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1. Lozano M, Gonzalez F: [Adenocarcinoma with apocrine differentiation of the lacrimal gland]. Arch Soc Esp Oftalmol; 2007 Apr;82(4):229-31
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  • [Title] [Adenocarcinoma with apocrine differentiation of the lacrimal gland].
  • [Transliterated title] Adenocarcinoma con diferenciación apocrina de la glándula lagrimal.
  • The histopathologic study showed a tumor consistent with an adenocarcinoma of the lacrimal gland with apocrine differentiation.
  • [MeSH-major] Adenocarcinoma / pathology. Eye Diseases / pathology. Lacrimal Apparatus Diseases / pathology
  • [MeSH-minor] Aged. Apocrine Glands / pathology. Blepharoptosis / etiology. Cell Differentiation. Diagnosis, Differential. Fatal Outcome. Humans. Incidental Findings. Male. Recurrence. Stroke / complications. Stroke / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 17443428.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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2. Barbón JJ, González-Tuero J, Gay LL, Pérez-García FJ, Sampedro A: [Regression of a choroidal metastasis from prostate adenocarcinoma after hormonal therapy]. Arch Soc Esp Oftalmol; 2007 Nov;82(11):715-7
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  • [Title] [Regression of a choroidal metastasis from prostate adenocarcinoma after hormonal therapy].
  • [Transliterated title] Regresión de una metástasis coroidea de adenocarcinoma de próstata con tratamiento hormonal.
  • CASE REPORT: We report a case of a patient diagnosed with prostatic adenocarcinoma with multiple bone metastases and a choroidal metastasis in his left eye.
  • DISCUSSION: Complete resolution of choroidal metastases of prostatic adenocarcinoma with hormonal therapy is exceptional, but the effect of this treatment on such metastases should be observed before recommending radiation therapy.
  • [MeSH-major] Adenocarcinoma / drug therapy. Adenocarcinoma / secondary. Androgen Antagonists / therapeutic use. Anilides / therapeutic use. Antineoplastic Agents, Hormonal / therapeutic use. Choroid Neoplasms / secondary. Nitriles / therapeutic use. Prostatic Neoplasms / drug therapy. Tosyl Compounds / therapeutic use

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  • (PMID = 17979041.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Androgen Antagonists; 0 / Anilides; 0 / Antineoplastic Agents, Hormonal; 0 / Nitriles; 0 / Tosyl Compounds; A0Z3NAU9DP / bicalutamide; EC 3.4.21.77 / Prostate-Specific Antigen
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3. Melo DH, Pierre Filho Pde T, Gomes PR, Holanda AG, Amadei LP: [Choroidal metastasis of gastric adenocarcinoma as a first sign of systemic disease recurrence: case report]. Arq Bras Oftalmol; 2010 Sep-Oct;73(5):467-8
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  • [Title] [Choroidal metastasis of gastric adenocarcinoma as a first sign of systemic disease recurrence: case report].
  • [Transliterated title] Metástase de adenocarcinoma gástrico para a coróide como um primeiro sinal de recorrência de doença sistêmica: relato de caso.
  • To describe a patient with unilateral metastatic choroidal gastric adenocarcinoma as a first sign of systemic dissemination.
  • A 54-year-old woman presented with a 7-month history of progressive pain and decrease in vision in her left eye.
  • She had undergone total gastrectomy due to gastric adenocarcinoma two years previously.
  • Examination of the left eye revealed an elevated creamy yellow choroidal tumor infiltrating the macular area and extending around the optic nerve head, suggesting metastasis.
  • Treatment was enucleation of the affected eye.
  • This patient represents a rare occurrence of metastatic gastric adenocarcinoma to the choroid, developing as a first sign of systemic recurrence.
  • [MeSH-major] Adenocarcinoma / secondary. Choroid Neoplasms / secondary. Orbital Neoplasms / secondary. Stomach Neoplasms / pathology

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  • (PMID = 21225136.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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4. Chekrine T, Tawfiq N, Bouchbika Z, Benchakroun N, Jouhadi H, Sahraoui S, Benider A: [Ocular metastasis heralding gastric adenocarcinoma]. Rev Med Interne; 2010 Oct;31(10):e14-6
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  • [Title] [Ocular metastasis heralding gastric adenocarcinoma].
  • Ocular metastasis is a rare presenting feature of gastric adenocarcinoma.
  • We report a 48-year-old woman who presented with a decrease in visual acuity of the right eye leading to the discovery of an ocular metastasis.
  • Diagnostic work-up identified a gastric adenocarcinoma with pulmonary metastases.
  • The patient died 6 months after the diagnosis of respiratory failure.

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  • [Copyright] Copyright © 2010 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.
  • (PMID = 20554090.001).
  • [ISSN] 1768-3122
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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5. Resto VA, Krane JF, Faquin WC, Lin DT: Immunohistochemical distinction of intestinal-type sinonasal adenocarcinoma from metastatic adenocarcinoma of intestinal origin. Ann Otol Rhinol Laryngol; 2006 Jan;115(1):59-64
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  • [Title] Immunohistochemical distinction of intestinal-type sinonasal adenocarcinoma from metastatic adenocarcinoma of intestinal origin.
  • OBJECTIVES: Distinction of intestinal-type sinonasal adenocarcinoma (ITAC) from adenocarcinoma of intestinal origin metastatic to the sinonasal cavity may be extremely difficult on histologic grounds alone.
  • We studied the role of cytokeratin (CK) and mucin (MUC) expression in differentiating ITAC, metastatic adenocarcinoma of intestinal origin, and non-intestinal-type sinonasal adenocarcinoma (non-ITAC).
  • METHODS: We stained specimens from 5 cases of ITAC and 4 cases of non-ITAC, along with 4 colonic and 3 duodenal adenocarcinoma controls, with CK7 and CK20, MUC2 and MUC5, neuron-specific enolase (NSE), chromogranin (CHR), and carcinoembryonic antigen (CEA) in order to examine the possible combinations of markers that best aid in the diagnosis of these lesions.
  • [MeSH-major] Adenocarcinoma / metabolism. Colonic Neoplasms / metabolism. Duodenal Neoplasms / metabolism. Keratins / metabolism. Mucins / metabolism. Paranasal Sinus Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Keratin-20. Keratin-7. Male. Middle Aged. Mucin-2. Retrospective Studies

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  • (PMID = 16466101.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 0 / MUC2 protein, human; 0 / Mucin-2; 0 / Mucins; 68238-35-7 / Keratins
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6. Llarena Ibarguren R, García-Olaverri Rodríguez J, Villafruela Mateos A, Azurmendi Arin I, Olano Grasa I, Pertusa Peña C: [Metastases in the paranasal sinuses secondary to prostatic adenocarcinoma]. Arch Esp Urol; 2007 Nov;60(9):1.137-40
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  • [Title] [Metastases in the paranasal sinuses secondary to prostatic adenocarcinoma].
  • [Transliterated title] Metástasis en senos paranasales secundaria a adenocarcinoma prostático.
  • RESULTS: Once the diagnosis was established hormonal maneuvers were performed and chemotherapy with docetaxel was administered achieving at the start of treatment measurable disease stabilization with biochemical remission of PSA levels, followed posteriorly by progression without changes in the metastatic images.
  • The importance of these comes from the extension to the orbit and the eye in vicinity.
  • [MeSH-major] Adenocarcinoma / secondary. Paranasal Sinus Neoplasms / secondary. Prostatic Neoplasms / pathology

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  • (PMID = 18077874.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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7. Saeed MU, Chang BY, Khandwala M, Shivane AG, Chakrabarty A: Twenty year review of histopathological findings in enucleated/eviscerated eyes. J Clin Pathol; 2006 Feb;59(2):153-5
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  • BACKGROUND/AIMS: To evaluate the need for routine histopathological analysis of enucleated/eviscerated eyes and changes in indications for eye removal.
  • Two 10 year periods (1984-93, 1994-2003) were compared to detect changes in indications for eye removal.
  • Ocular trauma was the most frequent diagnosis 1994-2003, followed by phthisis bulbi and endophthalmitis.
  • A fourth case was a diagnostic surprise: adenocarcinoma found in an eye removed for pain and phthisis.
  • There was a significant shift in the diagnosis in the two time periods, and a preference for evisceration in both.
  • [MeSH-major] Eye Diseases / surgery. Eye Enucleation / trends. Eye Evisceration / trends
  • [MeSH-minor] England. Eye Injuries / pathology. Eye Injuries / surgery. Eye Neoplasms / pathology. Eye Neoplasms / surgery. Glaucoma / pathology. Glaucoma / surgery. Humans. Melanoma / pathology. Melanoma / surgery. Retinal Detachment / pathology. Retinal Detachment / surgery. Retrospective Studies. Unnecessary Procedures

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  • [Cites] Eur J Ophthalmol. 2004 Sep-Oct;14(5):363-8 [15506596.001]
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  • (PMID = 16443730.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1860306
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8. Hisham RB, Thuaibah H, Gul YA: Mucinous adenocarcinoma of the rectum with breast and ocular metastases. Asian J Surg; 2006 Apr;29(2):95-7
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  • [Title] Mucinous adenocarcinoma of the rectum with breast and ocular metastases.
  • We present the case of a 32-year-old woman who, 10 months after abdominoperineal resection and total mesorectal excision for a locally advanced mucinous adenocarcinoma of the rectum, presented with local recurrence and metastases to the breast, spine, the left eye and orbit.
  • To the best of our knowledge, breast as well as ocular metastasis in a patient with mucinous adenocarcinoma of the rectum has never been reported and, therefore, needs to be documented.

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  • (PMID = 16644510.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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9. Milman T, Shields JA, Husson M, Marr BP, Shields CL, Eagle RC Jr: Primary ductal adenocarcinoma of the lacrimal gland. Ophthalmology; 2005 Nov;112(11):2048-51
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  • [Title] Primary ductal adenocarcinoma of the lacrimal gland.
  • OBJECTIVE: To report the case of a 59-year-old man with a right lacrimal gland mass, subsequently diagnosed as primary ductal adenocarcinoma of the lacrimal gland.
  • METHODS: We report the clinical presentation, histopathologic and immunohistochemical features, and treatment of a patient with primary ductal adenocarcinoma of the lacrimal gland.
  • RESULTS: Excisional biopsy revealed primary ductal adenocarcinoma of the lacrimal gland.
  • A literature search revealed only 3 prior reports of primary ductal adenocarcinoma of the lacrimal gland.
  • CONCLUSIONS: Although uncommon, primary ductal adenocarcinoma of the lacrimal gland displays characteristic histologic and immunohistochemical findings that allow its distinction from the other primary lacrimal gland adenocarcinomas.
  • [MeSH-major] Carcinoma, Ductal / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology

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  • (PMID = 16271319.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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10. Bansal S, Khan AL, Hsuan J: Lacrimal sac mucus-secreting adenocarcinoma. Orbit; 2008;27(3):199-201
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  • [Title] Lacrimal sac mucus-secreting adenocarcinoma.
  • A forty year old female presented with a swelling above the medial canthal tendon, later diagnosed as a mucus secreting adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus / pathology

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  • (PMID = 18569829.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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11. Betz CS, Leunig A, Janda P, Jund R: [Adenocarcinoma in the tear sack after endonasal dacryocystorhinostomy]. HNO; 2005 Mar;53(3):257-62
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  • [Title] [Adenocarcinoma in the tear sack after endonasal dacryocystorhinostomy].
  • Primary adenocarcinoma of the nasolacrimal drainage system is a highly uncommon diagnosis, which is presumably derived from malignantly transformed glandular cells that are interspersed amongst the epithelium of the nasolacrimal duct.
  • The final histopathological evaluation was adenocarcinoma.
  • The occurrence of adenocarcinoma of the nasolacrimal drainage system in the setting of previous surgery may provide a new insight into the clinical spectrum of the natural history of this disease.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Eye Neoplasms / diagnosis. Eye Neoplasms / therapy. Lacrimal Apparatus / pathology

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  • [Cites] Ophthalmology. 1996 Oct;103(10):1606-12 [8874433.001]
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  • (PMID = 15060716.001).
  • [ISSN] 0017-6192
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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12. Lee WB, Sy HM, Filip DJ, Grossniklaus HE: Metastatic esophageal adenocarcinoma presenting in the iris. Am J Ophthalmol; 2007 Sep;144(3):477-9
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  • [Title] Metastatic esophageal adenocarcinoma presenting in the iris.
  • PURPOSE: To report a case of metastatic esophageal adenocarcinoma presenting as an acute primary iris tumor of unknown origin.
  • RESULTS: Iris biopsy revealed the lesion represented metastasis, and a systemic evaluation later revealed the primary source as esophageal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Esophageal Neoplasms / pathology. Iris Neoplasms / secondary

