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[Title] Extraskeletal Ewing's sarcoma of the head and neck presenting as blindness.

Extraskeletal Ewing's sarcoma is rarely found in the head and neck regions.

The final diagnosis was extraskeletal Ewing's sarcoma after biopsy of the internal jugular vein thrombosis by histopathological evaluation and immunohistochemical assay.

In addition, the patient was diagnosed as having adenocarcinoma of the rectum by biopsy of the rectal mass.

[MeSH-major] Blindness. Head and Neck Neoplasms / pathology. Sarcoma, Ewing / pathology

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(PMID = 17616033.001).

[ISSN] 1226-3303

[Journal-full-title] The Korean journal of internal medicine

[ISO-abbreviation] Korean J. Intern. Med.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Korea (South)

[Chemical-registry-number] 0 / Antineoplastic Agents; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide

[Other-IDs] NLM/ PMC2687615

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Human papillomavirus seropositivity and risks of head and neck cancer.

We examined antibody response to VLP HPV-16, HPV-16 E6 and E7 antibodies as potential seromarkers of HPV-related head and neck cancer (HNC).

[MeSH-major] Antibodies, Viral / blood. DNA-Binding Proteins / immunology. Head and Neck Neoplasms / virology. Oncogene Proteins, Viral / immunology. Papillomaviridae / immunology. Papillomavirus Infections / virology

[MeSH-minor] Adenocarcinoma / etiology. Alcohol Drinking. Carcinoma, Mucoepidermoid / etiology. Case-Control Studies. DNA, Viral / analysis. Enzyme-Linked Immunosorbent Assay. Female. Humans. Male. Middle Aged. Risk Factors

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(PMID = 17131312.001).

[ISSN] 0020-7136

[Journal-full-title] International journal of cancer

[ISO-abbreviation] Int. J. Cancer

[Language] eng

[Grant] United States / NIDCR NIH HHS / DE / DE1311-S1; United States / NIDCR NIH HHS / DE / DE13110; United States / FIC NIH HHS / TW / TW01500

[Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

[Publication-country] United States

[Chemical-registry-number] 0 / Antibodies, Viral; 0 / DNA, Viral; 0 / DNA-Binding Proteins; 0 / E2 protein, Human papillomavirus type 16; 0 / E6 protein, Human papillomavirus type 18; 0 / Oncogene Proteins, Viral

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Chromosomal radiosensitivity in head and neck cancer patients: evidence for genetic predisposition?

The association between chromosomal radiosensitivity and genetic predisposition to head and neck cancer was investigated in this study.

In all, 101 head and neck cancer patients and 75 healthy control individuals were included in the study.

The results demonstrated that head and neck cancer patients had a statistically higher number of radiation-induced chromatid breaks than controls, with mean values of 1.23 and 1.10 breaks per cell, respectively (P<0.001).

In conclusion, enhanced chromosomal radiosensitivity is a marker of genetic predisposition to head and neck cancer, and the genetic contribution is highest for oral cavity and pharynx cancer patients and for early onset and non- and light smoking patients.

[MeSH-major] Chromosomes, Human / radiation effects. G2 Phase / radiation effects. Head and Neck Neoplasms / genetics. Smoking / adverse effects

[MeSH-minor] Adenocarcinoma / genetics. Adult. Age Factors. Aged. Carcinoma, Squamous Cell / genetics. Chromatids / radiation effects. DNA Damage / radiation effects. DNA Repair / radiation effects. DNA, Neoplasm. Female. Genetic Markers. Genetic Predisposition to Disease. Humans. Laryngeal Neoplasms / genetics. Logistic Models. Male. Middle Aged. Mouth Neoplasms / genetics. Odds Ratio. Pharyngeal Neoplasms / genetics. Risk Factors

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(PMID = 18414410.001).

[ISSN] 1532-1827

[Journal-full-title] British journal of cancer

[ISO-abbreviation] Br. J. Cancer

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Genetic Markers

[Other-IDs] NLM/ PMC2391130

   

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[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Molecular diagnosis in head and neck: what a surgical pathologist must know.

In the head and neck, there are a variety of different alterations, encompassing all the different types of genetic events associated with carcinogenesis.

[MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / genetics. Clinical Competence. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / genetics. Pathology, Surgical / education

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(PMID = 20614331.001).

[ISSN] 1936-0568

[Journal-full-title] Head and neck pathology

[ISO-abbreviation] Head Neck Pathol

[Language] eng

[Publication-type] Congresses

[Publication-country] United States

[Chemical-registry-number] 0 / CDC73 protein, human; 0 / DNA, Viral; 0 / Tumor Suppressor Proteins

[Other-IDs] NLM/ PMC2807553

[Keywords] NOTNLM ; Lymphoepithelial carcinoma / Mucoepidermoid carcinoma / Nasopharyngeal carcinoma / Parathyroid carcinoma / Tumor markers

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Diagnosis and management of neck metastases from an unknown primary.

Neck lymph node metastases from occult primary constitute about 5%-10% of all patients with carcinoma of unknown primary site.

Metastases in the upper and middle neck (levels I-II-III-V) are generally attributed to head and neck cancers, whereas the lower neck (level IV) involvement is often associated with primaries below the clavicles.

Diagnostic procedures include a careful clinical evaluation and a fiberoptic endoscopic examination of the head and neck mucosa, biopsies from all suspicious sites or blindly from the sites of possible origin of the primary, computerized tomography scan, and magnetic resonance.

The most frequent histological finding is Squamous Cell Carcinoma, particularly when the upper neck is involved.

In these cases, a systematic tonsillectomy in the absence of suspicious lesions is discussed since up to 25% of primary tumours can be detected in this site.

Thoracic, and abdominal primaries (especially from lung, oesophagus, stomach, ovary or pancreas) should be sought in the case of adenocarcinoma and involvement of the lower neck.

Therapeutic approaches include surgery (neck dissection), with or without post-operative radiotherapy, radiotherapy alone and radiotherapy followed by surgery as reported by several guide-lines.

In early stages (N1), neck dissection and radiotherapy seem to have similar efficacy, whereas more advanced cases (N2, N3) require combined approaches.

The extent of radiotherapy (irradiation of bilateral neck and mucosa versus ipsilateral neck radiotherapy) remains debatable.

[MeSH-major] Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / secondary. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / secondary. Neoplasms, Unknown Primary

[MeSH-minor] Aged. Follow-Up Studies. Humans. Middle Aged. Neoplasm Staging

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(PMID = 16080309.001).

[ISSN] 0392-100X

[Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale

[ISO-abbreviation] Acta Otorhinolaryngol Ital

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] Italy

[Number-of-references] 102

[Other-IDs] NLM/ PMC2639847

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Diagnosis and treatment of a neck node swelling suspicious for a malignancy: an algorithmic approach.

Aim. To present an up-to-date algorithm incorporating recent advances regarding its diagnosis and treatment.

The vast majority of neck nodes from occult primaries (>90%) represent SCC with a high incidence among middle aged man.

Asiatic and North African patients with neck node metastases are at risk of harbouring an occult nasopharyngeal carcinoma.

The remainder are adenocarcinoma, undifferentiated carcinoma, melanoma, thyroid carcinoma and Merkel cell carcinoma.

FDG-PET/CT has proven to be helpful in identifying occult primary carcinomas of the head and neck, especially when applied as a guiding tool prior to panendoscopy, and may induce treatment related clinical decisions in up to 60% of cases.

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(PMID = 22312490.001).

[ISSN] 2090-1402

[Journal-full-title] International journal of surgical oncology

[ISO-abbreviation] Int J Surg Oncol

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC3265261

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Distant metastases to nasal cavities and paranasal sinuses, from the organs outside the head and neck].

INTRODUCTION: The metastases from below the clavicles, to the head and neck region, are relatively uncommon, and usually demonstrate during the progression of the primary disease.

At that time, the correct diagnosis requires only to compare the pathology report from the primary biopsy, with the biopsy from the lump in the head and neck.

The majority of distant metastases to the head and neck region are localized within the lymph nodes.

MATERIAL: 4 cases, out of 46 all distant metastases to the head and neck region, localized in the nasal cavity and paranasal sinuses, diagnosed and treated in Dept. of ORL H&N surgery, Holy Cross Cancer Centre, from 2001 to 2007.

The palliative Rtg-therapy was applied, and patient died in 2 months after diagnosis was established.

At present with no metastasis within the head and neck region--alive, in relatively good condition, with 23 months of observation.

Died in 5 months after diagnosis of maxillary sinus metastasis.

Died in 18 months, after diagnosis of maxillary sinus metastasis.

[MeSH-major] Adenocarcinoma / pathology. Breast Neoplasms / pathology. Carcinoma, Renal Cell / pathology. Colonic Neoplasms / pathology. Paranasal Sinus Neoplasms / secondary. Skull Base Neoplasms / secondary

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(PMID = 18837216.001).

[ISSN] 0030-6657

[Journal-full-title] Otolaryngologia polska = The Polish otolaryngology

[ISO-abbreviation] Otolaryngol Pol

[Language] pol

[Publication-type] English Abstract; Journal Article

[Publication-country] Poland

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Three cases of adenocarcinoma of the head and neck maintaining QOL by administration of docetaxel].

A primary head and neck adenocarcinoma is a comparatively rare disease, and surgical resection has been the first choice for its treatment.

In the present study, we performed chemotherapy with weekly administration of docetaxel in 3 cases with unresectable or recurrent adenocarcinoma of the head and neck on an outpatient basis, resulting in long-term maintenance of the patients' QOL.

The present results might suggest that it is possible to treat patients with adenocarcinoma in the head and neck without decreasing patients' QOL.

[MeSH-major] Adenocarcinoma / drug therapy. Head and Neck Neoplasms / drug therapy. Taxoids / administration & dosage

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(PMID = 21160265.001).

[ISSN] 0385-0684

[Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy

[ISO-abbreviation] Gan To Kagaku Ryoho

[Language] jpn

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Japan

[Chemical-registry-number] 0 / Taxoids; 15H5577CQD / docetaxel

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Three cases of bilateral chylothorax developing after neck dissection.

