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1. Huang CT, Hong RL: Nasion swelling as the presenting symptom of lung adenocarcinoma. J Thorac Oncol; 2009 Apr;4(4):555-8
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  • [Title] Nasion swelling as the presenting symptom of lung adenocarcinoma.
  • Here, we reported a patient of lung adenocarcinoma presenting with nasion swelling because of metastasis to the paranasal sinuses.
  • Adenocarcinoma was the most commonly encountered histologic subtype, and modern combination chemotherapy was probably the most effective treatment modality.
  • A thorough history taking, ear, nose, and throat examination, and laboratory investigations are of paramount importance to achieve a correct diagnosis.
  • [MeSH-major] Adenocarcinoma / pathology. Lung Neoplasms / pathology. Paranasal Sinus Neoplasms / secondary
  • [MeSH-minor] Female. Humans. Middle Aged

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  • (PMID = 19333075.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
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2. bin Sabir Husin Athar PP, bte Ahmad Norhan N, bin Saim L, bin Md Rose I, bte Ramli R: Metastasis to the sinonasal tract from sigmoid colon adenocarcinoma. Ann Acad Med Singapore; 2008 Sep;37(9):788-3
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  • [Title] Metastasis to the sinonasal tract from sigmoid colon adenocarcinoma.
  • INTRODUCTION: Metastatic adenocarcinoma from the gastrointestinal tract to the sinonasal tract is rare.
  • The histological morphology of this lesion is indistinguishable from the colonic variant of primary sinus adenocarcinoma or intestinal-type adenocarcinoma (ITAC).
  • CLINICAL PICTURE: This is a report of a case of metastatic adenocarcinoma of colorectal origin to the paranasal sinuses in a 52-year-old female who was previously treated for adenocarcinoma of the sigmoid colon.
  • The sinonasal neoplastic tissue showed marked positivity for carcinoembryonic antigen and expressed cytokeratin 20, which differentiates metastatic colonic adenocarcinoma from ITAC.
  • TREATMENT/OUTCOME: The patient received palliative radiation but died 3 months after the diagnosis.
  • CONCLUSION: Distinguishing metastatic adenocarcinoma from gastrointestinal tract from ITAC can be difficult.
  • [MeSH-major] Adenocarcinoma / secondary. Colorectal Neoplasms / pathology. Paranasal Sinus Neoplasms / secondary
  • [MeSH-minor] Carcinoembryonic Antigen / metabolism. Fatal Outcome. Female. Humans. Keratin-20 / metabolism. Middle Aged. Palliative Care

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  • (PMID = 18989497.001).
  • [ISSN] 0304-4602
  • [Journal-full-title] Annals of the Academy of Medicine, Singapore
  • [ISO-abbreviation] Ann. Acad. Med. Singap.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Keratin-20
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3. Sabbatani S, Fulgaro C, Latini G, Burzi M, Manfredi R: Associated actinomycosis and rhinopharyngeal adenocarcinoma during HIV infection: diagnostic and therapeutic issues. Infez Med; 2008 Sep;16(3):164-72
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  • [Title] Associated actinomycosis and rhinopharyngeal adenocarcinoma during HIV infection: diagnostic and therapeutic issues.
  • An extremely infrequent episode of nasopharyngeal actinomycosis associated with squamous adenocarcinoma occurred in an HIV-infected male patient with a previous diagnosis of AIDS, treated with combined antiretroviral therapy taken with insufficient adherence, such that a satisfactory immune system recovery (as expressed by a CD4 lymphocyte count persistently above 400 cells/mcl), contrasted with a low-level persistence of detectable HIV viraemia, and enlarged genotypic resistance mutations.
  • Despite appropriate and timely diagnostic assessment carried out with repeated, combined computerized tomography, magnetic resonance imaging, and fiberoptic rhinoscopy with biopsy and histopathologic studies, the final diagnosis of a combined dual infectious-neoplastic pathology occurred only after a demolishing surgical intervention and subsequent pathology studies.
  • To the best of our knowledge, this is the first described case of actinomycosis associated with a local, underlying squamous cell adenocarcinoma of the same ear, nose, and throat district in either HIV-infected or HIV-non-infected subjects.
  • [MeSH-minor] Administration, Inhalation. Anti-Bacterial Agents / therapeutic use. Antiretroviral Therapy, Highly Active. Brain Neoplasms / secondary. Cocaine-Related Disorders / complications. Combined Modality Therapy. Fatal Outcome. Heroin Dependence / complications. Humans. Male. Middle Aged. Patient Compliance. Smoking / adverse effects. Substance Abuse, Intravenous / complications. Tomography, X-Ray Computed


