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1. Kanitakis J, Chouvet B: Granular-cell basal cell carcinoma of the skin. Eur J Dermatol; 2005 Jul-Aug;15(4):301-3
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  • [Title] Granular-cell basal cell carcinoma of the skin.
  • [MeSH-major] Adenocarcinoma / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Immunohistochemistry. Male

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  • (PMID = 16048765.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 12
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2. Agrawal A, Yau A, Magliocco A, Chu P: Cutaneous metastatic disease in cervical cancer: a case report. J Obstet Gynaecol Can; 2010 May;32(5):467-472
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  • BACKGROUND: Cervical cancer metastasizes to skin in < 2% of patients.
  • CASE: A 66-year-old postmenopausal woman with a diagnosis of stage IVa cervical carcinoma was treated with radical concurrent chemotherapy and radiation.
  • Two months after completing treatment, the patient noted maculopapular skin lesions in the lower abdomen.
  • In the majority of these cases, patients presented within 10 years of initial diagnosis and died within a mean of 8.5 months from cutaneous metastasis.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / secondary. Skin Neoplasms / secondary. Uterine Cervical Neoplasms / pathology


3. Niikura H, Yoshida H, Ito K, Takano T, Watanabe H, Aiba S, Yaegashi N: Paget's disease of the vulva: clinicopathologic study of type 1 cases treated at a single institution. Int J Gynecol Cancer; 2006 May-Jun;16(3):1212-5
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  • Medical records were reviewed for pathologic diagnosis, patient age, associated neoplasms, type(s) of eczema, symptom duration, treatment, surgical procedures, recurrence, and length of follow-up.
  • Type 1a (intraepithelial) Paget's disease accounted for 18 patients, with 3 type 1b (invasive) cases and 1 type 1c (intraepithelial disease with underlying adenocarcinoma) case.
  • Mapping biopsy with careful examination of characteristic skin surface may be useful for surgery of type 1a cases.
  • Inguinal lymphadenectomy is recommended in cases with question of invasion or known underlying adenocarcinoma.
  • [MeSH-major] Paget Disease, Extramammary / diagnosis. Vulva. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Aged. Aged, 80 and over. Carcinoma in Situ / diagnosis. Fatal Outcome. Female. Humans. Middle Aged. Neoplasm Invasiveness / diagnosis. Neoplasm Staging. Neoplasms, Multiple Primary / diagnosis

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  • (PMID = 16803508.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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4. Warchoł R, Szymański L, Seichter A: [Rectal adenocarcinoma metastasis to the facial skin--case report]. Otolaryngol Pol; 2008;62(1):96-9
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  • [Title] [Rectal adenocarcinoma metastasis to the facial skin--case report].
  • Histopatological examination of specimen from the facial skin lesion revealed adenocarcinoma cells.
  • RESULTS AND CONCLUSIONS: We present this case report as an example of an unusual and rare secondary malignancy of head and neck, emphasizing the interdisciplinary character of oncological treatment and the role of oncological vigilance on every step of diagnosis.
  • [MeSH-major] Adenocarcinoma / secondary. Facial Neoplasms / secondary. Rectal Neoplasms / pathology. Skin Neoplasms / secondary

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  • Hazardous Substances Data Bank. FLUOROURACIL .
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  • (PMID = 18637429.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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5. Manonukul J, Kajornvuthidej S: Sebaceous neoplasms in Siriraj Hospital, Mahidol University: a 9-year-retrospective study. J Med Assoc Thai; 2010 Aug;93(8):978-91
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  • All slides were re-analyzed and re-diagnosed, without knowledge of the previous diagnosis or any clinical data, according to the criteria described in the standard textbooks of dermatopathology by Elder, McKee.
  • In these instances, the clinical correlation was needed for positive diagnosis.
  • RESULTS: Two hundred seven sebaceous neoplasms (2.34%) from the 8819 skin biopsies that were taken in the Department of Pathology, Siriraj Hospital during the 9-year-period, were included After exclusion of some authentically non-sebaceous neoplasms, 182 sebaceous neoplasms were found Nevus sebaceus (n=85, 46.7%) and sebaceous hyperplasia (n=64, 35.1%) were the two most common benign lesions.
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Sebaceous Gland Neoplasms / pathology

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  • (PMID = 20718175.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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6. Young GS, Setayesh K: Spin-echo echo-planar perfusion MR imaging in the differential diagnosis of solitary enhancing brain lesions: distinguishing solitary metastases from primary glioma. AJNR Am J Neuroradiol; 2009 Mar;30(3):575-7
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  • [Title] Spin-echo echo-planar perfusion MR imaging in the differential diagnosis of solitary enhancing brain lesions: distinguishing solitary metastases from primary glioma.
  • [MeSH-minor] Adenocarcinoma / secondary. Adult. Aged. Astrocytoma / pathology. Breast Neoplasms / pathology. Carcinoma, Basal Cell / secondary. Colorectal Neoplasms / pathology. Diagnosis, Differential. Esophageal Neoplasms / pathology. Female. Humans. Lung Neoplasms / pathology. Male. Melanoma / secondary. Middle Aged. Models, Neurological. Prostatic Neoplasms / pathology. Retrospective Studies. Sensitivity and Specificity. Skin Neoplasms / pathology

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  • (PMID = 19095787.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article; Technical Report
  • [Publication-country] United States
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7. Cribier B: [Accurate diagnosis of adnexal tumours can be a matter of life or death]. Ann Dermatol Venereol; 2009 Feb;136(2):125-32
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  • [Title] [Accurate diagnosis of adnexal tumours can be a matter of life or death].
  • [MeSH-major] Neoplasms, Adnexal and Skin Appendage / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma, Sebaceous / pathology. Diagnosis, Differential. Hamartoma Syndrome, Multiple / pathology. Humans. Male. Melanoma / pathology. Pilomatrixoma / pathology. Sebaceous Gland Neoplasms / pathology

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  • (PMID = 19232249.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 58
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8. Azmandian J, Lessan-Pezeshki M, Alipour Abedi B, Mahdavi-Mazdeh M, Nafar M, Farhangi S: Posttransplant malignancies and their relationship with human leukocyte antigens in kidney allograft recipients. Iran J Kidney Dis; 2007 Oct;1(2):98-101
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  • INTRODUCTION: Kidney transplant recipients are at increased risk of cancers, most frequently skin cancers, and in some regions, Kaposi sarcoma and non-Hodgkin lymphoma.
  • RESULTS: There were 15 patients (34.1%) with Kaposi sarcoma; 13 (29.6%) with non-Hodgkin lymphoma, 6 (13.6%) with skin cancer, 2 (4.5%) with ovary cyst adenocarcinoma, and 8 (18.2%) with other tumors.
  • The mean interval from transplantation to diagnosis of malignancy was 15.3 month.

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  • (PMID = 19363276.001).
  • [ISSN] 1735-8582
  • [Journal-full-title] Iranian journal of kidney diseases
  • [ISO-abbreviation] Iran J Kidney Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Chemical-registry-number] 0 / HLA-C Antigens; 0 / HLA-C*04 antigen
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9. Hounkpati A, Marie I, Paillotin D, Muir JF, Cuvelier A: [Paraneoplastic sclerodermiform syndrome]. Rev Mal Respir; 2010 Mar;27(3):251-6
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  • A diagnosis of bronchial adenocarcinoma was made following mediastinoscopy and the patient was treated with neo-adjuvant chemotherapy and lobectomy.
  • After two cycles of treatment, his skin lesions had almost disappeared.
  • In this case report, the skin lesions disappeared quickly after antineoplastic treatment.
  • [MeSH-major] Adenocarcinoma / complications. Lung Neoplasms / complications. Paraneoplastic Syndromes / etiology. Scleroderma, Systemic / etiology

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  • [Copyright] Copyright 2010 SPLF. Published by Elsevier Masson SAS. All rights reserved.
  • (PMID = 20359618.001).
  • [ISSN] 1776-2588
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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10. Martínez-Luna E, Puebla-Miranda M, Vega-Memije ME: [Skin metastasis of gastric adenocarcinoma. Case report]. Rev Gastroenterol Mex; 2009 Oct-Dec;74(4):362-5
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  • [Title] [Skin metastasis of gastric adenocarcinoma. Case report].
  • [Transliterated title] Metástasis cutáneas de adenocarcinoma gástrico; informe de un caso.
  • These lesions generally occur in late stages of disease, being uncommon their presentation at the time of diagnosis.
  • We inform the case of a male patient who presented a metastatic adenocarcinoma in the skin of the chest.
  • Under the suspect of primary tumor in the gastrointestinal tract, an upper gastrointestinal endoscopy was made corroborating diagnosis of a primary gastric cancer.
  • The case instructs the unusual morphology of cutaneous metastasis of gastric adenocarcinoma, as well appearing as the initial clinical data in an extended malignant disease.
  • Key words: cutaneous metastases, metastatic adenocarcinoma, gastric carcinoma, Mexico.
  • [MeSH-major] Adenocarcinoma / secondary. Skin Neoplasms / secondary. Stomach Neoplasms / pathology

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  • (PMID = 20423769.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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11. Elgoweini M, May C, Devgun MS, Howatson SR, Gupta G: Secondary cryofibrinogenaemia due to bronchial adenocarcinoma presenting as cutaneous necrosis. Clin Exp Dermatol; 2007 May;32(3):343-4
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  • [Title] Secondary cryofibrinogenaemia due to bronchial adenocarcinoma presenting as cutaneous necrosis.
  • [MeSH-major] Adenocarcinoma, Bronchiolo-Alveolar / complications. Cryoglobulinemia / etiology. Fibrinogens, Abnormal. Lung Neoplasms / complications. Skin / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Necrosis

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  • (PMID = 17397363.001).
  • [ISSN] 0307-6938
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Fibrinogens, Abnormal
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12. Ilha MR, Loretti AP, Barros CS, Gimeno EJ, Martin CA: Papillary adenocarcinoma of the extrahepatic bile duct in a Holstein cow. Vet Pathol; 2005 Jan;42(1):74-7
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  • [Title] Papillary adenocarcinoma of the extrahepatic bile duct in a Holstein cow.
  • Abnormal physical examination findings included poor body condition, dehydration, icterus, and photodermatitis on nonpigmented areas of the skin of the dorsum.
  • The diagnosis of papillary adenocarcinoma of the extrahepatic bile duct was based on the morphologic features of the neoplasm and evidence of local invasion.
  • [MeSH-major] Adenocarcinoma, Papillary / veterinary. Bile Duct Neoplasms / veterinary. Bile Ducts, Extrahepatic / pathology. Cattle Diseases / pathology

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  • (PMID = 15657275.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Keratin-7; 68238-35-7 / Keratins
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13. Fusco D, Pasternack F, Ward K, Grossman M, O'Toole K, Saluja D, Luchsinger JA: A rare presentation of gastric adenocarcinoma. Am J Clin Oncol; 2009 Oct;32(5):541-2
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  • [Title] A rare presentation of gastric adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Pleural Effusion, Malignant / radiography. Skin Neoplasms / secondary. Stomach Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 23061096.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Kawabe Y: [Application and problems of quantiFERON TB-2G for tuberculosis control programs--(2) clinical use of quantiFERON TB-2G]. Kekkaku; 2007 Jan;82(1):61-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: This article describe the usefulness and remarks in clinical use on diagnosis and system for detection of tuberculosis infection among staff in NHO Tokyo Hospital that has 100 beds for tuberculosis. METHOD:.
  • Tuberculin skin testing and baseline QFT were done for 92 staff on April 2006, 2 were shifted to tuberculosis ward from non-tuberculosis ward and 90 were new employee. RESULT:.
  • A case with small nodule on CT with QFT positive was adenocarcinoma. (2) Tuberculin Skin Testing and baseline QFT for 92 staff, 4 were QFT positive.
  • Compared with Tuberculin Skin Testing more than 29 mm in erythema, QFT positive rate was 9% and more than 9 mm in induration, QFT positive rate was 7%.
  • CONCLUSION: Although QFT is a very excellent tool for detecting tuberculosis infection, on clinical diagnosis, it is important to mind that QFT depends on clinical condition especially immunosuppressive diseases, aging and past infection.
  • This is a useful assistant tool on clinical diagnosis.
  • [MeSH-major] Antigens, Bacterial / immunology. Interferon-gamma / blood. Mycobacterium avium Complex / immunology. Mycobacterium avium-intracellulare Infection / diagnosis. Mycobacterium tuberculosis / immunology. Tuberculosis / diagnosis. Tuberculosis / prevention & control
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adult. Aged. Contact Tracing. Disease Outbreaks. Female. Humans. Lung Neoplasms / diagnosis. Male. Middle Aged. Tuberculin Test. Tuberculosis, Pulmonary / diagnosis. Tuberculosis, Pulmonary / prevention & control