Only 16 cases of bilateral chylothorax following neck dissection have been reported within 10 decades.

In this paper, three cases of bilateral chylothorax which developed after neck dissection are reported.

Diagnosis may be delayed in those who are on total parenteral nutrition, and therefore particular attention should be paid to those patients.

It may be difficult to treat cases of chylothorax that develop following neck dissection performed after radiotherapy.

[MeSH-major] Adenocarcinoma, Papillary / surgery. Chylothorax / etiology. Laryngeal Neoplasms / surgery. Neck Dissection / adverse effects. Postoperative Complications / etiology. Thyroid Neoplasms / surgery. Tongue Neoplasms / surgery

[MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Ligation. Male. Middle Aged. Neoplasm Staging. Parenteral Nutrition, Total. Thoracic Duct / surgery. Thoracostomy

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(PMID = 17466474.001).

[ISSN] 0385-8146

[Journal-full-title] Auris, nasus, larynx

[ISO-abbreviation] Auris Nasus Larynx

[Language] eng

[Publication-type] Case Reports; Journal Article; Review

[Publication-country] Netherlands

[Number-of-references] 20

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Occult primary head and neck carcinoma.

Unknown primary carcinoma presenting as cervical lymph node metastasis accounts for approximately 5% of all head and neck malignancies.

The typical presentation involves a middle-aged man with a painless neck mass that has been present for several months.

The remainder are comprised of adenocarcinoma, melanoma, and other rare histologic variants.

The ability to identify the occult primary tumor is imperative because identification allows site-specific therapy and avoidance of wide-field radiation side effects.

Following confirmation of metastatic cervical disease with fine-needle aspiration, all patients presenting with an unknown primary carcinoma require a thorough head and neck history and physical examination, radiographic imaging, panendoscopy with directed biopsies of Waldeyer's ring, and bilateral tonsillectomy.

Positron emission tomography has proved helpful in identifying occult primary tumors of the head and neck region.

[MeSH-major] Head and Neck Neoplasms / secondary. Neoplasms, Unknown Primary / pathology

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[Cites] Eur J Cancer. 2003 Sep;39(14):1990-2005 [12957453.001]

[Cites] Arch Otolaryngol Head Neck Surg. 2002 Jun;128(6):703-7 [12049568.001]

[Cites] Br J Cancer. 2002 Feb 12;86(4):512-6 [11870529.001]

[Cites] Cancer. 2005 Aug 1;104(3):570-9 [15977211.001]

[Cites] Laryngoscope. 2002 Jun;112(6):1010-4 [12160265.001]

[Cites] J Nucl Med. 2004 Jan;45(1):56-68 [14734674.001]

[Cites] Laryngoscope. 1992 Aug;102(8):884-90 [1495353.001]

[Cites] Head Neck. 1998 Dec;20(8):674-81 [9790287.001]

[Cites] Head Neck. 2005 Aug;27(8):729-32 [15920751.001]

[Cites] Eur J Nucl Med Mol Imaging. 2005 May;32(5):589-92 [15726356.001]

[Cites] Laryngoscope. 2001 Jul;111(7):1209-22 [11568543.001]

[Cites] Head Neck. 2004 Feb;26(2):171-8 [14762886.001]

[Cites] Head Neck. 1998 Dec;20(8):739-44 [9790297.001]

[Cites] Arch Otolaryngol Head Neck Surg. 2005 Jul;131(7):626-9 [16027287.001]

[Cites] Otolaryngol Head Neck Surg. 2000 Sep;123(3):294-301 [10964310.001]

[Cites] N Engl J Med. 2004 May 6;350(19):1937-44 [15128893.001]

[Cites] Laryngoscope. 2005 Nov;115(11):2029-34 [16319618.001]

[Cites] Int J Oral Maxillofac Surg. 1997 Apr;26(2):112-5 [9151165.001]

[Cites] Curr Probl Surg. 2005 Jan;42(1):12-66 [15711508.001]

[Cites] Head Neck. 2002 Mar;24(3):236-46 [11891955.001]

[Cites] Int J Radiat Oncol Biol Phys. 1992;23(4):743-9 [1618667.001]

[Cites] Head Neck. 2003 Jun;25(6):499-504 [12784242.001]

[Cites] Dermatol Ther. 2005 Nov-Dec;18(6):413-21 [16297017.001]

[Cites] J Am Coll Surg. 2001 Dec;193(6):666-77 [11768684.001]

[Cites] Laryngoscope. 2005 Nov;115(11):1979-82 [16319609.001]

[Cites] Head Neck. 1990 Nov-Dec;12(6):463-9 [2258284.001]

(PMID = 17288881.001).

[ISSN] 1523-3790

[Journal-full-title] Current oncology reports

[ISO-abbreviation] Curr Oncol Rep

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] United States

[Number-of-references] 27

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Adenocarcinoma ex pleomorphic adenoma of the head and neck: Report of five cases.

OBJECTIVE: Adenocarcinoma ex pleomorphic adenoma is a rare tumor, and thus the management of the tumor has not been established.

RESULTS: We present five cases of adenocarcinoma ex pleomorphic adenoma of the head and neck, including a rare case with nasopharyngeal adenocarcinoma ex pleomorphic adenoma.

There was no response to chemotherapy with nedaplatin and 5-FU, but the nasopharyngeal adenocarcinoma ex pleomorphic adenoma showed a remarkable regression after the administration of docetaxel.

CONCLUSION: The combination therapy that includes docetaxel may be a promising treatment for adenocarcinoma ex pleomorphic adenoma of the head and neck.

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(PMID = 16168590.001).

[ISSN] 0385-8146

[Journal-full-title] Auris, nasus, larynx

[ISO-abbreviation] Auris Nasus Larynx

[Language] eng

[Publication-type] Journal Article

[Publication-country] Netherlands

[Chemical-registry-number] 0 / Organoplatinum Compounds; 0 / Taxoids; 15H5577CQD / docetaxel; 8UQ3W6JXAN / nedaplatin; U3P01618RT / Fluorouracil

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Versatility of free SCIA/SIEA flaps in head and neck defects.

Reconstruction of head and neck defects may require replacement of the bony structures, external soft tissue, and intraoral mucosa.

Recently, the authors used free superficial circumflex iliac artery/superficial inferior epigastric (SCIA/SIEA) flaps for head and neck reconstruction.

Fifteen patients underwent head and neck reconstruction with free SCIA/SIEA flaps (n = 16).

Based on our results, we believe that the free SCIA/SIEA flap is useful for soft tissue defect reconstruction in the head and neck.

(1) Large flap elevation is possible for reaching distant recipient vessels, (2) Two surgical teams may work at the same time preparing the donor and recipient regions, and (3) The flap design uses an abdominoplasty incision, which has minimal donor site morbidity.

[MeSH-minor] Adenocarcinoma / surgery. Adolescent. Adult. Aged. Bone Transplantation. Burns / surgery. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Child. Cicatrix / surgery. Facial Neoplasms / surgery. Female. Follow-Up Studies. Humans. Male. Maxilla / surgery. Maxillary Neoplasms / surgery. Middle Aged. Neck Injuries / surgery. Neoplasm Recurrence, Local / surgery. Reoperation. Scalp / surgery. Skin Neoplasms / surgery. Young Adult

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(PMID = 20574218.001).

[ISSN] 1536-3708

[Journal-full-title] Annals of plastic surgery

[ISO-abbreviation] Ann Plast Surg

[Language] eng

[Publication-type] Case Reports; Comparative Study; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Pulmonary resection for metastatic head and neck cancer.

BACKGROUND: Pulmonary metastasectomy has become the standard therapy for various metastatic malignancies to the lungs; however, little data have been available about lung metastasectomy for head and neck cancers.

METHODS: Between 1991 and 2007, 20 patients with pulmonary metastases from head and neck cancers underwent complete pulmonary resection.

All patients had obtained or had obtainable locoregional control of their primary head and neck cancers.

The median disease-free interval from the time of treatment of the head and neck primary cancers to the development of pulmonary metastases was 27 months.

CONCLUSION: The current practice of pulmonary metastasectomy for head and neck cancers in our institution was well justified.

[MeSH-major] Adenocarcinoma / secondary. Adenocarcinoma / surgery. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Head and Neck Neoplasms / pathology. Lung Neoplasms / secondary. Lung Neoplasms / surgery

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[Cites] Semin Oncol. 2007 Jun;34(3):186-96 [17560980.001]

[Cites] Am J Surg. 1992 Dec;164(6):594-8 [1463106.001]

[Cites] Arch Otolaryngol Head Neck Surg. 1994 Jul;120(7):721-6 [8018324.001]

[Cites] Oral Oncol. 2005 Oct;41(9):890-4 [16043380.001]

[Cites] Head Neck. 2002 Aug;24(8):779-83 [12203804.001]

[Cites] Semin Thorac Cardiovasc Surg. 2003 Oct;15(4):457-63 [14710388.001]

[Cites] Laryngoscope. 1994 Oct;104(10):1199-205 [7934588.001]

[Cites] Semin Thorac Cardiovasc Surg. 2002 Jan;14(1):18-28 [11977013.001]

[Cites] Am J Surg. 1988 Oct;156(4):238-42 [2845826.001]

[Cites] Am J Otolaryngol. 1997 Nov-Dec;18(6):391-5 [9395015.001]

[Cites] Semin Surg Oncol. 1990;6(5):297-302 [2237090.001]

[Cites] Ann Surg Oncol. 1999 Sep;6(6):572-8 [10493626.001]

[Cites] Cancer. 1984 Jan 15;53(2):342-5 [6690016.001]

[Cites] Am J Surg. 1997 Nov;174(5):499-502 [9374224.001]

[Cites] Head Neck. 1996 Jul-Aug;18(4):311-6 [8780941.001]

(PMID = 18553194.001).

[ISSN] 0364-2313

[Journal-full-title] World journal of surgery

[ISO-abbreviation] World J Surg

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Microimaging FTIR of head and neck tumors. IV.

