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Items 1 to 100 of about 122
1. Sameshima S, Tomozawa S, Koketsu S, Okada T, Miyato H, Iijima M, Kojima M, Kaji T: Intramucosal adenocarcinoma of the ileum originated 40 years after ileosigmoidostomy. World J Surg Oncol; 2009;7:41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramucosal adenocarcinoma of the ileum originated 40 years after ileosigmoidostomy.
  • BACKGROUND: Small bowel adenocarcinomas (SBAs) are rare carcinomas.
  • A colonoscopy revealed an irregular mucosal lesion with an unclear margin at the ileum side of the anastomosis.
  • A mucosal biopsy specimen showed adenocarcinoma histopathologically.
  • The resected specimen showed a flat mucosal lesion with a slight depression at the ileum adjacent to the anastomosis.
  • Histological examination revealed a well differentiated intramucosal adenocarcinoma (adenocarcinoma in situ).
  • Immunohistological staining demonstrated the overexpression of p53 protein in the adenocarcinoma.
  • CONCLUSION: Adenocarcinoma of the ileum at such an early stage is a very rare event.
  • In this case, there is a possibility that the ileosigmoidostomy resulted in a back flow of colonic stool to the ileum that caused the carcinogenesis of the small intestine.
  • [MeSH-major] Adenocarcinoma / etiology. Appendicitis / surgery. Colon, Sigmoid / surgery. Ileal Neoplasms / etiology. Ileostomy / adverse effects. Postoperative Complications / etiology

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  • (PMID = 19379525.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2676285
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2. Venizelos I, Tamiolakis D, Petrakis G: Primary combined carcinoid and adenocarcinoma of the ileum associated with transitional carcinoma of the bladder. Single case report. Rev Esp Enferm Dig; 2007 Mar;99(3):145-8
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  • [Title] Primary combined carcinoid and adenocarcinoma of the ileum associated with transitional carcinoma of the bladder. Single case report.
  • Composite neoplasms, carcinoid and adenocarcinoma have been reported to occur in several parts of the body, including the stomach, ampulla of Vater, large bowel, lung, and urinary bladder.
  • Here we report a case of a 74-year-old male with a composite carcinoid-adenocarcinoma of the ileum associated with a transitional cell carcinoma of the bladder.
  • The microscopical examination of the composite tumor showed an admixture of typical carcinoid tumor and moderately a differentiated adenocarcinoma.
  • A review of the literature revealed that this is the first reported case of composite carcinoid-adenocarcinoma of the ileum associated with transitional cell carcinoma of the urinary bladder.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoid Tumor / pathology. Carcinoma, Transitional Cell / pathology. Ileal Neoplasms / pathology. Urinary Bladder Neoplasms / pathology

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  • [ErratumIn] Rev Esp Enferm Dig. 2007 Nov;99(11):682. Venizelos, I D [corrected to Venizelos, I]; Lambropoulou, M [removed]; Constantinidis, T [removed]; Alexiadis, G [removed]; Papadopoulos, N [removed]
  • (PMID = 17516827.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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3. Beltrán MA, Barría C, Contreras MA, Wilson CS, Cruces KS: [Adenocarcinoma and intestinal duplication of the ileum. Report of one case]. Rev Med Chil; 2009 Oct;137(10):1341-5
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  • [Title] [Adenocarcinoma and intestinal duplication of the ileum. Report of one case].
  • [Transliterated title] Adenocarcinoma en duplicación intestinal del íleon: Caso clínico.
  • Computed abdominal tomography demonstrated small bowel loops surrounding a tubular cystic structure and peritoneal free fluid.
  • The surgical exploration revealed multiple malignant implants covering the visceral and parietal peritoneum and infiltrating completely the omentum.
  • The histopathology of the cystic wall was compatible with the architecture of intestinal wall extensively infiltrated by a moderately differentiated mucinous adenocarcinoma; a mucosal lining in parts atrophic and in parts infiltrated or replaced by adenocarcinoma was observed.
  • [MeSH-major] Adenocarcinoma / pathology. Ileal Neoplasms / pathology. Ileum / abnormalities

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  • (PMID = 20011941.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Chile
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4. Tirkes AT, Duerinckx AJ: Adenocarcinoma of the ileum in Crohn disease. Abdom Imaging; 2005 Nov-Dec;30(6):671-3
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  • [Title] Adenocarcinoma of the ileum in Crohn disease.
  • Small bowel adenocarcinoma develops in 1.5% of patients who have longstanding Crohn disease and is very rarely diagnosed preoperatively because of its rarity, overlapping imaging features, and lack of reported cases.
  • [MeSH-major] Adenocarcinoma / radiography. Crohn Disease / complications. Ileal Diseases / radiography

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  • (PMID = 15891804.001).
  • [ISSN] 0942-8925
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Cioffi U, De Simone M, Ferrero S, Ciulla MM, Lemos A, Avesani EC: Synchronous adenocarcinoma and carcinoid tumor of the terminal ileum in a Crohn's disease patient. BMC Cancer; 2005;5:157
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  • [Title] Synchronous adenocarcinoma and carcinoid tumor of the terminal ileum in a Crohn's disease patient.
  • BACKGROUND: Several malignancies have been described in association with inflammatory bowel diseases, the most common being adenocarcinoma.
  • Carcinoid tumor and Crohn disease has also been previously reported, however the coexistence of both neoplasms is quite rare and the clinical diagnosis is very difficult.
  • Laparotomy showed a stricturing lesion in the last 6 cm of the terminal ileum with proximal dilation.
  • Only the histology of the resected surgical specimen proved the presence of a mixed adenocarcinoid tumor involving the terminal ileum.
  • [MeSH-major] Adenocarcinoma / complications. Carcinoid Tumor / complications. Crohn Disease / complications. Ileal Neoplasms / complications. Neoplasms, Second Primary / diagnosis
  • [MeSH-minor] Chromogranin A. Chromogranins / metabolism. Female. Humans. Ileum / pathology. Immunohistochemistry. Middle Aged


6. Toyomasu Y, Tsutsumi S, Yamaguchi S, Mochiki E, Asao T, Kuwano H: Primary mucinous adenocarcinoma of the ileum. Int Surg; 2010 Jan-Mar;95(1):60-2
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  • [Title] Primary mucinous adenocarcinoma of the ileum.
  • A laparotomy was performed on a 67-year-old woman with a provisional diagnosis of intestinal obstruction from a primary small bowel carcinoma.
  • A pathological examination showed a mucinous adenocarcinoma of the ileum, with no regional lymph node metastases.
  • Primary small bowel adenocarcinoma is rare in all malignant gastrointestinal neoplasms, and very few cases of the ileal mucinous adenocarcinoma have been reported.
  • We performed a radical operation for the ileal mucinous adenocarcinoma, and long-term survival was obtained.
  • This case suggests that aggressive surgical treatment for an advanced stage of small bowel cancer leads to long-term survival.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Ileal Neoplasms / surgery
  • [MeSH-minor] Aged. Cecal Neoplasms / pathology. Digestive System Surgical Procedures. Fatal Outcome. Female. Humans. Intestinal Obstruction / etiology. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Peritoneal Neoplasms / pathology. Time Factors

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  • (PMID = 20480843.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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7. Ueda Y, Suzuki T, Jun Q, Higuchi Y, Maruyama T, Kondoh N, Nojima M, Yamamoto S, Yamamoto H, Kokura K, Shincho M, Hirota S, Shima H: [An adenocarcinoma arising from the urinary bladder 37 years after bladder augmentation using the ileum]. Hinyokika Kiyo; 2009 Mar;55(3):145-8
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  • [Title] [An adenocarcinoma arising from the urinary bladder 37 years after bladder augmentation using the ileum].
  • A 57-year-old man had undergone right nephrectomy at 10 years of age and bladder augmentation using the ileum at 20 years for treatment of urinary tract tuberculosis.
  • Histopathological examination of the specimen revealed a well differentiated adenocarcinoma.
  • Histopathological examination revealed a well differentiated adenocarcinoma infiltrating into the muscle layer (pT2a).
  • This is the 19th case of adenocarcinoma following bladder augmentation using the ileum reported in the Japanese literature.
  • [MeSH-major] Adenocarcinoma / etiology. Urinary Bladder / surgery. Urinary Bladder Neoplasms / etiology
  • [MeSH-minor] Humans. Ileum / surgery. Male. Middle Aged. Postoperative Complications. Reconstructive Surgical Procedures / adverse effects. Time Factors

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  • (PMID = 19378826.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 11
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8. Sheikh SS, Al-Khatti AA, Amr SS: Metachronus malignant rhabdoid tumor of the ileum and adenocarcinoma of lung: a unique case report. Ann Diagn Pathol; 2008 Feb;12(1):57-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metachronus malignant rhabdoid tumor of the ileum and adenocarcinoma of lung: a unique case report.
  • Malignant extrarenal rhabdoid tumors had been described in a variety of anatomic locations including gastrointestinal tract.
  • Carcinomas of small intestine are quite uncommon neoplasms, and those with rhabdoid differentiation are exceedingly rare.
  • These poorly differentiated tumors pose a great deal of difficulty in diagnosis as well as in deciding whether they are primary or metastatic in origin because malignant rhabdoid tumors or carcinomas with rhabdoid differentiation of other sites can metastasize to the small intestine.
  • Herein, we report a 52-year-old patient with primary small bowel malignant rhabdoid tumor, who was completely disease-free after the initial presentation and management.
  • Five years later, he was found to have a lung mass proved to be adenocarcinoma, exhibiting focal giant cell differentiation without rhabdoid features.
  • [MeSH-major] Adenocarcinoma / pathology. Ileal Neoplasms / pathology. Lung Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Rhabdoid Tumor / pathology
  • [MeSH-minor] Disease-Free Survival. Humans. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 18164418.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Nacchiero MC, Verderosa G, Muscatiello N, Della Valle N, Diterlizzi F, Tricarico F, Di Gioia G, Melino R, Panella C, Ierardi E: Advanced adenocarcinoma of terminal ileum: an unusual neoplasm revealed by an unusual diagnostic tool. Acta Biomed; 2010 Dec;81(3):230-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Advanced adenocarcinoma of terminal ileum: an unusual neoplasm revealed by an unusual diagnostic tool.
  • BACKGROUND AND AIM: Terminal ileum adenocarcinoma is a rare tumour.
  • Since contrast enhanced ultrasonography has been recently used to study bowel alterations in the course of neoplastic or inflammatory disorders, we report here a case of a rare tumour (terminal ileum poorly differentiated adenocarcinoma) in which the investigation played a pivotal role to obtain a defined diagnosis.
  • CONCLUSIONS: At present it is too speculative to emphasize contrast enhanced ultrasonography as usefulness tool in the diagnosis of terminal ileum tumors.
  • [MeSH-major] Adenocarcinoma / ultrasonography. Ileal Neoplasms / ultrasonography

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  • (PMID = 22530462.001).
  • [ISSN] 0392-4203
  • [Journal-full-title] Acta bio-medica : Atenei Parmensis
  • [ISO-abbreviation] Acta Biomed
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Phospholipids; 0 / contrast agent BR1; WS7LR3I1D6 / Sulfur Hexafluoride
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10. Farrell S, Gray SB, Best BG: Mucusuria--an unusual manifestation of ileal adenocarcinoma: a case report and review of the literature. Int Surg; 2005 Apr-Jun;90(2):85-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucusuria--an unusual manifestation of ileal adenocarcinoma: a case report and review of the literature.
  • Primary adenocarcinoma of the ileum is an uncommon gastrointestinal malignancy, the symptoms of which are often insidious in onset.
  • This case history highlights the previously unreported finding of ileal adenocarcinoma presenting with mucusuria, caused by local invasion of the bladder in a 44-year-old male.
  • A review of the literature is included to highlight the incidence, risk factors, clinical presentation, investigation, and current management of adenocarcinoma of the small bowel.
  • [MeSH-major] Adenocarcinoma / secondary. Ileal Neoplasms / pathology. Intestinal Fistula / diagnosis. Urinary Bladder Fistula / diagnosis. Urinary Bladder Neoplasms / secondary
  • [MeSH-minor] Adult. Humans. Male. Mucus. Neoplasm Invasiveness. Urinalysis

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  • (PMID = 16119711.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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11. Ruiz-Tovar J, Martínez-Molina E, Morales V, Sanjuanbenito A: [Primary small bowel adenocarcinoma]. Cir Esp; 2009 Jun;85(6):354-9
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  • [Title] [Primary small bowel adenocarcinoma].
  • [Transliterated title] Adenocarcinoma primario de intestino delgado.
  • INTRODUCTION: Primary small bowel adenocarcinoma is an uncommon tumour, with non-specific symptoms that cause a delay in the diagnosis and consequently a worse outcome for the patient.
  • MATERIAL AND METHOD: We performed a retrospective study of our experience with 17 patients diagnosed with primary small bowel adenocarcinoma, excluding all the cases suggesting secondary involvement of the small bowel from an adenocarcinoma in other locations.
  • Tumour location was duodenum (8 cases), jejunum (5) and ileum (4).
  • CONCLUSIONS: Curative treatment consists of small bowel resection.
  • [MeSH-major] Adenocarcinoma. Duodenal Neoplasms. Ileal Neoplasms. Jejunal Neoplasms

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  • (PMID = 19344893.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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12. Sasaki Y, Natsuizaka M, Takano M, Suzuki M, Tsuyuguchi M, Nagasako T, Kawamura N, Kudo M, Tsuda I, Meguro J: [A case of primary adenocarcinoma of small intestine with multiple liver metastases successfully treated with mFOLFOX6]. Gan To Kagaku Ryoho; 2009 Nov;36(11):1927-9
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  • [Title] [A case of primary adenocarcinoma of small intestine with multiple liver metastases successfully treated with mFOLFOX6].
  • Colonoscopy showed a tumor of Bauhin's valve and terminal ileum.
  • Biopsy of the tumor was performed and pathological examination revealed adenocarcinoma.
  • Ileocecal resection was performed because of severe stenosis of the terminal ileum.
  • Histopathological examination revealed moderately-differentiated adenocarcinoma of Bauhin's valve and the terminal ileum, and no adenocarcinoma was found in the cecum and ascending colon.
  • He was diagnosed with primary adenocarcinoma of the ileum with multiple liver metastases.
  • Effectiveness of mFOLFOX6 for primary adenocarcinoma of small intestine is suggested.
  • [MeSH-major] Adenocarcinoma / pathology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Ileal Neoplasms / pathology. Liver Neoplasms / drug therapy. Liver Neoplasms / secondary

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  • (PMID = 19920403.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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13. Napolitano L, de Nicola P, Di Bartolomeo N, Aceto L, Liddo G, Angelucci D, Innocenti P: [A case of perforated small bowel adenocarcinoma as first symptom of Crohn's disease]. G Chir; 2005 May;26(5):212-4
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  • [Title] [A case of perforated small bowel adenocarcinoma as first symptom of Crohn's disease].
  • [Transliterated title] Adenocarcinoma perforato del piccolo intestino come prima evidente manifestazione del morbo di Crohn: case report.
  • A case of perforated small bowel adenocarcinoma presenting as first symptom of Crohn's disease is reported in a 53 years old male patient with abdominal pain and alteration of bowel habits.
  • A narrowing perforated neoplasia in terminal ileum was discovered at laparotomy.
  • [MeSH-major] Adenocarcinoma / complications. Crohn Disease / diagnosis. Ileal Neoplasms / complications. Intestinal Perforation / etiology

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  • (PMID = 16184705.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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14. Juaneda Castell B, Angerri Feu O, Caffaratti SJ, Garat Barredo JM, Villavicencio Mavrich H: [Adenocarcinoma in a ileal conduit after cystectomy for bladder exstrophy]. Actas Urol Esp; 2008 Oct;32(9):937-9; discussion 940
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  • [Title] [Adenocarcinoma in a ileal conduit after cystectomy for bladder exstrophy].
  • [Transliterated title] Adenocarcinoma en conducto ileal después de cistectomía por extrofia vesical.
  • [MeSH-major] Adenocarcinoma. Bladder Exstrophy / surgery. Cystectomy. Ileal Neoplasms. Ileum / surgery. Postoperative Complications. Urinary Diversion

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  • (PMID = 19048682.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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15. Lutz JC, El-Bouihi M, Vidal N, Fricain JC, Robert M, Deminière C, Zwetyenga N: Mandibular metastases from an ileum stromal tumor. Rev Stomatol Chir Maxillofac; 2008 Dec;109(6):399-402
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  • [Title] Mandibular metastases from an ileum stromal tumor.
  • Jaw metastases from the gastrointestinal (GI) tract usually evolve from adenocarcinoma of the esophagus, colon, and rectum.
  • These tumors are thought to arise from Cajal cells in GI tract walls, essential for intestine motor function.
  • The small intestine harbors only 30% of GIST.
  • The purpose of this study was to report the first case of mandibular metastases arising from a stromal tumor of the ileum.
  • A complete CT-Scan analysis revealed an ileum tumor.
  • Biopsies and immunochemistry proved an ileum stromal tumor.
  • All tumoral cells expressed the C-Kit in the ileum and the mandible.
  • The patient was treated with imatinib but died 11 months after the diagnosis.
  • DISCUSSION: The prevalence of GIST is low but the true incidence may be higher because of under-diagnosis.
  • To our knowledge, this is the first well-documented case report of jaw metastasis from ileum GIST.
  • GIST should be included in the differential diagnosis of intramandibular tumor in patients with prior or current non-oral malignancy.

