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Items 1 to 32 of about 32
1. Rosbottom KJ, Michie B, Boyce S: Metastasis of recurrent colonic adenocarcinoma to the mouth. BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasis of recurrent colonic adenocarcinoma to the mouth.
  • Colorectal adenocarcinoma is a common cancer; however, reports of metastases to the oral region are uncommon.
  • Oral metastases often indicate disseminated disease, the prognosis is poor and management is often palliative.
  • We report the case of a 73-year-old man with recurrent metastatic disease who presented 2 years following his initial surgery for a left-sided colonic adenocarcinoma with a painful oral tumour.
  • Biopsy confirmed adenocarcinoma with similar features to the original colonic tumour; the patient went on to have palliation of his symptoms with radiotherapy.

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  • [Cites] J Oral Surg. 1975 Jan;33(1):53-6 [1053651.001]
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  • (PMID = 21754956.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028428
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2. Damodaran D, Kathiresan N, Satheesan B: Oral cavity metastasis: An unusual presentation of carcinoma prostate. Indian J Urol; 2008 Jan;24(1):112-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oral cavity metastasis: An unusual presentation of carcinoma prostate.
  • Oral cavity cancers form the third most common cancers among men in south India.
  • The oral cavity is a very rare site for metastases and has been described in various cancers, particularly lung, breast, kidney and colon carcinoma.
  • Here a very rare case of a buccal metastasis from prostate carcinoma that was originally evaluated as a primary oral cavity malignancy is presented.
  • Histopathological examination of a biopsy of the lesion revealed papillary adenocarcinoma Grade II, nuclear Grade II, which initiated the evaluation of prostate.
  • On evaluation diagnosis of carcinoma prostate was made which was confirmed by immunohistochemistry for PSA.

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  • [Cites] Int J Cancer. 2005 Sep 20;116(5):740-54 [15849747.001]
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  • (PMID = 19468372.001).
  • [ISSN] 0970-1591
  • [Journal-full-title] Indian journal of urology : IJU : journal of the Urological Society of India
  • [ISO-abbreviation] Indian J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2684236
  • [Keywords] NOTNLM ; Oral cavity metastasis / prostate cancer / prostate specific antigen immunohistochemistry
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3. Pintor MF, Figueroa L, Martínez B: Polymorphous low grade adenocarcinoma: review and case report. Med Oral Patol Oral Cir Bucal; 2007 Dec;12(8):E549-51
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Polymorphous low grade adenocarcinoma: review and case report.
  • Polymorphous Low-Grade Adenocarcinoma is a rare, malignant salivary gland tumor, which is found almost exclusively in minor salivary glands.
  • It is usually located in the hard or soft palate, although it may be found in the rest of the oral cavity too.
  • An incisional biopsy was carried out, and once the polymorphous low-grade adenocarcinoma diagnosis had been stated, the patient was sent to the Head and Neck Surgery Service of the Military Hospital, where the lesion was treated by wide surgical excision followed by radiation therapy.
  • [MeSH-major] Adenocarcinoma. Salivary Gland Neoplasms

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  • (PMID = 18059236.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 10
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4. Storck K, Hadi UM, Simpson R, Ramer M, Brandwein-Gensler M: Sinonasal renal cell-like adenocarcinoma: a report on four patients. Head Neck Pathol; 2008 Jun;2(2):75-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sinonasal renal cell-like adenocarcinoma: a report on four patients.
  • BACKGROUND: We have described an unusual sinonasal neoplasm which is a histological mimic of renal cell carcinoma (RCC) and coined the nosological classification "sinonasal renal cell-like adenocarcinoma" (SRCLA) to describe this unusual entity.
  • Three tumors were in the nasal cavity and one was in the nasopharynx.
  • All patients are disease-free, based on endoscopy and/or radiography, 2, 4, 5 and 8 years after diagnosis.
  • CONCLUSION: Sinonasal renal cell-like adenocarcinoma is a rare and distinct entity noteworthy in its resemblance to RCC.
  • [MeSH-major] Adenocarcinoma / pathology. Nasal Cavity / pathology. Nasopharyngeal Neoplasms / pathology. Paranasal Sinus Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Kidney Neoplasms / pathology. Male. Middle Aged. Young Adult

