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Items 1 to 100 of about 303
1. Lee CC, Ng WK, Lin KW, Lai TW, Li SM: Adenocarcinoma of the duodenum. Hong Kong Med J; 2008 Feb;14(1):67-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of the duodenum.
  • Adenocarcinoma of the duodenum is an exceedingly rare disorder.

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  • (PMID = 18239248.001).
  • [ISSN] 1024-2708
  • [Journal-full-title] Hong Kong medical journal = Xianggang yi xue za zhi
  • [ISO-abbreviation] Hong Kong Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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2. Anastasopoulos G, Marinis A, Konstantinidis C, Theodosopoulos T, Fragulidis G, Vassiliou I: Adenocarcinoma of the third portion of the duodenum in a man with CREST syndrome. World J Surg Oncol; 2008;6:106
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  • [Title] Adenocarcinoma of the third portion of the duodenum in a man with CREST syndrome.
  • This is the first report of a primary adenocarcinoma of the third portion of the duodenum in a patient with CREST syndrome.
  • An ulcerative lesion in the third portion of the duodenum was revealed during duodenoscopy, with a diagnosis of adenocarcinoma on biopsy specimen histology.
  • CONCLUSION: CREST syndrome has been associated with colon cancer, gastric polyps, familial adenomatous polyposis (FAP) syndrome and Crohn's disease; however, this is the first report of a primary adenocarcinoma of the duodenum in a patient with CREST syndrome.
  • [MeSH-major] Adenocarcinoma / complications. CREST Syndrome / complications. Duodenal Neoplasms / complications

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  • (PMID = 18828905.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2566573
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3. Ramia JM, Villar J, Palomeque A, Muffak K, Mansilla A, Garrote D, Ferrón JA: [Duodenal adenocarcinoma]. Cir Esp; 2005 Apr;77(4):208-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Duodenal adenocarcinoma].
  • [Transliterated title] Adenocarcinoma de duodeno.
  • INTRODUCTION: Duodenal adenocarcinoma is an infrequent neoplasm.
  • Consequently, there are no large series that would allow conclusions to be reached on its diagnosis and treatment.
  • PATIENTS AND METHOD: A retrospective study (1999-2003) of five patients diagnosed with duodenal adenocarcinoma in our service was performed.
  • All patients underwent gastrointestinal endoscopy with biopsy, which revealed adenocarcinoma.
  • In all patients, the preoperative diagnosis was correct.
  • CONCLUSION: Duodenal adenocarcinoma is an infrequent tumor that is associated with various diseases.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Duodenal Neoplasms / diagnosis. Duodenal Neoplasms / surgery

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  • (PMID = 16420919.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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4. Markogiannakis H, Theodorou D, Toutouzas KG, Gloustianou G, Katsaragakis S, Bramis I: Adenocarcinoma of the third and fourth portion of the duodenum: a case report and review of the literature. Cases J; 2008;1(1):98

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of the third and fourth portion of the duodenum: a case report and review of the literature.
  • Esophagogastroduodenoscopy, until the second part of duodenum, was normal.
  • Ultrasound and computed tomography demonstrated a solid mass in the distal duodenum.
  • A repeat endoscopy confirmed an ulcerative, intraluminar mass in the third and fourth part of the duodenum.
  • Segmental resection of the third and fourth portion of the duodenum was performed.
  • Histology revealed an adenocarcinoma.