On continuing our studies on head and neck neoplasia, specimens from salivary gland tumors have been explored by using infrared microimaging spectroscopy to discern healthy from neoplastic tissues.

Samples with Warthin tumor, epithelial displasia, marginal B-cell lymphoma, low-grade adenocarcinoma, and adenoid cystic carcinoma pathologies have been investigated by using conventional light sources.

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[Copyright] (c) 2008 Wiley-Liss, Inc.

(PMID = 18825780.001).

[ISSN] 1097-0029

[Journal-full-title] Microscopy research and technique

[ISO-abbreviation] Microsc. Res. Tech.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Photodynamic therapy of head and neck cancers.

Over 1,500 patients have been treated with PDT using Photofrin, HPD, ALA, or Foscan for head and neck cancers.

The predominant histology is squamous cell carcinoma, but other histologies treated include mucosal melanoma, Kaposi's sarcoma, adenocarcinoma, metastatic breast carcinoma, and adenoid cystic carcinoma.

Several multi-institutional phase II clinical trials evaluating PDT treatment of head and neck cancers have demonstrated the efficacy of this minimally invasive therapy in the treatment of early oropharyngeal primary and recurrent cancers as well as the palliative treatment of refractory head and neck cancers.

Photodynamic therapy is as effective as conventional therapies for the treatment of early (Cis, T1, T2) squamous cell cancers of the head and neck.

[MeSH-major] Head and Neck Neoplasms / drug therapy. Photochemotherapy

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(PMID = 20552353.001).

[ISSN] 1940-6029

[Journal-full-title] Methods in molecular biology (Clifton, N.J.)

[ISO-abbreviation] Methods Mol. Biol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] How we do it: Chemo-electroporation in the head and neck for otherwise untreatable patients.

Keypoints * Chemo-electroporation therapy with bleomycin is a locoregional treatment modality for head and neck and skin cancer, with the potential to preserve function.

* Based on the outcome of the clinical trial, bleomycin-electroporation therapy has the potential to become a valuable addition to the late-stage treatment options for patients with head and neck or skin tumours.

[MeSH-major] Antibiotics, Antineoplastic / therapeutic use. Bleomycin / therapeutic use. Electroporation / methods. Head and Neck Neoplasms / therapy

[MeSH-minor] Adenocarcinoma / secondary. Adenocarcinoma / therapy. Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / secondary. Carcinoma, Basal Cell / therapy. Carcinoma, Merkel Cell / secondary. Carcinoma, Merkel Cell / therapy. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / therapy. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Melanoma / secondary. Melanoma / therapy. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Netherlands. Salivary Gland Neoplasms / secondary. Salivary Gland Neoplasms / therapy. Sarcoma / secondary. Sarcoma / therapy. Skin Neoplasms / secondary. Skin Neoplasms / therapy. Treatment Outcome. Tumor Burden / drug effects

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(PMID = 17014460.001).

[ISSN] 1749-4478

[Journal-full-title] Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

[ISO-abbreviation] Clin Otolaryngol

[Language] eng

[Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 11056-06-7 / Bleomycin

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Unilateral neck mass, dysphagia and dyspnea].

Extraocular sebaceous carcinoma is a rare malignant tumor, arising from skin and salivary glands.

An important differential diagnosis in the head and neck region is metastasizing squamous cell carcinoma.

[MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Deglutition Disorders / etiology. Dyspnea / etiology. Head and Neck Neoplasms / diagnosis. Hypopharyngeal Neoplasms / diagnosis. Sebaceous Gland Neoplasms / diagnosis

[MeSH-minor] Biomarkers, Tumor / analysis. Biopsy. Diagnosis, Differential. Endoscopy. Humans. Keratin-5 / analysis. Male. Pyriform Sinus / pathology. Pyriform Sinus / surgery. Surgical Flaps. Tomography, X-Ray Computed. Tracheotomy. Ultrasonography

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[Cites] Hautarzt. 2001 Feb;52(2):147-9 [11244894.001]

[Cites] Br J Dermatol. 2003 Aug;149(2):441-2 [12932271.001]

[Cites] Arch Otolaryngol Head Neck Surg. 1992 Nov;118(11):1245-9 [1418905.001]

[Cites] Diagn Cytopathol. 2004 Nov;31(5):326-9 [15468126.001]

(PMID = 20694546.001).

[ISSN] 1433-0458

[Journal-full-title] HNO

[ISO-abbreviation] HNO

[Language] ger

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Germany

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-5

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

: 4570 Background: Cetuximab significantly enhances efficacy of radiotherapy and chemotherapy in head and neck cancer.

METHODS: Pts with resectable, locally advanced squamous cell carcinoma (SCC) or adenocarcinoma (AC) of the thoracic esophagus or gastroesophageal junction (staged by EUS, CT and PET scan) were treated with 2 cycles of induction chemotherapy (docetaxel 75mg/m2, cisplatin 75mg/m2 q3w and weekly cetuximab 250mg/m2), followed by concomitant chemo- immuno-radiation therapy (CIRT: docetaxel 20mg/m2, cisplatin 25mg/m2 and cetuximab 250mg/m2 weekly five times concomitant with 45 Gy radiotherapy in 25 fractions); followed by surgery 4-8 weeks later.

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(PMID = 27963079.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

RESULTS: Patient characteristics: male 11/female 10; median age 59 (range 28-84); performance status 0 /1/2: n=1/13/7; prior chemotherapy 21, prior radiotherapy 7, prior immunotherapy 1; tumour types: ovarian cancer 3, endometrial cancer 3, NSCLC 3, gastric/esophageal adenocarcinoma 3, miscellaneous 9.

RESPONSE: partial response 1 (ovarian cancer), stable 8 [minor response 4 (NSCLC 2, endometrial cancer 1, head and neck cancer 1)], progression 8, inevaluable 4.

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(PMID = 27961270.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Clinicopathological features of head and neck adenosquamous carcinoma.

Adenosquamous carcinoma is a rare tumour which is characterized pathologically by the simultaneous presence of distinct areas of squamous cell carcinoma and adenocarcinoma.

In the present study, the medical and pathological records of 4 patients with head and neck adenosquamous carcinoma are reviewed.

[MeSH-major] Carcinoma, Adenosquamous / pathology. Head and Neck Neoplasms / pathology

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[Copyright] Copyright (c) 2005 S. Karger AG, Basel.

(PMID = 15637416.001).

[ISSN] 0301-1569

[Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties

[ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Switzerland

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Resection of secondary pulmonary malignancies in head and neck cancer patients.

BACKGROUND: This study aimed to evaluate a single institute's experience with resection of metachronous pulmonary malignancy in patients treated for squamous cell carcinoma of the head and neck.

METHODS: Sixty-three consecutive patients treated curatively for head and neck squamous cell carcinoma underwent surgical resection of malignant lung lesions.

For patients with pulmonary squamous cell carcinoma (n = 52), the three-year survival rate was 35 per cent (95 per cent confidence interval, 22-48); for patients with resected adenocarcinoma (n = 10), it was 50 per cent (95 per cent confidence interval, 18-75).

CONCLUSION: In patients treated curatively for head and neck squamous cell carcinoma, resection of secondary pulmonary cancer is associated with favourable long term overall survival, especially for patients with adenocarcinoma lesions.

[MeSH-major] Carcinoma, Squamous Cell / surgery. Head and Neck Neoplasms / surgery. Lung Neoplasms / surgery. Neoplasms, Second Primary / surgery

[MeSH-minor] Adenocarcinoma / mortality. Adenocarcinoma / surgery. Adult. Aged. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Prognosis. Survival Rate. Treatment Outcome

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(PMID = 20519045.001).

[ISSN] 1748-5460

[Journal-full-title] The Journal of laryngology and otology

[ISO-abbreviation] J Laryngol Otol

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Chemical-registry-number] Adenocarcinoma of lung

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Salvage high-dose-rate (HDR) brachytherapy for recurrent head-and-neck cancer.

BACKGROUND: A significant portion of head-and-neck cancer patients will develop persistent or recurrent disease after definitive treatment.

Recurrent cancer of the head and neck in the previously irradiated field is, thus, a common occurrence and poses a therapeutic challenge.

This study evaluates the local control and outcomes of patients with previously irradiated recurrent head-and-neck cancer treated with HDR interstitial brachytherapy.

METHODS AND MATERIALS: Between 1997 and 2002, 30 patients who received prior radiation therapy for primary tumors of the head and neck were treated for biopsy-proven recurrent disease.

CONCLUSION: HDR brachytherapy can play an important role in the salvage treatment of previously irradiated recurrent head-and-neck cancer.

[MeSH-major] Brachytherapy / methods. Head and Neck Neoplasms / radiotherapy. Neoplasm Recurrence, Local / radiotherapy. Salvage Therapy / methods

[MeSH-minor] Adenocarcinoma / radiotherapy. Carcinoma, Mucoepidermoid / radiotherapy. Carcinoma, Squamous Cell / radiotherapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Radiotherapy Dosage. Survival Analysis

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(PMID = 16029806.001).

[ISSN] 0360-3016

[Journal-full-title] International journal of radiation oncology, biology, physics

[ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.

[Language] eng

[Publication-type] Evaluation Studies; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Microvascular free-tissue transfer for head and neck reconstruction in Jehovah's Witness patients.

The objective of this study is to describe our experience with microvascular reconstruction of complex head and neck defects in Jehovah's Witness patients.

METHODS: This was a retrospective review of all Jehovah's Witnesses' patients undergoing head and neck free-flap reconstruction at a tertiary academic referral center from 1997 to 2006.

CONCLUSIONS: Our case series supports the feasibility of head and neck free-flap reconstruction in these challenging patients.

[MeSH-major] Head and Neck Neoplasms / surgery. Jehovah's Witnesses. Surgical Flaps

[MeSH-minor] Adenocarcinoma / surgery. Aged. Carcinoma, Squamous Cell / surgery. Carotid Artery, External. Embolization, Therapeutic. Erythropoietin / therapeutic use. Female. Ferrous Compounds / therapeutic use. Hematocrit. Humans. Male. Microsurgery. Middle Aged. Perioperative Care. Preoperative Care. Retrospective Studies. Treatment Outcome

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(PMID = 18098311.001).

