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1. Mahalingam M, Nguyen LP, Richards JE, Muzikansky A, Hoang MP: The diagnostic utility of immunohistochemistry in distinguishing primary skin adnexal carcinomas from metastatic adenocarcinoma to skin: an immunohistochemical reappraisal using cytokeratin 15, nestin, p63, D2-40, and calretinin. Mod Pathol; 2010 May;23(5):713-9
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  • [Title] The diagnostic utility of immunohistochemistry in distinguishing primary skin adnexal carcinomas from metastatic adenocarcinoma to skin: an immunohistochemical reappraisal using cytokeratin 15, nestin, p63, D2-40, and calretinin.
  • Often the distinction of primary adnexal carcinoma from metastatic adenocarcinoma to skin from breast, lung, and other sites can be a diagnostic dilemma.
  • [MeSH-major] Adenocarcinoma / secondary. Biomarkers, Tumor / metabolism. Neoplasms, Adnexal and Skin Appendage / pathology. Skin Neoplasms / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Antibodies, Monoclonal / metabolism. Antibodies, Monoclonal, Murine-Derived. Calbindin 2. Chi-Square Distribution. Diagnosis, Differential. Humans. Immunohistochemistry. Intermediate Filament Proteins / metabolism. Keratin-15 / metabolism. Nerve Tissue Proteins / metabolism. Nestin. Regression Analysis. S100 Calcium Binding Protein G / metabolism. Sensitivity and Specificity. Trans-Activators / metabolism. Transcription Factors. Tumor Suppressor Proteins / metabolism

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  • (PMID = 20190734.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / Intermediate Filament Proteins; 0 / Keratin-15; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin; 0 / S100 Calcium Binding Protein G; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 0 / monoclonal antibody D2-40
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2. Río Ramírez MT, Casado López ME, Peirón Puyal MJ, Peñas Herrero JM: [Pulmonary adenocarcinoma and Bazex syndrome (paraneoplastic acrokeratosis)]. Arch Bronconeumol; 2007 Jan;43(1):46-8
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  • [Title] [Pulmonary adenocarcinoma and Bazex syndrome (paraneoplastic acrokeratosis)].
  • [Transliterated title] Adenocarcinoma de pulmón y síndrome de Bazex (acroqueratosis paraneoplásica).
  • Bazex syndrome, or paraneoplastic acrokeratosis, is a rare psoriasis-like paraneoplastic skin disease, characterized by erythema and scaling, which is accompanied by hyperkeratotic lesions.
  • We present a case in which both pulmonary adenocarcinoma and Bazex syndrome were present.
  • [MeSH-major] Acrodermatitis / etiology. Adenocarcinoma / complications. Keratosis / etiology. Lung Neoplasms / complications. Paraneoplastic Syndromes / etiology
  • [MeSH-minor] Aged. Fatal Outcome. Foot Dermatoses / diagnosis. Foot Dermatoses / etiology. Hand Dermatoses / diagnosis. Hand Dermatoses / etiology. Humans. Lymphatic Metastasis. Male. Nail Diseases / diagnosis. Nail Diseases / etiology. Pruritus / etiology. Pulmonary Fibrosis / complications. Respiratory Insufficiency / complications. Syndrome

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  • (PMID = 17257564.001).
  • [ISSN] 0300-2896
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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3. Placer C, Elósegui JL, Irureta I, Mujika JA, Goena I, Enríquez Navascués JM: [Perineal cutaneous metastases from adenocarcinoma after surgery for colorectal cancer]. Cir Esp; 2007 Jul;82(1):41-3
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  • [Title] [Perineal cutaneous metastases from adenocarcinoma after surgery for colorectal cancer].
  • [Transliterated title] Metástasis cutánea perineal de adenocarcinoma tras cirugía de cáncer colorrectal.
  • Four months after surgery, a nodular ulcerated lesion was observed in the perineum due to metastases from adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Colorectal Neoplasms / pathology. Colorectal Neoplasms / surgery. Neoplasms, Second Primary. Perineum. Skin Neoplasms / secondary

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  • (PMID = 17580031.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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4. Park SH, Shin YM, Shin DH, Choi JS, Kim KH: Syringocystadenocarcinoma papilliferum: a case report. J Korean Med Sci; 2007 Aug;22(4):762-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Syringocystadenocarcinoma papilliferum (SCACP) is a rare form of adenocarcinoma of the skin.
  • We established the diagnosis of SCACP in the patient, and a wide excision was performed to remove the tumor.

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  • [Cites] Histopathology. 1980 Jul;4(4):445-66 [6253380.001]
  • [Cites] Ann Dermatol Venereol. 1982;109(8):685-9 [7187194.001]
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  • (PMID = 17728526.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Carrier Proteins; 0 / Glycoproteins; 0 / PIP protein, human
  • [Other-IDs] NLM/ PMC2693836
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5. Shukla P, Gupta D, Bisht SS, Pant MC: Ovarian adenocarcinoma in a young female with skin and umbilical metastasis. Indian J Med Paediatr Oncol; 2009 Oct;30(4):144-6

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  • [Title] Ovarian adenocarcinoma in a young female with skin and umbilical metastasis.
  • We report the case of ovarian carcinoma with skin and umbilical metastasis in a 30-year-old female.
  • The CT-guided fine needle aspiration cytology (FNAC) from the ovarian mass showed adenocarcinoma.
  • FNAC from the umbilical and skin metastasis also showed adenocarcinoma.

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  • (PMID = 20838558.001).
  • [ISSN] 0975-2129
  • [Journal-full-title] Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology
  • [ISO-abbreviation] Indian J Med Paediatr Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2930304
  • [Keywords] NOTNLM ; Ovarian carcinoma / skin metastasis / umbilical metastasis
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6. Kotru M, Manucha V, Singh UR: Cytologic and histologic features of primary mucinous adenocarcinoma of skin in the axilla: a case report. Acta Cytol; 2007 Jul-Aug;51(4):571-4
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  • [Title] Cytologic and histologic features of primary mucinous adenocarcinoma of skin in the axilla: a case report.
  • BACKGROUND: Primary mucinous adenocarcinoma of the skin is a rare tumor; its location in the axilla is rarer still.
  • It closely mimics metastatic adenocarcinoma histologically.
  • Fine needle aspiration cytology (FNAC) is a very useful preoperative investigation for its diagnosis; however, cytologic description is not available in the literature so far.
  • On subsequent biopsy a diagnosis of primary mucinous adenocarcinoma of the skin was made.
  • CONCLUSION: Because of the better prognosis of primary mucinous adenocarcinoma of the skin vis-a-vis metastatic adenocarcinoma; preoperative diagnosis is necessary.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Axilla / pathology. Skin Neoplasms / pathology

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  • (PMID = 17718124.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Levy G, Finkelstein A, McNiff JM: Immunohistochemical techniques to compare primary vs. metastatic mucinous carcinoma of the skin. J Cutan Pathol; 2010 Apr;37(4):411-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical techniques to compare primary vs. metastatic mucinous carcinoma of the skin.
  • BACKGROUND: Primary and metastatic mucinous carcinomas in skin are histologically indistinguishable.
  • Immunohistochemical panels help differentiate primary and metastatic adenocarcinoma of skin, but data regarding mucinous carcinoma is scant.
  • METHODS: We stained five primary mucinous carcinomas, two mucinous carcinomas metastatic to skin and five primary breast and colon mucinous carcinomas with p63, CD15, CK5/6, CK7, CK20, calponin and D2-40 to identify patterns that might differentiate primary from metastatic disease.
  • RESULTS: All cases of primary mucinous carcinoma of the skin were positive for CK7, 40% showed rare cells labeled for p63 and 20% of cases labeled focally for CK5/6.
  • The breast mucinous carcinomas metastatic to the skin were negative for all markers except CK7, although 60% of primary breast carcinomas labeled for p63.
  • [MeSH-major] Adenocarcinoma, Mucinous / metabolism. Biomarkers, Tumor / metabolism. Immunohistochemistry / methods. Skin Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Breast Neoplasms / pathology. Diagnosis, Differential. Female. Head and Neck Neoplasms / pathology. Humans. Male. Middle Aged. Scalp

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  • (PMID = 19788442.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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8. Martínez-Luna E, Puebla-Miranda M, Vega-Memije ME: [Skin metastasis of gastric adenocarcinoma. Case report]. Rev Gastroenterol Mex; 2009 Oct-Dec;74(4):362-5
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  • [Title] [Skin metastasis of gastric adenocarcinoma. Case report].
  • [Transliterated title] Metástasis cutáneas de adenocarcinoma gástrico; informe de un caso.
  • These lesions generally occur in late stages of disease, being uncommon their presentation at the time of diagnosis.
  • We inform the case of a male patient who presented a metastatic adenocarcinoma in the skin of the chest.
  • Under the suspect of primary tumor in the gastrointestinal tract, an upper gastrointestinal endoscopy was made corroborating diagnosis of a primary gastric cancer.
  • The case instructs the unusual morphology of cutaneous metastasis of gastric adenocarcinoma, as well appearing as the initial clinical data in an extended malignant disease.
  • Key words: cutaneous metastases, metastatic adenocarcinoma, gastric carcinoma, Mexico.
  • [MeSH-major] Adenocarcinoma / secondary. Skin Neoplasms / secondary. Stomach Neoplasms / pathology

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  • (PMID = 20423769.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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9. Ivan D, Nash JW, Prieto VG, Calonje E, Lyle S, Diwan AH, Lazar AJ: Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin. J Cutan Pathol; 2007 Jun;34(6):474-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin.
  • p63, a recently identified homologue of the p53 gene, is mainly expressed by basal and myoepithelial cells in skin.
  • Others and we have shown the value of p63 in distinguishing primary adnexal tumors from visceral adenocarcinomas metastatic to skin.
  • We now investigate the pattern of p63 expression in metastases from skin adnexal carcinomas and their cognate primaries and evaluate p63 expression in a larger case series of malignant cutaneous adnexal neoplasms.
  • Twenty visceral metastatic adenocarcinomas to the skin and 7 primary mucinous carcinomas with cutaneous or visceral origin were compared.
  • Analysis of p63 expression may assist in the differential diagnosis of primary adnexal carcinomas versus metastatic visceral adenocarcinomas to the skin.
  • [MeSH-major] Adenocarcinoma, Mucinous / metabolism. Biomarkers, Tumor / metabolism. DNA-Binding Proteins / metabolism. Neoplasms, Adnexal and Skin Appendage / metabolism. Skin Neoplasms / metabolism. Trans-Activators / metabolism. Tumor Suppressor Proteins / metabolism
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Immunoenzyme Techniques. Retrospective Studies. Transcription Factors

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  • [CommentIn] J Cutan Pathol. 2008 Jul;35(7):692-3 [18312438.001]
  • (PMID = 17518775.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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10. Sikorszki L, Horváth OP, Papp A, Cseke L, Pavlovics G: [Colon cancer after colon interposition for oesophageal replacement]. Magy Seb; 2010 Aug;63(4):157-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Colonnal történt nyelőcsőpótlás után kialakult vastagbél-adenocarcinoma.
  • The authors report the case of a colon adenocarcinoma developed on the neck at the anastomosis of the skin tube and colon 44 years following a corrosive oesophageal injury.
  • An antethoracal oesophagus formation was performed with ileocolon and skin tube amendment.
  • 44 years later an ulcerated adenocarcinoma developed in the transposed colon, which was resected and the ability to swallow was reinstated by the transplantation of an isolated jejunal segment using microvascular anastomosis.
  • [MeSH-major] Adenocarcinoma / surgery. Burns, Chemical / complications. Cecal Neoplasms / surgery. Colon / transplantation. Esophagectomy. Esophagus / pathology. Jejunum / transplantation

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  • (PMID = 20724239.001).
  • [ISSN] 0025-0295
  • [Journal-full-title] Magyar sebészet
  • [ISO-abbreviation] Magy Seb
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Caustics; QTT17582CB / Hydrochloric Acid
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11. Torné J, Bonaut B, Sanz C, Martínez C, Torrero MV, Miranda-Romero A: [Cutaneous metastases of rectal adenocarcinoma in a herpetiform distribution]. Actas Dermosifiliogr; 2006 Apr;97(3):206-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cutaneous metastases of rectal adenocarcinoma in a herpetiform distribution].
  • [Transliterated title] Metástasis cutáneas de adenocarcinoma de recto con distribución herpetiforme.
  • We present the case of a 62-year-old male with cutaneous metastases of a rectal adenocarcinoma located on the groin and left thigh.
  • They may mimic benign skin lesions like epidermoid cysts, lipomas, erysipelas or, as in our case, herpes zoster.
  • [MeSH-major] Carcinoma, Signet Ring Cell / secondary. Diagnostic Errors. Rectal Neoplasms / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Anemia / etiology. Diarrhea / etiology. Groin. Herpes Zoster / diagnosis. Humans. Male. Middle Aged. Thigh