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  • [Cites] Indian J Pathol Microbiol. 2003 Jan;46(1):93-5 [15027741.001]
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  • (PMID = 20614326.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2807555
  • [Keywords] NOTNLM ; Renal cell carcinoma / Renal cell-like carcinoma / Sinonasal / Vermeer
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5. Paleri V, Robinson M, Bradley P: Polymorphous low-grade adenocarcinoma of the head and neck. Curr Opin Otolaryngol Head Neck Surg; 2008 Apr;16(2):163-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Polymorphous low-grade adenocarcinoma of the head and neck.
  • PURPOSE OF REVIEW: Polymorphous low-grade adenocarcinoma is an entity described in 1984.
  • The natural history of polymorphous low-grade adenocarcinoma is distinct from other malignant salivary tumours.
  • RECENT FINDINGS: Polymorphous low-grade adenocarcinoma is a slow-growing tumour that is locally invasive.
  • The most common presentation is that of a lump in the oral cavity, usually on the palate.
  • Diagnosis is established after a biopsy because cytological studies are not helpful.
  • The role of radiation therapy is not clear in the management of polymorphous low-grade adenocarcinoma.
  • SUMMARY: Polymorphous low-grade adenocarcinoma is primarily a pathologic diagnosis.
  • [MeSH-major] Adenocarcinoma / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 18327037.001).
  • [ISSN] 1531-6998
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 60
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6. Krawczyk M, Mykała-Cieśla J, Kołodziej-Jaskuła A: Acanthosis nigricans as a paraneoplastic syndrome. Case reports and review of literature. Pol Arch Med Wewn; 2009 Mar;119(3):180-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acanthosis nigricans (AN) is a skin disorder characterized by focal or diffuse hyperkeratosis symmetric hyperpigmentation of the skin and oral cavity mucosa.
  • Both have been associated with gastric adenocarcinoma.
  • [MeSH-major] Acanthosis Nigricans / complications. Acanthosis Nigricans / diagnosis. Adenocarcinoma / diagnosis. Adenocarcinoma / etiology. Stomach Neoplasms / diagnosis. Stomach Neoplasms / etiology

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  • (PMID = 19514649.001).
  • [Journal-full-title] Polskie Archiwum Medycyny Wewnetrznej
  • [ISO-abbreviation] Pol. Arch. Med. Wewn.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 8
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7. Angiero F, Stefani M: Hyalinizing clear cell carcinoma arising on the anterior palatoglossal arch. Anticancer Res; 2007 Nov-Dec;27(6C):4271-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hyalinizing clear cell carcinoma (HCCC) is very rare in the oral cavity, arising more frequently in the minor salivary glands.
  • This report focuses on the heterogeneous group of clear cell neoplasms with the intent of pointing out some aspects that may contribute to forming a diagnosis of HCCC, and which, above all enable us to distinguish this neoplasm from other very similar forms occurring in the oral cavity.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Mouth Neoplasms / pathology. Palatal Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Hyalin. Immunohistochemistry. Middle Aged. Palate, Hard / pathology. Palate, Hard / surgery. Salivary Gland Neoplasms / pathology

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  • (PMID = 18214031.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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8. Bhutani M, Pathak AK, Fan YH, Liu DD, Lee JJ, Tang H, Kurie JM, Morice RC, Kim ES, Hong WK, Mao L: Oral epithelium as a surrogate tissue for assessing smoking-induced molecular alterations in the lungs. Cancer Prev Res (Phila); 2008 Jun;1(1):39-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oral epithelium as a surrogate tissue for assessing smoking-induced molecular alterations in the lungs.
  • The lungs and oral cavity of smokers are exposed to tobacco carcinogens.
  • We hypothesized that tobacco-induced molecular alterations in the oral epithelium are similar to those in the lungs, and thus the oral epithelium may be used as a surrogate tissue for assessing alterations in the lungs.
  • We used methylation-specific PCR to analyze promoter methylation of the p16 and FHIT genes at baseline and 3 months after intervention in 1,774 oral and bronchial brush specimens from 127 smokers enrolled in a randomized placebo-controlled chemoprevention trial.
  • The association between methylation patterns in oral tissues and bronchial methylation indices (methylated sites / total sites per subject) was analyzed in a blinded fashion.
  • At baseline, promoter methylation in bronchial tissue was present in 23% of samples for p16, 17% for FHIT, and 35% for p16 and FHIT; these percentages were comparable to methylation in oral tissue: 19% (p16), 15% (FHIT), and 31% (p16 and FHIT).
  • Data from both oral and bronchial tissues were available for 125 individuals, in whom the two sites correlated strongly with respect to alterations (P < 0.0001 for both p16 and FHIT).
  • At baseline, the mean bronchial methylation index was far higher in patients with oral tissue methylation (in either of the two genes; 39 patients) than in patients without oral tissue methylation (86 patients): 0.53 +/- 0.29 versus 0.27 + 0.26 methylation index (P < 0.0001).
  • Our results support the potential of oral epithelium as a surrogate tissue for assessing tobacco-induced molecular damage in the lungs and thus have important implications for designing future lung cancer prevention trials and for research into the risk and early detection of lung cancer.