[ISSN] 1043-3074

[Journal-full-title] Head & neck

[ISO-abbreviation] Head Neck

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Ferrous Compounds; 11096-26-7 / Erythropoietin; 39R4TAN1VT / ferrous sulfate

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Breast cancer metastases in the head and neck region].

Breast cancer metastases to the head and neck region are very rare and therefore represent a challenge for the clinician in terms of diagnosis and therapy.

Diagnosis, therapy and distinctive features of metastasis to the head and neck region are discussed.Secondary to long-term endocrine hormone therapy, a reduction in estrogen receptor expression occurred in all three cases.

Moreover, this receptor loss hindered the pathologist from confirming the diagnosis of metastases at very unusual sites.

[MeSH-major] Breast Neoplasms / diagnosis. Carcinoma, Ductal / secondary. Laryngeal Neoplasms / secondary. Petrous Bone. Skull Neoplasms / secondary

[MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / therapy. Aged. Combined Modality Therapy. Diagnosis, Differential. Female. Humans. Larynx / pathology. Magnetic Resonance Imaging. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Neoplasms, Second Primary / diagnosis. Neoplasms, Second Primary / pathology. Neoplasms, Second Primary / therapy. Tomography, X-Ray Computed

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[Cites] Laryngorhinootologie. 2001 Aug;80(8):436-8 [11552422.001]

[Cites] Eur J Cancer. 2006 Nov;42(16):2692-705 [16963260.001]

[Cites] An Otorrinolaringol Ibero Am. 2000;27(3):255-63 [11075475.001]

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[Cites] Eur Arch Otorhinolaryngol. 2008 Aug;265(8):979-82 [18038235.001]

[Cites] Clin Radiol. 1976 Jan;27(1):9-15 [177243.001]

[Cites] Clin Breast Cancer. 2008 Apr;8(2):124-33 [18621608.001]

[Cites] Arch Otolaryngol Head Neck Surg. 2000 Feb;126(2):209-14 [10680873.001]

[Cites] Otolaryngol Pol. 1986;40(3):212-6 [3808717.001]

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[Cites] Arch Otolaryngol Head Neck Surg. 1986 Dec;112(12):1269-73 [3768151.001]

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[Cites] Cancer Res. 2008 Jun 15;68(12):4910-8 [18559539.001]

[Cites] N Engl J Med. 2001 Apr 5;344(14):1038-42 [11287973.001]

[Cites] Clin Cancer Res. 2004 Aug 1;10 (15):5215-25 [15297425.001]

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[Cites] J Clin Oncol. 2007 May 1;25(13):1803-5 [17470873.001]

[Cites] J Laryngol Otol. 1987 Jul;101(7):723-5 [3625028.001]

[Cites] Carcinogenesis. 2005 Jun;26(6):1055-63 [15774491.001]

(PMID = 20596682.001).

[ISSN] 1433-0458

[Journal-full-title] HNO

[ISO-abbreviation] HNO

[Language] ger

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Platysma myocutaneous flap for reconstruction of skin defects in the head and neck.

The platysma myocutaneous flap (PMF) is a common reconstructive option for defects in the head and neck region.

[MeSH-major] Head and Neck Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Skin Neoplasms / surgery. Surgical Flaps

[MeSH-minor] Adenocarcinoma / surgery. Aged. Aged, 80 and over. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Cheek / surgery. Ear, External / surgery. Female. Humans. Hyperemia / etiology. Male. Middle Aged. Muscle, Skeletal / blood supply. Muscle, Skeletal / transplantation. Parotid Neoplasms / surgery. Parotid Region / surgery. Retrospective Studies. Skin Transplantation

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[CommentIn] Br J Oral Maxillofac Surg. 2009 Oct;47(7):575 [19628313.001]

(PMID = 18207614.001).

[ISSN] 1532-1940

[Journal-full-title] The British journal of oral & maxillofacial surgery

[ISO-abbreviation] Br J Oral Maxillofac Surg

[Language] eng

[Publication-type] Journal Article

[Publication-country] Scotland

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Novel use of ultrasound-guided surface marking of head and neck tumors invading facial skin.

Malignant tumors of deep head and neck structures can invade skin, but the tumor periphery is difficult to assess clinically.

Ultrasound imaging therefore shows good potential for planning surgical resection with a safe margin and for aiding decisions on donor site and type of flap for reconstruction.

[MeSH-major] Adenocarcinoma / ultrastructure. Carcinoma, Squamous Cell / ultrasonography. Facial Neoplasms / ultrasonography. Head and Neck Neoplasms / pathology. Reconstructive Surgical Procedures / methods

[MeSH-minor] Adult. Cheek. Edema / ultrasonography. Female. Forehead. Humans. Ink. Middle Aged. Mouth Mucosa / pathology. Neoplasm Invasiveness / pathology. Neoplasm Invasiveness / ultrastructure. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / ultrastructure. Neoplasms, Second Primary / pathology. Neoplasms, Second Primary / surgery. Neoplasms, Second Primary / ultrasonography. Patient Care Planning. Skin Neoplasms / pathology. Skin Neoplasms / surgery. Skin Neoplasms / ultrasonography. Surgical Flaps

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(PMID = 16545715.001).

[ISSN] 1528-395X

[Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics

[ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod

[Language] eng

[Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Thallium-201 chloride (Tl-201) accumulation and Na+/K+-ATPase expression in tumours of the head and neck.

OBJECTIVES: The purpose of this report was to evaluate the relationship between the tumour retention index of thallium-201 chloride (Tl-201) scintigraphy and the Na+/K+-ATPase expression in tumours of the head and neck.

METHODS: Tl-201 scintigraphy was performed in 146 patients (129 with malignant tumours, ten with benign tumours and seven with inflammation).

The Na+/K+-ATPase expression was evaluated immunohistochemically in 61 of 129 patients with malignant tumour.

[MeSH-major] Head and Neck Neoplasms / radionuclide imaging. Radiopharmaceuticals. Sodium-Potassium-Exchanging ATPase / analysis. Thallium. Thallium Radioisotopes

[MeSH-minor] Adenocarcinoma / enzymology. Adenocarcinoma / pathology. Adenocarcinoma / radionuclide imaging. Adenolymphoma / enzymology. Adenolymphoma / pathology. Adenolymphoma / radionuclide imaging. Adenoma, Pleomorphic / enzymology. Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / radionuclide imaging. Adult. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / enzymology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / radionuclide imaging. Female. Gene Expression Regulation, Enzymologic. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Male. Middle Aged

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(PMID = 15961594.001).

[ISSN] 0250-832X

[Journal-full-title] Dento maxillo facial radiology

[ISO-abbreviation] Dentomaxillofac Radiol

[Language] eng

[Publication-type] Case Reports; Comparative Study; Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Radiopharmaceuticals; 0 / Thallium Radioisotopes; 7791-12-0 / thallium chloride; AD84R52XLF / Thallium; EC 3.6.3.9 / Sodium-Potassium-Exchanging ATPase

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Recommendations for treatment with IMRT for prostate and head-neck cancer. Axencia de Avaliación de Tecnoloxías Sanitarias de Galicia.

In this article we present the basic standards for the IMRT treatment for prostate and head-neck cancer agreed upon a consensus meeting.

[MeSH-major] Adenocarcinoma / radiotherapy. Head and Neck Neoplasms / radiotherapy. Prostatic Neoplasms / radiotherapy. Radiotherapy, Intensity-Modulated

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[Cites] Radiother Oncol. 2000 Jun;55(3):241-9 [10869739.001]

[Cites] Acta Oncol. 2002;41(6):562-5 [12546530.001]

[Cites] Radiother Oncol. 2001 Dec;61(3):275-80 [11730997.001]

[Cites] Int J Radiat Oncol Biol Phys. 2001 Nov 15;51(4):880-914 [11704310.001]

[Cites] Br J Radiol. 2000 May;73(869):459-69 [10884741.001]

[Cites] Cancer. 2003 Jul 1;98(1):204-11 [12833473.001]

[Cites] Int J Radiat Oncol Biol Phys. 2002 Aug 1;53(5):1111-6 [12128109.001]

[Cites] Int J Radiat Oncol Biol Phys. 2002 Jul 15;53(4):904-12 [12095556.001]

[Cites] Urology. 2001 Jan;57(1):102-7 [11164152.001]

(PMID = 16648101.001).

[ISSN] 1699-048X

[Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

[ISO-abbreviation] Clin Transl Oncol

[Language] eng

[Publication-type] Journal Article; Practice Guideline

[Publication-country] Italy

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Antitumor effects of Nafamostat mesilate on head and neck squamous cell carcinoma.

OBJECTIVE: Nafamostat mesilate (FUT-175), a synthetic serine protease inhibitor, has antitumor activities toward adenocarcinoma, e.g., colon cancer.

We investigated the biological activities of Nafamostat mesilate on cell proliferation, cell-invasive potential and growth factor production in head and neck squamous cell carcinoma (HNSCC).

[MeSH-minor] Cell Line, Tumor. Dose-Response Relationship, Drug. Down-Regulation / drug effects. Female. Gene Expression Regulation, Neoplastic / drug effects. Humans. In Vitro Techniques. Male. Matrix Metalloproteinase 2 / genetics. Matrix Metalloproteinase 9 / genetics. Neoplasm Invasiveness / genetics. RNA, Messenger / genetics. Reverse Transcriptase Polymerase Chain Reaction. Vulvar Neoplasms / pathology

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(PMID = 17337140.001).

[ISSN] 0385-8146

[Journal-full-title] Auris, nasus, larynx

[ISO-abbreviation] Auris Nasus Larynx

[Language] eng

[Publication-type] Journal Article

[Publication-country] Netherlands

[Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Guanidines; 0 / RNA, Messenger; 0 / Transforming Growth Factor beta1; 0 / Vascular Endothelial Growth Factor A; EC 3.4.24.24 / MMP2 protein, human; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9; Y25LQ0H97D / nafamostat

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] The value of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography for staging of primary extranodal head and neck lymphomas.