15. Breiting LB, Christensen L, Dahlstrøm K, Winther JF, Breiting VB, Kalialis LV: [Primary mucinous carcinoma of the skin--a literature review]. Ugeskr Laeger; 2008 Oct 20;170(43):3399-402
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  • [Title] [Primary mucinous carcinoma of the skin--a literature review].
  • Primary mucinous carcinoma of the skin (PKMK) is a rare malignant tumour of the sweat glands.
  • [MeSH-major] Adenocarcinoma, Mucinous. Skin Neoplasms
  • [MeSH-minor] Diagnosis, Differential. Humans. Neoplasm Recurrence, Local. Prognosis. Sweat Gland Neoplasms / diagnosis. Sweat Gland Neoplasms / pathology. Sweat Gland Neoplasms / surgery

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  • (PMID = 18976593.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 40
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16. Levrat E, Waeber G: [Systemic sclerosis and cancer]. Praxis (Bern 1994); 2006 Jun 14;95(24):983-8
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  • The combination of skin induration with clinical features such as dyspnea, facial telangiectasia, digital infarctions and/or dysphagia supports the diagnosis of systemic sclerosis.
  • The oesophageal dysmotility is associated with symptoms which may delay the diagnosis of gastro-oesophageal cancer.
  • Unfortunately, these symptoms delayed the diagnosis of gastric adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Esophageal Neoplasms / diagnosis. Esophagogastric Junction. Paraneoplastic Syndromes / diagnosis. Scleroderma, Systemic / diagnosis. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Esophageal Stenosis / diagnosis. Esophageal Stenosis / pathology. Esophagoscopy. Esophagus / pathology. Facial Dermatoses / diagnosis. Facial Dermatoses / pathology. Female. Hand Dermatoses / diagnosis. Hand Dermatoses / pathology. Humans. Scleroderma, Localized / diagnosis. Scleroderma, Localized / pathology. Stomach / pathology


17. Abbott JJ, Ahmed I: Adenocarcinoma of mammary-like glands of the vulva: Report of a case and review of the literature. Am J Dermatopathol; 2006 Apr;28(2):127-33
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  • [Title] Adenocarcinoma of mammary-like glands of the vulva: Report of a case and review of the literature.
  • Mammary-like glands are a poorly recognized structure of normal vulvar skin.
  • Excisional biopsy and Mohs micrographic surgery demonstrated an infiltrating adenocarcinoma of the mammary-like glands involving the dermis and subcutis.
  • On review of all 20 cases, the mean age at diagnosis was 59.6 years, the labia majora were involved in 13 cases (65%), and the mean lesional size was 2.5 cm.
  • Criteria for establishing the diagnosis of adenocarcinoma of mammary-like glands include identifying transition zones between normal mammary-like glands and adenocarcinomatous areas.
  • Use of aggressive surgical therapeutic regimens, particularly in the case of tumors localized to the skin, must be reassessed, especially given the likelihood of long-term morbidity with such regimens.
  • In our patient, successful Mohs micrographic surgery suggests that alternate management may be adopted for tumors localized to the skin, especially in elderly patients.
  • [MeSH-major] Adenocarcinoma / diagnosis. Vulvar Neoplasms / diagnosis

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  • (PMID = 16625074.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
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18. Serap D, Ozlem S, Melike Y, Alper D, Aynur A, Ata Türker A, Ardıç S: Acanthosis nigricans in a patient with lung cancer: a case report. Case Rep Med; 2010;2010
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  • Some skin lesions may accompany malignancies.
  • The result of the histopathologic examination of the endobronchial tissue biopsy was reported as non-small cell (adenocarcinoma) lung cancer.
  • Result of the histopathologic analysis of the punch biopsy of the skin lesions was reported as acanthosis nigricans .There are no pathognomonic dermatological findings for lung cancer.
  • In conclusion, there are skin lesions that accompany lung cancer and we believe that these should be considered for differential diagnosis.

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  • (PMID = 20811563.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Cabral ES, Cassarino DS: Desmoplastic tricholemmoma of the eyelid misdiagnosed as sebaceous carcinoma: a potential diagnostic pitfall. J Cutan Pathol; 2007 Dec;34 Suppl 1:22-5
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  • Therefore, DTL should enter the differential diagnosis of clear-cell neoplasms on the eyelid.
  • [MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Eyelid Neoplasms / diagnosis. Hair Diseases / diagnosis. Hair Follicle / pathology. Skin Neoplasms / diagnosis
  • [MeSH-minor] Antigens, CD34 / metabolism. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Glycogen / metabolism. Humans. Male. Middle Aged

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  • (PMID = 17997733.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 9005-79-2 / Glycogen
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20. Giordano G, Gnetti L, Ricci R, Merisio C, Melpignano M: Metastatic extragenital neoplasms to the uterus: a clinicopathologic study of four cases. Int J Gynecol Cancer; 2006 Jan-Feb;16 Suppl 1:433-8
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  • We considered the metastases in non-genital tract organs at diagnosis of primary neoplasm, the distribution of the metastases in the uterus, and the presence of concomitant metastases in other genital and non-genital tract organs.
  • The other two primary tumors were adenocarcinoma of the cecum and malignant melanoma of the skin.
  • The diagnosis was facilitated by clinical history, revealing the previous primary neoplasm, and by specific immunohistochemical study.
  • [MeSH-major] Adenocarcinoma / secondary. Breast Neoplasms / pathology. Cecal Neoplasms / pathology. Melanoma / secondary. Skin Neoplasms / pathology. Uterine Neoplasms / secondary
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Prognosis

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  • (PMID = 16515640.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Gil Martínez EM, Ramírez López MA, Moya García F, González Cabezas P, de la Riva Pérez P: [Early detection with FDG-PET of colonic tumors in patients with another known tumor]. Gastroenterol Hepatol; 2005 Jan;28(1):23-5
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  • Whole body FDG-PET is a highly useful technique in the early diagnosis of colorectal cancer, which in turn allows complete cure of patients with this disease.
  • [MeSH-minor] Adenocarcinoma / radionuclide imaging. Adenoma / radionuclide imaging. Aged. Early Diagnosis. Humans. Lung Neoplasms / radionuclide imaging. Male. Melanoma / radionuclide imaging. Middle Aged. Skin Neoplasms / radionuclide imaging

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  • (PMID = 15691465.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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22. Ivan D, Nash JW, Prieto VG, Calonje E, Lyle S, Diwan AH, Lazar AJ: Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin. J Cutan Pathol; 2007 Jun;34(6):474-80
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  • [Title] Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin.
  • p63, a recently identified homologue of the p53 gene, is mainly expressed by basal and myoepithelial cells in skin.
  • Others and we have shown the value of p63 in distinguishing primary adnexal tumors from visceral adenocarcinomas metastatic to skin.
  • We now investigate the pattern of p63 expression in metastases from skin adnexal carcinomas and their cognate primaries and evaluate p63 expression in a larger case series of malignant cutaneous adnexal neoplasms.
  • Twenty visceral metastatic adenocarcinomas to the skin and 7 primary mucinous carcinomas with cutaneous or visceral origin were compared.
  • Analysis of p63 expression may assist in the differential diagnosis of primary adnexal carcinomas versus metastatic visceral adenocarcinomas to the skin.
  • [MeSH-major] Adenocarcinoma, Mucinous / metabolism. Biomarkers, Tumor / metabolism. DNA-Binding Proteins / metabolism. Neoplasms, Adnexal and Skin Appendage / metabolism. Skin Neoplasms / metabolism. Trans-Activators / metabolism. Tumor Suppressor Proteins / metabolism
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Immunoenzyme Techniques. Retrospective Studies. Transcription Factors

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  • [CommentIn] J Cutan Pathol. 2008 Jul;35(7):692-3 [18312438.001]
  • (PMID = 17518775.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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23. Goncalves A, Fabbro M, Lhommé C, Gladieff L, Extra JM, Floquet A, Chaigneau L, Carrasco AT, Viens P: A phase II trial to evaluate gefitinib as second- or third-line treatment in patients with recurring locoregionally advanced or metastatic cervical cancer. Gynecol Oncol; 2008 Jan;108(1):42-6
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  • BACKGROUND: Cancer of the cervix occurs in approximately 500,000 women worldwide each year, with prognosis highly dependent on disease stage at diagnosis.
  • RESULTS: Thirty patients with squamous-cell carcinoma or adenocarcinoma were recruited from six centers in France.
  • Gefitinib was well tolerated, with the most common drug-related adverse events being skin and gastrointestinal toxicities.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Agents / therapeutic use. Carcinoma, Squamous Cell / drug therapy. Neoplasm Recurrence, Local / drug therapy. Quinazolines / therapeutic use. Uterine Cervical Neoplasms / drug therapy


24. Favrot C, Degorce-Rubiales F: Cutaneous metastases of a bronchial adenocarcinoma in a cat. Vet Dermatol; 2005 Jun;16(3):183-6
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  • [Title] Cutaneous metastases of a bronchial adenocarcinoma in a cat.
  • This case report describes a cat with metastasis of a bronchial adenocarcinoma to the abdominal skin.
  • The cat had been treated with antibiotics and corticosteroids for several episodes of coughing when it acutely developed erythema, pustules and plaques on the abdominal skin.
  • Diagnosis was based on cytological examination of fine-needle aspirates of cutaneous pustules, X-ray examination of the thorax and histological examination of skin biopsy samples.
  • Necropsy findings confirmed the diagnosis.
  • To the authors' knowledge, this is the first report of metastasis of a feline bronchial carcinoma to the ventral skin.
  • [MeSH-major] Adenocarcinoma / veterinary. Bronchial Neoplasms / veterinary. Cat Diseases / diagnosis. Skin Neoplasms / veterinary
  • [MeSH-minor] Abdomen. Animals. Cats. Dermatitis / etiology. Dermatitis / pathology. Dermatitis / veterinary. Diagnosis, Differential. Female

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  • (PMID = 15960632.001).
  • [ISSN] 0959-4493
  • [Journal-full-title] Veterinary dermatology
  • [ISO-abbreviation] Vet. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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25. Samaila MO: Adnexal skin tumors in Zaria, Nigeria. Ann Afr Med; 2008 Mar;7(1):6-10
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  • [Title] Adnexal skin tumors in Zaria, Nigeria.
  • BACKGROUND: Adnexal skin tumors share many features in common and differentiate along one line.
  • METHOD: A 16-year retrospective analysis of all adnexal skin tumors seen in a large University Teaching Hospital in Nigeria from January 1991- December 2006.
  • Only two cases had a clinical diagnosis of adnexal tumor.
  • CONCLUSION: Adnexal skin tumors have distinct histological patterns which differentiates them from other cutaneous tumors.
  • [MeSH-major] Carcinoma, Skin Appendage / classification. Neoplasms, Adnexal and Skin Appendage / classification
  • [MeSH-minor] Adenocarcinoma, Sebaceous / epidemiology. Adenocarcinoma, Sebaceous / pathology. Adenoma, Sweat Gland / epidemiology. Adenoma, Sweat Gland / pathology. Adolescent. Adult. Aged. Child. Child, Preschool. Female. Hair Follicle / pathology. Head and Neck Neoplasms / epidemiology. Head and Neck Neoplasms / pathology. Humans. Infant, Newborn. Male. Middle Aged. Nigeria / epidemiology. Retrospective Studies. Sebaceous Gland Neoplasms / epidemiology. Sebaceous Gland Neoplasms / pathology. Sweat Gland Neoplasms / epidemiology. Sweat Gland Neoplasms / pathology

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  • (PMID = 18702242.001).
  • [ISSN] 1596-3519
  • [Journal-full-title] Annals of African medicine
  • [ISO-abbreviation] Ann Afr Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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26. Martínez-Rodríguez R, Rodríguez-Escovar F, Bujons Tur A, Maroto P, Palou J, Villavicencio H: [Skin metastasis during follow-up of a clear cell renal carcinoma]. Arch Esp Urol; 2008 Jan-Feb;61(1):80-2
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  • [Title] [Skin metastasis during follow-up of a clear cell renal carcinoma].
  • Skin metastatic involvement by urological tumors is a rare clinical entity.
  • METHODS: We present the case of a 60-year-old male patient with the diagnosis of inferior maxillary skin metastasis 18 months after radical nephrectomy for clear cell adenocarcinoma.
  • Two years after diagnosis the patient is alive and a disease-free.
  • [MeSH-major] Carcinoma, Renal Cell / secondary. Kidney Neoplasms / pathology. Skin Neoplasms / secondary


27. Sprinzl MF, Schimanski CC, Moehler M, Schadmand-Fischer S, Galle PR, Kanzler S: Gemcitabine in combination with EGF-Receptor antibody (Cetuximab) as a treatment of cholangiocarcinoma: a case report. BMC Cancer; 2006;6:190
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  • Diagnosis was based on computed tomography, mini-laparoscopy and bioptic specimens.
  • Histology revealed an adenocarcinoma of the biliary tract with expression of epithelial growth factor receptor.
  • Cetuximab caused only mild skin toxicity (CTC, grade 1).
  • In parallel, Ca 19-9 serum levels, which were elevated 5-fold at time of diagnosis, returned to normal after 16 weeks of treatment.