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  • (PMID = 18706123.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2527500
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5. Jurisić D, Doko M, Glavan E, Rosko D, Vidović D, Tomić K: Local recurrence of primary non-ampullary adenocarcinoma of duodenum after surgical treatment--a case report and a literature review. Coll Antropol; 2006 Mar;30(1):225-9
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  • [Title] Local recurrence of primary non-ampullary adenocarcinoma of duodenum after surgical treatment--a case report and a literature review.
  • Worldwide there is no general attitude on optimal surgical procedure in treatment of primary non-ampullary adenocarcinoma of duodenum, especially for early stage of duodenal cancer.
  • Some authors prefer local excision and segmental resection while others rather perform duodenopancreatic resection, even in the case of early stage of duodenal cancer with aim to avoid tumor recurrence.
  • In this paper we present a rare clinical course of a 60-year-old male patient with an endoscopically and pathohistologically proven early stage duodenal cancer that was treated by wide local excision.
  • Three years after operation, control endoscopy showed "flat" polyp in the duodenum and radical duodenopancreatic resection was performed.
  • Pathohistological examination of resected specimen showed cancer that had spread throughout the duodenal wall with metastases in the regional lymph nodes.
  • [MeSH-major] Duodenal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 16617602.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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6. Lin YH, Chen CY, Chen CP, Kuo TY, Chang FY, Lee SD: Hematemesis as the initial complication of pancreatic adenocarcinoma directly invading the duodenum: a case report. World J Gastroenterol; 2005 Feb 7;11(5):767-9
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  • [Title] Hematemesis as the initial complication of pancreatic adenocarcinoma directly invading the duodenum: a case report.
  • It is a rare cause of upper gastrointestinal bleeding, even though pancreas, stomach, duodenum and jejunum are adjacent organs.
  • The incidence of pancreatic adenocarcinoma directly invading the gastrointestinal tract leading to gastrointestinal hemorrhage is very low, and most of them present with melena and hematochezia.
  • Here, we describe one unique case manifesting characteristically severe and unremitting hematemesis as an initial presentation of pancreatic adenocarcinoma.
  • This tumor directly invaded the duodenal mucosa as a bleeding protruding tumor mass.
  • Our MEDLINE search has confirmed that this is the first reported case with an initial manifestation of hematemesis from pancreatic adenocarcinoma in Asians.
  • Pancreatic adenocarcinoma directly invading duodenum complicated by hemorrhage can be a rare cause of hematemesis, and clinicians should be reminded of it while they are making differential diagnosis.
  • [MeSH-major] Adenocarcinoma / complications. Duodenum / pathology. Hematemesis / etiology. Pancreatic Neoplasms / complications
  • [MeSH-minor] Aged. Humans. Male. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • (PMID = 15655842.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4250759
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7. Aparajita R, Gomez D, Verbeke CS, Menon KV: Papillary adenoma of the distal common bile duct associated with a synchronous carcinoma of the peri-ampullary duodenum. JOP; 2008;9(2):212-5
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  • [Title] Papillary adenoma of the distal common bile duct associated with a synchronous carcinoma of the peri-ampullary duodenum.
  • The diagnosis of these rare tumours is established on histopathological analysis following resection.
  • Coincidence of a biliary adenoma of the distal common bile duct and a synchronous adenocarcinoma of the peri-ampullary duodenum has never been reported in the literature.
  • CASE REPORT: We report a case of a papillary adenoma in the common bile duct in a 75-year-old female, who had synchronous invasive adenocarcinoma of the peri-ampullary duodenum.
  • CONCLUSION: Isolated papillary adenoma of the bile duct is extremely rare, and in this unusual case it coincided with a peri-ampullary duodenal adenocarcinoma.
  • However, this is a rare instance of an incidental finding within the distal bile duct following pancreaticoduodenectomy for curative treatment of a peri-ampullary adenocarcinoma.
  • [MeSH-major] Adenoma / pathology. Carcinoma / pathology. Common Bile Duct / pathology. Common Bile Duct Neoplasms / pathology. Duodenal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 18326932.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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8. Cienfuegos JA, Baixauli J, Zozaya G, Bueno A, Arredondo J, Regueira FM, Angós R, Hernández-Lizoáin JL, Idoate MA: Peutz-Jeghers syndrome and duodeno-jejunal adenocarcinoma--therapeutic implications. Rev Esp Enferm Dig; 2009 Dec;101(12):875-9
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  • [Title] Peutz-Jeghers syndrome and duodeno-jejunal adenocarcinoma--therapeutic implications.
  • Hemminki in 1997 described the presence of LKB-1 mutation tumor-suppressor gen.The patients with PJS develop a higher cumulative incidence of gastrointestinal, pancreas and extraintestinal tumors, being occasion of a renew interest on hamartomatous polyposis syndromes regarding the clinical care, cancer surveillance treatment and long term follow-up.We report the case of a 38 years old male, diagnosed of PJS who developed a multiple adenocarcinoma in duodenum and yeyunum.
  • [MeSH-major] Adenocarcinoma. Duodenal Neoplasms. Jejunal Neoplasms. Neoplasms, Multiple Primary. Peutz-Jeghers Syndrome / complications
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Disease-Free Survival. Female. Follow-Up Studies. Humans. Infant. Infant, Newborn. Male. Neoplasm Invasiveness / pathology. Pancreaticoduodenectomy. Radiography, Abdominal. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20082550.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Spain
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9. Afridi SP, Mohib Y, Shafiq-ur-Rahman: Primary adenocarcinoma of duodenum. J Coll Physicians Surg Pak; 2010 Feb;20(2):130-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary adenocarcinoma of duodenum.
  • Primary duodenal adenocarcinoma (PDC) of the distal half of duodenum is extremely rare.
  • We report a case of a young male with adenocarcinoma of third and fourth part of duodenum presenting with long standing proximal small bowel obstruction with associated weight loss and anemia.
  • Esophago-gastro-duodeno-scopy showed a fungating intraluminal growth in third and fourth part of the duodenum.
  • Computed tomography also showed a solid mass in the third and fourth part of the duodenum.
  • Computed tomography also showed a solid mass in the third and fourth part of the duodenum.
  • Segmental resection of the third and fourth part of the duodenum was performed with single layer extra mucosal duodenojejunal anastomosis.
  • [MeSH-major] Adenocarcinoma / pathology. Duodenal Neoplasms / pathology