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  • (PMID = 19010506.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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16. Van Kerkhóve F, Coenegrachts K, Steyaert L, Van Den Berghe I, Casselman JW: Collision tumor in the ileum: a rare combination of an adenocarcinoma and small cell neuroendocrine tumor. JBR-BTR; 2006 Sep-Oct;89(5):258-60
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  • [Title] Collision tumor in the ileum: a rare combination of an adenocarcinoma and small cell neuroendocrine tumor.
  • We present a case of a rare small bowel tumor.
  • Ultrasound examination discovered an inhomogeneous vascularised mass originating from a small bowel loop, mesenteric enlarged lymph nodes and a nodule in the liver.
  • Pathology revealed a rare ileal collision tumor consisting of an adenocarcinoma and a small cell neuroendocrine tumor with peritoneal metastasis of neuroendocrine origin and coincidental benign lesions on both ovaries.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma, Villous / diagnosis. Adenomatous Polyps / diagnosis. Carcinoma, Small Cell / diagnosis. Ileal Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Tomography, X-Ray Computed. Ultrasonography
  • [MeSH-minor] Adenofibroma / diagnosis. Adenofibroma / pathology. Adenofibroma / surgery. Aged. Cystadenoma / diagnosis. Cystadenoma / pathology. Cystadenoma / surgery. Female. Fibroma / diagnosis. Fibroma / pathology. Fibroma / surgery. Humans. Ileum / pathology. Ileum / surgery. Intestinal Mucosa / pathology. Intestinal Mucosa / surgery. Liver / pathology. Liver / surgery. Lymphatic Metastasis / pathology. Mesentery / pathology. Mesentery / surgery. Omentum / pathology. Omentum / surgery. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / pathology. Ovarian Neoplasms / surgery. Ovariectomy. Ovary / pathology. Peritoneum / pathology. Peritoneum / surgery

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  • (PMID = 17147014.001).
  • [ISSN] 0302-7430
  • [Journal-full-title] JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)
  • [ISO-abbreviation] JBR-BTR
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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17. Ugurlu MM, Asoglu O, Potter DD, Barnes SA, Harmsen WS, Donohue JH: Adenocarcinomas of the jejunum and ileum: a 25-year experience. J Gastrointest Surg; 2005 Nov;9(8):1182-8
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  • [Title] Adenocarcinomas of the jejunum and ileum: a 25-year experience.
  • Adenocarcinomas of the jejunum and ileum are rare gastrointestinal malignancies.
  • Because few large published experiences exist, we reviewed patients with jejunal and ileal adenocarcinoma treated at our institution over the last 25 years.
  • Between January 1976 and December 2001, 77 patients had an operation for a jejunal or ileal adenocarcinoma.
  • Fifty-two of the adenocarcinomas (67%) occurred in the jejunum and 25 occurred in the ileum (33%).
  • One (1%) patient had stage I, 18 (23%) stage II, 19 (25%) stage III, and 39 (51%) stage IV adenocarcinoma at diagnosis.
  • Most patients with adenocarcinoma of the jejunum or ileum present with advanced disease.
  • [MeSH-major] Adenocarcinoma / surgery. Ileal Neoplasms / surgery. Jejunal Neoplasms / surgery
  • [MeSH-minor] Combined Modality Therapy. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Palliative Care. Proportional Hazards Models. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 16269390.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Hori K, Sudo A, Wakabayashi H, Matsumine A, Kusuzaki K, Uchida A: Asymptomatic disseminated carcinomatosis of bone marrow presenting as hyperphosphatasia: report of a case. Acta Gastroenterol Belg; 2008 Apr-Jun;71(2):271-4
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  • Bone scintigraphy showed a so-called super bone scan and a needle biopsy from the ileum showed adenocarcinoma cells.
  • From the bone scan and biopsy, we established the diagnosis of disseminated carcinomatosis of the bone marrow.
  • [MeSH-minor] Aged. Biopsy, Needle. Diagnosis, Differential. Disease Progression. Female. Follow-Up Studies. Humans

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  • (PMID = 18720942.001).
  • [ISSN] 1784-3227
  • [Journal-full-title] Acta gastro-enterologica Belgica
  • [ISO-abbreviation] Acta Gastroenterol. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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19. Palascak-Juif V, Bouvier AM, Cosnes J, Flourié B, Bouché O, Cadiot G, Lémann M, Bonaz B, Denet C, Marteau P, Gambiez L, Beaugerie L, Faivre J, Carbonnel F: Small bowel adenocarcinoma in patients with Crohn's disease compared with small bowel adenocarcinoma de novo. Inflamm Bowel Dis; 2005 Sep;11(9):828-32
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  • [Title] Small bowel adenocarcinoma in patients with Crohn's disease compared with small bowel adenocarcinoma de novo.
  • BACKGROUND: Data concerning small bowel adenocarcinoma (SBA) in Crohn's disease (CD) come from case reports and small retrospective series.
  • The aim of this study was to further describe SBA in patients with CD and compare it with SBA de novo.
  • METHODS: Twenty patients with CD with SBA recruited in French university hospitals were studied and compared with 40 patients with SBA de novo recruited from a population-based registry.
  • SBA occurred after a median time of 15 years of CD and was located within the inflamed areas of the ileum (n=19) or jejunum (n=1), whereas in patients with SBA de novo, it was distributed all along the small intestine.
  • Median age at diagnosis of SBA was 47 years (range, 33-72 yr) in patients with CD and 68 years (range, 41-95 yr) in those with SBA de novo.
  • Diagnosis was made preoperatively in 1/20 patients with CD and 22/40 patients with SBA de novo.
  • Signet ring cells were found in 35% of patients with CD but not in patients with SBA de novo.
  • CONCLUSIONS: SBA in CD is different from SBA de novo.
  • [MeSH-major] Adenocarcinoma / pathology. Crohn Disease / complications. Ileal Neoplasms / pathology

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  • (PMID = 16116317.001).
  • [ISSN] 1078-0998
  • [Journal-full-title] Inflammatory bowel diseases
  • [ISO-abbreviation] Inflamm. Bowel Dis.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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20. Reddy VB, Aslanian H, Suh N, Longo WE: Asymptomatic ileal adenocarcinoma in the setting of undiagnosed Crohn's disease. World J Gastroenterol; 2008 Aug 7;14(29):4690-3
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  • [Title] Asymptomatic ileal adenocarcinoma in the setting of undiagnosed Crohn's disease.
  • A 53-year old previously healthy male underwent a screening colonoscopy for detection of a potential colorectal neoplasm.
  • The terminal ileum was intubated and a mass was noted.
  • The biopsy of the ileal mass was consistent with an adenocarcinoma arising from the terminal ileum.
  • The patient underwent exploratory laparotomy and a right hemicolectomy with a 30 cm section of terminal ileum in continuity.
  • Findings were consistent with ileal adenocarcinoma in the setting of Crohn's disease.
  • The pathology was stage 1 adenocarcinoma.
  • This is a unique case in that on a screening colonoscopy, a favorable ileal adenocarcinoma was discovered in the setting of asymptomatic, undiagnosed ileal Crohn's disease in a patient whose father had Crohn's disease diagnosed postmortem.
  • [MeSH-major] Adenocarcinoma / diagnosis. Crohn Disease / diagnosis. Ileal Neoplasms / diagnosis

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  • (PMID = 18698685.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2738795
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21. Hosono S, Ohira M, Maeda K, Muguruma K, Nishihara T, Inoue T, Yashiro M, Hirakawa K: Synchronous adenocarcinomas of the ileum and transverse colon detected by capsule endoscopy: report of a case. Surg Today; 2006;36(7):663-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous adenocarcinomas of the ileum and transverse colon detected by capsule endoscopy: report of a case.
  • Neither gastrointestinal endoscopy nor computed tomography showed by abnormal findings; however, a capsule endoscopy, performed to detect obscure gastrointestinal bleeding, revealed a tumor in the ileum.
  • On exploration, tumors were identified in the ileum and the transverse colon.
  • Thus, we resected the ileum and transverse colon with regional lymph node dissection.
  • Histologic sections from both the ileum and colon revealed moderately differentiated adenocarcinomas with no lymph node metastasis.
  • [MeSH-major] Adenocarcinoma / pathology. Capsule Endoscopy. Colonic Neoplasms / pathology. Ileal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 16794807.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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22. Norris WE, Perry JL, Moawad FJ, Horwhat JD: An unusual presentation of metastatic esophageal adenocarcinoma presenting as thigh pain. J Gastrointestin Liver Dis; 2009 Sep;18(3):371-4
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  • [Title] An unusual presentation of metastatic esophageal adenocarcinoma presenting as thigh pain.
  • The association between esophageal adenocarcinoma and distant skeletal muscle metastasis is extremely rare.
  • Computerized axial tomography (CT) scan demonstrated a 10 cm by 8 cm by 12 cm intra-pelvic mass involving the right iliacus muscle with central destruction of the right mid-ileum.
  • Endoscopic biopsy showed poorly differentiated adenocarcinoma.
  • Final diagnosis was primary esophageal adenocarcinoma with distant metastasis to the right ileum and iliacus muscle.
  • We review distinctions between esophageal adenocarcinoma and adenocarcinoma of the gastroesophageal junction.
  • [MeSH-major] Adenocarcinoma / pathology. Esophageal Neoplasms / pathology. Muscle, Skeletal / pathology. Pain / etiology

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  • (PMID = 19795036.001).
  • [ISSN] 1841-8724
  • [Journal-full-title] Journal of gastrointestinal and liver diseases : JGLD
  • [ISO-abbreviation] J Gastrointestin Liver Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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23. Beltran MA, Cruces KS: Primary tumors of jejunum and ileum as a cause of intestinal obstruction: a case control study. Int J Surg; 2007 Jun;5(3):183-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary tumors of jejunum and ileum as a cause of intestinal obstruction: a case control study.
  • BACKGROUND: Small-bowel tumors are rare and account for 1-2% of all gastrointestinal neoplasms.
  • Most of these tumors are found at surgery indicated for other diagnosis or intestinal obstruction.
  • METHODS: We reviewed 17 patients operated on for intestinal obstruction secondary to benign and malignant primary tumors of jejunum and ileum at our institution the last 10 years.
  • Most tumors (65%) were located in the ileum.
  • Mean survival for patients with malignant tumors was 19.5+/-13 months, and for patients with benign tumors 72+/-20 months (p<0.05).
  • [MeSH-minor] Abdomen, Acute / etiology. Adenocarcinoma / complications. Adult. Aged. Case-Control Studies. Female. Gastrointestinal Stromal Tumors / complications. Gastrointestinal Stromal Tumors / pathology. Humans. Leiomyoma / complications. Logistic Models. Lymphoma / complications. Lymphoma / pathology. Male. Middle Aged. Neoplasm Staging. Sarcoma / complications

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  • (PMID = 17509501.001).
  • [ISSN] 1743-9159
  • [Journal-full-title] International journal of surgery (London, England)
  • [ISO-abbreviation] Int J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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24. Sammartino P, Sibio S, Di Giorgio A, Caronna R, Viscido A, Zippi M, Biacchi D, Accarpio F, Mingazzini P, Caprilli R: Two synchronous adenocarcinomas of the small bowel in a patient with undiagnosed Crohn's disease of the terminal ileum. Int J Colorectal Dis; 2006 May;21(4):388-91
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  • [Title] Two synchronous adenocarcinomas of the small bowel in a patient with undiagnosed Crohn's disease of the terminal ileum.
  • A small but significant excess of deaths for tumors of the digestive system has been described in Crohn's disease.
  • In a study analyzing all cancers of the small intestine within a defined population, Crohn's disease was the major underlying factor for cancer of the small intestine.
  • Areas of the small intestine containing strictures are unusually prone to malignant transformation.
  • We report the rare case of a patient in whom surgery for intestinal occlusion disclosed Crohn's disease of the distal ileum complicated by two adenocarcinomas arising within distinct areas of the inflamed bowel.
  • [MeSH-major] Adenocarcinoma / pathology. Crohn Disease / diagnosis. Ileal Neoplasms / pathology

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  • (PMID = 16059693.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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25. Cervantes-Solís C, Jiménez-González A, Zamora-Nava LE, Torre-Delgadillo A: [Thickening of the colon and terminal ileum documented with computer tomography and its correlation with colonoscopic findings at a third-level hospital]. Rev Gastroenterol Mex; 2010;75(2):158-64
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  • [Title] [Thickening of the colon and terminal ileum documented with computer tomography and its correlation with colonoscopic findings at a third-level hospital].
  • [Transliterated title] Engrosamiento colónico y de íleon terminal documentado por tomografía computarizada y su correlación con hallazgos colonoscópicos en un hospital de tercer nivel.
  • BACKGROUND: Tomographic finding of thickening of colon and terminal ileum and its correlation with colonoscopic findings has been poorly studied.
  • OBJECTIVE: To determine if a relationship exists between colonic wall or terminal ileum thickening documented by computed tomography with abnormal colonoscopic findings and colon cancer.
  • METHODS: Retrospective study of radiology database of a tertiary hospital identifying patients with report of thickening of terminal ileum or colon and have colonoscopy performed.
  • The most common colonoscopic finding was colorectal tumor probably malignant in 7 (29.2%) patients, but adenocarcinoma was reported in 8 (33.3%) patients.
  • There was statistical significant correlation between weight loss, melena, anemia, constipation, diarrhea, and hematochezia with diagnosis of cancer (p < 0.01).
  • [MeSH-major] Colon / pathology. Colon / radiography. Colonic Neoplasms / diagnosis. Colonoscopy. Ileum / pathology. Ileum / radiography. Tomography, X-Ray Computed