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  • (PMID = 16846514.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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  • [Other-IDs] NLM/ PMC1564184
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28. Sayles M, Courtney E, Younis F, O'Donovan M, Ibrahim A, Fearnhead NS: Appendiceal mucinous adenocarcinoma presenting as an enterocutaneous fistula in an incisional hernia. BMJ Case Rep; 2010;2010
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  • [Title] Appendiceal mucinous adenocarcinoma presenting as an enterocutaneous fistula in an incisional hernia.
  • Histological evaluation confirmed a well-to-moderately differentiated mucinous adenocarcinoma arising on a background of dysplastic villous adenoma.
  • Tumour extended along the fistula track to involve the surface skin.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Appendiceal Neoplasms / diagnosis. Bone Transplantation. Hernia, Abdominal / diagnosis. Ilium / surgery. Intestinal Fistula / diagnosis. Postoperative Complications / diagnosis. Tissue and Organ Harvesting
  • [MeSH-minor] Abdominal Abscess / diagnosis. Aged. Appendectomy. Colectomy. Female. Humans. Laparoscopy. Lymph Node Excision. Neoplasm Staging. Reoperation

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  • (PMID = 22789695.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3038038
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29. Iftikhar I, Abdelmannan D, Daw HA: Dermatomyositis and esophageal cancer. South Med J; 2006 Jul;99(7):777-9
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  • CASE REPORT: A 58-year-old male recently diagnosed with esophageal cancer was admitted to the hospital with complaints of progressive dysphagia, generalized muscle weakness and skin rash.
  • He also developed a characteristic skin rash on the eyelids, the upper chest and around the nails that was thought to be most indicative of dermatomyositis.
  • In the setting of an underlying malignancy, these symptoms can be misleading and one can miss the diagnosis of dermatomyositis.
  • However, recognition of the characteristic skin rash may provide a clue to the diagnosis.
  • [MeSH-major] Adenocarcinoma / complications. Dermatomyositis / complications. Esophageal Neoplasms / complications


30. Breiting L, Dahlstrøm K, Christensen L, Winther JF, Breiting V: Primary mucinous carcinoma of the skin. Am J Dermatopathol; 2007 Dec;29(6):595-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mucinous carcinoma of the skin.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Breast Neoplasms / diagnosis. Breast Neoplasms / secondary. Diagnosis, Differential. Female. Humans. Scalp

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  • [CommentIn] Am J Dermatopathol. 2008 Oct;30(5):510 [18806504.001]
  • (PMID = 18032965.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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31. Akinci M, Salan A, Cetin B, Aslan S: Primary mucinous eccrine adenocarcinoma of the skin in a 69-year-old man. Chirurgia (Bucur); 2010 Jan-Feb;105(1):109-11
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  • [Title] Primary mucinous eccrine adenocarcinoma of the skin in a 69-year-old man.
  • The authors report a rare case of primary mucinous eccrine adenocarcinoma of the skin initially diagnosed as metastatic adenocarcinoma and treated with local excision and adjuvant radiotherapy in another center.
  • Diagnosis in our center was primary cutaneous eccrine mucinous adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Axilla / pathology. Eccrine Glands / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 20405690.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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32. Abhishek A, Ouseph MM, Sharma P, Kamal V, Sharma M: Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case. J Med Imaging Radiat Oncol; 2008 Feb;52(1):91-4
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  • [Title] Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case.
  • We present the case of a 53-year-old postmenopausal lady with adenocarcinoma of the uterine cervix that metastasized to the scalp with superior sagittal sinus thrombosis 8 months after diagnosis.
  • In contrast to the seven prior cases of scalp metastases of cervical squamous cell carcinoma reported in published reports, ours is the first documentation of such an occurrence in cervical adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Head and Neck Neoplasms / secondary. Scalp / pathology. Sinus Thrombosis, Intracranial / etiology. Skin Neoplasms / secondary. Uterine Cervical Neoplasms / pathology


33. Kim HJ, Kim YB, Park JW, Oh WS, Kim EO, Lim BY, Kim DY: Recurrent sebaceous carcinoma in an African hedgehog (Atelerix albiventris). J Vet Med Sci; 2010 Jul;72(7):947-9
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  • Based on these findings, a diagnosis of sebaceous carcinoma was made.

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  • (PMID = 20215722.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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34. Hamada M, Ozaki K, Iwata J, Nishioka Y, Horimi T: A case of rectosigmoid cancer metastasizing to a fistula in ano. Jpn J Clin Oncol; 2005 Nov;35(11):676-9
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  • On the left upper side of the skin surface around the anus a fistula end was seen as a hole that tunneled down into the back passage, although no hard tumor was palpable on the hole.
  • The post-operative pathological diagnosis was rectosigmoid cancer, Type 2, T2, N0, M0, stage II.
  • Pathological diagnosis of the excised fistula revealed well-differentiated adenocarcinoma; identical to the colon tumor.
  • We diagnosed this tumor as metastatic adenocarcinoma from a rectosigmoid cancer.
  • [MeSH-major] Adenocarcinoma / secondary. Anus Neoplasms / secondary. Rectal Fistula / pathology. Rectal Neoplasms / pathology. Sigmoid Neoplasms / pathology

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  • (PMID = 16275674.001).
  • [ISSN] 0368-2811
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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35. Karasavvidou F, Potamianos SP, Barbanis S, Stathakis E, Psychos A, Kapsoritakis AN, Koukoulis G: Malakoplakia of the colon associated with colonic adenocarcinoma diagnosed in colonic biopsies. World J Gastroenterol; 2007 Dec 7;13(45):6109-11
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  • [Title] Malakoplakia of the colon associated with colonic adenocarcinoma diagnosed in colonic biopsies.
  • It has also been found in many other sites such as the gastrointestinal tract, pancreas, liver, lymph nodes, skin, respiratory tract, adrenal gland, vagina and brain.
  • Biopsies of the ascending colon mass confirmed the diagnosis of adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / complications. Colonic Neoplasms / complications. Malacoplakia / complications

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  • (PMID = 18023111.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4250902
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36. Díaz R, Moral P, Fonfría M, de Juan M, Mancheño N, Tormo A: Multimodality management of a locally advanced primary oesophageal melanoma with radical surgery and adjuvant chemoimmunoradiotherapy. Clin Transl Oncol; 2010 Apr;12(4):306-9
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  • The main differential diagnosis is with metastases of skin or ocular malignant melanomas.
  • [MeSH-minor] Adenocarcinoma, Follicular / pathology. Adenocarcinoma, Follicular / surgery. Carboplatin / administration & dosage. Chemotherapy, Adjuvant. Combined Modality Therapy. Dacarbazine / administration & dosage. Esophagectomy. Female. Humans. Hypertension / complications. Immunotherapy / methods. Interferons / administration & dosage. Middle Aged. Neoplasms, Second Primary / pathology. Neoplasms, Second Primary / therapy. Radiotherapy, Adjuvant. Thyroid Neoplasms / pathology. Thyroid Neoplasms / surgery

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  • (PMID = 20462842.001).
  • [ISSN] 1699-3055
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 7GR28W0FJI / Dacarbazine; 9008-11-1 / Interferons; BG3F62OND5 / Carboplatin
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37. Añibarro Laca E, Pérez-Irezabal Pindado JC, Ibáñez Calle T, Llarena Ibarguren R: [Metastases from a rectal adenocarcinoma to the prepuce]. Arch Esp Urol; 2006 Sep;59(7):737-9
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  • [Title] [Metastases from a rectal adenocarcinoma to the prepuce].
  • [Transliterated title] Metastasis subcutáneas en prepucio secundarias a adenocarcinoma de recto.
  • OBJECTIVE: We report one case of metastatic dissemination of a rectal adenocarcinoma to the prepuce.
  • METHODS: 61-year-old patient with the diagnosis of rectal adenocarcinoma treated 18 months before by surgery and chemotherapy.
  • He presents with a painful enlargement of the penis associated with outgrowing erythematous lesions in the skin of the prepuce that bled on touch and did not allow the vision of the meatus and the glans penis.
  • RESULTS: The pathologic study reported a moderately differentiated intestinal type adenocarcinoma with high mitotic index infiltrating the squamous cell flat epithelium of the prepuce.
  • [MeSH-major] Adenocarcinoma / secondary. Penile Neoplasms / secondary. Rectal Neoplasms / pathology

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  • [CommentIn] Arch Esp Urol. 2006 Nov;59(9):926; author reply 927 [17190224.001]
  • (PMID = 17078400.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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38. Chi CC, Kuo TT, Wang SH: Aggressive digital papillary adenocarcinoma: a silent malignancy masquerading as acquired digital fibrokeratoma. Am J Clin Dermatol; 2007;8(4):243-5
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  • [Title] Aggressive digital papillary adenocarcinoma: a silent malignancy masquerading as acquired digital fibrokeratoma.
  • Aggressive digital papillary adenocarcinoma (ADPAC) is a rare cutaneous malignant tumor.
  • Consequently, re-excision with a full-thickness skin graft was performed.
  • An excisional biopsy is warranted for correct diagnosis.
  • [MeSH-major] Adenocarcinoma, Papillary / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Immunohistochemistry. Keratosis / diagnosis. Male. Thumb / pathology

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  • (PMID = 17645380.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
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39. Chang IH, Ha MS, Chi BH, Kown YW, Lee SJ: Warfarin-induced penile necrosis in a patient with heparin-induced thrombocytopenia. J Korean Med Sci; 2010 Sep;25(9):1390-3
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  • A 56-yr-old man with lung adenocarcinoma presented with subsegmental pulmonary thrombosis.
  • This case illustrates that processes underlying heparin-induced thrombocytopenia (HIT) may also underlie warfarin-induced skin necrosis.
  • [MeSH-minor] Adenocarcinoma / complications. Adenocarcinoma / diagnosis. Humans. Lung Neoplasms / complications. Lung Neoplasms / diagnosis. Male. Middle Aged. Necrosis. Penile Erection / drug effects. Platelet Count. Protein C / analysis. Protein S / analysis. Pulmonary Artery. Thrombosis / complications. Thrombosis / diagnosis. Thrombosis / drug therapy

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  • (PMID = 20808689.001).
  • [ISSN] 1598-6357
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Anticoagulants; 0 / Protein C; 0 / Protein S; 5Q7ZVV76EI / Warfarin; 9005-49-6 / Heparin
  • [Other-IDs] NLM/ PMC2923782
  • [Keywords] NOTNLM ; Heparin / Necrosis / Penis / Warfarin
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40. Greenberg HL, Lopez L, Butler DF: Peristomal metastatic adenocarcinoma of the rectum. Arch Dermatol; 2006 Oct;142(10):1372-3
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  • [Title] Peristomal metastatic adenocarcinoma of the rectum.
  • [MeSH-major] Adenocarcinoma / diagnosis. Rectal Neoplasms / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Colostomy. Diagnosis, Differential. Female. Humans. Neoplasm Metastasis

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  • (PMID = 17043208.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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41. Colla TG, Lovatto L, Duquia RP: Case for diagnosis: umbilical metastasis of pancreatic carcinoma (Sister Mary Joseph's Nodule). An Bras Dermatol; 2009 Jul;84(3):297-8
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  • [Title] Case for diagnosis: umbilical metastasis of pancreatic carcinoma (Sister Mary Joseph's Nodule).
  • Histologic examination demonstrated poorly differentiated adenocarcinoma.
  • Abdominal tomography showed advanced pancreatic cancer with metastatic involvement of the liver and the diagnosis of pancreatic adenocarcinoma with umbilical metastasis -- Sister Mary Joseph's nodule.
  • [MeSH-major] Adenocarcinoma / secondary. Pancreatic Neoplasms / pathology. Skin Neoplasms / secondary. Umbilicus / pathology

