Pancreatic tail cancer with sole manifestation of left flank pain: a very rare presentation. Kaohsiung J Med Sci; 2008 Jun;24(6):324-7
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  • [Title] Pancreatic tail cancer with sole manifestation of left flank pain: a very rare presentation.
  • The symptoms can be quite vague and various depending on the location of cancer in the pancreas.
  • The anatomic site distribution is 78% in the head of the pancreas, 11% in the body, and 11% in the tail.
  • Pancreatic cancer is rarely detected in the early stage, and it is very uncommon to diagnose pancreatic tail cancer during an emergency department visit.
  • The manifestation of pancreatic tail cancer as left flank pain is very rare and has seldom been identified in the literature.
  • We present a case of pancreatic tail cancer with the sole manifestation of dull left flank pain.
  • Radiographic evaluation with computed tomography was performed, and pancreatic tail tumor with multiple metastases was found unexpectedly.
  • We review the literature and discuss this rare presentation of pancreatic tail cancer.
  • [MeSH-major] Flank Pain / diagnosis. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Fatal Outcome. Female. Humans. Liver Neoplasms / pathology. Liver Neoplasms / secondary. Medical Oncology / methods. Middle Aged. Neoplasm Metastasis. Prognosis. Tomography, X-Ray Computed

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  • (PMID = 18635419.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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40. Ren FY, Shao CW, Zuo CJ, Lu JP: CT features of colloid carcinomas of the pancreas. Chin Med J (Engl); 2010 May 20;123(10):1329-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CT features of colloid carcinomas of the pancreas.
  • BACKGROUND: Colloid carcinomas of the pancreas have better prognosis than ordinary ductal adenocarcinoma, and preoperative distinction of colloid carcinoma from other pancreatic tumors is valuable for patient therapeutic planning and prognosis assessment.
  • Seven patients with pathologically proven colloid carcinoma of the pancreas were included.
  • Five tumors were located in the pancreatic head, and the other two in body and tail respectively.
  • CONCLUSIONS: Colloid carcinomas of the pancreas appear as round or labular masses with great percent of cystic areas and slight hyp-attenuation on unenhanced CT and peripheral and internal meshlike progressive delayed enhancement on enhanced CT.
  • [MeSH-major] Adenocarcinoma, Mucinous / radiography. Pancreatic Neoplasms / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 20529590.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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41. Yamamoto J, Saiura A, Koga R, Seki M, Katori M, Kato Y, Sakamoto Y, Kokudo N, Yamaguchi T: Improved survival of left-sided pancreas cancer after surgery. Jpn J Clin Oncol; 2010 Jun;40(6):530-6
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  • [Title] Improved survival of left-sided pancreas cancer after surgery.
  • OBJECTIVE: Resective therapeutic strategy for left-sided pancreatic adenocarcinoma is open to debate.
  • The post-resection outcomes and factors influencing post-resection survival for adenocarcinoma of the body and tail of the pancreas were analyzed to determine the effectiveness of surgery.
  • METHODS: A total of 73 patients with adenocarcinoma of the body or tail of the pancreas who underwent resection between 1994 and June 2007 were evaluated for overall survival.
  • CONCLUSIONS: Appropriate patient selection and accurate surgical technique with postoperative adjuvant therapy could benefit survival of patients with carcinoma of the pancreas body and tail.
  • [MeSH-major] Adenocarcinoma / mortality. Adenocarcinoma / surgery. Pancreatic Neoplasms / mortality. Pancreatic Neoplasms / surgery

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  • (PMID = 20363769.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
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42. Xu J, Liang Z, Hao S, Zhu L, Ashish M, Jin C, Fu D, Ni Q: Pancreatic adenocarcinoma: dynamic 64-slice helical CT with perfusion imaging. Abdom Imaging; 2009 Nov;34(6):759-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pancreatic adenocarcinoma: dynamic 64-slice helical CT with perfusion imaging.
  • Thus, in lesions of the tissues of the pancreas, this offers to increase the accuracy of CT diagnosis.
  • In this study, our aim was to explore the perfusion characteristics of normal pancreas and pancreatic adenocarcinoma.
  • METHODS: Dynamic 64-slice helical CT was conducted in 36 patients with non-pancreatic disease and in 40 patients with histopathologically proven pancreatic adenocarcinoma.
  • RESULTS: There was no significant difference noted between the distribution of BF, BV, and PS values in different regions of the pancreas, namely the head, neck, body, and tail (P > 0.05).
  • The BF, BV, and PS of normal pancreas were recorded as 135.24 +/- 48.36 ml min(-1) 100 g(-1), 200.55 +/- 54.96 ml 100 g(-1), and 49.75 +/- 24.27 ml min(-1) 100 g(-1), respectively.
  • BF, BV, and PS values of the tumor tissue of pancreatic adenocarcinoma decreased significantly compared to normal pancreas (P < 0.05).
  • CONCLUSIONS: Normal pancreas appears homogenous on perfusion CT.
  • A significant decrease of BF, BV, and PS was observed in pancreatic adenocarcinoma.
  • Dynamic 64-slice helical CT with perfusion imaging should be considered a potential modality to increase the accuracy of CT diagnosis for pancreatic adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / radiography. Pancreatic Neoplasms / radiography. Tomography, Spiral Computed / methods
  • [MeSH-minor] Case-Control Studies. Contrast Media. Female. Humans. Iohexol. Male. Middle Aged. Pancreas / blood supply. Pancreas / radiography. Pancreaticoduodenectomy. Prospective Studies

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  • (PMID = 19672566.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 4419T9MX03 / Iohexol
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43. Altinel D, Basturk O, Sarmiento JM, Martin D, Jacobs MJ, Kooby DA, Adsay NV: Lipomatous pseudohypertrophy of the pancreas: a clinicopathologically distinct entity. Pancreas; 2010 Apr;39(3):392-7
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  • [Title] Lipomatous pseudohypertrophy of the pancreas: a clinicopathologically distinct entity.
  • One such condition, which is poorly defined in the literature, is referred to as lipomatous pseudohypertrophy (LPH) of the pancreas.
  • RESULTS: Four patients underwent surgical resection, 3 of which were diagnosed preoperatively by radiology as having ductal adenocarcinoma.
  • The fifth patient has been placed on watchful waiting.Two tumors were in the pancreatic head, one in the tail, one in the uncinate process, and one demonstrated diffuse involvement.
  • CONCLUSION: Lipomatous pseudohypertrophy of the pancreas is a distinct entity characterized by localized/diffuse replacement of pancreatic parenchyma with mature adipose tissue.
  • It forms a pseudotumor that may be difficult to distinguish clinically from pancreatic adenocarcinoma.
  • This entity should be considered when evaluating patients with a new diagnosis of a hypodense pancreatic neoplasm on imaging.

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  • (PMID = 19904221.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA062924; None / None / / P50 CA062924-12; United States / NCI NIH HHS / CA / P50 CA062924-12; United States / NCI NIH HHS / CA / P50-CA62924
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS317488; NLM/ PMC3164317
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44. Ikuta S, Aihara T, Yasui C, Iida H, Yanagi H, Mitsunobu M, Kakuno A, Yamanaka N: Large mucinous cystic neoplasm of the pancreas associated with pregnancy. World J Gastroenterol; 2008 Dec 21;14(47):7252-5
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  • [Title] Large mucinous cystic neoplasm of the pancreas associated with pregnancy.
  • Mucinous cystic neoplasms (MCNs) of the pancreas occur mostly in females and are potentially sex hormone-sensitive.
  • She was thereafter diagnosed with missed abortion and a computed tomography scan showed that the lesion was a cystic tumor 18 cm in diameter originating from the pancreatic tail.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Pancreatic Neoplasms / diagnosis. Pregnancy Complications, Neoplastic / diagnosis

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  • (PMID = 19084943.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
  • [Other-IDs] NLM/ PMC2776886
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45. Koufuji K, Shirouzu K, Aoyagi K, Yano S, Miyagi M, Imaizumi T, Takeda J: Surgery and clinicopathological features of gastric adenocarcinoma involving the esophago-gastric junction. Kurume Med J; 2005;52(3):73-9
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  • [Title] Surgery and clinicopathological features of gastric adenocarcinoma involving the esophago-gastric junction.
  • To clarify the optimal operative procedure for gastric adenocarcinoma involving the esophago-gastric junction (EGJ), we investigated 49 cases with an upper gastric cancer invading the esophagus who underwent surgical treatment in our department during the period from 1991 to 2000.
  • We performed combined resection of the body and tail of the pancreas and the spleen in 7 cases.
  • One of these 7 cases had direct invasion to the pancreas and 6 cases had remarkable metastasis to the lymph nodes along the splenic artery.
  • Splenectomy preserving the pancreas was done in 24 cases.
  • Based on these results, we recommend distal esophagectomy with total gastrectomy, and occasional combined resection of the spleen and the diaphragm through a left thoraco-abdominal approach for advanced gastric adenocarcinoma involving the EGJ.
  • [MeSH-major] Adenocarcinoma / surgery. Esophageal Neoplasms / surgery. Esophagogastric Junction. Stomach Neoplasms / surgery