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  • (PMID = 16796970.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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12. Guzman Martinez-Valls PL, Rodríguez Tardido A, Honrubia Vilchez B, Izquierdo Morejon E, Pietricica BN, Montoya Chinchilla R, Rosino Sanchez A, Hita Villaplana G, Romero Hoyuela A, Miñana Lopez B: [Frontal mass simulating lipoma as a clinical presentation of prostatic adenocarcinoma]. Arch Esp Urol; 2009 Jan-Feb;62(1):66-9
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  • [Title] [Frontal mass simulating lipoma as a clinical presentation of prostatic adenocarcinoma].
  • [Transliterated title] Bultoma frontal simulando lipoma como manifestación de adenocarcinoma de próstata.
  • METHODS: We describe the debut in a patient, who thanks to the pathologic analysis of a lesion mimicking a lipoma, which was reported as adenocarcinoma, was worked up for prostatic adenocarcinoma and diagnosis was reached.
  • CONCLUSIONS: Cutaneous metastases of prostatic adenocarcinoma are very rare, but even rarer is it being the debut of the disease.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / secondary. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / secondary. Lipoma / diagnosis. Prostatic Neoplasms / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / secondary
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male


13. Bordel Gómez MT, Used Aznar MM: [Cutaneous metastases from adenocarcinoma of unknown primary site]. Actas Dermosifiliogr; 2006 Dec;97(10):662-5
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  • [Title] [Cutaneous metastases from adenocarcinoma of unknown primary site].
  • [Transliterated title] Metástasis cutáneas de adenocarcinoma de origen primario desconocido.
  • Metastases from cancer of unknown primary site may be located in the skin and subcutaneous tissue and it is the dermatologist the first in evaluating these patients.
  • We present a case of cutanoeus metastases from moderately-differentiated adenocarcinoma of unknown primary site.
  • Even though a minority of these patients will have a curable disease, the appropriate use of pathological diagnosis and selected imaging studies for an optimal management of patients with a tumor of unknown primary site should not be ignored.
  • [MeSH-major] Adenocarcinoma / secondary. Neoplasms, Unknown Primary. Skin Neoplasms / secondary
  • [MeSH-minor] Abdominal Neoplasms / blood. Abdominal Neoplasms / diagnosis. Abdominal Neoplasms / pathology. Abdominal Neoplasms / secondary. Aged. Disease Progression. Fatal Outcome. Humans. Male. Thoracic Neoplasms / blood. Thoracic Neoplasms / diagnosis. Thoracic Neoplasms / pathology. Thoracic Neoplasms / secondary

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  • (PMID = 17173831.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 17
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14. De Vita F, Orditura M, Innocente R, Vecchione L, Pinto C, Chiarion Sileni V, Martinelli E, Ruol A, Catalano G, Ciardiello F: A multicenter phase II study of induction CT with FOLFOX-4 and cetuximab followed by RT and cetuximab in locally advanced esophageal cancer (LAEC). J Clin Oncol; 2009 May 20;27(15_suppl):4546

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Eligibility criteria: resectable, locally advanced (uT3 or uN1, T4 if deemed resectable) squamous cell carcinoma (SCC) or adenocarcinoma (AC) of the esophagus; staged by EUS, CT and PET scan; age 18-70y; PS <2; normal organ functions.All pts received induction treatment with C at a starting dose of 400 mg/m<sup>2</sup> and further weekly infusion at a maintenance dose of 250 mg/m<sup>2</sup> and 4 cycles of FOLFOX-4 every two weeks.
  • The most frequent grade 3/4 toxicity of chemoradiotherapy were skin (32%),neutropenia (29%) and esophagitis (9%); 10 pts had no resection (9 progressive disease,1 patient's refusal).

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  • (PMID = 27963011.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Lind JS, Dingemans AC, Groen HJ, Smit EF: A phase II study of erlotinib and sorafenib in chemotherapy-naive patients with locally advanced/metastatic non-small cell lung cancer (NSCLC). J Clin Oncol; 2009 May 20;27(15_suppl):8018

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: 50 pts were enrolled: 22 females; median age 60 yrs (range 41-78); 30 PS 0; 37 stage IV; 34 adenocarcinoma; 11 never smokers; 10/33 EGFR mutations (exons 19 (n=5), 20 (n=1), 21 (n=4)); 3/33 K-Ras mutations.
  • Grade ≥ 3 AE: anorexia (n=1), acneiform rash (n=5), diarrhoea (n=6), fatigue (n=4), hand-foot skin reaction (n=6), nausea (n=2), oral mucositis (n=2), rash (n=5), vomiting (n=1) and fatal hemoptysis (n=1).

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  • (PMID = 27962809.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Govindan R, Bogart J, Wang X, Hodgson L, Kratzke R, Vokes EE, Cancer and Leukemia Group B: Phase II study of pemetrexed, carboplatin, and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small cell lung cancer: CALGB 30407. J Clin Oncol; 2009 May 20;27(15_suppl):7505

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common histological type was adenocarcinoma (46% in Arm A and 41% in Arm B).
  • Updated toxicity data (grade 3 or greater, %) by arms (arm A/arm B) for 106 pts: neutropenia 40/47; febrile neutropenia 8/6, thrombocytopenia 36/34, nausea/vomiting 8/10, esophagitis 32/24, skin rash 2/21 and fatigue 22/17.

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  • (PMID = 27963475.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Ebi N, Semba H, Tokunaga S, Takayama K, Wataya H, Kuraki T, Yamamoto H, Akamine S, Okamoto I, Nakanishi Y, Lung Oncology Group in Kyushu (LOGIK): Safety and efficacy of gefitinib monotherapy for patients (pts) ≥80 years (yrs) with advanced non-small cell lung cancer (NSCLC): A phase II subset analysis. J Clin Oncol; 2009 May 20;27(15_suppl):e19059

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e19059 Background: Lung cancer is a disease of the elderly with median age at diagnosis of 70 yrs.
  • Patient characteristics: male/female = 12/16, median age = 82 (range 80-90), ECOG PS 0/1/2=7/13/8, stage IB/IIIA/IV=1/3/24, and adenocarcinoma (Ad)/non-Ad= 22/6.
  • The most frequent adverse events were skin disorders (86%).

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  • (PMID = 27962159.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Cardona Zorrilla AF, Moran T, Reguart N, Porta R, Queralt C, Cardenal F, Carrasco-Chaumel E, Massuti B, Taron M, Rosell R: Characteristics and outcomes of non-small cell lung cancer (NSCLC) patients (pts) carrying epidermal growth factor receptor (EGFR) mutations who progress after initial erlotinib (E) response. J Clin Oncol; 2009 May 20;27(15_suppl):8064

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Pts mean age was 59±12.5 years; 65% females; 94% never-smokers; 54 adenocarcinoma.
  • There were no differences in TTP according to gender (p = 0.10), type of mutation (p = 0.63) or severity of skin toxicity (p = 0.16).

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  • (PMID = 27962639.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Woell E, Greil R, Eisterer W, Fridrik M, Grünberger B, Zabernigg A, Mayrbäurl B, Russ G, Thaler J: Oxaliplatin, irinotecan, and cetuximab in advanced gastric cancer. First efficacy results of a multicenter phase II trial (AGMT Gastric-2) of the Arbeitsgemeinschaft Medikamentoese Tumortherapie (AGMT). J Clin Oncol; 2009 May 20;27(15_suppl):4538

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 51 patients with histological proven unresectable and/or metastatic gastric adenocarcinoma were treated in a first line setting.
  • Acneiform skin rash grade 1 / 2 / 3 / 4 was reported in 31% / 20% / 6% / 2% of pts. respectively.

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  • (PMID = 27962987.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Yuan Y, Ma H, Cohen DJ, Ryan T, Choi H, Love' E, Awad M, Khambata-Ford S, Mauro D, Hochster H: Activity and tolerance of biweekly CapeOx-cetuximab in 1st line therapy of metastatic colorectal cancer (mCRC): Relation to K-ras mutation status. J Clin Oncol; 2009 May 20;27(15_suppl):e15018

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Pts with previously untreated, histologically confirmed, metastatic colon adenocarcinoma, ECOG PS 0-1, and adequate organ function were eligible.
  • Grade 0-1 vs. 2-3 skin rash was 33% vs. 67% for WT and.

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  • (PMID = 27964423.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Cobo M, Martinez J, Montesa A, Gil-Calle S, Villar-Chamorro E, Ales I, Gutierrez V, Durán G, Carabantes-Ocón F, Benavides M: Phase II trial of erlotinib maintenance therapy after platinun-based chemotherapy in advanced non-small cell lung cancer (NSCLC). J Clin Oncol; 2009 May 20;27(15_suppl):e19013

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • HISTOLOGY: adenocarcinoma 8(61.7%), bronquioloalveolar 3(6.4%), large cell 3(6.4%), squamous12(25.5%).
  • TOXICITY: The most frequent was skin rash, grade (g) 1 in 11(23.4%), g 2: 16(34%) and g 3: 3(6.4%).
  • We found a significant benefit in p with g 2-3 skin toxicity respect g 0-1, in both TTP( p= 0.0003) and OS (p= 0.0014).
  • Pts with the best benefit were those with response to erlotinib, in never or past (> 5 years) smokers and with g 2-3 skin toxicity.

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  • (PMID = 27962630.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Kristeleit R, Calvert H, Arkenau H, Olmos D, Adam J, Plummer ER, Lock V, Squires M, Fazal L, Judson I: A phase I study of AT9283, an aurora kinase inhibitor, in patients with refractory solid tumors. J Clin Oncol; 2009 May 20;27(15_suppl):2566

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Biological evidence of aurora B inhibition manifest as a reduction in histone H3 phosphorylation in skin biopsies during the infusion was observed at all dose levels.
  • An additional 4 patients received at least six cycles of therapy (squamous cell carcinoma of the lung, adenocarcinoma of the esophagus and colorectal carcinoma [2]) with a best response of stable disease.

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  • (PMID = 27961883.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Han J, Lee S, Yun T, Moon Y, Park I, Kim H, Lee J: Randomized phase II study of gefitinib alone or with simvastatin in previously treated advanced non-small cell lung cancer (NSCLC). J Clin Oncol; 2009 May 20;27(15_suppl):8057

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Between May 2006 and September 2008, 107 patients (51% male, 74% adenocarcinoma, 50% never-smoker, 54% more than two prior regimens) were randomly assigned to gefitinib alone (250 mg/d orally, n=53) or gefitinib plus simvastatin (250mg/d and 40 mg/d orally, respectively, n=54).
  • In subgroup analysis, gefitinib plus simvastatin showed a trend for higher RR than gefitinib alone in non-adenocarcinoma group (38.5% vs. 7.7%, p=0.08).
  • Adverse events at both arms were generally mild (grade 1 or 2) and consisted mainly of skin reactions.
  • CONCLUSIONS: Gefitinib combined with simvastatin did not improved efficacy compared to gefitinib alone in this unselected patient population, but showed a trend for higher efficacy in non-adenocarcinoma patients.

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  • (PMID = 27962643.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Janne PA, Reckamp K, Koczywas M, Engelman JA, Camidge DR, Rajan A, Khuri F, Liang JQ, O'Connell J, Giaccone G: Efficacy and safety of PF-00299804 (PF299) in patients (pt) with advanced NSCLC after failure of at least one prior chemotherapy regimen and prior treatment with erlotinib (E): A two-arm, phase II trial. J Clin Oncol; 2009 May 20;27(15_suppl):8063

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Pts were enrolled by histology: adenocarcinoma (Arm A) and non-adenocarcinoma (Arm B), and received PF299 45 mg QD.
  • The most common treatment-related AEs were skin and gastrointestinal disorders, with grade 3 AEs in 19% and 13% of pts, respectively.
  • At submission, enrollment in the adenocarcinoma arm is complete and enrollment in the non-adenocarcinoma arm continues; updated efficacy data and tumor characterization will be presented.