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  • (PMID = 17765442.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin; 0W860991D6 / Deoxycytidine; 3Z8479ZZ5X / Epirubicin; 6804DJ8Z9U / Capecitabine; U3P01618RT / Fluorouracil
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13. Liard O, Roux L, Thiery G, Calvet P, Moumine M: [Lacrimal adenocarcinoma and anophtalmos]. Rev Stomatol Chir Maxillofac; 2006 Nov;107(5):375-9
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  • [Title] [Lacrimal adenocarcinoma and anophtalmos].
  • [MeSH-major] Adenocarcinoma / diagnosis. Eye Evisceration. Lacrimal Apparatus Diseases / diagnosis
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Eye, Artificial / adverse effects. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Postoperative Complications. Tomography, X-Ray Computed

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  • (PMID = 17128191.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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14. Lee SW, Park SH, Kim IH, Chung H, Kim TY, Heo DS: Nonsurgical treatment of an incompletely excised primary adenocarcinoma of nonpigmented ciliary epithelium. Tumori; 2007 Sep-Oct;93(5):514-7

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  • [Title] Nonsurgical treatment of an incompletely excised primary adenocarcinoma of nonpigmented ciliary epithelium.
  • Primary adenocarcinoma of the nonpigmented ciliary epithelium (NPCE) is a very rare disease and the majority of acquired cases were treated by enucleation.
  • We report the case of a 19-year-old man who had an adenocarcinoma arising from the NPCE.
  • An excisional biopsy was performed and histopathological examination showed primary adenocarcinoma of the NPCE with a positive resection margin.
  • Because of the positive resection margin and to save the eye, radiotherapy rather than enucleation was performed, followed by chemotherapy.
  • Two years after the diagnosis, the patient continues to be followed up without evidence of relapse or cataract change.
  • [MeSH-major] Adenocarcinoma / therapy. Ciliary Body. Uveal Neoplasms / therapy
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Pigment Epithelium of Eye / pathology

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  • (PMID = 18038890.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
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15. Ishida M, Hotta M, Kushima R, Tsuruoka S, Ohji M, Okabe H: Case of ductal adenocarcinoma ex pleomorphic adenoma of the lacrimal gland. Rinsho Byori; 2009 Aug;57(8):746-51
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  • [Title] Case of ductal adenocarcinoma ex pleomorphic adenoma of the lacrimal gland.
  • Ductal adenocarcinoma of the lacrimal gland is extremely rare; to our knowledge, only seven de novo cases and one case of ductal adenocarcinoma ex pleomorphic adenoma have been reported in the literature.
  • Here, we report a case of ductal adenocarcinoma ex pleomorphic adenoma of the lacrimal gland.
  • A 70-year-old Japanese female received the resection of the recurrent lacrimal gland tumor (second surgery), under the clinical diagnosis of recurrent pleomorphic adenoma, fifteen years after the initial surgical resection.
  • The resected tumor was composed of recurrent pleomorphic adenoma and adenocarcinoma.
  • Adenocarcinoma component showed infiltrative papillo-tubular or microcystic growth of carcinoma cells, which had pleomorphic large nuclei with prominent nucleoli and rich eosinophilic cytoplasm.
  • Accordingly, the diagnosis of ductal adenocarcinoma ex pleomorphic adenoma was made.
  • These data suggests that lacrimal ductal adenocarcinoma appears to have a poor prognosis, similar to salivary duct carcinoma, which is one of the most aggressive salivary carcinoma.
  • And further study is needed to clarify the clinicopathological features of the lacrimal ductal adenocarcinoma.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Carcinoma, Ductal, Breast / diagnosis. Carcinoma, Ductal, Breast / pathology. Eye Neoplasms / diagnosis. Eye Neoplasms / pathology. Lacrimal Apparatus. Neoplasms, Multiple Primary

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  • (PMID = 19764409.001).
  • [ISSN] 0047-1860
  • [Journal-full-title] Rinsho byori. The Japanese journal of clinical pathology
  • [ISO-abbreviation] Rinsho Byori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 13
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16. Trichopoulos N, Augsburger JJ, Schneider S: Adenocarcinoma arising from congenital hypertrophy of the retinal pigment epithelium. Graefes Arch Clin Exp Ophthalmol; 2006 Jan;244(1):125-8

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  • [Title] Adenocarcinoma arising from congenital hypertrophy of the retinal pigment epithelium.
  • BACKGROUND: Adenocarcinoma of the retinal pigment epithelium (RPE) is a rare primary malignant intraocular neoplasm.
  • We report a histopathologically confirmed case of adenocarcinoma of the retinal pigment epithelium arising from congenital hypertrophy of the retinal pigment epithelium (CHRPE).
  • RESULTS: Histopathological and immunohistochemical study of the tumor showed it to be an adenocarcinoma of the RPE.
  • CONCLUSIONS: Adenocarcinoma of the RPE arising from CHRPE is extremely rare.
  • [MeSH-major] Adenocarcinoma / pathology. Pigment Epithelium of Eye / pathology. Retinal Neoplasms / pathology

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  • (PMID = 15983818.001).
  • [ISSN] 0721-832X
  • [Journal-full-title] Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
  • [ISO-abbreviation] Graefes Arch. Clin. Exp. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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17. Mensink HW, Mooy C, Paridaens D: In situ adenocarcinoma ex pleomorphic adenoma of the lacrimal gland. Clin Exp Ophthalmol; 2005 Dec;33(6):669-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] In situ adenocarcinoma ex pleomorphic adenoma of the lacrimal gland.
  • A case of an in situ adenocarcinoma of the lacrimal gland that developed in a recurring pleomorphic adenoma is presented.
  • After local excision of the in situ adenocarcinoma ex pleomorphic adenoma, the tumour has been in control for over 6 years.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma in Situ / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology. Neoplasms, Second Primary / pathology

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  • (PMID = 16402969.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Australia
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18. Lee KY, Jap A, Cheah E, Looi A: Orbital metastatic tumour as initial manifestation of asymptomatic gastric adenocarcinoma. Ann Acad Med Singapore; 2006 Oct;35(10):719-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital metastatic tumour as initial manifestation of asymptomatic gastric adenocarcinoma.
  • CLINICAL PICTURE: We report a case, with clinicopathological correlation, of metastatic gastric adenocarcinoma presenting first in the orbit with diplopia.
  • TREATMENT AND RESULTS: Excisional biopsy was performed and histopathology confirmed a metastatic adenocarcinoma.
  • Focused gastrointestinal screening revealed an otherwise asymptomatic Stage IV gastric adenocarcinoma.
  • Histopathological diagnosis can aid localisation of the primary tumour and allow prompt treatment to be instituted.

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  • (PMID = 17102896.001).
  • [ISSN] 0304-4602
  • [Journal-full-title] Annals of the Academy of Medicine, Singapore
  • [ISO-abbreviation] Ann. Acad. Med. Singap.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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19. Zarfoss MK, Dubielzig RR: Metastatic iridociliary adenocarcinoma in a labrador retriever. Vet Pathol; 2007 Sep;44(5):672-6
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  • [Title] Metastatic iridociliary adenocarcinoma in a labrador retriever.
  • An enucleated left eye from a 15-year-old female spayed Labrador Retriever was received by the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) for histopathologic evaluation.
  • There are few reports of canine metastatic iridociliary adenocarcinoma in the literature; this is the first with immunohistochemical analysis.
  • [MeSH-major] Adenocarcinoma / veterinary. Dog Diseases / pathology. Eye Neoplasms / veterinary. Lung Neoplasms / veterinary
  • [MeSH-minor] Animals. Dogs. Eye / pathology. Female. Lung / pathology

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  • (PMID = 17846239.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Schalenbourg A, Coupland S, Kacperek A, Damato B: Iridocyclectomy for neovascular glaucoma caused by proton-beam radiotherapy of pigmented ciliary adenocarcinoma. Graefes Arch Clin Exp Ophthalmol; 2008 Oct;246(10):1499-501
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  • [Title] Iridocyclectomy for neovascular glaucoma caused by proton-beam radiotherapy of pigmented ciliary adenocarcinoma.
  • PURPOSE: To report neovascular glaucoma after proton-beam radiotherapy of an adenocarcinoma of the pigmented ciliary epithelium and its successful treatment by iridocyclectomy.
  • PATIENT AND METHODS: A 65-year-old man developed neovascular glaucoma 10 months after proton-beam radiotherapy of a small pigmented iridociliary tumour with a clinical differential diagnosis of uveal melanoma or adenocarcinoma.
  • The diagnosis of 'toxic tumour syndrome' was made, and iridocyclectomy performed.
  • RESULTS: Histopathology and immunohistochemistry of the specimen diagnosed an adenocarcinoma of the pigmented ciliary epithelium, with the presence of mitoses suggesting residual viable tumour cells.
  • CONCLUSIONS: Neovascular glaucoma after radiotherapy of a small, pigmented, ciliary body tumour raises the possibility of adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / radiotherapy. Ciliary Body / radiation effects. Glaucoma, Neovascular / surgery. Iridectomy. Radiation Injuries / surgery. Radiotherapy, Intensity-Modulated / adverse effects. Uveal Neoplasms / radiotherapy

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  • (PMID = 18581131.001).
  • [ISSN] 0721-832X
  • [Journal-full-title] Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
  • [ISO-abbreviation] Graefes Arch. Clin. Exp. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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21. Inoue M, Watanabe Y, Yamane S, Kobayashi S, Arakawa A, Tsukahara T, Kaneko T, Kadonosono K: Choroidal metastasis with adenocarcinoma of the lung treated with gefitinib. Eur J Ophthalmol; 2010 Sep-Oct;20(5):963-5
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  • [Title] Choroidal metastasis with adenocarcinoma of the lung treated with gefitinib.
  • PURPOSE: To report a case of bilateral regression of choroidal metastasis with adenocarcinoma of the lung treated with gefitinib.
  • METHODS: Retrospective case review of a 68-year-old woman with pulmonary adenocarcinoma with choroidal metastasis who presented with visual loss in the left eye as the initial manifestation.
  • Her visual acuity was 6/6 in the right eye and 6/60 in the left eye before the start of gefitinib administration.
  • RESULTS: Best-corrected visual acuity in the left eye had improved to 6/30 3 months after oral gefitinib.
  • The elevated lesions of the right eye disappeared, with decrease of subretinal fluid and retinal pigment epithelial atrophy.
  • Spectral-domain optical coherence tomography showed that subretinal fluid of the left eye was also reduced.
  • CONCLUSIONS: Oral gefitinib could be effective for regression of choroidal metastasis in patients with adenocarcinoma of the lung and provides a potential treatment option.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Agents / therapeutic use. Choroid Neoplasms / drug therapy. Lung Neoplasms / drug therapy. Quinazolines / therapeutic use

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  • (PMID = 20383850.001).
  • [ISSN] 1724-6016
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Quinazolines; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; S65743JHBS / gefitinib
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22. Kopf B, Ercolani D, Zago S, Bucchi E, Rosti G, Marangolo M: Unilateral retinal detachment as the initial sign of lung adenocarcinoma. J Exp Clin Cancer Res; 2007 Mar;26(1):141-3
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  • [Title] Unilateral retinal detachment as the initial sign of lung adenocarcinoma.
  • We report a case of unilateral retinal detachment as first sign of a moderately differentiated lung adenocarcinoma in a 55-year-old non-smoker that was admitted to the hospital for the first time complaining of a sudden visual loss in the superior fields of the left eye.
  • A CT revealed a slight retinal enlargement of the left eye and a solid mass of about 3 centimeters behind the right pulmonary hilus.
  • Bronchoscopic biopsies were performed with diagnosis of adenocarcinoma of the lung.
  • [MeSH-major] Adenocarcinoma / secondary. Bone Neoplasms / secondary. Lung Neoplasms / diagnosis. Retinal Detachment / etiology. Retinal Neoplasms / secondary