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  • (PMID = 16422172.001).
  • [ISSN] 0023-5679
  • [Journal-full-title] The Kurume medical journal
  • [ISO-abbreviation] Kurume Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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46. Hioki M, Nakagohri T, Ikumoto T, Gotohda N, Takahashi S, Konishi M, Kojima M, Kinoshita T: Intraductal tubular carcinoma of the pancreas: case report with review of literature. Anticancer Res; 2010 Nov;30(11):4435-41
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  • [Title] Intraductal tubular carcinoma of the pancreas: case report with review of literature.
  • Further imaging studies revealed a relatively clear-margined tumor totally occupying the main pancreatic duct (MPD) from the head to the tail of the pancreas (maximum diameter 10 cm) without mucin hypersecretion.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Pancreatic Ductal / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 21115890.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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47. Sakamoto H, Kitano M, Komaki T, Imai H, Kamata K, Kimura M, Takeyama Y, Kudo M: Small invasive ductal carcinoma of the pancreas distinct from branch duct intraductal papillary mucinous neoplasm. World J Gastroenterol; 2009 Nov 21;15(43):5489-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Small invasive ductal carcinoma of the pancreas distinct from branch duct intraductal papillary mucinous neoplasm.
  • This report describes a case of small adenocarcinoma of the pancreas distinct from branch duct intraductal papillary mucinous neoplasm (IPMN) in which investigation by EUS took place every 6 mo and diagnosis was made accurately by additional CEH-EUS during the follow-up of the branch duct IPMN.
  • However, after 2 years EUS demonstrated a low echoic area distinct from the branch duct IPMN which was vaguely discernible by EUS, and accurate sizing and differential diagnosis were considered difficult on the EUS imaging.
  • The histopathological diagnosis was adenocarcinoma (10 mm) in the pancreatic tail, distinct from the branch duct IPMN of the pancreatic body.
  • EUS and CEH-EUS may play an important role in the correct diagnosis of small pancreatic tumors, including synchronous and metachronous occurrence of IPMN and ductal adenocarcinoma of the pancreas.
  • [MeSH-major] Carcinoma, Pancreatic Ductal / diagnosis. Endosonography / methods. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / classification. Adenocarcinoma / diagnosis. Adenocarcinoma, Mucinous / classification. Adenocarcinoma, Mucinous / diagnosis. Aged. Female. Gastroenterology / methods. Humans. Medical Oncology / methods. Neoplasm Invasiveness. Neoplasms, Second Primary / classification. Neoplasms, Second Primary / diagnosis. Treatment Outcome

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  • (PMID = 19916181.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2778107
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48. Goh BK, Ooi LL, Kumarasinghe MP, Tan YM, Cheow PC, Chow PK, Chung YF, Wong WK: Clinicopathological features of patients with concomitant intraductal papillary mucinous neoplasm of the pancreas and pancreatic endocrine neoplasm. Pancreatology; 2006;6(6):520-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological features of patients with concomitant intraductal papillary mucinous neoplasm of the pancreas and pancreatic endocrine neoplasm.
  • BACKGROUND/AIMS: The occurrence of concomitant pancreatic endocrine neoplasm (PEN) and intraductal papillary neoplasm (IPMN) of the pancreas has rarely been reported.
  • The median size of the endocrine neoplasms was 14 mm (range 2-30) and they occurred in the head (n = 3), body (n = 2) and tail (n = 5).
  • The IPMNs were found in the tail (n = 4), head (n = 3), head and body (n = 1), body (n = 1) and the entire pancreas (n = 1).
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Neuroendocrine / pathology. Carcinoma, Pancreatic Ductal / pathology. Carcinoma, Papillary / pathology. Neoplasms, Second Primary / pathology. Pancreatic Neoplasms / pathology

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  • [Copyright] Copyright 2006 S. Karger AG, Basel and IAP.
  • (PMID = 17124434.001).
  • [ISSN] 1424-3903
  • [Journal-full-title] Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
  • [ISO-abbreviation] Pancreatology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromogranins; 0 / Synaptophysin
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49. Vadalà S, Aronica G, Biondi A, Magnano V, Valastro M, Li Volti G, Cordio S, Giannone G: Distal pancreatectomy with en bloc resection of the celiac axis for pancreatic adenocarcinoma. Clin Ter; 2009;160(4):287-90
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  • [Title] Distal pancreatectomy with en bloc resection of the celiac axis for pancreatic adenocarcinoma.
  • Subsequently, Mayumi et al. and Kimura et al. adopted this approach for locally advanced adenocarcinoma of pancreatic body.
  • We are here describing this technique in case of adenocarcinoma of pancreatic body with infiltration of celiac axis achieving also gastric preservation.
  • CT scan showed a 3 cm mass in the body of pancreas infiltrating the origin of celiac axis, causing obstructive atrophy of pancreatic tail.
  • Appleby operation can increase the resectability of locally advanced cancer of the body and tail of the pancreas and offers not only a better life quality for patients but also perfect pain relief.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery

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  • (PMID = 19795078.001).
  • [ISSN] 1972-6007
  • [Journal-full-title] La Clinica terapeutica
  • [ISO-abbreviation] Clin Ter
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
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50. Sperti C, Polizzi ML, Moro M, Beltrame V, Pedrazzoli S: Middle-preserving pancreatectomy: an interesting procedure for pancreas-sparing resection. JOP; 2010;11(3):258-61
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  • [Title] Middle-preserving pancreatectomy: an interesting procedure for pancreas-sparing resection.
  • CONTEXT: Total pancreatectomy is the treatment of choice for multicentric diseases involving the head and the body-tail of the pancreas.
  • A borderline mixed type IPMN of the head and chronic pancreatitis of the tail were found at pathological examination.
  • CONCLUSION: A middle-preserving pancreatectomy can be performed safely for multicentric IPMNs involving the head and the body-tail of the gland.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Carcinoma, Papillary / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods

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  • (PMID = 20442523.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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51. Lee S, Hwang HI, Yum SM, Lee WS, Park CH, Kim HS, Choi SK, Rew JS: [Accessory splenic infarction presenting as a hemorrhagic tumor in the pancreas]. Korean J Gastroenterol; 2008 Jul;52(1):48-51
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  • [Title] [Accessory splenic infarction presenting as a hemorrhagic tumor in the pancreas].
  • Computed tomography imaging of abdomen demonstrated a hemorrhagic high attenuation with enhancing solid portion in the tail of pancreas.
  • The clinical and radiological differential diagnosis included pancreatic mucinous cystic neoplasm, pancreatic endocrine neoplasm, solid pseudopapillary tumor, ductal adenocarcinoma, and metastasis.
  • In this case report, we first describe a symptomatic accessory splenic infarction which presented as a hemorrhagic mass in the tail of pancreas mimicking pancreatic neoplasm.
  • [MeSH-major] Pancreatic Diseases / diagnosis. Splenic Infarction / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Hemorrhage / etiology. Humans. Pancreas / pathology. Pancreas / surgery. Pancreatectomy. Pancreatic Neoplasms / diagnosis. Spleen / pathology. Tomography, X-Ray Computed

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  • (PMID = 19077492.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
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52. Itoi T, Sofuni A, Itokawa F, Kurihara T, Tsuchiya T, Ishii K, Tsuji S, Ikeuchi N, Arisaka Y, Moriyasu F: Initial experience of peroral pancreatoscopy combined with narrow-band imaging in the diagnosis of intraductal papillary mucinous neoplasms of the pancreas (with videos). Gastrointest Endosc; 2007 Oct;66(4):793-7
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  • [Title] Initial experience of peroral pancreatoscopy combined with narrow-band imaging in the diagnosis of intraductal papillary mucinous neoplasms of the pancreas (with videos).
  • OBJECTIVE: To evaluate the clinical usefulness of POPS by using NBI for the diagnosis of IPMN.
  • Furthermore, NBI identified skip tumor lesions in the tail of pancreas, which were not detected by conventional POPS.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Carcinoma, Pancreatic Ductal / diagnosis. Carcinoma, Papillary / diagnosis. Endoscopy, Gastrointestinal / methods. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Biopsy. Diagnosis, Differential. Endoscopes, Gastrointestinal. Equipment Design. Follow-Up Studies. Humans. Male. Retrospective Studies