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  • (PMID = 20378043.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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10. Al-Amri A, Al-Quorain AA: Coexisting malignant lymphoma of the duodenum and adenocarcinoma of the colon. Saudi Med J; 2007 Mar;28(3):463-4
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  • [Title] Coexisting malignant lymphoma of the duodenum and adenocarcinoma of the colon.
  • Synchronous malignant mucosa associated lymphoid tissue MALT-lymphoma of the small bowel and adenocarcinoma of the colon in the same patient is a scarce rarity.
  • Thus, it might be of interest to report such a case of coexisting malignant MALT-lymphoma of the duodenum and adenocarcinoma of the large bowel.
  • [MeSH-major] Adenocarcinoma / pathology. Colonic Neoplasms / pathology. Duodenal Neoplasms / pathology. Lymphoma, B-Cell, Marginal Zone / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 17334482.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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11. Bonfante P, Bianchi C, Magistrelli P, Bianco A, D'Ambra L, Berti S, Giaquinto D, Ansaldo V, Falco E: [Primary duodenal adenocarcinoma: report of three cases, prognostic factors and therapeutic approach]. G Chir; 2008 May;29(5):207-11
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  • [Title] [Primary duodenal adenocarcinoma: report of three cases, prognostic factors and therapeutic approach].
  • [Transliterated title] Adenocarcinoma primitivo del duodeno: tre casi clinici e considerazioni prognostico-terapeutiche.
  • Three cases of histologically proven primary non-ampullary adenocarcinoma of the duodenum, observed in our Department from 2001 to 2004, are described.
  • The cases were treated by pancreaticoduodenectomy, duodenal resection and transduodenal excision, respectively.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery

