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1. Haroon M, Kwong WY, Cantwell B, Walker F: A case of cetuximab-related tumour lysis syndrome in metastatic rectal carcinoma. NDT Plus; 2010 Jun;3(3):271-272

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of cetuximab-related tumour lysis syndrome in metastatic rectal carcinoma.
  • A 60-year-old man was diagnosed with a moderately differentiated adenocarcinoma in November 2006.

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  • [Cites] J Clin Oncol. 2008 May 10;26(14):2406-8 [18467734.001]
  • [Cites] Ann Oncol. 2005 May;16 Suppl 4:iv50-55 [15923430.001]
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  • [Cites] Cancer Res. 2007 Mar 15;67(6):2643-8 [17363584.001]
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  • [Cites] Eur J Cancer. 2001 Sep;37 Suppl 4:S16-22 [11597400.001]
  • (PMID = 28657052.001).
  • [ISSN] 1753-0784
  • [Journal-full-title] NDT plus
  • [ISO-abbreviation] NDT Plus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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2. Yu D, Li TG, Yao HL, Zhao H, Liu GQ, Pi ZM: [Relevant factors of lymphatic metastasis in rectal carcinoma]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2006 Feb;31(1):128-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Relevant factors of lymphatic metastasis in rectal carcinoma].
  • OBJECTIVE: To investigate the rules of lymphatic metastasis of rectal carcinoma, and to help clinical diagnosis and treatment.
  • METHODS: A retrospective analysis was performed in the 979 patients with rectal carcinoma who underwent surgical resection from 1995 to 2004.
  • RESULTS: The rate of lymph node metstasis was 71.4% for patients younger than 30 years old, 40.7% in the patients with tumor diameters over 6 centimeters, 82.5% in the patients with extraneous tumor invasion, 71.6% for patients of poor-differentiated adenocarcinoma, 70.4% for patients with mucoid adenocarcinoma, 100% for patients with signet-ring cell carcinoma and 46.4% for patients with more than half intestinal circumference invasion.
  • CONCLUSION: The lymphatic metastasis of rectal carcinoma is related to age, tumor size, intestinal circumference invasion, depth of tumor invasion and the differentiating degree of the tumor; the differentiating degree is the major factor.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Signet Ring Cell / pathology. Lymphatic Metastasis. Rectal Neoplasms / pathology
  • [MeSH-minor] Adult. Age Factors. Female. Humans. Logistic Models. Male. Middle Aged. Neoplasm Invasiveness. Retrospective Studies

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  • (PMID = 16562693.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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3. Murhekar KM, Majhi U, Mahajan V, Satheesan B: Penile metastasis from rectal carcinoma. Indian J Cancer; 2007 Oct-Dec;44(4):155-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Penile metastasis from rectal carcinoma.
  • In the present communication, we report an unusual case of penile metastasis from rectal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Penile Neoplasms / secondary. Rectal Neoplasms / pathology

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  • (PMID = 18322358.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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4. Matthaei H, Bölke E, Schmelzle M, Budach W, Orth K, Engers R, Cohnen M, Matuschek C, Gripp S, Knoefel WT, Peiper M: Modern therapy of rectal carcinoma. Eur J Med Res; 2008 Apr 30;13(4):139-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Modern therapy of rectal carcinoma.
  • Throughout the past decade the treatment of rectal carcinoma has improved remarkably.
  • However, surgery revolutionized by TME (total mesorectal excision) remains the only curative treatment for rectal carcinoma.
  • In this study the authors review the developments as well as the current status of modern treatment for rectal carcinoma.
  • [MeSH-major] Neoplasm Recurrence, Local / prevention & control. Rectal Neoplasms / surgery. Rectal Neoplasms / therapy

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  • (PMID = 18504168.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 46
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5. Yano H, Ohnishi T, Kanoh T, Monden T: Hand-assisted laparoscopic low anterior resection for rectal carcinoma. J Laparoendosc Adv Surg Tech A; 2005 Dec;15(6):611-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hand-assisted laparoscopic low anterior resection for rectal carcinoma.
  • Laparoscopic low anterior resection for rectal carcinoma has never been widely accepted among general surgeons because of the technical difficulties encountered during pelvic dissection.
  • We describe our technique of hand-assisted laparoscopic low anterior resection (HAL-LAR) for rectal carcinoma using the Lapdisc abdominal wall sealing device (Hakko Medical, Tokyo, Japan, and Ethicon Endo- Surgery, New Brunswick, New Jersey) which results in pelvic dissection almost equivalent to the laparotomic operation.
  • Thirteen patients with rectal adenocarcinoma (lower edge less than 15 cm from the anal verge) underwent laparoscopic low anterior resection, including 8 standard laparoscopic low anterior resections (SL-LAR) and 5 HAL-LAR.
  • One patient in the SL-LAR group was found to have anastomotic recurrence in the staple suture line 10 months after surgery and died from cancer 24 months after surgery.
  • [MeSH-major] Adenocarcinoma / surgery. Laparoscopy / methods. Rectal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Blood Loss, Surgical. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Postoperative Complications. Treatment Outcome

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  • (PMID = 16366868.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Bretagnol F, Lelong B, Laurent C, Moutardier V, Rullier A, Monges G, Delpero JR, Rullier E: The oncological safety of laparoscopic total mesorectal excision with sphincter preservation for rectal carcinoma. Surg Endosc; 2005 Jul;19(7):892-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The oncological safety of laparoscopic total mesorectal excision with sphincter preservation for rectal carcinoma.
  • BACKGROUND: Although experience of laparoscopic treatment of rectal carcinoma has been reported, there is no evidence of its oncological safety because most procedures included partial mesorectal excision or abdominoperineal excision and quality of surgery is lacking.
  • The aim of this study was to assess the oncological results of laparoscopic total mesorectal excision with sphincter preservation for rectal carcinoma.
  • METHODS: From 2000 to 2003, 144 patients underwent laparoscopic total mesorectal excision with low colorectal or coloanal anastomosis for mid and low rectal adenocarcinoma.
  • CONCLUSIONS: A high quality of surgical excision can be achieved by the laparoscopic dissection, suggesting that this approach in treatment of rectal carcinoma is oncologically safe.
  • [MeSH-major] Adenocarcinoma / surgery. Laparoscopy. Rectal Neoplasms / surgery

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  • (PMID = 15920688.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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7. Ju H, Xu D, Li D, Chen G, Shao G: Comparison between endoluminal ultrasonography and spiral computerized tomography for the preoperative local staging of rectal carcinoma. Biosci Trends; 2009 Apr;3(2):73-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison between endoluminal ultrasonography and spiral computerized tomography for the preoperative local staging of rectal carcinoma.
  • The aim of this study is to compare the efficacy of endoluminal ultrasonography (EUS) and spiral computerized tomography (SCT) in preoperative local staging of rectal carcinoma.
  • EUS and SCT were performed prior to surgery in 78 patients with rectal carcinoma.
  • [MeSH-major] Endosonography / methods. Neoplasm Staging / methods. Rectal Neoplasms / ultrasonography. Tomography, Spiral Computed / methods

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  • (PMID = 20103950.001).
  • [ISSN] 1881-7823
  • [Journal-full-title] Bioscience trends
  • [ISO-abbreviation] Biosci Trends
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
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8. Wu ZY, Wan J, Zhao G, Peng L, Du JL, Yao Y, Liu QF, Lin HH: Risk factors for local recurrence of middle and lower rectal carcinoma after curative resection. World J Gastroenterol; 2008 Aug 14;14(30):4805-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Risk factors for local recurrence of middle and lower rectal carcinoma after curative resection.
  • AIM: To explore the risk factors for local recurrence of middle and lower rectal carcinoma after curative resection.
  • METHODS: Specimens of middle and lower rectal carcinoma from 56 patients who received curative resection at the Department of General Surgery of Guangdong Provincial People's Hospital were studied.
  • The relations between clinicopathologic characteristics, mesorectal metastasis and circumferential resection margin status were identified in patients with local recurrence of middle and lower rectal carcinoma.
  • RESULTS: Local recurrence of middle and lower rectal carcinoma after curative resection occurred in 7 of the 56 patients (12.5%), and was significantly associated with family history (c2=3.929, P=0.047), high CEA level (c2=4.964, P=0.026), cancerous perforation (c2=8.503, P=0.004), tumor differentiation (c2=9.315, P=0.009) and vessel cancerous emboli (c2=11.879, P=0.001).
  • In contrast, no significant correlation was found between local recurrence of rectal carcinoma and other variables such as age (c2=0.506, P=0.477), gender (c2=0.102, c2=0.749), tumor diameter (c2=0.421, P=0.516), tumor infiltration (c2=5.052, P=0.168), depth of tumor invasion (c2=4.588, P=0.101), lymph node metastases (c2=3.688, P=0.055) and TNM staging system (c2=3.765, P=0.152).
  • The local recurrence rate of middle and lower rectal carcinoma was 33.3% (4/12) in patients with positive circumferential resection margin and 6.8% (3/44) in those with negative circumferential resection margin.
  • Local recurrence of rectal carcinoma occurred in 6 of 36 patients (16.7%) with mesorectal metastasis, and in 1 of 20 patients (5.0%) without mesorectal metastasis.
  • CONCLUSION: Family history, high CEA level, cancerous perforation, tumor differentiation, vessel cancerous emboli and circumferential resection margin status are the significant risk factors for local recurrence of middle and lower rectal carcinoma after curative resection.
  • [MeSH-major] Carcinoma / surgery. Digestive System Surgical Procedures. Neoplasm Recurrence, Local. Rectal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoembryonic Antigen / analysis. Cell Differentiation. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Pedigree. Risk Factors. Treatment Outcome

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  • (PMID = 18720544.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen
  • [Other-IDs] NLM/ PMC2739345
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9. Sengul N, Wexner SD, Woodhouse S, Arrigain S, Xu M, Larach JA, Ahn BK, Weiss EG, Nogueras JJ, Berho M: Effects of radiotherapy on different histopathological types of rectal carcinoma. Colorectal Dis; 2006 May;8(4):283-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effects of radiotherapy on different histopathological types of rectal carcinoma.
  • BACKGROUND: Down staging by pre-operative chemoradiotherapy is currently considered part of the standard therapeutic approach to rectal carcinoma.
  • The aim of this study was to assess the response to chemoradiotherapy of different histopathological types of rectal carcinoma with emphasis on the mucinous variant.
  • METHOD: Between 1997 and 2002, 71 patients who received pre-operative chemoradiotherapy followed by surgery for rectal carcinoma were enrolled in the study.
  • Staging of the rectal carcinoma was performed according to transrectal ultrasound findings (TN score) prior to the chemoradiotherapy.
  • CONCLUSION: Mucinous carcinoma was associated with a lower response to pre-operative chemo-radiotherapy in this group of rectal carcinoma patients.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / therapy. Neoadjuvant Therapy. Radiotherapy, Adjuvant. Rectal Neoplasms / pathology. Rectal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antimetabolites, Antineoplastic / administration & dosage. Female. Fluorouracil / administration & dosage. Humans. Male. Middle Aged. Neoplasm Staging. Remission Induction. Retrospective Studies. Treatment Outcome

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  • (PMID = 16630231.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; U3P01618RT / Fluorouracil
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10. Merkel S, Klossek D, Göhl J, Papadopoulos T, Hohenberger W, Hermanek P: Quality management in rectal carcinoma: what is feasible? Int J Colorectal Dis; 2009 Aug;24(8):931-42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quality management in rectal carcinoma: what is feasible?
  • PURPOSE: A cohort study was carried out to analyse quality indicators in the diagnosis and treatment of rectal carcinoma.
  • METHODS: A total of 2,470 patients with rectal carcinoma treated between 1985 and 2007 at the Department of Surgery, University of Erlangen, were analysed and compared within four time intervals.
  • The progress in diagnosis and treatment requires a continuous update of definitions and target values.
  • [MeSH-major] Carcinoma / diagnosis. Carcinoma / therapy. Digestive System Surgical Procedures / standards. Outcome and Process Assessment (Health Care) / standards. Quality Indicators, Health Care / standards. Rectal Neoplasms / diagnosis. Rectal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant / standards. Feasibility Studies. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoadjuvant Therapy / standards. Neoplasm Recurrence, Local. Prospective Studies. Radiotherapy, Adjuvant / standards. Registries. Risk Assessment. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 19488770.001).
  • [ISSN] 1432-1262
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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11. Safioleas M, Stamatakos M, Iannescu R, Safioleas C, Kostakis A: The coexistence of carcinoma of the rectum and of ischiorectal abscess: what is the optimal therapeutic approach? Chirurgia (Bucur); 2007 Mar-Apr;102(2):221-2
MedlinePlus Health Information. consumer health - Rectal Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The coexistence of carcinoma of the rectum and of ischiorectal abscess: what is the optimal therapeutic approach?
  • This article deals with the dilemma of the surgeon to choose the optimal surgical procedure in case of coexistence of ischiorectal abscess and a rectal carcinoma.
  • The case of a patient suffering from ischiorectal abscess in association with rectal carcinoma is reported.
  • [MeSH-major] Abscess / surgery. Carcinoma / surgery. Ischium. Rectal Diseases / surgery. Rectal Fistula / surgery. Rectal Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Abscess.
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  • (PMID = 17615926.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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12. Li SY, Yu B, Liang ZJ, Yuan SJ, Chen G, Chen G, Bai X: [Analysis of 618 cases of radical resection of rectal carcinoma]. Zhonghua Wai Ke Za Zhi; 2005 Oct 1;43(19):1259-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of 618 cases of radical resection of rectal carcinoma].
  • OBJECTIVE: To investigate and analyse curative effects of Miles operation and anal sphincter preserving operation for rectal carcinoma in 20 years.
  • METHODS: From 1984 to 2004, 618 cases of rectal carcinoma that underwent radical resection including Miles operation and anal sphincter preserving procedures were analysed retrospectively each 10 years, earlier 10 years from 1984 to 1994, and later 10 years from 1994 to 2004.
  • With the procedure of canular anastomosis of colon and rectal mucosa, the local recurrence rate was 4.9%.
  • With the procedure of canular anastomosis of colon and rectal mucosa, the five-year survival rate was 71.3% (62/87).
  • CONCLUSIONS: The operation for rectal cancer should be chosen individually according to locus, biological character, and clinical stages.
  • [MeSH-major] Proctocolectomy, Restorative / methods. Rectal Neoplasms / surgery

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  • (PMID = 16271224.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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13. Katsumoto Y, Aritake N, Yamamoto H: [Multimodal therapy for juvenile advanced rectal carcinoma]. Gan To Kagaku Ryoho; 2008 Nov;35(12):2135-7
MedlinePlus Health Information. consumer health - Cancer Chemotherapy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Multimodal therapy for juvenile advanced rectal carcinoma].
  • A 37-year-old male with locally advanced rectal carcinoma and liver metastasis was treated by multimodal therapy.
  • The rectal tumor showed a reduction in size, total pelvic evisceration combined with reconstruction of ileal conduit and rectus abdominus myocutaneous (RAM) flap were performed.
  • Recent studies for outcomes in young colorectal carcinoma patients showed that the poor prognosis was not caused by its proper aggressiveness in biologic behavior but just the late diagnosis.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Rectal Neoplasms / drug therapy. Rectal Neoplasms / radiotherapy
  • [MeSH-minor] Adult. Bone Neoplasms / drug therapy. Bone Neoplasms / secondary. Bone Neoplasms / surgery. Combined Modality Therapy. Humans. Liver Neoplasms / drug therapy. Liver Neoplasms / radiography. Liver Neoplasms / secondary. Liver Neoplasms / surgery. Male. Neoplasm Staging. Surveys and Questionnaires. Tomography, X-Ray Computed

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  • (PMID = 19106548.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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14. Larbaoui B: Preoperative concomitant chemoradiotherapy with capecitabine in locally advanced rectal carcinoma. J Clin Oncol; 2009 May 20;27(15_suppl):e15134

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative concomitant chemoradiotherapy with capecitabine in locally advanced rectal carcinoma.
  • : e15134 Background: Preoperative concomitant chemoradiotherapy has shown to improve local control and sphincter preservation with decreased acute toxicity compared with postoperative treatment in locally advanced rectal carcinoma.
  • METHODS: Inclusion criteria: rectal adenocarcinoma <12 cms from anal verge, clinical stage T3-4, adequate renal, hematological and liver function.
  • CONCLUSIONS: Preliminary results show that preoperative concomitant chemoradiotherapy with Capecitabine is an effective regimen with an acceptable safety profile for locally advanced rectal cancer, leading to a high probability of tumor downstaging.