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  • (PMID = 17905024.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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53. Yasuda M, Senju T, Aratake Y, Nakamura T, Horikawa Y, Yokota M, Sumii T, Iguchi H, Funakoshi A, Nishiyama K: [A case of pancreatic ductal adenocarcinoma with rapid progress in a young man]. Nihon Shokakibyo Gakkai Zasshi; 2006 Feb;103(2):194-9
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  • [Title] [A case of pancreatic ductal adenocarcinoma with rapid progress in a young man].
  • Various imaging studies showed a solid tumor (4cm in diameter) in the tail of the pancreas, multiple hypovascular tumors in liver.
  • Final diagnosis of autopsy was pancreatic ductal adenocarcinoma.
  • Pancreatic ductal adenocarcinoma in the young patients is rare, and we reported this case in addition to consideration on literature.
  • [MeSH-major] Adenocarcinoma / diagnosis. Pancreatic Ducts. Pancreatic Neoplasms / diagnosis

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  • (PMID = 16506669.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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54. Kubota K, Kita J, Rokkaku K, Iwasaki Y, Sawada T, Imura J, Fujimori T: Ectopic hepatocellular carcinoma arising from pancreas: a case report and review of the literature. World J Gastroenterol; 2007 Aug 21;13(31):4270-3
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  • [Title] Ectopic hepatocellular carcinoma arising from pancreas: a case report and review of the literature.
  • A 56-year-old man was found to have a pancreatic tail tumor.
  • With a tentative diagnosis of non-functional islet-cell tumor, the patient underwent resection of the pancreatic body and tail with splenectomy.
  • These results supported a diagnosis of HCC without any adenocarcinoma component.
  • The patient is currently doing well without any signs of recurrence in either the remaining pancreas or liver three years after surgery.
  • We report the rare case with ectopic HCC in the pancreas with a review of the literature.
  • [MeSH-major] Carcinoma, Hepatocellular. Choristoma / diagnosis. Liver Neoplasms. Pancreatic Neoplasms / diagnosis

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  • (PMID = 17696261.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers; 0 / CAM 5.2 antigen; 0 / Keratin-18; 68238-35-7 / Keratins
  • [Number-of-references] 33
  • [Other-IDs] NLM/ PMC4250631
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55. de Castro SM, Singhal D, Aronson DC, Busch OR, van Gulik TM, Obertop H, Gouma DJ: Management of solid-pseudopapillary neoplasms of the pancreas: a comparison with standard pancreatic neoplasms. World J Surg; 2007 May;31(5):1130-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of solid-pseudopapillary neoplasms of the pancreas: a comparison with standard pancreatic neoplasms.
  • BACKGROUND: Solid-pseudopapillary neoplasms (SPNs) of the pancreas are increasingly diagnosed, but the exact surgical management in terms of extent of the resection is not well defined.
  • Neoplasms were distributed equally among the pancreatic head (SPN 5 out of 12 patients versus PR 88%, p < 0.001) and corpus/tail (SPN 6 out of 12 patients versus PR 8%, p < 0.001).
  • The 5-year survival of SPN patients was 100% and is significantly better compared with survival of patients with pancreatic adenocarcinoma (12%, p < 0.001) and ampulla of Vater adenocarcinoma (22%, p = 0.005).
  • CONCLUSIONS: Patients with solid-pseudopapillary neoplasms of the pancreas present differently and the course of the disease is more benign.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / surgery

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  • [Cites] Surgery. 1995 Nov;118(5):821-8 [7482268.001]
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  • (PMID = 17429567.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2813543
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56. Okamura J, Sekine S, Nara S, Ojima H, Shimada K, Kanai Y, Hiraoka N: Intraductal carcinosarcoma with a heterologous mesenchymal component originating in intraductal papillary-mucinous carcinoma (IPMC) of the pancreas with both carcinoma and osteosarcoma cells arising from IPMC cells. J Clin Pathol; 2010 Mar;63(3):266-9
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  • [Title] Intraductal carcinosarcoma with a heterologous mesenchymal component originating in intraductal papillary-mucinous carcinoma (IPMC) of the pancreas with both carcinoma and osteosarcoma cells arising from IPMC cells.
  • Carcinosarcoma of the pancreas is extremely rare and its histogenesis is still unclear.
  • This is a report on a 64-year-old female patient with an intraductal carcinosarcoma arising from intraductal papillary-mucinous carcinoma (IPMC) in the pancreas tail.
  • Histologically, the tumour consisted of adenocarcinoma covering the luminal surface of the lesion with minimal stromal invasion, and osteosarcoma occupying the stroma.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology. Carcinosarcoma / pathology. Osteosarcoma / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 20203229.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / KRAS protein, human; 0 / Proto-Oncogene Proteins; EC 3.6.5.2 / ras Proteins
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57. Chiang KC, Hsu JT, Chen HY, Jwo SC, Hwang TL, Jan YY, Yeh CN: Multifocal intraductal papillary mucinous neoplasm of the pancreas--a case report. World J Gastroenterol; 2009 Feb 7;15(5):628-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multifocal intraductal papillary mucinous neoplasm of the pancreas--a case report.
  • Cystic neoplasms of the pancreas are relatively rare, comprising 10 percent of pancreatic cysts and only 1 percent of pancreatic cancers.
  • Cystic neoplasms include mucinous cystic neoplasms, serous cystadenomas, papillary cystic tumors, cystic islet cell tumors and intraductal papillary mucinous neoplasms of the pancreas (IPMNs).
  • The majority of IPMNs are located in the pancreatic head (75%) while the rest involves the body/tail regions.
  • Here we present a 72-year-old male diagnosed with IPMN (carcinoma in situ) in the pancreatic head and a branch duct type IPMN (duct atypia) in the pancreatic body and tail.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology

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  • (PMID = 19195068.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2653357
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58. Kang CM, Lee JW: Spleen preserving laparoscopic distal pancreatectomy with segmental resection of splenic artery in a solid pseudo papillary tumor of the pancreas. Hepatogastroenterology; 2009 Jul-Aug;56(93):1207-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spleen preserving laparoscopic distal pancreatectomy with segmental resection of splenic artery in a solid pseudo papillary tumor of the pancreas.
  • Laparoscopic distal pancreatectomy is suitable for benign and premalignant neoplasms located in the body and tail of the pancreas.
  • We present a case of 32-year-old female patient with a solid pseudopapillary tumor of the pancreas treated by spleen-preserving laparoscopic distal pancreatectomy with segmental resection of the splenic artery and splenic vein intact.
  • [MeSH-major] Adenocarcinoma, Papillary / surgery. Laparoscopy. Pancreatectomy / methods. Pancreatic Neoplasms / surgery. Splenic Artery / surgery

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  • (PMID = 19760971.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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59. Salla C, Chatzipantelis P, Konstantinou P, Karoumpalis I, Sakellariou S, Pantazopoulou A, Manika Z: Endoscopic ultrasound-guided fine-needle aspiration cytology in the diagnosis of intraductal papillary mucinous neoplasms of the pancreas. A study of 8 cases. JOP; 2007;8(6):715-24
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  • [Title] Endoscopic ultrasound-guided fine-needle aspiration cytology in the diagnosis of intraductal papillary mucinous neoplasms of the pancreas. A study of 8 cases.
  • CONTEXT: Intraductal papillary mucinous neoplasm (IPMN) is an increasingly recognized neoplasm of the pancreas, accounting for 5% of pancreatic neoplasms, it is considered difficult to diagnose by fine-needle aspiration (FNA) cytology.
  • OBJECTIVE: The aim of this study was to investigate the role of EUS-guided FNA cytology in the diagnosis of IPMN of the pancreas.
  • EUS/clinical findings, macroscopic/microscopic features of cell blocks and smears, and immunocytochemical stains accompanied by histopathologic diagnosis were recorded and studied.
  • RESULTS: EUS revealed hypoechoic masses in the head of pancreas (n=6) and in the body/tail (n=2), measuring from 16.6 to 35.8 mm.
  • The histological diagnosis confirmed the FNA cytology diagnosis: 3 malignant IPMNs, 2 benign IPMNs and 3 borderline IPMNs.
  • CONCLUSIONS: The characteristic pre-operative EUS findings and cytomorphologic features, in addition to the immunocytochemical profile, were accurate indications and coincided with the final/post-operative histological diagnosis of IPMN.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Papillary / diagnosis. Adenocarcinoma, Papillary / pathology. Pancreatic Neoplasms / diagnosis. Pancreatic Neoplasms / pathology