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  • (PMID = 20615783.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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26. Yamaguchi H, Ishimaru M, Suzuki H, Yamashita H, Hatanaka K, Uekusa T, Nagawa H: Isolated abdominal wound recurrence after lymph-node dissection for appendiceal adenocarcinoma. Am J Surg; 2010 Jan;199(1):e7-9

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  • [Title] Isolated abdominal wound recurrence after lymph-node dissection for appendiceal adenocarcinoma.
  • Postoperative histology revealed a moderately differentiated adenocarcinoma in the appendix that invaded the submucosa along with lymphatic involvement.
  • Three of the 30 resected lymph nodes were found to have adenocarcinoma metastasis.
  • A complete excision of the tumor and the invaded portion of the ileum was performed.
  • [MeSH-major] Abdominal Wall / pathology. Adenocarcinoma / secondary. Adenocarcinoma / surgery. Appendiceal Neoplasms / surgery. Lymph Nodes / surgery. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Abdominal Pain / diagnosis. Abdominal Pain / etiology. Appendectomy / methods. Cicatrix / pathology. Follow-Up Studies. Humans. Immunohistochemistry. Lymph Node Excision / methods. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Reoperation. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19837396.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Sato Y, Tanaka S, Ko Y, Okuda T, Tamura F, Fujimi A, Doi T, Kanisawa Y, Ohta H: Adenocarcinoma of Meckel's diverticulum diagnosed by capsule endoscopy and single-balloon enteroscopy. Clin J Gastroenterol; 2009 Dec;2(6):388-93

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  • [Title] Adenocarcinoma of Meckel's diverticulum diagnosed by capsule endoscopy and single-balloon enteroscopy.
  • A case of adenocarcinoma arising in Meckel's diverticulum in a 58-year-old man is reported.
  • Capsule endoscopy (CE) showed tumorous lesion in the distal ileum.
  • Furthermore, biopsy specimen obtained from the lesion revealed it as adenocarcinoma.
  • At laparotomy, we found the tumor at the blind end of the diverticulum and enlarged lymph node about 7 cm in diameter in the small intestinal mesentery.
  • Segmental resection of the ileum, including the tumor-bearing diverticulum, was performed along with regional lymph node dissection.
  • Although neoplasm in Meckel's diverticulum is difficult to diagnose preoperatively, the combination of CE and SBE was useful.
  • Based on our search, this is thought to be the first case of neoplasm in Meckel's diverticulum diagnosed endoscopically.

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  • (PMID = 26192792.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Capsule endoscopy / Meckel’s diverticulum / Single-balloon enteroscopy
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28. Babu MS, Raza M: Adenocarcinoma in an ileal duplication. J Assoc Physicians India; 2008 Feb;56:119-20
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  • [Title] Adenocarcinoma in an ileal duplication.
  • To our knowledge, since 1884, there have been only 14 reported cases of ileal duplications in adults of which 3 patients had developed malignancy in the duplicated ileum.
  • [MeSH-major] Adenocarcinoma / diagnosis. Ileal Neoplasms / diagnosis. Ileum / abnormalities

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  • (PMID = 18472514.001).
  • [ISSN] 0004-5772
  • [Journal-full-title] The Journal of the Association of Physicians of India
  • [ISO-abbreviation] J Assoc Physicians India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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29. Yoneyama T, Okamoto A, Imai A, Ishimura H, Hagisawa S, Iwabuchi I, Koie T, Yamato T, Ohyama C: [Adenocarcinoma of the ileal segment 40 years after ileocystoplasty: a case report]. Hinyokika Kiyo; 2007 Aug;53(8):589-91
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  • [Title] [Adenocarcinoma of the ileal segment 40 years after ileocystoplasty: a case report].
  • We reported a case of ileal segment adenocarcinoma arising in the augmented bladder 40 years after the operation.
  • The pathological diagnosis was poorly differentiated adenocarcinoma in the ileal segment.
  • [MeSH-major] Adenocarcinoma / etiology. Postoperative Complications. Urinary Bladder / surgery. Urinary Bladder Neoplasms / etiology
  • [MeSH-minor] Anastomosis, Surgical. Humans. Ileum / surgery. Lymph Node Excision. Male. Middle Aged. Time Factors

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  • (PMID = 17874554.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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30. Ota H, Yamazaki K, Endoh W, Hojo S, Fukunaga H, Yoshioka S, Okada Y, Okamoto S, Ueda N, Maeura Y: Adenocarcinoma arising below an ileoanal anastomosis after restorative proctocolectomy for ulcerative colitis: report of a case. Surg Today; 2007;37(7):596-9
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  • [Title] Adenocarcinoma arising below an ileoanal anastomosis after restorative proctocolectomy for ulcerative colitis: report of a case.
  • We report a case of adenocarcinoma developing in remnant rectal mucosa below a hand-sewn ileal pouch-anal anastomosis (IPAA) after restorative proctocolectomy for ulcerative colitis (UC).
  • About 7 years later, a follow-up endoscopy showed a flat elevated malignant lesion, 2 cm in diameter, below the ileoanal anastomosis.
  • Histopathological examination of the resected specimen confirmed the presence of a well-differentiated adenocarcinoma but there were no metastatic lymph nodes.
  • [MeSH-major] Adenocarcinoma, Mucinous / etiology. Anus Neoplasms / etiology. Colitis, Ulcerative / complications. Ileum / surgery. Proctocolectomy, Restorative / adverse effects. Rectum / surgery

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  • (PMID = 17593481.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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31. Dvorak K, Watts GS, Ramsey L, Holubec H, Payne CM, Bernstein C, Jenkins GJ, Sampliner RE, Prasad A, Garewal HS, Bernstein H: Expression of bile acid transporting proteins in Barrett's esophagus and esophageal adenocarcinoma. Am J Gastroenterol; 2009 Feb;104(2):302-9
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  • [Title] Expression of bile acid transporting proteins in Barrett's esophagus and esophageal adenocarcinoma.
  • In contrast to the normal squamous epithelium, enterocytes of the distal ileum are adapted to transport bile acids from the intestinal lumen.
  • Our major goal was to evaluate the expression of bile acid transporters in normal squamous epithelium, BE with different grades of dysplasia, and esophageal adenocarcinoma (EAC).

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  • (PMID = 19174784.001).
  • [ISSN] 1572-0241
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA023074; United States / NIEHS NIH HHS / ES / P30 ES006694; United States / NCI NIH HHS / CA / P50 CA095060
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carrier Proteins; 0 / Membrane Glycoproteins; 0 / Multidrug Resistance-Associated Proteins; 0 / Organic Anion Transporters, Sodium-Dependent; 0 / RNA, Messenger; 0 / Symporters; 0 / bile acid binding proteins; 0 / multidrug resistance-associated protein 3; 145420-23-1 / sodium-bile acid cotransporter
  • [Other-IDs] NLM/ NIHMS693533; NLM/ PMC4450811
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32. Ben Temime L, Gherib BS, Daldoul S, Bel Hadj Salah R, Abdesselem Mel M, Zaouche A: [Adenocarcinoma at the site of ileo-anal anastomosis in Crohn's disease: report of a case]. Tunis Med; 2005 Jan;83(1):55-8
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  • [Title] [Adenocarcinoma at the site of ileo-anal anastomosis in Crohn's disease: report of a case].
  • [Transliterated title] Adénocarcinome sur poche iléo-anale compli- quant une maladie de crohn. A propos d'un cas.
  • The pathological diagnosis carried of the specimen was Ulcerative colitis Then a proctectomy, followed by ileo-anal anastomosis, was performed in 1993.
  • After several episodes of pochitis and the appearance of intestinal lesions upstream the ileal pocket, the retained diagnosis was Crohn's colitis.
  • Eight years after the ileo-anal anastomosis, the patient developed an adenocarcinoma in the ileal pocket.
  • [MeSH-major] Adenocarcinoma / diagnosis. Anal Canal / surgery. Crohn Disease / surgery. Ileal Neoplasms / diagnosis. Ileum / surgery

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  • (PMID = 15881724.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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33. Halfdanarson TR, McWilliams RR, Donohue JH, Quevedo JF: A single-institution experience with 491 cases of small bowel adenocarcinoma. Am J Surg; 2010 Jun;199(6):797-803
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  • [Title] A single-institution experience with 491 cases of small bowel adenocarcinoma.
  • BACKGROUND: The optimal treatment of small bowel adenocarcinoma is unknown.
  • METHODS: The records of 491 patients with small bowel adenocarcinoma diagnosis between 1970 and 2005 were reviewed for patient and tumor characteristics, treatment effects, and survival.
  • RESULTS: The median age at diagnosis was 62 years.
  • The most common tumor locations were the duodenum (57%), jejunum (29%), and ileum (10%).
  • CONCLUSIONS: The prognosis of patients with small bowel adenocarcinoma is poor.
  • [MeSH-major] Adenocarcinoma / surgery. Intestinal Neoplasms / surgery. Intestine, Small
  • [MeSH-minor] Adult. Age Factors. Aged. Aged, 80 and over. Chi-Square Distribution. Female. Humans. Male. Middle Aged. Neoplasm Staging. Neoplasm, Residual. Prognosis. Proportional Hazards Models. Risk Factors. Sex Factors. Statistics, Nonparametric. Survival Rate. Treatment Outcome

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  • [Copyright] Published by Elsevier Inc.
  • (PMID = 20609724.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Chang HK, Yu E, Kim J, Bae YK, Jang KT, Jung ES, Yoon GS, Kim JM, Oh YH, Bae HI, Kim GI, Jung SJ, Gu MJ, Kim JY, Jang KY, Jun SY, Eom DW, Kwon KW, Kang GH, Park JB, Hong S, Lee JS, Park JY, Hong SM, Korean Small Intestinal Cancer Study Group: Adenocarcinoma of the small intestine: a multi-institutional study of 197 surgically resected cases. Hum Pathol; 2010 Aug;41(8):1087-96
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  • [Title] Adenocarcinoma of the small intestine: a multi-institutional study of 197 surgically resected cases.
  • Small intestinal adenocarcinoma is a rare malignant neoplasm, and its clinicopathologic characteristics have not been well elucidated.
  • A total of 197 small intestinal adenocarcinoma cases were collected from 22 institutions in South Korea and were evaluated for clinicopathologic factors that affect the prognosis of small intestinal adenocarcinoma patients using univariate and multivariate analyses.
  • Tumors were located in the duodenum of 108 cases (55%), the jejunum in 59 (30%), and the ileum in 30 (15%).
  • Synchronous or metachronous malignant tumors were identified in 31 cases (16%), including 13 colorectal and 10 stomach cancers.
  • The median survival time for all small intestinal adenocarcinoma patients was 39.7 months.
  • Compared with small intestinal adenocarcinomas without accompanying sporadic adenomas, small intestinal adenocarcinomas with accompanying adenomas were more well differentiated (P < .0001), with a more polypoid growth pattern (P < .0001), a lower pT classification (P < .0001), less perineural invasion (P = .01), and less lymphatic invasion (P = .03).
  • Small intestinal adenocarcinoma patients with associated sporadic adenomas (77%) had a significantly better 5-year survival rate than those without sporadic adenomas (38%, P = .02).
  • By univariate analysis, small intestinal adenocarcinoma patients had significantly different survival based on pT classification (P = .003), lymph node metastasis (P < .0001), distal location (jejunal and ileal carcinomas) (P = .003), retroperitoneal tumor seeding (P < .0001), vascular invasion (P = .007), lymphatic invasion (P = .001), peritumoral dysplasia (P = .004), and radiation therapy (P = .006).
  • In conclusion, (1) small intestinal adenocarcinomas are diagnosed at an advanced disease stage; therefore, the development of strategies for detection at an earlier stage is needed. (2) Small intestinal adenocarcinoma patients with an adenomatous component had a better survival than those without an adenomatous component. (3) Lymph node metastasis and distal location (jejunum and ileum) of tumor are the most important independent prognostic factors.
  • [MeSH-major] Adenocarcinoma / pathology. Duodenal Neoplasms / pathology. Ileal Neoplasms / pathology. Jejunal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Intestine, Small / pathology. Kaplan-Meier Estimate. Lymphatic Metastasis / pathology. Male. Middle Aged. Prognosis

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20334897.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Okubo K, Yoshioka S, Asukai K, Hata T, Nakanishi M, Maekawa T, Hama N, Kashiwazaki M, Taniguchi M, Tsujie M, Konishi M, Yano K, Fujimoto T: [A case report of primary adenocarcinoma of small intestine]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2792-4
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  • [Title] [A case report of primary adenocarcinoma of small intestine].
  • This is an account of a case of primary adenocarcinoma of the small intestine with peritoneal dissemination successfully treated with chemotherapy.
  • Abdominal computerized tomography revealed a bowel obstruction with tumor and the remarkable small bowel dilation of oral side of tumor.
  • The tumor was found at surgery to be at the ileum 15 cm proximal from the ileocecal region.
  • Peritoneal dissemination was recognized around the ileocecal region, so ileum partial resection was performed for the primary cancer lesion and dissemination region.
  • Pathological diagnosis of the resected specimen was adenocarcinoma with lymph nodes metastasis.
  • The peritoneal dissemination consisted of metastatic adenocarcinoma from small intestine.
  • Primary small intestinal adenocarcinoma is a rare disease, and it is often diagnosed as advanced cancer because of few characteristic symptoms.
  • So carcinoma of the small intestine usually has a poor prognosis.
  • [MeSH-major] Adenocarcinoma / therapy. Intestinal Neoplasms / therapy

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  • (PMID = 21224715.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 0 / Organoplatinum Compounds; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 2S9ZZM9Q9V / Bevacizumab; 5VT6420TIG / Oxonic Acid; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Folfox protocol
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36. Ruffolo C, Scarpa M, Polese L, D'Amico FE, Boetto R, Pozza A, D'Incà R, Checchin D, Sturniolo GC, Bassi N, Angriman I: Clinical presentation and diagnosis of intestinal adenocarcinoma in Crohn's disease: analysis of clinical predictors and of the life-time risk. J Gastrointest Surg; 2010 Nov;14(11):1746-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical presentation and diagnosis of intestinal adenocarcinoma in Crohn's disease: analysis of clinical predictors and of the life-time risk.
  • BACKGROUND: Late diagnosis of cancer in CD often occurs, and the prognosis is poor.
  • The primary aim of this study was to assess the relationship between clinical presentation and diagnosis of intestinal adenocarcinoma in CD; the secondary aim was to evaluate the timing of cancer occurrence in CD patients.
  • PATIENTS AND METHODS: Medical records of 12 consecutive patients with intestinal adenocarcinoma in CD and of 79 consecutive CD patients undergoing bowel surgery were reviewed.
  • Timing of intestinal adenocarcinoma occurrence in patients with CD was analyzed including all the 347 consecutive patients that had undergone surgery for CD in our institute from January 1984 to June 2008.
  • Carcinomas were localized in the terminal ileum in four cases, right colon in three, transverse colon in one, sigmoid colon in one, rectum in two, and an anorectal fistula in one.
  • At multivariate analysis only age (OR 1.057 (95% CI 0.999-1.107), p = 0.05) and obstruction (OR 6.530 (95% CI 1.533-27.806), p = 0.01) significantly predicted cancer diagnosis.
  • DISCUSSION: In CD, rectal bleeding, the most common alarm symptom for intestinal cancer, is not useful for an early diagnosis.
  • [MeSH-major] Adenocarcinoma / diagnosis. Crohn Disease / complications. Intestinal Neoplasms / diagnosis