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  • (PMID = 19668947.001).
  • [ISSN] 1806-4841
  • [Journal-full-title] Anais brasileiros de dermatologia
  • [ISO-abbreviation] An Bras Dermatol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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42. Grande M, Facchini F, La Rosa M, Pozzoli GL, Leone M, Piana S, Monica B: [Carcinoma of the collecting ducts of Bellini: a case report with cutaneous metastasis as the initial clinical manifestation]. Urologia; 2010 Jan-Mar;77 Suppl 16:51-4
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  • INTRODUCTION: Bellini's collecting ducts carcinoma represents a rare tumor with an aggressive behaviour with a poor prognosis and often metastatic at diagnosis.
  • RESULTS: After reporting an histopathologic finding of cutaneous metastasis of unknown origin adenocarcinoma with poorly differentiation, a voluminous 6 cm left mesorenal mass is diagnosed through uro-CT.
  • The histopathologic diagnosis reported was Bellini tumor at stage pT3a-N2-M1.
  • It has not reported significative responsiveness to adjuvant chemotherapy and the patient was died seven months after diagnosis of cutaneous metastasis.
  • [MeSH-major] Carcinoma, Renal Cell / secondary. Kidney Neoplasms / diagnosis. Skin Neoplasms / secondary

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  • (PMID = 21104663.001).
  • [ISSN] 1724-6075
  • [Journal-full-title] Urologia
  • [ISO-abbreviation] Urologia
  • [Language] ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Levy G, Finkelstein A, McNiff JM: Immunohistochemical techniques to compare primary vs. metastatic mucinous carcinoma of the skin. J Cutan Pathol; 2010 Apr;37(4):411-5
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  • [Title] Immunohistochemical techniques to compare primary vs. metastatic mucinous carcinoma of the skin.
  • BACKGROUND: Primary and metastatic mucinous carcinomas in skin are histologically indistinguishable.
  • Immunohistochemical panels help differentiate primary and metastatic adenocarcinoma of skin, but data regarding mucinous carcinoma is scant.
  • METHODS: We stained five primary mucinous carcinomas, two mucinous carcinomas metastatic to skin and five primary breast and colon mucinous carcinomas with p63, CD15, CK5/6, CK7, CK20, calponin and D2-40 to identify patterns that might differentiate primary from metastatic disease.
  • RESULTS: All cases of primary mucinous carcinoma of the skin were positive for CK7, 40% showed rare cells labeled for p63 and 20% of cases labeled focally for CK5/6.
  • The breast mucinous carcinomas metastatic to the skin were negative for all markers except CK7, although 60% of primary breast carcinomas labeled for p63.
  • [MeSH-major] Adenocarcinoma, Mucinous / metabolism. Biomarkers, Tumor / metabolism. Immunohistochemistry / methods. Skin Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Breast Neoplasms / pathology. Diagnosis, Differential. Female. Head and Neck Neoplasms / pathology. Humans. Male. Middle Aged. Scalp

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  • (PMID = 19788442.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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44. Fernández Arjona M, Santos Arrontes D, De Castro Barbosa F, Begara Morillas F, Cortes Aranguez I, González L: [Synchronous renal clear-cell carcinoma and ipsilateral transitional-cell carcinoma: case report and bibliographic review]. Arch Esp Urol; 2005 Jun;58(5):460-3
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  • OBJECTIVES: We report a new case of simultaneous renal cell adenocarcinoma and ipsilateral multifocal transitional cell carcinoma.
  • METHODS: 73-year-old man with initial diagnosis of transitional cell carcinoma of the urinary tract whose pathological report showed a asynchronous renal cell carcinoma.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Carcinoma, Renal Cell / pathology. Carcinoma, Transitional Cell / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Ureteral Neoplasms / pathology
  • [MeSH-minor] Aged. Brain Neoplasms / secondary. Carcinoma, Squamous Cell / pathology. Facial Neoplasms / pathology. Fatal Outcome. Humans. Hydronephrosis / etiology. Male. Neoplasms, Second Primary / pathology. Nephrectomy. Nephrostomy, Percutaneous. Skin Neoplasms / pathology. Ureter / surgery


45. Dasanu CA, Alexandrescu DT: Bilateral Leser-Trélat sign mirroring lung adenocarcinoma with early metastases to the contralateral lung. South Med J; 2009 Feb;102(2):216-8
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  • [Title] Bilateral Leser-Trélat sign mirroring lung adenocarcinoma with early metastases to the contralateral lung.
  • We present a case featuring a unique overlap between the body areas involved by lung adenocarcinoma and the cutaneous paraneoplastic sign of Leser-Trélat.
  • In our patient, the Leser-Trélat sign consisted of explosive multiple seborrheic keratoses in combination with acanthosis nigricans, representing a remarkable geometric skin projection of lung cancer which involved both the upper lobes.
  • The recognition of this phenomenon may contribute to an early diagnosis and prompt surgical treatment of occult cancers.
  • [MeSH-major] Acanthosis Nigricans / pathology. Adenocarcinoma / pathology. Lung Neoplasms / pathology. Paraneoplastic Syndromes / pathology

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  • (PMID = 19209445.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Pradhan S, Asthana AK, Sharan GK, Kumar M, Sharma OP: Recurrence of carcinoma cervix in the scar of previous cesarean section: a case report. Int J Gynecol Cancer; 2006 Mar-Apr;16(2):900-4
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  • A 49-year-old female with a diagnosis of keratinizing squamous cell carcinoma (SCC) of cervix, stage IIB, was treated by radical radiotherapy.
  • Infiltration of the skin and extension into the deeper structures of the abdominal wall was present in an area of 5 x 4 cm(2).
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Squamous Cell / pathology. Cesarean Section. Cicatrix. Neoplasm Recurrence, Local. Uterine Cervical Neoplasms / pathology


47. Fornaciari G: [The Aragonese mummies of the Basilica of Saint Domenico Maggiore in Naples]. Med Secoli; 2006;18(3):843-64
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  • Domenico Maggiore in Naples has allowed us to perform about 20 diagnoses, of which 5 concern infectious (smallpox, hepatitis, condyloma, syphilis and pneumonia), 3 metabolic (obesity, atherosclerosis, gallstones), I articular (DISH) and 2 neoplastic (colon adenocarcinoma and skin carcinoma) diseases.
  • Light microscopy evidenced an exophytic, papillary skin lesion, with typical connective axis and pronounced parakeratosis.
  • This study represents the first molecular diagnosis of HPV in mummies and could pave the way for further research about the secular evolution of these viruses, very important in human oncology.
  • The mummy of Ferrante I d'Aragona, King of Naples (1431-1494), revealed an adenocarcinoma extensively infiltrating the muscles of the small pelvis.

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  • (PMID = 18175625.001).
  • [ISSN] 0394-9001
  • [Journal-full-title] Medicina nei secoli
  • [ISO-abbreviation] Med Secoli
  • [Language] ita
  • [Publication-type] English Abstract; Historical Article; Journal Article
  • [Publication-country] Italy
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48. Kazakov DV, Kutzner H, Rütten A, Mukensnabl P, Michal M: Carcinoid-like pattern in sebaceous neoplasms: another distinctive, previously unrecognized pattern in extraocular sebaceous carcinoma and sebaceoma. Am J Dermatopathol; 2005 Jun;27(3):195-203
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  • The cases included 6 men and 1 woman, with their ages at the diagnosis ranging from 43 to 87 years (median age, 59).
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Biomarkers, Tumor / analysis. Carcinoid Tumor / pathology. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / pathology. Diagnosis, Differential. Female. History, 16th Century. Humans. Immunohistochemistry. Inclusion Bodies / pathology. Male. Microscopy, Electron, Transmission. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / ultrastructure. Neoplasms, Adnexal and Skin Appendage / pathology

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  • (PMID = 15900121.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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49. Oudidi A, El-Alami MN, Boulaich M, Jazouli N, Kzadri M: [Primary sub-mandibular gland tumours: experience based on 68 cases]. Rev Laryngol Otol Rhinol (Bord); 2006;127(3):187-90
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  • Clinical suspicion of malignancy was associated with symptom of pain, cervical adenopathy, nerve palsy, skin and/or bone invasion.
  • Definitive diagnosis was by complete excision and pathological examination.
  • For malignant lesions (n= 31) the most frequent were: Adenoid cystic carcinoma (n= 10), epidermoid carcinoma (n= 5), adenocarcinoma (n= 5), mucoepidermoid carcinoma (n= 3), malignant non Hodgkinien lymphoma (n= 5).
  • Any delay in diagnosis or inappropriate management may result in a poor prognosis for the patient.
  • [MeSH-major] Submandibular Gland Neoplasms / classification. Submandibular Gland Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Early Diagnosis. Female. Humans. Male. Middle Aged. Prognosis

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  • (PMID = 17007195.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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50. Lou SX, Wang LX, Shi HQ: [Extramammary Paget's disease due to underlying anal canal adenocarcinoma]. Zhonghua Bing Li Xue Za Zhi; 2006 Nov;35(11):701
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  • [Title] [Extramammary Paget's disease due to underlying anal canal adenocarcinoma].
  • [MeSH-major] Anus Neoplasms / pathology. Paget Disease, Extramammary / secretion. Skin Neoplasms / secretion
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / secondary. Adenocarcinoma / surgery. Anal Canal / chemistry. Anal Canal / pathology. Anal Canal / surgery. Carcinoembryonic Antigen / analysis. Diagnosis, Differential. Humans. Immunohistochemistry. Keratin-20 / analysis. Male. Middle Aged. Mucin-1 / analysis

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  • (PMID = 17374224.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Keratin-20; 0 / Mucin-1
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51. Huang YJ, Liu SF, Wang CJ, Huang MY: Exacerbated radiodermatitis and bilateral subdural hemorrhage after whole brain irradiation combined with epidermal growth factor receptor tyrosine kinase inhibitors for brain metastases in lung cancer. Lung Cancer; 2008 Mar;59(3):407-10
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  • A 57-year-old male developed an adenocarcinoma lung cancer in November 2003.
  • The targeted therapy gefitinib was prescribed 2 years after diagnosis, producing a very good partial response.
  • Unexpectedly, the patient developed a severe skin reaction in the region exposed to the radiation field, and a bilateral subdural hemorrhage, following radiation therapy.


52. Lukáts O: [Oncological principles of surgery in the periorbital region]. Magy Onkol; 2005;49(1):47-52
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  • Diagnosis in some of the cases is difficult, since the first signs of the tumours are small changes on the eyelid margin or eyelid skin.
  • Therefore, early diagnosis and total tumour removal--regardless of the anatomical borders--as well as immediate reconstruction are important in the treatment of eyelid tumours.
  • [MeSH-major] Eyelid Neoplasms / surgery. Orbital Neoplasms / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma, Sebaceous / surgery. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Humans. Melanoma / surgery. Ophthalmologic Surgical Procedures / methods. Sebaceous Gland Neoplasms / surgery. Surgical Procedures, Operative / methods

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  • (PMID = 15902334.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Hungary
  • [Number-of-references] 23
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53. Marazza G, Masouyé I, Taylor S, Prins C, Gaudin T, Saurat JH, French LE: An illustrative case of Muir-Torre syndrome: contribution of immunohistochemical analysis in identifying indicator sebaceous lesions. Arch Dermatol; 2006 Aug;142(8):1039-42
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  • OBSERVATIONS: We report the case of a 54-year-old man with a 2-year history of skin-colored papules clinically reminiscent of large sebaceous hyperplasias on the nose and back, but histologically diagnosed as sebaceous adenomas and epitheliomas.
  • CONCLUSION: The immunohistochemical testing for MSH-2, MSH-6, and MLH-1 is useful for rapid identification of an underlying mismatch repair defect and early diagnosis of MTS.
  • [MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Colorectal Neoplasms, Hereditary Nonpolyposis. Sebaceous Gland Neoplasms / diagnosis
  • [MeSH-minor] Back / pathology. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged. MutS Homolog 2 Protein / metabolism. Nose / pathology

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  • (PMID = 16924054.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.6.1.3 / MSH2 protein, human; EC 3.6.1.3 / MutS Homolog 2 Protein
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54. Dragovich T, McCoy S, Fenoglio-Preiser CM, Wang J, Benedetti JK, Baker AF, Hackett CB, Urba SG, Zaner KS, Blanke CD, Abbruzzese JL: Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127. J Clin Oncol; 2006 Oct 20;24(30):4922-7
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  • PATIENTS AND METHODS: Patients with a histologically proven diagnosis of adenocarcinoma of the GEJ or stomach (ST) that was unresectable or metastatic; presence of measurable disease; no prior chemotherapy for advanced or metastatic cancer; Zubrod performance status (PS) of 0 to 1; and adequate renal, hepatic, and hematologic function were treated with erlotinib 150 mg/d orally.
  • RESULTS: Percentage of common toxicities were skin rash, 86% and 72%; fatigue, 51% and 44%; and AST/ALT elevation, 28% and 28%, respectively for GEJ and ST.