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  • (PMID = 17993724.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Mucins; EC 2.7.10.1 / Receptor, ErbB-2
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60. Albores-Saavedra J, Simpson KW, Bilello SJ: The clear cell variant of solid pseudopapillary tumor of the pancreas: a previously unrecognized pancreatic neoplasm. Am J Surg Pathol; 2006 Oct;30(10):1237-42
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  • [Title] The clear cell variant of solid pseudopapillary tumor of the pancreas: a previously unrecognized pancreatic neoplasm.
  • We report 3 cases of a previously undescribed variant of solid pseudopapillary tumor of the pancreas composed almost entirely of multivacuolated clear cells (>90%).
  • Two of the patients were young adult females with well-demarcated tumors involving the body and tail of the pancreas.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Carcinoma, Papillary / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 17001153.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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61. Shen ZL, Wang S, Ye YJ, Wang YL, Sun KK, Yang XD, Jiang KW: Carcinosarcoma of pancreas with liver metastasis combined with gastrointestinal stromal tumour of the stomach: is there a good prognosis with the complete resection? Eur J Cancer Care (Engl); 2010 Jan 1;19(1):118-23
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  • [Title] Carcinosarcoma of pancreas with liver metastasis combined with gastrointestinal stromal tumour of the stomach: is there a good prognosis with the complete resection?
  • We report a carcinosarcoma of the pancreas with liver metastasis combined with gastrointestinal stromal tumour (GIST) of the stomach in a 72-year-old woman who presented with right upper quadrant pain, nausea and vomiting.
  • The tumour in the head of pancreas was found to be grossly yellow-white, and it infiltrated the common bile duct and duodenum; the mass of the liver metastasis is solitary.
  • Pathologic examination showed two components separated from each other: one component was a conventional infiltrating pancreatic ductal adenocarcinoma, and the other component showed sarcomatous growth pattern composed of pleomorphic spindle cells.
  • The patient was obliged to be in hospital because of abnormal bowel function; moreover, surveillance CT scans performed at 1.5 months post-operatively showed multiple liver metastasis and recurrence in the tail of pancreas.
  • To our knowledge, this is the first experience report about surgical treatment of carcinosarcoma of pancreas with liver metastasis combined with GIST of the stomach.

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  • (PMID = 19486125.001).
  • [ISSN] 1365-2354
  • [Journal-full-title] European journal of cancer care
  • [ISO-abbreviation] Eur J Cancer Care (Engl)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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62. Eguchi H, Ishikawa O, Ohigashi H, Sasaki Y, Yamada T, Nakaizumi A, Uehara H, Takenaka A, Kasugai T, Imaoka S: Role of intraoperative cytology combined with histology in detecting continuous and skip type intraductal cancer existence for intraductal papillary mucinous carcinoma of the pancreas. Cancer; 2006 Dec 1;107(11):2567-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of intraoperative cytology combined with histology in detecting continuous and skip type intraductal cancer existence for intraductal papillary mucinous carcinoma of the pancreas.
  • Recent reports suggest a higher frequency of cancer recurrence in the remnant pancreas after surgical resection of IPMN.
  • METHODS: Both intraoperative histologic examination of the surgical margin and cytologic examination of the pancreatic juice from each pancreatic segment (head, body, or tail) were performed on 43 IPMN patients.
  • CONCLUSIONS: Using intraoperative frozen-section histology and pancreatic juice cytology, 18 out of 43 patients in the current study (42%) required additional resection of the pancreas.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Carcinoma, Papillary / surgery. Pancreatic Neoplasms / surgery

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  • [Copyright] (c) 2006 American Cancer Society.
  • (PMID = 17054109.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Lee HY, Lee DG, Chun K, Lee S, Song SY: Clear cell carcinoma of the pancreas--a case report and review of the literature. Cancer Res Treat; 2009 Sep;41(3):175-81
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  • [Title] Clear cell carcinoma of the pancreas--a case report and review of the literature.
  • Most of the malignant neoplasms of the pancreas demonstrate features that are consistent with adenocarcinoma.
  • According to the WHO classification, primary clear cell carcinoma of the pancreas is rare and it is classified as a "miscellaneous" carcinoma.
  • On the abdominal computed tomography (CT), we detected an abdominal mass involving the pancreas tail and liver, and clear cell carcinoma with rhabdoid feature was seen on the histologic evaluation.

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  • [Cites] Mod Pathol. 2008 Sep;21(9):1075-83 [18536653.001]
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  • (PMID = 19809568.001).
  • [ISSN] 1598-2998
  • [Journal-full-title] Cancer research and treatment : official journal of Korean Cancer Association
  • [ISO-abbreviation] Cancer Res Treat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2757667
  • [Keywords] NOTNLM ; Clear cell carcinoma / Pancreas / Rhabdoid tumor
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64. Chang KJ, Parasher G, Christie C, Largent J, Anton-Culver H: Risk of pancreatic adenocarcinoma: disparity between African Americans and other race/ethnic groups. Cancer; 2005 Jan 15;103(2):349-57
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  • [Title] Risk of pancreatic adenocarcinoma: disparity between African Americans and other race/ethnic groups.
  • BACKGROUND: African Americans have a higher incidence of pancreatic adenocarcinoma compared with non-Hispanic whites.
  • METHODS: The authors conducted a population-based retrospective analysis of all patients with pancreatic adenocarcinoma in both a regional and a statewide database between 1988 and 1998.
  • Their goal was to evaluate differences in incidence rates, clinical presentation, including age at diagnosis, gender, and tumor characteristics, and treatment among race/ethnic groups.
  • RESULTS: African Americans had a higher age-adjusted incidence rate of pancreatic adenocarcinoma (8.78) compared with non-Hispanic whites (5.89), Hispanics (5.09), Asians (4.75), and all race/ethnicities combined (5.82).
  • In general, males maintained a higher incidence rate of pancreatic adenocarcinoma than females across all race/ethnicities.
  • CONCLUSIONS: African Americans in California had a higher incidence rate of pancreatic adenocarcinoma, had a slightly higher risk of presenting with advanced-stage disease and with nonresectable tumors (i.e., tumors located in the body or tail of the pancreas), and underwent less surgical treatment than all other race/ethnicities.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / ethnology. Continental Population Groups / statistics & numerical data. Pancreatic Neoplasms / diagnosis. Pancreatic Neoplasms / ethnology

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  • [Copyright] (c) 2004 American Cancer Society.
  • [CommentIn] Cancer. 2005 Dec 1;104(11):2530-1; author reply 2531 [16240447.001]
  • (PMID = 15593353.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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65. Salla C, Chatzipantelis P, Konstantinou P, Karoumpalis I, Pantazopoulou A, Dappola V: Endoscopic ultrasound-guided fine-needle aspiration cytology diagnosis of solid pseudopapillary tumor of the pancreas: a case report and literature review. World J Gastroenterol; 2007 Oct 14;13(38):5158-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic ultrasound-guided fine-needle aspiration cytology diagnosis of solid pseudopapillary tumor of the pancreas: a case report and literature review.
  • We describe the clinical, imaging and cytopathological features of solid pseudopapillary tumor of the pancreas (SPTP) diagnosed by endoscopic ultrasound-guided (EUS-guided) fine-needle aspiration (FNA).
  • Computed tomography (CT) analysis revealed a mass of the pancreatic tail with solid and cystic consistency.
  • EUS confirmed the mass, both in body and tail of the pancreas, with distinct borders, which caused dilation of the peripheral part of the pancreatic duct (major diameter 3.7 mm).
  • Biopsy confirmed the above cytologic diagnosis.
  • EUS-guided FNA diagnosis of SPTP is accurate.
  • [MeSH-major] Carcinoma, Papillary / diagnosis. Carcinoma, Papillary / pathology. Pancreatic Neoplasms / diagnosis. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / pathology. Adolescent. Biopsy, Fine-Needle / methods. Carcinoma, Acinar Cell / diagnosis. Carcinoma, Acinar Cell / pathology. Diagnosis, Differential. Endosonography / methods. Female. Humans. Pancreas / pathology. Pancreas / ultrasonography