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  • (PMID = 27960909.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Matuschek C, Bölke E, Gripp S, Budach W, Hermsen D, Peiper M: Mediator release during combined radio chemotherapy in rectal carcinoma. J Clin Oncol; 2009 May 20;27(15_suppl):3043

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mediator release during combined radio chemotherapy in rectal carcinoma.
  • Today neoadjuvant chemoradiotherapy is the gold standard for uT3, N+ rectal cancer.
  • The aim of this study was to evaluate if a gut barrier dysfunction occurred during radiotherapy and elective rectal surgery.
  • METHODS: We investigated in 45 patients (25 male, 20 female) with uT3N+ rectal carcinoma and neoadjuvante long-term radio chemotherapy with 5-FU and pelvis irridation up to 50.4 Gy on admission and weekly during radiotherapy and after surgery IL-6, LPS-binding protein, IL-8, TNF-α and procalcitonin.

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  • (PMID = 27961978.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Comella P, Massidda B, Natale D, Filippelli G, Farris A, Condemi G, Palmeri S, Tafuto S, Vessia G, Barberis G: Bevacizumab (Bev), irinotecan (IRI), folinic acid (FA), and 5-fluorouracil (FU) every 2 weeks (BIFF regimen) as first-line treatment for metastatic colorectal cancer (MCRC) patients (pts): The SICOG experience. J Clin Oncol; 2009 May 20;27(15_suppl):e15067

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bevacizumab (Bev), irinotecan (IRI), folinic acid (FA), and 5-fluorouracil (FU) every 2 weeks (BIFF regimen) as first-line treatment for metastatic colorectal cancer (MCRC) patients (pts): The SICOG experience.
  • Fifty-six pts had a colon, and 29 pts a rectal carcinoma.
  • Twenty-one (25%) pts had an unresected primary (colon 13, rectum 8).

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  • (PMID = 27964522.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Wortham AH, Schreiber D, Rineer J, Katsoulakis E, Sroufe R, Marienberg E, Nwokedi E, Han P, Choi K, Rotman M: Overall survival using local excision techniques with and without radiation compared with APR for stage I rectal cancer: A SEER based analysis. J Clin Oncol; 2009 May 20;27(15_suppl):4032

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Overall survival using local excision techniques with and without radiation compared with APR for stage I rectal cancer: A SEER based analysis.
  • : 4032 Background: The standard of care for Stage I rectal cancer is radical resection.
  • This analysis compares the outcomes of sphincter sparing treatment with radical surgery in Stage I rectal cancer.
  • METHODS: Using the Surveillance, Epidemiology and End-Results (SEER) registry, we performed a query of patients with Stage T1-2N0 (T=4 cm or less) rectal adenocarcinoma between 1988 and 2003 who were treated with either local excision alone (LE), local excision followed by radiotherapy (LE+RT) or abdominoperineal resection (APR).
  • CONCLUSIONS: According to this analysis, there was no statistical difference in survival for patients with Stage I rectal carcinoma undergoing APR versus LE+RT.

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  • (PMID = 27961548.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Moreno Garcia V, Cejas P, Feliu J, De Castro J, Belda-Iniesta C, Barriuso J, Larrauri J, Gonzalez Baron M, Casado E: Immunohistochemical analysis of tumor regression grade for rectal cancer after neoadjuvant chemoradiotherapy. J Clin Oncol; 2009 May 20;27(15_suppl):e22089

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical analysis of tumor regression grade for rectal cancer after neoadjuvant chemoradiotherapy.
  • : e22089 Background: Tumor regression grade (TRG) as defined by Rodel et al. has been suggested as an independent prognostic factor for rectal carcinoma patients treated by preoperative chemoradiotherapy (CRT).
  • CONCLUSIONS: The EGFR/CD133 double negative rectal tumors with TRG 2 or 3 after chemoradiotherapy show a higher risk of relapse or death.

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  • (PMID = 27963266.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. McLeod HL, Myerson RJ, Zehnbauer B, Trinkaus K, Malyapa RS, Mutch MG, Abbey EE, Alyasiry A, Fleshman JW, Tan BR: TYMS genotype-directed neoadjuvant chemoradiation for rectal cancer. J Clin Oncol; 2009 May 20;27(15_suppl):4028

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] TYMS genotype-directed neoadjuvant chemoradiation for rectal cancer.
  • : 4028 Background: Downstaging (DS) of rectal cancers is achieved in 45% of pts with neoadjuvant 5FU and radiation (XRT).
  • We conducted a prospective single-institution Phase II study using TYMS genotyping to direct neoadjuvant chemoRT for pts with rectal cancer.
  • METHODS: Pts with T3/ T4, N0-2, M0-1 rectal adenocarcinoma staged with transrectal ultrasound (TRUS) or CT/MRI are eligible.
  • CONCLUSIONS: This is the first study to prospectively use TYMS genotyping to direct neoadjuvant chemoXRT in pts with rectal cancer.
  • These results are encouraging for the conduct of a randomized study of genotype-guided neoadjuvant therapy for locally advanced rectal cancer.

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  • (PMID = 27961521.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Nogue M, Salud A, Vicente P, Pericay C, Arriví A, Roca JM, Losa F, Ponce J, Safont MJ, Guasch I: Addition of bevacizumab to induction plus concomitant capecitabine-oxaliplatin (XELOX) chemoradiotherapy (CRT) in MRI poor prognosis locally advanced rectal cancer: Avacross study. J Clin Oncol; 2009 May 20;27(15_suppl):4100

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Addition of bevacizumab to induction plus concomitant capecitabine-oxaliplatin (XELOX) chemoradiotherapy (CRT) in MRI poor prognosis locally advanced rectal cancer: Avacross study.
  • : 4100 Background: Concomitant CRT with 5-FU followed 6-8 weeks later by TME surgery is well accepted standard treatment for locally advancer rectal cancer.
  • METHODS: Eligible patients (pts) had high-risk rectal adenocarcinoma defined by MRI: distal T3 at/below levators, T3 at any other level within 2 mm of mesorectal fascia, resectable T4 and any T3 with nodal metastases.

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  • (PMID = 27961205.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Gamelin E, Mineur L, Chevelle C, Cailleux P, Martin L, Bastit L, Roullet B, Hasbini A, Savary J, Cellier P: Neoadjuvant radiotherapy ± tegafur-uracil plus leucovorin in rectal adenocarcinoma: Final results of a French multicenter phase III study. J Clin Oncol; 2009 May 20;27(15_suppl):4104

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neoadjuvant radiotherapy ± tegafur-uracil plus leucovorin in rectal adenocarcinoma: Final results of a French multicenter phase III study.
  • : 4104 Background: Neoadjuvant chemoradiotherapy (CRT) with tegafur-uracil (UFT) plus leucovorin (LV) has shown promising results in patients with rectal adenocarcinoma (RAC).

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  • (PMID = 27961187.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Djellali L, Larbaoui B, Boukerche A, Ghazi S, Chaiba I, Meziane N, Yekrou D, Youcef DF: Preoperative concomitant chemoradiotherapy with oxaliplatin and 5-fluorouracil in locally advanced rectal carcinoma. J Clin Oncol; 2009 May 20;27(15_suppl):e15108

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative concomitant chemoradiotherapy with oxaliplatin and 5-fluorouracil in locally advanced rectal carcinoma.
  • : e15108 Background: Preoperative concomitant chemoradiotherapy has shown to improve local control and sphincter preservation with decreased acute toxicity compared with postoperative treatment in locally advanced rectal carcinoma.
  • Secondary endpoint was sphincter preservation and toxicity Methods: Inclusion criteria: rectal adenocarcinoma <12 cms from anal verge, clinical stage T3-4, adequate renal, hematological and liver function.
  • Main adverse effects (NCI-CTC): diarrhea G3-4: 14.2%, sensitive peripheral neurotoxicity G1: 26.6%, nausea/vomiting G3-4: 11%, Anemia G3-4: 7.1%, neutropenia G3-4: 14.2% Conclusions: Preliminary results show that preoperative concomitant chemoradiotherapy with oxaliplatin and 5FU-folinic acid is an effective regimen with an acceptable safety profile for locally advanced rectal cancer, leading to a high probability of tumor downstaging.

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  • (PMID = 27964340.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Gasent Blesa J, Alberola Candel V, Juan O, Provencio Pulla M, Giner Marco V, Gravalos C, Fernandez I, Llorca C: Neoadjuvant chemoradiotherapy in rectal cancer patients (pt) with oxaliplatin (Ox) and capecitabine (Cp): Results of a phase II trial. J Clin Oncol; 2009 May 20;27(15_suppl):e15101

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neoadjuvant chemoradiotherapy in rectal cancer patients (pt) with oxaliplatin (Ox) and capecitabine (Cp): Results of a phase II trial.
  • : e15101 Background: Between April 2006 and May 2008, 27 rectal adenocarcinoma pt were included (cT3: 25 pt, T4: 2 pt, N0: 11 Pt, N+: 16 pt), stages II-III, RMN staged, 14 male and 13 female.

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  • (PMID = 27964345.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Pinto C, Di Fabio F, Maiello E, Di Tullio P, Pini S, Aschele C, Garufi C, Bochicchio A, Pinotti G, Latiano T, Martoni A: Phase II study of preoperative panitumumab, 5-fluorouracil, and oxaliplatin with concurrent radiotherapy in locally advanced rectal cancer: Preliminary safety results (StarPan /STAR-02 Study). J Clin Oncol; 2009 May 20;27(15_suppl):4110

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase II study of preoperative panitumumab, 5-fluorouracil, and oxaliplatin with concurrent radiotherapy in locally advanced rectal cancer: Preliminary safety results (StarPan /STAR-02 Study).
  • : 4110 Background: The aim of this phase II study is to assess the activity of preoperative external radiotherapy combined with panitumumab, oxaliplatin and 5-fluorouracil in locally advanced rectal cancer patients (pts).
  • METHODS: Pts entering the study had histologically-proven rectal adenocarcinoma, either uT3N+ or T4 N-/+ stage, with location <12 cm from the anal margin.
  • Rectal surgery was performed 7-8 weeks after the end of neoadjuvant treatment.

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  • (PMID = 27961230.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Carlsson G, Bjökqvist H, Kurlberg G, Torbjörn S, Casillas M, Holmqvist M, Stoffregen C, Gustavsson B: Feasibility of treatment of resectable rectal cancer with neoadjuvant treatment with pemetrexed. J Clin Oncol; 2009 May 20;27(15_suppl):e15121

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Feasibility of treatment of resectable rectal cancer with neoadjuvant treatment with pemetrexed.
  • : e15121 Background: Multimodality strategies of chemo- and radiotherapy (RT) in the neoadjuvant setting of resectable rectal cancer are a challenge to optimize surgery outcome.
  • Pemetrexed (P) has shown efficacy in colorectal cancer.
  • This phase II trial evaluated its feasibility as neo-adjuvant monotherapy for patients (pts) with resectable rectal cancer.
  • METHODS: Between June' 06 and January' 08, 37 pts with a histologically proven diagnosis of operable rectal adenocarcinoma were enrolled.
  • 12 out of 13 planned pts had a rectum amputation.