OBJECTIVES/HYPOTHESIS: Using a retrospective approach, the aim of this study was to confirm the previously described value of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG-PET/CT) in patients with primary extranodal lymphoma of the head and neck region.

METHODS: Twenty-six patients with a primary extranodal head and neck lymphoma (22 diffuse large B-cell lymphoma, one Hodgkin's lymphoma, three malignant T-cell lymphomas) were included.

In one patient, relevant fluorodeoxyglucose (FDG) uptake within the intestine revealed a cecal adenocarcinoma as a secondary primary.

[MeSH-minor] Adenocarcinoma / mortality. Adenocarcinoma / pathology. Adenocarcinoma / radionuclide imaging. Adult. Aged. Aged, 80 and over. Cecal Neoplasms / mortality. Cecal Neoplasms / pathology. Cecal Neoplasms / radionuclide imaging. Female. Fluorodeoxyglucose F18. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Neoplasms, Second Primary / mortality. Neoplasms, Second Primary / pathology. Neoplasms, Second Primary / radionuclide imaging. Radiopharmaceuticals. Retrospective Studies

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(PMID = 20422687.001).

[ISSN] 1531-4995

[Journal-full-title] The Laryngoscope

[ISO-abbreviation] Laryngoscope

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Blood Glucose; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Comparison of animal models for head and neck cancer cachexia.

METHODS: We established two xenograft models in athymic mice and compared these with a cachexigenic cell line, the murine adenocarcinoma 16 (MAC16) cell line.

Eight-week-old female, athymic mice were injected with human head and neck cell lines (JHU022, JHU012) and the MAC16 cell line.

[MeSH-major] Adenocarcinoma / complications. Cachexia / etiology. Head and Neck Neoplasms / complications

[MeSH-minor] Animals. Blotting, Western. Body Composition. Cell Line, Tumor. Cytokines / biosynthesis. Cytokines / blood. Disease Progression. Female. Humans. Mice. Mice, Nude. Neoplasm Proteins / biosynthesis. Neoplasm Transplantation. Neoplasms, Experimental. Transplantation, Heterologous

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(PMID = 17921906.001).

[ISSN] 0023-852X

[Journal-full-title] The Laryngoscope

[ISO-abbreviation] Laryngoscope

[Language] eng

[Grant] United States / NIDDK NIH HHS / DK / DK056350; United States / NCRR NIH HHS / RR / RR00046

[Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Cytokines; 0 / Neoplasm Proteins

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Metallothionein stroma reaction in tumor adjacent healthy tissue in head and neck squamous cell carcinoma and breast adenocarcinoma.

The aim of our study was to evaluate the MT expression in head and neck squamous cells carcinoma and breast adenocarcinoma and their histologically healthy adjacent tissue.

MATERIALS AND METHODS: We have sampled 29 tissue samples in total derived from head and neck cancers and 29 samples of their clear surgical margins, 33 breast adenocarcinomas and 33 clear surgical margins.

RESULTS: MT expression was revealed in 85,7% of head and neck cancers and 94% of breast adenocarcinomas.

MT expression was statistically significantly higher in tumor adjacent tissue than in cancer tissue in cases with the presence of lymph node metastases in both, breast adenocarcinoma and head and neck squamous cell carcinoma.

[MeSH-major] Adenocarcinoma / metabolism. Breast Neoplasms / metabolism. Carcinoma, Squamous Cell / metabolism. Head and Neck Neoplasms / metabolism. Metallothionein / metabolism

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(PMID = 16264399.001).

[ISSN] 0172-780X

[Journal-full-title] Neuro endocrinology letters

[ISO-abbreviation] Neuro Endocrinol. Lett.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Sweden

[Chemical-registry-number] 9038-94-2 / Metallothionein

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Application of an extended collar incision in neck dissection for differentiated thyroid cancer].

OBJECTIVE: To explore a cosmetic incision in the neck dissection for differentiated thyroid carcinoma.

METHODS: An extended collar incision was used for neck dissection in 82 consecutive patients with thyroid carcinoma from May 1999 to December 2006.

Ninety-six procedures of neck dissection were performed in 82 patients, including one radical neck dissection, one type I modified neck dissection, 8 type II modified neck dissections, and 86 type III modified neck dissections.

Eight patients (9.8%) developed complications related to neck dissection.

CONCLUSION: It is feasible to perform a modified neck dissection for differentiated thyroid cancer through the extended collar incision.

[MeSH-major] Adenocarcinoma, Papillary / surgery. Neck Dissection / methods. Thyroid Neoplasms / surgery

[MeSH-minor] Adenocarcinoma, Follicular / pathology. Adenocarcinoma, Follicular / surgery. Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Follow-Up Studies. Humans. Hypocalcemia / etiology. Lymphatic Metastasis. Male. Middle Aged. Young Adult

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(PMID = 19615266.001).

[ISSN] 0253-3766

[Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]

[ISO-abbreviation] Zhonghua Zhong Liu Za Zhi

[Language] chi

[Publication-type] English Abstract; Evaluation Studies; Journal Article

[Publication-country] China

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Investigation of the characters of cervical lymph node metastases of primary malignant tumor beyond head and neck].

OBJECTIVE: To investigate the characters of cervical lymph node metastases of primary tumors beyond head and neck.

METHODS: Among 466 cases of malignant tumor with cervical lymph node metastases treated in Peking Union Medical College Hospital from January 1989 to June 2004, 77 cases of tumor which sites primarily beyond head and neck were studied.

RESULTS: The primary sites of these 77 cases of malignant tumor consisted of lung, stomach, esophagus, galactophore, colon, mediastinum, ovary, uterus, pancreas, liver, mesentery, adrenal gland and rectum.

The proportion of the metastases of malignant tumor from primary site beyond head and neck in each region was 2.1% in LEVEL I, 3.7% in LEVEL III, 14.3% in LEVEL IV, 70.8% in LEVEL V.

Among the cervical lymph node metastases of primary tumor beyond head and neck, 51.9% were low-grade adenocarcinoma, 15.6% were medial-grade adenocarcinoma, 11.7% were low-grade squamous cell carcinoma, 10.4% were medial-grade squamous carcinoma.

CONCLUSIONS: The cervical lymph node metastases of malignant tumor might be seen from many organs beyond head and neck.

The metastases from primary sites beyond head and neck usually focus on LEVEL V (81.8%), especially in the left.

And the primary tumors beyond head and neck metastasis in this region were more than the tumors from head and neck locally.

[MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Neck. Retrospective Studies. Young Adult

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(PMID = 17702413.001).

[ISSN] 1673-0860

[Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

[ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

[Language] chi

[Publication-type] English Abstract; Journal Article

[Publication-country] China

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Does surgical resection of pulmonary metastases of head and neck cancer improve survival?

BACKGROUND: The prognosis of patients with metastasized head and neck cancer is poor.

Limited experience exists with the benefit of resection of lung metastases and systematic mediastinal and hilar lymph node dissection on survival of patients with head and neck carcinoma.

METHODS: Eighty patients undergoing metastasectomy for pulmonary metastases of primary head and neck cancer entered the study.

RESULTS: From 1984 until 2006, pulmonary metastases were diagnosed in 332 patients treated for head and neck cancer; 80 of these were admitted to our department for resection.

Metastases of the primary head and neck tumor were confirmed histologically in 67 patients.

[MeSH-major] Head and Neck Neoplasms / surgery

[MeSH-minor] Adenocarcinoma / mortality. Adenocarcinoma / secondary. Adenocarcinoma / surgery. Adult. Aged. Carcinoma, Squamous Cell / mortality. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Female. Humans. Lung Neoplasms / mortality. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Lymphatic Metastasis. Male. Matched-Pair Analysis. Middle Aged. Neoplasm Staging. Prognosis. Prospective Studies. Retrospective Studies. Survival Rate. Treatment Outcome

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(PMID = 18648883.001).

[ISSN] 1534-4681

[Journal-full-title] Annals of surgical oncology

[ISO-abbreviation] Ann. Surg. Oncol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Comprehensive review of small bowel metastasis from head and neck squamous cell carcinoma.

The majority of these metastatic tumours come from adenocarcinoma primaries; squamous cell carcinoma constitutes a very small proportion of all metastatic small intestinal lesions.

Metastasis to small bowel by head and neck squamous cell carcinoma is extremely rare and carries an unfavourable prognosis.

This work aims at specifying these characteristics by reviewing, compiling, analysing and reporting all published cases in the published literature on small bowel metastasis secondary to head and neck squamous cell carcinoma.

To the best of our knowledge, this is the first comprehensive review article on the small intestinal metastasis from head and neck squamous cell carcinoma.

[MeSH-major] Carcinoma, Squamous Cell / secondary. Head and Neck Neoplasms / pathology. Intestinal Neoplasms / secondary. Intestine, Small / pathology

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[Copyright] Copyright (c) 2010 Elsevier Ltd. All rights reserved.

(PMID = 20189444.001).

[ISSN] 1879-0593

[Journal-full-title] Oral oncology

[ISO-abbreviation] Oral Oncol.

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Multicentric prospective study on the prevalence of sublevel IIb metastases in head and neck cancer.

OBJECTIVE: To evaluate the prevalence of sublevel IIB lymph node (LN) metastases for head and neck primary tumors in a large cohort of patients.

PATIENTS: Between 2003 and 2005, 297 patients (male to female ratio, 3.5:1; mean age, 58.8 years [range, 18-89 years]) affected by head and neck cancer were treated by surgery on the primary tumor and/or the neck.

Primary site distribution included the following: oral cavity in 111 patients, larynx in 92, oropharynx in 32, thyroid gland in 22, skin of the lateral face or scalp in 16, hypopharynx in 11, unknown primary in 7, and parotid gland in 6.

INTERVENTIONS: All patients underwent unilateral or bilateral neck dissection (ND) with therapeutic or elective intent according to the primary site and clinical T (cT) and clinical N (cN) status.