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  • [CommentIn] J Clin Oncol. 2007 Mar 1;25(7):910; author reply 911 [17327617.001]
  • [ErratumIn] J Clin Oncol. 2007 Jun 1;25(16):2334
  • (PMID = 17050876.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA04919; United States / NCI NIH HHS / CA / CA11083; United States / NCI NIH HHS / CA / CA12644; United States / NCI NIH HHS / CA / CA13612; United States / NCI NIH HHS / CA / CA14028; United States / NCI NIH HHS / CA / CA16385; United States / NCI NIH HHS / CA / CA22433; United States / NCI NIH HHS / CA / CA27057; United States / NCI NIH HHS / CA / CA32102; United States / NCI NIH HHS / CA / CA35090; United States / NCI NIH HHS / CA / CA35128; United States / NCI NIH HHS / CA / CA35176; United States / NCI NIH HHS / CA / CA35178; United States / NCI NIH HHS / CA / CA35192; United States / NCI NIH HHS / CA / CA35431; United States / NCI NIH HHS / CA / CA38926; United States / NCI NIH HHS / CA / CA42777; United States / NCI NIH HHS / CA / CA45450; United States / NCI NIH HHS / CA / CA45560; United States / NCI NIH HHS / CA / CA45807; United States / NCI NIH HHS / CA / CA45808; United States / NCI NIH HHS / CA / CA46441; United States / NCI NIH HHS / CA / CA58658; United States / NCI NIH HHS / CA / CA58686; United States / NCI NIH HHS / CA / CA58723; United States / NCI NIH HHS / CA / CA58882; United States / NCI NIH HHS / CA / CA63848; United States / NCI NIH HHS / CA / CA63850; United States / NCI NIH HHS / CA / CA67575; United States / NCI NIH HHS / CA / CA67663; United States / NCI NIH HHS / CA / CA76447; United States / NCI NIH HHS / CA / CA76448; United States / NCI NIH HHS / CA / CA86780
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Protein Kinase Inhibitors; 0 / Quinazolines; DA87705X9K / Erlotinib Hydrochloride
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55. Zhao YY, Zhang Y, Zhao HY, Wu JX, Jiang W, Xue C, Zhang L: [Predictive factors for response and survival of gefitinib-treated locally advanced or metastatic non-small cell lung cancer patients: a retrospective analysis of two phase II clinical trials]. Ai Zheng; 2009 Jun;28(6):626-31
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  • Adenocarcinoma and skin rash were associated with better response.
  • CONCLUSIONS: Adenocarcinoma and skin rash are predictors of better response to gefitinib.
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / pathology. Adult. Aged. Aged, 80 and over. Clinical Trials, Phase II as Topic. Disease Progression. Exanthema / chemically induced. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Staging. Remission Induction. Retrospective Studies. Survival Rate. Young Adult


56. Miyamoto T, Adachi K, Fujishima M: Axillary apocrine carcinoma with Paget's disease and apocrine naevus. Clin Exp Dermatol; 2009 Jul;34(5):e110-3
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  • The resected specimen showed apocrine adenocarcinoma with extramammary Paget's disease and apocrine naevus.
  • [MeSH-major] Adenocarcinoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Nevus / diagnosis. Paget Disease, Extramammary / diagnosis. Skin Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Aged. Apocrine Glands. Axilla. Humans. Male. Positron-Emission Tomography. Precancerous Conditions / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 19438526.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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57. Yang HM, Cabral E, Dadras SS, Cassarino DS: Immunohistochemical expression of D2-40 in benign and malignant sebaceous tumors and comparison to basal and squamous cell carcinomas. Am J Dermatopathol; 2008 Dec;30(6):549-54
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  • The diagnosis of sebaceous carcinoma presents an important challenge to both clinicians and pathologists, as many cases are initially misdiagnosed both clinically and histopathologically, potentially leading to adverse medical and legal outcomes.
  • We studied the expression of D2-40 (podoplanin) by immunohistochemistry to determine if it can aid in this differential diagnosis and to evaluate the possibility of lymphangiogenesis in sebaceous carcinoma.
  • [MeSH-major] Adenocarcinoma, Sebaceous / metabolism. Antibodies, Monoclonal / metabolism. Carcinoma, Basal Cell / metabolism. Carcinoma, Squamous Cell / metabolism. Sebaceous Gland Neoplasms / metabolism. Sebaceous Glands / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Adenoma / diagnosis. Adenoma / metabolism. Adenoma / pathology. Antibodies, Monoclonal, Murine-Derived. Biomarkers, Tumor / metabolism. Case-Control Studies. Cell Proliferation. Diagnosis, Differential. Humans. Hyperplasia / diagnosis. Hyperplasia / metabolism. Hyperplasia / pathology

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  • (PMID = 19033927.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Biomarkers, Tumor; 0 / monoclonal antibody D2-40
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58. Yendluri V, Centeno B, Springett GM: Pancreatic cancer presenting as a Sister Mary Joseph's nodule: case report and update of the literature. Pancreas; 2007 Jan;34(1):161-4
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  • We report a case of pancreatic adenocarcinoma in which the initial presenting sign was a SMJN.
  • This case emphasizes that pancreatic cancer should be considered in the differential diagnosis of umbilical metastasis.
  • [MeSH-major] Adenocarcinoma / secondary. Pancreatic Neoplasms / pathology. Skin Neoplasms / secondary. Umbilicus
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Humans. Laparoscopy. Tomography, X-Ray Computed

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  • (PMID = 17198200.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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59. Policarpio-Nicolas ML, Nicolas MM, Keh P, Laskin WB: Postradiation angiosarcoma of the small intestine: a case report and review of literature. Ann Diagn Pathol; 2006 Oct;10(5):301-5
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  • Postradiation angiosarcoma is typically a high-grade sarcoma that presents mainly in the skin and superficial tissues.
  • Herein, we report a postradiation angiosarcoma of the small intestine 9 years after radiotherapy for uterine cervical adenocarcinoma.
  • The diagnosis of angiosarcoma was confirmed immunohistochemically by tumor cell expression of CD31, CD34, and factor VIII-related antigen.
  • The diagnosis of PRA should be entertained for any poorly differentiated neoplasm arising in a previously irradiated site.
  • The correct diagnosis of PRA depends upon histomorphologic identification of vascular differentiation, coupled with immunohistochemical expression of endothelial-related markers.
  • [MeSH-major] Hemangiosarcoma / etiology. Intestinal Neoplasms / etiology. Intestine, Small. Neoplasms, Radiation-Induced / diagnosis
  • [MeSH-minor] Adenocarcinoma / radiotherapy. Antigens, CD31 / metabolism. Antigens, CD34 / metabolism. Cell Transformation, Neoplastic / pathology. Factor VIII / metabolism. Fatal Outcome. Female. Gene Expression Regulation, Neoplastic. Humans. Intestinal Obstruction / etiology. Middle Aged. Prognosis. Uterine Cervical Neoplasms / radiotherapy

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  • (PMID = 16979525.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Antigens, CD34; 9001-27-8 / Factor VIII
  • [Number-of-references] 17
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60. Bindra M, Keegan DJ, Guenther T, Lee V: Primary cutaneous mucinous carcinoma of the eyelid in a young male. Orbit; 2005 Sep;24(3):211-4
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  • Primary cutaneous mucinous carcinoma of the eyelid is an adenocarcinoma of the eccrine glands.
  • The defect was repaired with an upper eyelid skin graft.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / surgery. Eyelid Neoplasms / pathology. Eyelid Neoplasms / surgery
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Mohs Surgery

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  • (PMID = 16169809.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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61. Segawa M, Kusajima Y, Saito K: [Pleomorphic carcinoma of the lung rapidly developed multiple metastases after surgery]. Kyobu Geka; 2006 May;59(5):387-91
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  • Pleomorphic carcinoma of the lung is a type of carcinoma with spindle and/or giant cells with a poor diagnosis.
  • Lung biopsy revealed that the tumor was poorly differentiated adenocarcinoma.
  • Histological findings showed adenocarcinoma comprised of spindle cell components that reacted positively to epithelial membrane antigen (EMA) and no lymph node metastasis.
  • But metastatic lesions newly appeared in the thoracic skin, the liver, the diaphragm, the bilateral adrenal glands, and the retroperitoneal space on the 30th postoperative day.
  • [MeSH-major] Adenocarcinoma / secondary. Carcinoma / secondary. Lung Neoplasms / pathology. Pneumonectomy
  • [MeSH-minor] Adrenal Cortex Neoplasms / secondary. Aged. Humans. Liver Neoplasms / secondary. Lymph Node Excision. Male. Neoplasms, Multiple Primary. Postoperative Period. Retroperitoneal Neoplasms / secondary. Skin Neoplasms / secondary

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  • (PMID = 16715890.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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62. Sramek B, Lisle A, Loy T: Immunohistochemistry in ocular carcinomas. J Cutan Pathol; 2008 Jul;35(7):641-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Biomarkers, Tumor / metabolism. Carcinoma, Basal Cell / pathology. Carcinoma, Squamous Cell / pathology. Eye Neoplasms / pathology. Sebaceous Gland Neoplasms / pathology. Skin / pathology
  • [MeSH-minor] Biomarkers / metabolism. Diagnosis, Differential. Humans. Immunohistochemistry. Keratin-7 / metabolism. Keratins / metabolism. Mucin-1 / metabolism. Receptors, Androgen / metabolism

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  • (PMID = 18201230.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Biomarkers, Tumor; 0 / CAM 5.2 antigen; 0 / Keratin-7; 0 / Mucin-1; 0 / Receptors, Androgen; 0 / human epithelial antigen-125; 68238-35-7 / Keratins
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63. Torné J, Bonaut B, Sanz C, Martínez C, Torrero MV, Miranda-Romero A: [Cutaneous metastases of rectal adenocarcinoma in a herpetiform distribution]. Actas Dermosifiliogr; 2006 Apr;97(3):206-7
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  • [Title] [Cutaneous metastases of rectal adenocarcinoma in a herpetiform distribution].
  • [Transliterated title] Metástasis cutáneas de adenocarcinoma de recto con distribución herpetiforme.
  • We present the case of a 62-year-old male with cutaneous metastases of a rectal adenocarcinoma located on the groin and left thigh.
  • They may mimic benign skin lesions like epidermoid cysts, lipomas, erysipelas or, as in our case, herpes zoster.
  • [MeSH-major] Carcinoma, Signet Ring Cell / secondary. Diagnostic Errors. Rectal Neoplasms / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Anemia / etiology. Diarrhea / etiology. Groin. Herpes Zoster / diagnosis. Humans. Male. Middle Aged. Thigh

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  • (PMID = 16796970.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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64. Plaza JA, Ortega PF, Stockman DL, Suster S: Value of p63 and podoplanin (D2-40) immunoreactivity in the distinction between primary cutaneous tumors and adenocarcinomas metastatic to the skin: a clinicopathologic and immunohistochemical study of 79 cases. J Cutan Pathol; 2010 Apr;37(4):403-10
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  • [Title] Value of p63 and podoplanin (D2-40) immunoreactivity in the distinction between primary cutaneous tumors and adenocarcinomas metastatic to the skin: a clinicopathologic and immunohistochemical study of 79 cases.
  • The distinction of metastatic carcinomas to the skin from poorly differentiated primary cutaneous carcinomas and sometimes primary benign adnexal tumors can pose a significant diagnostic challenge.
  • The purpose of this study was to evaluate the role of p63 and podoplanin (D2-40) immunoreactivity for separating primary skin tumors vs. cutaneous metastases of carcinomas from internal organs.
  • The 37 primary cutaneous tumors included 14 cases of benign adnexal tumors, 9 malignant skin adnexal neoplasms, and 14 primary squamous and basal cell carcinomas.
  • Sensitivity, specificity, and positive and negative predictive values of podoplanin and p63 immunoreactivity to separate primary skin neoplasms from metastatic carcinomas were 78.4, 100.0, 100.0 and 84.0% for podoplanin, respectively, and 100.0, 100.0, 100.0 and 100.0% for p63, respectively.
  • The differences in p63 and podoplanin immunohistochemical expression between primary skin tumors and metastatic carcinomas to the skin were statistically significant (p < 0, 0001).
  • The results of our study suggest that the combined expression of p63 and podoplanin are a useful adjunct for the diagnosis of skin tumors in the clinical setting of a questionable metastasis and may be relatively specific for distinguishing primary skin tumors from metastatic carcinomas to the skin.
  • [MeSH-major] Adenocarcinoma / metabolism. Membrane Glycoproteins / metabolism. Membrane Proteins / metabolism. Skin / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry