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  • (PMID = 27960841.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Vávra P, Rydlová M, Pelikán A, Gunková P, Matínek L, Gunka I, Vávrová M, Andĕl P: [Safe distance of the inferior resection line in the rectal carcinoma surgery]. Rozhl Chir; 2006 Jan;85(1):45-50

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Safe distance of the inferior resection line in the rectal carcinoma surgery].
  • [Transliterated title] Bezpecná vzdálenost dolní resekcní linie pri operaci karcinomu rekta.
  • The authors present results of a study of a distal intramural spread of the rectal carcinoma beneath its aboral margin, which was conducted over several years.
  • The authors also confirmed that the distal intramural spread of the tumor is fairly rare and, at the same time, it signifies a highly advanced and aggressive disorder with a poor prognosis.
  • Furthermore, the authors have not recorded cases of the differenciated adenocarcinoma spread, even at the distance of 2 mm from the aboral margin of the tumor.
  • [MeSH-major] Carcinoma / surgery. Rectal Neoplasms / surgery. Rectum / surgery

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  • (PMID = 16541642.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
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27. Gunková P, Dostalík J, Martínek L, Gunka I, Pelikán A, Andel P, Rydlová M, Vávrová M: [The rectal carcinoma treatment history]. Rozhl Chir; 2006 Feb;85(2):74-7; discussion 77

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The rectal carcinoma treatment history].
  • [Transliterated title] Historie lécby karcinomu rekta.
  • The authors demonstrate a history of the rectal carcinoma surgical therapy, based on the available literature data or on oral information.
  • Furthermore, they add their own experience with treatment of the rectal carcinoma, the disorder, which in the Czech Republic and, namely, in the Northern Moravian region, has one of the highest worldwide incidence rates.
  • [MeSH-major] Colorectal Surgery / history. Rectal Neoplasms / history

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  • (PMID = 16626015.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] English Abstract; Historical Article; Journal Article
  • [Publication-country] Czech Republic
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28. Xu FY, Di MJ, Dong JK, Wang FJ, Jin YS, Zhu YM, Lai MD: [Influence of clinical and pathomorphological parameters on prognosis in colon carcinoma and rectal carcinoma]. Zhejiang Da Xue Xue Bao Yi Xue Ban; 2006 May;35(3):303-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Influence of clinical and pathomorphological parameters on prognosis in colon carcinoma and rectal carcinoma].
  • OBJECTIVE: To investigate the effects of clinical and pathomorphological parameters on the prognosis of colon carcinoma and rectal carcinoma.
  • METHODS: Univariate and multivariate COX proportional hazard models were used to study the effects of the clinical and pathomorphological factors on the prognosis in 101 cases of colon carcinoma, 219 of rectal carcinoma and 137 of rectal carcinoma under curative resections.
  • RESULT: By using univariate analysis, we identified that lymph node metastasis and distant metastasis were the common prognostic factors for both colon carcinoma and rectal carcinoma.
  • Smoking, deep infiltration, chemotherapy and serum albumin concentration were the uncertain prognostic factors for colon carcinoma.
  • Signet-ring cell carcinoma, larger tumor size (>6 cm), deep infiltration, lack of radical surgery, and advanced TNM stage were the exclusive adverse prognostic factors for rectal carcinoma.
  • Further studies showed that the adverse prognostic factors for the rectal carcinoma under curative resection included deep infiltration, lymph node metastasis, vessel invasion, less of peritumoral lymphocyte infiltration, lack of Crohn's like reactivity, high level of tumor budding, advanced TNM stage and positive urine glucose.
  • By using multivariate analysis based on a COX proportional hazard model, it was identified that smoking, lymph node metastasis and serum albumin concentration were independent prognostic factors for colon carcinoma; advanced TNM stage, distant metastasis and palliative surgery for rectal carcinoma; and vessel invasion, lymph node metastasis and urine glucose for rectal carcinoma under curative resections.
  • CONCLUSION: The various clinical and pathomorphological parameters show different prognostic value for colon carcinoma, rectal carcinoma and rectal carcinoma under curative resections.
  • [MeSH-major] Colonic Neoplasms / pathology. Rectal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Carcinoma, Signet Ring Cell / pathology. Carcinoma, Signet Ring Cell / surgery. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Prognosis. Proportional Hazards Models

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  • (PMID = 16764034.001).
  • [ISSN] 1008-9292
  • [Journal-full-title] Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
  • [ISO-abbreviation] Zhejiang Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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29. Ramanathan Y, Rajagopalan R, Rahman NA: Laryngeal metastasis from a rectal carcinoma. Ear Nose Throat J; 2007 Nov;86(11):685-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal metastasis from a rectal carcinoma.
  • We report a case of a laryngeal metastasis from a rectal carcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Laryngeal Neoplasms / secondary. Rectal Neoplasms / pathology

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  • (PMID = 18225631.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Hempen HG, Raab HR: [Therapy of locally recurrent rectal carcinoma]. Chirurg; 2009 Apr;80(4):311-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Therapy of locally recurrent rectal carcinoma].
  • During the last decade no gastrointestinal tumor underwent such profound modifications in diagnostics and therapy as rectal cancer (total mesorectal excision, multimodal therapy).
  • Despite all efforts and continuous improvements in the results of oncological treatment, local recurrence of rectal carcinoma is still a considerable problem.
  • Surgical oncology today has the ability for remarkable improvement in the prognosis of locally recurrent rectal cancer.
  • [MeSH-major] Neoplasm Recurrence, Local / surgery. Rectal Neoplasms / surgery
  • [MeSH-minor] Combined Modality Therapy. Diagnostic Imaging. Disease-Free Survival. Humans. Neoplasm Invasiveness. Neoplasm Staging. Palliative Care. Prognosis. Reoperation. Sensitivity and Specificity

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  • (PMID = 19350308.001).
  • [ISSN] 1433-0385
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 32
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31. Matsuhisa T, Taguchi K, Fukumori D, Imai A, Minato M: [Preoperative chemoradiotherapy for advanced lower rectal carcinoma]. Gan To Kagaku Ryoho; 2008 Aug;35(8):1325-9
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  • [Title] [Preoperative chemoradiotherapy for advanced lower rectal carcinoma].
  • Preoperative chemoradiotherapy in combination with radiation of 30 Gy and chemotherapy with oral uracil-tegafur for 14 patients with advanced lower rectal carcinoma was performed.
  • Preoperative lymphnodes were diagnosed as cN0 in 8 cases, cN1(metastases of perirectal nodes)in 4, cN1(perirectal and along superior rectal artery nodes)in 1, and cN3(perirectal and lateral nodes)in 1.
  • Efficacy for primary carcinomas was evaluated as Partial Response in 9 cases, Stable Disease in 5 and perirectal nodes were down-sized in 4 without down-sizing of either along superior rectal artery nodes or lateral nodes.
  • Autonomic nerve-preserving resections with lymphadenectomy of perirectal and along superior rectal artery nodes were performed.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Rectal Neoplasms / drug therapy. Rectal Neoplasms / radiotherapy
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Female. Humans. Lymphatic Metastasis / pathology. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 18701843.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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32. Rouanet P: [Preoperative treatment impact for ultralow rectal carcinoma sphincter preservation]. Cancer Radiother; 2006 Nov;10(6-7):451-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Preoperative treatment impact for ultralow rectal carcinoma sphincter preservation].
  • [Transliterated title] Impact des traitements préopératoires (radiothérapie et chimiothérapie) dans la conservation sphinctérienne des cancers du très bas rectum.
  • Sphincter preservation for low rectal carcinoma must be evaluated with a plurifactoriel approach.
  • [MeSH-major] Limb Salvage. Reconstructive Surgical Procedures / methods. Rectum

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  • (PMID = 17005428.001).
  • [ISSN] 1278-3218
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 23
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33. Kilickap S, Aksoy S, Dinçer M, Saglam EA, Yalçin S: Cutaneous metastases of signet cell carcinoma of the rectum without accompanying visceral involvement. South Med J; 2006 Oct;99(10):1137-9
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  • [Title] Cutaneous metastases of signet cell carcinoma of the rectum without accompanying visceral involvement.
  • Cutaneous metastasis of rectal carcinoma is a rare event.
  • It occurs in fewer than 4% of all patients with rectal cancer.
  • Although skin metastasis of rectal cancer is usually detected around surgical scars or on the abdominal wall, especially in the periumbilical region, it rarely presents at other sites.
  • The early diagnosis of skin metastases in these patients is very important because it can alter treatment.
  • A case of signet cell carcinoma of the rectum with cutaneous metastases without accompanying visceral involvement is presented, occurring 14 months after completion of adjuvant therapy.
  • [MeSH-major] Carcinoma, Signet Ring Cell / secondary. Rectal Neoplasms / pathology. Skin Neoplasms / secondary

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  • (PMID = 17100038.001).
  • [ISSN] 0038-4348
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Afroza A, Hasan S, Rukunuzzaman M, Hussain SA, Amin R: Carcinoma-rectum in an 11 years old boy. Mymensingh Med J; 2007 Jul;16(2 Suppl):S70-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoma-rectum in an 11 years old boy.
  • Carcinoma rectum is a very uncommon malignancy in childhood.
  • The incidence of colon cancer is found to be 1.3 cases per million children.
  • An eleven years old boy with carcinoma rectum was admitted in the Department of Paediatric Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU).
  • The rectal wall was tender and hard mass could be felt in the surrounding area on direct rectal examination.
  • Diagnosis was confirmed by biopsy of the tissue from the growth.
  • Since carcinoma rectum in children has not been reported in Bangladesh we share the information with professionals.

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  • (PMID = 17917638.001).
  • [ISSN] 1022-4742
  • [Journal-full-title] Mymensingh medical journal : MMJ
  • [ISO-abbreviation] Mymensingh Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Bangladesh
  • [Chemical-registry-number] Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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35. Wang H, Cao FA, Gong HF, Zheng JM, Fu CG: Could tumor characteristics identified by colonoscopy predict the locally advanced rectal carcinoma? Chin Med J (Engl); 2010 Sep;123(17):2353-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Could tumor characteristics identified by colonoscopy predict the locally advanced rectal carcinoma?
  • BACKGROUND: Neoadjuvant chemoradiation is now considered the standard care for locally advanced rectal carcinoma (T3-4 or/and N1-2 lesions), but the accuracy of staging examinations including endorectal ultrasonography (ERUS) and MRI is far from excellent.
  • The objective of the present study was to investigate the clinical and pathological characteristics of locally advanced rectal carcinoma and identify candidates for neoadjuvant chemoradiation.
  • Patients who were treated for rectal cancer at Changhai Hospital from January 1999 to July 2008 were identified from our prospectively collected database.
  • RESULTS: A total of 1005 cases were included in this research, of which 761 cases were identified as locally advanced rectal carcinoma depending on postoperative TNM staging.
  • The results of multivariate Logistic regression analysis indicated seven independent risk factors that could be used to predict a locally advanced rectal carcinoma independently: a high grade (including poor differentiation and undifferentiation) (OR: 3.856; 95% CI: 2.064 to 7.204; P = 0.000); large tumor size (OR: 2.455; 95% CI: 1.755 to 3.436; P = 0.000); elevated preoperative serum CEA level (OR: 1.823; 95% CI: 1.309 to 2.537; P = 0.000); non-polypoid tumor type (OR: 1.758; 95% CI: 1.273 to 2.427; P = 0.001); the absence of synchronous polyps (OR: 1.602; 95% CI: 1.103 to 2.327; P = 0.013); the absence of blood in stool (OR: 1.659; 95% CI: 1.049 to 2.624; P = 0.030); and a greater circumferential tumor extent (OR: 1.813; 95% CI: 1.055 to 3.113; P = 0.031).
  • CONCLUSIONS: Some independent risk factors related with locally advanced rectal carcinoma were identified, based on which it is possible to establish a Logistic equation as a tool to predict candidates of neoadjuvant chemoradiation.
  • [MeSH-major] Colonoscopy / methods. Rectal Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Endosonography. Female. Humans. Logistic Models. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Staging. Retrospective Studies

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  • (PMID = 21034548.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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36. Merkel S, Mansmann U, Hohenberger W, Hermanek P: [Uniform calculation of local recurrence rates--requirement for quality management in rectal carcinoma]. Z Arztl Fortbild Qualitatssich; 2006;100(3):183-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Uniform calculation of local recurrence rates--requirement for quality management in rectal carcinoma].
  • The local recurrence rate is an important indicator in the quality management of rectal carcinoma.
  • The data of the German Study Group for Colorectal Carcinoma (SGCRC) and the Erlangen Registry for Colorectal Carcinoma (ERCRC) were used to demonstrate the influence of different calculation methods on the level of local recurrence rates.
  • [MeSH-major] Disease Management. Neoplasm Recurrence, Local / epidemiology. Quality of Life. Rectal Neoplasms / pathology

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  • (PMID = 16768083.001).
  • [ISSN] 1431-7621
  • [Journal-full-title] Zeitschrift für ärztliche Fortbildung und Qualitätssicherung
  • [ISO-abbreviation] Z Arztl Fortbild Qualitatssich
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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37. Ptok H, Marusch F, Meyer F, Wendling P, Wenisch HJ, Sendt W, Manger T, Lippert H, Gastinger I: Feasibility and accuracy of TRUS in the pre-treatment staging for rectal carcinoma in general practice. Eur J Surg Oncol; 2006 May;32(4):420-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Feasibility and accuracy of TRUS in the pre-treatment staging for rectal carcinoma in general practice.
  • AIMS: Transrectal ultrasonography (TRUS) is the diagnostic tool of choice for local staging of rectal carcinoma.
  • PATIENTS AND METHODS: From 01/01/2000 to 12/31/2003, all patients with rectal carcinoma were enrolled in a prospective multicenter observational study.
  • RESULTS: Overall, 13,610 patients with rectal carcinoma were enrolled in the study.
  • In discriminating tumour growth limited to the rectal wall vs that through the rectal wall into the neighboring tissue, TRUS-associated accuracy was 76.5%.
  • CONCLUSIONS: Diagnostic accuracy of TRUS in determining depth of tumour infiltration within or through the rectum wall in the routinuous diagnostic of rectal carcinoma does not reach the excellent published study results.
  • [MeSH-major] Carcinoma / pathology. Carcinoma / ultrasonography. Endosonography. Family Practice. Neoplasm Staging / methods. Rectal Neoplasms / pathology. Rectal Neoplasms / ultrasonography

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  • (PMID = 16520014.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] England
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38. Moral M, Fdez-Aceñero MJ, Cuberes R, Suárez A: Factors influencing prognosis after neo-adjuvant chemoradiation therapy for rectal carcinoma. Acta Chir Belg; 2009 May-Jun;109(3):345-51
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  • [Title] Factors influencing prognosis after neo-adjuvant chemoradiation therapy for rectal carcinoma.
  • BACKGROUND: Neo-adjuvant chemoradiation therapy (CRTx) has become a standard therapeutic regimen for rectal carcinoma.
  • This therapeutic option allows more sphincter preserving surgical procedures and seems to improve prognosis in patients with rectal carcinoma.
  • CONCLUSION: In our series of patients with rectal carcinoma receiving pre-operative chemoradiation therapy, histopathological response has influenced prognosis.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Rectal Neoplasms / radiotherapy

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  • (PMID = 19943591.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Belgium
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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39. Rosenberg R, Nekarda H, Zimmermann F, Becker K, Lordick F, Hofler H, Molls M, Siewert JR: Histopathological response after preoperative radiochemotherapy in rectal carcinoma is associated with improved overall survival. J Surg Oncol; 2008 Jan 1;97(1):8-13

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Histopathological response after preoperative radiochemotherapy in rectal carcinoma is associated with improved overall survival.
  • BACKGROUND: Recent studies showed improved local control after preoperative radiochemotherapy (RCTX) in patients with locally advanced rectal carcinoma, but failed to demonstrate a survival benefit.
  • METHODS: One hundred four patients with uT3 rectal carcinoma were treated with preoperative RCTX of 45 Gy and continuous 5-FU infusion between 1997 and 2001 (group I).
  • Group II consisted of 114 patients with uT3 rectal carcinoma treated with postoperative RCTX between 1988 and 1997.
  • [MeSH-major] Rectal Neoplasms / therapy