The influence of several factors (institution in which the surgical procedure was performed, sex of the patient, site of primary, histotype, pathologic T [pT] status, cN status, lower level involved in the neck together with sublevel IIB, association with sublevel IIA metastasis, ipsilateral number of involved levels, and previous surgical treatment limited on the primary site) on the prevalence of sublevel IIB metastasis was statistically evaluated by the Pearson chi(2) test or Fisher exact test.

The overall prevalence of sublevel IIB metastases was 5.6% (26 neck sides).

Tumor histologic type in the sublevel IIB+ population was squamous cell carcinoma in 80%, papillary carcinoma in 8%, melanoma in 8%, and adenocarcinoma in 4%.

[MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Papillary / epidemiology. Carcinoma, Papillary / pathology. Carcinoma, Papillary / surgery. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Cross-Sectional Studies. Female. Humans. Lymph Node Excision. Male. Melanoma / epidemiology. Melanoma / pathology. Melanoma / surgery. Middle Aged. Neoplasm Staging. Prognosis. Prospective Studies. Skin Neoplasms / epidemiology. Skin Neoplasms / pathology. Skin Neoplasms / surgery

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(PMID = 17875856.001).

[ISSN] 0886-4470

[Journal-full-title] Archives of otolaryngology--head & neck surgery

[ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.

[Language] eng

[Publication-type] Journal Article; Multicenter Study

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Neck masses secondary to heterotopic salivary gland tissue: a 25-year experience.

METHODS: A retrospective chart review revealed 24 patients with asymptomatic neck masses treated between 1976 and 2001, whose pathology demonstrated heterotopic salivary tissue or neoplasms arising from heterotopic salivary tissue.

Malignant tumors included mucoepidermoid (3), acinic cell (2), and adenocarcinoma (1).

Patients were treated by a superficial parotidectomy, neck dissection, or simple excision depending on site and preoperative workup.

Tumorigenic changes arise from heterotopic nodal inclusions, and although infrequent, should be considered in the differential diagnosis for isolated neck/periparotid masses and parotid Warthin's tumor.

Suggested management, after a thorough clinical exam/needle aspiration biopsy, includes an imaging survey of the parotid gland and neck lymphatics with an appropriate resection to include a simple excision, parotidectomy, neck dissection, and/or irradiation as indicated.

Isolated low-grade malignant lesions/benign lesions are adequately managed by excision or parotidectomy alone.

High-grade malignant lesions require more extended surgery with possible irradiation.

[MeSH-major] Adenocarcinoma / pathology. Adenoma, Pleomorphic / pathology. Choristoma / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands

[MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy, Needle. Follow-Up Studies. Humans. Lymph Nodes. Middle Aged. Neck. Retrospective Studies

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(PMID = 15742261.001).

[ISSN] 0196-0709

[Journal-full-title] American journal of otolaryngology

[ISO-abbreviation] Am J Otolaryngol

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Feasibility of flap reconstruction in conjunction with intraoperative radiation therapy for advanced and recurrent head and neck cancer.

We review our experience with IORT in patients undergoing resection of head and neck cancer and flap reconstruction.

METHODS: A retrospective chart review was performed on all patients at Beth Israel Medical Center who underwent IORT for head and neck cancer between 2000 and 2007.

RESULTS: All patients had complex surgical wounds of the face, upper aerodigestive tract, or neck who received IORT in conjunction with pedicled or free flap closure.

[MeSH-major] Head and Neck Neoplasms / radiotherapy. Intraoperative Care. Neoplasm Recurrence, Local / radiotherapy. Radiology, Interventional. Reconstructive Surgical Procedures / methods. Surgical Flaps

[MeSH-minor] Adenocarcinoma / radiotherapy. Adenocarcinoma / surgery. Adolescent. Adult. Aged. Carcinoma, Squamous Cell / radiotherapy. Carcinoma, Squamous Cell / surgery. Feasibility Studies. Female. Follow-Up Studies. Humans. Male. Middle Aged. Postoperative Complications. Radiotherapy Dosage. Reoperation. Retrospective Studies. Surgical Wound Dehiscence / etiology. Treatment Outcome. Wound Healing / physiology

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(PMID = 18165718.001).

[ISSN] 0023-852X

[Journal-full-title] The Laryngoscope

[ISO-abbreviation] Laryngoscope

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] The reasons for discrepancies in target volume delineation : a SASRO study on head-and-neck and prostate cancers.

MATERIAL AND METHODS: 18 Swiss radiooncology centers were invited to delineate volumes for one prostate and one head-and-neck case.

Correlation between drawn and stated margins was fair in the prostate case and poor in the head-and-neck case.

[MeSH-major] Adenocarcinoma / radiotherapy. Carcinoma, Squamous Cell / radiotherapy. Head and Neck Neoplasms / radiotherapy. Prostatic Neoplasms / radiotherapy. Radiotherapy Planning, Computer-Assisted. Tongue Neoplasms / radiotherapy

[MeSH-minor] Aged. CD-ROM. Humans. Lymph Nodes / pathology. Male. Neoplasm Staging. Observer Variation. Prostate / pathology. Prostate-Specific Antigen / blood. Surveys and Questionnaires. Tomography, X-Ray Computed. Tongue / pathology

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(PMID = 16896591.001).

[ISSN] 0179-7158

[Journal-full-title] Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]

[ISO-abbreviation] Strahlenther Onkol

[Language] eng

[Publication-type] Case Reports; Comparative Study; Journal Article

[Publication-country] Germany

[Chemical-registry-number] EC 3.4.21.77 / Prostate-Specific Antigen

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Results of a surgical resection of pulmonary metastasis from malignant head and neck tumor.

There have been only a few reports about a surgical resection of pulmonary metastasis from malignant head and neck tumor.

We retrospectively reviewed 25 patients who underwent a pulmonary metastasectomy from malignant head and neck tumor at Kyushu University Hospital from 1981 through 2008.

To obtain a long survival, a positive surgical resection is considered to be an effective and standard treatment for pulmonary metastasis from malignant head and neck tumor.

It is also necessary, however, to elucidate fully the primary site and histology of such pulmonary metastasis.

[MeSH-major] Head and Neck Neoplasms / pathology. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Lymph Node Excision / methods. Lymph Nodes / pathology. Neoplasm Recurrence, Local / mortality

[MeSH-minor] Adenocarcinoma / mortality. Adenocarcinoma / secondary. Adenocarcinoma / surgery. Adolescent. Adult. Aged. Carcinoma, Squamous Cell / mortality. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Disease-Free Survival. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Pneumonectomy / methods. Pneumonectomy / mortality. Proportional Hazards Models. Retrospective Studies. Risk Assessment. Survival Analysis. Young Adult

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[Copyright] 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.

(PMID = 20123888.001).

[ISSN] 1569-9285

[Journal-full-title] Interactive cardiovascular and thoracic surgery

[ISO-abbreviation] Interact Cardiovasc Thorac Surg

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Expression of laminin 5 basement membrane components in invading and recurring adenoid cystic carcinoma of the head and neck.

OBJECTIVE: Adenoid cystic carcinoma (ACC) of the head and neck grows slowly with structural differentiation, however, this tumor nevertheless also shows a highly invasive potential and a high recurrence rate.

The laminin 5 BM matrices might play an important role not only in the differentiation and growth, but also in the invasion and recurrence of ACC of the head and neck.

[MeSH-major] Carcinoma, Adenoid Cystic / genetics. Carcinoma, Adenoid Cystic / metabolism. Head and Neck Neoplasms / genetics. Head and Neck Neoplasms / metabolism. Laminin / genetics. Laminin / metabolism

[MeSH-minor] Adenocarcinoma / genetics. Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adult. Aged. Antibodies, Monoclonal / metabolism. Basement Membrane / metabolism. Basement Membrane / pathology. Collagen Type IV / metabolism. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local

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(PMID = 16332421.001).

[ISSN] 0385-8146

[Journal-full-title] Auris, nasus, larynx

[ISO-abbreviation] Auris Nasus Larynx

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Netherlands

[Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Collagen Type IV; 0 / LAMC2 protein, human; 0 / Laminin

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] High-dose-rate interstitial brachytherapy in recurrent and previously irradiated head and neck cancers--preliminary results.

PURPOSE: Although high-dose-rate brachytherapy (HDRBT) offers significant advantages over low dose rate brachytherapy, there are scant data on improved local control (LC) and treatment-related complications in patients with recurrent head and neck (H&N) cancers.

The treatment sites were oral cavity/oropharynx (11/30), neck (10/30), face/nasal cavity (6/30), and parotid bed (3/30).

[MeSH-major] Brachytherapy. Head and Neck Neoplasms / radiotherapy. Hemibody Irradiation. Neoplasm Recurrence, Local

[MeSH-minor] Adenocarcinoma / radiotherapy. Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / radiotherapy. Carcinoma, Squamous Cell / radiotherapy. Female. Follow-Up Studies. Humans. Male. Melanoma / radiotherapy. Middle Aged. Radiation Injuries / etiology. Radiotherapy Dosage. Retrospective Studies. Sarcoma / radiotherapy. Survival Analysis. Time Factors. Treatment Outcome. Tumor Burden / radiation effects

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(PMID = 17434110.001).

[ISSN] 1538-4721

[Journal-full-title] Brachytherapy

[ISO-abbreviation] Brachytherapy

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Distinguishing pseudoepitheliomatous hyperplasia from squamous cell carcinoma in mucosal biopsy specimens from the head and neck.

CONTEXT: The differentiation of pseudoepitheliomatous hyperplasia from invasive squamous cell carcinoma is a difficult and frequently encountered distinction, especially in biopsy specimens from head and neck mucosa.

OBJECTIVE: To distinguish pseudoepitheliomatous hyperplasia from invasive squamous cell carcinoma, utilizing a panel of antibodies to various epithelial and stromal elements (p53, matrix metalloproteinase 1, E-cadherin, and collagen IV) that has been shown to be useful in differentiating intestinal adenomas with invasive adenocarcinoma from displaced adenomatous epithelium.