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  • (PMID = 17550143.001).
  • [ISSN] 0392-9078
  • [Journal-full-title] Journal of experimental & clinical cancer research : CR
  • [ISO-abbreviation] J. Exp. Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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23. Lin YW, Chung MT, Lai HC, De Yan M, Shih YL, Chang CC, Yu MH: Methylation analysis of SFRP genes family in cervical adenocarcinoma. J Cancer Res Clin Oncol; 2009 Dec;135(12):1665-74
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  • [Title] Methylation analysis of SFRP genes family in cervical adenocarcinoma.
  • Here, we want to further investigate the methylation status and function of SFRPs in adenocarcinoma of uterine cervix.
  • Then, we used reexpression of SFRP5 in cervical cancer cell lines, HeLa3rd and CaSki, to study the role of SFRP5 in cervical adenocarcinoma by colony formation and invasion assays.
  • RESULTS: The frequency of SFRP genes promoter hypermethylation in adenocarcinoma of cervix samples was 52.2% (12/23), 82.6% (19/23), 65.2% (15/23), and 73.9% (17/23), for SFRP1, SFRP2, SFRP4, and SFRP5, respectively.
  • The frequency of SFRP1, SFRP2, SFRP4, and SFRP5 promoter methylation in adenocarcinoma was significantly higher than in normal control samples (P < 0.001).
  • CONCLUSIONS: Our data suggest that promoter hypermethylation of SFRPs is associated with cervical adenocarcinoma, which could be used for molecular screening of cervical adenocarcinoma in the future.
  • [MeSH-major] Adenocarcinoma / genetics. DNA Methylation. Membrane Proteins / genetics. Uterine Cervical Neoplasms / genetics
  • [MeSH-minor] Eye Proteins / genetics. Eye Proteins / physiology. Female. Gene Expression Regulation, Neoplastic. HeLa Cells. Humans. Intercellular Signaling Peptides and Proteins / chemistry. Intercellular Signaling Peptides and Proteins / genetics. Multigene Family / genetics. Neoplasm Invasiveness. Promoter Regions, Genetic. Sequence Analysis, DNA. Transfection. Tumor Cells, Cultured

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  • (PMID = 19513747.001).
  • [ISSN] 1432-1335
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Eye Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / SFRP1 protein, human; 0 / SFRP5 protein, human
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24. Foo FY, Lee M, Looi A: Asymptomatic pancreatic adenocarcinoma presenting as an orbital metastatic tumor. Orbit; 2010 Oct;29(5):262-5
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  • [Title] Asymptomatic pancreatic adenocarcinoma presenting as an orbital metastatic tumor.
  • We report a rare case, with clinicopathological correlation, of metastatic pancreatic adenocarcinoma, presenting first in the orbit with symptoms of diplopia, blurring of vision and supraorbital ache.
  • Excisional biopsy was performed and histopathology confirmed a metastatic adenocarcinoma.
  • Subsequent gastrointestinal imaging and tumor markers revealed an asymptomatic pancreatic adenocarcinoma, with multiple liver metastases.
  • Our patient developed hepatobiliary sepsis and passed away 44 days after diagnosis.
  • [MeSH-major] Adenocarcinoma / secondary. Orbital Neoplasms / secondary. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Diplopia / diagnosis. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed. Vision Disorders / diagnosis

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  • (PMID = 20704487.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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25. Ho CM, Lai HC, Huang SH, Chien TY, Lin MC, Chang SF: Promoter methylation of sFRP5 in patients with ovarian clear cell adenocarcinoma. Eur J Clin Invest; 2010 Apr;40(4):310-8
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  • [Title] Promoter methylation of sFRP5 in patients with ovarian clear cell adenocarcinoma.
  • BACKGROUND: Specific tumour suppressor genes with promoter methylation in ovarian clear cell adenocarcinoma (OCCA) can be one important epigenetic mark distinguishing OCCA from ovarian serous adenocarcinoma (OSA), benign endometriotic cysts and normal ovarian epitheliums.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. DNA Methylation. Eye Proteins. Membrane Proteins. Ovarian Neoplasms / pathology


26. Akcaer M, Milman T, Finger PT: Imaging of endometrioid adenocarcinoma of the uterus metastatic to the ciliary body. Ophthalmic Surg Lasers Imaging; 2008 May-Jun;39(3):246-9
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  • [Title] Imaging of endometrioid adenocarcinoma of the uterus metastatic to the ciliary body.
  • A 60-year-old woman with endometrioid adenocarcinoma (stage FIGO II) presented with left eye pain.
  • A Finger iridectomy technique ciliary body tumor biopsy revealed metastatic endometrioid adenocarcinoma.
  • This is the first reported case of endometrioid adenocarcinoma of the uterus metastatic to the uveal tract.
  • [MeSH-major] Carcinoma, Endometrioid / diagnosis. Carcinoma, Endometrioid / secondary. Ciliary Body. Endometrial Neoplasms / pathology. Uveal Neoplasms / diagnosis. Uveal Neoplasms / secondary

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  • (PMID = 18556953.001).
  • [ISSN] 1542-8877
  • [Journal-full-title] Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
  • [ISO-abbreviation] Ophthalmic Surg Lasers Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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27. Heindl LM, Naumann GO, Kruse FE, Holbach LM: Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21. Br J Ophthalmol; 2008 Mar;92(3):389-91
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  • [Title] Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21.
  • This case report describes a 37-year-old man with a blind eye with opaque media.
  • Histopathology revealed an aggressive adenocarcinoma of the retinal pigment epithelium with marked invasion of the choroid, retina, sclera and--not previously reported--the orbital and cranial optic nerve and subarachnoid space.
  • Adenocarcinoma of the retinal pigment epithelium, which occurs rarely in longstanding blind eyes, may exhibit aggressive behaviour with life-threatening risk of metastatic spread.
  • [MeSH-major] Adenocarcinoma / secondary. Down Syndrome. Pigment Epithelium of Eye. Retinal Neoplasms / pathology
  • [MeSH-minor] Adult. Brain Neoplasms / secondary. Eye / pathology. Fatal Outcome. Humans. Male. Neoplasm Invasiveness. Spinal Cord Neoplasms / secondary

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  • [CommentIn] Br J Ophthalmol. 2009 Feb;93(2):276 [19174409.001]
  • (PMID = 18303161.001).
  • [ISSN] 1468-2079
  • [Journal-full-title] The British journal of ophthalmology
  • [ISO-abbreviation] Br J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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28. Brannan PA, Kersten RC, Schneider S, Kulwin DR: A case of primary adenocarcinoma of the lacrimal sac. Orbit; 2005 Dec;24(4):291-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of primary adenocarcinoma of the lacrimal sac.
  • PURPOSE: To present a rare case of adenocarcinoma arising from the lacrimal sac.
  • METHODS: Report of a new case of primary lacrimal sac adenocarcinoma.
  • RESULTS: The clinical presentation, workup, surgical treatment and pathology of a case of adenocarcinoma of the lacrimal sac are described.
  • CONCLUSION: Although very rare, these tumors should be in the differential diagnosis of any lacrimal sac mass, especially those presenting above the medial canthal tendon.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Eye Neoplasms / diagnosis. Eye Neoplasms / surgery. Lacrimal Apparatus Diseases / diagnosis. Lacrimal Apparatus Diseases / surgery

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  • (PMID = 16354642.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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29. Ahn JY, Chang JH, Kim SH, Lee KS: Pleomorphic adenocarcinoma of the lacrimal gland with multiple intracranial and spinal metastases. World J Surg Oncol; 2007;5:29
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  • [Title] Pleomorphic adenocarcinoma of the lacrimal gland with multiple intracranial and spinal metastases.
  • CONCLUSION: It is important to recognize that leptomeningeal intracranial and spinal disseminations of pleomorphic adenocarcinoma can occur, although it is extremely rare.
  • To our knowledge, we report the first case of pleomorphic adenocarcinoma of the lacrimal gland presumably metastasizing to the intracranium and spine.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Pleomorphic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus / pathology. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery

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  • [Cites] Br J Radiol. 1981 Dec;54(648):1034-8 [7296228.001]
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  • (PMID = 17341319.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1820784
  • [General-notes] NLM/ Original DateCompleted: 20070810
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30. Zhang J, Jianmin, Wang N, Shi J, Ge X: A case of primary oncocytic adenocarcinoma of the lacrimal sac. BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of primary oncocytic adenocarcinoma of the lacrimal sac.
  • Here we report a case of primary oncocytic adenocarcinoma of the lacrimal sac in a 56-year-old man.

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  • [Cites] Orbit. 2005 Dec;24(4):291-3 [16354642.001]
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  • (PMID = 21747898.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3029480
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31. Zou H, Molina JR, Harrington JJ, Osborn NK, Klatt KK, Romero Y, Burgart LJ, Ahlquist DA: Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus. Int J Cancer; 2005 Sep 10;116(4):584-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus.
  • Hypermethylation of secreted frizzled-related proteins (SFRP) genes frequently occurs with several cancers but has not been studied in esophageal adenocarcinoma or its precursor-Barrett's esophagus.
  • The mRNA expression of SFRP genes was quantified by real-time reverse-transcription PCR in esophageal adenocarcinoma cell lines with and without demethylation by 5-aza-2'deoxycytidine and inhibition of deacetylation by trichostatin A treatment.
  • Thus, hypermethylation of SFRP genes is a common early event in the evolution of esophageal adenocarcinoma, and methylation of SFRP1, 4 and 5 might serve as biomarkers for Barrett's neoplasia.
  • Aberrant promoter methylation appears to functionally silence SFRP gene expression in esophageal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / genetics. Adenocarcinoma / pathology. Barrett Esophagus / genetics. Barrett Esophagus / pathology. DNA Methylation. Esophageal Neoplasms / genetics. Esophageal Neoplasms / pathology. Eye Proteins / genetics. Eye Proteins / metabolism. Gene Expression Profiling. Intercellular Signaling Peptides and Proteins / genetics. Intercellular Signaling Peptides and Proteins / metabolism. Membrane Proteins / genetics. Membrane Proteins / metabolism. Proto-Oncogene Proteins / genetics. Proto-Oncogene Proteins / metabolism

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  • [Copyright] (c) 2005 Wiley-Liss, Inc.
  • (PMID = 15825175.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Eye Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / Proto-Oncogene Proteins; 0 / RNA, Messenger; 0 / SFRP1 protein, human; 0 / SFRP4 protein, human; 0 / SFRP5 protein, human
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32. Nakas A, Klimatsidas MN, Entwisle J, Martin-Ucar AE, Waller DA: Video-assisted versus open pulmonary metastasectomy: the surgeon's finger or the radiologist's eye? Eur J Cardiothorac Surg; 2009 Sep;36(3):469-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Video-assisted versus open pulmonary metastasectomy: the surgeon's finger or the radiologist's eye?
  • METHODS: Pulmonary metastasectomy was performed for metastatic colorectal adenocarcinoma in 52 patients: 27 open and 25 VATS over 8 years.
  • CONCLUSIONS: The selective use of VATS therapeutic metastasectomy in conjunction with multi-detector CT is justified in metastatic colorectal adenocarcinoma.
  • Trust the radiologist's eye.
  • [MeSH-major] Adenocarcinoma / secondary. Adenocarcinoma / surgery. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Thoracic Surgery, Video-Assisted / methods

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  • (PMID = 19464921.001).
  • [ISSN] 1873-734X
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Germany
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33. Hendrix DV, Donnell RL: Lenticular invasion by a ciliary body adenocarcinoma in a dog. Vet Pathol; 2007 Jul;44(4):540-2
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  • [Title] Lenticular invasion by a ciliary body adenocarcinoma in a dog.
  • Evaluation of the right eye of a 10-year-old Labrador Retriever revealed a ciliary body mass spanning from the 10 o'clock to 2 o'clock position that was impinging on the lens.
  • Histologic evaluation of the enucleated eye revealed a ciliary body adenocarcinoma with lens invasion.
  • [MeSH-major] Adenocarcinoma / veterinary. Ciliary Body / pathology. Dog Diseases / pathology. Lens, Crystalline / pathology. Uveal Neoplasms / veterinary

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  • (PMID = 17606520.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Kurisu Y, Shibayama Y, Tsuji M, Kurokawa A, Akutagawa H, Egashira Y, Matsuo T, Itabashi T: A case of primary ductal adenocarcinoma of the lacrimal gland: histopathological and immunohistochemical study. Pathol Res Pract; 2005;201(1):49-53
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  • [Title] A case of primary ductal adenocarcinoma of the lacrimal gland: histopathological and immunohistochemical study.
  • We encountered primary ductal adenocarcinoma of the lacrimal gland in a 67-year-old Japanese man.
  • To the best of our knowledge, only three cases of primary ductal adenocarcinoma of the lacrimal gland have been reported in the literature.
  • The mass was resected, and primary ductal adenocarcinoma of the lacrimal gland was diagnosed histopathologically.
  • It was not clear whether the ductal adenocarcinoma originated from the ductal or acinar epithelium of the lacrimal gland, because the immunohistochemical features of both epithelia were identical.
  • [MeSH-major] Carcinoma, Ductal / metabolism. Carcinoma, Ductal / pathology. Eye Neoplasms / metabolism. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / metabolism. Lacrimal Apparatus Diseases / pathology

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  • (PMID = 15807311.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 68238-35-7 / Keratins
  • [Number-of-references] 14
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35. Braun U, Grest P, Jehle W, Kaps S, Spiess B: [Intraocular hemorrhage in a goat with thrombocytopenia and metastasis of an adenocarcinoma in the iris]. Schweiz Arch Tierheilkd; 2008 Jul;150(7):359-62
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  • [Title] [Intraocular hemorrhage in a goat with thrombocytopenia and metastasis of an adenocarcinoma in the iris].
  • This case report describes the findings in a 10-year-old goat with metastasis of an adenocarcinoma in the iris.
  • Two weeks before admission, the owner had noticed blepharospasm of the left eye.
  • There was mild corneal oedema of the left eye.
  • All other internal parts of the eye could not be seen.
  • Ultrasonography of the left eye confirmed cloudiness of the anterior chamber and revealed moderate thickening of the iris.
  • The anterior chamber of the left eye contained blood, and the iris was thicker than normal and adhered to the posterior surface of the cornea.
  • Histologically, a diagnosis of carcinoma was confirmed, but the origin of the tumour could not be determined.
  • [MeSH-major] Adenocarcinoma / veterinary. Eye Hemorrhage / veterinary. Goat Diseases / diagnosis. Iris Neoplasms / veterinary

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  • (PMID = 18714940.001).
  • [ISSN] 0036-7281
  • [Journal-full-title] Schweizer Archiv für Tierheilkunde
  • [ISO-abbreviation] Schweiz. Arch. Tierheilkd.
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Switzerland
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36. Sahin A, Kiratli H: Choroidal metastasis as a first sign of recurrence in a patient with gastric adenocarcinoma. Can J Ophthalmol; 2007 Apr;42(2):331-2
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  • [Title] Choroidal metastasis as a first sign of recurrence in a patient with gastric adenocarcinoma.
  • CASE REPORT: A 40-year-old man with a history of gastric adenocarcinoma presented with progressive visual loss in his right eye.
  • COMMENTS: This patient represents a rare occurrence of metastatic gastric adenocarcinoma to the choroid and optic nerve, developing as a first sign of systemic recurrence.