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4. Resto VA, Krane JF, Faquin WC, Lin DT: Immunohistochemical distinction of intestinal-type sinonasal adenocarcinoma from metastatic adenocarcinoma of intestinal origin. Ann Otol Rhinol Laryngol; 2006 Jan;115(1):59-64
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical distinction of intestinal-type sinonasal adenocarcinoma from metastatic adenocarcinoma of intestinal origin.
  • OBJECTIVES: Distinction of intestinal-type sinonasal adenocarcinoma (ITAC) from adenocarcinoma of intestinal origin metastatic to the sinonasal cavity may be extremely difficult on histologic grounds alone.
  • We studied the role of cytokeratin (CK) and mucin (MUC) expression in differentiating ITAC, metastatic adenocarcinoma of intestinal origin, and non-intestinal-type sinonasal adenocarcinoma (non-ITAC).
  • METHODS: We stained specimens from 5 cases of ITAC and 4 cases of non-ITAC, along with 4 colonic and 3 duodenal adenocarcinoma controls, with CK7 and CK20, MUC2 and MUC5, neuron-specific enolase (NSE), chromogranin (CHR), and carcinoembryonic antigen (CEA) in order to examine the possible combinations of markers that best aid in the diagnosis of these lesions.
  • [MeSH-major] Adenocarcinoma / metabolism. Colonic Neoplasms / metabolism. Duodenal Neoplasms / metabolism. Keratins / metabolism. Mucins / metabolism. Paranasal Sinus Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Keratin-20. Keratin-7. Male. Middle Aged. Mucin-2. Retrospective Studies

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  • (PMID = 16466101.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 0 / MUC2 protein, human; 0 / Mucin-2; 0 / Mucins; 68238-35-7 / Keratins
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5. O'Rourke AK, Gourin CG, Wade ZK, Hessler RB: Polymorphous low-grade adenocarcinoma of the parotid gland. Ear Nose Throat J; 2006 Oct;85(10):669-71
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  • [Title] Polymorphous low-grade adenocarcinoma of the parotid gland.
  • Polymorphous low-grade adenocarcinoma (PLGA) of the parotid gland is rare.
  • [MeSH-major] Adenocarcinoma / surgery. Neoplasm Recurrence, Local / surgery. Parotid Neoplasms / surgery
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Humans. Male. Middle Aged. Parotid Gland / pathology. Parotid Gland / surgery. Radiotherapy, Adjuvant. Tomography, X-Ray Computed

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  • (PMID = 17124941.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Simone NL, Singh AK, Cowan JE, Soule BP, Carroll PR, Litwin MS: Pretreatment predictors of death from other causes in men with prostate cancer. J Urol; 2008 Dec;180(6):2447-51; discussion 2451-2
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  • RESULTS: Of 13,124 subjects enrolled in CaPSURE 5,070 had clinical T1c-T3a prostatic adenocarcinoma treated with radical prostatectomy (77%) or radiation therapy (23%) and posttreatment followup data.
  • Factors that exclusively predicted death from nonprostate cancer causes included age at diagnosis, having a high school education or less, high clinical risk, smoking at time of diagnosis, concurrent nonprostate malignancy and worse scores on the Short Form-36 Health Survey physical function scale.
  • [MeSH-major] Adenocarcinoma. Prostatic Neoplasms
  • [MeSH-minor] Aged. Cause of Death. Humans. Male. Middle Aged. Prognosis. Risk Factors