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  • (PMID = 27962636.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Uronis HE, Bullock K, Blobe G, Hsu S, Morse M, Nixon A, Haley S, O'Neill M, Hurwitz H, Bendell J: A phase I study of gemcitabine plus dasatinib (GD) or gemcitabine plus dasatinib plus cetuximab (GDC) in refractory solid tumors. J Clin Oncol; 2009 May 20;27(15_suppl):e15506

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Serum, plasma, and skin biopsy biomarkers were obtained pre- and on treatment.
  • RESULTS: 25 pts have been enrolled, including 21 with pancreatic adenocarcinoma, 3 of whom had received prior G. 21 pts were evaluable for toxicity and 18 for efficacy.

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  • (PMID = 27962236.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Shih J, Yang C, Su W, Hsia T, Tsai C, Chen Y, Chang H, Terlizzi E, Shahidi M, Miller VA: A phase II study of BIBW 2992, a novel irreversible dual EGFR and HER2 tyrosine kinase inhibitor (TKI), in patients with adenocarcinoma of the lung and activating EGFR mutations after failure of one line of chemotherapy (LUX-Lung 2). J Clin Oncol; 2009 May 20;27(15_suppl):8013

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A phase II study of BIBW 2992, a novel irreversible dual EGFR and HER2 tyrosine kinase inhibitor (TKI), in patients with adenocarcinoma of the lung and activating EGFR mutations after failure of one line of chemotherapy (LUX-Lung 2).
  • Eligible pts have stage IIIB/IV lung adenocarcinoma, EGFR mutation in exons 18-21 (tested by direct sequencing), measurable disease, ECOG PS 0-2 and adequate end organ function.
  • Most common related AEs were diarrhea and skin-related AEs, reported in 87% and 88% of pts, respectively.
  • Diarrhea and skin disorders, the most frequently observed AEs, are manageable with supportive care and dose reduction.

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  • (PMID = 27962806.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Dragnev KH, Cyrus JC, Rigas JR, DiSalvo WM, Dmitrovsky E: Association between triglyceride (TG) levels, other clinical characteristics, and outcomes in patients with advanced non-small cell lung cancer (NSCLC) treated with erlotinib and bexarotene. J Clin Oncol; 2009 May 20;27(15_suppl):8101

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The appearance of skin rash was documented.
  • RESULTS: Sixty-one pts with stage IV NSCLC were enrolled, 54% women and 72% with adenocarcinoma, 15% never smokers, 20% current smokers, 15% had prior anti-EGFR therapy.

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  • (PMID = 27964276.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Kanzler S, Trarbach T, Seufferlein T, Kubicka S, Lordick F, Geissler M, Daum S, Galle PR, Moehler M, German Arbeitsgemeinschaft Internistische Onkologie (AIO): Cetuximab with irinotecan/folinic acid/5-FU as first-line treatment in advanced gastric cancer: A nonrandomized multicenter AIO phase II study. J Clin Oncol; 2009 May 20;27(15_suppl):4534

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Patients (pts) were eligible with untreated adenocarcinoma of the stomach or oesophagogastric junction, with ECOG performance status (PS) < 2, measurable lesions and adequate organ functions.
  • Grade 3/4 toxicities were diarrhoea (17% pts), skin reactions (13% pts), anorexia (9% pts), anaemia and fatigue (7%pts), allergic reactions, leucopoenia and neutropenia (4% pts each).

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  • (PMID = 27962992.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Akinci M, Salan A, Cetin B, Aslan S: Primary mucinous eccrine adenocarcinoma of the skin in a 69-year-old man. Chirurgia (Bucur); 2010 Jan-Feb;105(1):109-11

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mucinous eccrine adenocarcinoma of the skin in a 69-year-old man.
  • The authors report a rare case of primary mucinous eccrine adenocarcinoma of the skin initially diagnosed as metastatic adenocarcinoma and treated with local excision and adjuvant radiotherapy in another center.
  • Diagnosis in our center was primary cutaneous eccrine mucinous adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Axilla / pathology. Eccrine Glands / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 20405690.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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30. Bannur HB, Mastiholimath RD, Malur PR: Primary mucinous eccrine adenocarcinoma of the scalp: a case report. Acta Cytol; 2009 Nov-Dec;53(6):698-700

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mucinous eccrine adenocarcinoma of the scalp: a case report.
  • BACKGROUND: Lesions of primary mucinous carcinoma of the skin present as painless, papular or nodular masses with sizes ranging from 5 mm to 120 mm.
  • Metastatic deposits from undiagnosed visceral and breast adenocarcinoma are virtually indistinguishable microscopically from sweat gland carcinoma and must be considered before a diagnosis of sweat gland carcinoma is made.
  • A diagnosis of mucinous eccrine adenocarcinoma was given.
  • CONCLUSION: Primary mucinous adenocarcinoma of the skin is a rare tumor and mimics metastatic adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Eccrine Glands / pathology. Scalp / pathology

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  • (PMID = 20014562.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Añibarro Laca E, Pérez-Irezabal Pindado JC, Ibáñez Calle T, Llarena Ibarguren R: [Metastases from a rectal adenocarcinoma to the prepuce]. Arch Esp Urol; 2006 Sep;59(7):737-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Metastases from a rectal adenocarcinoma to the prepuce].
  • [Transliterated title] Metastasis subcutáneas en prepucio secundarias a adenocarcinoma de recto.
  • OBJECTIVE: We report one case of metastatic dissemination of a rectal adenocarcinoma to the prepuce.
  • METHODS: 61-year-old patient with the diagnosis of rectal adenocarcinoma treated 18 months before by surgery and chemotherapy.
  • He presents with a painful enlargement of the penis associated with outgrowing erythematous lesions in the skin of the prepuce that bled on touch and did not allow the vision of the meatus and the glans penis.
  • RESULTS: The pathologic study reported a moderately differentiated intestinal type adenocarcinoma with high mitotic index infiltrating the squamous cell flat epithelium of the prepuce.
  • [MeSH-major] Adenocarcinoma / secondary. Penile Neoplasms / secondary. Rectal Neoplasms / pathology

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  • [CommentIn] Arch Esp Urol. 2006 Nov;59(9):926; author reply 927 [17190224.001]
  • (PMID = 17078400.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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32. Pozdnyakova O, Hoang MM, Dresser KA, Mahalingam M: Prognostic value of E-cadherin, beta-catenin, CD44v6, and HER2/neu in metastatic cutaneous adenocarcinoma. Arch Pathol Lab Med; 2009 Aug;133(8):1285-90
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic value of E-cadherin, beta-catenin, CD44v6, and HER2/neu in metastatic cutaneous adenocarcinoma.
  • CONTEXT: Our recent experience with a patient developing cutaneous metastases within 3 months of diagnosis of esophageal adenocarcinoma suggests that altered expression of the cellular adhesion molecules, E-cadherin and CD44v6, may have had a role to play in the rapid onset of metastases.
  • DESIGN: E-cadherin, beta-catenin, CD44v6, and HER2/neu immunohistochemical stains were performed on archival materials of metastatic adenocarcinoma to the skin from 27 patients and the available corresponding primary tumors in 10 patients.
  • [MeSH-major] Adenocarcinoma / metabolism. Biomarkers, Tumor / metabolism. Esophageal Neoplasms / metabolism. Neoplasm Proteins / metabolism. Skin Neoplasms / metabolism

  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 19653727.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers, Tumor; 0 / CD44v6 antigen; 0 / Cadherins; 0 / Neoplasm Proteins; 0 / beta Catenin; EC 2.7.10.1 / Receptor, ErbB-2
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33. Fereidooni F, Kovacs K, Azizi MR, Nikoo M: Skin metastasis from an occult esophageal adenocarcinoma. Can J Gastroenterol; 2005 Nov;19(11):673-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Skin metastasis from an occult esophageal adenocarcinoma.
  • Metastases to the skin from carcinoma arising in other organs are uncommon, yet they may be the first presentation of neoplastic disease.
  • Skin metastases from esophageal adenocarcinoma are extremely rare.
  • A unique case of an otherwise healthy patient who presented with a small, painless, mobile, clinically localized facial skin nodule is reported.
  • A biopsy revealed metastatic adenocarcinoma, and subsequent investigations detected the primary tumour in the esophagus, despite no symptoms.
  • [MeSH-major] Adenocarcinoma / secondary. Esophageal Neoplasms / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 16292362.001).
  • [ISSN] 0835-7900
  • [Journal-full-title] Canadian journal of gastroenterology = Journal canadien de gastroenterologie
  • [ISO-abbreviation] Can. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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34. Vilbergsson E, Isaksson HJ, Möller PH: [Case report: facial skin metastasis from rectal adenocarcinoma]. Laeknabladid; 2010 Feb;96(2):109-10
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Case report: facial skin metastasis from rectal adenocarcinoma].
  • Biopsy showed signetring cell adenocarcinoma.
  • During hospital stay a skin lesion of the face was removed at the request of the patient.
  • Biopsy showed metastatic signetring adenocarcinoma.
  • Colorectal metastatic lesions to the skin are rare findings, especially metastasis to the face.
  • Skin examination in patients with suspected or known malignancies is an important part of the clinical examination.
  • Key words: Rectal cancer, metastases, skin.
  • [MeSH-major] Carcinoma, Signet Ring Cell / secondary. Facial Neoplasms / secondary. Rectal Neoplasms / pathology. Skin Neoplasms / secondary

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  • (PMID = 20118505.001).
  • [ISSN] 0023-7213
  • [Journal-full-title] Læknablađiđ
  • [ISO-abbreviation] Laeknabladid
  • [Language] ice
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Iceland
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35. Ambro CM, Humphreys TR, Lee JB: Epidermotropically metastatic pancreatic adenocarcinoma. Am J Dermatopathol; 2006 Feb;28(1):60-2
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidermotropically metastatic pancreatic adenocarcinoma.
  • We describe an epidermotropically metastatic pancreatic mucinous ductal adenocarcinoma on the scalp.
  • The patient's history of pancreatic mucinous ductal adenocarcinoma and immunohistochemical staining pattern of carbohydrate antigen 19-9 (CA 19-9) confirmed the diagnosis.
  • [MeSH-major] Adenocarcinoma, Mucinous / secondary. Carcinoma, Pancreatic Ductal / secondary. Pancreatic Neoplasms / pathology. Skin Neoplasms / secondary

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  • (PMID = 16456328.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-19-9 Antigen
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36. López-Tarruella Cobo S, Moreno Antón F, Sastre J, López García-Asenjo JA, Torres A, Díaz-Rubio E: Cuirasse skin metastases secondary to gastric adenocarcinoma. Clin Transl Oncol; 2005 Jun;7(5):213-5
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cuirasse skin metastases secondary to gastric adenocarcinoma.
  • Skin metastases are infrequent manifestations of solid tumours.
  • Skin metastases from gastric adenocarcinomas are particularly rare, and represent 6% of the total in males and 1% in females.
  • We report, here, the case of a patient diagnosed with gastric adenocarcinoma with extensive subcutaneous infiltration of the abdominal wall, resulting in an abdominal cuirass.
  • [MeSH-major] Adenocarcinoma / secondary. Skin Neoplasms / secondary. Stomach Neoplasms / pathology
  • [MeSH-minor] Female. Humans. Middle Aged. Skin / pathology

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  • (PMID = 15960933.001).
  • [ISSN] 1699-048X
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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37. Zhao YY, Zhang Y, Zhao HY, Wu JX, Jiang W, Xue C, Zhang L: [Predictive factors for response and survival of gefitinib-treated locally advanced or metastatic non-small cell lung cancer patients: a retrospective analysis of two phase II clinical trials]. Ai Zheng; 2009 Jun;28(6):626-31
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenocarcinoma and skin rash were associated with better response.
  • CONCLUSIONS: Adenocarcinoma and skin rash are predictors of better response to gefitinib.
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / pathology. Adult. Aged. Aged, 80 and over. Clinical Trials, Phase II as Topic. Disease Progression. Exanthema / chemically induced. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Staging. Remission Induction. Retrospective Studies. Survival Rate. Young Adult


38. Kim ES, Lee DP, Lee MW, Choi JH, Moon KC, Koh JK: Cutaneous metastasis of uterine papillary serous carcinoma. Am J Dermatopathol; 2005 Oct;27(5):436-8
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  • Uterine papillary serous carcinoma (UPSC) is an uncommon highly malignant variant of endometrial adenocarcinoma that histologically and clinically resembles papillary serous carcinoma of the ovary.
  • A 54-year-old Korean female developed multiple pruritic skin nodules on the pubic area 13 months later after diagnosis of uterine papillary serous carcinoma.
  • A biopsy of the skin lesions showed papillary serous carcinoma, compatible with her primary tumor.
  • Without clinical history, it is difficult to distinguish other types of metastatic carcinoma to the skin and primary apocrine carcinoma of the skin from metastatic uterine papillary serous carcinoma.
  • Whereas uterine papillary serous carcinoma only rarely involves the skin, this entity should be included in the differential diagnosis of papillary adenocarcinoma in the skin.
  • [MeSH-major] Cystadenocarcinoma, Papillary / secondary. Skin Neoplasms / secondary. Uterine Neoplasms / pathology