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  • (PMID = 20628906.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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37. Bhanote M, Choksi M, Cassar P, Edelman M, DellaRatta R, Staszewski H: Metastatic adenocarcinoma of the colon and follicular lymphoma within the same lymph node: a case report and review of the literature. Int J Gastrointest Cancer; 2005;36(3):171-5
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  • [Title] Metastatic adenocarcinoma of the colon and follicular lymphoma within the same lymph node: a case report and review of the literature.
  • Concomitant adenocarcinoma and non-Hodgkin's lymphoma, both located in the intestinal tract, are unusual.
  • We report a unique case of moderately differentiated of the cecum and a simultaneous follicular lymphoma, Grade 1, of the terminal ileum and regional lymph nodes in a 55-yr-old man.
  • One lymph node was involved by both adenocarcinoma and follicular lymphoma.
  • To our knowledge, this is the fifteenth reported case of concurrent adenocarcinoma and non-Hodgkin's lymphoma of the intestine, but this is the first case with involvement of follicular lymphoma and adenocarcinoma within the same lymph node.
  • [MeSH-major] Adenocarcinoma / secondary. Colonic Neoplasms / pathology. Lymph Nodes / pathology. Lymphoma, Follicular / pathology. Neoplasms, Second Primary / pathology

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  • (PMID = 16720913.001).
  • [ISSN] 1537-3649
  • [Journal-full-title] International journal of gastrointestinal cancer
  • [ISO-abbreviation] Int J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Overman MJ, Kopetz S, Lin E, Abbruzzese JL, Wolff RA: Is there a role for adjuvant therapy in resected adenocarcinoma of the small intestine. Acta Oncol; 2010 May;49(4):474-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is there a role for adjuvant therapy in resected adenocarcinoma of the small intestine.
  • BACKGROUND: The benefit of adjuvant therapy for resected small bowel adenocarcinoma has not been proven.
  • We undertook a retrospective analysis to evaluate the benefit of adjuvant therapy in a clearly defined patient population with curatively resected small bowel adenocarcinoma.
  • MATERIAL AND METHODS: We identified 54 patients with small bowel adenocarcinoma who underwent margin-negative surgical resection and were evaluated after surgery at the University of Texas, M. D.
  • RESULTS: Median age was 55 years and primary tumor site was duodenum in 67%, jejunum in 20%, and ileum in 13%.
  • DISCUSSION: The use of adjuvant therapy for curatively resected small bowel adenocarcinoma was associated with an improvement in DFS.
  • [MeSH-major] Adenocarcinoma / therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Intestinal Neoplasms / therapy. Intestine, Small
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Chemotherapy, Adjuvant. Disease-Free Survival. Duodenal Neoplasms / therapy. Female. Follow-Up Studies. Humans. Ileal Neoplasms / therapy. Jejunal Neoplasms / therapy. Kaplan-Meier Estimate. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Proportional Hazards Models. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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  • (PMID = 20397775.001).
  • [ISSN] 1651-226X
  • [Journal-full-title] Acta oncologica (Stockholm, Sweden)
  • [ISO-abbreviation] Acta Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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39. McHugh SM, O'Donnell J, Gillen P: Synchronous association of rectal adenocarcinoma and three ileal carcinoids: a case report. World J Surg Oncol; 2009;7:21
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  • [Title] Synchronous association of rectal adenocarcinoma and three ileal carcinoids: a case report.
  • BACKGROUND: Synchronous midgut carcinoids with gastrointestinal adenocarcinoma are a rare but recognised association.
  • CASE PRESENTATION: The patient, a 74 year old woman, underwent anterior resection for a low rectal adenocarcinoma.
  • Intra-operatively 3 serosal deposits of tumour were noted in the distal ileum.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoid Tumor / pathology. Ileal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Rectal Neoplasms / pathology

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  • [Cites] Curr Opin Oncol. 2000 Jul;12(4):368-77 [10888424.001]
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  • (PMID = 19228386.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2649932
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40. Stratopoulos C, Papakonstantinou A, Anagnostopoulos G, Terzis I, Tzimas G, Gourgiotis S, Vamvouka C, Hadjiyannakis E: Intestinal neurofibromatosis and small-bowel adenocarcinoma: a single case study. Eur J Cancer Care (Engl); 2009 Sep;18(5):466-9
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  • [Title] Intestinal neurofibromatosis and small-bowel adenocarcinoma: a single case study.
  • However, the coexistence of neurofibromatosis with small-bowel adenocarcinoma is exceedingly rare.
  • We present an uncommon case of neurofibromatosis type 1, involving the small bowel in a 73-year-old man, who was admitted to our department with signs of acute abdomen.
  • At laparotomy, multiple mesenteric and intramural nodules were seen in the distal ileum.
  • These nodules obstructed ileal lumen, while the intestine wall was perforated in one point.
  • A wide resection of the affected ileum together with all visible nodules in the adjacent mesentery was performed.
  • Histology revealed neurofibromatosis type 1 with malignant transformation to small-bowel adenocarcinoma.
  • We suggest that adenocarcinoma of small bowel should be considered in the evaluation of acute abdominal pain in neurofibromatosis patients.
  • [MeSH-major] Adenocarcinoma / pathology. Ileal Neoplasms / pathology. Intestine, Small / pathology. Neoplasms, Multiple Primary / pathology. Neurofibromatosis 1 / pathology

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  • (PMID = 19473375.001).
  • [ISSN] 1365-2354
  • [Journal-full-title] European journal of cancer care
  • [ISO-abbreviation] Eur J Cancer Care (Engl)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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41. Lee SW, Sonoda T, Milsom JW: Three cases of adenocarcinoma following restorative proctocolectomy with hand-sewn anastomosis for ulcerative colitis: a review of reported cases in the literature. Colorectal Dis; 2005 Nov;7(6):591-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Three cases of adenocarcinoma following restorative proctocolectomy with hand-sewn anastomosis for ulcerative colitis: a review of reported cases in the literature.
  • The occurrence of adenocarcinoma adjacent to the ileoanal anastomotic site for ulcerative colitis is a serious but rare outcome.
  • [MeSH-major] Adenocarcinoma / etiology. Colitis, Ulcerative / surgery. Colonic Neoplasms / etiology. Proctocolectomy, Restorative / adverse effects
  • [MeSH-minor] Adult. Anal Canal / pathology. Anal Canal / surgery. Anastomosis, Surgical / methods. Cell Transformation, Neoplastic. Female. Humans. Ileum / pathology. Ileum / surgery. Male. Middle Aged. Surgical Stapling

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  • [CommentIn] Colorectal Dis. 2006 Jul;8(6):526-7 [16784478.001]
  • [CommentIn] Colorectal Dis. 2005 Nov;7(6):537 [16232231.001]
  • (PMID = 16232241.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 34
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42. Choi GY, Kim A, Kim CN, Yoon SJ, Jung SH, Ko BS, Yang HY, John BM, Kim SH, Nam HJ, Go H: [A case of subphrenic abscess with ileal fistula caused by metastatic adenocarcinoma of unknown origin]. Korean J Gastroenterol; 2005 Dec;46(6):471-4
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  • [Title] [A case of subphrenic abscess with ileal fistula caused by metastatic adenocarcinoma of unknown origin].
  • Reported cases of intestinal fistula caused by adenocarcinoma were complicated by direct invasion.
  • In this report, a 70-year-old male had a subphrenic abscess with intestinal fistula and the cause was a metastatic adenocarcinoma of unknown origin.
  • The fistulous tract between the abscess and ileum was demonstrated by tubogram via the drainage catheter in abscess.
  • Invasion of the ileum by metastatic adenocarcinoma was diagnosed by the histologic examination of surgical specimen.
  • [MeSH-major] Adenocarcinoma / secondary. Ileal Diseases / etiology. Ileal Neoplasms / secondary. Intestinal Fistula / etiology. Neoplasms, Unknown Primary. Subphrenic Abscess / etiology

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  • (PMID = 16371722.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
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43. Choudhry MN, Ali M, Hasan N: Small bowel obstruction secondary to gastric adenocarcinoma. BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Small bowel obstruction secondary to gastric adenocarcinoma.
  • A 77-year-old man presented with small bowel obstruction secondary to a solitary metastasis 7 years following resection of gastric carcinoma.
  • Further exploration revealed the presence of a small bowel tumour in the ileum causing obstruction.
  • A small bowel resection with side-to-side anastomosis was performed.
  • On microscopy, the appearance of the resected small bowel tumour was consistent with a metastasis from the previously resected gastric carcinoma.

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  • (PMID = 21785660.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3027531
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44. Erra S, Costamagna D, Botto G, Gemme C, Durando R: Sporadic flat ileal adenocarcinoma: an intriguing challenge in the comprehension of a rare neoplasia and its genesis. Case report and review of literature. G Chir; 2009 Mar;30(3):87-92
MedlinePlus Health Information. consumer health - Intestinal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sporadic flat ileal adenocarcinoma: an intriguing challenge in the comprehension of a rare neoplasia and its genesis. Case report and review of literature.
  • Small bowel adenocarcinoma is a rare tumor, with a still not well studied tumorigenesis process, usually presenting in an advanced stage.
  • The clinical diagnosis is often difficult; surgery is the treatment of choice when feasible, while the chemotherapeutic approach is still not well standardized.
  • At laparotomy the terminal ileum appeared chronically inflamed and thickened.
  • The gross appearance resembled an inflammatory bowel disease, but microscopic examination revealed the extensive presence of an infiltrating ileal adenocarcinoma.
  • Literature about small bowel adenocarcinoma has been reviewed for better understanding its pathogenesis.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Ileal Neoplasms / pathology. Ileal Neoplasms / surgery
  • [MeSH-minor] Aged. Anastomosis, Surgical. Diagnosis, Differential. Digestive System Surgical Procedures / methods. Humans. Male. Treatment Outcome

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  • (PMID = 19351457.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 44
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45. Overman MJ, Kopetz S, Wen S, Hoff PM, Fogelman D, Morris J, Abbruzzese JL, Ajani JA, Wolff RA: Chemotherapy with 5-fluorouracil and a platinum compound improves outcomes in metastatic small bowel adenocarcinoma. Cancer; 2008 Oct 15;113(8):2038-45
Hazardous Substances Data Bank. FLUOROURACIL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chemotherapy with 5-fluorouracil and a platinum compound improves outcomes in metastatic small bowel adenocarcinoma.
  • BACKGROUND: Metastatic small bowel adenocarcinoma (SBA) has a poor prognosis.
  • The primary tumor site was the jejunum in 35 patients (43%), duodenum in 30 patients (38%), ileum in 6 patients (8%), and nonspecified small bowel in 9 patients (11%).
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Intestinal Neoplasms / drug therapy. Intestine, Small / pathology
  • [MeSH-minor] Adult. Aged. Disease-Free Survival. Female. Fluorouracil / administration & dosage. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Recurrence, Local / drug therapy. Platinum Compounds / administration & dosage. Retrospective Studies

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  • [Copyright] (c) 2008 American Cancer Society.
  • (PMID = 18759326.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Platinum Compounds; U3P01618RT / Fluorouracil
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46. Thoree V, Skepper J, Deere H, Pele LC, Thompson RP, Powell JJ: Phenotype of exogenous microparticle-containing pigment cells of the human Peyer's patch in inflamed and normal ileum. Inflamm Res; 2008 Aug;57(8):374-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phenotype of exogenous microparticle-containing pigment cells of the human Peyer's patch in inflamed and normal ileum.
  • METHODS: PCs contained within PP were identified by routine haematoxylin and eosin (H&E) staining and dark field microscopy of archival ileal sections for: adenocarcinoma (n=16), colonic CD (n=23), non-CD colitis (n=10).
  • [MeSH-major] Ileum / pathology. Inclusion Bodies / metabolism. Inflammation / pathology. Peyer's Patches. Phenotype. Pigmentation

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  • (PMID = 18787776.001).
  • [ISSN] 1023-3830
  • [Journal-full-title] Inflammation research : official journal of the European Histamine Research Society ... [et al.]
  • [ISO-abbreviation] Inflamm. Res.
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / MC/ U105960399
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antigens, CD; EC 3.4.23.5 / Cathepsin D
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47. Lingohr P, Knoefel WT, Kleimann E, Rheinwalt KP: [Laparoscopic coincidental finding in a case of incomplete ileus: adenocarcinoma of the small intestine as first manifestation of Crohn's disease]. Zentralbl Chir; 2007 Dec;132(6):564-8
MedlinePlus Health Information. consumer health - Intestinal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Laparoscopic coincidental finding in a case of incomplete ileus: adenocarcinoma of the small intestine as first manifestation of Crohn's disease].
  • The case-study reminds of adenocarcinoma of the small intestine as a rare complication of Crohn's disease.
  • Epidemiological studies concerning small bowel carcinoma showed consumption of sugar and carbohydrates as pathogenetic factors, other conditions like ileostoma, ileumconduit, Crohn's disease and coeliac disease have been identified to some extent.
  • An adenoma-carcinoma sequence as in large intestine carcinoma has been discussed.
  • Diagnosis of early stages of adenocarcinoma of the small intestine is very difficult and thus might be impossible to differentiate from exacerbation or progressive stenosis of preexisting Crohn's disease.
  • If non-invasive diagnostic measures (ultrasound, small bowel enema, CT-scan, intestinoscopy, radiography, NMR-Sellink, capsule-endoscopy) fail to clear the situation a diagnostic laparoscopy or even laparotomy should not be delayed.
  • [MeSH-major] Adenocarcinoma / surgery. Crohn Disease / surgery. Ileal Neoplasms / surgery. Ileus / surgery. Incidental Findings. Laparoscopy
  • [MeSH-minor] Aged. Appendectomy. Cell Transformation, Neoplastic / pathology. Cholecystectomy, Laparoscopic. Cholelithiasis / diagnosis. Cholelithiasis / surgery. Diagnosis, Differential. Female. Humans. Ileum / pathology. Ileum / surgery. Intestinal Mucosa / pathology. Intestinal Mucosa / surgery. Neoplasm Invasiveness

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  • (PMID = 18098087.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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48. Kodaira C, Osawa S, Mochizuki C, Sato Y, Nishino M, Yamada T, Takayanagi Y, Takagaki K, Sugimoto K, Kanaoka S, Furuta T, Ikuma M: A case of small bowel adenocarcinoma in a patient with Crohn's disease detected by PET/CT and double-balloon enteroscopy. World J Gastroenterol; 2009 Apr 14;15(14):1774-8
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  • [Title] A case of small bowel adenocarcinoma in a patient with Crohn's disease detected by PET/CT and double-balloon enteroscopy.
  • Small bowel adenocarcinoma (SBA) in patients with Crohn's disease (CD) is quite rare, difficult to diagnose without surgery, and has a poor prognosis.
  • PET/CT detected an accumulation spot in the small bowel.
  • DBE revealed an ulcerative tumor in the ileum about 100 cm from the ileocecal valve.
  • An endoscopic forceps biopsy specimen showed poorly differentiated adenocarcinoma.
  • There were some longitudinal ulcer scars near the tumor, and the chronic inflammation in the small bowel appeared to be associated with the cancer development.
  • Since early diagnosis is extremely difficult in these cases, novel techniques, such as PET/CT and DBE, may be expected to help in making a preoperative diagnosis of the development of SBA in CD.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / etiology. Crohn Disease / complications. Endoscopy, Gastrointestinal / methods. Intestinal Neoplasms / diagnosis. Intestinal Neoplasms / etiology. Intestine, Small / pathology