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  • [CommentIn] Cancer Prev Res (Phila). 2008 Jun;1(1):12-4 [19138931.001]
  • (PMID = 19138934.001).
  • [ISSN] 1940-6215
  • [Journal-full-title] Cancer prevention research (Philadelphia, Pa.)
  • [ISO-abbreviation] Cancer Prev Res (Phila)
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P01 CA091844; United States / NCI NIH HHS / CA / P30 CA016672; United States / NCI NIH HHS / CA / CA-16672; United States / NCI NIH HHS / CA / CA091844
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Neoplasm Proteins; 0 / fragile histidine triad protein; EC 3.6.- / Acid Anhydride Hydrolases
  • [Other-IDs] NLM/ NIHMS630678; NLM/ PMC4183362
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9. González-García R, Naval-Gías L, Rodríguez-Campo FJ, Sastre-Pérez J, Gamallo C: Adenocarcinoma of the ethmoidal and nasal mucosa: lateral rhinotomy as a more conservative approach. Acta Otolaryngol; 2006 Aug;126(8):878-80
MedlinePlus Health Information. consumer health - Nasal Cancer.

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  • [Title] Adenocarcinoma of the ethmoidal and nasal mucosa: lateral rhinotomy as a more conservative approach.
  • Malignant neoplasms of the nasal cavity and paranasal sinuses are infrequent.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma, Papillary / diagnosis. Ethmoid Sinus. Nasal Mucosa. Nose Neoplasms / diagnosis. Paranasal Sinus Neoplasms / diagnosis

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  • (PMID = 16846933.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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10. Andreadis D, Nomikos A, Epivatianos A, Poulopoulos A, Barbatis C: Basaloid squamous cell carcinoma versus basal cell adenocarcinoma of the oral cavity. Pathology; 2005 Dec;37(6):560-3
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Basaloid squamous cell carcinoma versus basal cell adenocarcinoma of the oral cavity.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Immunohistochemistry


11. Dib LL, Soares AL, Sandoval RL, Nannmark U: Breast metastasis around dental implants: a case report. Clin Implant Dent Relat Res; 2007 Jun;9(2):112-5
MedlinePlus Health Information. consumer health - Breast Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Metastases to the oral cavity and to the jaws are rare; hence, the clinical manifestations of the oral metastasis lesion could frequently be simulating general pathologic entities, making the diagnosis a challenging process to the dental team.
  • PURPOSE: Careful clinical examination is a valuable help in diagnosing oral lesions, which can improve the quality of life of patients and reduce the risks of oral complications.
  • RESULTS: Clinical examination, x-ray, and histopathology revealed that the patients suffered from a metastatic lesion, primary tumor being an adenocarcinoma of the breast diagnosed at the same time.
  • [MeSH-major] Adenocarcinoma / secondary. Breast Neoplasms / pathology. Dental Implants. Gingival Neoplasms / secondary

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  • (PMID = 17535335.001).
  • [ISSN] 1523-0899
  • [Journal-full-title] Clinical implant dentistry and related research
  • [ISO-abbreviation] Clin Implant Dent Relat Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Dental Implants
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12. Heinroth S, Bilkenroth U, Eckert AW, Maurer P: [Bone metastases in the maxilla as first manifestation of renal cell cancer. A case report]. Mund Kiefer Gesichtschir; 2006 Jan;10(1):42-5
MedlinePlus Health Information. consumer health - Kidney Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Bone metastases in the upper jaw are relatively rare but not unusual in oral and maxillofacial surgery.
  • CASE REPORT: We describe a 53-year-old female patient who suffered from a tumor in the oral cavity.
  • The first histological and clinical diagnosis revealed a granuloma pyogenicum.
  • Diagnostic procedures detected an adenocarcinoma of the left kidney with pelvic metastases.
  • CONCLUSION: The present case report demonstrates how difficult it can be to provide the right pathological diagnosis in biopsy material even regarding obvious malignancy.
  • [MeSH-major] Carcinoma, Renal Cell / secondary. Kidney Neoplasms / diagnosis. Maxillary Neoplasms / secondary
  • [MeSH-minor] Biopsy, Fine-Needle. Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Bone Neoplasms / secondary. Bone Neoplasms / therapy. Combined Modality Therapy. Diagnosis, Differential. Disease Progression. Female. Humans. Kidney / pathology. Maxilla / pathology. Middle Aged. Pelvic Neoplasms / diagnosis. Pelvic Neoplasms / pathology. Pelvic Neoplasms / secondary. Pelvic Neoplasms / therapy