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  • (PMID = 16148416.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Adyanthaya R: Multiple cutaneous metastases from esophageal adenocarcinoma. J Gastrointest Cancer; 2008;39(1-4):22-5
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  • [Title] Multiple cutaneous metastases from esophageal adenocarcinoma.
  • [corrected] We describe an extremely rare case of multiple cutaneous metastases from esophageal adenocarcinoma.
  • CASE REPORT: A month before the patient came to us, he had presented to the ER for evaluation of skin lesions and was sent home on a 1-week course of oral antibiotics.
  • He later presented with dysphagia and was diagnosed with esophageal adenocarcinoma and biopsy of the skin lesions revealed metastases.
  • DISCUSSION: This report stresses the importance that newly appearing skin lesions may be the first presentation of esophageal carcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / secondary. Esophageal Neoplasms / pathology. Skin Neoplasms / secondary

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  • [ErratumIn] J Gastrointest Cancer. 2008;39(1-4):159
  • (PMID = 19333791.001).
  • [ISSN] 1941-6628
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Durairaj VD, Hink EM, Kahook MY, Hawes MJ, Paniker PU, Esmaeli B: Mucinous eccrine adenocarcinoma of the periocular region. Ophthal Plast Reconstr Surg; 2006 Jan-Feb;22(1):30-5
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  • [Title] Mucinous eccrine adenocarcinoma of the periocular region.
  • PURPOSE: To report 4 patients with mucinous eccrine adenocarcinoma of the periocular region.
  • METHODS: Interventional case series of 4 patients with mucinous eccrine adenocarcinoma of the periocular region treated at 2 centers.
  • RESULTS: Two patients with mucinous eccrine adenocarcinoma of the upper eyelid, 1 with mucinous eccrine adenocarcinoma of the lower eyelid, and 1 with mucinous eccrine adenocarcinoma of the eyebrow were included in this report.
  • CONCLUSIONS: Mucinous eccrine adenocarcinoma is a rare ocular adnexal neoplasm that can involve the eyelid and periocular skin, can be locally invasive, and has a high risk of local recurrence despite Mohs surgery.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Eyelid Neoplasms / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Middle Aged. Mohs Surgery / methods. Radiotherapy, Adjuvant

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  • (PMID = 16418662.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Roh EK, Nord R, Jukic DM: Scalp metastasis from esophageal adenocarcinoma. Cutis; 2006 Feb;77(2):106-8
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  • [Title] Scalp metastasis from esophageal adenocarcinoma.
  • There are few reported cases of cutaneous metastases of esophageal carcinoma, especially of esophageal adenocarcinoma, but reports may become more common as the incidence of esophageal cancer increases.
  • [MeSH-major] Adenocarcinoma / pathology. Esophageal Neoplasms / pathology. Scalp / pathology. Skin Neoplasms / secondary

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  • (PMID = 16570673.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Warchoł R, Szymański L, Seichter A: [Rectal adenocarcinoma metastasis to the facial skin--case report]. Otolaryngol Pol; 2008;62(1):96-9
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  • [Title] [Rectal adenocarcinoma metastasis to the facial skin--case report].
  • Histopatological examination of specimen from the facial skin lesion revealed adenocarcinoma cells.
  • RESULTS AND CONCLUSIONS: We present this case report as an example of an unusual and rare secondary malignancy of head and neck, emphasizing the interdisciplinary character of oncological treatment and the role of oncological vigilance on every step of diagnosis.
  • [MeSH-major] Adenocarcinoma / secondary. Facial Neoplasms / secondary. Rectal Neoplasms / pathology. Skin Neoplasms / secondary

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  • (PMID = 18637429.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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43. Mebazaa A, Chouk S, Azzouz H, El Euch D, Rouhou RC, Trojjet S, Mokni M, Zitouna M, Ben Osman A: Leukocytoclastic vasculitis and gastric adenocarcinoma. Acta Dermatovenerol Alp Pannonica Adriat; 2010;19(1):21-3
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  • [Title] Leukocytoclastic vasculitis and gastric adenocarcinoma.
  • We report a case of cutaneous leucocytoclastic vasculitis that revealed a gastric adenocarcinoma.
  • A skin biopsy noted typical leucocytoclastic vasculitis.
  • A workup including GI tract investigations revealed an antral adenocarcinoma.
  • Complete excision of the gastric tumor was followed by resolution of the skin lesions.
  • [MeSH-major] Adenocarcinoma / complications. Stomach Neoplasms / complications. Vasculitis, Leukocytoclastic, Cutaneous / etiology. Vasculitis, Leukocytoclastic, Cutaneous / pathology

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  • (PMID = 20372770.001).
  • [ISSN] 1581-2979
  • [Journal-full-title] Acta dermatovenerologica Alpina, Pannonica, et Adriatica
  • [ISO-abbreviation] Acta Dermatovenerol Alp Pannonica Adriat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Slovenia
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44. Hargis AM, Baldessari AE, Walder EJ: Intraepidermal adenocarcinoma in the perianal skin of two cats, a condition resembling human extramammary Paget's disease. Vet Dermatol; 2008 Feb;19(1):31-7
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  • [Title] Intraepidermal adenocarcinoma in the perianal skin of two cats, a condition resembling human extramammary Paget's disease.
  • In humans, mammary and extramammary Paget's disease is an uncommon to rare manifestation of intraepidermal adenocarcinoma arising from simple epithelium, usually glandular in origin.
  • This report describes two cats with lesions in perianal skin consisting of atypical intraepidermal neoplastic cells.
  • Differential diagnoses included intraepidermal adenocarcinoma, in situ squamous or basal cell carcinoma, junctional amelanotic melanoma, and epitheliotropic tumours of histiocytic or lymphocytic origin.
  • The clinical features, histological appearance, and immunohistochemical staining of the skin lesions were consistent with those described for human perianal extramammary Paget's disease.
  • To the authors' knowledge, this is the first report of an intraepidermal adenocarcinoma in a cat or other animal species.
  • [MeSH-major] Adenocarcinoma / veterinary. Cat Diseases / diagnosis. Perineum / pathology. Skin Neoplasms / veterinary
  • [MeSH-minor] Animals. Cats. Diagnosis, Differential. Female. Humans. Paget Disease, Extramammary

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  • (PMID = 18177290.001).
  • [ISSN] 0959-4493
  • [Journal-full-title] Veterinary dermatology
  • [ISO-abbreviation] Vet. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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45. Hunter JB, Smith RV, Brandwein-Gensler M: Low-grade papillary adenocarcinoma of the palate: the significance of distinguishing it from polymorphous low-grade adenocarcinoma. Head Neck Pathol; 2008 Dec;2(4):316-23
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  • [Title] Low-grade papillary adenocarcinoma of the palate: the significance of distinguishing it from polymorphous low-grade adenocarcinoma.
  • Low-grade papillary adenocarcinoma (LGPA) represents a relatively rare histological variant of polymorphous low-grade adenocarcinoma (PLGA).
  • [MeSH-major] Adenocarcinoma, Papillary / diagnosis. Palatal Neoplasms / diagnosis. Palate, Hard / pathology
  • [MeSH-minor] Combined Modality Therapy. Humans. Male. Middle Aged. Scalp / pathology. Skin Neoplasms / secondary. Skin Neoplasms / surgery

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  • (PMID = 20614302.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2807587
  • [Keywords] NOTNLM ; Low-grade papillary adenocarcinoma / Oral salivary gland tumor / Polymorphous low-grade adenocarcinoma
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46. Rubegni P, Poggiali S, De Santi M, Marsili S, Bilenchi R, Miracco C, Fimiani M: Cutaneous metastases from adenocarcinoma of the rete testis. J Cutan Pathol; 2006 Feb;33(2):181-4
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  • [Title] Cutaneous metastases from adenocarcinoma of the rete testis.
  • Adenocarcinoma of the rete testis (ACRT) is extremely rare and has only been the subject of sporadic case reports, in most of which the neoplasm manifested as a scrotal mass with diffuse enlargement of the testis.
  • To our knowledge, none have reported distant skin metastases.
  • We report a case of ACRT presenting with suprapubic skin metastases.
  • The diagnosis was based on clinical and histopathological findings and supported by the results of immunohistochemical and ultrastructural studies.
  • We discuss the differential diagnosis to this rare entity, which include metastatic adenocarcinoma, serous tumor of the testis, and mesothelioma of the tunica vaginalis.
  • [MeSH-major] Adenocarcinoma / secondary. Rete Testis / pathology. Skin Neoplasms / secondary. Testicular Neoplasms / pathology

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  • (PMID = 16420316.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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47. Nebesio CL, Goulet RJ Jr, Helft PR, Billings SD: Metastatic esophageal carcinoma masquerading as inflammatory breast carcinoma. Int J Dermatol; 2007 Mar;46(3):303-5
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  • A 50-year-old Caucasian woman with a history of esophageal adenocarcinoma presented with a 3-week history of right breast swelling and progressive erythema.
  • Twenty-two months prior to presentation, she had been diagnosed with adenocarcinoma of the esophagus (T3,N1,M1a) and underwent neoadjuvant chemoradiotherapy followed by surgical resection.
  • A punch biopsy revealed a poorly differentiated adenocarcinoma with extensive involvement of dermal lymphatics (Fig. 2).
  • The clinical and histologic differential diagnosis included inflammatory breast carcinoma vs. metastatic esophageal adenocarcinoma to the skin of the breast.
  • 3), confirming the diagnosis of metastatic esophageal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Breast Neoplasms / pathology. Breast Neoplasms / secondary. Esophageal Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 17343591.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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48. Al-Niaimi F, Lyon CC: Primary adenocarcinoma in peristomal skin: a case study. Ostomy Wound Manage; 2010 Jan 1;56(1):45-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary adenocarcinoma in peristomal skin: a case study.
  • Primary adenocarcinoma at an ileostomy site is an exceedingly rare occurrence but has been documented at the peristomal skin of patients with a long-standing ileostomy.
  • Biopsy of newly developing lesions in the peristomal area of long-standing stomas is essential in order to avoid delayed diagnosis and limit complications.
  • A biopsy showed evidence of primary adenocarcinoma arising from the ileostomy site.
  • [MeSH-major] Adenocarcinoma / complications. Colitis, Ulcerative / surgery. Ileostomy / adverse effects. Skin Neoplasms / complications

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  • (PMID = 20093717.001).
  • [ISSN] 1943-2720
  • [Journal-full-title] Ostomy/wound management
  • [ISO-abbreviation] Ostomy Wound Manage
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Kavgaci H, Reis A, Ozdemir F, Bektas O, Arslan M, Aydin F: Carcinoma erysipelatoides resulting from gastric adenocarcinoma: an unusual clinical presentation. Med Princ Pract; 2005 Jan-Feb;14(1):61-3
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  • [Title] Carcinoma erysipelatoides resulting from gastric adenocarcinoma: an unusual clinical presentation.
  • OBJECTIVE: To report a rare case of carcinoma erysipelatoides on the laryngeal skin caused by stomach adenocarcinoma.
  • CLINICAL PRESENTATION AND INTERVENTION: A 48-year-old male, who had undergone a gastrectomy 18 months prior to admission for stage IIIA gastric adenocarcinoma, presented with a reddish induration of the cervical skin, lymphadenopathy in both supraclavicular areas and widespread subcutaneous nodules.
  • CONCLUSION: We recommend combination chemotherapy in patients with cutaneous metastasis of gastric adenocarcinoma as a safe and effective treatment.
  • [MeSH-major] Adenocarcinoma / secondary. Head and Neck Neoplasms / secondary. Skin Neoplasms / secondary. Stomach Neoplasms / pathology

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  • (PMID = 15608485.001).
  • [ISSN] 1011-7571
  • [Journal-full-title] Medical principles and practice : international journal of the Kuwait University, Health Science Centre
  • [ISO-abbreviation] Med Princ Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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50. Zheng H, Wang J, Meng Q, Liu Z, Li B, Zhu Y: [Target therapy of gefitinib in advanced adenocarcinoma of the lung]. Zhongguo Fei Ai Za Zhi; 2007 Jun 20;10(3):229-33
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  • [Title] [Target therapy of gefitinib in advanced adenocarcinoma of the lung].
  • BACKGROUND: Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor which is used to treat advanced non-small cell lung cancer, especially adenocarcinoma.
  • The aim of this study is to evaluate the efficacy, side effects and prognostic factors of gefitinib in adenocarcinoma of the lung.
  • METHODS: A total of 26 patients with advanced adenocarcinoma of the lung were enrolled in the study.
  • Age ( < 70 years old), skin rash and CEA decrease were significantly related to longer survival, however, times of prior chemotherapy and gefitinib treatment stage did not influence the survival.
  • It can significantly improve quality of life of patients with adenocarcinoma.