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  • (PMID = 19360924.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2668786
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49. Gao C, Wang AY: Significance of increased apoptosis and Bax expression in human small intestinal adenocarcinoma. J Histochem Cytochem; 2009 Dec;57(12):1139-48

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Significance of increased apoptosis and Bax expression in human small intestinal adenocarcinoma.
  • Human small intestine accounts for 75% of the gastrointestinal (GI) length but for only 1-5% of GI tumors.
  • For this purpose, 77 samples from patients were examined by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling and immunohistochemistry, including 40 cases from normal small intestine (jejunum), 7 cases from jejunum and ileum adenocarcinomas, and 30 cases from normal colon.
  • The results showed that a significantly higher level of enterocyte apoptosis was observed in normal small intestine compared with small intestinal adenocarcinomas and normal colon (median of apoptotic index, 15.2% vs 0.1% and 1.6%, p<0.01).
  • In conclusion, increased apoptosis and expression of Bax, not Bcl-2 or the Bax/Bcl-2 ratio, may play some role in the relatively lower incidence of human small intestinal carcinomas.
  • [MeSH-major] Adenocarcinoma / pathology. Apoptosis. Gene Expression Regulation, Neoplastic. Intestinal Neoplasms / pathology. Intestine, Small / metabolism. Intestine, Small / pathology. bcl-2-Associated X Protein / metabolism

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  • (PMID = 19729672.001).
  • [ISSN] 1551-5044
  • [Journal-full-title] The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • [ISO-abbreviation] J. Histochem. Cytochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / bcl-2-Associated X Protein
  • [Other-IDs] NLM/ PMC2778087
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50. Fu XM, Dai X, Ding J, Zhu BT: Pancreas-specific protein disulfide isomerase has a cell type-specific expression in various mouse tissues and is absent in human pancreatic adenocarcinoma cells: implications for its functions. J Mol Histol; 2009 Jun;40(3):189-99
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pancreas-specific protein disulfide isomerase has a cell type-specific expression in various mouse tissues and is absent in human pancreatic adenocarcinoma cells: implications for its functions.
  • In the present study, we found that PDIp was also highly expressed in several other tissues in mice, including the stomach, cecum, ileum, adrenal glands, epididymis, and prostate.
  • In ileum, PDIp was exclusively expressed in Paneth cells.
  • In addition, high levels of PDIp expression were also detected in normal human pancreas, but its expression was mostly absent in human pancreatic duct adenocarcinoma and pancreatic cancer cell lines.
  • The absence of PDIp expression in pancreatic adenocarcinoma may serve as an additional biomarker for pancreatic cancer.

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  • (PMID = 19821078.001).
  • [ISSN] 1567-2387
  • [Journal-full-title] Journal of molecular histology
  • [ISO-abbreviation] J. Mol. Histol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA097109; United States / NCI NIH HHS / CA / CA97109; United States / NCRR NIH HHS / RR / P20RR021940
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Netherlands
  • [Chemical-registry-number] EC 5.3.4.1 / Protein Disulfide-Isomerases
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51. Ikeda J, Yamauchi A, Hoshida Y, Okamura S, Hashimoto K, Aozasa K, Morii E: Peripheral T-cell lymphoma developing at ileocolonic anastomosis site after colectomy for adenocarcinoma. Pathol Res Pract; 2010 Jun 15;206(6):376-8
MedlinePlus Health Information. consumer health - Colorectal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peripheral T-cell lymphoma developing at ileocolonic anastomosis site after colectomy for adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Colorectal Neoplasms / pathology. Colorectal Neoplasms / surgery. Lymphoma, T-Cell, Peripheral / pathology. Neoplasms, Second Primary / pathology
  • [MeSH-minor] Aged. Anastomosis, Surgical. Colectomy. Humans. Ileum / surgery. Intestine, Large / surgery. Male

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  • [Copyright] 2009 Elsevier GmbH. All rights reserved.
  • (PMID = 19836149.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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52. Knutsen A, Sielaff TD, Greeno E, Tuttle TM: Staged laparoscopic infusion of hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. J Gastrointest Surg; 2006 Jul-Aug;10(7):1038-43
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  • Primary malignancies included adenocarcinoma of the ileum (one patient), adenocarcinoma of the appendix (three patients), and adenocarcinoma of the gallbladder (one patient).
  • [MeSH-major] Adenocarcinoma / drug therapy. Antibiotics, Antineoplastic / administration & dosage. Hyperthermia, Induced / methods. Infusions, Parenteral / methods. Peritoneal Neoplasms / drug therapy

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  • (PMID = 16843875.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 50SG953SK6 / Mitomycin
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53. Yamamoto T, Fazio VW, Tekkis PP: Safety and efficacy of strictureplasty for Crohn's disease: a systematic review and meta-analysis. Dis Colon Rectum; 2007 Nov;50(11):1968-86
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  • The sites of strictureplasty were jejunum and/or ileum (94 percent), previous anastomosis (4 percent), duodenum (1 percent), and colon (1 percent).
  • Two patients developed adenocarcinoma at the site of previous jejunoileal strictureplasty.
  • CONCLUSIONS: Strictureplasty is a safe and effective procedure for jejunoileal Crohn's disease, including ileocolonic recurrence, and it has the advantage of protecting against further small bowel loss.
  • [MeSH-minor] Adenocarcinoma / etiology. Anastomosis, Surgical. Colonic Neoplasms / etiology. Humans. Ileum / surgery. Jejunum / surgery. Recurrence. Short Bowel Syndrome / etiology. Treatment Outcome

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  • (PMID = 17762967.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Review
  • [Publication-country] United States
  • [Number-of-references] 108
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54. Mijandrusić Sincić B, Kovac D, Jasić M, Grbas H, Uravić M, Depolo A: Crohn's disease and a gastrointestinal stromal tumor in an 81-year-old man--a rare coincidence. Zentralbl Chir; 2005 Dec;130(6):597-9
MedlinePlus Health Information. consumer health - Intestinal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the area of the terminal ileum, coecum and colon ascendens inflamed bowel loops were fixed together with fibrous adhesions.
  • Partial resection of the ileum with end-to-end anastomosis and right hemicolectomy with resection of the terminal ileum and end-to-end ileotransverse anastomosis were performed.
  • Changes in terminal ileum, coecum and colon ascendens were referred as Crohn's disease.
  • Although adenocarcinoma is well known in chronic, long-standing inflammatory bowel disease, other primary intestinal tumors are rare in those patients.
  • Furthermore, Crohn's disease can be a part of differential diagnosis of ileus, also in such an old man.
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Humans. Ileum / pathology. Ileum / surgery. Ileus / etiology. Ileus / pathology. Ileus / surgery. Male

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  • (PMID = 16382412.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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55. Yamaguchi N, Isomoto H, Shikuwa S, Ohnita K, Mizuta Y, Ito M, Kohno S, Nakao K: Proximal extension of backwash ileitis in ulcerative-colitis - associated colon cancer. Med Sci Monit; 2010 Jul;16(7):CS87-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Extension of the inflammatory process into the terminal ileum in ulcerative colitis is termed backwash ileitis.
  • Although initial endoscopic examination showed no abnormalities in the terminal ileum, a repeat colonoscopy 4 months later revealed erythema, absence of the vascular pattern, mucosal friability, and erosions within 30 cm of the terminal ileum in a continuous fashion from the cecum, and a flat, elevated lesion was found in the transverse colon.
  • On histopathologic examination, the patient had nonspecific, active, chronic inflammation of the ileal mucosa, consistent with backwash ileitis, and colonic adenocarcinoma.
  • Despite additional treatment with leukocytapheresis, the backwash ileitis progressed, with increased severity of mucosal inflammation and extensive erosions, 20 cm proximal to the primarily affected site of the ileum on repeat colonoscopy 2 months later.
  • The patient underwent a proctocolectomy and excision of the terminal ileum with an ileostomy.
  • CONCLUSIONS: Histopathology of the surgical specimen revealed marked backwash ileitis and submucosal, well-differentiated adenocarcinoma.
  • [MeSH-minor] Aged. Colonoscopy. Follow-Up Studies. Humans. Ileum / surgery. Male. Radiography, Abdominal

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  • (PMID = 20581781.001).
  • [ISSN] 1643-3750
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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56. Biancone L, Calabrese E, Palmieri G, Petruzziello C, Onali S, Sica GS, Cossignani M, Condino G, Das KM, Pallone F: Ileal lesions in patients with ulcerative colitis after ileo-rectal anastomosis: relationship with colonic metaplasia. World J Gastroenterol; 2008 Sep 14;14(34):5290-300
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIM: To assess whether in ulcerative colitis (UC) patients with ileo-rectal anastomosis (IRA), ileal lesions may develop in the neo-terminal-ileum and their possible relation with phenotypic changes towards colonic epithelium.
  • Ileal lesions were identified by ileoscopy with biopsies taken from the ileum (involved and uninvolved) and from the rectal stump.
  • RESULTS: Stenosing adenocarcinoma of the rectal stump was detected in 1 UC patient.
  • The neo-terminal ileum was therefore investigated in 10/11 UC patients.
  • Changes of the ileal content after colectomy may contribute to the development of colonic metaplasia, leading to ileal lesions both in the pouch and in the neo-terminal ileum after IRA.
  • [MeSH-major] Colitis, Ulcerative / pathology. Colitis, Ulcerative / surgery. Ileum / pathology. Ileum / surgery
  • [MeSH-minor] Adenocarcinoma / pathology. Adult. Aged. Aged, 80 and over. Anastomosis, Surgical / adverse effects. Capsule Endoscopy. Case-Control Studies. Colectomy / adverse effects. Colon / pathology. Colon / surgery. Female. Humans. Male. Metaplasia. Middle Aged. Rectal Neoplasms / pathology. Rectum / surgery. Young Adult

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  • (PMID = 18785281.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2744059
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57. Yokooji T, Murakami T, Yumoto R, Nagai J, Takano M: Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells. J Pharm Pharmacol; 2007 Apr;59(4):513-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells.
  • The site-specific function of multidrug-resistance-associated proteins (MRPs), especially MRP2 and MRP3, was examined in rat intestine and human colon adenocarcinoma (Caco-2) cells.
  • The rat jejunum exhibited a higher apical MRP2 and a lower basolateral MRP3 expression than ileum.
  • In accordance with the expression level, DNP-SG efflux to the mucosal surface was significantly greater in jejunum, while serosal efflux was greater in ileum.
  • Site-specific bidirectional efflux of DNP-SG was also observed in in-vivo studies, in which portal and femoral plasma levels and biliary excretion rate of DNP-SG were significantly higher when CDNB was administered to ileum.
  • Probenecid, an MRP inhibitor, significantly suppressed the mucosal efflux in jejunum and serosal efflux in ileum.
  • In contrast, probenecid significantly suppressed both apical and basolateral efflux of DNP-SG in Caco2 cells, though the inhibition was of small magnitude.
  • In conclusion, the efflux of DNP-SG from enterocytes mediated by MRPs exhibited a significant regional difference in rat intestine, indicating possible variability in intestinal bioavailabilities of MRP substrates, depending on their absorption sites along the intestine.
  • [MeSH-minor] Animals. Bile / metabolism. Biological Availability. Biological Transport. Blotting, Western. Caco-2 Cells. Dinitrochlorobenzene. Humans. Ileum / metabolism. Intestinal Mucosa / metabolism. Jejunum / metabolism. Male. Probenecid. Rats. Rats, Sprague-Dawley. Substrate Specificity

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  • (PMID = 17430634.001).
  • [ISSN] 0022-3573
  • [Journal-full-title] The Journal of pharmacy and pharmacology
  • [ISO-abbreviation] J. Pharm. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Membrane Transport Proteins; 0 / Multidrug Resistance-Associated Proteins; 0 / multidrug resistance-associated protein 2; 0 / multidrug resistance-associated protein 3; 26289-39-4 / S-(2,4-dinitrophenyl)glutathione; GAN16C9B8O / Glutathione; GE3IBT7BMN / Dinitrochlorobenzene; PO572Z7917 / Probenecid
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58. Shibahara K, Endo K, Ikeda T, Sakata H, Sadanaga N, Morita M, Kakeji Y, Maehara Y: Colon metastasis 20 years after the removal of ovarian cancer: Report of a case. Surg Today; 2009;39(2):153-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A biopsy of the lesion showed a group V, moderately differentiated adenocarcinoma.
  • A right hemicolectomy with a partial resection of the ileum and a lymphadenectomy was performed.
  • Immunohistochemical staining during the pathological diagnosis showed the lesion to be colon metastasis from a serous papillary adenocarcinoma of the ovary.
  • [MeSH-major] Adenocarcinoma / secondary. Colonic Neoplasms / secondary. Ovarian Neoplasms / pathology

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  • (PMID = 19198996.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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59. Ogata Y, Yamaguchi K, Sasatomi T, Uchida S, Akagi Y, Shirouzu K: [Treatment and outcome in small bowel cancer]. Gan To Kagaku Ryoho; 2010 Aug;37(8):1454-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment and outcome in small bowel cancer].
  • In adenocarcinoma of the small intestine, delays in diagnosis are frequent, and the majority of patients present with advanced- stage disease and either lymph node involvement or distant metastatic disease.
  • Recent retrospective and prospective studies have helped to clarify the optimal chemotherapy approach for advanced small bowel adenocarcinoma.
  • The 72nd Japanese Society for Cancer of the Colon and Rectum have conducted a retrospective review of Japanese patients with adenocarcinoma of the jejunum or ileum.
  • The data indicated that although not statistically significant, there was a trend in median overall survival favoring the chemotherapy for advanced jejunal or ileal adenocarcinoma (17 months vs. 8 months, p=0.114).
  • [MeSH-major] Adenocarcinoma / therapy. Intestinal Neoplasms / therapy. Intestine, Small

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  • (PMID = 20716869.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 13
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60. Egberts JH, Scharrer ML, Hinz S, Schafmayer C, Klomp HJ, Faendrich F, Tepel J: Small bowel cancer: single-centre results over a period of 12 years. Hepatogastroenterology; 2007 Jan-Feb;54(73):129-34