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  • [Cites] Eur J Cancer. 2005 Jun;41(9):1246-53 [15939260.001]
  • [Cites] Int J Cancer. 2001 May 15;92(4):577-82 [11304694.001]
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  • (PMID = 16402238.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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13. Lutz JC, El-Bouihi M, Vidal N, Fricain JC, Robert M, Deminière C, Zwetyenga N: Mandibular metastases from an ileum stromal tumor. Rev Stomatol Chir Maxillofac; 2008 Dec;109(6):399-402
MedlinePlus Health Information. consumer health - Intestinal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Metastatic disease of the jaws is unusual and accounts for 1 to 4% of oral cavity malignancies.
  • Jaw metastases from the gastrointestinal (GI) tract usually evolve from adenocarcinoma of the esophagus, colon, and rectum.
  • The oral mucosa was macroscopically normal.
  • The patient was treated with imatinib but died 11 months after the diagnosis.
  • DISCUSSION: The prevalence of GIST is low but the true incidence may be higher because of under-diagnosis.
  • GIST should be included in the differential diagnosis of intramandibular tumor in patients with prior or current non-oral malignancy.

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  • (PMID = 19010506.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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14. Pozzi EC, Altermatt HJ, Rees TD, Bornstein MM: Exophytic mass of the gingiva as the first manifestation of metastatic pulmonary adenocarcinoma. J Periodontol; 2008 Jan;79(1):187-91
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  • [Title] Exophytic mass of the gingiva as the first manifestation of metastatic pulmonary adenocarcinoma.
  • BACKGROUND: Metastasis of a malignant tumor to the oral cavity is rare, but it can be the first manifestation of a primary tumor.
  • METHODS: The clinicopathologic features of a gingival metastasis originating from lung adenocarcinoma in a female patient are described.
  • Finally, a biopsy of the lungs confirmed a poorly differentiated adenocarcinoma with multiple metastases, including the oral cavity.
  • CONCLUSIONS: An exophytic lesion on the gingiva can be the first sign of metastatic adenocarcinoma to the oral mucosa.
  • [MeSH-major] Adenocarcinoma / secondary. Gingival Neoplasms / secondary. Lung Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Fatal Outcome. Female. Homeodomain Proteins / analysis. Humans. Immunohistochemistry. Keratin-7 / analysis. Mandible. Middle Aged. Nuclear Proteins / analysis. Transcription Factors / analysis

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  • (PMID = 18166110.001).
  • [ISSN] 0022-3492
  • [Journal-full-title] Journal of periodontology
  • [ISO-abbreviation] J. Periodontol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / Keratin-7; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / thyroid nuclear factor 1
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15. Selim AA, Shaheen S, Lockshin N, Khachemoune A: Cutaneous metastasis of uterine adenocarcinoma: a case report and review of the literature. Cutis; 2009 Jul;84(1):33-8
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  • [Title] Cutaneous metastasis of uterine adenocarcinoma: a case report and review of the literature.
  • Cutaneous metastases from cancer are relatively uncommon in clinical practice but when present may herald the diagnosis of internal malignancy.
  • The most common sources of primary cancer are the breasts, lungs, large bowel, oral cavity, kidneys, stomach, ovaries, and malignant melanoma.
  • Despite the high incidence of uterine adenocarcinoma, cutaneous metastases are uncommon.
  • The diagnosis of cutaneous metastatic carcinoma hinges on histopathologic evaluation of the involved skin.
  • We discuss and review the diagnosis and management of cutaneous metastasis of uterine adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Skin Neoplasms / secondary. Uterine Neoplasms / pathology
  • [MeSH-minor] Aged. Antineoplastic Agents / therapeutic use. Diagnosis, Differential. Female. Humans

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  • (PMID = 19743722.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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16. Pires FR, Azevedo RS, Ficarra G, Cardoso AS, Carlos R, Kowalski LP, de Almeida OP: Metastatic renal cell carcinoma to the oral cavity and clear cell mucoepidermoid carcinoma: comparative clinicopathologic and immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Apr;109(4):e22-7
Hazardous Substances Data Bank. Carminic acid .