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 18085619.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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40. Zhao DB, Gao JD, Bi JJ, Shao YF, Zhao P: [Lymph node metastasis and prognosis in T1 and T2 rectal carcinoma]. Zhonghua Zhong Liu Za Zhi; 2006 Mar;28(3):235-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Lymph node metastasis and prognosis in T1 and T2 rectal carcinoma].
  • OBJECTIVE: To investigate the characteristics of lymph node metastasis and prognosis of T1/T2 rectal carcinoma.
  • METHODS: The clinical data of 241 patients with T1 or T2 rectal carcinoma were retrospectively analyzed.
  • CONCLUSION: Even though lymph node metastasis can be observed either in T1 or T2 rectal carcinoma, histological differentiation is significantly related to the lymph node metastasis.
  • As radical resection achieve better survival than local resection, it should be suggested as the chief treatment for T1/T2 rectal carcinoma.
  • [MeSH-major] Carcinoma, Ductal / surgery. Lymph Nodes / pathology. Rectal Neoplasms / surgery. Rectum / surgery
  • [MeSH-minor] Adenocarcinoma, Mucinous / radiotherapy. Adenocarcinoma, Mucinous / secondary. Adenocarcinoma, Mucinous / surgery. Adult. Aged. Aged, 80 and over. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Proportional Hazards Models. Radiotherapy, Adjuvant. Retrospective Studies. Survival Rate

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  • (PMID = 16875615.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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41. Cao J, Xia J, Wang H, DU H, Li WL: [Fragile histidine triad protein expression and correlation with apoptosis in rectal carcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2007 Mar;10(2):177-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Fragile histidine triad protein expression and correlation with apoptosis in rectal carcinoma].
  • OBJECTIVE: To investigate the relationship between the expression of fragile histidine triad (FHIT) protein and the clinicopathological characteristics of rectal carcinoma.
  • The relationship between FHIT protein expression and Bcl-2, Bax and survivin expression, as well as cell apoptosis in rectal carcinoma were explored.
  • METHODS: Tissue microarray and immunohistochemistry SP were used to detect the expression of FHIT, Bcl-2, Bax and Survivin in 16 cases of normal rectal tissue, 16 cases of rectal adenoma and 80 cases of rectal carcinoma.
  • TUNEL was used to detect apoptosis index (AI) in 80 cases of rectal carcinoma.
  • RESULTS: The positive rates of FHIT expression in normal rectal tissue, rectal adenoma and adenocarcinoma were 93.8%, 75.0% and 46.3% respectively.
  • The expression of FHIT was positively correlated with that of Bcl-2, Bax and survivin in rectal cancer.
  • CONCLUSIONS: The reduction of FHIT protein expression may play an important role in the development of rectal carcinoma, and FHIT protein may be associated with the regulation of cell apoptosis.
  • [MeSH-major] Acid Anhydride Hydrolases / metabolism. Apoptosis. Neoplasm Proteins / metabolism. Rectal Neoplasms / metabolism. Rectal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Inhibitor of Apoptosis Proteins. Lymphatic Metastasis. Male. Microtubule-Associated Proteins / metabolism. Middle Aged. Neoplasm Staging. Protein Array Analysis. bcl-2-Associated X Protein / metabolism

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  • (PMID = 17380463.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / BIRC5 protein, human; 0 / Inhibitor of Apoptosis Proteins; 0 / Microtubule-Associated Proteins; 0 / Neoplasm Proteins; 0 / bcl-2-Associated X Protein; 0 / fragile histidine triad protein; EC 3.6.- / Acid Anhydride Hydrolases
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42. Junginger T, Hermanek P: [Problems in the treatment of upper rectal carcinoma]. Chirurg; 2008 Apr;79(4):327-39
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  • [Title] [Problems in the treatment of upper rectal carcinoma].
  • In the literature there is some disagreement about the treatment of upper rectal carcinoma (aboral margin 12-16 cm from the anocutaneous line), in particular about the necessary extent of mesorectal excision and the indications for neoadjuvant and adjuvant therapy.
  • The special pathologic features of upper rectal carcinomas (lymphatic spread, distal tumor spread beyond the gross margin) and present clinical experiences are discussed.
  • [MeSH-minor] Algorithms. Chemotherapy, Adjuvant. Combined Modality Therapy. Humans. Lymph Nodes / pathology. Lymphatic Metastasis / pathology. Neoadjuvant Therapy. Neoplasm Invasiveness. Neoplasm Staging. Practice Guidelines as Topic. Radiotherapy, Adjuvant. Rectum / pathology. Rectum / surgery

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  • (PMID = 18274715.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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43. Moral M, Fdez-Aceñero MA, Cuberes R, Suárez A: Factors influencing histological response after neoadjuvant chemoradiation therapy for rectal carcinoma. Pathol Res Pract; 2009;205(10):695-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Factors influencing histological response after neoadjuvant chemoradiation therapy for rectal carcinoma.
  • Neoadjuvant chemoradiation therapy is one of the standard therapeutic regimens for rectal carcinoma.
  • In our series of patients with rectal carcinoma receiving preoperative chemoradiation therapy, few factors were predictive of a histological response.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoadjuvant Therapy. Rectal Neoplasms / pathology. Rectal Neoplasms / therapy
  • [MeSH-minor] Age Factors. Antineoplastic Agents / therapeutic use. Carcinoembryonic Antigen / blood. Combined Modality Therapy. Cyclin D1 / biosynthesis. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Proto-Oncogene Proteins c-bcl-2 / biosynthesis. Radiotherapy. Risk Factors. Treatment Outcome. Tumor Suppressor Protein p53 / biosynthesis. Ubiquitin-Protein Ligases / biosynthesis

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  • (PMID = 19446404.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Tumor Suppressor Protein p53; 136601-57-5 / Cyclin D1; EC 6.3.2.19 / MIB1 ligase, human; EC 6.3.2.19 / Ubiquitin-Protein Ligases
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44. Greco P, Magro G: Pathologic examination and staging of rectal carcinoma: a critical review. Pathologica; 2010 Feb;102(1):12-27

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathologic examination and staging of rectal carcinoma: a critical review.
  • In rectal carcinoma, accurate pathological examination is crucial for a correct staging and identification of predictors of risk of both local recurrence and overall survival.
  • Accordingly, surgical pathologists determine many facets of rectal carcinoma patient care.
  • Although rectal carcinoma shares many pathologic features with colon carcinoma, however, the anatomical location of the rectum poses additional problems in formulation of a pathological report.
  • The most critical issues of pathological examination in rectal carcinoma involve assessment of: i) surgical resection margins (distal and circumferential resection margins);.
  • The aim of this critical review on rectal carcinoma is to discuss confusing and/or challenging pathological problems, especially those with clinical impact, in order to provide a checklist that is useful for practicing surgical pathologists.
  • [MeSH-major] Rectal Neoplasms / pathology
  • [MeSH-minor] Combined Modality Therapy. Digestive System Surgical Procedures. Humans. Lymph Nodes / pathology. Lymph Nodes / surgery. Neoplasm Metastasis. Neoplasm Staging. Rectum / pathology. Rectum / surgery

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  • (PMID = 20731249.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 146
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45. Zhuang CP, Cai GY, Li TH, Wang YQ, Chen WR: [Efficacy evaluation of intersphincteric resection during anus-preserving operation for ultralow rectal carcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2009 Jul;12(4):364-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Efficacy evaluation of intersphincteric resection during anus-preserving operation for ultralow rectal carcinoma].
  • OBJECTIVE: To evaluate anorectal dynamics, function and efficacy of ultralow rectal carcinoma patients undergone intersphincteric resection(ISR).
  • METHODS: From January 2004 to August 2007, 30 patients with ultralow rectal carcinoma(2.5-4.0 cm distance from anal edge) underwent ISR.
  • RESULTS: After ISR operation, anal resting pressure, maximum squeeze pressure and maximum tolerance volume of the rectum decreased significantly (all P<0.01) and restored gradually, but not to normal.
  • The rectal anal inhibitory reflex disappeared in 27 patients(90.0%) and was not improved.
  • CONCLUSION: ISR for ultralow rectal carcinoma can not only attain radical treatment outcome, but also preserve anal sphincter.
  • [MeSH-major] Anal Canal / surgery. Anastomosis, Surgical / methods. Digestive System Surgical Procedures. Rectal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Rectum / surgery. Treatment Outcome

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  • (PMID = 19598020.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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46. Saito H, Shuto K, Ohira G, Natsume T, Narushima K, Sato A, Ota T, Sakata H, Miyauchi H, Matsubara H: [Evaluation of preoperative chemoradiation therapy for lower rectal carcinoma using DWIBS]. Gan To Kagaku Ryoho; 2009 Nov;36(12):2146-8
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  • [Title] [Evaluation of preoperative chemoradiation therapy for lower rectal carcinoma using DWIBS].
  • We investigated the efficacy of diffusion-weighed whole body imaging with background body signal suppression (DWIBS) in assessing effects of chemoradiation therapy (CRT) on rectal carcinoma.
  • DWIBS was performed in patients (n=12) with primary rectal carcinoma undergoing preoperative CRT before and 3 weeks after the treatment.
  • These preliminary results indicate that DWIBS may be a valuable tool to assess effects of CRT on rectal carcinoma by using appropriate cut-off values.
  • [MeSH-major] Diffusion Magnetic Resonance Imaging. Rectal Neoplasms / diagnosis. Rectal Neoplasms / therapy

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  • (PMID = 20037351.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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47. Matsuoka H, Masaki T, Sugiyama M, Atomi Y, Ohkura Y, Sakamoto A: Morphological characteristics of lateral pelvic lymph nodes in rectal carcinoma. Langenbecks Arch Surg; 2007 Sep;392(5):543-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphological characteristics of lateral pelvic lymph nodes in rectal carcinoma.
  • AIM: Macroscopic and imaging indicators for lymph node metastasis have been documented not in lateral pelvic lymph nodes but in mesorectal lymph nodes in patients with rectal carcinoma.
  • We conducted this study to uncover morphological characteristics of lateral pelvic lymph nodes in patients with rectal carcinoma.
  • MATERIALS AND METHODS: Fifty-eight patients with locally advanced rectal carcinoma who had total mesorectal excision and lateral pelvic lymph node dissection were studied.
  • [MeSH-major] Lymph Nodes / pathology. Lymphatic Metastasis / pathology. Rectal Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Lymph Node Excision. Multivariate Analysis. Neoplasm Staging. Prognosis. ROC Curve. Rectum / pathology. Rectum / surgery. Risk Factors

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  • (PMID = 17380345.001).
  • [ISSN] 1435-2451
  • [Journal-full-title] Langenbeck's archives of surgery
  • [ISO-abbreviation] Langenbecks Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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48. Lin GL, Qiu HZ, Xiao Y, Wu B, Meng WC: [Transanal endoscopic microsurgery for rectal intraepithelial neoplasia and early rectal carcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2008 Jan;11(1):39-43

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Transanal endoscopic microsurgery for rectal intraepithelial neoplasia and early rectal carcinoma].
  • OBJECTIVE: To investigate the clinical value of transanal endoscopic microsurgery (TEM) for rectal intraepithelial neoplasia (IN) and early rectal carcinoma.
  • METHODS: Fifteen patients with rectal tumor were selected to undergo local excision by TEM.
  • The pre-operative diagnosis by biopsy and endoanal ultrasonography (EUS): rectal low-grade IN in 8 cases, high-grade IN in 4 and early rectal carcinoma in 3.
  • RESULTS: All the 15 rectal tumors were achieved complete excision (submucosal excision in 5, full-thickness excision in 10), and all the resection margins were clear.
  • The post-operative pathological diagnosis: rectal low-grade IN in 5 cases, high-grade IN in 6, early submucous invasive carcinoma (pT(1)) in 2, advanced carcinoma (pT(2)) in 2.
  • The diagnostic accuracy of EUS in assessing invasive depth of rectal tumor was 86.7% (13/15).
  • CONCLUSION: TEM is an ideal minimally invasive procedure for the treatment of rectal IN and early rectal carcinoma, with excellent exposure and accurate excision, providing a high-quality tumor specimen for pathological staging.
  • [MeSH-major] Anal Canal / surgery. Microsurgery. Rectal Neoplasms / surgery. Rectum / surgery

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  • (PMID = 18197492.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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49. Cui CY, Li L, Liu LZ: [Value of multislice spiral CT in preoperative staging of rectal carcinoma]. Ai Zheng; 2008 Feb;27(2):196-200

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Value of multislice spiral CT in preoperative staging of rectal carcinoma].
  • BACKGROUND & OBJECTIVE: Preoperative staging is important for optimal therapy planning and prognosis prediction of rectal carcinoma.
  • The role of conventional computed tomography (CT) in preoperative staging of rectal carcinoma is controversial.
  • This study was to evaluate the value of multislice spiral computed tomography (MSCT) in preoperative staging of rectal carcinoma.
  • 2007, 87 patients with pathologically proved rectal cancer underwent preoperative plain and enhanced MSCT.
  • Two radiologists evaluated independently tumor location, size, the depth of tumor invasion into the rectal wall (T), the involvement of regional lymph nodes (N) and the presence of distant metastases (M) on CT images.
  • RESULTS: All the 87 cases of rectal carcinoma were detected clearly by MSCT.
  • CONCLUSION: MSCT is an accurate technique for preoperative staging of rectal carcinoma, which can assess the extension to adjacent tissues and the presence of lymph node and distant metastases exactly.
  • [MeSH-major] Rectal Neoplasms / pathology. Rectal Neoplasms / radiography. Tomography, Spiral Computed / methods
  • [MeSH-minor] Adult. Aged. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 18279621.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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50. Schiedeck T: [Principles and quality control of surgical therapy of rectal carcinoma]. MMW Fortschr Med; 2007 Jun 7;149(23):29-32
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  • [Title] [Principles and quality control of surgical therapy of rectal carcinoma].
  • During the past years, it has been possible to achieve impressive success in the treatment of rectal carcinoma through standardized therapeutic concepts.
  • [MeSH-major] Quality Assurance, Health Care. Rectal Neoplasms / surgery
  • [MeSH-minor] Anal Canal / pathology. Anal Canal / surgery. Anastomosis, Surgical / methods. Colonic Pouches. Colostomy / methods. Colostomy / psychology. Follow-Up Studies. Humans. Neoplasm Recurrence, Local / mortality. Neoplasm Staging. Quality Control. Quality of Life. Risk. Survival Rate