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Small bowel cancer: single-centre results over a period of 12 years.
  • BACKGROUND/AIMS: Tumors of the small bowel are rare, accounting for about 3-6% of all gastrointestinal neoplasms.
  • However, diagnosis and treatment are difficult and an ongoing challenge.
  • METHODOLOGY: Follow-up and clinical data of 43 patients with small bowel cancer who underwent surgery at our hospital.
  • RESULTS: Subgroups consisted of adenocarcinoma (n=16; 37.2%), neuroendocrine tumors (n=12; 27.9%), gastrointestinal stroma tumor (GIST) (n=10; 23.3%), lymphoma (n=3; 7%) and desmoid tumor (n=2; 4.6%).
  • Tumor localizations were within duodenum (46.5%), jejunum (16.3%) and ileum (37.2%).
  • Adenocarcinoma patients showed preponderance of advanced tumor stages: stage I/II in 5 pts, III/IV in 11 patients.
  • Localization was predominantly within the ileum (n=7).
  • Patients with neuroendocrine tumors showed best survival results (75/57%), GIST patients 60/35% and adenocarcinoma (27% each).
  • There was a strong trend towards better survival at early tumor stages in patients with adenocarcinoma and neuroendocrine tumors.
  • CONCLUSIONS: Early diagnosis is essential for prognosis of small bowel malignancies.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Adult. Aged. Aged, 80 and over. Carcinoid Tumor / mortality. Carcinoma, Neuroendocrine / diagnosis. Carcinoma, Neuroendocrine / epidemiology. Duodenal Neoplasms / diagnosis. Duodenal Neoplasms / epidemiology. Female. Gastrointestinal Stromal Tumors / epidemiology. Germany / epidemiology. Humans. Ileal Neoplasms / diagnosis. Ileal Neoplasms / epidemiology. Jejunal Neoplasms / epidemiology. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 17419246.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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61. O'Hara SP, Lin JJ: Accumulation of tropomyosin isoform 5 at the infection sites of host cells during Cryptosporidium invasion. Parasitol Res; 2006 Jun;99(1):45-54
eagle-i research resources. PMID 16479376 (Special Collections) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this study, we use in vitro cultured cell lines, human ileocecal adenocarcinoma HCT-8 and Chinese hamster ovary (CHO), and an in vivo mouse model to investigate the roles of tropomyosin isoforms in Cryptosporidium invasion.
  • In C. parvum-infected mice, accumulation and rearrangement of TM5 and TM4 were detected throughout the infected ileum.
  • [MeSH-minor] Animals. Blotting, Western. CHO Cells. Cell Line, Tumor. Cricetinae. Female. Fluorescent Antibody Technique. Gastric Mucosa / metabolism. Humans. Ileum / metabolism. Immunohistochemistry. Mice. Mice, Inbred C57BL. Protein Isoforms / metabolism

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  • (PMID = 16479376.001).
  • [ISSN] 0932-0113
  • [Journal-full-title] Parasitology research
  • [ISO-abbreviation] Parasitol. Res.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / HD18577
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Membrane Proteins; 0 / Protein Isoforms; 0 / Protozoan Proteins; 0 / TPM3 protein, human; 0 / Tropomyosin
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62. Eshra A, Al-Hendal A, Al Enezi M, Al-Mishaan M, Abo Dief W: One patient, two lymphomas, three primaries. Gulf J Oncolog; 2010 Jul;(8):39-43
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  • Concomitant adenocarcinoma and non-Hodgkin's lymphoma, both located in the intestinal tract, are unusual.
  • A case of true collision tumor of a marginal zone lymphoma and a moderately differentiated adenocarcinoma of the ascending colon (hepatic flexure) is reported.
  • Simultaneously, a third primary is identified as follicular lymphoma involving the terminal ileum.
  • Correlation with clinical history, radiology investigations, endoscopic findings and histological examination of the resected specimen as well as the use of ancillary techniques such as immunohistochemistry are the most useful in making the correct diagnosis of a synchronous three primaries involving the small bowel and colon.
  • [MeSH-major] Adenocarcinoma / pathology. Colonic Neoplasms / pathology. Ileal Neoplasms / pathology. Lymphoma, Non-Hodgkin / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 20601338.001).
  • [ISSN] 2078-2101
  • [Journal-full-title] The Gulf journal of oncology
  • [ISO-abbreviation] Gulf J Oncolog
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Kuwait
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63. Szanto I, Rubbia-Brandt L, Kiss P, Steger K, Banfi B, Kovari E, Herrmann F, Hadengue A, Krause KH: Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease. J Pathol; 2005 Oct;207(2):164-76
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It has been suggested to play a role in host defence, but also in cell growth and possibly malignant transformation.
  • In normal tissues, NOX1 expression was low in the ileum, intermediate in the right colon, and high in the left colon (p = 0.0056 right vs. left colon).
  • [MeSH-minor] Adenocarcinoma / metabolism. Adult. Aged. Aged, 80 and over. Animals. Colitis, Ulcerative / metabolism. Colon / metabolism. Crohn Disease / metabolism. Female. Humans. Ileum / metabolism. In Situ Hybridization / methods. Lymphocytes / metabolism. Male. Mice. Mice, Inbred BALB C. Middle Aged. Neoplasm Proteins / analysis. RNA, Messenger / analysis. RNA, Neoplasm / analysis. Rectal Neoplasms / metabolism. Rectum / metabolism

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  • [Copyright] Copyright (c) 2005 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
  • (PMID = 16086438.001).
  • [ISSN] 0022-3417
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Reactive Oxygen Species; EC 1.6.3.- / NOX1 protein, human; EC 1.6.3.1 / NADPH Oxidase
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64. Myśliwiec P, Gryko M, Kedra B, Zalewski B, Kowalska I, Myśliwiec J: [Neuroendocrine tumors of gastrointestinal tract in own material]. Endokrynol Pol; 2006 Mar-Apr;57(2):166-71
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  • Neuroendocrine tumors are rare gastrointestinal tract disorders, in which diagnosis and treatment are often difficult.
  • A 63-year-old female patient with primary diagnosis of neuroendicrine tumor metastases in liver was not successfully investigated for primary tumor in the preoperative period.
  • The laparotomy procedure indicated the malignant neuroendocrine tumor in the terminal ileum and metastases to the liver and to the greater omentum.
  • Pathologic examination of tissue sample revealed the diagnosis of carcinoid.
  • The patient underwent subtotal gastric resection for a pyloric ulcer, diagnosed as Adenocarcinoma G2 pT2N0M0 6 years before.
  • [MeSH-major] Adenocarcinoma / diagnosis. Carcinoid Tumor / diagnosis. Carcinoma, Neuroendocrine / secondary. Gastrointestinal Neoplasms / diagnosis. Liver Neoplasms / secondary. Neuroendocrine Tumors / diagnosis
  • [MeSH-minor] Antineoplastic Agents, Hormonal / therapeutic use. Combined Modality Therapy. Diagnosis, Differential. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Treatment Outcome

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  • (PMID = 16773593.001).
  • [ISSN] 0423-104X
  • [Journal-full-title] Endokrynologia Polska
  • [ISO-abbreviation] Endokrynol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal
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65. Garwood RA, Sawyer MD, Ledesma EJ, Foley E, Claridge JA: A case and review of bowel perforation secondary to metastatic lung cancer. Am Surg; 2005 Feb;71(2):110-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present a case of small bowel perforation secondary to metastatic lung cancer.
  • We identified 98 cases of perforated lung cancer metastasis to the small intestine.
  • Perforations occurred most often in the jejunum (53%) followed by ileum (28%).
  • Combined jejunum-ileum lesions accounted for 4 per cent of perforations.
  • Small bowel perforations were most often caused by adenocarcinoma (23.7%), squamous cell carcinoma (22.7%), large cell carcinoma (20.6%), and small cell carcinoma (19.6%).
  • The prevalence of small bowel perforation secondary to a given primary lung cancer histology varied by region.
  • Despite a high incidence of lung cancer, small bowel perforation secondary to lung cancer metastasis remains relatively rare.
  • Small bowel perforations are caused most often by adenocarcinoma; however, squamous cell and large cell carcinoma metastases are more likely to result in perforation.
  • Small bowel perforation in this setting has a significant impact on mortality, decreasing 1-year survival to less than 3 per cent.
  • [MeSH-major] Adenocarcinoma / secondary. Ileal Diseases / etiology. Ileal Neoplasms / secondary. Intestinal Perforation / etiology. Lung Neoplasms / pathology


66. Mineta S, Shimanuki K, Tsuchiya Y, Sugiura A, Kaneko M, Sugiyama Y, Akimaru K, Tajiri T: Resection of asynchronous quadruple advanced colonic carcinomas followed by reconstruction with ileal interposition between the transverse colon and rectum. J Nippon Med Sch; 2006 Jun;73(3):149-53

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / surgery. Colon, Transverse / surgery. Colonic Neoplasms / surgery. Ileum / surgery. Neoplasms, Multiple Primary / surgery. Rectum / surgery

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  • (PMID = 16790982.001).
  • [ISSN] 1345-4676
  • [Journal-full-title] Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
  • [ISO-abbreviation] J Nippon Med Sch
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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67. Culliford A, Daly J, Diamond B, Rubin M, Green PH: The value of wireless capsule endoscopy in patients with complicated celiac disease. Gastrointest Endosc; 2005 Jul;62(1):55-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Celiac disease may be complicated by symptoms that raise the suspicion of small-intestinal malignancy.
  • RESULTS: Findings were consistent with celiac disease in 87%: atrophy (68%), fissuring (62%), and mosaic pattern (19%), extending to the ileum in 34%.
  • CONCLUSIONS: WCE has a high yield in complicated celiac disease, by identifying mucosal abnormalities and by excluding adenocarcinoma.
  • [MeSH-minor] Abdominal Pain / complications. Adenocarcinoma / complications. Adult. Aged. Aged, 80 and over. Anemia, Iron-Deficiency / complications. Female. Follow-Up Studies. Humans. Jejunal Neoplasms / complications. Male. Middle Aged. Prospective Studies. Reproducibility of Results. Severity of Illness Index

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  • (PMID = 15990820.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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68. Bardakcioglu O, Ahmed S: Single incision laparoscopic total abdominal colectomy with ileorectal anastomosis for synchronous colon cancer. Tech Coloproctol; 2010 Sep;14(3):257-61

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  • A single incision laparoscopic total abdominal colectomy with an ileorectal anastomosis and intraoperative CO(2) colonoscopy was performed for a patient with synchronous adenocarcinoma of the cecum and the sigmoid colon.
  • [MeSH-major] Adenocarcinoma / surgery. Cecal Neoplasms / surgery. Colectomy / methods. Laparoscopy / methods. Neoplasms, Multiple Primary / surgery. Sigmoid Neoplasms / surgery
  • [MeSH-minor] Anastomosis, Surgical / methods. Colonoscopy. Follow-Up Studies. Humans. Ileum / surgery. Male. Middle Aged. Neoplasm Staging. Rectum / surgery. Risk Assessment. Treatment Outcome

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  • (PMID = 20502930.001).
  • [ISSN] 1128-045X
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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69. West NP, Hohenberger W, Weber K, Perrakis A, Finan PJ, Quirke P: Complete mesocolic excision with central vascular ligation produces an oncologically superior specimen compared with standard surgery for carcinoma of the colon. J Clin Oncol; 2010 Jan 10;28(2):272-8
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  • METHODS: The fresh photographs of 49 CME and CVL specimens from Erlangen and 40 standard specimens from Leeds, United Kingdom, for primary colonic adenocarcinoma were collected.
  • RESULTS: CME and CVL surgery removed more tissue compared with standard surgery in terms of the distance between the tumor and the high vascular tie (median, 131 v 90 mm; P < .0001), the length of large bowel (median, 314 v 206 mm; P < .0001), and ileum removed (median, 83 v 63 mm; P = .003), and the area of mesentery (19,657 v 11,829 mm(2); P < .0001).
  • [MeSH-major] Adenocarcinoma / surgery. Colectomy / methods. Colonic Neoplasms / surgery

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  • (PMID = 19949013.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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70. Constantin V, Socea B, Moculescu C, Sireţeanu G, Popa F: [Enteral non-Hodgkin lymphoma in young age--difficult diagnosis]. Chirurgia (Bucur); 2009 Sep-Oct;104(5):607-10
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  • [Title] [Enteral non-Hodgkin lymphoma in young age--difficult diagnosis].
  • Lately, we have been confronted with an increased number of malignant tumors of the large bowel, appearing at younger patients.
  • Among all histopathologic forms of malignant colonic tumors treated in our Clinic, lymphoma is the fifth as frequency of apparition, respectively the fourth at patients less than 40 years old.
  • We present the case of a 22-years-old patient, having colonic polyposis and multicentric non-Hodgkin lymphoma of the terminal ileum and ascending colon.
  • The rest of malignant colonic tumors developed on patients with rectocolonic polyposis were adenocarcinoma.
  • [MeSH-major] Colonic Neoplasms / diagnosis. Ileal Neoplasms / diagnosis. Lymphoma, Non-Hodgkin / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenomatous Polyposis Coli / diagnosis. Adult. Colectomy / methods. Colon, Ascending / pathology. Diagnosis, Differential. Humans. Male. Prognosis. Treatment Outcome

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  • (PMID = 19943562.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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71. Machimoto T, Doi R, Ogawa K, Masui T, Seo S, Uemoto S: Abdominal wall recurrence of Hilar bile duct cancer 12 years after a curative resection: report of a case. Surg Today; 2009;39(1):72-6
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  • Ten years later (April 2005), she noted a small mass in the abdominal wall.
  • With a diagnosis of a possible recurrence of bile duct cancer, a laparotomy was thus performed.
  • The abdominal wall tumor was buried in the rectus abdominis muscle and was tightly attached to the ileum.
  • A histopathological examination of the resected specimen revealed tubular adenocarcinoma that closely resembled the original primary bile duct cancer.
  • [MeSH-major] Abdominal Neoplasms / pathology. Adenocarcinoma / pathology. Bile Duct Neoplasms / pathology. Bile Ducts / pathology. Neoplasms, Second Primary / pathology

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  • (PMID = 19132474.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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72. Abbrederis K, Kremer M, Schuhmacher C: [Ischemic anastomotic bowel perforation during treatment with bevacizumab 10 months after surgery]. Chirurg; 2008 Apr;79(4):351-5
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  • OBJECTIVE: We report a 61-year-old woman with adenocarcinoma of the colon ascendens who underwent hemicolectomy and adjuvant chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin.
  • Because of anastomotic insufficiency 8 days later, a further revision had to be done and the terminal ileum and the colon were brought out through a stoma.
  • [MeSH-major] Anastomosis, Surgical. Angiogenesis Inhibitors / adverse effects. Antibodies, Monoclonal / adverse effects. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Colectomy. Colonic Neoplasms / surgery. Ileum / blood supply. Ileum / surgery. Intestinal Perforation / chemically induced. Ischemia / chemically induced. Surgical Wound Dehiscence / chemically induced
  • [MeSH-minor] Antibodies, Monoclonal, Humanized. Bevacizumab. Camptothecin / adverse effects. Camptothecin / analogs & derivatives. Camptothecin / therapeutic use. Colitis, Ischemic / chemically induced. Colitis, Ischemic / diagnosis. Colitis, Ischemic / pathology. Colitis, Ischemic / surgery. Female. Fluorouracil / adverse effects. Fluorouracil / therapeutic use. Humans. Ileostomy. Leucovorin / adverse effects. Leucovorin / therapeutic use. Lymphatic Metastasis / pathology. Middle Aged. Neoplasm Staging. Reoperation. Tomography, X-Ray Computed

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  • [CommentIn] Chirurg. 2008 Apr;79(4):356-60 [17453166.001]
  • (PMID = 17453167.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 2S9ZZM9Q9V / Bevacizumab; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; XT3Z54Z28A / Camptothecin; IFL protocol
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73. Trabelsi A, Ali AB, Yacoub-Abid LB, Stita W, Mokni M, Korbi S: Primary invasive micropapillary carcinoma of the colon: case report and review of the literature. Pathologica; 2008 Oct;100(5):428-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Papillary / pathology. Liver Neoplasms / secondary. Neoplasms, Multiple Primary / pathology. Sigmoid Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Colectomy. Colonoscopy. Humans. Ileum / pathology. Keratin-20 / analysis. Lymph Node Excision. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Proteins / analysis