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  • (PMID = 21118653.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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51. Kagami S, Saeki H, Idezuki T, Yano S, Kawabata Y, Okochi H, Asahina A, Nakagawa K, Tamaki K: Epithelioid sarcoma associated with lung adenocarcinoma. J Dermatol; 2005 Nov;32(11):904-8
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  • [Title] Epithelioid sarcoma associated with lung adenocarcinoma.
  • A skin biopsy revealed polygonal, plump, or spindle-shaped epithelioid cells and lymphocytes infiltrating through the dermis.
  • A lung biopsy revealed that he had well-differentiated adenocarcinoma which expressed p53.
  • The size of the ulcer and the tumor invasion along the fasciae of muscles were decreased, however, metastasis of the epithelioid sarcoma was detected in the lymph node of the left axilla four years after the diagnosis.
  • [MeSH-major] Adenocarcinoma / diagnosis. Lung Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Sarcoma / diagnosis. Skin Neoplasms / diagnosis


52. Bassioukas K, Nakuci M, Dimou S, Kanellopoulou M, Alexis I: Zosteriform cutaneous metastases from breast adenocarcinoma. J Eur Acad Dermatol Venereol; 2005 Sep;19(5):593-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Zosteriform cutaneous metastases from breast adenocarcinoma.
  • Cutaneous metastases from breast adenocarcinoma are usually nodular, single or multiple.
  • We present a 54-year-old woman with cutaneous zosteriform nodular metastases on the right side of her thorax, and infiltration of the corresponding arm, 3 months after the excision of adenocarcinoma of her right breast.
  • [MeSH-major] Adenocarcinoma / secondary. Adenocarcinoma / surgery. Breast Neoplasms / surgery. Herpes Zoster / pathology. Skin Neoplasms / secondary

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  • (PMID = 16164715.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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53. Annam V, Panduranga C, Kodandaswamy C, Suresh DR: Primary mucinous adenocarcinoma in an ileostomy with adjacent skin invasion: a late complication of surgery for ulcerative colitis. J Gastrointest Cancer; 2008;39(1-4):138-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mucinous adenocarcinoma in an ileostomy with adjacent skin invasion: a late complication of surgery for ulcerative colitis.
  • INTRODUCTION: Adenocarcinoma of the ileostomy after colectomy performed for non-neoplastic condition are relatively uncommon.
  • Mucinous adenocarcinoma at an ileostomy site represents a late complication of total colectomy performed for ulcerative colitis.
  • CASE REPORT: We here report a case of mucinous adenocarcinoma of the mucocutaneous junction at the ileostomy site with adjacent skin invasion occurring 35 years after total colectomy for ulcerative colitis.
  • [MeSH-major] Adenocarcinoma, Mucinous / etiology. Colitis, Ulcerative / surgery. Ileal Neoplasms / etiology. Ileostomy / adverse effects. Postoperative Complications / etiology. Skin / pathology

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  • (PMID = 19418266.001).
  • [ISSN] 1941-6628
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Riley S, Wah T: Cutaneous metastasis of esophageal adenocarcinoma with an unusual presentation. J Clin Ultrasound; 2007 Jun;35(5):289-92
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  • [Title] Cutaneous metastasis of esophageal adenocarcinoma with an unusual presentation.
  • We describe an unusual presentation of a cutaneous metastasis of esophageal adenocarcinoma in the left tempero-parietal skull and the sonographic features that helped establish the diagnosis.
  • This was confirmed on CT, and a definitive diagnosis was obtained on histologic analysis following sonographically guided biopsy.
  • [MeSH-major] Adenocarcinoma / diagnosis. Esophageal Neoplasms / diagnosis. Mediastinal Neoplasms / diagnosis. Scalp. Skin Neoplasms / diagnosis. Skull Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Humans. Tomography, X-Ray Computed. Ultrasonography, Doppler, Color

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  • (PMID = 17366561.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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55. Novotny AR, Florack G, Becker K, Siewert JR: Esophageal replacement by Lexer's esophagoplasty: adenocarcinoma as late complication. Ann Thorac Surg; 2005 Sep;80(3):1122-4
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  • [Title] Esophageal replacement by Lexer's esophagoplasty: adenocarcinoma as late complication.
  • The most successful method for esophageal reconstruction in the early 20th century was the jejunodermatoesophagoplasty after Lexer, involving the presternal formation of a skin tube for passage reconstruction.
  • A 59-year-old patient presented to our hospital with adenocarcinoma at the dermatojejunostomy 47 years after undergoing a Lexer procedure.
  • Although squamous cell carcinoma is known as a late complication of dermatoesophagoplasties, this is a reported case of adenocarcinoma formation.
  • [MeSH-major] Adenocarcinoma / etiology. Esophageal Neoplasms / etiology. Esophagoplasty / adverse effects

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  • (PMID = 16122509.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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56. Ivan D, Hafeez Diwan A, Prieto VG: Expression of p63 in primary cutaneous adnexal neoplasms and adenocarcinoma metastatic to the skin. Mod Pathol; 2005 Jan;18(1):137-42
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  • [Title] Expression of p63 in primary cutaneous adnexal neoplasms and adenocarcinoma metastatic to the skin.
  • The purpose of this study was to investigate the pattern of p63 expression in cutaneous adnexal neoplasms and to assess its possible value in the differential diagnosis of primary cutaneous neoplasms vs adenocarcinomas metastatic to the skin.
  • Immunohistochemical analysis for p63 was performed on formalin-fixed, paraffin-embedded archival tissue from 20 benign adnexal tumors, 10 malignant adnexal tumors and 14 adenocarcinomas metastatic to the skin.
  • The expression of p63 was evaluated in epidermal cells, skin appendages and metastatic tumor cells. p63 was consistently expressed in the basal and suprabasal cells of epidermis and cutaneous appendages, including the basal/myoepithelial cells of sweat glands.
  • In contrast, none of the metastatic adenocarcinomas to the skin was positive for p63 (P<0.001).
  • Based on our findings, analysis of p63 expression may help in the differential diagnosis of primary vs metastatic cutaneous adenocarcinomas.
  • [MeSH-major] Adenocarcinoma / secondary. Neoplasms, Adnexal and Skin Appendage / pathology. Phosphoproteins / biosynthesis. Skin / pathology. Skin Neoplasms / pathology. Trans-Activators / biosynthesis
  • [MeSH-minor] DNA-Binding Proteins. Diagnosis, Differential. Epidermis / chemistry. Genes, Tumor Suppressor. Humans. Immunohistochemistry. Transcription Factors. Tumor Suppressor Proteins


57. Petterino C, Guazzi P, Ferro S, Castagnaro M: Bronchogenic adenocarcinoma in a cat: an unusual case of metastasis to the skin. Vet Clin Pathol; 2005 Dec;34(4):401-4
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  • [Title] Bronchogenic adenocarcinoma in a cat: an unusual case of metastasis to the skin.
  • A nodular lesion was found in the skin extending into the subcutaneous tissue of the right abdominal flank.
  • Histologic evaluation of tissues obtained at necropsy indicated a bronchogenic adenocarcinoma in the lung, with metastasis to the skin of the right flank, but no involvement of the digits.
  • Bronchogenic adenocarcinoma is an uncommon neoplasm in cats, and the digits are the most common sites of metastasis.
  • This case was unusual in that the skin of the abdominal wall was the primary site of metastasis, with no involvement of the digits.

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  • (PMID = 16270268.001).
  • [ISSN] 0275-6382
  • [Journal-full-title] Veterinary clinical pathology
  • [ISO-abbreviation] Vet Clin Pathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vimentin; 68238-35-7 / Keratins
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58. Leung TH, Lee HH, Chang SC: Perianal eccrine adenocarcinoma. World J Surg Oncol; 2007;5:100

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Perianal eccrine adenocarcinoma.
  • CONCLUSION: Even though eccrine carcinomas would appear to be rare, when dealing with recurrent skin tumors or recurrent perianal fistulas, the possibility of eccrine carcinoma should be considered by consulting clinicians.

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  • [Cites] Cancer. 1989 Jul 15;64(2):366-70 [2736482.001]
  • [Cites] J Surg Oncol. 1986 Jan;31(1):26-30 [3511326.001]
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  • (PMID = 17822569.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2034570
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59. Tan KY, Ho KS, Lai JH, Lim JF, Ooi BS, Tang CL, Eu KW: Cutaneous and subcutaneous metastases of adenocarcinoma of the colon and rectum. Ann Acad Med Singapore; 2006 Aug;35(8):585-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous and subcutaneous metastases of adenocarcinoma of the colon and rectum.
  • CLINICAL PICTURE: The first case was a 70-year-old man with T3N2M0 rectal mucinous adenocarcinoma, who developed an inflammatory subcutaneous metastasis at the left scapula 2 years after anterior resection.
  • The second case was a 51-year-old man with T4N2M0 splenic flexure mucinous adenocarcinoma, who developed metastatic disease including a subcutaneous secondary to the back.
  • The third case was a 53-year-old woman who developed vulval recurrence 10 months after abdomino-perineal resection for a low T3N1M0 rectal adenocarcinoma.
  • A high index of suspicion is recommended when encountered with unresolving skin lesions in cancer patients.
  • [MeSH-major] Adenocarcinoma / secondary. Neoplasms, Connective Tissue / secondary. Rectal Neoplasms / pathology. Skin Neoplasms / secondary. Subcutaneous Tissue
  • [MeSH-minor] Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / secondary. Aged. Female. Humans. Male. Middle Aged

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  • (PMID = 17006588.001).
  • [ISSN] 0304-4602
  • [Journal-full-title] Annals of the Academy of Medicine, Singapore
  • [ISO-abbreviation] Ann. Acad. Med. Singap.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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60. Nishimoto J, Amoh Y, Niiyama S, Takasu H, Katsuoka K: Aggressive digital papillary adenocarcinoma on the palm with pulmonary metastases. J Dermatol; 2008 Jul;35(7):468-70
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  • [Title] Aggressive digital papillary adenocarcinoma on the palm with pulmonary metastases.
  • A 41-year-old Japanese male had aggressive digital papillary adenocarcinoma with pulmonary metastases.
  • He had an asymptomatic, solitary, dome-shaped, skin-colored firm nodule on his left palm for half year.
  • Five years after the initial removal of the lesion, the patient was referred to our hospital because of a recurrent skin nodule on his left palm.
  • The recurrent skin tumor was found to have lobular proliferation of anaplastic cells.
  • On immunohistochemistry, the pulmonary metastasis and the palmar skin nodules were identical.
  • The tumor was diagnosed as an aggressive digital papillary adenocarcinoma.
  • This report is a rare case of aggressive digital papillary adenocarcinoma that was diagnosed based on the histopathology of the pulmonary metastases, which showed ductal structures associated with papillary projections.
  • [MeSH-major] Adenocarcinoma, Papillary / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology

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  • (PMID = 18705837.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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61. Xavier MH, Vergueiro Tde R, Vilar EG, Pinto JM, Issa MC, Pereira GB, Carocha AP: Cutaneous metastasis of gastric adenocarcinoma: an exuberant and unusual clinical presentation. Dermatol Online J; 2008;14(11):8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous metastasis of gastric adenocarcinoma: an exuberant and unusual clinical presentation.
  • There are different types of skin changes associated with internal malignancy.
  • One type is the skin involvement as a result of cutaneous metastasis from an internal tumor.
  • The skin is an uncommon site for distant metastasis; when it is present the most common sources are breast, lung, and colon.
  • We report an exuberant and rare case of cutaneous metastasis from gastric adenocarcinoma as the first sign of this serious visceral cancer.
  • [MeSH-major] Carcinoma, Signet Ring Cell / secondary. Skin Neoplasms / secondary. Stomach Neoplasms / diagnosis