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  • (PMID = 17392868.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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37. Galatoire O, Hamédani M, Putterman M, Berges O, Morax S: [Adenocarcinoma in a pleomorphic adenoma of the lacrimal gland: a case study]. J Fr Ophtalmol; 2005 Oct;28(8):896-901
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  • [Title] [Adenocarcinoma in a pleomorphic adenoma of the lacrimal gland: a case study].
  • PURPOSE: To report a patient with an adenocarcinoma in a pleomorphic adenoma of the lacrimal gland.
  • Adenocarcinoma constitutes a distinct group of epithelial malignancies of the lacrimal gland.
  • The final specimen showed an adenocarcinoma in a pleomorphic adenoma.
  • CONCLUSION: Although adenocarcinoma has rarely been reported in association with a pleomorphic adenoma of the lacrimal gland, this combination can exist.
  • [MeSH-major] Adenocarcinoma. Adenoma, Pleomorphic. Eye Neoplasms. Lacrimal Apparatus. Neoplasms, Multiple Primary

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  • (PMID = 16249774.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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38. Tanaka K: A case of metastases to the paranasal sinus from rectal mucinous adenocarcinoma. Int J Clin Oncol; 2006 Feb;11(1):64-5

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  • [Title] A case of metastases to the paranasal sinus from rectal mucinous adenocarcinoma.
  • We report a case of metastases to the paranasal sinus from rectal adenocarcinoma.
  • A 72-year-old woman, who had a history of therapy with rectal adenocarcinoma, came to our hospital for visual loss in her right eye.
  • From the surgical specimen, we found that the tumor was a metastasis of a previously managed rectal mucinous adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Paranasal Sinus Neoplasms / secondary. Rectal Neoplasms / pathology

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  • (PMID = 16508732.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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39. Rückert F, Hennig M, Petraki CD, Wehrum D, Distler M, Denz A, Schröder M, Dawelbait G, Kalthoff H, Saeger HD, Diamandis EP, Pilarsky C, Grützmann R: Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma. Br J Cancer; 2008 Nov 4;99(9):1484-92
The Lens. Cited by Patents in .

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  • [Title] Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma.
  • Previous studies suggested an upregulation of KLK10 and KLK6 in pancreatic ductal adenocarcinoma (PDAC).
  • [MeSH-major] Adenocarcinoma / chemistry. Carcinoma, Pancreatic Ductal / chemistry. Kallikreins / analysis. Pancreatic Neoplasms / chemistry
  • [MeSH-minor] Cell Line, Tumor. Cell Movement. Eye Proteins / physiology. Gene Expression Profiling. Gene Silencing. Humans. Immunohistochemistry. Nerve Growth Factors / physiology. Prognosis. Serpins / physiology

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  • (PMID = 18854834.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Eye Proteins; 0 / Nerve Growth Factors; 0 / Serpins; 0 / pigment epithelium-derived factor; EC 3.4.21.- / KLK10 protein, human; EC 3.4.21.- / KLK6 protein, human; EC 3.4.21.- / Kallikreins
  • [Other-IDs] NLM/ PMC2579692
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40. Kaur H, Buettner H, Salomao DR, Marks RS: Transcleral orbital invasion by a radiation and chemotherapy-resistant choroidal metastasis of a pulmonary adenocarcinoma. Am J Ophthalmol; 2007 Feb;143(2):369-70
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  • [Title] Transcleral orbital invasion by a radiation and chemotherapy-resistant choroidal metastasis of a pulmonary adenocarcinoma.
  • PURPOSE: To report transcleral orbital invasion by a radiation- and chemotherapy-resistant choroidal metastasis of a pulmonary adenocarcinoma.
  • METHODS: A 51-year-old female was found to have choroidal metastasis from a previously unknown primary pulmonary adenocarcinoma.
  • RESULTS: A transvitreal aspiration biopsy of the choroidal lesion confirmed the diagnosis of metastatic pulmonary adenocarcinoma.
  • CONCLUSIONS: Despite appropriate external beam radiation therapy (EBRT) and chemotherapy, pulmonary adenocarcinoma metastases to the choroid can continue to grow and may invade the orbit transclerally.
  • [MeSH-major] Adenocarcinoma / secondary. Choroid Neoplasms / secondary. Lung Neoplasms / pathology. Orbital Neoplasms / pathology. Sclera / pathology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carboplatin / administration & dosage. Chemotherapy, Adjuvant. Deoxycytidine / administration & dosage. Deoxycytidine / analogs & derivatives. Drug Resistance. Eye Enucleation. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Neoplasm Invasiveness. Radiation Tolerance. Radiotherapy Dosage

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  • (PMID = 17258542.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine; BG3F62OND5 / Carboplatin
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41. Primavera V, Querques G, Guigui B, Turco I, Iaculli C, Russo V, Delle Noci N: [Choroidal metastasis from clinically regressed prostate adenocarcinoma: imaging of a rare case]. J Fr Ophtalmol; 2008 Nov;31(9):877-82
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  • [Title] [Choroidal metastasis from clinically regressed prostate adenocarcinoma: imaging of a rare case].
  • We report a rare case of prostatic adenocarcinoma metastases at the choroids, diagnosed and followed by fluorescein angiography (FA), indocyanine-green angiography (ICGA), and optical coherence tomography (OCT-3 Stratus).
  • OBSERVATION: A 54-year-old man was referred to our department for decreased vision in his left eye lasting for 1 month.
  • On ophthalmic evaluation, best corrected visual acuity (BCVA) was 20/20 in his right eye and 20/63 in his left eye.
  • Biomicroscopic examination of the anterior segments did not reveal anything abnormal in either eye.
  • The systemic workup, including hematologic analysis and total-body computed tomography (CT), revealed elevated serum prostate-specific antigen (PSA) and alkaline phosphatase, extensive abnormalities of the axial skeleton, and nodular pulmonary shadows; therefore, prostatic adenocarcinoma was suspected.
  • Needle biopsies (prostatic and pulmonary) confirmed adenocarcinoma of the prostate, with metastatic disease.
  • Fluorescein angiography, indocyanine-green angiography, and optical coherence tomography are useful tools in the diagnosis and follow-up of prostatic adenocarcinoma metastatic to the choroid.
  • [MeSH-major] Adenocarcinoma / secondary. Choroid Neoplasms / secondary. Prostatic Neoplasms / pathology

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  • (PMID = 19107059.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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42. Segal A, Segal N, Gal A, Tumuluri K: Mucinous sweat gland adenocarcinoma of the eyelid - current knowledge of a rare tumor. Orbit; 2010 Dec;29(6):334-40

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  • [Title] Mucinous sweat gland adenocarcinoma of the eyelid - current knowledge of a rare tumor.
  • PURPOSE: To review the medical literature on mucinous sweat gland adenocarcinoma of the eyelid (MSA) and present two new cases.
  • In 12(21.8%) patients a lesion with a benign diagnosis was previously excised from the same location.
  • In 2 of them histological re-examination resulted in a diagnosis of MSA.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Eyelid Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 21158574.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
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43. Furukawa N, Oi H, Yoshida S, Shigetomi H, Kanayama S, Kobayashi H: The usefulness of photodynamic eye for sentinel lymph node identification in patients with cervical cancer. Tumori; 2010 Nov-Dec;96(6):936-40
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  • [Title] The usefulness of photodynamic eye for sentinel lymph node identification in patients with cervical cancer.
  • When the operation was advanced to the pelvis, near-infrared fluorescence imaging was performed using photodynamic eye (Hamamatsu Photonics Co., Japan).
  • The median maximum tumor diameter of dissected cervical tumors was 35 mm (22-65); histology was squamous cell carcinoma in 8 patients and adenocarcinoma in 2 patients.
  • CONCLUSIONS: Photodynamic eye achieved a detection rate similar to that obtained with the blue dye and radioisotope method.
  • [MeSH-minor] Adenocarcinoma / pathology. Adult. Aged. Carcinoma, Squamous Cell / pathology. Coloring Agents. Female. Humans. Indocyanine Green. Lymphatic Metastasis. Middle Aged. Photochemotherapy


44. Negahban S, Daneshbod Y, Khademi B, Rasekhi AR, Soleimanpour H: Sinonasal clear cell adenocarcinoma: a case report. Acta Cytol; 2009 Sep-Oct;53(5):597-600

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sinonasal clear cell adenocarcinoma: a case report.
  • We present cytologic findings of clear cell sinonasal adenocarcinoma and related pitfalls.
  • CASE: A 52-year-old woman presented with a left-cheek facial mass of 3-4 years' duration, with progressive enlargement, nasal discharge and discoloration of the lateral side of her left eye.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Nasal Mucosa / pathology. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 19798893.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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45. Richter JC, Waldegg G, Richter KK: [Red eye and visual impairment two months after esophageal resection with complicated postoperative course]. Praxis (Bern 1994); 2008 Oct 8;97(20):1091-5
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  • [Title] [Red eye and visual impairment two months after esophageal resection with complicated postoperative course].
  • A patient with a red, painful eye and gradual visual impairment is examined ophthalmologically.
  • Diagnosis and treatment of candidemia with a focus on candida endophthalmitis is discussed.
  • [MeSH-major] Adenocarcinoma / surgery. Candida tropicalis. Candidiasis / diagnosis. Cardia / surgery. Conjunctivitis / etiology. Endophthalmitis / diagnosis. Esophageal Neoplasms / surgery. Esophagectomy. Postoperative Complications / diagnosis. Postoperative Complications / etiology. Stomach Neoplasms / surgery. Vision, Low / etiology
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male


46. Hayashi K, Hatsuno K, Yoshimura R, Iida T, Ayukawa F, Toda K, Taniguchi H, Shibuya H: Electron therapy for orbital and periorbital lesions using customized lead eye shields. Ophthalmologica; 2009;223(2):96-101
Hazardous Substances Data Bank. Lead, elemental .