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  • (PMID = 19253607.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-20; 0 / Neoplasm Proteins
  • [Number-of-references] 7
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74. Roos D, Busch OR, van Lanschot JJ: [Primary colon carcinoma in a colon interposition graft after oesophageal resection]. Ned Tijdschr Geneeskd; 2007 Sep 22;151(38):2111-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 79-year-old man presented with a massive subcutaneous swelling due to extreme dilatation ofa subcutaneously interposed right-sided hemicolon; 7 years earlier he had undergone oesophageal resection and gastric tube reconstruction for a poorly differentiated adenocarcinoma of the distal oesophagus.
  • One year later the continuity of the gastrointestinal tract was restored by a right-sided isoperistaltic colon graft: the terminal ileum, including the ileocecal valve, was anastomosed to the pre-existing cervical portion of the oesophagus.
  • The dilatation was caused by an obstructive adenocarcinoma located in the distal part of the interposed colon in combination with an intact ileocecal valve in the neck.
  • [MeSH-minor] Adenocarcinoma / complications. Adenocarcinoma / surgery. Aged. Anastomosis, Surgical. Esophageal Fistula / complications. Esophageal Fistula / surgery. Esophageal Neoplasms / complications. Esophageal Neoplasms / surgery. Esophagectomy. Humans. Intestinal Obstruction / etiology. Intestinal Obstruction / surgery. Male. Reoperation. Treatment Outcome

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  • (PMID = 17948828.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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75. Pagano S, Ruggeri P, Rovellini P, Bottanelli A: The anterior ileal conduit: results of 100 consecutive cases. J Urol; 2005 Sep;174(3):959-62; discussion 962
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  • MATERIALS AND METHODS: We leave the conduit in its natural isoperistaltic anterior position, the ureters are anastomosed in an anterior position on their own side, using a short ileum segment.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma, Squamous Cell / surgery. Carcinoma, Transitional Cell / surgery. Cystectomy. Postoperative Complications / etiology. Urinary Bladder Neoplasms / surgery. Urinary Diversion / methods
  • [MeSH-minor] Adult. Aged. Anastomosis, Surgical / methods. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Outcome and Process Assessment (Health Care). Ureter / surgery

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  • (PMID = 16094008.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Han SL, Cheng J, Zhou HZ, Guo SC, Jia ZR, Wang PF: Surgically treated primary malignant tumor of small bowel: a clinical analysis. World J Gastroenterol; 2010 Mar 28;16(12):1527-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgically treated primary malignant tumor of small bowel: a clinical analysis.
  • AIM: To evaluate the clinical presentation, treatment and survival of patients with primary malignant tumor of small bowel (PMTSB).
  • Ileum was the most common site of tumor (44.7%), followed by jejunum (30.5%) and duodenum (24.8%).
  • Twenty-seven adenocarcinoma patients and 13 malignant lymphoma patients received adjuvant chemotherapy with 5-fluorouracil and cyclophosphamide, adriamycin, vincristine and prednisone, respectively.
  • Adenocarcinoma was found in 73.7% (42/57), 21.1% (12/57) and 15.8% (9/57) of the patients, respectively.
  • Malignant lymphoma was demonstrated in 69.2% (9/13), 30.8% (4/13) and 0% (0/13) of the patients, respectively.
  • CONCLUSION: En bloc resection is the principal therapy for most PMTSB and chemotherapy is the important treatment modality for malignant lymphoma and other malignant tumors of small bowel which cannot be radically removed.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoid Tumor / surgery. Digestive System Surgical Procedures. Gastrointestinal Stromal Tumors / surgery. Intestinal Neoplasms / surgery. Intestine, Small / surgery. Lymphoma / surgery
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Proportional Hazards Models. Retrospective Studies. Risk Assessment. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 20333796.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2846261
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77. Kudo K, Funayama Y, Fukushima K, Shibata C, Takahashi K, Ogawa H, Ueno T, Haneda S, Watanabe K, Koyama A, Hayashi K, Hiwatashi N, Kinouchi Y, Shimosegawa T, Sasaki I: [Carcinoma arising from ileorectal fistula in a patient with Crohn's disease]. Nihon Shokakibyo Gakkai Zasshi; 2007 Oct;104(10):1492-7
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  • A 72-year-old man was given a diagnosis of Crohn's disease in 1976 at age 44, and partial resection of is ileum was performed.
  • Ileocecal resection, partial resection of is small intestine and loop sigmoid colostomy were performed.
  • Endoscopic examination showed a fistula orifice in the rectum and biopsy of the fistula revealed mucinous adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / etiology. Crohn Disease / complications. Ileal Diseases / complications. Intestinal Fistula / complications. Rectal Fistula / complications. Rectal Neoplasms / etiology

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  • (PMID = 17917397.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 12
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78. Romero Vázquez J, Caunedo Alvarez A, Rodríguez-Téllez M, Sánchez Yagüe A, Pellicer Bautista F, Herrerías Gutiérrez JM: Previously unknown stricture due to radiation therapy diagnosed by capsule endoscopy. Rev Esp Enferm Dig; 2005 Jun;97(6):449-54
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  • We present the case of a 60 year-old woman who had been diagnosed ten years before with endometrial adenocarcinoma, and who underwent hysterectomy with double adnexectomy and subsequent radiation therapy.
  • The patient consulted for abdominal pain and ferropenic anemia of several years standing, and had negative results following radiographic and endoscopic conventional techniques, reason why she was subjected to a capsule endoscopy study that revealed the presence of an ulcerated ileal stricture, which caused the asymptomatic retention of the capsule within the ileum.
  • This case shows the role capsule endoscopy may play in the diagnosis of this condition.
  • [MeSH-major] Endoscopy, Gastrointestinal / methods. Ileal Diseases / diagnosis. Ileal Diseases / etiology. Intestinal Obstruction / diagnosis. Intestinal Obstruction / etiology. Radiation Injuries / diagnosis. Radiotherapy / adverse effects
  • [MeSH-minor] Abdominal Pain / etiology. Adenocarcinoma / radiotherapy. Adenocarcinoma / surgery. Capsules. Endometrial Neoplasms / radiotherapy. Endometrial Neoplasms / surgery. Female. Follow-Up Studies. Humans. Hysterectomy. Laparotomy. Middle Aged. Time Factors. Treatment Outcome

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  • (PMID = 16011419.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Capsules
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79. Rink AD, Vestweber B, Vestweber KH: Modified ileocecal interposition. The final sphincter-saving solution after failed salvage surgery for anastomotic complications of low anterior resection. Dig Surg; 2008;25(5):359-63

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / surgery. Anal Canal. Cecum / transplantation. Ileum / transplantation. Proctocolectomy, Restorative / methods. Rectal Fistula / surgery. Rectal Neoplasms / surgery

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  • (PMID = 18957851.001).
  • [ISSN] 1421-9883
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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80. Wilhelm TJ, Knoll T, Weisser G, Grobholz R, Köhrmann KU, Post S: Urothelial carcinoma of the ureter, giant rectal stone and sigmoid carcinoma 55 years after ureterosigmoidostomy. Scand J Urol Nephrol; 2006;40(2):172-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenocarcinoma / pathology. Humans. Ileum / surgery. Male. Middle Aged. Reconstructive Surgical Procedures. Sigmoidoscopy. Tomography, X-Ray Computed. Ureterostomy

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  • (PMID = 16608820.001).
  • [ISSN] 0036-5599
  • [Journal-full-title] Scandinavian journal of urology and nephrology
  • [ISO-abbreviation] Scand. J. Urol. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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81. Hwangbo S, Kim J, Kim H, Kim J, Kang C, Lee H: Two separated ileal adenocarcinomas in neurofibromatosis type 1. Yonsei Med J; 2007 Dec 31;48(6):1039-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / pathology. Ileal Neoplasms / pathology. Neurofibromatosis 1 / pathology
  • [MeSH-minor] Adult. Humans. Ileum / pathology. Intestinal Mucosa / pathology. Male

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  • (PMID = 18159599.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2628198
  • [Keywords] NOTNLM ; Neurofibromatosis / adenocarcinoma / ileum
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82. Minordi LM, Vecchioli A, Mirk P, Filigrana E, Poloni G, Bonomo L: Multidetector CT in small-bowel neoplasms. Radiol Med; 2007 Oct;112(7):1013-25
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  • [Title] Multidetector CT in small-bowel neoplasms.
  • PURPOSE: The aim of this study was to assess the diagnostic potential of multidetector computed tomography (MDCT) in the evaluation of small-bowel neoplasms.
  • MATERIALS AND METHODS: We studied 120 patients with suspected small-bowel disease by 16-slice MDCT after oral administration of a polyethylene glycol solution (n=56) or methylcellulose via a nasojejunal tube (n=64).
  • RESULTS: Fifteen patients were found to be affected by small-bowel neoplasm (six had non-Hodgkin's lymphoma, three had carcinoid tumour, two had Peutz-Jeghers syndrome, two had adenocarcinoma, two had melanoma metastases, one had lipoma).
  • CONCLUSIONS: MDCT performed after bowel-loop distension with low-density contrast material and IV administration of iodinated contrast agent is a reliable method for diagnosing and staging small-bowel neoplasms.
  • [MeSH-major] Adenocarcinoma / radiography. Carcinoid Tumor / radiography. Ileal Neoplasms / radiography. Jejunal Neoplasms / radiography. Lipoma / radiography. Lymphoma, Non-Hodgkin / radiography. Peutz-Jeghers Syndrome / radiography. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Administration, Oral. Barium Sulfate / administration & dosage. Biopsy. Chi-Square Distribution. Contrast Media / administration & dosage. Enema. Female. Humans. Ileum / pathology. Image Processing, Computer-Assisted. Injections, Intravenous. Jejunum / pathology. Male. Methylcellulose / administration & dosage. Polyethylene Glycols / administration & dosage. Radiographic Image Enhancement. Sensitivity and Specificity

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  • (PMID = 17952678.001).
  • [ISSN] 0033-8362
  • [Journal-full-title] La Radiologia medica
  • [ISO-abbreviation] Radiol Med
  • [Language] eng; ita
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Contrast Media; 25BB7EKE2E / Barium Sulfate; 30IQX730WE / Polyethylene Glycols; 9004-67-5 / Methylcellulose
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83. Rink AD, Haaf F, Knupper N, Vestweber KH: Prospective randomised trial comparing ileocaecal interposition and colon-J-pouch as rectal replacement after total mesorectal excision. Int J Colorectal Dis; 2007 Feb;22(2):153-60

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  • [MeSH-major] Adenocarcinoma / surgery. Cecum / surgery. Ileum / surgery. Proctocolectomy, Restorative. Rectal Neoplasms / surgery

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  • (PMID = 16625377.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] Germany
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84. Hatzaras I, Palesty JA, Abir F, Sullivan P, Kozol RA, Dudrick SJ, Longo WE: Small-bowel tumors: epidemiologic and clinical characteristics of 1260 cases from the connecticut tumor registry. Arch Surg; 2007 Mar;142(3):229-35
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  • [Title] Small-bowel tumors: epidemiologic and clinical characteristics of 1260 cases from the connecticut tumor registry.
  • OBJECTIVE: To examine the epidemiology and clinical characteristics of small-bowel cancer.
  • DESIGN: Patients with small-bowel tumors reported between 1980 and 2000, studied retrospectively.
  • PATIENTS: One thousand sixty small-bowel cancer cases: 628 men (49.84%) and 632 women (50.16%).
  • RESULTS: The most common location of small-bowel tumors was the ileum (374 cases; 29.7%), followed by the duodenum (320 cases; 25.4%) and the jejunum (193 cases; 15.3%).
  • The most prevalent histologic type was carcinoid (417 cases; 33%), followed by adenocarcinoma (341 cases; 27%) and lymphoma (205 cases; 16.3%).
  • CONCLUSIONS: The incidence of small-bowel tumors in Connecticut has increased during the past 2 decades, with the highest rate of increase in men.
  • Carcinoid tumors are the most common small intestinal cancers identified histologically, followed by adenocarcinomas.
  • The former seems to be more frequently seen in the ileum, the latter in the duodenum.
  • Surgery is the treatment of choice for the cure or palliation of small-bowel cancers.

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  • (PMID = 17372046.001).
  • [ISSN] 0004-0010
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Quah HM, Samad A, Maw A: Ileostomy carcinomas a review: the latent risk after colectomy for ulcerative colitis and familial adenomatous polyposis. Colorectal Dis; 2005 Nov;7(6):538-44
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  • RESULTS: The risk of malignancy following ileostomy formation appears to be increased compared to the very low incidence of primary small bowel carcinoma.
  • Chronic physical or chemical irritation of the stoma may predispose the ileal mucosa to colonic metaplasia with subsequent adenoma formation, dysplasia and invasive malignant change.
  • [MeSH-major] Adenocarcinoma / etiology. Adenomatous Polyposis Coli / surgery. Colitis, Ulcerative / surgery. Ileal Neoplasms / etiology. Ileostomy / adverse effects
  • [MeSH-minor] Colonic Pouches. Humans. Ileum / pathology. Intestinal Mucosa / pathology. Prognosis


86. Monte MJ, Ballestero MR, Briz O, Perez MJ, Marin JJ: Proapoptotic effect on normal and tumor intestinal cells of cytostatic drugs with enterohepatic organotropism. J Pharmacol Exp Ther; 2005 Oct;315(1):24-35
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  • The proapoptotic effect of cisplatin bile acid derivatives Bamet-R2 [cis-diamminechloro-cholylglycinate-platinum(II)] and Bamet-UD2 [cis-diammine-bisursodeoxycholate-platinum(II)], developed to treat liver and intestinal tumors, was investigated in vitro using human enterohepatic cells HepG2 (hepatoblastoma), LS 174T (colon adenocarcinoma), and its cisplatin-resistant subline LS 174T/R.
  • The degree of necrosis (lactate dehydrogenase release) induced by these three drugs was small and similar in all cell types.
  • Oral administration of Bamet-UD2 to mice induced mild apoptosis in the small intestine (ileum > duodenum), which was not severe enough to modify its structure or function as determined by water absorption and glycocholic acid uptake by in situ perfused ileum.
  • [MeSH-major] Antineoplastic Agents / pharmacology. Apoptosis / drug effects. Intestinal Neoplasms / drug therapy. Intestine, Small / drug effects. Organoplatinum Compounds / pharmacology. Ursodeoxycholic Acid / analogs & derivatives

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  • (PMID = 15985617.001).
  • [ISSN] 0022-3565
  • [Journal-full-title] The Journal of pharmacology and experimental therapeutics
  • [ISO-abbreviation] J. Pharmacol. Exp. Ther.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Bamet-UD2; 0 / DNA Adducts; 0 / Organoplatinum Compounds; 0 / diamminebis(ursodeoxycholate(O,O'))platinum(II); 724L30Y2QR / Ursodeoxycholic Acid
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87. Oble DA, Mino-Kenudson M, Goldsmith J, Hodi FS, Seliem RM, Dranoff G, Mihm M, Hasserjian R, Lauwers GY: Alpha-CTLA-4 mAb-associated panenteritis: a histologic and immunohistochemical analysis. Am J Surg Pathol; 2008 Aug;32(8):1130-7
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  • Monoclonal antibodies (mAbs) against the cytotoxic T lymphocyte antigen-4 (CTLA-4) molecule are used as an adjuvant to experimental tumor immunization protocols in the treatment of malignant melanomas and ovarian cancers.
  • We report herein our observations of 5 patients who developed severe gastrointestinal toxicity affecting the gastric, small intestinal, and colonic mucosa.
  • Cryptitis and glandular inflammation were observed in the colon, ileum, and stomach, whereas villous blunting was present in the ileal and duodenal mucosa.
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / immunology. Adenocarcinoma / pathology. Aged. CTLA-4 Antigen. Diarrhea / chemically induced. Diarrhea / immunology. Female. Humans. Male. Melanoma / drug therapy. Melanoma / immunology. Melanoma / pathology. Middle Aged. Ovarian Neoplasms / drug therapy. Ovarian Neoplasms / immunology. Ovarian Neoplasms / pathology. Treatment Outcome