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  • (PMID = 18930498.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / ZIA BC011184-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS249810; NLM/ PMC3013289
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7. Storck K, Hadi UM, Simpson R, Ramer M, Brandwein-Gensler M: Sinonasal renal cell-like adenocarcinoma: a report on four patients. Head Neck Pathol; 2008 Jun;2(2):75-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sinonasal renal cell-like adenocarcinoma: a report on four patients.
  • BACKGROUND: We have described an unusual sinonasal neoplasm which is a histological mimic of renal cell carcinoma (RCC) and coined the nosological classification "sinonasal renal cell-like adenocarcinoma" (SRCLA) to describe this unusual entity.
  • All patients are disease-free, based on endoscopy and/or radiography, 2, 4, 5 and 8 years after diagnosis.
  • CONCLUSION: Sinonasal renal cell-like adenocarcinoma is a rare and distinct entity noteworthy in its resemblance to RCC.
  • [MeSH-major] Adenocarcinoma / pathology. Nasal Cavity / pathology. Nasopharyngeal Neoplasms / pathology. Paranasal Sinus Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Kidney Neoplasms / pathology. Male. Middle Aged. Young Adult

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  • (PMID = 20614326.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2807555
  • [Keywords] NOTNLM ; Renal cell carcinoma / Renal cell-like carcinoma / Sinonasal / Vermeer
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8. Chang KH, Song CE, Seo JH, Yeo SW: Solitary metastasis of bronchogenic adenocarcinoma to the internal auditory canal: a case report. J Korean Med Sci; 2009 Dec;24(6):1227-9
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  • [Title] Solitary metastasis of bronchogenic adenocarcinoma to the internal auditory canal: a case report.
  • We report a patient with an isolated metastasis to the internal auditory canal (IAC) of bronchogenic adenocarcinoma.
  • A 58-yr-old man who had received 6-cycle of chemotherapy under diagnosis of non-small cell lung carcinoma (T4N2M0) two years ago was referred to our department with vertigo, right-sided facial paralysis and right-sided hearing loss.
  • A provisional diagnosis of vestibular schwannoma or meningioma involving right IAC was made from magnetic resonance imaging.
  • Histopathological study of the resected lesion showed a poorly differentiated adenocarcinoma compatible with bronchogenic origin.
  • [MeSH-major] Adenocarcinoma / pathology. Ear Neoplasms / secondary. Lung Neoplasms / pathology
  • [MeSH-minor] Fatal Outcome. Humans. Male. Middle Aged

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  • (PMID = 19949690.001).
  • [ISSN] 1598-6357
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2775882
  • [Keywords] NOTNLM ; Adenocarcinoma / Internal Auditory Canal / Lung Neoplasms / Neoplasm Metastasis
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9. Carr S, Anderson C: Metastatic rectal adenocarcinoma in the external auditory canal. J Laryngol Otol; 2009 Mar;123(3):363-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic rectal adenocarcinoma in the external auditory canal.
  • OBJECTIVES: To present a rare case of rectal adenocarcinoma metastasising to the external auditory canal, in a patient in whom computed tomography staging of the abdomen, chest and pelvis was clear for metastatic disease.
  • CONCLUSIONS: Metastatic tumours to the external auditory canal are rare, with rectal adenocarcinoma being one of the rarest.
  • Metastatic tumour should be included in the differential diagnosis of a patient presenting with an ear mass.
  • [MeSH-major] Adenocarcinoma / secondary. Ear Canal. Ear Neoplasms / secondary. Rectal Neoplasms / pathology
  • [MeSH-minor] Humans. Male. Middle Aged. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 18533051.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 7
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10. Baumgartner BJ, Ladd T, Esquivel C: Low-grade adenocarcinoma of the nasal cavity--an unusual presentation: case report and review of the literature. Ear Nose Throat J; 2007 Feb;86(2):97-100
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  • [Title] Low-grade adenocarcinoma of the nasal cavity--an unusual presentation: case report and review of the literature.
  • Low-grade nasal cavity adenocarcinoma is an unusual neoplasm.
  • Most of these tumors arise in patients who are middle-aged or older.
  • We report a case of low-grade nasal cavity adenocarcinoma that was unusual in that it occurred in an adolescent boy and that the presenting symptoms of chronic nasal obstruction and recurrent epistaxis had persisted for 7 years.
  • The occurrence of this uncommon but recognized entity in such a young patient widens the age range of possible patients with this tumor, and a finding of such an extended duration of symptoms should raise clinical suspicion and encourage a thorough investigation in order to make the diagnosis.
  • [MeSH-major] Adenocarcinoma / diagnosis. Nasal Cavity. Nose Neoplasms / diagnosis