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  • [Title] Metastatic renal cell carcinoma to the oral cavity and clear cell mucoepidermoid carcinoma: comparative clinicopathologic and immunohistochemical study.
  • BACKGROUND: Metastatic clear cell renal cell carcinoma (CCRCC) should be considered in differential diagnosis of intraoral clear cell tumors, including mucoepidermoid carcinoma (MEC).
  • OBJECTIVE AND STUDY DESIGN: We compared the clinical, histologic, histochemical, and immunohistochemical characteristics of 9 oral metastatic CCRCCs and 8 intraoral clear cell MECs.
  • RESULTS: Oral metastatic CCRCC affected salivary-gland containing tissues in 7 cases (78%).
  • Microscopically, oral metastasis revealed a proliferation of neoplastic clear cells arranged in an alveolar pattern with central blood vessels, features that were not seen in any intraoral clear cell MEC.
  • Immunohistochemistry showed similarities in cytokeratin expression; vimentin and CD10 were expressed in all oral metastatic CCRCCs but in only 1 clear cell MEC each.
  • CONCLUSIONS: Besides clinical history, the alveolar pattern, vessel distribution, absence of mucicarmine staining, and vimentin and CD10 immunoexpression are useful in histologic differential diagnosis of CCRCC and clear cell MEC.
  • [MeSH-major] Adenocarcinoma, Clear Cell / secondary. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Renal Cell / secondary. Mouth Neoplasms / secondary
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carmine. Cell Nucleus / ultrastructure. Coloring Agents. Cytoplasm / ultrastructure. Diagnosis, Differential. Female. Hemorrhage / pathology. Histocytochemistry. Humans. Immunohistochemistry. Keratins / analysis. Male. Microvessels / pathology. Middle Aged. Neprilysin / analysis. Salivary Gland Neoplasms / blood supply. Salivary Gland Neoplasms / pathology. Salivary Gland Neoplasms / secondary. Vimentin / analysis

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  • [Copyright] Copyright 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20303042.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / Vimentin; 51395-97-2 / mucicarmine; 68238-35-7 / Keratins; CID8Z8N95N / Carmine; EC 3.4.24.11 / Neprilysin
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17. Wang H, Yao J, Solomon M, Axiotis CA: Sebaceous carcinoma of the oral cavity: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Aug;110(2):e37-40
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  • [Title] Sebaceous carcinoma of the oral cavity: a case report and review of the literature.
  • We discuss the differential diagnosis and histogenesis.
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Mouth Neoplasms / pathology

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  • [Copyright] Copyright 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20659693.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Androgen
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18. Fukui D, Bando G, Ishikawa Y, Kadota K: Adenosquamous carcinoma with cilium formation, mucin production and keratinization in the nasal cavity of a red fox (Vulpes vulpes schrencki). J Comp Pathol; 2007 Aug-Oct;137(2-3):142-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenosquamous carcinoma with cilium formation, mucin production and keratinization in the nasal cavity of a red fox (Vulpes vulpes schrencki).
  • A diagnosis of adenosquamous carcinoma was made in an 11-year-old red fox.
  • The nasal and oral lesions were composed of adenocarcinomatous cells and squamous cells, the latter predominating in the oral lesions.
  • Although inconspicuous in the oral cavity and marrow, ciliated cells with or without mucin were observed in the adenocarcinomatous and cystic elements.
  • Neoplastic basal cells and less-differentiated adenocarcinoma cells, which were identifiable by immunolabelling for cytokeratin 5 (CK5) and CK18, were considered to be pluripotential.
  • [MeSH-minor] Animals. Bone Marrow / pathology. Keratin-18 / metabolism. Keratin-5 / metabolism. Nasal Cavity

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  • (PMID = 17645890.001).
  • [ISSN] 0021-9975
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Keratin-18; 0 / Keratin-5; 0 / Mucins; 68238-35-7 / Keratins
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19. Lai G, Nemolato S, Lecca S, Parodo G, Medda C, Faa G: The role of immunohistochemistry in the diagnosis of hyalinizing clear cell carcinoma of the minor salivary gland: a case report. Eur J Histochem; 2008 Oct-Dec;52(4):251-4
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  • [Title] The role of immunohistochemistry in the diagnosis of hyalinizing clear cell carcinoma of the minor salivary gland: a case report.
  • A case of hyalinizing clear cell carcinoma (HCCC) of the minor salivary glands of the oral cavity is reported.
  • These findings confirmed the diagnosis of HCCC of minor salivary glands of the oral cavity.
  • The clinical presentation, the immunohistochemical pattern and the role of cytokeratins in the differential diagnosis of HCCC are discussed with a review of the literature.
  • [MeSH-major] Adenocarcinoma, Clear Cell / diagnosis. Immunohistochemistry / methods. Salivary Gland Neoplasms / diagnosis. Salivary Glands, Minor / pathology
  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Biomarkers, Tumor / analysis. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Diagnosis, Differential. Female. Humans. Hyalin / metabolism. Keratins / analysis. Melanoma / diagnosis. Melanoma / secondary. Middle Aged. Myoepithelioma / diagnosis