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  • (PMID = 19094846.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 6PLQ3CP4P3 / Etoposide; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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62. Wagamon K, Ranchoff RE, Rosenberg AS, Jaworsky C: Benign lymphangiomatous papules of the skin. J Am Acad Dermatol; 2005 May;52(5):912-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign lymphangiomatous papules of the skin.
  • Benign lymphangiomatous papules of the skin are benign lymphatic proliferations that may arise in the skin after operation or radiation therapy.
  • We report a case of benign lymphangiomatous papules of the skin that occurred in a patient 4 years after undergoing radiation therapy to the chest for adenocarcinoma of the breast.
  • [MeSH-major] Breast Neoplasms / radiotherapy. Lymphangioma / pathology. Radiotherapy / adverse effects. Skin Neoplasms / pathology

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  • (PMID = 15858490.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. França AE, Salvino LK, Leite SH, Ferraz JG, Rocha TD, Cintra ML, Velho PE, Souza EM: Pyoderma gangrenosum as first clinical manifestation of gastric adenocarcinoma. J Eur Acad Dermatol Venereol; 2006 Apr;20(4):440-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pyoderma gangrenosum as first clinical manifestation of gastric adenocarcinoma.
  • Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown etiology characterized by typical skin ulcers.
  • In this setting, we describe a patient in whom PG was the first and isolated manifestation of advanced gastric adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / complications. Adenocarcinoma / diagnosis. Pyoderma Gangrenosum / complications. Pyoderma Gangrenosum / diagnosis. Stomach Neoplasms / complications. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Fatal Outcome. Gastroscopy. Humans. Male

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  • (PMID = 16643144.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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64. Limmathurotsakul D, Rerknimitr P, Korkij W, Noppakun N, Kullavanijaya P, Rerknimitr R: Metastatic mucinous cystic adenocarcinoma of the pancreas presenting as Sister Mary Joseph's nodule. JOP; 2007;8(3):344-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic mucinous cystic adenocarcinoma of the pancreas presenting as Sister Mary Joseph's nodule.
  • CONTEXT: Sister Mary Joseph's nodule usually represents metastatic cancers from gastrointestinal malignancy including adenocarcinoma of the pancreas.
  • Skin biopsy from the nodule confirmed the presence of metastatic mucinous cystadenocarcinoma.
  • [MeSH-major] Cystadenocarcinoma, Mucinous / pathology. Cystadenocarcinoma, Mucinous / secondary. Pancreatic Neoplasms / pathology. Skin Neoplasms / secondary. Umbilicus / pathology

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  • (PMID = 17495365.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / CA-19-9 Antigen; 0 / Carcinoembryonic Antigen
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65. Weiler-Bisig D, Ettlin G, Brink T, Arnold W, Glatz-Krieger K, Fischer A: Henoch-schonlein purpura associated with esophagus carcinoma and adenocarcinoma of the lung. Clin Nephrol; 2005 Apr;63(4):302-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Henoch-schonlein purpura associated with esophagus carcinoma and adenocarcinoma of the lung.
  • We report the first cases of HSP associated with carcinoma of the esophagus and adenocarcinoma of the lung, respectively.
  • [MeSH-major] Adenocarcinoma / complications. Carcinoma, Squamous Cell / complications. Esophageal Neoplasms / complications. Lung Neoplasms / complications. Purpura, Schoenlein-Henoch / etiology
  • [MeSH-minor] Biopsy. Disease Progression. Fatal Outcome. Humans. Immunoglobulin A / metabolism. Kidney / metabolism. Kidney / pathology. Male. Middle Aged. Retrospective Studies. Skin / metabolism. Skin / pathology

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  • (PMID = 15847258.001).
  • [ISSN] 0301-0430
  • [Journal-full-title] Clinical nephrology
  • [ISO-abbreviation] Clin. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Immunoglobulin A
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66. Sumrall A, Soni N: Dermatofibrosarcoma protuberans and small bowel adenocarcinoma: coincidental occurrence or genetic association? Int J Gastrointest Cancer; 2006;37(4):146-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatofibrosarcoma protuberans and small bowel adenocarcinoma: coincidental occurrence or genetic association?
  • After surgical excision and radiotherapy of dermatofibrosarcoma protuberans, the patient developed small bowel adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Dermatofibrosarcoma / pathology. Intestinal Neoplasms / pathology. Neoplasms, Second Primary / pathology. Skin Neoplasms / pathology

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  • (PMID = 18175227.001).
  • [ISSN] 1537-3649
  • [Journal-full-title] International journal of gastrointestinal cancer
  • [ISO-abbreviation] Int J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53
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67. Lifshitz OH, Berlin JM, Taylor JS, Bergfeld WF: Metastatic gastric adenocarcinoma presenting as an enlarging plaque on the scalp. Cutis; 2005 Sep;76(3):194-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic gastric adenocarcinoma presenting as an enlarging plaque on the scalp.
  • We present a case report of metastatic gastric adenocarcinoma in which the cutaneous metastases were the first sign of disease recurrence.
  • Histopathology results revealed signet-ring cells consistent with gastric adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Scalp Dermatoses / pathology. Skin Neoplasms / secondary. Stomach Neoplasms / pathology


68. Rütten A, Requena L: [Sweat gland carcinomas of the skin]. Hautarzt; 2008 Feb;59(2):151-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Sweat gland carcinomas of the skin].
  • Sweat gland carcinomas are rare malignant tumors of the skin.
  • The well-defined entities porocarcinoma, microcystic adnexal carcinoma, aggressive digital papillary adenocarcinoma, mucinous eccrine carcinoma, adenoid cystic carcinoma, spiradenocarcinoma, cylindrocarcinoma, hidradenocarcinoma are described.
  • [MeSH-major] Sweat Gland Neoplasms / diagnosis. Sweat Gland Neoplasms / therapy

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  • (PMID = 18214401.001).
  • [ISSN] 1432-1173
  • [Journal-full-title] Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
  • [ISO-abbreviation] Hautarzt
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 20
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69. Vesić S, Daković Z, Vukićević J, Vuković J, Stojković J, Medenica L: [Dermatomyositis associated with metastatic rectal adenocarcinoma: case report]. Med Pregl; 2009 Sep-Oct;62(9-10):473-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Dermatomyositis associated with metastatic rectal adenocarcinoma: case report].
  • We present a patient with paraneoplastic dermatomyositis associated with metastatic rectal adenocarcinoma.
  • CASE REPORT: A 66-year-old man was hospitalized in our Institute due to skin changes and myopathy in October 2006.
  • According to the medical documents and history, he underwent surgery because of rectal adenocarcinoma in April 2006.
  • Skin changes appeared 5 months before, while aggravation occurred 6 months after the surgery.
  • The diagnosis of dermatomyositis was based on: characteristic clinical picture; the elevated serum level of following enzymes: creatinine kinase, lactate dehydrogenase; the presence of anti-Mi 2 antibodies in serum; electromyographic finding; and by histology of the muscle biopsy.
  • Paraneoplastic nature of dermatomyositis was confirmed by computer tomography of the abdomen which revealed multiple deposits in the liver, by explorative laparotomy showing peritoneal dissemination and histopathological analysis that verified metastatic adenocarcinoma of the rectum.
  • CONCLUSION: We report a case of paraneoplastic dermatomyositis associated with metastatic rectal adenocarcinoma and lethal outcome, and suggest a comprehensive evaluation of patients with dermatomyositis older than 50 years in order to exclude or verify the occult malignancy.
  • [MeSH-major] Adenocarcinoma / secondary. Dermatomyositis / complications. Paraneoplastic Syndromes / complications. Rectal Neoplasms / complications

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  • (PMID = 20391745.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia
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70. De Broux E, Parc Y, Rondelli F, Dehni N, Tiret E, Parc R: Sutured perineal omentoplasty after abdominoperineal resection for adenocarcinoma of the lower rectum. Dis Colon Rectum; 2005 Mar;48(3):476-81; discussion 481-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sutured perineal omentoplasty after abdominoperineal resection for adenocarcinoma of the lower rectum.
  • PURPOSE: This study was designed to describe and evaluate the efficacy of sutured perineal omentoplasty on perineal wound healing after abdominoperineal resection for adenocarcinoma of the lower rectum.
  • METHODS: Charts of patients who underwent abdominoperineal resection for adenocarcinoma of the rectum from June 1995 to December 2001 were reviewed for mortality, morbidity, and perineal healing.
  • The perineal skin was then closed primarily.
  • CONCLUSIONS: This study demonstrated that sutured perineal omentoplasty is possible in the majority of patients after abdominoperineal resection for adenocarcinoma of the lower rectum with excellent primary perineal wound healing.
  • [MeSH-major] Adenocarcinoma / surgery. Omentum / surgery. Postoperative Complications. Rectal Neoplasms / surgery

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  • (PMID = 15714245.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Dai L, Fang J, Nie J, Hu W, Chen X, Han J, Tian G, Han S, Liu X: [Analysis of prognostic factors of 80 advanced NSCLC patients treated with gefitinib for more than 6 months]. Zhongguo Fei Ai Za Zhi; 2010 Nov;13(11):1050-5
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  • BACKGROUND: Some clinical predictors can be used to evaluate the efficacy of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for non-small cell lung cancer (NSCLC), including female, East-Asian, non-smoker, adenocarcinoma, skin rash, etc.
  • Compared with no skin rash and grade 0-I rash group, the patients with rash or grade ≥II rash had longer median PFS (16 months vs 13 months, P=0.171; 19 months vs 11 months, P=0.085).

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  • (PMID = 21081047.001).
  • [ISSN] 1999-6187
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Quinazolines; S65743JHBS / gefitinib
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72. Woodall CE, Li Y, Liu QH, Wo J, Martin RC: Chemoprevention of metaplasia initiation and carcinogenic progression to esophageal adenocarcinoma by resveratrol supplementation. Anticancer Drugs; 2009 Jul;20(6):437-43
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  • [Title] Chemoprevention of metaplasia initiation and carcinogenic progression to esophageal adenocarcinoma by resveratrol supplementation.
  • Resveratrol (3,5,4'-trihydroxy-trans-stilbene), a polyphenol found in the skin of the grape and red wine, has been found to have chemopreventitive effects in some carcinogenic models.
  • The effects of resveratrol on the initiation of Barrett's metaplasia and the carcinogenic progression to esophageal adenocarcinoma have not been evaluated.
  • The aim of this study was to evaluate the effects of resveratrol on the transition from reflux esophagitis to Barrett's metaplasia to dysplasia to esophageal adenocarcinoma in an established rat model.
  • In conclusion, morphological characteristics consistent with decreased esophagitis and incidences of metaplasia and esophageal adenocarcinoma were seen on histopathology in the resveratrol group.