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  • (PMID = 17385618.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Kim CW, Rho YS, Cho SJ, Lee CH, Bae WJ: A case of ceruminous adenocarcinoma of the external auditory canal presenting as an aural polyp. Am J Otolaryngol; 2008 May-Jun;29(3):205-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of ceruminous adenocarcinoma of the external auditory canal presenting as an aural polyp.
  • Ceruminous adenocarcinoma is a rare malignant tumor arising from the ceruminous gland of the external auditory canal ceruminous gland.
  • It is important to make an early diagnosis to improve the treatment's outcome.
  • We present the case of a 54-year-old female patient with a 1-year history of feeling blockage in her left ear.
  • Otoscopic examination revealed an aural polyp arising from the cartilaginous ear canal's anterosuperior wall.
  • A wide local excisional biopsy was performed, and the pathologic result was a ceruminous adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Ear Canal. Ear Neoplasms / diagnosis. Polyps / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Middle Aged. Otologic Surgical Procedures / methods. Otoscopy. Temporal Bone / surgery. Tomography, X-Ray Computed

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  • (PMID = 18439958.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Markou K, Karasmanis I, Vlachtsis K, Petridis D, Nikolaou A, Vital V: Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review. Am J Otolaryngol; 2008 Mar-Apr;29(2):142-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review.
  • INTRODUCTION: Primary neoplasms of the external ear canal are rare, and 5% of these tumors are of glandular origin.
  • Ceruminal glands are modified sweat glands of the skin of the external auditory meatus that may give rise to (a) benign tumors such as ceruminous adenoma, pleomorphic adenoma, and syringocystadenoma papilliferum, and (b) malignant tumors such as ceruminous adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma.
  • An alternative theory holds that pleomorphic adenomas may well arise from ectopic salivary tissue present in the external ear canal.
  • In this report, we describe an unusual case of pleomorphic adenoma of the external auditory canal associated with chronic infection of the middle ear.
  • Subsequent biopsy and histologic examination revealed pleomorphic adenoma of the external ear canal, possibly with malignant elements.
  • CONCLUSIONS: Pleomorphic adenoma is an extremely rare tumor arising from the ceruminal glands of the external ear canal.
  • Nonspecific presentation and difficult histologic diagnosis characterize this benign neoplasm.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Ear, External / pathology. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Earache / etiology. Female. Humans. Mastoid / surgery. Middle Aged. Otitis Media / etiology

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  • (PMID = 18314029.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
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13. Aubry K, Sauvage JP, Puyraud S: [Amphicrine adenoma of the middle ear: three cases reports and a review of the literature]. Rev Laryngol Otol Rhinol (Bord); 2006;127(3):145-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Amphicrine adenoma of the middle ear: three cases reports and a review of the literature].
  • Amphicrine adenoma is an extremely rare tumor of the middle ear.
  • MATERIALS AND METHODS: Three cases of middle ear amphicrine tumour were reviewed.
  • RESULTS: During a 10 year period (1986-2006) three cases of middle ear amphicrine tumour were treated at our unit (2 male, 1 female).
  • Differential diagnosis can be difficult and one individual was initially treated as an adenocarcinoma by radiotherapy.
  • CONCLUSION: Historically, differential diagnosis between amphicrine adenoma and adenocarcinoma of the middle ear has been very difficult.
  • [MeSH-major] Adenoma / pathology. Ear Neoplasms / pathology. Ear, Middle / pathology
  • [MeSH-minor] Adult. Carcinoid Tumor / pathology. Carcinoid Tumor / surgery. Female. Humans. Male. Middle Aged