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  • (PMID = 19109100.001).
  • [ISSN] 1121-760X
  • [Journal-full-title] European journal of histochemistry : EJH
  • [ISO-abbreviation] Eur J Histochem
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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20. Doobaree IU, Landis SH, Linklater KM, El-Hariry I, Moller H, Tyczynski J: Head and neck cancer in South East England between 1995-1999 and 2000-2004: An estimation of incidence and distribution by site, stage and histological type. Oral Oncol; 2009 Sep;45(9):809-14
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  • The three commonest HNC sites were intra-oral cavity, larynx and tonsil.
  • Males were two to six times as likely as females to be diagnosed with HNC and there was a trend toward younger age at diagnosis over time.
  • Significant increases in the incidence rate of intra-oral cavity cancer for both sexes and tonsillar cancer among males were observed.
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Adolescent. Adult. Age Distribution. Aged. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. Child. Child, Preschool. England / epidemiology. Female. Humans. Incidence. Infant. Infant, Newborn. Male. Middle Aged. Registries. Sex Distribution. Young Adult

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  • (PMID = 19251472.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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21. Kruse AL, Luebbers HT, Obwegeser JA, Edelmann L, Graetz KW: Temporomandibular disorders associated with metastases to the temporomandibular joint: a review of the literature and 3 additional cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Aug;110(2):e21-8
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  • INTRODUCTION: Metastases involving the oral cavity account for 1% to 8% of all malignancies in the oral cavity Involvement of the temporomandibular joint (TMJ) is uncommon.
  • Adenocarcinoma was predominant (72.97%).
  • CONCLUSION: Establishing an exact diagnosis of metastatic lesions in the TMJ can provide a diagnostic challenge.
  • Clinicians should include the suspicion of cancer in the differential diagnosis, in particular when patients have a previous history of malignant neoplasm or do not respond to treatment appropriately.
  • [MeSH-major] Adenocarcinoma / secondary. Carcinoma / secondary. Mandibular Condyle / pathology. Mandibular Neoplasms / secondary. Temporomandibular Joint Disorders / etiology. Thyroid Neoplasms / pathology

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  • [Copyright] Copyright 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20659692.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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22. Gomes CC, Lacerda JC, Pimenta FJ, do Carmo MA, Gomez RS: Intraoral sebaceous carcinoma. Eur Arch Otorhinolaryngol; 2007 Jul;264(7):829-32
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  • Intraoral sebaceous carcinoma (SC) is a rare tumour in the oral cavity thought to arise from malignant transformation of oral sebaceous glands.
  • [MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Mouth Neoplasms / diagnosis. Sebaceous Gland Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Combined Modality Therapy. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged. Radiography, Panoramic. Tomography, X-Ray Computed

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  • (PMID = 17285332.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
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23. Mayr SI, Hafizovic K, Waldfahrer F, Iro H, Kütting B: Characterization of initial clinical symptoms and risk factors for sinonasal adenocarcinomas: results of a case-control study. Int Arch Occup Environ Health; 2010 Aug;83(6):631-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Sinonasal adenocarcinoma is a rare cancer, frequently associated with occupational exposure to inhalable wood dust.
  • Location and long latency make early diagnosis difficult.
  • METHODS: Of 58 patients, 31 diagnosed with sinonasal adenocarcinoma (cases) between 1973 and 2007 were identified and underwent standardized interview on clinical data.
  • A total of 85 patients diagnosed over the same period with carcinoma of the oral cavity served as controls.
  • RESULTS: The ethmoid was confirmed as the predominant site of adenocarcinoma associated with wood dust exposure, whereas the nasal cavity was most commonly affected in patients denying any exposure to wood dust.
  • The main initial clinical symptoms were nasal obstruction 6 months (71%) and epistaxis 4 years (41.9%) prior to diagnosis.
  • [MeSH-major] Adenocarcinoma / epidemiology. Adenocarcinoma / physiopathology. Paranasal Sinus Neoplasms / epidemiology. Paranasal Sinus Neoplasms / physiopathology