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  • [Title] Electron therapy for orbital and periorbital lesions using customized lead eye shields.
  • PURPOSE: To establish the protective efficacy against late complications of electron therapy using customized lead eye shields in cases with orbital and periorbital lesions.
  • Customized lead eye shields were prepared and placed in the respective patients' eyes during each fraction of electron therapy.
  • RESULTS: The preparation period for the customized lead eye shields was 2 days.
  • CONCLUSION: Customized lead eye shields could be made relatively quickly, and electron therapy for orbital and periorbital lesions could be undertaken safely without any late complication.
  • [MeSH-major] Eye Protective Devices. Lead. Lymphoma / radiotherapy. Orbital Neoplasms / radiotherapy. Radiation Protection / instrumentation. Radiotherapy / methods
  • [MeSH-minor] Adenocarcinoma / radiotherapy. Adult. Aged. Aged, 80 and over. Electrons. Equipment Design. Eyelid Neoplasms / radiotherapy. Female. Follow-Up Studies. Humans. Male. Meibomian Glands. Middle Aged

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  • [Copyright] 2008 S. Karger AG, Basel.
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  • (PMID = 19033716.001).
  • [ISSN] 1423-0267
  • [Journal-full-title] Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
  • [ISO-abbreviation] Ophthalmologica
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 2P299V784P / Lead
  • [Other-IDs] NLM/ PMC2790777
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47. Grünbaum M, Ervens J, Stein H, Loddenkemper C: [Primary ductal adenocarcinoma near the orbit]. Pathologe; 2010 Jul;31(4):279-82

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary ductal adenocarcinoma near the orbit].
  • The morphological and immunohistochemical findings led to the diagnosis of a primary ductal carcinoma resembling salivary duct carcinoma (SDC).
  • The tumor could be removed without compromising the eye.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Calcinosis / pathology. Calcinosis / surgery. Combined Modality Therapy. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Orbit / pathology. Orbit / surgery. Radiotherapy, Adjuvant. Receptors, Androgen / analysis

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  • (PMID = 20552200.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Androgen
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48. Goto A, Kusumi M, Wakutani Y, Nakaso K, Kowa H, Nakashima K: [Anti-Yo antibody associated paraneoplastic cerebellar degeneration with gastric adenocarcinoma in a male patient: a case report]. Rinsho Shinkeigaku; 2006 Feb;46(2):144-7
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  • [Title] [Anti-Yo antibody associated paraneoplastic cerebellar degeneration with gastric adenocarcinoma in a male patient: a case report].
  • We report a 71-year-old man presenting with paraneoplastic cerebellar degeneration (PCD) associated anti-Yo antibody after surgery for gastric adenocarcinoma.
  • When he was hospitalized, he showed a disturbance of his eye movement on lower gaze, a nystagmus on lateral gaze, saccadic eye movement on smooth pursuit, cerebellar ataxia, and decreasing of muscle tonus in his extremities.
  • These findings suggest that PCD associated with anti-Yo antibody triggered by adenocarcinoma might occur in this male patient.
  • [MeSH-major] Adenocarcinoma / surgery. Autoantibodies / analysis. Paraneoplastic Cerebellar Degeneration / immunology. Purkinje Cells / immunology. Stomach Neoplasms / surgery

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  • (PMID = 16619840.001).
  • [ISSN] 0009-918X
  • [Journal-full-title] Rinshō shinkeigaku = Clinical neurology
  • [ISO-abbreviation] Rinsho Shinkeigaku
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Autoantibodies
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49. Scott AW, Cummings TJ, Kirkpatrick JP, Mruthyunjaya P: Choroidal metastasis of follicular thyroid adenocarcinoma diagnosed by 25-gauge transretinal biopsy. Ann Ophthalmol (Skokie); 2008;40(2):110-2
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  • [Title] Choroidal metastasis of follicular thyroid adenocarcinoma diagnosed by 25-gauge transretinal biopsy.
  • A 25-gauge vitrector was used to perform transretinal choroidal biopsy (TRCB), confirming the diagnosis of metastatic follicular thyroid carcinoma.
  • [MeSH-major] Adenocarcinoma, Follicular / secondary. Choroid Neoplasms / secondary. Thyroid Neoplasms / pathology

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  • (PMID = 19013920.001).
  • [ISSN] 1530-4086
  • [Journal-full-title] Annals of ophthalmology (Skokie, Ill.)
  • [ISO-abbreviation] Ann Ophthalmol (Skokie)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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50. Tsiambas E, Karameris A, Dervenis C, Lazaris AC, Giannakou N, Gerontopoulos K, Patsouris E: HER2/neu expression and gene alterations in pancreatic ductal adenocarcinoma: a comparative immunohistochemistry and chromogenic in situ hybridization study based on tissue microarrays and computerized image analysis. JOP; 2006;7(3):283-94
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  • [Title] HER2/neu expression and gene alterations in pancreatic ductal adenocarcinoma: a comparative immunohistochemistry and chromogenic in situ hybridization study based on tissue microarrays and computerized image analysis.
  • CONTEXT: HER2/neu overexpression is observed in many cancers including pancreatic ductal adenocarcinoma.
  • The immunostained slides were evaluated by conventional eye microscopy and digital image analysis.
  • Significant improvement in interobserver agreement (kappa=0.76 vs. 0.94) was achieved correlating the immunohistochemical results obtained by conventional eye and digital microscopy, especially in the cases of overexpression (2+, 3+).
  • Furthermore, evaluation of HER2/neu protein expression based on digital image analysis and not only on conventional eye microscopy improves the accuracy and reliability of immunohistochemical estimation, although that does not demonstrate clinical significance and prognostic value in pancreatic ductal adenocarcinoma.

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  • (PMID = 16685109.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] EC 2.7.10.1 / Receptor, ErbB-2
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51. Shieh YS, Lai CY, Kao YR, Shiah SG, Chu YW, Lee HS, Wu CW: Expression of axl in lung adenocarcinoma and correlation with tumor progression. Neoplasia; 2005 Dec;7(12):1058-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of axl in lung adenocarcinoma and correlation with tumor progression.
  • [MeSH-major] Adenocarcinoma / enzymology. Lung Neoplasms / enzymology. Oncogene Proteins / metabolism. Receptor Protein-Tyrosine Kinases / metabolism

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  • [Cites] Am J Pathol. 1999 Apr;154(4):1171-80 [10233855.001]
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  • (PMID = 16354588.001).
  • [ISSN] 1522-8002
  • [Journal-full-title] Neoplasia (New York, N.Y.)
  • [ISO-abbreviation] Neoplasia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Oncogene Proteins; 0 / Proto-Oncogene Proteins; 0 / RNA, Small Interfering; EC 2.7.10.1 / Receptor Protein-Tyrosine Kinases; EC 2.7.10.1 / axl receptor tyrosine kinase
  • [Other-IDs] NLM/ PMC1501169
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52. Banneux N, Bonnet S: [Optic disc metastasis from pulmonary adenocarcinoma]. Bull Soc Belge Ophtalmol; 2007;(305):79-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Optic disc metastasis from pulmonary adenocarcinoma].
  • OBSERVATION: We report the case of a 65 year-old man presenting an unilateral impairment of visual acuity at the left eye.
  • The diagnosis of an optic disc metastasis was retained according to the ophthalmoscopy and various complementary investigations.
  • The mean age at the time of ocular diagnosis is 55 years.
  • The mean survival is 13 months after ocular diagnosis.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / secondary. Lung Neoplasms / pathology. Optic Nerve Neoplasms / diagnosis. Optic Nerve Neoplasms / secondary

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  • (PMID = 18018431.001).
  • [ISSN] 0081-0746
  • [Journal-full-title] Bulletin de la Société belge d'ophtalmologie
  • [ISO-abbreviation] Bull Soc Belge Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
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53. Lang D, Mascarenhas JB, Powell SK, Halegoua J, Nelson M, Ruggeri BA: PAX6 is expressed in pancreatic adenocarcinoma and is downregulated during induction of terminal differentiation. Mol Carcinog; 2008 Feb;47(2):148-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] PAX6 is expressed in pancreatic adenocarcinoma and is downregulated during induction of terminal differentiation.
  • [MeSH-major] Adenocarcinoma / genetics. Cell Differentiation / genetics. Eye Proteins / genetics. Homeodomain Proteins / genetics. Paired Box Transcription Factors / genetics. Pancreatic Neoplasms / genetics. Repressor Proteins / genetics

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  • (PMID = 17849422.001).
  • [ISSN] 1098-2744
  • [Journal-full-title] Molecular carcinogenesis
  • [ISO-abbreviation] Mol. Carcinog.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / Eye Proteins; 0 / Homeodomain Proteins; 0 / PAX6 protein; 0 / Paired Box Transcription Factors; 0 / Repressor Proteins; 0 / Tumor Suppressor Protein p53
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54. Gonçalves AC, Costa PG, Monteiro ML: [Inferior rectus muscle metastasis as a presenting sign of renal cell carcinoma: case report]. Arq Bras Oftalmol; 2006 May-Jun;69(3):435-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Metástase no músculo reto inferior como sinal de apresentação de adenocarcinoma renal: relato de caso.
  • Although dysthyroid ophthalmopathy is the most common cause of enlargement of extraocular muscles, the differential diagnosis is extensive.
  • A biopsy of the lesion followed by systemic evaluation established the diagnosis of metastatic renal cell carcinoma.
  • There are few cases of metastatic tumors to the extraocular muscles reported in the literature and thus our objective is to report a new case, review the literature and reiterate the inclusion of this disorder in the differential diagnosis of enlargement of the extraocular muscles.
  • [MeSH-major] Carcinoma, Renal Cell / secondary. Eye Neoplasms / secondary. Kidney Neoplasms / pathology. Muscle Neoplasms / secondary. Oculomotor Muscles / pathology
  • [MeSH-minor] Diagnosis, Differential. Diplopia / etiology. Exophthalmos / etiology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 16936974.001).
  • [ISSN] 0004-2749
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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55. Kannan V, Sathiyanarayanan VK, Sagde S, Anand V, Almel S, Kapadia A, Srinivas V: Three dimensional conformal radiation therapy in prostate adenocarcinoma: survival and rectal toxicity. J Cancer Res Ther; 2005 Jan-Mar;1(1):34-7
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  • [Title] Three dimensional conformal radiation therapy in prostate adenocarcinoma: survival and rectal toxicity.
  • Treatment method consisted of pelvis and leg immobilization, planning CT scan, marking of planning target volume and organs at risk and 3D beam plan using multileaf collimated beam shaping through beam's eye view display.
  • [MeSH-major] Adenocarcinoma / radiotherapy. Prostatic Neoplasms / radiotherapy. Rectum / radiation effects

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  • (PMID = 17998623.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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56. Beaugerie L, Sokol H, Seksik P: Noncolorectal malignancies in inflammatory bowel disease: more than meets the eye. Dig Dis; 2009;27(3):375-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Noncolorectal malignancies in inflammatory bowel disease: more than meets the eye.
  • In patients with Crohn's disease, the risk of small bowel adenocarcinoma is 20-40 times higher than the low background risk of the general population.
  • In the subset of patients with longstanding small bowel lesions, the absolute risk of small bowel adenocarcinoma exceeds 1 per 100 patient-years after 25 years of follow-up and becomes equivalent to the risk of colorectal cancer.
  • Growing evidence suggests that the pathogenesis of small bowel adenocarcinoma arising in inflammatory lesions of Crohn's disease is similar to that of colorectal cancer complicating chronic colonic inflammation (inflammation-dysplasia-cancer sequence).
  • However, contrasting with the established endoscopic detection of colonic advanced neoplasias in patients with longstanding extensive colitis, there is no consensus at this time how to face the excess-risk of small bowel adenocarcinoma in patients at high risk.

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  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19786768.001).
  • [ISSN] 1421-9875
  • [Journal-full-title] Digestive diseases (Basel, Switzerland)
  • [ISO-abbreviation] Dig Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 46
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57. Mignanelli ED, de Campos-Lobato LF, Stocchi L, Lavery IC, Dietz DW: Downstaging after chemoradiotherapy for locally advanced rectal cancer: is there more (tumor) than meets the eye? Dis Colon Rectum; 2010 Mar;53(3):251-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Downstaging after chemoradiotherapy for locally advanced rectal cancer: is there more (tumor) than meets the eye?
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Rectal Neoplasms / pathology. Rectal Neoplasms / surgery

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  • [ErratumIn] Dis Colon Rectum. 2010 Jun;53(6):960. Campos-Lobato, Luiz F [corrected to de Campos-Lobato, Luiz F]
  • (PMID = 20173469.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Shields JA, Eagle RC Jr, Shields CL, Brown GC, Lally SE: Malignant transformation of congenital hypertrophy of the retinal pigment epithelium. Ophthalmology; 2009 Nov;116(11):2213-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: To report a clinicopathologic correlation of an adenocarcinoma that arose from solitary congenital hypertrophy of the retinal pigment epithelium (CHRPE).
  • METHODS: A 56-year-old black woman was referred for an asymptomatic fundus lesion in her left eye.
  • It had features typical of CHRPE, but there was a small elevated nodule within the flat component, and the diagnosis was adenoma of the retinal pigment epithelium (RPE) arising from CHRPE.
  • Thirteen years after the initial diagnosis, the patient returned with severe visual loss and no view of the fundus resulting from cataract and posterior synechia.
  • The eye was enucleated and studied histopathologically.
  • MAIN OUTCOME MEASURES: Clinical evaluation and correlation of clinical findings with histopathologic results of the enucleated eye.
  • The final diagnosis was adenocarcinoma arising from CHRPE.
  • [MeSH-major] Adenocarcinoma / pathology. Cell Transformation, Neoplastic / pathology. Retinal Neoplasms / pathology. Retinal Pigment Epithelium / pathology
  • [MeSH-minor] Eye Enucleation. Female. Humans. Hypertrophy / congenital. Middle Aged. Retinal Detachment / pathology. Retinal Detachment / ultrasonography