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  • (PMID = 17007186.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 20
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14. Grunstein E, Kacker A: Salivary gland cystadenocarcinoma of the mobile tongue, low-grade papillary adenocarcinoma variant: a case report. Ear Nose Throat J; 2006 Dec;85(12):829-30
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  • [Title] Salivary gland cystadenocarcinoma of the mobile tongue, low-grade papillary adenocarcinoma variant: a case report.
  • [MeSH-major] Cystadenocarcinoma, Papillary / diagnosis. Salivary Gland Neoplasms / diagnosis
  • [MeSH-minor] Female. Humans. Middle Aged. Tongue / pathology

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  • (PMID = 17240709.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Busaba NY, de Oliveira LV, Kieff DL: Correlation between preoperative clinical diagnosis and histopathological findings in patients with rhinosinusitis. Am J Rhinol; 2005 Mar-Apr;19(2):153-7
MedlinePlus Health Information. consumer health - Sinusitis.

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  • [Title] Correlation between preoperative clinical diagnosis and histopathological findings in patients with rhinosinusitis.
  • BACKGROUND: The diagnosis of chronic rhinosinusitis (CRS) or chronic rhinosinusitis with polyposis (CRSP) is typically clinical and based on the combination of medical history, physical examination, and imaging.
  • The recommendation to perform surgery and the type of surgery is tailored to the diagnosis.
  • The objective of this study is to determine the accuracy of preoperative clinical CRS or CRSP diagnosis in patients who underwent endoscopic sinus surgery.
  • METHODS: This is a retrospective review of a case series of 380 consecutive patients who underwent endoscopic sinus surgery for the preoperative clinical diagnosis of CRS or bilateral CRSP.
  • Data regarding symptoms, nasal endoscopy, computed tomography findings, preoperative diagnosis, and postoperative histopathology results were collected.
  • Two of the 180 patients (1.1%) with the preoperative diagnosis of CRS had a different postoperative histopathological diagnosis.
  • The histopathology in both patients showed noncaseating granulomata, leading to a diagnosis of sarcoidosis.
  • Nine of the 200 patients (4.5%) with the preoperative diagnosis of CRSP had a different postoperative histopathological diagnosis.
  • Of these nine patients, five had inverted papilloma (bilaterally in one instance); one had adenocarcinoma; one had squamous-cell carcinoma; one had chronic invasive granulomatous fungal sinusitis; and one had sinonasal sarcoidosis.
  • CONCLUSION: The preoperative clinical diagnosis can be inaccurate in patients with CRS and bilateral CRSP.
  • [MeSH-major] Rhinitis / diagnosis. Sinusitis / diagnosis
  • [MeSH-minor] Adolescent. Aged. Female. Humans. Male. Middle Aged. Nasal Mucosa / pathology. Papilloma, Inverted / diagnosis. Papilloma, Inverted / pathology. Retrospective Studies

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  • (PMID = 15921214.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Yu Y, Zhang R, Dai C: [The study on the en bloc resection of the external auditory canal to treat external auditory canal carcinoma in the early stage]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Apr;23(7):313-5

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  • To improve early diagnosis and the effective surgical management of external auditory canal carcinoma.
  • Eight cases complaint of otalgia or ear pain and 6 cases present with otorrhea.
  • Postoperative pathological diagnosis revealed that 6 cases with adenoid cystic carcinomas, 5 cases of squamous cell carcinomas, 1 case of cerumenal adenocarcinoma.
  • Five cases of squamous cell carcinomas, 1 case of cerumenal adenocarcinoma and 3 cases of adenoid cystic carcinomas received radiotherapy postoperatively.
  • [MeSH-major] Carcinoma / surgery. Ear Neoplasms / surgery. Ear, External / surgery. Otologic Surgical Procedures / methods
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies