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  • (PMID = 19885670.001).
  • [ISSN] 1432-1246
  • [Journal-full-title] International archives of occupational and environmental health
  • [ISO-abbreviation] Int Arch Occup Environ Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Dust
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24. Li X, Liu HG, Xie XJ, Han YD, Li M: [Clinicopathologic study of sinonasal teratocarcinosarcoma and its contrast with olfactory neuroblastoma]. Zhonghua Bing Li Xue Za Zhi; 2008 Jul;37(7):458-64
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To study the clinicopathologic features, diagnosis and differential diagnosis of sinonasal teratocarcinosarcoma (SNTCS) and olfactory neuroblastoma (ONB), and to discuss the histogenesis and possible relationship between SNTCS and ONB.
  • The carcinoma component exhibited mostly adenocarcinoma and squamous cell carcinoma, whereas the sarcoma component mostly exhibited rhabdomyosarcoma, leiomyosarcoma, and fibrosarcoma.
  • In the immature embryonic tissue, rudimentary organs were formed, with fetal clear cell squamous epithelium lining present on the nasal and oral cavities surface.
  • As SNTCS may demonstrate a multiplicity of structures and pleomorphism, inadequate sampling at biopsy, therefore, may lead to errors in diagnosis.
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged. Nasal Cavity / pathology. Phosphopyruvate Hydratase. Rhabdomyosarcoma / pathology

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  • (PMID = 19035117.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 4.2.1.11 / Phosphopyruvate Hydratase
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25. Migliario M, Rimondini L, Valente G: Benign fibrous histiocytoma of the lower lip. J Craniofac Surg; 2010 Nov;21(6):2024-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To our knowledge, involvement of the soft tissue of the oral cavity is rare.
  • This rare tumor should be considered in the differential diagnosis of the oral soft-tissue neoplasms.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Lip Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma, Follicular / pathology. Diagnosis, Differential. Female. Giant Cells / pathology. Hemosiderin / analysis. Histiocytes / pathology. Humans. Lymphocytes / pathology. Middle Aged. Neoplasms, Second Primary / diagnosis. Thyroid Neoplasms / pathology

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  • (PMID = 21119493.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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26. Chen HL, Chang WH, Shih SC, Pang KK, Bair MJ: Trismus and trigeminal neuralgia in one patient with colon cancer. J Natl Med Assoc; 2008 Jun;100(6):740-2
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  • A 64-year-old man got trismus and trigeminal neuralgia under the diagnosis of colon cancer with mandibular metastasis after emergency appendectomy and elective hemicolectomy.
  • He died six months after diagnosis.
  • Metastatic tumors to the oral cavity are relatively uncommon.
  • They are found most commonly in the mandible, and 70% of cases are adenocarcinoma-most commonly from breast and lung, followed by adrenals, kidneys, prostate, thyroid and colon.
  • Tissue proof is needed to confirm the diagnosis.
  • However, the prognosis is grim, with the mean survival after diagnosis being only about 6-7 months.
  • [MeSH-major] Adenocarcinoma / secondary. Colonic Neoplasms / pathology. Mandibular Neoplasms / secondary. Trigeminal Neuralgia / etiology. Trismus / etiology

  • Genetic Alliance. consumer health - Trigeminal neuralgia.
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  • (PMID = 18595580.001).
  • [ISSN] 1943-4693
  • [Journal-full-title] Journal of the National Medical Association
  • [ISO-abbreviation] J Natl Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Ahmad Z, Azad NS, Yaqoob N, Husain A, Ahsan A, Khan AN, Ahmed R, Kayani N, Pervez S, Hassan SH: Frequency of primary solid malignant neoplasms in both sexes, as seen in our practice. J Ayub Med Coll Abbottabad; 2007 Jan-Mar;19(1):53-5
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  • RESULTS: Squamous cell carcinoma of oral cavity was the commonest malignant neoplasm in males followed by diffuse Large B cell, Non-Hodgkin's lymphoma and Prostatic adenocarcinoma.
  • In females, infiltrating Ductal carcinoma of the breast was overwhelmingly the commonest malignant neoplasm followed by Squamous cell carcinoma of the oral cavity and esophagus.
  • Carcinoma of oral cavity is very common in our population in both sexes.
  • [MeSH-major] Lymphoma, B-Cell / diagnosis. Lymphoma, Large B-Cell, Diffuse / diagnosis. Lymphoma, Non-Hodgkin / epidemiology. Neoplasms, Squamous Cell / epidemiology. Prostatic Neoplasms / epidemiology

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  • (PMID = 17867482.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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28. Mitsuya J, Hara H, Ito K, Ishii N, Hashimoto T, Terui T: Metastatic ovarian carcinoma-associated subepidermal blistering disease with autoantibodies to both the p200 dermal antigen and the gamma 2 subunit of laminin 5 showing unusual clinical features. Br J Dermatol; 2008 Jun;158(6):1354-7
MedlinePlus Health Information. consumer health - Ovarian Cancer.