DESIGN: Thirty-three archival specimens (16 squamous cell carcinoma [12 with invasion and 4 with microinvasion] and 17 pseudoepitheliomatous hyperplasia) from head and neck mucosal locations were immunostained and examined by the authors.

It appeared fragmented in benign inflamed and malignant areas and therefore was not useful.

[MeSH-major] Carcinoma, Squamous Cell / diagnosis. Granular Cell Tumor / diagnosis. Head and Neck Neoplasms / diagnosis. Mouth Mucosa / pathology. Skin Diseases / diagnosis

[MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Biopsy. Cadherins / metabolism. Child. Diagnosis, Differential. Female. Humans. Hyperplasia / pathology. Immunoenzyme Techniques. Male. Matrix Metalloproteinase 1 / metabolism. Middle Aged. Tumor Suppressor Protein p53 / metabolism

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[CommentIn] Arch Pathol Lab Med. 2006 Jun;130(6):764; author reply 764 [16740023.001]

(PMID = 16048394.001).

[ISSN] 1543-2165

[Journal-full-title] Archives of pathology & laboratory medicine

[ISO-abbreviation] Arch. Pathol. Lab. Med.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cadherins; 0 / Tumor Suppressor Protein p53; EC 3.4.24.7 / Matrix Metalloproteinase 1

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Lymphocyte-depleted thymic remnants: a potential diagnostic pitfall in the evaluation of central neck dissections.

The head and neck region is a frequent site for potentially confusing incidental benign findings not related to the primary pathologic process and having no impact on patient prognosis.

We report 3 cases of lymphocyte-poor thymic remnants identified in central cervical (level VI) lymph node dissections for unrelated benign and malignant pathology.

[MeSH-major] Incidental Findings. Neck Dissection. Thymus Gland / pathology

[MeSH-minor] Adenocarcinoma, Papillary / surgery. Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Head and Neck Neoplasms / pathology. Humans. Hyperparathyroidism / surgery. Immunohistochemistry. Lymphocytes / pathology. Male. Parathyroidectomy. Thyroid Neoplasms / surgery

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(PMID = 19846811.001).

[ISSN] 1943-7722

[Journal-full-title] American journal of clinical pathology

[ISO-abbreviation] Am. J. Clin. Pathol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Polymorphous low-grade adenocarcinoma of the head and neck.

PURPOSE OF REVIEW: Polymorphous low-grade adenocarcinoma is an entity described in 1984.

The natural history of polymorphous low-grade adenocarcinoma is distinct from other malignant salivary tumours.

RECENT FINDINGS: Polymorphous low-grade adenocarcinoma is a slow-growing tumour that is locally invasive.

Diagnosis is established after a biopsy because cytological studies are not helpful.

The role of radiation therapy is not clear in the management of polymorphous low-grade adenocarcinoma.

SUMMARY: Polymorphous low-grade adenocarcinoma is primarily a pathologic diagnosis.

[MeSH-major] Adenocarcinoma / pathology. Salivary Gland Neoplasms / pathology

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(PMID = 18327037.001).

[ISSN] 1531-6998

[Journal-full-title] Current opinion in otolaryngology & head and neck surgery

[ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] United States

[Number-of-references] 60

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Carbon ion radiotherapy for basal cell adenocarcinoma of the head and neck: preliminary report of six cases and review of the literature.

BACKGROUND: Basal cell adenocarcinoma accounts for approximately 1.6% of all salivary gland neoplasms.

METHODS: Case records of 6 patients with diagnosis of basal cell adenocarcinoma of the head and neck, who were treated by carbon ion radiotherapy with 64.0 GyE/16 fractions in our institution, were retrospectively reviewed.

CONCLUSIONS: Carbon ion radiotherapy should be considered as an appropriate curative approach for treatment of basal cell adenocarcinoma in certain cases, particularly in cases of unresectable disease and postoperative gross residual or recurrent disease.

[MeSH-major] Adenocarcinoma / radiotherapy. Carbon / therapeutic use. Head and Neck Neoplasms / radiotherapy. Heavy Ions / therapeutic use

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[Cites] Int J Radiat Oncol Biol Phys. 2000 Oct 1;48(3):737-43 [11020570.001]

[Cites] Histopathology. 2003 Jun;42(6):610-4 [12786899.001]

[Cites] Arch Otolaryngol. 1978 Feb;104(2):111-6 [629699.001]

[Cites] Oral Surg Oral Med Oral Pathol. 1990 Apr;69(4):461-9 [2326038.001]

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[Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jan;103(1):77-84 [17178498.001]

(PMID = 20920325.001).

[ISSN] 1748-717X

[Journal-full-title] Radiation oncology (London, England)

[ISO-abbreviation] Radiat Oncol

[Language] eng

[Publication-type] Case Reports; Journal Article; Review

[Publication-country] England

[Chemical-registry-number] 7440-44-0 / Carbon

[Other-IDs] NLM/ PMC2958970

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Short-term efficacy of cetuximab combined with radiotherapy or chemotherapy on head and neck cancer: a report of 11 cases].

BACKGROUND AND OBJECTIVE: Cetuximab combined with radiotherapy or chemotherapy has been used to treat head and neck cancer in recent years, but few reports are available in China now.

This study was to summarize our experiences in treating patients with head and neck cancer cetuximab.

METHODS: From October 1st, 2005 to September 30th, 2008, six with patients head and neck cancer were treated using cetuximab combined with radiotherapy and five were treated using cetuximab combined with chemotherapy in Sun Yat-sen University Cancer Center.

CONCLUSION: Cetuximab combined with either radiotherapy or chemotherapy are good options for suitable patients with head and neck cancer.

[MeSH-major] Antibodies, Monoclonal / therapeutic use. Carcinoma, Squamous Cell / drug therapy. Head and Neck Neoplasms / drug therapy. Hypopharyngeal Neoplasms / drug therapy

[MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / radiotherapy. Adult. Aged. Aged, 80 and over. Antibodies, Monoclonal, Humanized. Antineoplastic Agents / therapeutic use. Cetuximab. Combined Modality Therapy. Disease Progression. Exanthema / chemically induced. Female. Follow-Up Studies. Humans. Male. Middle Aged. Remission Induction. Retrospective Studies

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(PMID = 19728918.001).

[Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer

[ISO-abbreviation] Ai Zheng

[Language] chi

[Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] China

[Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents; PQX0D8J21J / Cetuximab

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Scintigraphy for interpretation of malignant tumours of the head and neck: comparison of technetium-99m-hexakis-2-methoxyisobutylisonitrile (Tc-MIBI) and thallium-201-chloride (Tl-201).

METHODS: Dynamic and static scintigraphic imaging with 99Tc(m)-MIBI and Tl-201 were performed on patients with a variety of malignant and benign tumours.

In addition to these factors, the grade of tissue differentiation and tumour size were evaluated to clarify the difference between 99Tc(m)-MIBI and Tl-201 for the diagnosis of malignant tumours of the head and neck.

CONCLUSIONS: There was no major difference between 99Tc(m)-MIBI and Tl-201scintigraphy with respect to accuracy of diagnosis of malignant tumours of the head and neck.

[MeSH-major] Carcinoma, Squamous Cell / radionuclide imaging. Head and Neck Neoplasms / radionuclide imaging. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Thallium Radioisotopes

[MeSH-minor] Adenocarcinoma / radionuclide imaging. Adenolymphoma / radionuclide imaging. Adenoma, Pleomorphic / radionuclide imaging. Adult. Aged. Aged, 80 and over. Cell Differentiation. Female. Humans. Male. Middle Aged. Regional Blood Flow / physiology. Retrospective Studies. Thallium. Time Factors

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(PMID = 16120875.001).

[ISSN] 0250-832X

[Journal-full-title] Dento maxillo facial radiology

[ISO-abbreviation] Dentomaxillofac Radiol

[Language] eng

[Publication-type] Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / Radiopharmaceuticals; 0 / Thallium Radioisotopes; 7791-12-0 / thallium chloride; 971Z4W1S09 / Technetium Tc 99m Sestamibi; AD84R52XLF / Thallium

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] A study on the prognostic evaluation of carbon ion radiotherapy for head and neck adenocarcinoma with C-11 methionine PET.

PURPOSE: Carbon ion radiotherapy (CIRT) has been developed, and a phase I/II CIRT trial has been conducted in patients with adenocarcinoma in the head and neck region.

We evaluated whether the L-methyl [11C]-methionine (MET) uptake could be an early predictor for local recurrence, metastasis, and the prognosis in patients with adenocarcinoma in the head and neck region.

CONCLUSIONS: The determination of treatment effectiveness using TNR in CIRT for head and neck adenocarcinoma is an independent factor for predicting local recurrence, the incidence of metastasis, and the prognosis.

MET-PET is therefore considered to be useful for determining the treatment effectiveness in patients with head and neck adenocarcinoma undergoing CIRT.

[MeSH-major] Adenocarcinoma / radiotherapy. Head and Neck Neoplasms / radiotherapy. Methionine. Positron-Emission Tomography

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(PMID = 20369300.001).

[ISSN] 1860-2002

[Journal-full-title] Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

[ISO-abbreviation] Mol Imaging Biol

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Carbon Radioisotopes; AE28F7PNPL / Methionine

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Endoscopic hemithyroidectomy with prophylactic ipsilateral central neck dissection via an unilateral axillo-breast approach without gas insufflation for unilateral micropapillary thyroid carcinoma: preliminary report.

However, few specific data exist on endoscopic thyroidectomy with central neck dissection (CND) for micropapillary thyroid carcinoma.

[MeSH-major] Adenocarcinoma, Papillary / surgery. Endoscopy / methods. Lymph Node Excision / methods. Thyroid Neoplasms / surgery. Thyroidectomy / methods

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(PMID = 19688395.001).

[ISSN] 1432-2218

[Journal-full-title] Surgical endoscopy

[ISO-abbreviation] Surg Endosc

[Language] eng

[Publication-type] Comparative Study; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Head and neck cancer in South East England between 1995-1999 and 2000-2004: An estimation of incidence and distribution by site, stage and histological type.