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  • (PMID = 19744732.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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59. Saeed MU, Chang BY, Anand S, Chakrabarty A: Diagnostic surprise in an evisceration specimen. Orbit; 2007 Jun;26(2):129-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIMS AND PURPOSE: To report a rare ocular tumor discovered incidentally after evisceration of a painful blind eye.
  • RESULTS: A 67-year-old Caucasian lady presented for elective evisceration of chronically irritable phthisical right eye.
  • A history of bilateral retinal detachment surgery 34 years prior followed by phthisis of the right eye was noted.
  • This was reported as a primary adenocarcinoma of the retinal pigment epithelium after expert histological opinion.
  • The possibilities of a secondary adenocarcinoma with possible primary sites as lung, breast or kidney were ruled out by immuno-histochemical techniques.
  • CONCLUSION: In the absence of a recognizable source of metastasis, a diagnosis of primary ocular adenocarcinoma has been made with retinal pigment epithelium being the possible site of origin.
  • Literature review shows that primary ocular adenocarcinoma arising from neuroepithelium is a rare but recognized occurrence especially in longstanding blind eyes.
  • [MeSH-major] Adenocarcinoma / diagnosis. Eye Evisceration. Retinal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Incidental Findings

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  • (PMID = 17613862.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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60. Palamar M, Shields CL, Marr BP, Eagle RC Jr, Shields JA: Retinal pigment epithelial tumor in a young Asian female. Eur J Ophthalmol; 2009 May-Jun;19(3):487-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: To report a case of low-grade adenocarcinoma of the retinal pigment epithelium (RPE) in a young Asian woman.
  • RESULTS: A 28-year-old Asian woman with a year-long history of floaters presented with a dark pigmented lesion in the right eye.
  • Partial lamellar sclerouvectomy was performed and histopathology revealed a retina pigment epithelial neoplasm consistent with a low-grade adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Retinal Neoplasms / pathology. Retinal Pigment Epithelium / pathology

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  • (PMID = 19396802.001).
  • [ISSN] 1120-6721
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
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61. Zeng J, Shi JT, Li B, Sun XL, An YZ, Li LQ, Gao F, Xu JP, Jonas JB: Epithelial tumors of the lacrimal gland in the Chinese: a clinicopathologic study of 298 patients. Graefes Arch Clin Exp Ophthalmol; 2010 Sep;248(9):1345-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Pleomorphic adenomas were the most common tumors (n = 213 (72%)), followed by adenoid cystic carcinoma (n = 58 (20%)), pleomorphic adenocarcinoma (n = 13 (4%)), primary adenocarcinoma (n = 8 (3%)) and other tumors (n = 6 (2%)).
  • The most frequent symptoms and clinical signs were restrictions of the lid or eye motility (121 patients; 41%), any other kind of lid involvement (71 patients; 24%), swelling (57 patients; 19%), pain (57 patients; 8%), and decrease in vision (15 patients; 5%).
  • A restriction of the eye motility was noted for 61 patients (21%), due to an involvement of the extraocular muscles with the tumor and due to a tumor-induced displacement of the globe.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Pleomorphic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology

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  • (PMID = 20354863.001).
  • [ISSN] 1435-702X
  • [Journal-full-title] Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
  • [ISO-abbreviation] Graefes Arch. Clin. Exp. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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62. Muzumdar DP, Goel A, Fattepurkar S, Goel N: Endolymphatic sac carcinoma of the right petrous bone in Von Hippel-Lindau disease. J Clin Neurosci; 2006 May;13(4):471-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A large endolymphatic sac papillary adenocarcinoma in a patient with Von Hippel-Lindau (vHL) disease is reported.
  • A 31-year-old man was treated for a left eye retinal angioma 10 years previously and had been blind in that eye since.
  • [MeSH-major] Adenocarcinoma, Papillary / complications. Endolymphatic Sac / pathology. Petrous Bone / pathology. Skull Neoplasms / complications. von Hippel-Lindau Disease / complications

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  • (PMID = 16678727.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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63. Bindra M, Keegan DJ, Guenther T, Lee V: Primary cutaneous mucinous carcinoma of the eyelid in a young male. Orbit; 2005 Sep;24(3):211-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Primary cutaneous mucinous carcinoma of the eyelid is an adenocarcinoma of the eccrine glands.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / surgery. Eyelid Neoplasms / pathology. Eyelid Neoplasms / surgery
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Mohs Surgery

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  • (PMID = 16169809.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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64. Henson DE, Schwartz AM, Tilara A, Grimley PM, Anderson WF: Population-based analysis of pathologic data: a new approach to the investigation of uterine endometrial and ovarian endometrioid carcinomas. Arch Pathol Lab Med; 2007 Sep;131(9):1337-42
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  • CONTEXT: Population-based analysis of the histopathology of endometrioid adenocarcinoma of the endometrium and ovary combined with epidemiologic techniques offer a new approach to exploring the relationship of tumors that share a similar range of morphologic phenotypes.
  • [MeSH-major] Adenocarcinoma / pathology. Endometrial Neoplasms / pathology. Ovarian Neoplasms / pathology. SEER Program. Uterine Neoplasms / pathology

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  • (PMID = 17824787.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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65. Hase R, Miyamoto M, Uehara H, Kadoya M, Ebihara Y, Murakami Y, Takahashi R, Mega S, Li L, Shichinohe T, Kawarada Y, Kondo S: Pigment epithelium-derived factor gene therapy inhibits human pancreatic cancer in mice. Clin Cancer Res; 2005 Dec 15;11(24 Pt 1):8737-44
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  • PURPOSE: Pigment epithelium-derived factor (PEDF), which has recently been shown to be the most potent inhibitor of angiogenesis in the mammalian eye, is also expressed in the pancreas.
  • EXPERIMENTAL DESIGN: We investigated both in vitro and in vivo growth characteristics of human pancreatic adenocarcinoma cell lines that were stably transfected to overexpress human PEDF and therapeutic effects of lentivirus-based vectors expressing PEDF on tumor growth in murine s.c. tumor model.
  • The size of PEDF-overexpressing pancreatic adenocarcinoma tumors was significantly smaller than that of control tumors in s.c. tumor models.
  • Moreover, the growth of PEDF-overexpressing pancreatic adenocarcinoma cells was significantly suppressed in comparison with control cells in peritoneal metastasis models.
  • CONCLUSION: Our data suggest that PEDF may exert a biological effect on tumor angiogenesis and PEDF gene therapy may provide a new approach for treatment of pancreatic adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / therapy. Eye Proteins / genetics. Genetic Therapy. Neovascularization, Pathologic / therapy. Nerve Growth Factors / genetics. Pancreatic Neoplasms / therapy. Serpins / genetics

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  • (PMID = 16361561.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Eye Proteins; 0 / Nerve Growth Factors; 0 / RNA, Messenger; 0 / Serpins; 0 / pigment epithelium-derived factor
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66. Bi YW, Chen RJ, Li XP: [Clinical and pathological analysis of primary lacrimal sac tumors]. Zhonghua Yan Ke Za Zhi; 2007 Jun;43(6):499-504
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  • All epithelial lacrimal sac tumors (83 cases, 86.5%) were malignant and squamous cell carcinoma was the most common tumor (64 cases, 66.7%), followed by undifferentiated carcinoma (10 cases, 10.4%), mucoepidermoid carcinoma (4 cases, 4.2%), adenocarcinoma (4 cases, 4.2%) and transitional cell carcinoma (1 case, 1.0%).
  • Therefore, ophthalmologists should pay more attention to the diagnosis of lacrimal sac tumors.
  • [MeSH-major] Eye Neoplasms / pathology. Lacrimal Apparatus / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Mucoepidermoid / pathology. Carcinoma, Squamous Cell / pathology. Child. Female. Humans. Lymphoma, B-Cell, Marginal Zone / pathology. Male. Middle Aged. Retrospective Studies

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  • (PMID = 17897525.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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67. Nitta Y, Yoshida K, Nakagata N, Nitta K, Harada T, Ishizaki F: Intestinal tumorigenicity of mice carrying hemizygous Pax6, Pax6(Sey-4H). Exp Anim; 2007 Jul;56(4):289-94
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  • The genotype-phenotype relationship in mice was examined experimentally using one of the small eye mutants, Pax6(Sey-4H), which deletes the chromosome 2 middle region, hemizygously.
  • Considering the results of the Pax6(Sey-4H) mutant together with those of another small eye mutant, Pax6(Sey-3H), the anomaly and the tumorigenicity of the intestinal tract were closely related to the hemizygosity of the 3.2 Mb segment of chromosome 2, where both mutants show a common deletion.

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  • (PMID = 17660683.001).
  • [ISSN] 1341-1357
  • [Journal-full-title] Experimental animals
  • [ISO-abbreviation] Exp. Anim.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Eye Proteins; 0 / Homeodomain Proteins; 0 / PAX6 protein; 0 / Paired Box Transcription Factors; 0 / Repressor Proteins
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68. Kaushik S, Gupta V, Singh R, Vasishta RK, Rajwanshi A, Gupta A: Disseminated metastasis following periampullary cancer resection masquerading as uveitis. Indian J Ophthalmol; 2005 Mar;53(1):57-9
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  • We report a patient with disseminated malignancy who presented with uveitis 5 years after an apparently successful resection of periampullary adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Ampulla of Vater. Common Bile Duct Neoplasms / pathology. Eye Neoplasms / diagnosis. Eye Neoplasms / secondary. Uveitis / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Tomography, X-Ray Computed. Vitrectomy. Vitreous Body / pathology

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  • (PMID = 15829749.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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69. Miyahara H, Itou H, Sekine A, Taniyama D, Katsui T, Tanaka W, Satou R, Kurihara A, Satou Y, Sakamaki F: [A case of adult T-cell leukemia/lymphoma with primary lung cancer]. Nihon Kokyuki Gakkai Zasshi; 2009 Apr;47(4):342-6
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  • CASE: A 55-year-old man attended our hospital because of a mass at the above his right eye.
  • Furthermore, since we noted multiple cervical lymphadenopathy, we performed an additional biopsy, which showed poorly-differentiated adenocarcinoma.
  • There was invasion of ATLL in systemic lymph nodes, which coincided with invasion of adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Leukemia-Lymphoma, Adult T-Cell / pathology. Lung Neoplasms / pathology. Neoplasms, Multiple Primary

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  • (PMID = 19455967.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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70. Hajda M, Korányi K, Salomváry B, Bajcsay A: [Clinical presentation, differential diagnosis and treatment of lacrimal gland tumours]. Magy Onkol; 2005;49(1):65-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical presentation, differential diagnosis and treatment of lacrimal gland tumours].
  • Epithelial lacrimal gland tumours, which may be benign or malignant (benign pleomorphic adenoma, malignant pleomorphic adenocarcinoma, adenoid cystic carcinoma, other carcinomas).
  • The differential diagnosis and management are based on the clinical presentations, imaging studies and histological examination.
  • The prognosis of pleomorphic adenomas depends on the early diagnosis and radical surgical excision of the lesion.
  • [MeSH-major] Eye Neoplasms / diagnosis. Eye Neoplasms / therapy. Lacrimal Apparatus. Orbital Diseases / diagnosis. Orbital Diseases / therapy
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Adenoma / diagnosis. Adenoma / therapy. Cystadenocarcinoma / diagnosis. Cystadenocarcinoma / therapy. Diagnosis, Differential. Granuloma / diagnosis. Granuloma / therapy. Hodgkin Disease / diagnosis. Hodgkin Disease / therapy. Humans. Leukemia / diagnosis. Leukemia / therapy. Lymphoma / diagnosis. Lymphoma / therapy. Lymphoma, Non-Hodgkin / diagnosis. Lymphoma, Non-Hodgkin / therapy. Orbital Pseudotumor / diagnosis. Orbital Pseudotumor / therapy. Plasmacytoma / diagnosis. Plasmacytoma / therapy. Prognosis. Retrospective Studies. Sarcoidosis / diagnosis. Sarcoidosis / therapy. Treatment Outcome

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  • (PMID = 15902337.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
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71. Walrath JD, Lelli GJ Jr, Engelbert M, Kazim M: Metastatic endometrial carcinoma resulting in orbital apex compression. Ophthal Plast Reconstr Surg; 2007 May-Jun;23(3):250-1
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  • The underlying diagnosis was confirmed with repeat endometrial biopsy, revealing well-differentiated endometrial adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Endometrial Neoplasms / pathology. Nerve Compression Syndromes / etiology. Optic Nerve Diseases / etiology. Orbital Neoplasms / secondary. Paranasal Sinus Diseases / etiology