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  • Clinical features showed severe blisters and erosions on multiple mucous membranes (i.e. lip, oral cavity, nose, eye, genitalia and anus) and on both the periungual and subungual regions.
  • [MeSH-major] Adenocarcinoma, Clear Cell / secondary. Antigens, Neoplasm / immunology. Autoantibodies / immunology. Blister / immunology. Epidermolysis Bullosa Acquisita / diagnosis. Laminin / immunology. Ovarian Neoplasms / complications

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  • (PMID = 18294311.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Autoantibodies; 0 / Immunoglobulin G; 0 / LAMC2 protein, human; 0 / Laminin; 0 / antigen p200
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29. Parekh DJ, Lin WC, Herrell SD: Optical spectroscopy characteristics can differentiate benign and malignant renal tissues: a potentially useful modality. J Urol; 2005 Nov;174(5):1754-8
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  • PURPOSE: Promising results of optical signals have been reported in the literature for the diagnosis of Barrett's esophagus, oral cavity lesions, brain tumor margins, cervical intraepithelial neoplasia, skin cancer and bladder cancer.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Precancerous Conditions / pathology. Spectrometry, Fluorescence
  • [MeSH-minor] Case-Control Studies. Diagnosis, Differential. Female. Humans. Kidney / pathology. Male. Reference Values. Sampling Studies. Sensitivity and Specificity. Tissue Culture Techniques

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  • [CommentIn] J Urol. 2005 Nov;174(5):1723-4 [16217270.001]
  • (PMID = 16217277.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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30. Sasaki H, Ohara N, Minamikawa T, Umeda M, Komori T, Kojima N, Takemura N, Morita H, Sugihara R, Enoki E, Itoh T: Gingival metastasis from ovarian mucinous cystadenocarcinoma as an initial manifestation (a rare case report). Kobe J Med Sci; 2008;54(3):E174-82
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The metastasis of malignant tumors to the oral cavity remains a rare clinical entity.
  • Most metastatic tumors have the propensity for involving the mandible rather than the oral soft tissues.
  • There is little information regarding metastatic ovarian cancer to the oral cavity.
  • A biopsy taken from the gingiva showed mucinous adenocarcinoma, indicating the gingival metastasis of undiscovered primary cancer.
  • Based on the imaging studies, the diagnosis of the gingival metastasis of an ovarian cancer was suspected.
  • The histology of surgical specimen confirmed the gingival metastasis of ovarian mucinous adenocarcinoma.
  • This case emphasizes that although rare, metastatic ovarian cancer to the gingiva should be included in the differential diagnosis of tumors in the oral cavity.

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  • (PMID = 19246966.001).
  • [ISSN] 1883-0498
  • [Journal-full-title] The Kobe journal of medical sciences
  • [ISO-abbreviation] Kobe J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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31. Reid-Nicholson M, Kavuri S, Ustun C, Crawford J, Nayak-Kapoor A, Ramalingam P: Plasmablastic lymphoma: Cytologic findings in 5 cases with unusual presentation. Cancer; 2008 Oct 25;114(5):333-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Plasmablastic lymphoma (PBL) is a rare form of non-Hodgkin lymphoma that was once believed to occur primarily in the oral cavity of human immunodeficiency virus-positive individuals.
  • Two patients had the acquired immunodeficiency syndrome and 3 had second non-PBL related malignancies including endometrial carcinoma, lung adenocarcinoma, and small lymphocytic lymphoma.
  • However, although these findings may suggest PBL, a definitive diagnosis requires adjunctive studies including immunohistochemistry and flow cytometry.

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  • [Copyright] (c) 2008 American Cancer Society.
  • (PMID = 18683216.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Sidransky D: The oral cavity as a molecular mirror of lung carcinogenesis. Cancer Prev Res (Phila); 2008 Jun;1(1):12-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The oral cavity as a molecular mirror of lung carcinogenesis.

  • MedlinePlus Health Information. consumer health - Lung Cancer.
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  • [CommentOn] Cancer Prev Res (Phila). 2008 Jun;1(1):39-44 [19138934.001]
  • (PMID = 19138931.001).
  • [ISSN] 1940-6215
  • [Journal-full-title] Cancer prevention research (Philadelphia, Pa.)
  • [ISO-abbreviation] Cancer Prev Res (Phila)
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / 5U01 CA084986; United States / NIDCR NIH HHS / DE / P50 DE019032; United States / NIDCR NIH HHS / DE / R37 DE012588; United States / NIDCR NIH HHS / DE / R01 DE012588; United States / NCI NIH HHS / CA / U01 CA084986
  • [Publication-type] Comment; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS695561; NLM/ PMC4604561
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