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  • (PMID = 20377670.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CKAP4 protein, human; 0 / Membrane Glycoproteins; 0 / Membrane Proteins; 0 / PDPN protein, human
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66. Ivan D, Diwan AH, Lazar AJ, Prieto VG: The usefulness of p63 detection for differentiating primary from metastatic skin adenocarcinomas. J Cutan Pathol; 2008 Sep;35(9):880-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The usefulness of p63 detection for differentiating primary from metastatic skin adenocarcinomas.
  • [MeSH-major] Adenocarcinoma / diagnosis. Biomarkers, Tumor / metabolism. Membrane Proteins / metabolism. Neoplasms, Adnexal and Skin Appendage / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Immunohistochemistry

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  • [CommentOn] J Cutan Pathol. 2008 Jul;35(7):692-3 [18312438.001]
  • (PMID = 18796086.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CKAP4 protein, human; 0 / Membrane Proteins
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67. Barbosa LA, Teixeira CR: Erythema multiforme associated with prophylactic use of phenytoin during cranial radiation therapy. Am J Health Syst Pharm; 2008 Jun 1;65(11):1048-50
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  • SUMMARY: A 60-year-old woman with intraductal adenocarcinoma of the breast and cerebral metastasis who had an implanted central venous catheter arrived at the hospital for the treatment of cerebral metastasis.
  • After 30 days of continuous prophylactic phenytoin and cranial radiation therapy, the patient developed an episode of coughing with yellow sputum, mucositis, and a minor skin reaction that was diagnosed in the emergency department as radiotherapy-associated lesions.
  • The condition had worsened by the next day, with erythematous eruptions on the whole body (including the extremities), skin detachment, and vesicular lesions on the eyelids.
  • CONCLUSION: A patient with intraductal adenocarcinoma of the breast and cerebral metastasis developed erythema multiforme after receiving concurrent phenytoin and radiation therapy.
  • [MeSH-minor] Breast Neoplasms / pathology. Breast Neoplasms / radiotherapy. Cranial Irradiation / adverse effects. Female. Humans. Middle Aged. Seizures / etiology. Seizures / prevention & control. Stevens-Johnson Syndrome / diagnosis. Stevens-Johnson Syndrome / etiology

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  • (PMID = 18499877.001).
  • [ISSN] 1535-2900
  • [Journal-full-title] American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
  • [ISO-abbreviation] Am J Health Syst Pharm
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants; 6158TKW0C5 / Phenytoin
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68. Liam CK, Pang YK, Leow CH: Epidermal growth factor receptor targeted therapy with gefitinib in locally advanced and metastatic primary lung adenocarcinoma. Respirology; 2006 May;11(3):287-91
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  • [Title] Epidermal growth factor receptor targeted therapy with gefitinib in locally advanced and metastatic primary lung adenocarcinoma.
  • OBJECTIVE: To describe the efficacy of monotherapy with the epidermal growth factor receptor-tyrosine kinase inhibitor, gefitinib in patients with locally advanced and metastatic primary lung adenocarcinoma.
  • METHODS: A retrospective analysis was undertaken of patients who had locally advanced or metastatic lung adenocarcinoma treated with gefitinib 250 mg orally once daily until disease progression.
  • Response was not affected by the patient's age, gender, disease stage, prior chemotherapy treatment, interval between diagnosis and commencement of gefitinib or the development of skin toxicity.
  • CONCLUSION: When given alone, gefitinib showed significant antitumour activity in patients with locally advanced and metastatic primary lung adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Agents / therapeutic use. Lung Neoplasms / drug therapy. Quinazolines / therapeutic use. Receptor, Epidermal Growth Factor / drug effects

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  • [CommentIn] Respirology. 2006 Nov;11(6):835; author reply 836 [17052320.001]
  • (PMID = 16635086.001).
  • [ISSN] 1323-7799
  • [Journal-full-title] Respirology (Carlton, Vic.)
  • [ISO-abbreviation] Respirology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Quinazolines; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; S65743JHBS / gefitinib
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69. Njiaju UO, Truica CI: Metastatic prostatic adenocarcinoma mimicking inflammatory breast carcinoma: a case report. Clin Breast Cancer; 2010 Feb;10(1):E3-5
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  • [Title] Metastatic prostatic adenocarcinoma mimicking inflammatory breast carcinoma: a case report.
  • Prostate adenocarcinoma can manifest as a fairly indolent tumor or as a very aggressive cancer with significant invasive and metastatic potential.
  • We present a case of a man who presented with breast skin changes that mimicked inflammatory breast carcinoma with specialized testing ultimately giving a diagnosis of metastatic prostatic adenocarcinoma.
  • A skin biopsy showed metastatic carcinoma in dermal lymphatics, and the tumor was found to have no estrogen or progesterone receptors or HER2 expression.
  • The patient received a 3-month course of capecitabine and cyclophosphamide with no improvement in his skin lesions.
  • Subsequent immunohistochemical staining on the tumor specimen was positive for prostate-specific antigen (PSA) and alpha-methyl-CoA-racemase, confirming a diagnosis of metastatic prostatic adenocarcinoma.
  • He received leuprolide and bicalutamide and demonstrated significant improvement with near-complete resolution of his skin lesions and a decrease in his PSA level.
  • Prostatic adenocarcinoma presenting initially as a breast malignancy is a rarely recognizable clinical event.
  • [MeSH-major] Adenocarcinoma / secondary. Breast Neoplasms, Male / secondary. Prostatic Neoplasms / pathology


70. Hennig R, Ventura J, Segersvard R, Ward E, Ding XZ, Rao SM, Jovanovic BD, Iwamura T, Talamonti MS, Bell RH Jr, Adrian TE: LY293111 improves efficacy of gemcitabine therapy on pancreatic cancer in a fluorescent orthotopic model in athymic mice. Neoplasia; 2005 Apr;7(4):417-25
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  • Pancreatic cancer has an abysmal prognosis because of late diagnosis and lack of effective therapeutics.
  • Monitoring of the surgical procedure and follow-up examinations at 2, 3, and 4 weeks after implantation to monitor tumor growth and metastases were performed using a fluorescence microscope and the reversible skin-flap technique.
  • It is well tolerated and can be administered orally and, therefore, provides a new hope for patients suffering from pancreatic adenocarcinoma.

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  • (PMID = 15967119.001).
  • [ISSN] 1522-8002
  • [Journal-full-title] Neoplasia (New York, N.Y.)
  • [ISO-abbreviation] Neoplasia
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA072712; United States / NCI NIH HHS / CA / CA72712
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzoates; 0 / LY 293111; 0W860991D6 / Deoxycytidine; 147336-22-9 / Green Fluorescent Proteins; B76N6SBZ8R / gemcitabine
  • [Other-IDs] NLM/ PMC1501143
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71. Pozdnyakova O, Hoang MM, Dresser KA, Mahalingam M: Prognostic value of E-cadherin, beta-catenin, CD44v6, and HER2/neu in metastatic cutaneous adenocarcinoma. Arch Pathol Lab Med; 2009 Aug;133(8):1285-90
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  • [Title] Prognostic value of E-cadherin, beta-catenin, CD44v6, and HER2/neu in metastatic cutaneous adenocarcinoma.
  • CONTEXT: Our recent experience with a patient developing cutaneous metastases within 3 months of diagnosis of esophageal adenocarcinoma suggests that altered expression of the cellular adhesion molecules, E-cadherin and CD44v6, may have had a role to play in the rapid onset of metastases.
  • DESIGN: E-cadherin, beta-catenin, CD44v6, and HER2/neu immunohistochemical stains were performed on archival materials of metastatic adenocarcinoma to the skin from 27 patients and the available corresponding primary tumors in 10 patients.
  • [MeSH-major] Adenocarcinoma / metabolism. Biomarkers, Tumor / metabolism. Esophageal Neoplasms / metabolism. Neoplasm Proteins / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 19653727.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers, Tumor; 0 / CD44v6 antigen; 0 / Cadherins; 0 / Neoplasm Proteins; 0 / beta Catenin; EC 2.7.10.1 / Receptor, ErbB-2
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72. Zangrilli A, Saraceno R, Sarmati L, Orlandi A, Bianchi L, Chimenti S: Erysipeloid cutaneous metastasis from bladder carcinoma. Eur J Dermatol; 2007 Nov-Dec;17(6):534-6
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  • We describe a 56-year-old female with a history of bladder adenocarcinoma (T3N0M0) who presented erythematous plaques with an erysipelas-like appearance located on the groins and thighs.
  • Histopathology and immunohistochemistry from skin lesions were consistent with metastases from bladder carcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Skin Neoplasms / secondary. Urinary Bladder Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Erysipelas / diagnosis. Female. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 17951136.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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73. Smymiotis V, Theodosopoulos T, Marinis A, Goula K, Psychogios J, Kondi-Pafiti A: Metastatic disease in the breast from nonmammary neoplasms. Eur J Gynaecol Oncol; 2005;26(5):547-50
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  • The primary malignancies were equally distributed between non-hematological (1 renal adenocarcinoma, 1 melanoma, 1 leiomyosarcoma) and hematological (1 non-Hodgkin's, 2 Hodgkin's lymphomas and 1 leukemia).
  • [MeSH-major] Breast Neoplasms / diagnosis. Breast Neoplasms / secondary
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / secondary. Adolescent. Adult. Aged. Breast Neoplasms, Male / diagnosis. Breast Neoplasms, Male / secondary. Diagnosis, Differential. Female. Hodgkin Disease / diagnosis. Humans. Kidney Neoplasms / diagnosis. Kidney Neoplasms / secondary. Leiomyosarcoma / diagnosis. Leiomyosarcoma / secondary. Leukemia / diagnosis. Lymphoma, Non-Hodgkin / diagnosis. Male. Melanoma / diagnosis. Melanoma / secondary. Neoplasm Metastasis. Skin Neoplasms / diagnosis. Skin Neoplasms / secondary. Uterine Neoplasms / diagnosis. Uterine Neoplasms / secondary

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  • (PMID = 16285577.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 24
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74. Kang MJ, Kim MA, Park CM, Lee CH, Goo JM, Lee HJ: Ground-glass nodules found in two patients with malignant melanomas: different growth rate and different histology. Clin Imaging; 2010 Sep-Oct;34(5):396-9
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  • [MeSH-major] Adenocarcinoma, Bronchiolo-Alveolar / diagnosis. Lung Neoplasms / diagnosis. Lung Neoplasms / secondary. Melanoma / diagnosis. Skin Neoplasms / pathology. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Aged. Diagnosis, Differential. Follow-Up Studies. Humans. Lung / radiography. Lung / surgery. Male. Middle Aged


75. Martin SK, Agarwal G, Lynch GR: Subcutaneous fat necrosis as the presenting feature of a pancreatic carcinoma: the challenge of differentiating endocrine and acinar pancreatic neoplasms. Pancreas; 2009 Mar;38(2):219-22
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  • Previous pathological evaluation of the patient's liver biopsy led to an initial diagnosis of adenocarcinoma of unknown primary site.
  • Immunohistochemistry was consistent with neuroendocrine differentiation, but the patient rapidly decompensated and died before the evaluation was complete, leaving the definitive diagnosis in question.
  • Accurate diagnosis of these tumors is necessary to determine prognosis and define appropriate therapy.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Fat Necrosis / pathology. Neuroendocrine Tumors / pathology. Pancreatic Neoplasms / pathology. Panniculitis / pathology. Skin / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 19238022.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Cholongitas E, Pipili C, Ioannidou D: Malassezia folliculitis presented as acneiform eruption after cetuximab administration. J Drugs Dermatol; 2009 Mar;8(3):274-5
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  • A 85-year-old male with a diagnosis of adenocarcinoma of the right parotid gland referred to our department for persistent acneiform eruption on the face and trunk induced after cetuximab administration.
  • Despite cetuximab discontinuation and administration of antibiotics as well as topical steroids, the skin lesions were persisted for several months.
  • [MeSH-major] Acneiform Eruptions / diagnosis. Antibodies, Monoclonal / adverse effects. Antineoplastic Agents / adverse effects. Dermatomycoses / diagnosis. Drug Eruptions / diagnosis. Folliculitis / diagnosis. Malassezia. Receptor, Epidermal Growth Factor / antagonists & inhibitors
  • [MeSH-minor] Aged. Antibodies, Monoclonal, Humanized. Cetuximab. Diagnosis, Differential. Humans. Male

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  • (PMID = 19271376.001).
  • [ISSN] 1545-9616
  • [Journal-full-title] Journal of drugs in dermatology : JDD
  • [ISO-abbreviation] J Drugs Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; PQX0D8J21J / Cetuximab
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77. Kullmann F, Hollerbach S, Dollinger MM, Harder J, Fuchs M, Messmann H, Trojan J, Gäbele E, Hinke A, Hollerbach C, Endlicher E: Cetuximab plus gemcitabine/oxaliplatin (GEMOXCET) in first-line metastatic pancreatic cancer: a multicentre phase II study. Br J Cancer; 2009 Apr 7;100(7):1032-6
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  • Eligible subjects had histological or cytological diagnosis of metastatic pancreatic adenocarcinoma.
  • Cetuximab-attributable skin reactions occurred as follows: grade 0: 20%, grade 1: 41%, grade 2: 30% and grade 3: 10%.
  • The presence of a grade 2 or higher skin rash was associated with a higher likelihood of achieving objective response.