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  • (PMID = 19670611.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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17. Doherty JK, Yong M, Maceri D: Endolymphatic sac tumor: a report of 3 cases and discussion of management. Ear Nose Throat J; 2007 Jan;86(1):30-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Ear Neoplasms / diagnosis. Ear Neoplasms / therapy. Endolymphatic Sac
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged

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  • (PMID = 17315832.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Ingram WF, Noone MC, Gillespie MB: Respiratory epithelial adenomatoid hamartoma: a case report. Ear Nose Throat J; 2006 Mar;85(3):190-2
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  • Although READ hamartomas are thought to be rare, awareness of the lesion is important since it may be confused with sinonasal adenocarcinoma, leading to overly aggressive treatment.
  • Therefore, READ hamartoma should be included in the differential diagnosis of a unilateral nasal mass.
  • [MeSH-major] Hamartoma / diagnosis. Hamartoma / pathology. Nose Diseases / diagnosis. Nose Diseases / pathology. Respiratory Mucosa / pathology
  • [MeSH-minor] Diagnosis, Differential. Endoscopy. Humans. Male. Middle Aged. Nasal Cavity / pathology. Nasal Cavity / radiography. Tomography, X-Ray Computed

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  • (PMID = 16615604.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Codreanu CM, Duet M, Hautefort C, Wassef M, Guichard JP, Giraud S, Richard S, Roqueplo AP, Tran Ba Huy P: Endolymphatic sac tumors in von Hippel-Lindau disease: report of three cases. Otol Neurotol; 2010 Jun;31(4):660-4
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  • CONCLUSION: Diagnosis of ELSTs may be difficult especially when the original site of the lesion cannot be clearly identified.
  • [MeSH-major] Adenocarcinoma / pathology. Ear Neoplasms / pathology. Endolymphatic Sac / pathology. von Hippel-Lindau Disease / pathology
  • [MeSH-minor] Adolescent. Adult. Audiometry, Pure-Tone. Female. Genetic Testing. Hearing Loss / genetics. Humans. Middle Aged. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 20351605.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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20. Cohn ML, Elliott DD, El-Naggar AK: Metastatic acinic cell carcinoma in a neurofibroma mistaken for carcinosarcoma. Head Neck; 2005 Jan;27(1):76-80
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  • The resection specimen revealed a spindle cell lesion with metastatic foci of high-grade adenocarcinoma, initially diagnosed as a carcinosarcoma.
  • The bland morphology and S-100-positive expression of the spindle cell lesion confirmed the diagnosis of neurofibroma.
  • CONCLUSION: To our knowledge, this is the first reported case of acinic cell carcinoma metastatic to a neurofibroma, an important entity in the differential diagnosis of biphasic tumors of the head and neck.
  • [MeSH-minor] Diagnosis, Differential. Ear, External / pathology. Humans. Male. Middle Aged. Soft Tissue Neoplasms / pathology. Temporal Bone / pathology