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  • (PMID = 18062574.001).
  • [ISSN] 1438-3276
  • [Journal-full-title] MMW Fortschritte der Medizin
  • [ISO-abbreviation] MMW Fortschr Med
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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51. Appu S, Lawrentschuk N, Russell JM, Bright NF: Metachronous metastasis to the penis from carcinoma of the rectum. Int J Urol; 2006 May;13(5):659-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metachronous metastasis to the penis from carcinoma of the rectum.
  • Furthermore, very few cases exist where primary rectal carcinoma metastasising to the penis has been reported.
  • [MeSH-major] Adenocarcinoma / pathology. Penile Neoplasms / pathology. Penile Neoplasms / secondary. Rectal Neoplasms / pathology

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  • (PMID = 16771752.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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52. Guzińska-Ustymowicz K: The role of tumour budding at the front of invasion and recurrence of rectal carcinoma. Anticancer Res; 2005 Mar-Apr;25(2B):1269-72

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of tumour budding at the front of invasion and recurrence of rectal carcinoma.
  • The presence of "tumour budding", ie. single cancer cells, or a nest of poorly- differentiated cells at the front of invasion, in bowel cancer appears to be a new histopathological indicator of increased aggressiveness of colorectal carcinoma.
  • The aim of this work was a retrospective evaluation of the front of invasion in preoperative biopsies of patients with rectal carcinoma (T1) and an analysis of the relationship between tumour budding and metastases or recurrence of the tumour at the site of resection.
  • PATIENTS AND METHODS: The study was performed based on material obtained before and during surgical treatment of 34 patients with cancer of the colon.
  • CONCLUSION: The results suggest the usefulness of evaluating TB at the front of invasion as an additional prognostic indicator in rectal carcinoma.
  • [MeSH-major] Rectal Neoplasms / pathology
  • [MeSH-minor] Biopsy. Humans. Lymphatic Metastasis. Neoplasm Metastasis. Neoplasm Recurrence, Local. Neovascularization, Pathologic. Prognosis. Retrospective Studies

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  • (PMID = 15865077.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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53. Ju HX, Li DC, Xu D, Qian CW, Tian PL: [Comparative study of endoluminal ultrasonography and spiral computed tomography in preoperative staging of rectal carcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2006 Nov;9(6):495-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Comparative study of endoluminal ultrasonography and spiral computed tomography in preoperative staging of rectal carcinoma].
  • OBJECTIVE: To compare the efficacy of endoluminal ultrasonography (EUS) and spiral computed tomography (SCT) in preoperative staging of rectal carcinoma.
  • METHODS: Both EUS and SCT were performed prior to surgery in 68 patients with rectal carcinoma.
  • After radical surgery, the preoperative findings were compared with histologic findings of the operative specimens, and the efficacy of EUS and SCT in staging the rectal carcinoma were evaluated.
  • [MeSH-major] Neoplasm Staging / methods. Rectal Neoplasms / radiography. Rectal Neoplasms / ultrasonography

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  • (PMID = 17143793.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] China
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54. Stocchi L, Nelson H, Sargent DJ, Engen DE, Haddock MG: Is en-bloc resection of locally recurrent rectal carcinoma involving the urinary tract indicated? Ann Surg Oncol; 2006 May;13(5):740-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is en-bloc resection of locally recurrent rectal carcinoma involving the urinary tract indicated?
  • BACKGROUND: This study investigated morbidity, mortality, and long-term survival after multimodality management of locally recurrent rectal carcinoma involving the urinary tract.
  • CONCLUSIONS: A multimodality approach for locally recurrent rectal carcinoma involving the urinary tract carries acceptable morbidity, mortality, and potential for long-term survival.
  • [MeSH-major] Reconstructive Surgical Procedures / methods. Rectal Neoplasms / pathology. Rectal Neoplasms / surgery. Urologic Neoplasms / secondary. Urologic Neoplasms / surgery
  • [MeSH-minor] Aged. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Pelvic Exenteration. Postoperative Complications. Proportional Hazards Models. Registries. Retrospective Studies. Survival Rate. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.
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  • (PMID = 16523359.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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55. Messiou C, Chalmers A, Boyle K, Sagar P: Surgery for recurrent rectal carcinoma: The role of preoperative magnetic resonance imaging. Clin Radiol; 2006 Mar;61(3):250-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgery for recurrent rectal carcinoma: The role of preoperative magnetic resonance imaging.
  • Despite apparent curative resection of rectal carcinoma, local recurrence rates of between 3 and 32% have been reported.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Neoplasm Recurrence, Local / diagnosis. Rectal Neoplasms / diagnosis
  • [MeSH-minor] Humans. Neoplasm Staging / methods. Preoperative Care / methods

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  • (PMID = 16488206.001).
  • [ISSN] 0009-9260
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 47
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56. Lygidakis NJ, Safioleas M: Multimodality approach towards advanced rectal carcinoma. "Its efficacy and safety". Hepatogastroenterology; 2005 Mar-Apr;52(62):385-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multimodality approach towards advanced rectal carcinoma. "Its efficacy and safety".
  • BACKGROUND/AIMS: To evaluate the efficacy and safety of multimodality approach towards advanced rectal cancer.
  • METHODOLOGY: In a prospective, randomized trial, two hundred and ten patients with advanced carcinoma of the rectum were studied.
  • CONCLUSIONS: Multimodality approach to advanced rectal cancer leads to substantial prolongation of survival and optimization of quality of life.
  • [MeSH-major] Carcinoma / surgery. Rectal Neoplasms / surgery

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  • (PMID = 15816442.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial
  • [Publication-country] Greece
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57. Noda E, Maeda K, Inoue T, Nishihara T, Nishiguchi Y, Ohira M, Hirakawa K: Predictive value of vascular endothelial growth factor-C expression for local recurrence of rectal carcinoma. Oncol Rep; 2007 Jun;17(6):1327-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictive value of vascular endothelial growth factor-C expression for local recurrence of rectal carcinoma.
  • There have been reports of a positive correlation between local recurrence of rectal carcinoma and lymphatic invasion by the tumor.
  • The aim of this study was to determine the clinical significance of VEGF-C expression for identifying lymphangiogenesis as a predictor of the local recurrence of rectal carcinoma.
  • One hundred surgical specimens of rectal carcinoma from patients with (n=26) or without (n=74) local recurrence were studied.
  • Moreover, multivariate analysis showed that VEGF-C protein expression was an independent risk factor for the local recurrence of rectal carcinoma, and patients with VEGF-C positive tumors had a significantly worse prognosis than those with VEGF-C negative tumors.
  • Expression of VEGF-C may be a good predictor of the local recurrence of rectal carcinoma and may also be a useful prognostic indicator.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoplasm Recurrence, Local / diagnosis. Rectal Neoplasms / diagnosis. Vascular Endothelial Growth Factor C / analysis

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  • (PMID = 17487386.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vascular Endothelial Growth Factor C
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58. Feng HY, Li DC, Lou RC, Zhu Y, Liu LY: [Preoperative chemoradiotherapy as neoadjuvant therapy for 35 patients with locally advanced lower rectal carcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2005 Mar;8(2):125-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Preoperative chemoradiotherapy as neoadjuvant therapy for 35 patients with locally advanced lower rectal carcinoma].
  • OBJECTIVE: To explore the effect of combined preoperative chemotherapy with radiotherapy on locally advanced lower rectal carcinoma.
  • METHODS: Thirty- five patients with locally advanced lower rectal carcinoma were received a new regimen of combined preoperative chemotherapy with radiotherapy.
  • CONCLUSION: Combined preoperative chemotherapy with radiotherapy is a better neoadjuvant therapy for lower advanced rectal cancer,which can decrease tumor stage,improve resectability and anal sphincter preservation rate,therefore ,this new neoadjuvant therapy with tolerable toxicity will has a promising application in the clinical setting.
  • [MeSH-major] Neoadjuvant Therapy. Rectal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Chemotherapy, Adjuvant. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Radiotherapy, Adjuvant. Treatment Outcome

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  • (PMID = 16155821.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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59. Kayaçetin E, Kayaçetin S: Colitis cystica profunda simulating rectal carcinoma. Acta Chir Belg; 2005 May-Jun;105(3):306-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colitis cystica profunda simulating rectal carcinoma.
  • Localized colitis cystica profunda is a rare, benign disease of the lower gastro-intestinal tract, usually presenting as a rectal mass and characterized microscopically by the presence of mucus-filled cysts in the submucosa.
  • Knowledge of this particular pathological entity is important as it can mimic a well differentiated adenocarcinoma of the rectum and therefore could lead to unnecessary surgical resection.
  • We present a case of colitis cystica profunda misdiagnosed as adenocarcinoma based on their similar clinical picture and histological features.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Colitis / diagnosis. Colitis / pathology. Cysts / diagnosis. Cysts / pathology. Rectal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 16018526.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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60. Anthonioz-Lescop C, Aubé C, Luet D, Lermite E, Burtin P, Ridereau-Zins C: [MR-endoscopic US correlation for loco-regional staging of rectal carcinoma]. J Radiol; 2007 Dec;88(12):1865-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [MR-endoscopic US correlation for loco-regional staging of rectal carcinoma].
  • [Transliterated title] Corrélation IRM-échoendoscopie dans le bilan d'extension locorégional initial du cancer du rectum.
  • INTRODUCTION: To correlate findings at high-resolution MR and endoscopic US (EUS) for preoperative loco-regional staging of rectal carcinoma.
  • PATIENTS AND METHODS: Fifty-two patients with rectal carcinoma underwent high-resolution MR imaging.
  • Results confirm that high-resolution MRI is useful for loco-regional staging of rectal carcinoma, especially for large tumors.
  • EUS should be limited to the valuation of superficial tumors of the rectum.
  • [MeSH-major] Carcinoma / pathology. Endosonography / methods. Magnetic Resonance Imaging / methods. Rectal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Constriction, Pathologic / pathology. Contrast Media. Fascia / pathology. Fascia / surgery. Female. Humans. Image Enhancement. Lymphatic Metastasis / pathology. Male. Middle Aged. Neoadjuvant Therapy. Neoplasm Invasiveness. Neoplasm Staging. Predictive Value of Tests. Prospective Studies. Radiotherapy, Adjuvant. Rectum / pathology. Rectum / surgery

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  • [CommentIn] J Radiol. 2007 Dec;88(12):1839-41 [18235343.001]
  • (PMID = 18235347.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
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61. Melichar B, Ryska A, Krepelová A, Holecková P: Rectal carcinoma after radiotherapy for cervical carcinoma in patients with a family history of colorectal carcinoma: report of two cases. Eur J Gynaecol Oncol; 2007;28(4):319-21
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  • [Title] Rectal carcinoma after radiotherapy for cervical carcinoma in patients with a family history of colorectal carcinoma: report of two cases.
  • Rectal carcinoma is a rare, but well documented late complication of pelvic irradiation.
  • Little is known about the factors predisposing to the development of radiation-associated rectal carcinoma.
  • We present two patients who developed rectal carcinoma 17 and 26 years after radiotherapy for carcinoma of the uterine cervix.
  • Radiation-associated rectal carcinoma represents a rare late toxicity of radiotherapy for cervical carcinoma that may occur in patients with a family history of colorectal carcinoma, including hereditary non-polyposis colorectal cancer.
  • [MeSH-major] Adaptor Proteins, Signal Transducing / genetics. Neoplasms, Radiation-Induced / genetics. Nuclear Proteins / genetics. Radiotherapy / adverse effects. Rectal Neoplasms / etiology. Uterine Cervical Neoplasms / radiotherapy

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  • (PMID = 17713103.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / MLH1 protein, human; 0 / Nuclear Proteins
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62. Zhao DB, Bi JJ, Gao JD, Shao YF, Zhao P: [Analysis of recurrence and prognosis after surgical resection for I stage lower rectal carcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2006 Mar;9(2):117-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of recurrence and prognosis after surgical resection for I stage lower rectal carcinoma].
  • OBJECTIVE: To investigate the clinicopathologic factors related with recurrence and prognosis after surgical resection for I stage lower rectal carcinoma.
  • METHODS: The related clinicopathologic factors for recurrence and prognosis of 166 patients with I stage lower rectal carcinoma after surgical resection were retrospectively analyzed using univariate and multivariate methods.
  • RESULTS: A total of 138 patients with I stage lower rectal carcinoma received radical resection according to the operative rules of total mesorectal excision (TME).
  • Multivariate analysis revealed that local recurrence was the most important prognostic factor for I stage lower rectal carcinoma.
  • CONCLUSIONS: Radical resection of I stage lower rectal carcinoma has low recurrence rate and better prognosis.
  • [MeSH-major] Neoplasm Recurrence, Local. Rectal Neoplasms / pathology. Rectal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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  • (PMID = 16555148.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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63. Jacques AE, Rockall AG, Alijani M, Hughes J, Babar S, Aleong JA, Cottrill C, Dorudi S, Reznek RH: MRI demonstration of the effect of neoadjuvant radiotherapy on rectal carcinoma. Acta Oncol; 2007;46(7):989-95
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  • [Title] MRI demonstration of the effect of neoadjuvant radiotherapy on rectal carcinoma.
  • BACKGROUND AND PURPOSE: In patients with locally advanced rectal cancer, neoadjuvant long course (45-54 Gy in 25-30 fractions) chemoradiotherapy (CRT) may reduce tumour size and result in downstaging.
  • MATERIALS AND METHODS: Nineteen patients with rectal carcinoma underwent MRI before and after SCRT or CRT.
  • [MeSH-major] Carcinoma / diagnosis. Carcinoma / radiotherapy. Magnetic Resonance Imaging. Rectal Neoplasms / diagnosis. Rectal Neoplasms / radiotherapy

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  • (PMID = 17851843.001).
  • [ISSN] 0284-186X
  • [Journal-full-title] Acta oncologica (Stockholm, Sweden)
  • [ISO-abbreviation] Acta Oncol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Norway
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64. Mersich T, Lang I, Balogh I, Jakab F: Radio-guided resection of non-palpable rectal carcinoma following polypectomy. Hepatogastroenterology; 2007 Apr-May;54(75):751-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radio-guided resection of non-palpable rectal carcinoma following polypectomy.
  • Due to widespread use of screening procedures for colorectal cancer, an increasing number of colorectal malignancies is diagnosed at an early stage.
  • A special subgroup of these patients has polyp carcinoma, which can be diagnosed with histological examination of the removed specimen.
  • In our case report, radio-labeled colloid was used to identify non-palpable rectal carcinoma after polypectomy in a high risk patient.
  • [MeSH-major] Carcinoma / radionuclide imaging. Carcinoma / surgery. Digestive System Surgical Procedures. Intestinal Polyps / complications. Rectal Neoplasms / radionuclide imaging. Rectal Neoplasms / surgery