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  • (PMID = 18545145.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, CD; 0 / CTLA-4 Antigen; 0 / CTLA4 protein, human; 0 / ipilimumab
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88. Nagi B, Rana SS, Kochhar R, Bhasin DK: Sonoenteroclysis: a new technique for the diagnosis of small bowel diseases. Abdom Imaging; 2006 Jul-Aug;31(4):417-24
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  • [Title] Sonoenteroclysis: a new technique for the diagnosis of small bowel diseases.
  • BACKGROUND: Radiologic evaluation of small bowel is usually done by barium examination, which involves considerable radiation exposure.
  • A new sonographic method, sonoenteroclysis, is a promising technique for diagnosing small intestinal disorders.
  • METHODS: Forty-five consecutive patients with suspected small bowel disorder were studied.
  • Small bowel wall thickness, luminal narrowing, intestinal dilatation, peristalsis, and extraintestinal complications were noted.
  • Of 45 patients, 10 showed normal small bowel on sonoenteroclysis and barium enteroclysis.
  • Sonoenteroclysis displayed normal diameters smaller than 3.0 and 2.0 cm for the jejunum and ileum, respectively.
  • These were diagnosed subsequently as cases of tuberculosis (n = 23), celiac disease (n = 6), adenocarcinoma (n = 2), leiomyoma (n = 2), Immunoproliferative small intestinal disease (n = 1), and segmental enteritis (n = 1).
  • CONCLUSIONS: The diagnostic accuracy of sonoenteroclysis for detecting small bowel lesions is comparable to that of barium enteroclysis.
  • This new, widely available, inexpensive, and undemanding technique can be used as an initial investigation in the evaluation of patients with small bowel disorders.
  • [MeSH-major] Intestinal Diseases / ultrasonography. Intestine, Small / ultrasonography

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  • (PMID = 16447095.001).
  • [ISSN] 0942-8925
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 25BB7EKE2E / Barium Sulfate; 30IQX730WE / Polyethylene Glycols
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89. Uchiyama K, Nakamura M, Tsukinaga S, Koido S, Yamane T, Fujise K, Yoshimoto K, Ishii T, Ohmura M, Yamaguchi Y, Tajiri H: [A case of widespread ileal stenosis caused by metastatic disseminated peritoneal carcinomatosis from lung cancer resected 8 years previously]. Nihon Shokakibyo Gakkai Zasshi; 2007 Mar;104(3):381-7
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  • Because small bowel enema study showed widespread stricture of the ileum, we performed an operation.
  • During the operation we diagnosed metastatic small bowel carcinoma.
  • Because the resected sample of the small bowel carcinoma was similar to the lung carcinoma pathologically and detailed examination after the operation showed no other neoplasm, we considered this case to be small bowel metastasis of the lung carcinoma resected 8 years previously.
  • [MeSH-major] Adenocarcinoma / secondary. Ileal Diseases / etiology. Ileal Neoplasms / secondary. Lung Neoplasms / pathology. Peritoneal Neoplasms / secondary. Pneumonectomy


90. Aalbers AG, ten Kate M, van Grevenstein WM, Hofland LJ, Wiemer EA, Jeekel J, van Eijck CH: A small mammal model of tumour implantation, dissemination and growth factor expression after partial hepatectomy. Eur J Surg Oncol; 2008 Apr;34(4):469-75
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  • [Title] A small mammal model of tumour implantation, dissemination and growth factor expression after partial hepatectomy.
  • Finally, phX was compared with an ileum resection (ilX).
  • [MeSH-major] Adenocarcinoma / immunology. Colorectal Neoplasms / surgery. Liver Neoplasms / surgery. Lung Neoplasms / immunology
  • [MeSH-minor] Animals. Cell Adhesion. Cell Line, Tumor. Disease Models, Animal. Hepatectomy. Intercellular Signaling Peptides and Proteins / biosynthesis. Liver Regeneration / immunology. Male. Neoplasm Metastasis. Neoplasm Transplantation. Rats. Rats, Wistar. Receptors, Growth Factor / biosynthesis

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  • (PMID = 17442529.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Intercellular Signaling Peptides and Proteins; 0 / Receptors, Growth Factor
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91. Takahashi S, Iiai T, Shimada Y, Kobayashi Y, Suda K, Iwaya A, Maruyama S, Tani T, Hatakeyama K: [A long-term survival case of far-advanced colon cancer with Virchow's lymph node and lung metastasis that responded to multidisciplinary therapy]. Gan To Kagaku Ryoho; 2009 Jan;36(1):127-9
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  • Under a diagnosis of advanced cecal colon cancer with metastasis to Virchow's and paraaortic lymph nodes and lungs, a laparoscopic-assisted ileocecal resection with D2 lymph node dissection was performed.
  • Histological examination of the resected specimens revealed moderately-differentiated adenocarcinoma which had invaded the terminal ileum.
  • The lesion was judged to be SI(ileum), N2, H0, P0, M1(Virchow's lymph node, No. 216, lungs), Stage IV.
  • [MeSH-minor] Aged. Biopsy. Carcinoembryonic Antigen / blood. Combined Modality Therapy. Humans. Lymphatic Metastasis / pathology. Male. Neoplasm Staging. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19151578.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Carcinoembryonic Antigen
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92. Nagano Y, Sekido H, Matsuoi K, Ohtsuki K, Gorai K, Kunisaki C, Ike H, Imada T, Shimada H: Successful pancreatoduodenectomy for carcinoma of the ampulla of vater after esophagectomy with remnant gastrectomy. Hepatogastroenterology; 2005 May-Jun;52(63):933-5
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  • Furthermore, he had undergone subtotal esophagectomy with remnant gastrectomy, the right colon and ileum were used for the reconstruction, and a cervical esophago-ileostomy and an abdominal colo-duodenostomy were made in the fashion of an interposition.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Esophageal Neoplasms / surgery. Esophagectomy. Gastrectomy. Gastric Stump / surgery. Neoplasms, Multiple Primary / surgery. Pancreaticoduodenectomy. Postoperative Complications / surgery
  • [MeSH-minor] Adenoma / surgery. Humans. Lymph Node Excision. Middle Aged. Neoplasm Invasiveness. Reoperation. Stomach Neoplasms / surgery

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  • (PMID = 15966235.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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93. Nakagoe T, Sawai T, Tsuji T, Tanaka K, Nanashima A, Shibasaki S, Yamaguchi H, Yasutake T, Ayabe Y: Laparotomy wound and anastomotic recurrences after resection for cecum cancer: a case report. Hepatogastroenterology; 2007 Oct-Nov;54(79):2037-9

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  • Intestinal reconstruction had been performed by stapled functional end-to-end anastomosis between the ileum and ascending colon.
  • [MeSH-major] Adenocarcinoma / surgery. Cecal Neoplasms / surgery. Laparotomy. Neoplasm Recurrence, Local / etiology
  • [MeSH-minor] Anastomosis, Surgical. Humans. Male. Middle Aged. Neoplasm Seeding. Recurrence. Surgical Staplers. Surgical Stapling

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  • (PMID = 18251155.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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94. Schwartz GD, Barkin JS: Small-bowel tumors detected by wireless capsule endoscopy. Dig Dis Sci; 2007 Apr;52(4):1026-30

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  • [Title] Small-bowel tumors detected by wireless capsule endoscopy.
  • Small bowel tumors are difficult to diagnose because of their endoscopic inaccessibility.
  • The purpose of this report is to describe the largest series of patients with small bowel tumors detected by capsule endoscopy.
  • Eighty six patients were derived from the Given Imaging clinical database on a survey of Pillcam SB capsule users who were diagnosed with 87 small bowel tumors, 1 cecal tumor, and 1 gastric tumor.
  • Malignant tumors comprised 61% (54/89) and benign 39% (35/89).
  • Of the 87 reported small bowel tumors, 4 were identified in the duodenum, 43 tumors were identified in the jejunum, 18 tumors were identified in the ileum, and 22 tumors were located in the mid to distal small bowel.
  • The most common malignant tumors were adenocarcinoma, carcinoids, melanomas, lymphomas, and sarcomas.
  • Capsule endoscopy is the diagnostic procedure of choice in patients with suspected small bowel tumors.
  • [MeSH-major] Capsule Endoscopy. Endoscopy, Gastrointestinal. Intestinal Neoplasms / diagnosis. Intestine, Small

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  • (PMID = 17380403.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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95. Rosati G, Ugolini G, Senatore G, Leone Ornella O, Montroni I, Zanotti S, Manaresi A, Taffurelli M: Sarcomatoid anaplastic carcinoma of the small bowel in cardiac transplant bearer. Minerva Chir; 2008 Aug;63(4):301-6
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  • [Title] Sarcomatoid anaplastic carcinoma of the small bowel in cardiac transplant bearer.
  • Sarcomatoid carcinoma is a rare form of primitive carcinoma of the small bowel; it is considered a variant of adenocarcinoma, histologically characterized by a typical biphasic pattern with epithelial- and mesenchymal-like cells.
  • Twenty-one cases have been described in the literature, presenting as small bowel obstructions (twenty cases) or superior vena cava syndrome (one case).
  • The operation brought to light an intraluminal occlusive mass in the distal ileum, associated with other intraluminal neoplasms of different sizes throughout the small bowel.
  • Early diagnosis is usually very difficult, due to the lack of any stereotyped clinical expression and the difficult to study the small bowel.
  • Small-bowel barium follow-through or video capsule endoscopy can be helpful.
  • In most cases, an emergency surgical operation is performed without a clear preoperative diagnosis.

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  • (PMID = 18607327.001).
  • [ISSN] 0026-4733
  • [Journal-full-title] Minerva chirurgica
  • [ISO-abbreviation] Minerva Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 21
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96. Bennett VS, Bailey DM: Cholangiocarcinoma presenting as a solitary epididymal metastasis: a case report and review of the literature. Diagn Pathol; 2007;2:33

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  • Other primary carcinomas that have been demonstrated to metastasize to the paratesticular region include those originating in the stomach, kidney, ileum, and colon.
  • Computed tomography of the abdomen demonstrated an obstructive stricture of the extra-hepatic bile ducts, in keeping with a cholangiocarcinoma, through which a metal stent was endoscopically inserted for symptomatic relief.Subsequent right radical orchidectomy yielded a diffusely infiltrative adenocarcinoma obliterating the epididymis, extending into the rete testis, vas deferens and spermatic cord and showing widespread vascular and perineural invasion.

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  • (PMID = 17760973.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2000863
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97. Mohamud SO, Motorwala SA, Daniel AR, Tworek JA, Shehab TM: Giant ileal inflammatory fibroid polyp causing small bowel obstruction: a case report and review of the literature. Cases J; 2008;1(1):341

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  • [Title] Giant ileal inflammatory fibroid polyp causing small bowel obstruction: a case report and review of the literature.
  • INTRODUCTION: There are several types of small bowel pathology that can lead to small bowel obstruction or intussusception.
  • The etiology causing small bowel obstruction varies by age.
  • Benign disease is the typical cause in children and adolescents while malignant or adhesive disease is far more common in older patients.
  • Although cases of adult intussusception caused by benign processes are rare, there are reports of inflammatory fibroid polyps causing adult intussusception of the terminal ileum published in the literature.
  • CASE PRESENTATION: We present the case of a 70-year-old man with a multiple year history of intermittent episodes of bowel obstruction who was found to have a giant ileal inflammatory fibroid polyp causing intermittent small bowel obstruction.
  • CONCLUSION: Small bowel lesions include both malignant and benign etiologies.
  • The malignant etiologies include adenocarcinoma, carcinoid or lymphoma while benign lesions are typically lipomas, inflammatory polyps or adenomas.

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  • (PMID = 19025593.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2596112
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98. Lakyová L, Toporcer T, Bober J, Radonak J: [A rare complication following anastomosis suturing using a biofragmentable Valtrac anastomosis ring--a case review and literature overview]. Rozhl Chir; 2010 Aug;89(7):446-9
Hazardous Substances Data Bank. Barium sulfate .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 67 year old patient, after right hemicolectomy with ileotransversoanastomosis with the help of Valtrac due to adenocarcinoma, underwent a control colonoscopy six month after operation.
  • Small polyps in colon sigmoideum, colon descendens and transverse were removed and a tissue stripe with ulceration was found during the examination.
  • [MeSH-major] Anastomosis, Surgical / adverse effects. Barium Sulfate / adverse effects. Ileum / surgery. Polyglycolic Acid / adverse effects

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  • (PMID = 20925262.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] slo
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Valtrac; 25BB7EKE2E / Barium Sulfate; 26009-03-0 / Polyglycolic Acid
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99. Shukla S, Singh SK, Pujani M: Multicentric malignant gastrointestinal stromal tumor. Saudi J Gastroenterol; 2009 Jan;15(1):45-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multicentric malignant gastrointestinal stromal tumor.
  • Malignant gastrointestinal stromal tumor (GIST) is a rare type of sarcoma that is found in the digestive system, most often in the wall of the stomach.
  • Ultrasound examination showed a small bowel mass along with multiple peritoneal deposits and a mass within the liver.
  • Barium studies were suggestive of a neoplastic pathology of the distal ileum.
  • A differential diagnosis of adenocarcinoma/lymphoma with metastases was entertained.
  • Perioperative findings showed two large growths arising from the jejunum and the distal ileum, along with multiple smaller nodules on the serosal surface and adjoining mesentery of the involved bowel segments.
  • Segmental resection of the involved portions of the intestine was performed.
  • Histopathological features were consistent with those of multicentric malignant GIST-not otherwise specified (GIST-NOS).

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  • (PMID = 19568556.001).
  • [ISSN] 1319-3767
  • [Journal-full-title] Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
  • [ISO-abbreviation] Saudi J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Other-IDs] NLM/ PMC2702961
  • [Keywords] NOTNLM ; GIST / malignant / multicentric
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100. Fujitani K, Ogawa H, Takeda M, Hirao M, Yasui M, Kashiwazaki M, Ikenaga M, Miyazaki M, Mishima H, Nakamori S, Manoh M, Tsujinaka T: [A case report of pseudomyxoma peritonei demonstrating complete response after intensive therapy consisting of cytoreductive surgery and adjuvant chemotherapy with paclitaxel and S-1]. Gan To Kagaku Ryoho; 2008 Mar;35(3):523-7
Hazardous Substances Data Bank. TAXOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pathology revealed mucinous adenocarcinoma with low-grade malignancy originating in the appendix with disseminated peritoneal adenomucinosis, which was diagnostic of pseudomyxoma peritonei.
  • A follow-up computed tomography (CT) scan revealed small ascites only in the right pelvis 8 months later after the initial operation, and complete disappearance of ascites 17 months later.
  • Two years later, the patient presented with ileus, and required adhesionlysis as well as partial resection of adhesive ileum.

  • Genetic Alliance. consumer health - Pseudomyxoma peritonei.
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  • (PMID = 18347410.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; P88XT4IS4D / Paclitaxel
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