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  • [Copyright] Copyright 2004 Wiley Periodicals, Inc.
  • (PMID = 15565563.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Kim SA, Mathog RH: Acinic cell carcinoma of the parotid gland: a 15-year review limited to a single surgeon at a single institution. Ear Nose Throat J; 2005 Sep;84(9):597-602
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  • For the most part, treatment included either superficial parotidectomy or total parotidectomy with facial nerve preservation; 1 patient with coexisting adenocarcinoma underwent a more radical procedure, and 4 patients underwent adjuvant radiation therapy.
  • [MeSH-major] Carcinoma, Acinar Cell / diagnosis. Carcinoma, Acinar Cell / therapy. Parotid Gland / surgery. Parotid Neoplasms / diagnosis. Parotid Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Prognosis. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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  • (PMID = 16261761.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Huang SF, Chuang WY, Cheng SD, Hsin LJ, Lee LY, Kao HK: A colliding maxillary sinus cancer of adenosquamous carcinoma and small cell neuroendocrine carcinoma--a case report with EGFR copy number analysis. World J Surg Oncol; 2010;8:92
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  • A tumor with squamous cell carcinoma, adenocarcinoma and SNEC co-existence is extremely rare.
  • CASE PRESENTATION: We present a colliding tumor of squamous cell, adenocarcinoma and SNEC in maxillary sinus.
  • The clinical features, diagnosis and EGFR flourescence in situ hybridization (FISH) study are presented.
  • The pathology revealed a malignant tumor composed of squamous cell carcinoma, adenocarcinoma and SNEC components.
  • CONCLUSION: A colliding tumor of squamous cell, adenocarcinoma and neuroendocrine carcinoma in maxillary sinus was aggressive in behavior and the treatment response was poor due to the complexity of tumor.
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Fatal Outcome. Female. Follow-Up Studies. Humans. In Situ Hybridization, Fluorescence. Magnetic Resonance Imaging. Middle Aged

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  • (PMID = 20961443.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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  • [Other-IDs] NLM/ PMC2984401
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23. Park SJ, Wee WR, Lee JH, Kim MK: Primary sebaceous carcinoma of the corneaoscleral limbus with pagetoid recurrence. Korean J Ophthalmol; 2009 Jun;23(2):104-7
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  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Eye Neoplasms / pathology. Limbus Corneae / pathology. Neoplasm Recurrence, Local. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Biological Dressings. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged. Ophthalmologic Surgical Procedures / methods

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  • (PMID = 19568359.001).
  • [ISSN] 2092-9382
  • [Journal-full-title] Korean journal of ophthalmology : KJO
  • [ISO-abbreviation] Korean J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2694285
  • [Keywords] NOTNLM ; Conjunctiva / Limbus / Mitomycin C / Pagetoid recurrence / Sebaceous carcinoma
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24. Tsutsumi T, Nakajima N, Hirose T, Watanabe K: Total-length invasion of the facial nerve by parotid carcinoma ex pleomorphic adenoma. Auris Nasus Larynx; 2009 Oct;36(5):618-22
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  • Total parotid resection with neck dissection was performed, as well as resection of the ear canal, eardrum, ossicles, and transmastoid and translabyrinthine facial nerve, and obliteration using the fascia lata and fatty tissue.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma, Pleomorphic / diagnosis. Facial Nerve / pathology. Parotid Gland. Salivary Gland Neoplasms / diagnosis
  • [MeSH-minor] Facial Bones / radiography. Facial Paralysis / etiology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Radiotherapy, Adjuvant. Tomography, X-Ray Computed

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  • (PMID = 19261405.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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25. Alberty J, Möllers A, Stoll W: [Expert assessment of adenocarcinomas of the nasal cavity and the paranasal sinuses caused by wood dust]. Laryngorhinootologie; 2009 Feb;88(2):106-11
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  • MATERIALS AND METHODS: A retrospective analysis of 43 cases which had been evaluated between March 1994 and February 2007 for an occupational disease #4203, in the Ear-Nose-Throat clinic of the Münster University Hospital, Germany.
  • [MeSH-major] Adenocarcinoma / etiology. Dust. Expert Testimony / legislation & jurisprudence. Nasal Cavity. Nose Neoplasms / etiology. Occupational Diseases / etiology. Occupational Exposure / adverse effects. Paranasal Sinus Neoplasms / etiology. Wood / adverse effects
  • [MeSH-minor] Aged. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / etiology. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery. Postoperative Complications / diagnosis. Postoperative Complications / etiology. Practice Guidelines as Topic. Radiation Injuries / diagnosis. Radiation Injuries / etiology. Radiotherapy, Adjuvant. Retrospective Studies. Workers' Compensation / legislation & jurisprudence