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  • (PMID = 19293797.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine; PQX0D8J21J / Cetuximab
  • [Other-IDs] NLM/ PMC2670003
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78. Matsuda K, Doi T, Kosaka H, Tasaki N, Yoshioka H, Kakibuchi M: Sebaceous carcinoma arising in nevus sebaceus. J Dermatol; 2005 Aug;32(8):641-4
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  • A wide local excision of the area including a superficial parotidectomy and submandibular lymph node dissection was performed, followed by full thickness skin grafting.
  • [MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Nevus / diagnosis. Sebaceous Gland Neoplasms / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Cheek. Diagnosis, Differential. Female. Humans. Middle Aged. Neoplasms, Multiple Primary

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  • (PMID = 16334864.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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79. Doi M, Sugiyama T, Izumiyama H, Yoshimoto T, Hirata Y: Clinical features and management of ectopic ACTH syndrome at a single institute in Japan. Endocr J; 2010;57(12):1061-9
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  • Their salient clinical manifestations included Cushingoid feature (88%), skin pigmentation (88%), profound hypokalemia (88%), hypertension (75%), diabetes/impaired glucose tolerance (75%), hyperlipidemia (69%), and severe infection (44%).
  • Six cases deceased, including small cell carcinoma (2) and adenocarcinoma (1) of lung, neuroendocrine carcinoma of pancreas (1) and stomach (1), and olfactory neuroblastoma (1), whereas 4 cases survived after removal of the tumors, including bronchial carcinoid tumor (3) and thymic hyperplasia (1).
  • [MeSH-major] ACTH Syndrome, Ectopic / diagnosis
  • [MeSH-minor] Adrenocorticotropic Hormone / blood. Adult. Aged. Corticotropin-Releasing Hormone. Dexamethasone. Diabetes Mellitus. Diagnosis, Differential. Female. Glucose Intolerance. Humans. Hydrocortisone / blood. Hyperlipidemias. Hypertension. Hypokalemia. Japan. Male. Metyrapone / therapeutic use. Middle Aged. Neoplasms / diagnosis. Neoplasms / secretion. Neoplasms / surgery. Pituitary ACTH Hypersecretion. Skin Pigmentation. Tomography, X-Ray Computed

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  • (PMID = 21076235.001).
  • [ISSN] 1348-4540
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 7S5I7G3JQL / Dexamethasone; 9002-60-2 / Adrenocorticotropic Hormone; 9015-71-8 / Corticotropin-Releasing Hormone; WI4X0X7BPJ / Hydrocortisone; ZS9KD92H6V / Metyrapone
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80. Zurac S, Micu G, Bastian A, Grămadă E, Lavric L, Andrei R, Stăniceanu F, Voiosu R, Croitoru A: Malignancy and overdiagnosis of malignancy in Peutz Jeghers polyposis. Rom J Intern Med; 2008;46(2):179-84
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  • Peutz Jeghers (PJ) polyps are rare hamartomatous tumors of the gastrointestinal tract frequently associated with skin and mucosal pigmentation.
  • Two of these cases were related (mother and daughter); both of them were operated in another hospital for small bowel tumors with a subsequent diagnosis of adenocarcinoma.
  • The daughter (28 years old) was referred to our hospital for endoscopic follow-up; a small polyp of the transverse large bowel was excised by colonoscopy with a histopathologic diagnosis of PJ polyp; a careful histopathologic reevaluation of both specimens of enterectomy (slides and paraffin blocks) revealed an overdiagnosis of cancer due to the epithelial cystic dilatation and pseudoinvasion in both patients.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Intestinal Neoplasms / pathology. Intestinal Polyps / pathology. Peutz-Jeghers Syndrome / diagnosis. Stomach Neoplasms / pathology

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  • (PMID = 19284092.001).
  • [ISSN] 1220-4749
  • [Journal-full-title] Romanian journal of internal medicine = Revue roumaine de médecine interne
  • [ISO-abbreviation] Rom J Intern Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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81. Kalialis LV, Breiting LB, Klausen S, Dahlstrøm K: [Primary mucinous carcinoma of the skin]. Ugeskr Laeger; 2008 Oct 20;170(43):3403-4
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  • [Title] [Primary mucinous carcinoma of the skin].
  • Primary mucinous carcinoma of the skin is a rare malignant tumour originating from the sweat glands.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Head and Neck Neoplasms / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Lymphatic Metastasis. Middle Aged. Sweat Gland Neoplasms / pathology. Sweat Gland Neoplasms / secondary. Sweat Gland Neoplasms / surgery

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  • (PMID = 18976594.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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82. França AE, Salvino LK, Leite SH, Ferraz JG, Rocha TD, Cintra ML, Velho PE, Souza EM: Pyoderma gangrenosum as first clinical manifestation of gastric adenocarcinoma. J Eur Acad Dermatol Venereol; 2006 Apr;20(4):440-1
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  • [Title] Pyoderma gangrenosum as first clinical manifestation of gastric adenocarcinoma.
  • Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown etiology characterized by typical skin ulcers.
  • In this setting, we describe a patient in whom PG was the first and isolated manifestation of advanced gastric adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / complications. Adenocarcinoma / diagnosis. Pyoderma Gangrenosum / complications. Pyoderma Gangrenosum / diagnosis. Stomach Neoplasms / complications. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Fatal Outcome. Gastroscopy. Humans. Male

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  • (PMID = 16643144.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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83. Morelli U, Cirocchi R, Mecarelli V, Farinella E, La Mura F, Ronca P, Giustozzi G, Sciannameo F: Gastric adenocarcinoma cutaneous metastasis arising at a previous surgical drain site: a case report. J Med Case Rep; 2009;3:65
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  • [Title] Gastric adenocarcinoma cutaneous metastasis arising at a previous surgical drain site: a case report.
  • INTRODUCTION: Skin metastasis from internal carcinoma rarely occurs.
  • CASE PRESENTATION: A 90-year-old female patient was admitted to our surgical division with a diagnosis of anemia from a bleeding gastric adenocarcinoma.
  • Biopsies characterized it as a cutaneous metastasis from the gastric adenocarcinoma.
  • CONCLUSION: Skin metastasis from carcinomas of the upper gastrointestinal tract is very rare.

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  • [Cites] Eur J Surg Oncol. 1999 Oct;25(5):546-7 [10527606.001]
  • [Cites] J Am Acad Dermatol. 1993 Aug;29(2 Pt 1):228-36 [8335743.001]
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  • (PMID = 19220898.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2652470
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84. Barbagelata López A, Ruibal Moldes M, Blanco Díez A, Fernández Rosado E, Ponce Díaz-Reixa JL, Novas Castro S, Lancina Martín A, González Martín M: [Cutaneous metastasis of a renal carcinoma: case report and review]. Arch Esp Urol; 2005 Apr;58(3):247-50
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  • OBJECTIVES: To report another rare case of skin metastasis from a renal adenocarcinoma, analyzing the prognostic significance, response to therapy, and clinical presentation after a bibliographic review.
  • METHODS/RESULTS: We report the case of a 65-year-old male with a cutaneous metastasis in the root of his inferior left extremity one year after right nephrectomy for a clear cell adenocarcinoma.
  • CONCLUSIONS: Skin metastases usually present as solitary cutaneous lesions of variable macroscopic features and rapid growing; the diagnosis is made by histological analysis, being excision the treatment of choice whenever possible.
  • Prognosis is better for solitary lesions appearing asynchronously with the primary tumor, and among them the longer the time after diagnosis of initial lesion they appear the better the prognosis.
  • [MeSH-major] Carcinoma, Renal Cell / secondary. Kidney Neoplasms / pathology. Skin Neoplasms / secondary

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  • (PMID = 15906619.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 9
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85. Nowicki MJ, Bishop PR, Subramony C, Wyatt-Ashmead J, May W, Crawford M: Colonic chicken-skin mucosa in children with polyps is not a preneoplastic lesion. J Pediatr Gastroenterol Nutr; 2005 Nov;41(5):600-6
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  • [Title] Colonic chicken-skin mucosa in children with polyps is not a preneoplastic lesion.
  • Chicken-skin mucosa (CSM) is an endoscopic finding initially described associated with adenomatous polyps and adenocarcinoma, suggesting a preneoplastic lesion.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenoma / diagnosis. Adenoma / metabolism. Adenoma / pathology. Biomarkers, Tumor / analysis. Biopsy. Child. Child, Preschool. Colon / pathology. Colonoscopy. Female. Humans. Immunohistochemistry. Male. Prospective Studies

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  • (PMID = 16254516.001).
  • [ISSN] 0277-2116
  • [Journal-full-title] Journal of pediatric gastroenterology and nutrition
  • [ISO-abbreviation] J. Pediatr. Gastroenterol. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53
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86. Uña E, Cuadrillero F, López-Lara F: Drug extravasation: a dreaded complication. BMJ Case Rep; 2009;2009
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  • A 62-year-old man diagnosed with a stage I lung adenocarcinoma was treated by an upper right lobectomy.
  • The diagnosis of delayed and distant docetaxel extravasation was made.
  • This reaction resolved over the next 6 weeks, leaving two areas of brownish pigmentation of the skin as the only sequelae.

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  • [Cites] Pharmacotherapy. 1999 Aug;19(8):1002-5 [10453974.001]
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  • (PMID = 21686582.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028026
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87. Conscience I, Perceau G, Le Berruyer PY, Bernard P: [Bilateral breast bacterial cellulite secondary to Streptococcus agalactiae septicemia]. Ann Dermatol Venereol; 2006 Feb;133(2):171-3
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  • Histological examination of a sigmoid polyp revealed a tubular adenocarcinoma.
  • DISCUSSION: We report the first documented case of secondary dermal-hypodermal bacterial skin infection (cellulitis) due to group B beta-hemolytic streptococcus.
  • The occurrence after colonoscopy examination, chronology of clinical features, bilaterality and positive blood cultures are arguments in favor of the secondary nature of the skin infection process.
  • [MeSH-minor] Adenocarcinoma / complications. Adenocarcinoma / surgery. Aged. Amoxicillin / administration & dosage. Amoxicillin / therapeutic use. Anti-Bacterial Agents / administration & dosage. Anti-Bacterial Agents / therapeutic use. Anti-Infective Agents / administration & dosage. Anti-Infective Agents / therapeutic use. Clavulanic Acid / administration & dosage. Clavulanic Acid / therapeutic use. Colonic Polyps / diagnosis. Colonic Polyps / surgery. Colonoscopy. Drug Therapy, Combination. Female. Humans. Metronidazole / administration & dosage. Metronidazole / therapeutic use. Rifampin / administration & dosage. Rifampin / therapeutic use. Sigmoid Neoplasms / complications. Sigmoid Neoplasms / diagnosis. Sigmoid Neoplasms / surgery. Time Factors. Treatment Outcome

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  • (PMID = 16508605.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Anti-Infective Agents; 140QMO216E / Metronidazole; 23521W1S24 / Clavulanic Acid; 804826J2HU / Amoxicillin; VJT6J7R4TR / Rifampin
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88. Devaux B, Rosenstingl S, Bardet M, Coldea L, Gatfosse M: [Abnormalities of hand skin]. Rev Med Interne; 2009 May;30(5):434-5
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  • [Title] [Abnormalities of hand skin].