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  • (PMID = 19398904.001).
  • [ISSN] 1473-5741
  • [Journal-full-title] Anti-cancer drugs
  • [ISO-abbreviation] Anticancer Drugs
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anticarcinogenic Agents; 0 / Stilbenes; 0 / Thiobarbituric Acid Reactive Substances; EC 1.11.1.6 / Catalase; EC 1.15.1.1 / Superoxide Dismutase; GAN16C9B8O / Glutathione; Q369O8926L / resveratrol
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73. Wang JY, Chai CY, Su YC, Soo KM, Huang YS, Huang TJ, Hsieh JS: Cutaneous metastasis from gastric adenocarcinoma: a case report. Kaohsiung J Med Sci; 2005 Jul;21(7):329-32
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  • [Title] Cutaneous metastasis from gastric adenocarcinoma: a case report.
  • Cutaneous metastasis from gastric adenocarcinoma is an infrequent disease entity.
  • Results of a skin biopsy disclosed groups of metastatic adenocarcinoma cells in the dermis and subcutaneous tissue, forming clusters and strands in a desmoplastic stroma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / secondary. Skin Neoplasms / secondary. Stomach Neoplasms / pathology

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  • (PMID = 16089312.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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74. Karasavvidou F, Potamianos SP, Barbanis S, Stathakis E, Psychos A, Kapsoritakis AN, Koukoulis G: Malakoplakia of the colon associated with colonic adenocarcinoma diagnosed in colonic biopsies. World J Gastroenterol; 2007 Dec 7;13(45):6109-11
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  • [Title] Malakoplakia of the colon associated with colonic adenocarcinoma diagnosed in colonic biopsies.
  • It has also been found in many other sites such as the gastrointestinal tract, pancreas, liver, lymph nodes, skin, respiratory tract, adrenal gland, vagina and brain.
  • Biopsies of the ascending colon mass confirmed the diagnosis of adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / complications. Colonic Neoplasms / complications. Malacoplakia / complications

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  • (PMID = 18023111.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4250902
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75. Han C, Chen YJ, Liu A, Schultheiss TE, Wong JY: Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy. Med Dosim; 2007;32(1):33-7
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  • [Title] Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy.
  • This study evaluated the efficacy of using helical tomotherapy for conformal avoidance treatment of anal adenocarcinoma.
  • In-vivo skin dose measurements were performed during conformal avoidance helical tomotherapy treatment of an anal cancer patient to verify adequate delivery of skin dose and sparing of OARs.
  • [MeSH-major] Adenocarcinoma / radiotherapy. Anus Neoplasms / radiotherapy. Radiotherapy, Intensity-Modulated / methods. Tomography, Spiral Computed / methods
  • [MeSH-minor] Female. Humans. Male. Radiotherapy Dosage. Skin / radiation effects

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  • (PMID = 17317533.001).
  • [ISSN] 0958-3947
  • [Journal-full-title] Medical dosimetry : official journal of the American Association of Medical Dosimetrists
  • [ISO-abbreviation] Med Dosim
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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76. Harrison BA, Heck SI, Hood AF: A fatal case of dermatomyositis with underlying metastatic esophageal adenocarcinoma. Cutis; 2008 Jan;81(1):26-8
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  • [Title] A fatal case of dermatomyositis with underlying metastatic esophageal adenocarcinoma.
  • We present a case of a patient who was first diagnosed with DM and, subsequently, metastatic esophageal adenocarcinoma.
  • To our knowledge, this is only the second case of metastatic esophageal adenocarcinoma associated with DM reported in the English language literature.
  • [MeSH-major] Adenocarcinoma / complications. Dermatomyositis / etiology. Esophageal Neoplasms / complications. Paraneoplastic Syndromes / pathology. Skin / pathology

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  • (PMID = 18306844.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear
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77. Basile JR, Lin YL: A salivary gland adenocarcinoma mimicking a microcystic adnexal carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Apr;109(4):e28-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A salivary gland adenocarcinoma mimicking a microcystic adnexal carcinoma.
  • We describe a salivary gland adenocarcinoma arising in the lower lip, characterized by ductal structures and cords, 3-5 cell layers in thickness, set in a dense fibrous stroma and also invading nerves, thus mimicking a MAC in both its clinical and its histopathologic appearance.
  • The diagnostic dilemma presented by this lesion is discussed, along with a differential diagnosis and brief review of the literature.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Skin Appendage / pathology. Lip Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology
  • [MeSH-minor] Biopsy. Cell Nucleus / ultrastructure. Cell Proliferation. Connective Tissue / pathology. Cytoplasm / ultrastructure. Diagnosis, Differential. Female. Fibrosis. Humans. Lip / innervation. Middle Aged. Neoplasm Invasiveness. Sclerosis

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  • [Copyright] Copyright 2010 Mosby, Inc. All rights reserved.
  • [CommentIn] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Sep;112(3):284-6 [21684772.001]
  • (PMID = 20303043.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
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78. Kanechorn Na Ayuthaya R, Patthamapasphong N, Sura T, Niumpradit N, Trachoo O: Ehlers-Danlos syndrome type IV with gastric adenocarcinoma. J Med Assoc Thai; 2008;91 Suppl 1:S166-71
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  • [Title] Ehlers-Danlos syndrome type IV with gastric adenocarcinoma.
  • The vascular type (type IV) is characterized by thin, translucent skin, easy bruising, characteristic facial appearance, and arterial, intestinal, and/or uterine fragility.
  • OBJECTIVES: To encourage a better understanding of vascular EDS as a basis for early diagnosis, prevention, and management of complications.
  • Gastric biopsy was indicative of adenocarcinoma of the stomach and gastrectomy was done.
  • [MeSH-major] Adenocarcinoma / complications. Ehlers-Danlos Syndrome / etiology. Stomach Neoplasms / complications

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  • (PMID = 18672610.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / COL3A1 protein, human; 0 / Collagen Type III
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79. Samaila MO: Adnexal skin tumors in Zaria, Nigeria. Ann Afr Med; 2008 Mar;7(1):6-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adnexal skin tumors in Zaria, Nigeria.
  • BACKGROUND: Adnexal skin tumors share many features in common and differentiate along one line.
  • METHOD: A 16-year retrospective analysis of all adnexal skin tumors seen in a large University Teaching Hospital in Nigeria from January 1991- December 2006.
  • Only two cases had a clinical diagnosis of adnexal tumor.
  • CONCLUSION: Adnexal skin tumors have distinct histological patterns which differentiates them from other cutaneous tumors.
  • [MeSH-major] Carcinoma, Skin Appendage / classification. Neoplasms, Adnexal and Skin Appendage / classification
  • [MeSH-minor] Adenocarcinoma, Sebaceous / epidemiology. Adenocarcinoma, Sebaceous / pathology. Adenoma, Sweat Gland / epidemiology. Adenoma, Sweat Gland / pathology. Adolescent. Adult. Aged. Child. Child, Preschool. Female. Hair Follicle / pathology. Head and Neck Neoplasms / epidemiology. Head and Neck Neoplasms / pathology. Humans. Infant, Newborn. Male. Middle Aged. Nigeria / epidemiology. Retrospective Studies. Sebaceous Gland Neoplasms / epidemiology. Sebaceous Gland Neoplasms / pathology. Sweat Gland Neoplasms / epidemiology. Sweat Gland Neoplasms / pathology

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  • (PMID = 18702242.001).
  • [ISSN] 1596-3519
  • [Journal-full-title] Annals of African medicine
  • [ISO-abbreviation] Ann Afr Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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80. Selim AA, Shaheen S, Lockshin N, Khachemoune A: Cutaneous metastasis of uterine adenocarcinoma: a case report and review of the literature. Cutis; 2009 Jul;84(1):33-8
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  • [Title] Cutaneous metastasis of uterine adenocarcinoma: a case report and review of the literature.
  • Cutaneous metastases from cancer are relatively uncommon in clinical practice but when present may herald the diagnosis of internal malignancy.
  • Despite the high incidence of uterine adenocarcinoma, cutaneous metastases are uncommon.
  • The diagnosis of cutaneous metastatic carcinoma hinges on histopathologic evaluation of the involved skin.
  • We discuss and review the diagnosis and management of cutaneous metastasis of uterine adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Skin Neoplasms / secondary. Uterine Neoplasms / pathology
  • [MeSH-minor] Aged. Antineoplastic Agents / therapeutic use. Diagnosis, Differential. Female. Humans

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  • (PMID = 19743722.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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81. Yilmaz Z, Bese T, Demirkiran F, Ilvan S, Sanioglu C, Arvas M, Kosebay D: Skin metastasis in ovarian carcinoma. Int J Gynecol Cancer; 2006 Jan-Feb;16 Suppl 1:414-8
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  • [Title] Skin metastasis in ovarian carcinoma.
  • We report a case of 69-year-old woman who presented with pleural metastasis of a serous papillary adenocarcinoma of the ovary.
  • After this period of time, she presented with a swollen leg, a cellulitis-like syndrome and erythematous nodules at lower abdominal wall and upper leg skin.
  • The skin biopsy revealed metastasis of adenocarcinoma in the dermis.
  • She died after 4 months of the diagnosis of the skin metastasis.
  • [MeSH-major] Adenocarcinoma, Papillary / secondary. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Ovarian Neoplasms / pathology. Pleural Neoplasms / secondary. Skin Neoplasms / secondary

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  • (PMID = 16515636.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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82. Obaidat NA, Awamleh AA, Ghazarian DM: Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region. Eur J Dermatol; 2006 Sep-Oct;16(5):576-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region.
  • We report the case of a 67-year-old woman who presented with a peri-anal skin tag.
  • To the best of our knowledge, this is the first description of a peri-anal adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Sweat Gland / pathology. Anus Neoplasms / pathology. Carcinoma in Situ / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17101482.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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83. Schwartz RA, Rothenberg J: Metastatic adenocarcinoma of breast within a benign melanocytic nevus in the context of cutaneous breast metastatic disease. J Cutan Pathol; 2010 Dec;37(12):1251-4
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  • [Title] Metastatic adenocarcinoma of breast within a benign melanocytic nevus in the context of cutaneous breast metastatic disease.
  • Metastatic breast cancer of skin may be seen in a number of forms.
  • We describe a patient with metastatic adenocarcinoma of breast within a benign melanocytic nevus and delineate this occurrence within the context of reviewing cutaneous breast metastatic disease.
  • [MeSH-major] Adenocarcinoma / pathology. Breast Neoplasms / pathology. Nevus, Pigmented / pathology. Skin Neoplasms / pathology. Skin Neoplasms / secondary

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  • [Copyright] Copyright © 2009 John Wiley & Sons A/S.
  • (PMID = 20002237.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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84. Pudroma X, Moan J, Ma LW, Iani V, Juzeniene A: A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin. Exp Dermatol; 2009 Nov;18(11):985-7
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  • [Title] A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin.
  • 5-aminolevulinic acid heptyl ester was investigated in human adenocarcinoma WiDr cells and in healthy skin of athymic nude mice in comparison with 5-aminolevulinic acid (ALA).
  • ALA heptyl ester, topically (but not systemically) applied, is a promising candidate for fluorescence diagnosis and photodynamic therapy.
  • [MeSH-major] Adenocarcinoma / drug therapy. Aminolevulinic Acid / antagonists & inhibitors. Aminolevulinic Acid / pharmacology. Photosensitizing Agents / pharmacology. Protoporphyrins / biosynthesis. Skin / drug effects. Skin Neoplasms / drug therapy

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  • (PMID = 19469901.001).
  • [ISSN] 1600-0625
  • [Journal-full-title] Experimental dermatology
  • [ISO-abbreviation] Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / 5-aminolevulinic acid heptyl ester; 0 / Photosensitizing Agents; 0 / Protoporphyrins; 553-12-8 / protoporphyrin IX; 88755TAZ87 / Aminolevulinic Acid
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85. Ioannidis O, Cheva A, Stavrakis T, Paraskevas G, Papadimitriou N, Kakoutis E, Makrantonakis A: Sister Mary Joseph's nodule as the sole presenting sign of gastric signet ring cell adenocarcinoma. Gastroenterol Clin Biol; 2010 Oct;34(10):565-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sister Mary Joseph's nodule as the sole presenting sign of gastric signet ring cell adenocarcinoma.
  • There are very few cases of gastric signet ring cell adenocarcinoma presenting as a SMJN, a fact rather striking as signet ring cell gastric carcinoma has an increased frequency of peritoneal dissemination and carcinomatosis of the peritoneum.
  • [MeSH-major] Carcinoma, Signet Ring Cell / secondary. Peritoneal Neoplasms / secondary. Sister Mary Joseph's Nodule / secondary. Skin Neoplasms / secondary. Stomach Neoplasms / pathology

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20739130.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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86. Loizzo MR, Tundis R, Menichini F, Saab AM, Statti GA, Menichini F: Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells. Cell Prolif; 2008 Dec;41(6):1002-1012
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  • [Title] Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells.
  • Antiproliferative activity was tested on amelanotic melanoma C32 cells and on renal cell adenocarcinoma cells, using the sulphorhodamine B assay.
  • RESULTS: Cupressus sempervirens ssp. pyramidalis leaf oil exerted the highest cytotoxic activity with an IC(50)value of 104.90 microg/mL against C32, followed by activity of P. orientalis and P. asperula on the renal adenocarcinoma cell line (IC(50) of 121.93 and 139.17 microg/mL, respectively). P. orientalis essential oil was also active against amelanotic melanoma with an IC(50) of 330.04 microg/mL.
  • [MeSH-major] Carcinoma, Renal Cell / drug therapy. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / drug therapy. Melanoma, Amelanotic / drug therapy. Melanoma, Amelanotic / pathology. Oils, Volatile / therapeutic use. Skin Neoplasms / drug therapy