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  • (PMID = 18651374.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Dust
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26. Singh RP, Tullis S, Hatton M, Rubin PA: Orbital metastasis from ovarian carcinoma in a patient with BRCA-2 mutation. Ophthal Plast Reconstr Surg; 2006 Jul-Aug;22(4):298-9
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  • Fine-needle aspiration and lateral orbitotomy were used to obtain tissue for diagnosis.
  • [MeSH-major] Adenocarcinoma / secondary. Genes, BRCA2. Mutation / genetics. Orbital Neoplasms / secondary. Ovarian Neoplasms / genetics. Ovarian Neoplasms / pathology
  • [MeSH-minor] Fatal Outcome. Female. Humans. Hysterectomy. Middle Aged. Ovariectomy. Salpingostomy. Tomography, X-Ray Computed

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  • (PMID = 16855505.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Pietniczka-Załeska M, Dabrowska-Bień J: [Parotid tumors: a two-year experience of Otolaryngology Department at MSS Hospital in Warsaw]. Otolaryngol Pol; 2009 Sep;63(7):43-6

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  • The aim of the study is to present current epidemiological data, most frequent complains, our surgical technique, histopathological diagnosis, complications rate and follow-up.
  • RESULTS: The frequency of incidence of benign tumours was 90% and the most frequent histopathological diagnosis was pleomorphic adenoma (49%) and adenolymphoma (42%).
  • The most frequent complication was sensory deficit about the cheek and ear (35%), temporary facial nerve paresis (5%), hematoma (1%), salivary fistula (1%).
  • [MeSH-major] Adenocarcinoma / epidemiology. Adenocarcinoma / surgery. Parotid Neoplasms / epidemiology. Parotid Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Follow-Up Studies. Hospitals, Special. Humans. Male. Middle Aged. Neoplasm Staging. Oral Surgical Procedures / statistics & numerical data. Poland. Retrospective Studies. Survival Analysis. Treatment Outcome. Young Adult

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  • (PMID = 20564899.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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28. Codreanu C, Tran Ba Huy P: Isolate vertigo crisis revealing an endolymphatic sac tumor. Rom J Morphol Embryol; 2010;51(2):387-9
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  • They are aggressive tumors presenting as low-grade papillary adenocarcinoma, but there are no reports of metastasis in the literature.
  • [MeSH-major] Ear Neoplasms / diagnosis. Endolymphatic Sac / pathology. Vertigo / complications. von Hippel-Lindau Disease / complications
  • [MeSH-minor] Female. Humans. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 20495761.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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29. Schnack-Petersen RS, Orkild H, Werther K: [Peripheral facial paralysis caused by an adenocarcinoma of the middle ear]. Ugeskr Laeger; 2005 Apr 25;167(17):1863-4
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  • [Title] [Peripheral facial paralysis caused by an adenocarcinoma of the middle ear].
  • [MeSH-major] Adenocarcinoma / complications. Ear Neoplasms / complications. Ear, Middle. Facial Paralysis / etiology
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Telencephalon / radiography. Tomography, X-Ray Computed

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  • [CommentIn] Ugeskr Laeger. 2005 May 30;167(22):2428-9; author reply 2429 [15987042.001]
  • (PMID = 15929336.001).
  • [ISSN] 0041-5782
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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30. Johnsen T: [Peripheral facial paralysis in adenocarcinoma of the middle ear]. Ugeskr Laeger; 2005 May 30;167(22):2428-9; author reply 2429
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  • [Title] [Peripheral facial paralysis in adenocarcinoma of the middle ear].
  • [MeSH-major] Adenocarcinoma / complications. Ear Neoplasms / complications. Ear, Middle. Facial Paralysis / etiology

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  • [CommentOn] Ugeskr Laeger. 2005 Apr 25;167(17):1863-4 [15929336.001]
  • (PMID = 15987042.001).
  • [ISSN] 0041-5782
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Comment; Letter
  • [Publication-country] Denmark
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