Population-based data on head and neck cancer (HNC) stage and histological type are poorly described for England; these data are essential for clinical management and research.

Males were two to six times as likely as females to be diagnosed with HNC and there was a trend toward younger age at diagnosis over time.

[MeSH-major] Head and Neck Neoplasms / epidemiology

[MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Adolescent. Adult. Age Distribution. Aged. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. Child. Child, Preschool. England / epidemiology. Female. Humans. Incidence. Infant. Infant, Newborn. Male. Middle Aged. Registries. Sex Distribution. Young Adult

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(PMID = 19251472.001).

[ISSN] 1879-0593

[Journal-full-title] Oral oncology

[ISO-abbreviation] Oral Oncol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Fine needle aspiration cytology in the diagnosis of head and neck masses: accuracy and diagnostic problems.

PURPOSE: Fine needle aspiration (FNA) cytology is an established technique associated with minimal complications compared with more invasive techniques such as wide core needle biopsy or open biopsy, and as such, very suitable for obtaining material in the delicate region of head and neck (H&N).

Sixty-four (12.6%) FNA specimens were inadequate for diagnosis.

The overall accuracy rate of FNA cytology, whether malignant or benign, was 91.89%, while the diagnostic accuracy for the exact type of tumor was 87.16%.

The sensitivity and specificity of FNA cytology in determining a malignant diagnosis were 91.5% and 92.85%, respectively.

[MeSH-major] Head and Neck Neoplasms / diagnosis. Lymphoma / diagnosis. Pseudolymphoma / diagnosis

[MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / secondary. Biopsy, Fine-Needle. Biopsy, Needle. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / secondary. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / secondary. Cytological Techniques. Diagnosis, Differential. Diagnostic Errors. Humans. Neoplasm Staging. Prognosis. Sensitivity and Specificity

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(PMID = 20148458.001).

[ISSN] 1107-0625

[Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology

[ISO-abbreviation] J BUON

[Language] eng

[Publication-type] Journal Article

[Publication-country] Greece

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes.

MATERIALS AND METHODS: The study population consisted of 88 intensity-modulated radiation therapy (IMRT)-treated head-and-neck cancer patients.

[MeSH-major] DNA Repair / genetics. Deglutition Disorders / genetics. Head and Neck Neoplasms / radiotherapy. Polymorphism, Genetic / genetics. Radiotherapy, Intensity-Modulated / adverse effects

[MeSH-minor] Adenocarcinoma / genetics. Adenocarcinoma / radiotherapy. Adult. Aged. Aged, 80 and over. Antigens, Nuclear / genetics. Arabidopsis Proteins / genetics. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / radiotherapy. DNA Ligases / genetics. DNA-Binding Proteins / genetics. Female. Humans. Male. Middle Aged. Mouth / radiation effects. Mouth Mucosa / radiation effects. Pharyngeal Muscles / radiation effects. Rad51 Recombinase / genetics. Radiodermatitis / genetics. Radiotherapy Dosage. Regression Analysis

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(PMID = 19251090.001).

[ISSN] 1879-355X

[Journal-full-title] International journal of radiation oncology, biology, physics

[ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Antigens, Nuclear; 0 / Arabidopsis Proteins; 0 / DNA-Binding Proteins; 0 / Ku autoantigen; 0 / X-ray repair cross complementing protein 3; EC 2.7.7.- / ATRAD51 protein, Arabidopsis; EC 2.7.7.- / Rad51 Recombinase; EC 6.5.1.- / DNA Ligases; EC 6.5.1.1 / DNA ligase (ATP)

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Oral malignant melanomas and other head and neck neoplasms in Danish dogs--data from the Danish Veterinary Cancer Registry.

BACKGROUND: Head and neck cancers (HNC) are relatively common and often very serious diseases in both dogs and humans.

Neoplasms originating in the head and neck region are a heterogeneous group.

In humans oral malignant melanoma (OMM) is extremely rare, but represents a particular challenge since it is highly aggressive as is the canine counterpart, which thus may be of interest as a spontaneous animal model.

Also the proportions of benign and malignant neoplasms of different locations in dogs were compared using Fisher's exact test.

RESULTS: A total of 1768 cases of neoplasias (679 malignant, 826 benign, 263 unknown) were submitted.

Of these, 64 (50%) were malignant and 44 (34%) benign.

The most common types of malignant neoplasia were SCC (18; 28% of malignant), OMM (13; 20% of malignant), soft tissue sarcoma (11; 17% of malignant) and adenocarcinoma (5; 11% of malignant).

CONCLUSIONS: In the current study, the proportion of neoplasia in the head and neck region in dogs in Denmark was similar to other canine studies and significantly more common than in humans with a large proportion of malignancies.

[MeSH-major] Dog Diseases / epidemiology. Head and Neck Neoplasms / veterinary. Melanoma / veterinary. Mouth Neoplasms / veterinary. Registries

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(PMID = 20021647.001).

[ISSN] 1751-0147

[Journal-full-title] Acta veterinaria Scandinavica

[ISO-abbreviation] Acta Vet. Scand.

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Other-IDs] NLM/ PMC2803174

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Should we treat lung metastases from adenoid cystic carcinoma of the head and neck in asymptomatic patients?

Adenoid cystic carcinoma is a rare malignant tumor that is well known for its deceptively encouraging 5-year survival rate and its dismal survival rate at longer intervals.

[MeSH-major] Carcinoma, Adenoid Cystic / secondary. Head and Neck Neoplasms / pathology. Lung Neoplasms / secondary

[MeSH-minor] Adenocarcinoma / secondary. Adenocarcinoma / surgery. Adult. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Female. Humans. Prognosis. Thoracotomy. Tomography, X-Ray Computed. Treatment Outcome

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(PMID = 19517404.001).

[ISSN] 1942-7522

[Journal-full-title] Ear, nose, & throat journal

[ISO-abbreviation] Ear Nose Throat J

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Primary lung cancer after treatment of head and neck cancer without lymph node metastasis: is there a role for autofluorescence bronchoscopy?

BACKGROUND: Head and neck cancer (HNC) is the 5th most common cancer worldwide.

[MeSH-major] Bronchoscopy. Carcinoma, Non-Small-Cell Lung / diagnosis. Head and Neck Neoplasms / pathology. Neoplasms, Second Primary / diagnosis

[MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / drug therapy. Adenocarcinoma, Bronchiolo-Alveolar / diagnosis. Adenocarcinoma, Bronchiolo-Alveolar / drug therapy. Adult. Aged. Carcinoma, Large Cell / diagnosis. Carcinoma, Large Cell / drug therapy. Female. Fluorescence. Humans. Lung Neoplasms / diagnosis. Lung Neoplasms / drug therapy. Lymphatic Metastasis. Male. Middle Aged. Prognosis. Prospective Studies. Small Cell Lung Carcinoma / diagnosis. Small Cell Lung Carcinoma / drug therapy. Smoking. Survival Rate. Treatment Outcome

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[CommentIn] Lung Cancer. 2009 Aug;65(2):255 [19410330.001]

(PMID = 18486989.001).

[ISSN] 0169-5002

[Journal-full-title] Lung cancer (Amsterdam, Netherlands)

[ISO-abbreviation] Lung Cancer

[Language] eng

[Publication-type] Journal Article

[Publication-country] Ireland

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Screening for distant metastases in patients with head and neck cancer: is there a role for (18)FDG-PET?

In addition, (18)FDG-PET detected second primary tumours in two patients (hepatocellular carcinoma and abdominal adenocarcinoma).

[MeSH-major] Carcinoma, Squamous Cell / radionuclide imaging. Carcinoma, Squamous Cell / secondary. Fluorodeoxyglucose F18. Head and Neck Neoplasms / radionuclide imaging. Positron-Emission Tomography / methods. Radiopharmaceuticals

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(PMID = 16266820.001).

[ISSN] 1368-8375

[Journal-full-title] Oral oncology

[ISO-abbreviation] Oral Oncol.

[Language] eng

[Publication-type] Evaluation Studies; Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] A new combined approach to the nasopharynx in head and neck plastic surgery: technique and application.

[MeSH-major] Adenocarcinoma / surgery. Nasopharyngeal Neoplasms / surgery. Nasopharynx / surgery

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(PMID = 16834806.001).

[ISSN] 1748-5460

[Journal-full-title] The Journal of laryngology and otology

[ISO-abbreviation] J Laryngol Otol

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Clearing up clear cell tumours of the head and neck: differentiation of hyalinizing and odontogenic varieties.

[MeSH-major] Adenocarcinoma, Clear Cell / diagnosis. Head and Neck Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

[MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged. Tomography, X-Ray Computed

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(PMID = 20828504.001).

[ISSN] 1916-0216

[Journal-full-title] Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

[ISO-abbreviation] J Otolaryngol Head Neck Surg

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Canada

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Use of the anterolateral thigh flap and combined vascularised fascia lata sling to provide static support following facial nerve resection in head and neck cancer reconstruction.

[MeSH-minor] Adenocarcinoma / surgery. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / surgery. Facial Paralysis / prevention & control. Female. Head and Neck Neoplasms / surgery. Humans. Male. Melanoma / surgery. Middle Aged. Thigh

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(PMID = 18639506.001).

[ISSN] 1878-0539

[Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS

[ISO-abbreviation] J Plast Reconstr Aesthet Surg

[Language] eng

[Publication-type] Case Reports; Letter

[Publication-country] Netherlands

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Salivary gland cystadenocarcinoma of the mobile tongue, low-grade papillary adenocarcinoma variant: a case report.

Cystadenocarcinoma is a rare malignant neoplasm of the salivary gland.

Treatment involves local excision; neck dissection and postoperative radiation therapy are used for clinically positive neck metastases.

[MeSH-major] Cystadenocarcinoma, Papillary / diagnosis. Salivary Gland Neoplasms / diagnosis

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(PMID = 17240709.001).

[ISSN] 0145-5613

[Journal-full-title] Ear, nose, & throat journal

[ISO-abbreviation] Ear Nose Throat J

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States