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  • (PMID = 19264380.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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89. Bannur HB, Mastiholimath RD, Malur PR: Primary mucinous eccrine adenocarcinoma of the scalp: a case report. Acta Cytol; 2009 Nov-Dec;53(6):698-700
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  • [Title] Primary mucinous eccrine adenocarcinoma of the scalp: a case report.
  • BACKGROUND: Lesions of primary mucinous carcinoma of the skin present as painless, papular or nodular masses with sizes ranging from 5 mm to 120 mm.
  • Metastatic deposits from undiagnosed visceral and breast adenocarcinoma are virtually indistinguishable microscopically from sweat gland carcinoma and must be considered before a diagnosis of sweat gland carcinoma is made.
  • A diagnosis of mucinous eccrine adenocarcinoma was given.
  • CONCLUSION: Primary mucinous adenocarcinoma of the skin is a rare tumor and mimics metastatic adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Eccrine Glands / pathology. Scalp / pathology

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  • (PMID = 20014562.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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90. Bordel Gómez MT, Used Aznar MM: [Cutaneous metastases from adenocarcinoma of unknown primary site]. Actas Dermosifiliogr; 2006 Dec;97(10):662-5
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  • [Title] [Cutaneous metastases from adenocarcinoma of unknown primary site].
  • [Transliterated title] Metástasis cutáneas de adenocarcinoma de origen primario desconocido.
  • Metastases from cancer of unknown primary site may be located in the skin and subcutaneous tissue and it is the dermatologist the first in evaluating these patients.
  • We present a case of cutanoeus metastases from moderately-differentiated adenocarcinoma of unknown primary site.
  • Even though a minority of these patients will have a curable disease, the appropriate use of pathological diagnosis and selected imaging studies for an optimal management of patients with a tumor of unknown primary site should not be ignored.
  • [MeSH-major] Adenocarcinoma / secondary. Neoplasms, Unknown Primary. Skin Neoplasms / secondary
  • [MeSH-minor] Abdominal Neoplasms / blood. Abdominal Neoplasms / diagnosis. Abdominal Neoplasms / pathology. Abdominal Neoplasms / secondary. Aged. Disease Progression. Fatal Outcome. Humans. Male. Thoracic Neoplasms / blood. Thoracic Neoplasms / diagnosis. Thoracic Neoplasms / pathology. Thoracic Neoplasms / secondary

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  • (PMID = 17173831.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 17
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91. Gaertner WB, Hagerman GF, Goldberg SM, Finne CO 3rd: Perianal Paget's disease treated with wide excision and gluteal skin flap reconstruction: report of a case and review of the literature. Dis Colon Rectum; 2008 Dec;51(12):1842-5
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  • [Title] Perianal Paget's disease treated with wide excision and gluteal skin flap reconstruction: report of a case and review of the literature.
  • The condition is often associated with underlying invasive carcinoma and the prognosis is poor when underlying adenocarcinoma is present.
  • Four days after wide excision, bilateral gluteal skin flap reconstruction was performed with a temporary diverting colostomy.
  • CONCLUSION: Perianal Paget's disease continues to pose problems in diagnosis and treatment.

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  • (PMID = 18584248.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 34
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92. Dinić-Uzurov V, Lalosević V, Milosević I, Urosević I, Lalosević D, Popović S: [Current differential diagnosis of hypereosinophilic syndrome]. Med Pregl; 2007 Nov-Dec;60(11-12):581-6
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  • [Title] [Current differential diagnosis of hypereosinophilic syndrome].
  • Despite specific therapy, eosinophilia may persist for over a year after diagnosis, and decreases slowly.
  • We had two patients with clinical and histological features resembling chronic eosinophilic leukemia, and many others with T-cell lymphoma, planocellular or adenocarcinoma etc. where eosinophilia persisted DRUG-INDUCED EOSINOPHILIA: Drugs associated with eosinophilia include penicillins, tetracyclines, especially minocycline, clarithromycin, tetrazepam, mefloquine, and many, others.
  • HYPEREOSINOPHILIA WITH ORGAN DYSFUNCTION: Many severe diseases, such as sarcoidosis, Churg-Strauss syndrome, pemphigus vulgaris, eosinophilic gastrointestinal diseases, inflammatory bowel disease and many others are associated with hypereosinophilia and target organ damage, e.g. involvement of the heart, lungs, skin, or nervous tissue.
  • If the differential diagnosis of hypereosinophilia fails to resolve the etiology succesfully, the diagnosis of idiopathic HES remains.
  • [MeSH-major] Hypereosinophilic Syndrome / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Eosinophilia / diagnosis. Eosinophilia / etiology. Humans

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  • (PMID = 18666600.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia
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93. Hargis AM, Baldessari AE, Walder EJ: Intraepidermal adenocarcinoma in the perianal skin of two cats, a condition resembling human extramammary Paget's disease. Vet Dermatol; 2008 Feb;19(1):31-7
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  • [Title] Intraepidermal adenocarcinoma in the perianal skin of two cats, a condition resembling human extramammary Paget's disease.
  • In humans, mammary and extramammary Paget's disease is an uncommon to rare manifestation of intraepidermal adenocarcinoma arising from simple epithelium, usually glandular in origin.
  • This report describes two cats with lesions in perianal skin consisting of atypical intraepidermal neoplastic cells.
  • Differential diagnoses included intraepidermal adenocarcinoma, in situ squamous or basal cell carcinoma, junctional amelanotic melanoma, and epitheliotropic tumours of histiocytic or lymphocytic origin.
  • The clinical features, histological appearance, and immunohistochemical staining of the skin lesions were consistent with those described for human perianal extramammary Paget's disease.
  • To the authors' knowledge, this is the first report of an intraepidermal adenocarcinoma in a cat or other animal species.
  • [MeSH-major] Adenocarcinoma / veterinary. Cat Diseases / diagnosis. Perineum / pathology. Skin Neoplasms / veterinary
  • [MeSH-minor] Animals. Cats. Diagnosis, Differential. Female. Humans. Paget Disease, Extramammary

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  • (PMID = 18177290.001).
  • [ISSN] 0959-4493
  • [Journal-full-title] Veterinary dermatology
  • [ISO-abbreviation] Vet. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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94. Iwanski GB, Block A, Keller G, Muench J, Claus S, Fiedler W, Bokemeyer C: Esophageal squamous cell carcinoma presenting with extensive skin lesions: a case report. J Med Case Rep; 2008;2:115
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  • [Title] Esophageal squamous cell carcinoma presenting with extensive skin lesions: a case report.
  • CASE PRESENTATION: In our department, a 51-year-old man was diagnosed with ESCC after presenting with extensive disseminated skin nodules.
  • Cutaneous manifestations of esophageal neoplasia are very rare and are mainly described for esophageal adenocarcinoma (EADC).
  • Here we report a very uncommon case of extensive skin metastases of ESCC.
  • CONCLUSION: Early biopsies of suspicious skin lesions are important and should be performed in patients with unclear symptoms such as weight loss or dysphagia and especially in patients with a history of cancer, since they can reveal the existence of a distant malignant disease leading to diagnosis and prompt therapy.

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  • (PMID = 18426583.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2365965
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95. Feldman SC, Chu D, Schulder M, Pawar R, Barry M, Cho E-, Liu W-: The blood oxygen level-dependent functional MR imaging signal can be used to identify brain tumors and distinguish them from normal tissue. AJNR Am J Neuroradiol; 2009 Feb;30(2):389-95
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / metabolism. Glioma / diagnosis. Glioma / metabolism. Magnetic Resonance Imaging / methods. Oxygen / blood
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / metabolism. Adenocarcinoma / secondary. Adult. Female. Humans. Male. Melanoma / diagnosis. Melanoma / metabolism. Melanoma / secondary. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / metabolism. Meningioma / diagnosis. Meningioma / metabolism. Middle Aged. Retrospective Studies. Skin Neoplasms / pathology

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  • [ErratumIn] AJNR Am J Neuroradiol. 2009 Aug;30(7):E111. Pawar R [added]
  • (PMID = 19208905.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] S88TT14065 / Oxygen
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96. Kwatra KS, Prabhakar BR, Jain S: Oestrogen and progesterone receptors in primary mucinous carcinoma of skin. Australas J Dermatol; 2005 Nov;46(4):246-9
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  • [Title] Oestrogen and progesterone receptors in primary mucinous carcinoma of skin.
  • Fine-needle aspiration cytology and histopathological examination showed a picture of mucinous adenocarcinoma.
  • Clinical examination and systemic investigations failed to detect any primary lesion elsewhere and hence, a diagnosis of primary mucinous carcinoma of the skin was made.
  • [MeSH-major] Adenocarcinoma, Mucinous / metabolism. Adenocarcinoma, Mucinous / pathology. Receptors, Estrogen / analysis. Receptors, Progesterone / analysis. Skin Neoplasms / metabolism. Skin Neoplasms / pathology

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  • (PMID = 16197424.001).
  • [ISSN] 0004-8380
  • [Journal-full-title] The Australasian journal of dermatology
  • [ISO-abbreviation] Australas. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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97. Moslemi MK, Sadighi Gilani MA, Moslemi AA, Arabshahi A: Fournier gangrene presenting in a patient with undiagnosed rectal adenocarcinoma: a case report. Cases J; 2009;2:9136
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  • [Title] Fournier gangrene presenting in a patient with undiagnosed rectal adenocarcinoma: a case report.
  • Infection most commonly arises from the skin, urethra, or rectal regions.
  • In the course of medical and surgical treatment the presence of extensive rectal adenocarcinoma was discovered.
  • Skin grafting of necrotic areas was performed and systemic rectal cancer chemotherapy initiated after full stabilization.
  • Early diagnosis and treatment decrease the morbidity and mortality of this life threatening condition.

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  • [Cites] J Urol. 2009 May;181(5):2120-6 [19286224.001]
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  • (PMID = 20062653.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2803933
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98. Murali R, Loughman NT, McKenzie PR, Watson GF, Thompson JF, Scolyer RA: Cytological features of melanoma in exfoliative fluid specimens. J Clin Pathol; 2009 Jul;62(7):638-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Body Fluids / cytology. Melanoma / pathology. Melanoma / secondary. Skin Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Aged. Aged, 80 and over. Cytodiagnosis. Diagnosis, Differential. Diagnostic Errors. Epithelial Cells / pathology. Female. Histiocytes / pathology. Humans. Male. Middle Aged. Sensitivity and Specificity

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  • (PMID = 19561232.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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99. Matsubara J, Shimada Y, Takashima A, Takahari D, Hirashima Y, Okita NT, Nakajima TE, Kato K, Hamaguchi T, Yamada Y, Shirao K: A phase i study of bolus 5-fluorouracil and leucovorin combined with weekly paclitaxel (FLTAX) as first-line therapy for advanced gastric cancer. Jpn J Clin Oncol; 2008 Aug;38(8):540-6
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  • During the first cycle of the highest dose level (level 4), two of the six patients had DLT involving Grade 3 diarrhea and Grade 3 skin rash.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Stomach Neoplasms / drug therapy
  • [MeSH-minor] Adult. Aged. Female. Fluorouracil / administration & dosage. Humans. Leucovorin / administration & dosage. Male. Maximum Tolerated Dose. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / drug therapy. Paclitaxel / administration & dosage

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  • (PMID = 18628316.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] P88XT4IS4D / Paclitaxel; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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100. Pudroma X, Moan J, Ma LW, Iani V, Juzeniene A: A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin. Exp Dermatol; 2009 Nov;18(11):985-7
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  • [Title] A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin.
  • 5-aminolevulinic acid heptyl ester was investigated in human adenocarcinoma WiDr cells and in healthy skin of athymic nude mice in comparison with 5-aminolevulinic acid (ALA).
  • ALA heptyl ester, topically (but not systemically) applied, is a promising candidate for fluorescence diagnosis and photodynamic therapy.
  • [MeSH-major] Adenocarcinoma / drug therapy. Aminolevulinic Acid / antagonists & inhibitors. Aminolevulinic Acid / pharmacology. Photosensitizing Agents / pharmacology. Protoporphyrins / biosynthesis. Skin / drug effects. Skin Neoplasms / drug therapy

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  • (PMID = 19469901.001).
  • [ISSN] 1600-0625
  • [Journal-full-title] Experimental dermatology
  • [ISO-abbreviation] Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / 5-aminolevulinic acid heptyl ester; 0 / Photosensitizing Agents; 0 / Protoporphyrins; 553-12-8 / protoporphyrin IX; 88755TAZ87 / Aminolevulinic Acid
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