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  • (PMID = 17591054.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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65. Hermanek P, Junginger T: The circumferential resection margin in rectal carcinoma surgery. Tech Coloproctol; 2005 Dec;9(3):193-9; discussion 199-200

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The circumferential resection margin in rectal carcinoma surgery.
  • After radical resection of rectal carcinoma, the circumferential resection margin (CRM) on the non-peritonealized surface of the resected specimen is of critical importance.
  • [MeSH-major] Colectomy / methods. Neoplasm Invasiveness / pathology. Neoplasm Recurrence, Local / pathology. Rectal Neoplasms / pathology. Rectal Neoplasms / surgery
  • [MeSH-minor] Biopsy, Needle. Colonoscopy / methods. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Neoadjuvant Therapy / methods. Neoplasm Staging. Predictive Value of Tests. Preoperative Care. Prognosis. Risk Assessment. Sensitivity and Specificity. Survival Analysis. Treatment Outcome

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  • (PMID = 16328130.001).
  • [ISSN] 1123-6337
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 14
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66. Kneist W, Heintz A, Junginger T: Major urinary dysfunction after mesorectal excision for rectal carcinoma. Br J Surg; 2005 Feb;92(2):230-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Major urinary dysfunction after mesorectal excision for rectal carcinoma.
  • BACKGROUND: Urinary dysfunction may occur after mesorectal excision and pelvic autonomic nerve preservation (PANP) in patients with rectal carcinoma.
  • METHODS: Two hundred and ten patients without significant urological problems underwent resection of rectal cancer with mesorectal excision.
  • CONCLUSION: Major urinary dysfunction after mesorectal excision for rectal cancer is associated with an incomplete nerve-sparing technique.
  • [MeSH-major] Postoperative Complications / etiology. Rectal Neoplasms / surgery. Urination Disorders / etiology

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  • (PMID = 15609379.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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67. Nojima H, Seike K, Kosugi C, Shida T, Koda K, Oda K, Kamata S, Ishikura H, Miyazaki M: Advanced moderately differentiated neuroendocrine carcinoma of the rectum with favorable prognosis by postoperative chemoradiation. World J Surg Oncol; 2010;8:29
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  • [Title] Advanced moderately differentiated neuroendocrine carcinoma of the rectum with favorable prognosis by postoperative chemoradiation.
  • Rectal neuroendocrine carcinoma is rare with poor prognosis.
  • We report herein a case of advanced moderately differentiated neuroendocrine carcinoma of the rectum with relatively favorable prognosis treated by postoperative adjuvant chemoradiation therapy.
  • A 58-year-old Japanese female was referred and colonofiberscopy revealed an easy-bleeding irregular tumor in the lower rectum, which was pathologically diagnosed as a neuroendocrine carcinoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Neuroendocrine / drug therapy. Carcinoma, Neuroendocrine / radiotherapy. Rectal Neoplasms / drug therapy. Rectal Neoplasms / radiotherapy

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  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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68. Braun KP, Braun V, Brookman-Amissah S, May M, Ptok H, Lippert H, Gastinger I: [Treatment of rectal carcinoma: satisfaction of general practitioners with surgical clinics]. Chirurg; 2009 Dec;80(12):1147-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment of rectal carcinoma: satisfaction of general practitioners with surgical clinics].
  • The study group (SG) comprised 265 patients with rectal carcinoma, who were treated by 204 general practitioners and in 17 different hospitals.
  • The surgical expertise regarding the treatment of rectal carcinoma was assessed as the main quality parameter of the hospital.
  • [MeSH-major] Attitude of Health Personnel. Family Practice. Rectal Neoplasms / surgery. Referral and Consultation. Surgery Department, Hospital

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  • [CommentIn] Chirurg. 2009 Dec;80(12):1152 [19997792.001]
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  • [ISSN] 1433-0385
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Multicenter Study
  • [Publication-country] Germany
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69. Burghofer K, Lackner CK, Jauch KW: [Empathy in surgery. Awareness of the quality of life in patients with rectal carcinoma]. Chirurg; 2007 Jun;78(6):552, 554-8, 560
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Empathy in surgery. Awareness of the quality of life in patients with rectal carcinoma].
  • In this study the empathy of surgeons was evaluated by asking them to put themselves in the preoperative situation of a patient with a rectal carcinoma.
  • The data collected from the surgeons were compared with the results of a prospective longitudinal analysis of the quality of life of rectal carcinoma patients.
  • [MeSH-major] Empathy. General Surgery. Physician-Patient Relations. Quality of Life. Rectal Neoplasms / psychology

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  • (PMID = 17588184.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Germany
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70. Uehara K, Yamamoto S, Fujita S, Akasu T, Moriya Y: Impact of upward lymph node dissection on survival rates in advanced lower rectal carcinoma. Dig Surg; 2007;24(5):375-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of upward lymph node dissection on survival rates in advanced lower rectal carcinoma.
  • BACKGROUND/AIMS: This study investigated appropriate level of upward lymph node (LN) dissection in advanced lower rectal carcinoma.
  • METHODS: A total of 285 consecutive patients with stage II/III lower rectal carcinoma were analyzed.
  • LN dissection was classified as follows: division of the root of the superior rectal artery (UD2), division of the root of the inferior mesenteric artery (UD3) and UD3 with para-aortic LN dissection (UD4).
  • On the other hand, LN metastases along the superior rectal artery were discovered in 14 patients, whose 5-year overall survival rate was 61.2%.
  • By removing the LNs either UD2 or UD3/4, a similar survival rate was achieved in stage III patients with LN metastases along the superior rectal artery.
  • Additionally, survival is no worse in patients with positive LN along the superior rectal artery as long as these positive nodes are resected by either UD2 or UD3/4.
  • Low ligation is adequate for advanced lower rectal carcinoma.
  • [MeSH-major] Carcinoma / surgery. Lymph Node Excision. Rectal Neoplasms / surgery
  • [MeSH-minor] Female. Follow-Up Studies. Humans. Japan. Kaplan-Meier Estimate. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Survival Rate. Time Factors

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  • (PMID = 17785983.001).
  • [ISSN] 0253-4886
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Switzerland
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71. Braat AE, Oosterhuis JW, Moll FC, de Vries JE, Wiggers T: Sentinel node detection after preoperative short-course radiotherapy in rectal carcinoma is not reliable. Br J Surg; 2005 Dec;92(12):1533-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sentinel node detection after preoperative short-course radiotherapy in rectal carcinoma is not reliable.
  • BACKGROUND: Sentinel node (SN) detection may be used in patients with colonic carcinoma.
  • However, its use in patients with rectal carcinoma may be unreliable.
  • To address this, SN detection was evaluated in patients with rectal carcinoma after short-course preoperative radiotherapy.
  • In addition, SN detection was performed in 57 patients with colonic carcinoma.
  • RESULTS: A SN was identified in 26 of 34 patients with rectal carcinoma.
  • By contrast, SN detection was possible in 56 of 57 patient with colonic carcinoma with a sensitivity of 90 per cent, and four patients were upstaged.
  • CONCLUSION: The SN procedure for rectal carcinoma is not reliable in combination with TME and preoperative short-course radiotherapy.
  • [MeSH-major] Colonic Neoplasms / pathology. Rectal Neoplasms / pathology

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  • [Copyright] Copyright (c) 2005 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
  • (PMID = 16231281.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / Rosaniline Dyes; 129-17-9 / patent blue violet
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72. Yang X, Li LR, Pan ZZ, Zhou ZW, Wan DS: [Lymphatic vessel density in Dukes' B rectal carcinoma and its correlation to prognosis]. Ai Zheng; 2006 Jun;25(6):749-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Lymphatic vessel density in Dukes' B rectal carcinoma and its correlation to prognosis].
  • BACKGROUND & OBJECTIVE: The prognosis of patients diagnosed with Dukes' B rectal carcinoma varies largely.
  • Micrometastasis via lymphatic vessel may have occurred in Dukes' B rectal carcinoma although no clinical pathologic evidence of lymph node metastasis was found.
  • This study was to investigate the correlation of lymphatic vessel density (LVD) to the prognosis of Dukes' B rectal carcinoma.
  • METHODS: Immunohistochemistry was used to display the lymphatic vessels with lymphatic endothelium-specific marker, lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), in 54 specimens from Dukes' B rectal carcinoma.
  • LVD may not be a prognostic factor of Dukes' B rectal carcinoma.
  • [MeSH-major] Lymphatic Vessels / pathology. Rectal Neoplasms / pathology. Vesicular Transport Proteins / metabolism
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Immunohistochemistry. Lymphangiogenesis. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Prognosis. Rectum / metabolism. Rectum / pathology. Survival Rate

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  • (PMID = 16764774.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / LYVE1 protein, human; 0 / Vesicular Transport Proteins
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73. Wu ZY, Wan J, Li JH, Zhao G, Peng L, Yao Y, Du JL, Liu QF, Wang ZD, Huang ZM, Lin HH: Study of circumferential resection margin in patients with middle and lower rectal carcinoma. World J Gastroenterol; 2007 Jun 28;13(24):3380-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Study of circumferential resection margin in patients with middle and lower rectal carcinoma.
  • AIM: To clarify the relationship between circumferential resection margin status and local and distant recurrence as well as survival of patients with middle and lower rectal carcinoma.
  • The relationship between circumferential resection margin status and clinicopathologic characteristics of middle and lower rectal carcinoma was also evaluated.
  • METHODS: Cancer specimens from 56 patients with middle and lower rectal carcinoma who received total mesorectal excision at the Department of General Surgery of Guangdong Provincial People's Hospital were studied.
  • RESULTS: Local recurrence occurred in 12.5% (7 of 56 cases) of patients with middle and lower rectal carcinoma.
  • Distant recurrence occurred in 25% (14 of 56 cases) of patients with middle and lower rectal carcinoma.
  • In 18 cancer specimens with tumor diameter >= 5 cm 7 (38.9%) were detected as positive circumferential resection margin, while in 38 cancer specimens with a tumor diameter of < 5 cm only 5 (13.2%) were positive for circumferential resection margin (P = 0.028).
  • The circumferential resection margin status is an important predictor of local and distant recurrence as well as survival of patients with middle and lower rectal carcinoma.
  • [MeSH-major] Rectal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local

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  • (PMID = 17659680.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4172721
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74. Zheng BA, Zou SC, Deng GL, Tu SL, Chen YW, Xu HY, Dong QJ: [Surgical treatment for local recurrence of rectal carcinoma after operation]. Zhonghua Wei Chang Wai Ke Za Zhi; 2007 Nov;10(6):543-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment for local recurrence of rectal carcinoma after operation].
  • OBJECTIVE: To evaluate the value of reoperation for local recurrence of rectal carcinoma.
  • METHODS: The data of 62 cases with post-operative local recurrence of rectal carcinoma were analyzed retrospectively.
  • CONCLUSIONS: The recurrence of rectal carcinoma still needs positive operation in order to prolong the survival time and improve the quality of life of the patient.
  • [MeSH-major] Neoplasm Recurrence, Local / surgery. Rectal Neoplasms / pathology. Rectal Neoplasms / surgery. Reoperation

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  • (PMID = 18000776.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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75. Matsuoka H, Nakamura A, Masaki T, Sugiyama M, Nitatori T, Ohkura Y, Sakamoto A, Atomi Y: Optimal diagnostic criteria for lateral pelvic lymph node metastasis in rectal carcinoma. Anticancer Res; 2007 Sep-Oct;27(5B):3529-33

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optimal diagnostic criteria for lateral pelvic lymph node metastasis in rectal carcinoma.
  • AIM: The purpose of this study was to determine the optimal diagnostic criteria for lateral pelvic lymph node metastasis in patients with rectal carcinoma.
  • PATIENTS AND METHODS: From July 1997 to June 2005, fifty-one patients with locally advanced middle or lower rectal carcinoma underwent preoperative MRI examination, followed by total mesorectal excision with lateral pelvic node dissection.
  • CONCLUSION: An ovoid shape with a transverse axis diameter of 5 mm or larger on MRI was considered as the optimal criterion for diagnosing lateral lymph node metastasis in patients with rectal carcinoma.
  • [MeSH-major] Lymph Nodes / pathology. Pelvic Neoplasms / pathology. Rectal Neoplasms / diagnosis. Rectal Neoplasms / secondary

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  • (PMID = 17972513.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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76. Vogl TJ, Pegios W, Bechstein WO, Floeter J: [Radiological diagnostics and follow-up of rectal carcinoma]. Rofo; 2006 Oct;178(10):970-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Radiological diagnostics and follow-up of rectal carcinoma].
  • Rectal carcinoma is one of the most frequent malignant tumors in adulthood.
  • Not only after total resection but also after partial resection of the tumor with postoperative radiochemotherapy a sufficient follow-up is necessary to diagnose recurrent rectal cancer as early as possible.
  • In addition to routine examinations, the physician can choose between CT, MRI, endosonography and functional imaging techniques such as PET and immunoscintigraphy for further evaluation if a recurrent rectal cancer is suspected.
  • In addition to the detection of small nodular pulmonary metastases, MRI with its "phased-array" coils is another excellent tool for the diagnosis of recurrent rectal cancer and search for metastases.
  • This review shows the advantages and disadvantages of each diagnostic method in the visualization of recurrent rectal cancer.
  • [MeSH-major] Magnetic Resonance Imaging / trends. Positron-Emission Tomography / trends. Rectal Neoplasms / diagnosis. Tomography, X-Ray Computed / trends

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  • (PMID = 17021976.001).
  • [ISSN] 1438-9029
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 38
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77. Yamamoto S, Yoshimura K, Konishi F, Watanabe M: Phase II trial to evaluate laparoscopic surgery for Stage 0/I rectal carcinoma. Jpn J Clin Oncol; 2008 Jul;38(7):497-500
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase II trial to evaluate laparoscopic surgery for Stage 0/I rectal carcinoma.
  • Recently reported randomized controlled trials demonstrated that laparoscopic surgery (LS) was comparable or superior to open surgery with regard to the long-term outcome for colon and rectosigmoidal carcinoma; however, controversy persists with regard to the appropriateness of LS for patients with rectal carcinoma.
  • To examine the technical and oncological feasibility of LS for rectal carcinoma, a phase II trial was started in patients with a preoperative diagnosis of Stage 0/I rectal carcinoma, under the direction of the Japan Society of Laparoscopic Colorectal Surgery.
  • [MeSH-major] Adenocarcinoma / surgery. Laparoscopy. Rectal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Clinical Protocols. Feasibility Studies. Humans. Japan. Middle Aged. Neoplasm Staging. Patient Selection. Research Design