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  • (PMID = 17876886.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 59
  • [Other-IDs] NLM/ PMC4434650
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66. Sanada Y, Masumoto T, Nishimura R: An in situ carcinoma of the pancreas forming 2 invasive ductal carcinomas. Pancreas; 2005 Aug;31(2):198-9
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  • [Title] An in situ carcinoma of the pancreas forming 2 invasive ductal carcinomas.
  • Histopathologically, the main lesion that obstructed the main pancreatic duct and measured 2.0 cm in diameter was a moderately differentiated adenocarcinoma with marked neural invasion.
  • An accessory tumor measuring 0.8 cm in diameter was located in the pancreatic tail.
  • [MeSH-minor] Disease Progression. Humans. Male. Middle Aged. Pancreas / pathology

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  • (PMID = 16025010.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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67. Calculli L, Pezzilli R, Brindisi C, Morabito R, Casadei R, Zompatori M: Pancreatic and extrapancreatic lesions in patients with intraductal papillary mucinous neoplasms of the pancreas: a single-centre experience. Radiol Med; 2010 Apr;115(3):442-52
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  • [Title] Pancreatic and extrapancreatic lesions in patients with intraductal papillary mucinous neoplasms of the pancreas: a single-centre experience.
  • RESULTS: Pancreatic IPMN was localised in the head in 43 patients (30.3%), in the body in 13 (9.2%), in the tail in ten (7.0%), in the head-body in 17 (12.0%), in the body-tail in 15 (10.6%) diffuse throughout the gland in 44 (31.0%).
  • CONCLUSIONS: The majority of pancreatic and extrapancreatic cancers occur before the diagnosis of IPMNs is made and is not related to the type of IPMN.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology. Carcinoma, Papillary / pathology. Diagnostic Imaging. Neoplasms, Multiple Primary / pathology. Neoplasms, Second Primary / pathology. Pancreatic Neoplasms / pathology

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  • [Cites] Abdom Imaging. 2007 May-Jun;32(3):374-80 [16967247.001]
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  • (PMID = 20082228.001).
  • [ISSN] 1826-6983
  • [Journal-full-title] La Radiologia medica
  • [ISO-abbreviation] Radiol Med
  • [Language] eng; ita
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Contrast Media
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68. Ishigami S, Baba K, Mataki Y, Noma H, Maemura K, Shinchi H, Takao S, Natsugoe S, Aikou T: Pancreatic mucinous cyst adenocarcinoma producing CA 19-9. A case report. JOP; 2007;8(2):228-31
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  • [Title] Pancreatic mucinous cyst adenocarcinoma producing CA 19-9. A case report.
  • CONTEXT: We herein present a rare case of a mucinous cystic neoplasm of the pancreas producing CA 19-9 and the clinical implications are discussed.
  • Abdominal CT showed a large lobulated cystic tumor at the pancreatic tail.
  • A mucinous cystic neoplasm of the pancreas was diagnosed and elective surgery was performed.

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  • (PMID = 17356248.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-19-9 Antigen
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69. Iitaka D, Ikoma H, Kawaguchi T, Murayama Y, Komatsu S, Shiozaki A, Kuriu Y, Nakanishi M, Ichikawa D, Fujiwara H, Okamoto K, Ochiai T, Kokuba Y, Sonoyama T, Konishi H, Yoshikawa T, Otsuji E: [A case report--locally advanced pancreatic adenocarcinoma was resected after chemotherapy]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2358-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case report--locally advanced pancreatic adenocarcinoma was resected after chemotherapy].
  • Upper gastrointestinal endoscopy revealed circumferential stenosis in the fourth portion of the duodenum, while CT revealed a tumor with a diameter of 60 mm continuing as a single mass from the pancreatic body and tail to the fourth portion of the duodenum, and this was accompanied by findings that raised suspicions of circumferential invasion of the superior mesentric artery (SMA).
  • In the surgical findings, the tumor continued as a single mass from the pancreatic body and tail to the third portion of the duodenum, and the surrounding area exhibited marked fibrosis.
  • We performed a pancreatic tail resection along with combined resection of third and fourth portions of the duodenum, transverse colon and splenic flexure, and left adrenal gland.
  • Cancer invasion was not observed in any of the stripped surfaces surrounding the pancreas.
  • In this case, the treatment was initially started by considering the case as one of duodenal cancer, but the final results of a pathological diagnosis revealed that it was pancreatic cancer.
  • [MeSH-major] Adenocarcinoma / therapy. Pancreatic Neoplasms / therapy

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  • (PMID = 21224572.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents; 0 / Drug Combinations; 0 / Taxoids; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 15H5577CQD / docetaxel; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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70. Yendluri V, Centeno B, Springett GM: Pancreatic cancer presenting as a Sister Mary Joseph's nodule: case report and update of the literature. Pancreas; 2007 Jan;34(1):161-4
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  • In most series, the pancreas is the source of a SMJN in 7% to 9% of cases.
  • We report a case of pancreatic adenocarcinoma in which the initial presenting sign was a SMJN.
  • Including this case, we identified 57 cases of SMJN originating from the pancreas.
  • In contrast, 91% of these cases originated in the tail and body of the pancreas rather than the head of the pancreas.
  • This case emphasizes that pancreatic cancer should be considered in the differential diagnosis of umbilical metastasis.
  • [MeSH-major] Adenocarcinoma / secondary. Pancreatic Neoplasms / pathology. Skin Neoplasms / secondary. Umbilicus
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Humans. Laparoscopy. Tomography, X-Ray Computed

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  • (PMID = 17198200.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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71. Bandyopadhyay D, Kapadia CR, Da Costa PE: Pancreatic carcinoma: report of two cases presenting with unusual metastases. Indian J Gastroenterol; 2005 Mar-Apr;24(2):75-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report two patients with adenocarcinoma of the body and tail of the pancreas who presented with features localized to the metastatic sites.
  • [MeSH-major] Adenocarcinoma / secondary. Pancreatic Neoplasms / pathology

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  • (PMID = 15879657.001).
  • [ISSN] 0254-8860
  • [Journal-full-title] Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
  • [ISO-abbreviation] Indian J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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72. Spinelli GP, Zullo A, Romiti A, Di Seri M, Tomao F, Miele E, Spalletta B, Eramo A, Hassan C, Tomao S: Long-term survival in metastatic pancreatic cancer. A case report and review of the literature. JOP; 2006;7(5):486-91
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  • CASE REPORT: We report a rare case of a long-term survivor (more than 10 years) of metastatic carcinoma of the pancreas tail controlled with subsequent surgical and chemotherapeutic strategies with an acceptable performance status and quality of life.
  • [MeSH-major] Adenocarcinoma / mortality. Adenocarcinoma / secondary. Liver Neoplasms / mortality. Liver Neoplasms / secondary. Pancreatic Neoplasms / mortality. Pancreatic Neoplasms / pathology


73. Bach P, Möhring C, Krawzak HW, Goepel M: [Retroperitoneal extravasation as the primary symptom of a pancreatic carcinoma]. Urologe A; 2007 Nov;46(11):1548-50
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  • Adenocarcinoma of the pancreas has a low 5-year survival rate of approximately 5%.
  • In particular, individuals suffering from carcinomas located within the pancreatic tail are at high risk of a missed diagnosis.
  • An adenocarcinoma of the pancreatic tail was diagnosed in this case report based on a large retroperitoneal extravasation missing further symptoms.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnostic imaging. Extravasation of Diagnostic and Therapeutic Materials / diagnostic imaging. Pancreatic Neoplasms / diagnostic imaging
  • [MeSH-minor] Aorta, Abdominal / pathology. Diagnosis, Differential. Duodenum / pathology. Gastroenterostomy. Humans. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Palliative Care. Retroperitoneal Space / diagnostic imaging. Tomography, X-Ray Computed. Ureter / pathology. Urinoma / diagnostic imaging. Urography