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  • (PMID = 17519676.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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72. Priyadarshini O, Biswas G, Biswas S, Padhi R, Rath S: Neoadjuvant chemotherapy in recurrent sebaceous carcinoma of eyelid with orbital invasion and regional lymphadenopathy. Ophthal Plast Reconstr Surg; 2010 Sep-Oct;26(5):366-8
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  • A 35-year-old man presented with a recurrent temporal conjunctival mass (25 × 12 mm) involving about six-clock hours of the limbus in the left eye.
  • At thirty-six weeks after treatment the left eye recorded a visual acuity of finger counting at 1 meter distance and no recurrence.
  • [MeSH-major] Adenocarcinoma, Sebaceous / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Eyelid Neoplasms / drug therapy. Neoplasm Recurrence, Local / drug therapy. Orbital Neoplasms / drug therapy. Sebaceous Gland Neoplasms / drug therapy

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  • (PMID = 20856079.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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73. Qi J, Zhu YQ, Luo J, Tao WH, Zhang JM: [Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]. Zhonghua Zhong Liu Za Zhi; 2007 Nov;29(11):842-5
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  • RESULTS: None of the normal colorectal mucosa tissues showed methylation of sFRP genes. sFRP1, 2, 4 and 5 were frequently methylated in colorectal adenocarcinoma, adenoma and aberrant crypt foci (ACF) (sFRP1 > 85%, sFRP2 > 75%, sFRP5 > 50%), the differences between any two of them were not significant (P >0.05).
  • [MeSH-major] Adenocarcinoma / metabolism. Colorectal Neoplasms / metabolism. DNA Methylation. Intercellular Signaling Peptides and Proteins / metabolism. Membrane Proteins / metabolism
  • [MeSH-minor] Adenoma / genetics. Adenoma / metabolism. Adenoma / pathology. Adult. Aged. Azacitidine / analogs & derivatives. Azacitidine / pharmacology. Biomarkers, Tumor. Colonic Neoplasms / genetics. Colonic Neoplasms / metabolism. Colonic Neoplasms / pathology. DNA Modification Methylases / antagonists & inhibitors. Eye Proteins / genetics. Eye Proteins / metabolism. Female. Gene Expression Regulation, Neoplastic. Gene Silencing. HCT116 Cells. Histone Deacetylase Inhibitors / pharmacology. Humans. Hydroxamic Acids / pharmacology. Male. Middle Aged. RNA, Messenger / metabolism

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  • (PMID = 18396643.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Eye Proteins; 0 / Histone Deacetylase Inhibitors; 0 / Hydroxamic Acids; 0 / Intercellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / RNA, Messenger; 0 / SFRP1 protein, human; 0 / SFRP2 protein, human; 0 / SFRP5 protein, human; 3X2S926L3Z / trichostatin A; 776B62CQ27 / decitabine; EC 2.1.1.- / DNA Modification Methylases; M801H13NRU / Azacitidine
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74. DiBernardo CW, Parekh P, Handa JT, Goldberg MF: The suboptimal role of optical coherence tomography in diagnosing choroidal metastasis in the macula. Retin Cases Brief Rep; 2010;4(4):397-400

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • An initial, erroneous diagnosis of a serous pigment epithelial detachment of the macula had been based on ophthalmoscopic and optical coherence tomography findings.
  • METHODS: Case report of a patient with blurred vision in one eye and presumed serous pigment epithelial detachment.
  • His prostate-specific antigen was found to be elevated to 61.4 ng/mL, and a prostate biopsy was positive for adenocarcinoma.

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  • (PMID = 25390929.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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75. Iizuka T, Kikuchi D, Hoteya S, Yahagi N: The acetic acid + indigocarmine method in the delineation of gastric cancer. J Gastroenterol Hepatol; 2008 Sep;23(9):1358-61
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  • BACKGROUND AND AIM: For the purpose of precise preoperative diagnosis that ensures complete endoscopic resection, it is important to accurately determine the lateral spread of gastric cancer lesions.
  • The borderline clarification rate obtained by the AI method and the indigocarmine (I) method were compared between the lesions with and without clear borders under observation with the naked eye.
  • CONCLUSION: The present study stresses that the AI method should be used to conduct ESD more safely and accurately in patients with well or moderately differentiated adenocarcinoma.
  • [MeSH-major] Acetic Acid. Adenocarcinoma / pathology. Coloring Agents. Gastric Mucosa / pathology. Gastroscopy. Indigo Carmine. Stomach Neoplasms / pathology

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  • (PMID = 18853994.001).
  • [ISSN] 1440-1746
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Coloring Agents; D3741U8K7L / Indigo Carmine; Q40Q9N063P / Acetic Acid
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76. Kaya A, Oner F, Fitöz S, Erden I, Numanoğlu N: Metastatic lung cancer: presenting with ocular symptoms. Tuberk Toraks; 2005;53(4):386-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 48 year-old man, without any systemic disease, was admitted to our hospital with a complaint of decreased visual acuity and pain in his left eye.
  • [MeSH-major] Adenocarcinoma / secondary. Carcinoma, Bronchogenic / pathology. Eye Neoplasms / secondary. Lung Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 16456738.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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77. Benhaddou R, Sayouti A, Khoumiri R, Guelzim H, Gaboune L, Benfdil N, Moutaouakil A, Benhaddou A, Essadki O, Ousehal A: [Iris metastasis from lung cancer]. J Fr Ophtalmol; 2008 Apr;31(4):427-9
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  • A 47-year-old man with a history of lung adenocarcinoma presented a red and painful right eye with loss of visual acuity after the 5th course of chemotherapy.
  • The ophthalmologic exam showed visual acuity at 3/10 and diffuse iris nodular lesions in the same eye.
  • The controlateral eye was normal.
  • [MeSH-major] Adenocarcinoma / secondary. Iris Neoplasms / secondary. Lung Neoplasms / pathology

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  • (PMID = 18563045.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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78. Xu XL, Li B, Sun XL, Li LQ, Ren RJ, Gao F: [Clinical and pathological analysis of 2639 cases of eyelid tumors]. Zhonghua Yan Ke Za Zhi; 2008 Jan;44(1):38-41
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  • The mean age at diagnosis was 61 years for basal cell carcinoma and sebaceous gland carcinoma, 57 years and 52 years for squamous cell carcinoma and melanoma, respectively, and 48 years for lymphoma.
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Carcinoma, Basal Cell / pathology. Eyelid Neoplasms / pathology. Lymphoma / pathology

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  • (PMID = 18510241.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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79. Shields JA, Shields CL, Marr BP, Eagle RC Jr: Sebaceous carcinoma of the caruncle. Cornea; 2006 Aug;25(7):858-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Eyelid Neoplasms / pathology. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans

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  • (PMID = 17068467.001).
  • [ISSN] 0277-3740
  • [Journal-full-title] Cornea
  • [ISO-abbreviation] Cornea
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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80. Bandyopadhyay S, Adrean SD, Puklin JE, Feng J: Choroidal metastasis from an occult primary diagnosed by fine-needle aspiration: a case report. Diagn Cytopathol; 2009 Jan;37(1):38-41
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  • We described fine needle aspiration biopsy (FNAB) of a choroidal mass for diagnosis and determining the primary site.
  • The diagnosis of metastatic adenocarcinoma was rendered.
  • [MeSH-major] Adenocarcinoma / secondary. Choroid Neoplasms / secondary. Eye / pathology. Lung Neoplasms / pathology

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18973116.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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81. Besirli CG, Comer GM: High-resolution OCT imaging of RPE degeneration in bilateral diffuse uveal melanocytic proliferation. Ophthalmic Surg Lasers Imaging; 2010 Nov-Dec;41 Suppl:S96-S100

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Bilateral diffuse uveal melanocytic proliferation was diagnosed based on these clinical findings, and a systemic evaluation for malignancy revealed metastatic endometrial adenocarcinoma.
  • These imaging modalities can contribute to the rapid and accurate diagnosis of bilateral diffuse uveal melanocytic proliferation.
  • [MeSH-major] Melanocytes / pathology. Paraneoplastic Syndromes / diagnosis. Retinal Degeneration / diagnosis. Retinal Pigment Epithelium / pathology. Tomography, Optical Coherence. Uveal Diseases / diagnosis
  • [MeSH-minor] Adenocarcinoma / radiography. Adenocarcinoma / secondary. Aged. Biopsy, Needle. Endometrial Neoplasms / pathology. Endometrial Neoplasms / radiography. Female. Fluorescein Angiography. Functional Laterality. Humans. Lymphatic Metastasis. Lymphography. Subretinal Fluid. Visual Acuity

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 21117612.001).
  • [ISSN] 1938-2375
  • [Journal-full-title] Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
  • [ISO-abbreviation] Ophthalmic Surg Lasers Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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82. Alsuhaibani AH, Carter KD, Nerad JA, Lee AG: Prostate carcinoma metastasis to extraocular muscles. Ophthal Plast Reconstr Surg; 2008 May-Jun;24(3):233-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Orbital involvement is uncommon and extraocular muscle enlargement is a rare presentation of metastatic prostate adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Eye Neoplasms / secondary. Muscle Neoplasms / secondary. Oculomotor Muscles / pathology. Prostatic Neoplasms / pathology

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  • (PMID = 18520846.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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83. Oneç B, Oksüzoğlu B, Hatipoğlu HG, Oneç K, Azak A, Zengin N: Cavernous sinus syndrome caused by metastatic colon carcinoma. Clin Colorectal Cancer; 2007 Jul;6(8):593-6
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  • A 34-year-old man underwent a right hemicolectomy for a mucinous adenocarcinoma of the right colon 14 months before presentation.
  • After 5 months of the last cycle of the chemotherapy, his left eyelid began to droop, left eye movements became limited, and he began experiencing numbness of his right forehead and cheek.
  • Primary colon adenocarcinoma with cavernous sinus metastasis is very rare.
  • [MeSH-major] Adenocarcinoma / secondary. Brain Neoplasms / secondary. Cavernous Sinus. Colonic Neoplasms / pathology

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  • (PMID = 17681107.001).
  • [ISSN] 1533-0028
  • [Journal-full-title] Clinical colorectal cancer
  • [ISO-abbreviation] Clin Colorectal Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Moura LR, Ayres B, Feijóo L, Romano S, Odashiro AN, Burnier MN Jr: Presumed eccrine carcinoma metastatic to the choroid. Clin Exp Ophthalmol; 2006 Sep-Oct;34(7):699-700
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  • The purpose of this article is to describe a patient with presumed choroidal metastasis from an eccrine adenocarcinoma of the scalp.
  • Multiple choroidal metastases were detected in right eye, and one metastatic lesion in left eye.
  • [MeSH-major] Adenocarcinoma / secondary. Choroid Neoplasms / secondary. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 16970766.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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85. Li Y, Zhang TM, An YZ, Shi JT, Fu JD, Qiu E: [Clinical study of lacrimal gland tumor involving anterior and middle cranial fossae]. Zhonghua Yi Xue Za Zhi; 2006 Jun 20;86(23):1597-9
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  • METHODS: A retrospective study was conducted on the clinical data of 23 cases lacrimal gland tumor involving the anterior and middle cranial fossae confirmed by radiological examination, including 11 cases of adenoid cystic carcinoma, 6 cases of pleomorphic adenocarcinoma (malignant mixed tumor), 2 cases of adenocarcinoma, 1 case of squamous cell carcinoma, 1 case of ductal carcinoma, 1 case of mucoepidermoid carcinoma, and 1 case of benign mixed tumor, 15 males and 8 females, aged 42.5 (2 - 76), with a case history of 43 months (2 months to 27 years), with the chief complaints of progressive proptosis, disgenesia of the eye ball, and orbit pain, all undergoing transcranial-orbital operation from August 1998 to February. 2006.
  • Recurrence of tumor occurred in 4 cases, and 1 case died from distant metastasis of adenocarcinoma.
  • [MeSH-major] Eye Neoplasms / pathology. Lacrimal Apparatus / pathology. Skull Base Neoplasms / pathology

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  • (PMID = 16854296.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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86. Kocabora MS, Durmaz S, Bilgic L: Bilateral choroidal metastases presenting as acute glaucoma crisis. Ann Ophthalmol (Skokie); 2008 Fall-Winter;40(3-4):163-5
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  • A painful and hypertensive eye could be symptoms of choroidal metastasis even if no systemic malignancy is encountered.
  • [MeSH-major] Adenocarcinoma, Papillary / secondary. Choroid Neoplasms / secondary. Glaucoma, Neovascular / diagnosis. Lung Neoplasms / pathology
  • [MeSH-minor] Acute Disease. Biomarkers, Tumor / analysis. Eye Enucleation. Female. Functional Laterality. Humans. Middle Aged