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  • (PMID = 18586667.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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78. Yan SL, Xu ZB, Chi P, Lin HM: [Comparing the influencing factors of anastomotic bleeding in rectal carcinoma resection between laparoscopic and open radical approaches]. Zhonghua Wei Chang Wai Ke Za Zhi; 2007 Mar;10(2):157-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Comparing the influencing factors of anastomotic bleeding in rectal carcinoma resection between laparoscopic and open radical approaches].
  • OBJECTIVE: To observe the occurrence of anastomotic bleeding following laparoscopic and open radical resection for rectal carcinoma, and to explore its contributing factors.
  • METHODS: Two hundred and sixty-three cases of rectal carcinoma undergone radical resection were divided into 2 groups, laparoscopic surgery (LS) group (n=86) and open surgery (OS) group (n=177).
  • RESULTS: Anastomotic bleeding occurred on 16 out of 263 patients with radical resection of rectal cancer (6.1%).
  • [MeSH-major] Anastomosis, Surgical / adverse effects. Laparoscopy / adverse effects. Postoperative Hemorrhage / etiology. Rectal Neoplasms / surgery

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  • (PMID = 17380458.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] China
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79. Ha SS, Choi HJ, Park KJ, Kim JM, Kim SH, Roh YH, Kwon HC, Roh MS: Intensity of tumor budding as an index for the malignant potential in invasive rectal carcinoma. Cancer Res Treat; 2005 Jun;37(3):177-82

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intensity of tumor budding as an index for the malignant potential in invasive rectal carcinoma.
  • PURPOSE: The aim of this study was to quantitatively assess the intensity of tumor budding in rectal carcinoma and to determine how it correlates with the malignant potential.
  • MATERIALS AND METHODS: Intensities of the tumor budding at the invasive front of the surgical specimens from 90 patients (male, 51) with well- or moderately-differentiated rectal carcinoma were investigated.
  • CONCLUSION: Tumor budding at the invasive margin is a reliable pathologic index that indicates a higher malignant potential and a less favorable prognosis for patients with advanced rectal carcinoma.

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  • (PMID = 19956500.001).
  • [ISSN] 2005-9256
  • [Journal-full-title] Cancer research and treatment : official journal of Korean Cancer Association
  • [ISO-abbreviation] Cancer Res Treat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2785407
  • [Keywords] NOTNLM ; Malignant potential / Rectal carcinoma / Tumor budding
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80. Liu Z, Wang XD, Li L: [Perioperative fast track programs enhance the postoperative recovery after rectal carcinoma resection]. Zhonghua Wei Chang Wai Ke Za Zhi; 2008 Nov;11(6):551-3
MedlinePlus Health Information. consumer health - Rehabilitation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Perioperative fast track programs enhance the postoperative recovery after rectal carcinoma resection].
  • OBJECTIVE: To evaluate the effect of the fast track programs (FT) on the postoperative recovery of patients with rectum carcinoma after rectal cancer resection.
  • METHODS: Eighty-three patients, undergone elective rectal carcinoma resection in our hospital, were randomly divided into two groups.
  • CONCLUSION: The colorectal surgical fast track programs applied to the perioperative period care of rectal carcinoma resection can decrease the hospital stay and surgical complications with no obvious change in readmission rate, so the postoperative recovery of patients with rectal carcinoma resection can be improved.
  • [MeSH-major] Colorectal Surgery / rehabilitation. Perioperative Care. Rectal Neoplasms / rehabilitation. Rehabilitation / methods

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  • (PMID = 19031133.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] China
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81. Hoerske C, Weber K, Goehl J, Hohenberger W, Merkel S: Long-term outcomes and quality of life after rectal carcinoma surgery. Br J Surg; 2010 Aug;97(8):1295-303

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term outcomes and quality of life after rectal carcinoma surgery.
  • BACKGROUND: A cohort study was undertaken to investigate the long-term oncological outcome, late adverse effects and quality of life (QOL) after treatment for rectal cancer.
  • METHODS: This was an analysis of prospectively collected data from 268 consecutive patients with rectal carcinoma treated between 1995 and 1997 at the Department of Surgery, University Hospital Erlangen, Germany.
  • Analysis of QOL in 97 long-term survivors showed that receiving chemoradiotherapy, a permanent stoma and lower-third rectal carcinoma were associated with significantly worse outcomes on several measures.
  • [MeSH-major] Quality of Life. Rectal Neoplasms / surgery

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  • [Copyright] Copyright (c) 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
  • (PMID = 20602501.001).
  • [ISSN] 1365-2168
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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82. Chen KY, Xiang GA, Wang HN, Xiao FL: [Simultaneous laparoscopic excision for the treatment of rectal carcinoma and the synchronous hepatic metastasis]. Zhonghua Zhong Liu Za Zhi; 2009 Jan;31(1):69-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Simultaneous laparoscopic excision for the treatment of rectal carcinoma and the synchronous hepatic metastasis].
  • OBJECTIVE: To evaluate the therapeutic efficacy of simultaneous laparoscopic excision for the treatment of rectal carcinoma and synchronous hepatic metastasis.
  • METHODS: Totally 38 patients with rectal carcinoma and synchronous hepatic metastasis detected by CT scan were included in this study.
  • Among them, 23 patients in the group A were treated with laparoscopic surgery, and the other 18 patients in the group B with traditional abdominal operation to resect the rectal tumor and hepatic metastasis simultaneously.
  • CONCLUSION: Simultaneous laparoscopic excision of rectal carcinoma and synchronous hepatic metastasis is safe, effective and minimally invasive with a similar survival achieved by traditional open abdominal operation.
  • [MeSH-major] Adenocarcinoma / surgery. Laparoscopy / methods. Liver Neoplasms / surgery. Rectal Neoplasms / surgery

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  • (PMID = 19538876.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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83. Topkan E, Karaoglu A: Octreotide in the management of chemoradiotherapy-induced diarrhea refractory to loperamide in patients with rectal carcinoma. Oncology; 2006;71(5-6):354-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Octreotide in the management of chemoradiotherapy-induced diarrhea refractory to loperamide in patients with rectal carcinoma.
  • METHODS: Forty-two rectal carcinoma (T(3-4)N(0-2)M(0)) patients with grade 2 or 3 diarrhea refractory to loperamide were enrolled to receive octreotide.
  • [MeSH-major] Carcinoma / drug therapy. Carcinoma / radiotherapy. Diarrhea / drug therapy. Loperamide / therapeutic use. Octreotide / therapeutic use. Rectal Neoplasms / drug therapy. Rectal Neoplasms / radiotherapy

  • Genetic Alliance. consumer health - Diarrhea.
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  • [Copyright] Copyright 2006 S. Karger AG, Basel.
  • (PMID = 17873499.001).
  • [ISSN] 1423-0232
  • [Journal-full-title] Oncology
  • [ISO-abbreviation] Oncology
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 6X9OC3H4II / Loperamide; RWM8CCW8GP / Octreotide; U3P01618RT / Fluorouracil
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84. Akasu T, Yamaguchi T, Fujimoto Y, Ishiguro S, Yamamoto S, Fujita S, Moriya Y: Abdominal sacral resection for posterior pelvic recurrence of rectal carcinoma: analyses of prognostic factors and recurrence patterns. Ann Surg Oncol; 2007 Jan;14(1):74-83

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abdominal sacral resection for posterior pelvic recurrence of rectal carcinoma: analyses of prognostic factors and recurrence patterns.
  • BACKGROUND: Local recurrence of rectal cancer presents challenging problems.
  • The purpose of this study was to evaluate the results of ASR for posterior pelvic recurrence of rectal carcinoma and to analyze prognostic factors and recurrence patterns.
  • [MeSH-major] Pelvic Neoplasms / secondary. Pelvic Neoplasms / surgery. Rectal Neoplasms / pathology. Sacrum / surgery. Spinal Neoplasms / secondary. Spinal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Disease-Free Survival. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Pelvic Exenteration. Postoperative Complications. Prognosis. Survival Rate

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  • (PMID = 17061173.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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85. Rahman GA, Braimoh KT: Preoperative staging of rectal carcinoma using transrectal ultrasonography (Trus): experience with 30 Nigerians. Niger Postgrad Med J; 2007 Sep;14(3):226-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative staging of rectal carcinoma using transrectal ultrasonography (Trus): experience with 30 Nigerians.
  • BACKGROUND AND OBJECTIVE: Colorectal cancer is the second most common malignancy; accounting for approximately 155,000 new diagnosed cases each year in the United States.
  • For cancers specifically located in the rectum, various therapeutic options are available including local excision, total mesorectal excision, preoperative radiotherapy etc.
  • The choice of surgery as well as possible outcome largely depends on the depth of tumour infiltration of the rectal wall as well as extent of perirectal tissue involvement.
  • The aim of this study was to assess local fixity clinically and also to assess the ability of transrectal ultrasound (TRUS) to fulfil staging requirements in patients with rectal cancer.
  • MATERIALS AND METHODS: Thirty consecutive patients with histologically confirmed rectal carcinoma at UITH, Ilorin from January 1998 to December 2002 who underwent preoperative TRUS were prospectively studied.
  • After clinical examination including digital rectal examination they all had TRUS, proctoscopy and sigmoidoscopy.
  • Digital Rectal Examination (DRE) identified four patients with peri-rectal lymph nodes but TRUS picked six; though only five were histologically positive.
  • [MeSH-major] Adenocarcinoma / pathology. Rectal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Neoplasm Staging. Nigeria

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  • (PMID = 17767208.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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86. Cathomas R, Geldart TR, Iveson T, Singh N, Rowen D: An unusual differential diagnosis of penile warts: metastases from rectal carcinoma. Int J STD AIDS; 2006 Jul;17(7):491-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An unusual differential diagnosis of penile warts: metastases from rectal carcinoma.
  • Their diagnosis is usually based on clinical observation and biopsy is not generally undertaken.
  • We report the case of a patient presenting with penile metastases from rectal carcinoma arising during third-line chemotherapy for metastatic disease.
  • [MeSH-major] Adenocarcinoma / secondary. Penile Neoplasms / secondary. Penis / pathology. Rectal Neoplasms / pathology. Warts / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Penile Diseases / diagnosis. Penile Diseases / pathology

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  • (PMID = 16820084.001).
  • [ISSN] 0956-4624
  • [Journal-full-title] International journal of STD & AIDS
  • [ISO-abbreviation] Int J STD AIDS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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87. Yildirim M, Coskun A, Pürten M, Oztekin O, Ilhan E: A clinical case of the penile metastasis from the rectal carcinoma. Radiol Oncol; 2010 Jun;44(2):121-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A clinical case of the penile metastasis from the rectal carcinoma.
  • BACKGROUND: Penile metastases are rare and usually secondary to genitourinary and colorectal cancer.
  • CASE REPORT: We present a case of a 77-year-old man with penile metastasis who was operated for rectal carcinoma.
  • CONCLUSIONS: Imaging methods and biopsy may help to clarify the diagnosis but the treatment modalities are insufficient in these patients.

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  • (PMID = 22933902.001).
  • [ISSN] 1318-2099
  • [Journal-full-title] Radiology and oncology
  • [ISO-abbreviation] Radiol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Slovenia
  • [Other-IDs] NLM/ PMC3423681
  • [Keywords] NOTNLM ; carcinoma / metastasis / penis / rectum
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88. Kube R, Ptok H, Jacob D, Fahlke J, Mroczkowski P, Lippert H, Ziegenhardt G, Schmidt U, Gastinger I: Modified neoadjuvant short-course radiation therapy in uT3 rectal carcinoma: low local recurrence rate with unchanged overall survival and frequent morbidity. Int J Colorectal Dis; 2010 Jan;25(1):109-17

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Modified neoadjuvant short-course radiation therapy in uT3 rectal carcinoma: low local recurrence rate with unchanged overall survival and frequent morbidity.
  • PURPOSE: The purpose of this study is to investigate the value of a modified neoadjuvant short-course radiation therapy (SCRT) in uT3 rectal carcinoma, which, despite local R0 resectability, carries a greater risk of local recurrence than less invasive carcinomas.
  • METHODS: Sixty-three patients with uT3 rectal carcinoma < or =10 cm above the anal verge received a modified 8 x 3 Gy pre-operative SCRT.
  • CONCLUSIONS: Compared to the literature-modified 8 x 3 Gy neoadjuvant SCRT and surgery in uT3, rectal carcinoma was associated with low local recurrence but frequent peri-operative complications.
  • [MeSH-major] Neoadjuvant Therapy. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / pathology. Rectal Neoplasms / epidemiology. Rectal Neoplasms / radiotherapy
  • [MeSH-minor] Aged. Dose-Response Relationship, Radiation. Female. Follow-Up Studies. Germany / epidemiology. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Staging. Postoperative Care. Postoperative Complications / etiology. Radiotherapy, Adjuvant / adverse effects. Survival Analysis. Time Factors

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  • [CommentIn] Int J Colorectal Dis. 2010 Feb;25(2):285-7 [19859720.001]
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  • (PMID = 19876634.001).
  • [ISSN] 1432-1262
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
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89. Nehls O, Okech T, Hsieh CJ, Sarbia M, Borchard F, Gruenagel HH, Gaco V, Porschen R, Gregor M, Klump B: Low BAX protein expression correlates with disease recurrence in preoperatively irradiated rectal carcinoma. Int J Radiat Oncol Biol Phys; 2005 Jan 1;61(1):85-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low BAX protein expression correlates with disease recurrence in preoperatively irradiated rectal carcinoma.
  • PURPOSE: To determine the prognostic impact of BAX in correlation to its upstream effector p53 as well as clinicopathologic variables and patient outcome in preoperatively irradiated rectal carcinoma.
  • METHODS AND MATERIALS: We investigated 92 rectal carcinoma patients treated by preoperative radiotherapy to a total dose of 30 Gy followed by surgery.
  • CONCLUSIONS: This study demonstrates that BAX protein expression might help to predict disease recurrence in preoperatively irradiated rectal carcinoma, whereas determination of p53, the proposed upstream regulator of BAX-induced apoptosis, did not provide additional prognostic information.
  • [MeSH-major] Adenocarcinoma / chemistry. Proto-Oncogene Proteins c-bcl-2 / analysis. Rectal Neoplasms / chemistry
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Apoptosis. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Statistics as Topic. Tumor Suppressor Protein p53 / analysis. bcl-2-Associated X Protein