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  • (PMID = 17786402.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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74. Machado NO, Chopra PJ, Al Hamdani A: Pancreatic metastasis from colon carcinoma nine years after a hemicolectomy managed by distal pancreatectomy. A review of the literature regarding the role and outcome of pancreatic resection for colorectal metastasis. JOP; 2010;11(4):377-81
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  • A case of colonic metastasis to the pancreas is reported and the literature is reviewed to assess the role and outcome of pancreatic resection for metastatic tumors from colorectal malignancy.
  • The lesion was reported to be adenocarcinoma, Dukes C, with involvement of the serosa and 3 lymph nodes.
  • A CT scan revealed a 6.8x4.8 cm mixed consistency lesion in the tail of the pancreas which, on fine needle aspiration cytology, was confirmed to be adenocarcinoma.
  • The time-interval between the diagnosis of colorectal cancer and the detection of pancreatic metastasis varies widely but is approximately 24 months.
  • [MeSH-minor] Adult. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / pathology. Colorectal Neoplasms / surgery. Female. Humans. Prognosis. Time Factors. Treatment Outcome

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  • [CommentIn] JOP. 2010;11(6):644-5; author reply 650 [21068505.001]
  • (PMID = 20601814.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 24
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75. Ibusuki M, Hiraoka T, Kanemitsu K, Takamori H, Tsuji T: Complete remission of pancreatic cancer after multiple resections of locally pancreatic recurrent sites and liver metastasis: report of a case. Surg Today; 2008;38(6):563-6
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  • A 60-year-old man was admitted to our hospital because of a neoplasm of the tail of the pancreas in April 1992.
  • The histopathological findings of specimens of the pancreas showed papillary adenocarcinoma, although the original pancreatic tumor also demonstrated areas of tubular adenocarcinoma.
  • Metastatic liver tumor showed tubular adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Adenocarcinoma, Papillary / surgery. Liver Neoplasms / secondary. Pancreatic Neoplasms / surgery

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  • (PMID = 18516541.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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76. Egawa N, Tu Y, Sanaka M, Kamisawa T: Family history of diabetes and pancreatic cancer. Pancreas; 2005 Jan;30(1):15-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Each group was further divided into 2 subgroups according to the presence of long-standing diabetes for at least 3 years before the diagnosis of the pancreatic cancer, and the 2 subgroups were also compared.
  • RESULTS: As compared with group non-FH, group FH was 4 years younger at the diagnosis of pancreatic cancer (61.33 +/- 9.00 vs. 65.46 +/- 10.48 years; P = 0.015) and showed a significant predilection for cancer of the pancreas body and/or tail (65.1% vs. 43.4%; P = 0.009).
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / genetics. Age Distribution. Aged. Family Health. Female. Humans. Male. Middle Aged. Regression Analysis. Risk Factors


77. Lin J, Jing X: Fine-needle aspiration of intrapancreatic accessory spleen, mimic of pancreatic neoplasms. Arch Pathol Lab Med; 2010 Oct;134(10):1474-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report the case of a 67-year-old asymptomatic man who had a 1.3-cm, incidentally detected, pancreatic tail mass.
  • By correlating the cytologic findings with the result of immunostaining, we rendered the diagnosis of IPAS.
  • Our experience supports the view that endoscopic ultrasound-guided fine-needle aspiration may enable a reliable, preoperative diagnosis of IPAS and thus prevent unnecessary surgery.
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / ultrasonography. Aged. Animals. Carcinoma, Acinar Cell / pathology. Carcinoma, Acinar Cell / ultrasonography. Coloring Agents. Diagnosis, Differential. Humans. Inflammation / pathology. Inflammation / ultrasonography. Lymphocytes / pathology. Lymphocytes / ultrasonography. Male. Pancreas / anatomy & histology. Pancreas / ultrasonography

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  • (PMID = 20923303.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Coloring Agents
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78. Heinrich S, Goerres GW, Schäfer M, Sagmeister M, Bauerfeind P, Pestalozzi BC, Hany TF, von Schulthess GK, Clavien PA: Positron emission tomography/computed tomography influences on the management of resectable pancreatic cancer and its cost-effectiveness. Ann Surg; 2005 Aug;242(2):235-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fifty-one patients had lesions in the head and 8 in the tail of the pancreas.
  • [MeSH-major] Adenocarcinoma / diagnosis. Pancreatic Neoplasms / diagnosis. Positron-Emission Tomography. Tomography, X-Ray Computed

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  • (PMID = 16041214.001).
  • [ISSN] 0003-4932
  • [Journal-full-title] Annals of surgery
  • [ISO-abbreviation] Ann. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Other-IDs] NLM/ PMC1357729
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79. Hayashi N, Soma I, Nakano K, Higaki N, Murakami M, Hayashida H, Kan K, Ichihara T, Sakon M: [Repeated resections of asynchronous liver metastases after pancreatomy for pancreatic cancer--a case report]. Gan To Kagaku Ryoho; 2009 Nov;36(12):2410-2
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

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  • A 71-year-old woman was referred to our hospital for a local recurrence in the tail of the pancreas in October 2006, 17 months after the first distal pancreatectomy.
  • The histopathological findings of each specimen from the resected liver showed tubular adenocarcinoma, same as the original pancreatic tumor obtained from the first surgery.
  • [MeSH-major] Adenocarcinoma / pathology. Hepatectomy. Liver Neoplasms / secondary. Liver Neoplasms / surgery. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / surgery

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  • (PMID = 20037439.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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80. Ichimura T, Kondo S, Okamura K, Tanaka E, Hirano S: Total parenchymal pancreatectomy preserving the duodenum, choledochus and spleen for widespread intraductal papillary mucinous neoplasm: report of a case. Hepatogastroenterology; 2010 Jan-Feb;57(97):8-11
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

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  • For patients with benign or low malignant diseases of the pancreas, several organ-preserving surgical techniques of pancreatectomy have been presented for localized lesions.
  • In cases of widespread or multifocal neoplasms of the pancreas, however, it is difficult to treat with this limited pancreatectomy because of a possible risk of residual dysplastic foci.
  • A papillary tumor was located in the body of the pancreas, and intraepithelial spreading reached almost the end of the pancreas tail and nearly over the midpoint of the pancreas head.
  • We performed total parenchymal pancreatectomy, an initial surgical procedure in which almost all parenchyma of the pancreas was resected but the duodenum, the common bile duct and the spleen were preserved and no reconstruction was needed.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Pancreatectomy. Pancreatic Neoplasms / surgery

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  • (PMID = 20422863.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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81. Han FH, Zhan WH, Li YM, He YL, Peng JS, Ma JP, Wang Z, Chen ZX, Zheng ZQ, Wang JP, Huang YH, Dong WG: [Analysis of long-term results of radical gastrectomy combining splenectomy for gastric cancer]. Zhonghua Wai Ke Za Zhi; 2005 Sep 1;43(17):1114-7
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  • It was significantly different between gastric adenocarcinoma in proximal and body of stomach and that in distal stomach, poor differentiation and adenocarcinoma anaplastic and well and moderately differentiation adenocarcinoma, Borrmann III and IV types and Borrmann I and II types, infiltrated depth in T(3) and T(4) and infiltrated depth in T(1) and T(2), clinical stages III and IV and clinical stages I and II.
  • CONCLUSIONS: Spleen should be reserved for patients with gastric cancer at stage I and II, and radical excision combining splenectomy could only be performed at stage III and IV patients with cancer infiltrating body and tail of the pancreas, or lymph nodes metastasis in the splenic hilus.

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  • (PMID = 16194307.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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82. Kluijt I, Cats A, Fockens P, Nio Y, Gouma DJ, Bruno MJ: Atypical familial presentation of FAMMM syndrome with a high incidence of pancreatic cancer: case finding of asymptomatic individuals by EUS surveillance. J Clin Gastroenterol; 2009 Oct;43(9):853-7
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  • In selected individuals at high risk of developing PC, surveillance of the pancreas might be able to detect premalignant lesions and early invasive cancers, and probably improve survival.
  • In a mother and a daughter, mass lesions were found by EUS in the tail and body of the pancreas.
  • [MeSH-major] Adenocarcinoma / ultrasonography. Adenocarcinoma, Mucinous / ultrasonography. Dysplastic Nevus Syndrome / ultrasonography. Endosonography. Mass Screening / methods. Pancreatic Neoplasms / ultrasonography

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  • [CommentIn] J Clin Gastroenterol. 2009 Oct;43(9):797-802 [19652621.001]
  • (PMID = 19417680.001).
  • [ISSN] 1539-2031
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p16
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83. Ionescu M, Dumitraşcu T, Stroescu C, Ciurea S, Popescu I: [Resection of the celiac axis increase resectability rate in locally advanced pancreatic body and gastric tumor]. Chirurgia (Bucur); 2006 May-Jun;101(3):297-305
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  • Carcinoma of the body and tail of the pancreas is often diagnosed at an advanced stage or metastatic stage.
  • [MeSH-major] Adenocarcinoma / surgery. Celiac Artery / surgery. Pancreatic Neoplasms / surgery. Stomach Neoplasms / surgery