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  • (PMID = 19230354.001).
  • [ISSN] 1530-4086
  • [Journal-full-title] Annals of ophthalmology (Skokie, Ill.)
  • [ISO-abbreviation] Ann Ophthalmol (Skokie)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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87. Assheton DC, Guerin EP, Sheridan CM, Bishop PN, Hiscott PS: Neoplastic transformation of ciliary body epithelium is associated with loss of opticin expression. Br J Ophthalmol; 2007 Feb;91(2):230-2
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  • By contrast, none of eight neoplastic lesions (two adenoma and six adenocarcinoma) of CBE stained for opticin.
  • [MeSH-major] Cell Transformation, Neoplastic / metabolism. Ciliary Body / metabolism. Extracellular Matrix Proteins / metabolism. Eye Proteins / metabolism. Proteoglycans / metabolism. Uveal Neoplasms / metabolism
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenoma / metabolism. Adolescent. Adult. Aged. Aged, 80 and over. Child. Disease Progression. Female. Humans. Hyperplasia / metabolism. Immunoenzyme Techniques. Male. Middle Aged. Pigment Epithelium of Eye / metabolism. Precancerous Conditions / metabolism. Retrospective Studies

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  • (PMID = 17005546.001).
  • [ISSN] 0007-1161
  • [Journal-full-title] The British journal of ophthalmology
  • [ISO-abbreviation] Br J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Extracellular Matrix Proteins; 0 / Eye Proteins; 0 / OPTC protein, human; 0 / Proteoglycans
  • [Other-IDs] NLM/ PMC1857628
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88. Moore MG, Deschler DG, McKenna MJ, Varvares MA, Lin DT: Management outcomes following lateral temporal bone resection for ear and temporal bone malignancies. Otolaryngol Head Neck Surg; 2007 Dec;137(6):893-8
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  • RESULTS: In this group of 35 patients, the mean age was 62.7 years, with tumor histopathologies including squamous cell carcinoma (SCC, 20), basal cell carcinoma (BCC, 7), adenoid cystic carcinoma (ACC, 7), and adenocarcinoma (1).
  • [MeSH-minor] Adenocarcinoma / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Disease-Free Survival. Ear Canal / surgery. Ear, External / surgery. Ear, Middle / surgery. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Parotid Gland / surgery. Retrospective Studies. Survival Rate. Treatment Outcome

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  • (PMID = 18036417.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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89. Sen J, Clewes AR, Quah SA, Hiscott PS, Bucknall RC, Damato BE: Presymptomatic diagnosis of bronchogenic carcinoma associated with bilateral diffuse uveal melanocytic proliferation. Clin Exp Ophthalmol; 2006 Mar;34(2):156-8
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  • [Title] Presymptomatic diagnosis of bronchogenic carcinoma associated with bilateral diffuse uveal melanocytic proliferation.
  • The diagnosis was confirmed by trans-scleral biopsy of the right choroid.
  • Severe exudative retinal detachment with rubeosis and neovascular glaucoma in the left eye were treated successfully by partial choroidectomy.
  • Fifteen months after presentation, investigations detected a 22 mm, poorly differentiated adenocarcinoma, which was resected without complication.
  • [MeSH-major] Carcinoma, Bronchogenic / diagnosis. Choroid Diseases / pathology. Lung Neoplasms / diagnosis. Melanocytes / pathology. Paraneoplastic Syndromes / pathology

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  • (PMID = 16626431.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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90. Wang GL, Wang MY, Wei WB: [Clinical features and treatment of choroidal metastasis]. Zhonghua Yan Ke Za Zhi; 2009 Mar;45(3):229-33

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Transpupillary thermotherapy (TTT) was performed in 24 eyes, combined with photo-dynamic therapy in one eye.
  • Plaque radio-therapy was used in one eye.
  • Primary tumours were found in 40 cases (81.6%) (surgical excision in 25 cases), consisting of breast carcinoma in 16 cases (32.7%), lung carcinoma in 14 cases (28.6%), hepatoma and cholangiocarcinoma in 3 cases, colon and stomach carcinomas in 3 cases, gynecologic appendix carcinoma (including 1 case of ovarian mucous cyst adenocarcinoma) in 2 cases, nasopharyngeal adenocarcinoma in 1 case, vertebra tumor in 1 case, undetected in 5 cases (10.2%) and under detection in 4 cases (8.2%).
  • The fundus had 1 lesion in 58 eyes (58/66 = 87.8%), 2 lesions in 4 eyes (4/66 = 6.0%), 3 or more lesions in 2 eyes (including 7 lesions in 1 eye).

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  • (PMID = 19575917.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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91. Singh RP, Tullis S, Hatton M, Rubin PA: Orbital metastasis from ovarian carcinoma in a patient with BRCA-2 mutation. Ophthal Plast Reconstr Surg; 2006 Jul-Aug;22(4):298-9
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  • A 45-year-old woman with BRCA-2 mutation-positive ovarian carcinoma had pain, swelling, and proptosis of her left eye.
  • Fine-needle aspiration and lateral orbitotomy were used to obtain tissue for diagnosis.
  • [MeSH-major] Adenocarcinoma / secondary. Genes, BRCA2. Mutation / genetics. Orbital Neoplasms / secondary. Ovarian Neoplasms / genetics. Ovarian Neoplasms / pathology

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  • (PMID = 16855505.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Wang TJ, Chen MS, Yang CM, Ho TC: Subthreshold transpupillary thermotherapy for early resolution of foveal subretinal fluid in choroidal metastasis. Retina; 2006 Apr;26(4):391-5
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  • METHODS: : Three consecutive patients who had adenocarcinoma of the lung with choroidal metastasis and macular subretinal fluid were treated by subthreshold TTT.
  • Best-corrected visual acuity in Patient 2, a 68-year-old woman, was 10/200 in the right eye before treatment.
  • [MeSH-major] Adenocarcinoma / therapy. Choroid Neoplasms / therapy. Hyperthermia, Induced / methods. Lung Neoplasms / pathology. Pupil

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  • (PMID = 16603956.001).
  • [ISSN] 0275-004X
  • [Journal-full-title] Retina (Philadelphia, Pa.)
  • [ISO-abbreviation] Retina (Philadelphia, Pa.)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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93. Duthoy W, Boterberg T, Claus F, Ost P, Vakaet L, Bral S, Duprez F, Van Landuyt M, Vermeersch H, De Neve W: Postoperative intensity-modulated radiotherapy in sinonasal carcinoma: clinical results in 39 patients. Cancer; 2005 Jul 1;104(1):71-82
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  • METHODS: Between 1998 and 2003, 39 consecutive patients received postoperative irradiation by means of IMRT for an adenocarcinoma (n = 31) or squamous cell carcinoma (n = 8) of the paranasal sinuses (n = 36) or nasal cavity (n = 3).
  • [MeSH-major] Adenocarcinoma / radiotherapy. Carcinoma, Squamous Cell / radiotherapy. Paranasal Sinus Neoplasms / radiotherapy. Radiotherapy, Adjuvant / methods
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Ethmoid Sinus. Eye Injuries / etiology. Humans. Middle Aged. Postoperative Period. Radiotherapy Dosage. Survival Analysis. Vision, Low / etiology

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  • (PMID = 15915466.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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94. Klosterman E, Colitz CM, Chandler HL, Kusewitt DF, Saville WJ, Dubielzig RR: Immunohistochemical properties of ocular adenomas, adenocarcinomas and medulloepitheliomas. Vet Ophthalmol; 2006 Nov-Dec;9(6):387-94
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  • Therefore, this study focused on identifying a combination of immunologic markers that might be used in the diagnosis of these tumors.
  • [MeSH-major] Antibodies. Biomarkers, Tumor / immunology. Dog Diseases / diagnosis. Dog Diseases / immunology. Eye Neoplasms / veterinary
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / immunology. Adenocarcinoma / veterinary. Adenoma / diagnosis. Adenoma / immunology. Adenoma / veterinary. Animals. Dogs. Female. Immunohistochemistry / veterinary. Male. Neuroectodermal Tumors, Primitive / diagnosis. Neuroectodermal Tumors, Primitive / immunology. Neuroectodermal Tumors, Primitive / veterinary. Predictive Value of Tests

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  • (PMID = 17076871.001).
  • [ISSN] 1463-5216
  • [Journal-full-title] Veterinary ophthalmology
  • [ISO-abbreviation] Vet Ophthalmol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies; 0 / Biomarkers, Tumor
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95. Roshdy N, Shahin M, Kishk H, Ghanem AA, El-Khouly S, Mousa A, Elsalekh I: MRI in diagnosis of orbital masses. Curr Eye Res; 2010 Nov;35(11):986-91
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  • [Title] MRI in diagnosis of orbital masses.
  • PURPOSE: To evaluate the role of diffusion-weighted magnetic resonance imaging and proton magnetic resonance spectroscopy in diagnosis of different orbital masses and their advantages over conventional magnetic resonance imaging.
  • CONCLUSION: Diffusion-weighted MRI and proton magnetic resonance spectroscopy increased the accuracy of diagnosis of orbital masses through giving in vivo tissue characterization; with magnetic resonance spectroscopy being more accurate.
  • [MeSH-major] Magnetic Resonance Imaging. Orbital Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adult. Exophthalmos / diagnosis. Eyelid Neoplasms / diagnosis. Female. Humans. Lacrimal Apparatus Diseases / diagnosis. Lymphoma / diagnosis. Male. Meibomian Glands / pathology. Melanoma / diagnosis. Middle Aged. Protons. Rhabdomyosarcoma / diagnosis

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  • (PMID = 20958187.001).
  • [ISSN] 1460-2202
  • [Journal-full-title] Current eye research
  • [ISO-abbreviation] Curr. Eye Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Protons
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96. Biswas J, Ho TC, Bhavsar K: Bilateral metastasis to the retina, choroids and optic nerve from breast cancer: a clinicopathological case. Indian J Ophthalmol; 2007 Jan-Feb;55(1):71-2
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  • Examination revealed visual acuity of counting fingers in the right eye and light perception in the left.
  • There were subretinal lesions in the posterior poles of both eyes and retinal detachment in the left eye.
  • The tumor cells were arranged in lobular fashion and stained positively with Periodic Acid Schiff, suggesting the primary to be lobular adenocarcinoma type.

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  • (PMID = 17189895.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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97. Chang CJ, Lin TK, Wei LC, Wen MC, Tsai HY, Wang JC, Tai MC: Carcinoma ex pleomorphic adenoma of the lacrimal gland: a case report. Ann Ophthalmol (Skokie); 2006;38(2):141-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma, Pleomorphic / diagnosis. Eye Neoplasms / diagnosis. Lacrimal Apparatus Diseases / diagnosis

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  • (PMID = 17416946.001).
  • [ISSN] 1558-9951
  • [Journal-full-title] Annals of ophthalmology (Skokie, Ill.)
  • [ISO-abbreviation] Ann Ophthalmol (Skokie)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Rootman J, White VA: Changes in the 7th edition of the AJCC TNM classification and recommendations for pathologic analysis of lacrimal gland tumors. Arch Pathol Lab Med; 2009 Aug;133(8):1268-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Eye Neoplasms / diagnosis. Lacrimal Apparatus / pathology. Neoplasm Staging / methods

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  • (PMID = 19653723.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Ivanova MM, Mazhawidza W, Dougherty SM, Minna JD, Klinge CM: Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Mol Cell Endocrinol; 2009 Jun 16;305(1-2):12-21
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  • We reported estrogenic transcriptional responses in lung adenocarcinoma cells from females but not males despite similar estrogen receptor (ER) expression.
  • In contrast to lung adenocarcinoma cells, estradiol (E2) induced estrogen response element (ERE)-mediated luciferase reporter activity in transiently transfected HBECs regardless of donor gender.

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  • (PMID = 19433257.001).
  • [ISSN] 1872-8057
  • [Journal-full-title] Molecular and cellular endocrinology
  • [ISO-abbreviation] Mol. Cell. Endocrinol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA070907-12; United States / NCI NIH HHS / CA / CA070907-12; United States / NCI NIH HHS / CA / P50CA70907; None / None / / P50 CA070907-11; None / None / / P50 CA070907-10; United States / NCI NIH HHS / CA / P50 CA070907-11; United States / NCI NIH HHS / CA / P50 CA070907; United States / NCI NIH HHS / CA / P50 CA070907-10
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Estrogen Receptor alpha; 0 / Estrogen Receptor beta; 0 / Hydroxytestosterones; 2141-17-5 / 4,17 beta-dihydroxy-4-androstene-3-one; 4TI98Z838E / Estradiol
  • [Other-IDs] NLM/ NIHMS148501; NLM/ PMC2767333
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100. Chen RJ, Xiao YQ: [Clinical and pathological analysis of 2734 cases of eyelid neoplasms]. Zhonghua Yan Ke Za Zhi; 2008 Feb;44(2):143-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSION: Pathologic classification of eyelid neoplasms is helpful for the pathological diagnosis and provides information for the diagnosis and treatment of these diseases.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Basal Cell / pathology. Eyelid Neoplasms / pathology

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  • (PMID = 18683700.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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