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  • (PMID = 19040575.001).
  • [ISSN] 1365-2184
  • [Journal-full-title] Cell proliferation
  • [ISO-abbreviation] Cell Prolif.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Oils, Volatile; 0 / Plant Oils; 0 / Terpenes
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87. Kantrow SM, Ivan D, Williams MD, Prieto VG, Lazar AJ: Metastasizing adenocarcinoma and multiple neoplastic proliferations arising in a nevus sebaceus. Am J Dermatopathol; 2007 Oct;29(5):462-6
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  • [Title] Metastasizing adenocarcinoma and multiple neoplastic proliferations arising in a nevus sebaceus.
  • Nevus sebaceus of Jadassohn is a hamartoma of multiple skin structures.
  • We report a case of a 66-year-old woman with an adenocarcinoma as well as multiple neoplastic proliferations arising in a long standing nevus sebaceus on the scalp, with subsequent occipital neck metastatic disease.
  • Most of the lesion was composed of an adenocarcinoma with areas showing ductal differentiation with decapitation secretion, well-formed papillae and focal cribriform structures.
  • [MeSH-major] Adenocarcinoma / secondary. Head and Neck Neoplasms / secondary. Nevus / pathology. Skin Neoplasms / pathology


88. Morandi F, Benazzi C, Simoni P: Adenocarcinoma of apocrine sweat glands in a mouflon (Ovis musimon). J Vet Diagn Invest; 2005 Jul;17(4):389-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of apocrine sweat glands in a mouflon (Ovis musimon).
  • On the basis of histological and ultrastructural findings, this tumor was diagnosed as a tubulopapillary adenocarcinoma, arising from apocrine sweat glands of the skin.
  • [MeSH-major] Adenocarcinoma / veterinary. Apocrine Glands. Sheep Diseases / diagnosis. Sweat Gland Neoplasms / veterinary

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  • (PMID = 16131002.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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89. Berndt U, Philipsen L, Bartsch S, Hu Y, Röcken C, Bertram W, Hämmerle M, Rösch T, Sturm A: Comparative Multi-Epitope-Ligand-Cartography reveals essential immunological alterations in Barrett's metaplasia and esophageal adenocarcinoma. Mol Cancer; 2010;9:177
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparative Multi-Epitope-Ligand-Cartography reveals essential immunological alterations in Barrett's metaplasia and esophageal adenocarcinoma.
  • BACKGROUND: Barrett's esophagus (BE) is caused by gastroesophageal reflux with consecutive mucosal inflammation, predisposing patients to the development of esophageal adenocarcinoma (EAC).
  • [MeSH-major] Adenocarcinoma / immunology. Barrett Esophagus / immunology. Epitopes / analysis. Esophageal Neoplasms / immunology

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  • (PMID = 20604962.001).
  • [ISSN] 1476-4598
  • [Journal-full-title] Molecular cancer
  • [ISO-abbreviation] Mol. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Epitopes; 0 / Ligands
  • [Other-IDs] NLM/ PMC2909181
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90. Srikantia N, B R, A G R, Kalyan SN: Endometrioid endometrial adenocarcinoma in a premenopausal woman with multiple organ metastases. Indian J Med Paediatr Oncol; 2009 Apr;30(2):80-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endometrioid endometrial adenocarcinoma in a premenopausal woman with multiple organ metastases.
  • Endometrial adenocarcinoma is the third common malignancy of the female genital tract occurring most often in the postmenopausal age group.
  • We present an unusual case of endometrial adenocarcinoma in a premenopausal woman with simultaneous metastases in brain, liver, skin and skeletal system, within one month of completion of treatment.

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  • (PMID = 20596308.001).
  • [ISSN] 0975-2129
  • [Journal-full-title] Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology
  • [ISO-abbreviation] Indian J Med Paediatr Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2885881
  • [Keywords] NOTNLM ; Adjuvant chemotherapy / endometrial carcinoma / multiple organ metastases
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91. do Val IC, Almeida Filho GL, Corrêa A, Neto N: Chronic hidradenitis suppurativa and perianal mucinous adenocarcinoma. A case report. J Reprod Med; 2007 Feb;52(2):100-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chronic hidradenitis suppurativa and perianal mucinous adenocarcinoma. A case report.
  • This is the first case report of hidradenitis suppurativa in the vulvar region associated with perianal mucinous adenocarcinoma.
  • A diagnosis of perianal mucinous adenocarcinoma was made.
  • [MeSH-major] Adenocarcinoma, Mucinous / etiology. Hidradenitis Suppurativa / complications. Skin Neoplasms / etiology

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  • (PMID = 17393769.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. de la Torre E, Davel L, Jasnis MA, Gotoh T, de Lustig ES, Sales ME: Muscarinic receptors participation in angiogenic response induced by macrophages from mammary adenocarcinoma-bearing mice. Breast Cancer Res; 2005;7(3):R345-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Muscarinic receptors participation in angiogenic response induced by macrophages from mammary adenocarcinoma-bearing mice.
  • We had previously demonstrated the ability of peritoneal macrophages from LMM3 murine mammary adenocarcinoma-bearing mice (TMps) to increase the angiogenicity of LMM3 tumor cells, mainly through polyamine synthesis.
  • Angiogenesis was evaluated by counting vessels per square millimeter of skin.
  • [MeSH-major] Adenocarcinoma / physiopathology. Mammary Neoplasms, Animal / physiopathology. Neovascularization, Pathologic. Receptors, Muscarinic / physiology

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  • (PMID = 15987429.001).
  • [ISSN] 1465-542X
  • [Journal-full-title] Breast cancer research : BCR
  • [ISO-abbreviation] Breast Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Protein Isoforms; 0 / Receptors, Muscarinic; EC 1.14.99.1 / Prostaglandin-Endoperoxide Synthases; EC 3.5.3.1 / Arginase
  • [Other-IDs] NLM/ PMC1143557
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93. Kalialis LV, Breiting LB, Klausen S, Dahlstrøm K: [Primary mucinous carcinoma of the skin]. Ugeskr Laeger; 2008 Oct 20;170(43):3403-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary mucinous carcinoma of the skin].
  • Primary mucinous carcinoma of the skin is a rare malignant tumour originating from the sweat glands.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Head and Neck Neoplasms / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Lymphatic Metastasis. Middle Aged. Sweat Gland Neoplasms / pathology. Sweat Gland Neoplasms / secondary. Sweat Gland Neoplasms / surgery

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  • (PMID = 18976594.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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94. Liu CY, Liao HF, Wang TE, Lin SC, Shih SC, Chang WH, Yang YC, Lin CC, Chen YJ: Etoposide sensitizes CT26 colorectal adenocarcinoma to radiation therapy in BALB/c mice. World J Gastroenterol; 2005 Aug 21;11(31):4895-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Etoposide sensitizes CT26 colorectal adenocarcinoma to radiation therapy in BALB/c mice.
  • AIM: To investigate the combined effect of etoposide and radiation on CT26 colorectal adenocarcinoma implanted into BALB/c mice.
  • METHODS: We evaluated the radiosensitizing effect of etoposide on CT26 colorectal adenocarcinoma in a syngeneic animal model.
  • There was no skin change or hair loss in the RT and combination therapy groups.
  • CONCLUSION: Etoposide can sensitize CT26 colorectal adenocarcinoma in BALB/c mice to RT without significant toxicity.
  • [MeSH-major] Adenocarcinoma / radiotherapy. Colorectal Neoplasms / radiotherapy. Etoposide / therapeutic use. Radiotherapy / methods

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  • (PMID = 16097067.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 6PLQ3CP4P3 / Etoposide
  • [Other-IDs] NLM/ PMC4398745
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95. Hsu HC, Ho CY, Chen CH, Yang CH, Hong HS, Chuang YH: Aggressive digital papillary adenocarcinoma: a review. Clin Exp Dermatol; 2010 Mar;35(2):113-9
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for papillary adenocarcinoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive digital papillary adenocarcinoma: a review.
  • Vigorous treatment of aggressive digital papillary adenocarcinoma (ADPA), including amputation, has been recommended by most authors, but the appropriateness and effectiveness of excision as an alternative to amputation has not been systematically evaluated.
  • [MeSH-major] Adenocarcinoma, Papillary. Amputation. Skin Neoplasms


96. Gorva AD, Mohil R, Srinivasan MS: Aggressive digital papillary adenocarcinoma presenting as a paronychia of the finger. J Hand Surg Br; 2005 Oct;30(5):534

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive digital papillary adenocarcinoma presenting as a paronychia of the finger.
  • Aggressive digital papillary adenocarcinoma is a rare skin adnexal tumour, which has a predilection for the digits.
  • [MeSH-major] Adenocarcinoma, Papillary / diagnosis. Fingers / pathology. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Paronychia / diagnosis

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  • (PMID = 16055244.001).
  • [ISSN] 0266-7681
  • [Journal-full-title] Journal of hand surgery (Edinburgh, Scotland)
  • [ISO-abbreviation] J Hand Surg Br
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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97. Nisi G, Grimaldi L, Brandi C, Silvestri A, Brafa A, Calabrò M, D'Aniello C: Cutaneous metastasis of the superior lip from adenocarcinoma of the gastro-oesophageal junction. A case report. Chir Ital; 2007 Nov-Dec;59(6):883-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous metastasis of the superior lip from adenocarcinoma of the gastro-oesophageal junction. A case report.
  • The Authors report a rare case of cutaneous upper lip metastasis from an adenocarcinoma of the gastro-oesophageal junction, in a 72-year-old white man, which was excised and the defect repaired with a transposition flap from the cheek.
  • From a review of the literature, the skin is generally an uncommon site of metastasis particularly for this kind of cancer, with very few reports.
  • [MeSH-major] Adenocarcinoma / secondary. Esophageal Neoplasms. Esophagogastric Junction. Lip Neoplasms / secondary. Lip Neoplasms / surgery. Reconstructive Surgical Procedures. Skin Neoplasms / secondary. Skin Neoplasms / surgery

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  • (PMID = 18360997.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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98. Park JM, Kim DS, Oh SH, Kwon YS, Lee KH: A case of esophageal adenocarcinoma metastasized to the scalp. Ann Dermatol; 2009 May;21(2):164-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of esophageal adenocarcinoma metastasized to the scalp.
  • Lung, breast, and colorectal cancers are common primary tumors that metastasize to the skin; cutaneous metastasis usually occurs on the chest wall and abdomen as asymptomatic nodular patterns.
  • Esophageal cancer is not nearly as common as breast, lung, and colorectal cancers, and esophageal cancer rarely metastasizes to the skin.
  • Herein, we describe a case of metastatic skin cancer that originated from esophageal adenocarcinoma.

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  • (PMID = 20523777.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2861207
  • [Keywords] NOTNLM ; Adenocarcinoma / Esophagus / Metastasis / Scalp
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99. Dasanu CA, Alexandrescu DT: Bilateral Leser-Trélat sign mirroring lung adenocarcinoma with early metastases to the contralateral lung. South Med J; 2009 Feb;102(2):216-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral Leser-Trélat sign mirroring lung adenocarcinoma with early metastases to the contralateral lung.
  • We present a case featuring a unique overlap between the body areas involved by lung adenocarcinoma and the cutaneous paraneoplastic sign of Leser-Trélat.
  • In our patient, the Leser-Trélat sign consisted of explosive multiple seborrheic keratoses in combination with acanthosis nigricans, representing a remarkable geometric skin projection of lung cancer which involved both the upper lobes.
  • The recognition of this phenomenon may contribute to an early diagnosis and prompt surgical treatment of occult cancers.
  • [MeSH-major] Acanthosis Nigricans / pathology. Adenocarcinoma / pathology. Lung Neoplasms / pathology. Paraneoplastic Syndromes / pathology

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  • (PMID = 19209445.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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100. Fornaciari G: [The Aragonese mummies of the Basilica of Saint Domenico Maggiore in Naples]. Med Secoli; 2006;18(3):843-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Domenico Maggiore in Naples has allowed us to perform about 20 diagnoses, of which 5 concern infectious (smallpox, hepatitis, condyloma, syphilis and pneumonia), 3 metabolic (obesity, atherosclerosis, gallstones), I articular (DISH) and 2 neoplastic (colon adenocarcinoma and skin carcinoma) diseases.
  • Light microscopy evidenced an exophytic, papillary skin lesion, with typical connective axis and pronounced parakeratosis.
  • This study represents the first molecular diagnosis of HPV in mummies and could pave the way for further research about the secular evolution of these viruses, very important in human oncology.
  • The mummy of Ferrante I d'Aragona, King of Naples (1431-1494), revealed an adenocarcinoma extensively infiltrating the muscles of the small pelvis.

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  • (PMID = 18175625.001).
  • [ISSN] 0394-9001
  • [Journal-full-title] Medicina nei secoli
  • [ISO-abbreviation] Med Secoli
  • [Language] ita
  • [Publication-type] English Abstract; Historical Article; Journal Article
  • [Publication-country] Italy
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