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  • (PMID = 16927919.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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84. Okamoto Y, Maeba T, Kakinoki K, Okano K, Izuishi K, Wakabayashi H, Usuki H, Suzuki Y: A patient with unresectable advanced pancreatic cancer achieving long-term survival with gemcitabine chemotherapy. World J Gastroenterol; 2008 Nov 28;14(44):6876-80
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

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  • Abdominal computed tomography (CT) and endoscopic retrograde cholangio-pancreatography (ERCP) revealed that the density of the entire pancreas had decreased, and showed dilatation of the common bile duct (CBD) and the main pancreatic duct (MPD).
  • The entire pancreas was a hard mass, and a needle biopsy was obtained from the head, body and tail of the pancreas.
  • These biopsies diagnosed a poorly differentiated adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antimetabolites, Antineoplastic / administration & dosage. Deoxycytidine / analogs & derivatives. Pancreatic Neoplasms / drug therapy

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  • (PMID = 19058319.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
  • [Other-IDs] NLM/ PMC4988355
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85. Hadjicostas P, Malakounides N, Varianos C, Kitiris E, Lerni F, Symeonides P: Radiofrequency ablation in pancreatic cancer. HPB (Oxford); 2006;8(1):61-4
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  • The radiofrequency destruction of solid pancreatic tumors sounds logical but also seems risky due to the friable pancreatic parenchyma, the fear of pancreatitis and the prejudiced myth of 'the pancreas is not your friend'.
  • PATIENTS AND METHODS: We present our initial experience and we describe our technique during intraoperative RFA in four patients with locally advanced and unresectable pancreatic adenocarcinoma (head of pancreas, three; body-tail, one; diameter, 3-12 cm).
  • In one patient (with cancer of the body of the pancreas) who was receiving morphine because of intolerable pain, significant pain relief has been observed.

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  • (PMID = 18333241.001).
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  • [Journal-full-title] HPB : the official journal of the International Hepato Pancreato Biliary Association
  • [ISO-abbreviation] HPB (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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86. Chen YJ, Cheng YD, Liu HY, Lin PY, Wang CS: Observation of biochemical imaging changes in human pancreatic cancer tissue using Fourier-transform infrared microspectroscopy. Chang Gung Med J; 2006 Sep-Oct;29(5):518-27
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

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  • Tissue samples were obtained immediately after resection in a patient who underwent a distal pancreatectomy including the pancreatic body and tail.
  • The analytical results indicate that these FT-IR microspectroscopic biochemical images reflect the distribution of cell components, which could be correlated with stained tissue in adenocarcinoma in pancreatic tissues.
  • This study with samples of noncancerous and cancerous pancreatic tissues has clearly demonstrated that FT-IR microspectroscopy using the mapping method can be used for diagnosis.
  • [MeSH-minor] DNA, Neoplasm / analysis. Female. Humans. Lipids / analysis. Middle Aged. Neoplasm Proteins / analysis. Pancreas / chemistry. Pancreas / pathology. Protein Conformation

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  • (PMID = 17214398.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Lipids; 0 / Neoplasm Proteins
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87. Liu RC, Traverso LW: Diagnostic laparoscopy improves staging of pancreatic cancer deemed locally unresectable by computed tomography. Surg Endosc; 2005 May;19(5):638-42
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

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  • METHODS: Between April 2000 and February 2004, 74 patients with locally unresectable pancreatic cancer and no evidence of metastasis detected by high-quality pancreas protocol computed tomography underwent outpatient staging laparoscopy and peritoneal lavage cytology.
  • Body and tail tumors were twice as likely as pancreatic head tumors to have unsuspected metastasis (53% vs 28%).
  • [MeSH-major] Adenocarcinoma / secondary. Laparoscopy / statistics & numerical data. Liver Neoplasms / secondary. Neoplasm Staging / methods. Pancreatic Neoplasms / pathology. Peritoneal Neoplasms / secondary

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  • (PMID = 15776215.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Germany
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88. Okamoto N, Inaba K, Konno H: [Continuous treatment with S-1, an effective strategy for an older adult with unresectable advanced pancreatic cancer with peritoneal dissemination-a case report]. Gan To Kagaku Ryoho; 2009 Jul;36(7):1187-9
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

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  • CT scanning showed severe ascites and a low-density area 2 cm wide at the tail of the pancreas.
  • Ascitic cytology revealed adenocarcinoma and carcinomatous peritonitis due to pancreatic cancer.
  • Six months later CT scanning showed that the ascites had disappeared and that the low-density area at the tail of the pancreas had become less obvious.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antimetabolites, Antineoplastic / therapeutic use. Oxonic Acid / therapeutic use. Pancreatic Neoplasms / drug therapy. Tegafur / therapeutic use

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  • (PMID = 19620815.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid
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89. King J, Kazanjian K, Matsumoto J, Reber HA, Yeh MW, Hines OJ, Eibl G: Distal pancreatectomy: incidence of postoperative diabetes. J Gastrointest Surg; 2008 Sep;12(9):1548-53
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  • INTRODUCTION: Distal pancreatectomy is an accepted and safe procedure for lesions of the body and tail of the pancreas.
  • RESULTS: Of these 125 patients, 27 (21.6%) had an islet cell tumor, 25 (20%) adenocarcinoma, 24 (18.4%) serous cystic neoplasm, 19 (15.2%) mucinous cystic neoplasm, 11 (8.8%) chronic pancreatitis, and eight (6.4%) intraductal papillary mucinous neoplasm.
  • Neither demographics, diagnosis, nor operative statistics impacted the risk of postoperative diabetes.
  • [MeSH-minor] Age Distribution. Aged. Analysis of Variance. Blood Glucose / analysis. Cohort Studies. Female. Follow-Up Studies. Humans. Incidence. Laparoscopy / adverse effects. Laparoscopy / methods. Length of Stay. Male. Middle Aged. Pancreatic Neoplasms / diagnosis. Pancreatic Neoplasms / mortality. Pancreatic Neoplasms / surgery. Postoperative Complications / diagnosis. Postoperative Complications / epidemiology. Probability. Reference Values. Registries. Retrospective Studies. Risk Assessment. Severity of Illness Index. Sex Distribution. Survival Analysis

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  • (PMID = 18543045.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Grant] United States / NCCIH NIH HHS / AT / P01 AT003960; United States / NCI NIH HHS / CA / R21 CA124609
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose
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90. Albores-Saavedra J, Wu J, Crook T, Amirkhan RH, Jones L, Hruban RH: Intestinal and oncocytic variants of pancreatic intraepithelial neoplasia. A morphological and immunohistochemical study. Ann Diagn Pathol; 2005 Apr;9(2):69-76
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The first variant with an intestinal phenotype was associated with mucinous carcinomas that occurred in the tail of the pancreas of 2 men (60 and 65 years old).
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma in Situ / pathology. Intestines / pathology. Oxyphil Cells / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 15806512.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 62924
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MUC2 protein, human; 0 / Mucin-1; 0 / Mucin-2; 0 / Mucins
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91. Hutchinson CB, Canlas K, Evans JA, Obando JV, Waugh M: Endoscopic ultrasound-guided fine needle aspiration biopsy of the intrapancreatic accessory spleen: a report of 2 cases. Acta Cytol; 2010 May-Jun;54(3):337-40
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  • CASES: Each patient underwent computed tomographic evaluation for abdominal pain; it revealed a mass or thickening within the tail of the pancreas.
  • Definitive tissue diagnosis in these 2 cases avoided not only unnecessary surgical intervention but also the need for consideration of a "watch and wait" strategy with further imaging and possible additional biopsy attempts.
  • [MeSH-major] Choristoma / diagnosis. Pancreatic Diseases / diagnosis. Spleen
  • [MeSH-minor] Adenocarcinoma / diagnosis. Antigens, CD / metabolism. Biomarkers / metabolism. Biopsy, Fine-Needle. Diagnosis, Differential. Endocrine Gland Neoplasms / diagnosis. Endosonography. Female. Humans. Male. Middle Aged. Pancreatic Neoplasms / diagnosis