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  • (PMID = 15629598.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / BAX protein, human; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Tumor Suppressor Protein p53; 0 / bcl-2-Associated X Protein
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90. Wang H, Fu CG, Zheng JM, Gong HF, Tao LY, Yu ED, Zhang W, Liu LJ, Hao LQ, Meng RG: [Impact of meticulousness of pathologists on lymph node harvest after radical resection of invasive rectal carcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2009 Nov;12(6):569-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Impact of meticulousness of pathologists on lymph node harvest after radical resection of invasive rectal carcinoma].
  • OBJECTIVE: To analyze the impact of meticulousness of pathologists on the lymph node harvest after radical resection of invasive rectal carcinoma.
  • METHODS: From January 2008 to May 2009, the clinical data of rectal cancer patients undergone operation were reviewed retrospectively.
  • After multidisciplinary cooperation on rectal cancer, a new rule was applied to request the pathologists to find no less than 15 nodes in single colorectal specimen from January 2009.
  • Excluded criteria were recurrent colorectal tumor, Tis tumor, R(1) or R(2) resection, tumor resection transanally or endoscopically, the cases enrolled in other prospective research, synchronous diseases affecting the surgical procedure for the rectal cancer (familial adenomatous polyposis, synchronous colorectal carcinoma) and rectal cancer receiving neoadjuvant chemoradiation.
  • The good performance of pathologists could produce adequate number of lymph nodes for rectal cancer without neoadjuvant chemoradiation.
  • [MeSH-major] Biopsy. Lymph Node Excision. Lymph Nodes / pathology. Rectal Neoplasms / pathology
  • [MeSH-minor] Female. Humans. Male. Middle Aged. Neoplasm Staging. Postoperative Period. Rectum / pathology. Retrospective Studies

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  • (PMID = 19921565.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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91. Masljankov S, Jaramov N: [Analysis of oncologic results and quality of life after radical treatment of rectum carcinoma in Specialized Oncological Hospital of Veliko Tarnovo]. Khirurgiia (Sofiia); 2009;(4-5):10-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of oncologic results and quality of life after radical treatment of rectum carcinoma in Specialized Oncological Hospital of Veliko Tarnovo].
  • INTRODUCTION: Rectum carcinoma is an increasing problem with a great variety of possible operative decisions.
  • The aim of this study is to present and analyze the oncologic and initial quality of life data of operated with rectum carcinoma in Specialized Oncological Hospital of Veliko Tarnovo.
  • CONCLUSION: We have better onologic and functional result in early stages and at higher localization of rectum carcinoma disease.
  • [MeSH-major] Carcinoma / surgery. Quality of Life. Rectal Neoplasms / surgery

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  • (PMID = 20506798.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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92. Kocakova I, Svoboda M, Kubosova K, Chrenko V, Roubalova E, Krejci E, Sefr R, Slampa P, Frgala T, Zaloudik J: Preoperative radiotherapy and concomitant capecitabine treatment induce thymidylate synthase and thymidine phosphorylase mRNAs in rectal carcinoma. Neoplasma; 2007;54(5):447-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative radiotherapy and concomitant capecitabine treatment induce thymidylate synthase and thymidine phosphorylase mRNAs in rectal carcinoma.
  • This work is intended to study the effect of preoperative capecitabine and radiotherapy treatment on the levels of thymidylate synthase (TS), thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) mRNAs in rectal carcinoma.
  • 55 patients with locally advanced rectal carcinoma (cT3-4, N0, M0 or cT2-4,N+, M0) were treated with capecitabine 825 mg/m2 twice a day and pelvic radiotherapy 1,8 Gy daily up to cumulative dose of 45 Gy, boosting up to 50,4 Gy.
  • Biopsies of rectal carcinoma were taken before starting therapy and 14 days after its cesation.
  • [MeSH-major] Antimetabolites, Antineoplastic / therapeutic use. Deoxycytidine / analogs & derivatives. Fluorouracil / analogs & derivatives. RNA, Messenger / genetics. Rectal Neoplasms / genetics. Rectal Neoplasms / radiotherapy. Thymidine Phosphorylase / genetics. Thymidylate Synthase / genetics
  • [MeSH-minor] Adult. Aged. Capecitabine. Carcinoembryonic Antigen / blood. Combined Modality Therapy. Genetic Markers. Humans. Middle Aged. Neoplasm Staging. Polymerase Chain Reaction. Pyrimidines / metabolism

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  • (PMID = 17688376.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Carcinoembryonic Antigen; 0 / Genetic Markers; 0 / Pyrimidines; 0 / RNA, Messenger; 0W860991D6 / Deoxycytidine; 6804DJ8Z9U / Capecitabine; EC 2.1.1.45 / Thymidylate Synthase; EC 2.4.2.4 / Thymidine Phosphorylase; K8CXK5Q32L / pyrimidine; U3P01618RT / Fluorouracil
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93. Choi HJ, Park KJ, Shin JS, Roh MS, Kwon HC, Lee HS: Tumor budding as a prognostic marker in stage-III rectal carcinoma. Int J Colorectal Dis; 2007 Aug;22(8):863-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumor budding as a prognostic marker in stage-III rectal carcinoma.
  • BACKGROUND AND AIM: Tumor budding along the invasive margin is known to be associated with biological behavior in colorectal carcinoma.
  • The aims of this study were to explore if the semiquantitative assessment of tumor budding in rectal cancers correlates with oncological behavior and to appraise if the tumor budding is valid as a pathological parameter in distinguishing tumors with higher malignancy potential from those with lower one for prognostic stratification.
  • MATERIALS AND METHODS: Surgical specimens from 244 patients with well- or moderately differentiated rectal carcinoma were retrieved to assess the intensity of tumor budding at the invasive margin.
  • When scores were given to grade of budding (lower, 0; higher, 1) and N stage (N1, 0; N2, 1) in stage III, a better prognostic stratification in terms of the 5-year DFS was obtained than the American Joint Committee on Cancer nodal staging only (0 vs 1 vs 2, 66.5 vs 42.6 vs 29.2%; p = 0.0101).
  • Scoring system using tumor budding and N stage showed better prognostic stratification in stage-III rectal carcinoma.
  • [MeSH-major] Rectal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cell Differentiation. Disease-Free Survival. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Predictive Value of Tests. Prognosis. Reproducibility of Results. Retrospective Studies. Time Factors

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  • (PMID = 17216219.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Germany
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94. Merkel S, Hohenberger W, Hermanek P: [Intra-operative local tumor cell dissemination in rectal carcinoma surgery: effect of operation principles and neoadjuvant therapy]. Chirurg; 2010 Aug;81(8):719-27

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intra-operative local tumor cell dissemination in rectal carcinoma surgery: effect of operation principles and neoadjuvant therapy].
  • BACKGROUND: The influence of surgical principles and neoadjuvant therapy on the frequency of local tumor cell dissemination (LTCD) in rectal carcinoma surgery and its consequences for local recurrence and survival rates were analyzed.
  • [MeSH-major] Neoadjuvant Therapy. Neoplasm Seeding. Rectal Neoplasms / pathology. Rectal Neoplasms / surgery
  • [MeSH-minor] Humans. Neoplasm Invasiveness. Neoplasm Recurrence, Local / etiology. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / radiotherapy. Prognosis. Quality Assurance, Health Care. Radiotherapy, Adjuvant. Rectum / pathology. Rectum / surgery. Registries. Survival Rate

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  • (PMID = 20694787.001).
  • [ISSN] 1433-0385
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
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95. Debnath CR, Debnath MR, Gafur MA, Huq MH: A 12 years old boy with carcinoma rectum. Mymensingh Med J; 2010 Jan;19(1):116-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A 12 years old boy with carcinoma rectum.
  • Primary gastrointestinal malignancy constitutes approximately 2% of pediatric neoplasm and colorectal carcinoma is the second most common malignancy among them.
  • Carcinoma of the rectum must be considered as a differential diagnosis in childhood if patient presents with per rectal bleeding in conjunction with abdominal pain & weight loss.
  • In our article a 12 years old boy with Mucin secreting adenocarcinoma is being presented.
  • Later on, by simple digital rectal examination (DRE) he was clinically diagnosed as a case of CA Rectum and eventually, the diagnosis was established by colonoscopy followed by biopsy.

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  • (PMID = 20046183.001).
  • [ISSN] 1022-4742
  • [Journal-full-title] Mymensingh medical journal : MMJ
  • [ISO-abbreviation] Mymensingh Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Bangladesh
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96. He W, Deng HJ, Yu J, Zhang C, Wang YN, Cheng X, Li GX: [Effect of laparoscopic-assisted resection of rectal carcinoma on C-reactive protein and humoral immunity]. Zhonghua Wei Chang Wai Ke Za Zhi; 2009 Jul;12(4):357-60
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effect of laparoscopic-assisted resection of rectal carcinoma on C-reactive protein and humoral immunity].
  • OBJECTIVE: To investigate the effect of laparoscopic-assisted resection of rectal carcinoma on perioperative levels of C-reactive protein (CRP), immunoglobulins(Ig) and complements.
  • METHODS: Fifty-four patients with rectal carcinoma were divided into laparoscopic group (n=26) and open operation group(n=28) according to the patients' will.
  • CONCLUSION: Laparoscopic-assisted resection of rectal carcinoma results in less wound, lower levels of stress response, and less effect on immune function compared to open surgery, which recovers the immune function of patients more rapidly after operation.
  • [MeSH-major] C-Reactive Protein / metabolism. Immunity, Humoral. Rectal Neoplasms / blood. Rectal Neoplasms / immunology

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  • (PMID = 19598018.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 9007-41-4 / C-Reactive Protein
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97. Hu K, Wang B, Li P, Wang K, Zhang W, Guo ZY, Xu G, Dong DD, Zhu H: [Clinicopathologic study of distal 2 cm rectal carcinoma intramural spread over dentate line]. Zhonghua Wei Chang Wai Ke Za Zhi; 2008 Jan;11(1):44-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinicopathologic study of distal 2 cm rectal carcinoma intramural spread over dentate line].
  • OBJECTIVE: To study the extent of distal intramural spread of distal 2 cm rectal carcinoma over the dentate line, and to improve quality of life for these patients through providing pathological evidence of operation mode choice.
  • METHODS: Specimens of thirty patients with rectal carcinoma, operated with ISR(intersphincter resection) or Miles procedure from May 2005 to July 2007, were collected, and their large and histology pathologic slices were examined.
  • The length of distal intramural spread to rectal carcinoma was measured under light microscope.
  • CONCLUSION: Distal 2 cm rectal carcinomas seldom spread over dentate lines.
  • [MeSH-major] Rectal Neoplasms / pathology
  • [MeSH-minor] Aged. Female. Humans. Male. Middle Aged. Neoplasm Staging. Quality of Life

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  • (PMID = 18197493.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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98. Ayadi L, Zribi J, Mziou TJ, Ellouz S, Khabir A, Bahri I, Turki H, Sellami-Boudawara T: [Scalp metastasis from small cell carcinoma of the rectum: an unusual case]. Tunis Med; 2009 May;87(5):354-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Scalp metastasis from small cell carcinoma of the rectum: an unusual case].
  • [Transliterated title] Métastase au niveau du cuir chevelu d'un carcinome a petites cellules du rectum: un cas inhabituel.
  • BACKGROUND: Cutaneous metastasis of rectal carcinoma is a rare event.
  • It occurs in 4% of all patients with rectal cancer.
  • Skin metastasis of rectal cancer are usually detected near the initial tumor, especially in the periumbilical region; but they rarely occur in the scalp.
  • AIM: To report a new case of scalp metastases from rectal tumor.
  • CASE REPORT: Our patient was a 63-year old male with a history of small cell carcinoma of the rectum who subsequently developed a single nodule of the scalp of 4cm.
  • Histopathological analysis revealed a small cell carcinoma infiltrating the dermis and subcutaneous tissue.
  • CONCLUSION: In contrast to the prior cases of scalp metastases reported in the literature, ours is the first documentation of such an occurrence from rectal small cell carcinoma.
  • The early diagnosis of skin metastases in these patients is very important because it can alter treatment.
  • [MeSH-major] Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / secondary. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / secondary. Rectal Neoplasms / pathology. Scalp. Skin Neoplasms / diagnosis. Skin Neoplasms / secondary

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  • (PMID = 19927770.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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99. Sameer AS, Syeed N, Chowdri NA, Parray FQ, Siddiqi MA: Squamous cell carcinoma of rectum presenting in a man: a case report. J Med Case Rep; 2010;4:392

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Squamous cell carcinoma of rectum presenting in a man: a case report.
  • Until now, to the best of our knowledge, only 114 cases of squamous cell carcinoma in the colorectum exist in the reported literature.
  • Here we report a case of squamous cell carcinoma of the rectum in the ethnic Kashmiri population in northern India.
  • CASE PRESENTATION: The case of a 60-year-old male patient (Asian) with a pure squamous cell carcinoma of the rectum is presented here.
  • CONCLUSION: The prognosis for squamous cell carcinoma of the colorectum is worse than for that of adenocarcinoma, because of the delayed diagnosis.
  • The etiopathogenicity of squamous cell carcinoma of the colorectum is discussed.

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  • (PMID = 21118539.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3014960
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100. Rullier A, Laurent C, Vendrely V, Le Bail B, Bioulac-Sage P, Rullier E: Impact of colloid response on survival after preoperative radiotherapy in locally advanced rectal carcinoma. Am J Surg Pathol; 2005 May;29(5):602-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of colloid response on survival after preoperative radiotherapy in locally advanced rectal carcinoma.
  • Neoadjuvant therapy for rectal carcinoma modifies morphology and natural history of the tumor.
  • This study evaluated influence of tumor histologic response, especially of colloid response, on survival in patients treated by long-course preoperative radiotherapy for rectal cancer.
  • In 200 patients with uT3-T4 or N1 rectal carcinomas, influence of type of surgery, dose of radiotherapy, residual tumor size, surface tumor aspect, tumor response (downstaging vs. colloid or no response), tumor grade, vascular and neural invasion, circumferential margin, and postoperative chemotherapy on 5-year overall and disease-free survival were studied by univariate and multivariate analyses.
  • After preoperative radiotherapy for rectal cancer, survival and type of recurrence are influenced by the tumor response.
  • [MeSH-major] Adenocarcinoma, Mucinous / secondary. Colloids / metabolism. Mucins / metabolism. Radiotherapy, Adjuvant. Rectal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Survival Rate

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  • (PMID = 15832083.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Colloids; 0 / Mucins
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