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  • (PMID = 20518423.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers
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92. Yildirim Y, Sanci M: The feasibility and morbidity of distal pancreatectomy in extensive cytoreductive surgery for advanced epithelial ovarian cancer. Arch Gynecol Obstet; 2005 Jun;272(1):31-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The objective of this study is to evaluate the feasibility and morbidity of pancreatic resection as a component of extensive cytoreductive surgery in epithelial ovarian cancer (EOC) patients with pancreas metastasis.
  • Six (6.12%) of these patients had pancreatic tail metastasis and were operated on using the distal pancreatectomy.
  • RESULTS: Preoperatively, only 1 (16.7%) of the 6 patients had signs of metastasis to the pancreas on computed tomography (CT).
  • CONCLUSION: In conclusion, if optimal cytoreduction is foreseen in advanced epithelial ovarian cancer with pancreatic tail metastasis, distal pancreatectomy should be kept in mind.
  • [MeSH-major] Adenocarcinoma / surgery. Ovarian Neoplasms / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery


93. Matsubayashi H, Matsunaga K, Uesaka K, Fukutomi A, Sasaki K, Furukawa H, Ono H: A case of pancreatic carcinoma with suspected autoimmune pancreatitis. Clin J Gastroenterol; 2009 Feb;2(1):59-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ultrasonography demonstrated an enlarged pancreas with smooth borders and low internal echo density.
  • Enhanced computed tomography (CT) showed a sausage-shaped pancreas without definitive metastasis to the surrounding lymph nodes and liver.
  • Imaging of the pancreatic duct, including endoscopic retrograde pancreatography (ERP) and magnetic resonance cholangiopancreatography (MRCP), showed stenosis of the main pancreatic duct at the pancreatic head as well as a long segment of narrowing at the body and no dilatation at the tail.
  • Tissues from these stenotic sites and open biopsy from pancreatic body showed infiltrating adenocarcinoma and dense fibrosis.
  • It is important to confirm diagnosis with histology in cases of suspicious autoimmune pancreatitis, even when the clinical images are compatible with AIP.

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  • (PMID = 26191812.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Auto-antibody / Autoimmune pancreatitis / IgG4 / Pancreatic carcinoma
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94. Seelig SK, Burkert B, Chromik AM, Tannapfel A, Uhl W, Seelig MH: Pancreatic resections for advanced M1-pancreatic carcinoma: the value of synchronous metastasectomy. HPB Surg; 2010;2010:579672
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: From January 1, 2004 to December, 2007 a total of 20 patients with pancreatic malignancies were retrospectively evaluated who underwent pancreatic surgery with synchronous resection of hepatic, adjacent organ, or peritoneal metastases for proven UICC stage IV periampullary cancer of the pancreas.
  • The primary tumor was located in the pancreatic head (n = 9, 45%), in pancreatic tail (n = 9, 45%), and in the papilla Vateri (n = 2, 10%).
  • Median postoperative survival was 10.7 months (2.6-37.7 months) which was not significantly different from a matched-pair group of patients who underwent pancreatic resection for UICC adenocarcinoma of the pancreas (median survival 15.6 months; P = .1).
  • CONCLUSION: Pancreatic resection for M1 periampullary cancer of the pancreas can be performed safely in well-selected patients.

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  • (PMID = 21197481.001).
  • [ISSN] 1607-8462
  • [Journal-full-title] HPB surgery : a world journal of hepatic, pancreatic and biliary surgery
  • [ISO-abbreviation] HPB Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3010622
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95. Ikeda E, Shigematsu T, Hidaka K, Nishikawa A, Katayama M, Okajima T, Kawahara T, Tanaka M, Banba M: [A case of adenosquamous gastric carcinoma successfully treated with TS-1, low-dose CDDP and docetaxel as neoadjuvant chemotherapy]. Gan To Kagaku Ryoho; 2007 Mar;34(3):423-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient was a 66-year-old male with extremely advanced gastric cancer type 3 and diagnosed with adenocarcinoma by endoscopic biopsies specimens.
  • Therefore, total gastrectomy, partial pancreas body and tail resection, and D 2 lymph node dissection were performed.

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  • (PMID = 17353635.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 0 / Taxoids; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 15H5577CQD / docetaxel; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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96. Bergenfeldt M, Moesgaard F, Burcharth F: Curative resection for left-sided pancreatic malignancy. HPB (Oxford); 2006;8(3):211-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Reports on the management of tumours of the body and tail have been less frequent.
  • Current knowledge teaches that adenocarcinomas of the body and tail of the pancreas have a worse prognosis.
  • The patients with ductal adenocarcinoma had a median survival of 14 months and a 5-year survival of 17%.
  • One patient with malignant insulinoma and two patients with adenocarcinoma had a survival exceeding 5 years (98, 174 and 183 months, respectively).
  • DISCUSSION: Selected patients with left-sided pancreatic adenocarcinoma may be operated on with results similar to pancreaticoduodenectomy (Whipple procedure) for cancer of the pancreatic head regarding postoperative morbidity and mortality as well as long-term survival.

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  • (PMID = 18333279.001).
  • [ISSN] 1365-182X
  • [Journal-full-title] HPB : the official journal of the International Hepato Pancreato Biliary Association
  • [ISO-abbreviation] HPB (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2131678
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97. Zucchini G, Pezzilli R, Ricci C, Casadei R, Santini D, Calculli L, Corinaldesi R: A bizarre abdominal cystic lesion. JOP; 2010;11(5):480-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the case reported, a retained gauze leaved during a surgical approach for removing a solid-cystic papillary tumor localized in the pancreatic tail, caused both persistent abdominal discomfort and the presence of an abdominal cystic lesion at imaging techniques.
  • When a previous operative history is present, a foreign body should be taken into account in the differential diagnosis of a patient with an intra-abdominal cystic mass.
  • Finally, radio-opaque marker should be routinely used by surgeons in order to reach a correct diagnosis in operated patients having retained gauze.
  • [MeSH-minor] Abdomen / surgery. Adenocarcinoma, Papillary / surgery. Adult. Diagnosis, Differential. Female. Foreign Bodies / diagnosis. Foreign Bodies / surgery. Humans. Pancreatic Neoplasms / surgery. Postoperative Complications / etiology. Radiography, Abdominal

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  • (PMID = 20818122.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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98. Artinyan A, Soriano PA, Prendergast C, Low T, Ellenhorn JD, Kim J: The anatomic location of pancreatic cancer is a prognostic factor for survival. HPB (Oxford); 2008;10(5):371-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Pancreatic cancers of the body and tail (BT) appear to have poorer survival compared with head (HD) lesions.
  • METHODS: The Surveillance, Epidemiology, and End Results registry identified 33,752 patients with pancreatic adenocarcinoma and 6443 patients who underwent cancer-directed surgery between 1988 and 2004.

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  • (PMID = 18982154.001).
  • [ISSN] 1365-182X
  • [Journal-full-title] HPB : the official journal of the International Hepato Pancreato Biliary Association
  • [ISO-abbreviation] HPB (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2575681
  • [Keywords] NOTNLM ; SEER / pancreatic cancer / tumor location
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99. Plaza JA, Colonna J, Vitellas KM, Frankel WL: Lymphoplasmacytic sclerosing pancreatitis. Ann Diagn Pathol; 2005 Oct;9(5):298-301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • An abdominal magnetic resonance image showed thickening of the pancreatic tail and compression of the pancreatic duct.
  • Grossly, the pancreas contained a yellowish white, firm homogeneous mass measuring 6.5 x 3.3 x 2.9 cm involving the entire pancreatic tail and hilum of the spleen.
  • [MeSH-major] Adenocarcinoma / pathology. Autoimmune Diseases / pathology. Pancreatic Neoplasms / pathology. Pancreatitis / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged


100. Zou YP, Li WM, Zheng F, Li FC, Huang H, Du JD, Liu HR: Intraoperative radiofrequency ablation combined with 125 iodine seed implantation for unresectable pancreatic cancer. World J Gastroenterol; 2010 Oct 28;16(40):5104-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The tumor, 4-12 cm in diameter, located in pancreatic head of 23 patients and in pancreatic body and tail of 9 patients, was found to be unresectable during operation.
  • Diagnosis of pancreatic cancer was made through intraoperative biopsy.
  • [MeSH-major] Adenocarcinoma / therapy. Catheter Ablation / methods. Iodine Radioisotopes / therapeutic use. Pancreatic Neoplasms / therapy. Radiotherapy / methods

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  • (PMID = 20976848.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Iodine Radioisotopes
  • [Other-IDs] NLM/ PMC2965288
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