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  • (PMID = 18507955.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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12. Bendixen M, Dahl S, Fristrup C, Mortensen MB: [Evaluation of curative and palliative treatment of duodenal adenocarcinoma]. Ugeskr Laeger; 2010 May 3;172(18):1376-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Evaluation of curative and palliative treatment of duodenal adenocarcinoma].
  • INTRODUCTION: Primary adenocarcinoma of the duodenum is a rare disease in this part of the world, and data on survival following curative and palliative treatment are scarce.
  • MATERIAL AND METHODS: All patients treated for duodenal cancer (DC) at the Department of Surgery, Odense University Hospital, between January 1995 and February 2006 were retrospectively evaluated.
  • Tumours arising from the pancreatic head, the papilla of Vater, distal bile duct or tumour infiltration from surrounding organs (apart from the duodenum) were excluded.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Duodenum / pathology. Female. Humans. Male. Middle Aged. Palliative Care. Retrospective Studies. Survival Rate. Treatment Outcome

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  • (PMID = 20444409.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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13. Kelsey CR, Nelson JW, Willett CG, Chino JP, Clough RW, Bendell JC, Tyler DS, Hurwitz HI, Morse MA, Clary BM, Pappas TN, Czito BG: Duodenal adenocarcinoma: patterns of failure after resection and the role of chemoradiotherapy. Int J Radiat Oncol Biol Phys; 2007 Dec 1;69(5):1436-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Duodenal adenocarcinoma: patterns of failure after resection and the role of chemoradiotherapy.
  • PURPOSE: To report patterns of disease recurrence after resection of adenocarcinoma of the duodenum and compare outcomes between patients undergoing surgery only vs. surgery with concurrent chemotherapy and radiation therapy (CT-RT).
  • METHODS AND MATERIALS: This was a retrospective analysis of all patients undergoing potentially curative therapy for adenocarcinoma of the duodenum at Duke University Medical Center and affiliated hospitals between 1975 and 2005.
  • [MeSH-major] Adenocarcinoma. Duodenal Neoplasms
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy / methods. Disease-Free Survival. Female. Fluorouracil / administration & dosage. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local. Radiotherapy Dosage. Regression Analysis. Retrospective Studies

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  • (PMID = 17689032.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] U3P01618RT / Fluorouracil
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14. Buecher B, Baert-Desurmont S, Leborgne J, Humeau B, Olschwang S, Frébourg T: Duodenal adenocarcinoma and Mut Y human homologue-associated polyposis. Eur J Gastroenterol Hepatol; 2008 Oct;20(10):1024-7
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  • [Title] Duodenal adenocarcinoma and Mut Y human homologue-associated polyposis.
  • Among these, duodenal polyposis, a highly prevalent manifestation of Adenomatous Polyposis Coli related familial adenomatous polypyposis, is undoubtedly part of the clinical spectrum of the disease.
  • The true association of other clinical manifestations with MAP remains questionable.We report the observation of two patients affected by MAP who developed an adenocarcinoma of the duodenum in the context of duodenal polyposis.
  • These observations emphasize the malignant potential of MAP-associated duodenal polyposis and the need to enroll these patients into an upper gastrointestinal surveillance programme.
  • [MeSH-major] Adenocarcinoma / genetics. Adenomatous Polyposis Coli / genetics. Colorectal Neoplasms / genetics. DNA Glycosylases / genetics. Duodenal Neoplasms / genetics. Mutation, Missense

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  • (PMID = 18787472.001).
  • [ISSN] 1473-5687
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] EC 3.2.2.- / DNA Glycosylases; EC 3.2.2.- / mutY adenine glycosylase
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15. Swartz MJ, Hughes MA, Frassica DA, Herman J, Yeo CJ, Riall TS, Lillemoe KD, Cameron JL, Donehower RC, Laheru DA, Hruban RH, Abrams RA: Adjuvant concurrent chemoradiation for node-positive adenocarcinoma of the duodenum. Arch Surg; 2007 Mar;142(3):285-8
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  • [Title] Adjuvant concurrent chemoradiation for node-positive adenocarcinoma of the duodenum.
  • HYPOTHESIS: Adjuvant chemoradiation improves local control and survival in patients with node-positive duodenal adenocarcinoma treated with pancreaticoduodenectomy.
  • Fourteen cases of node-positive duodenal adenocarcinoma were identified.
  • CONCLUSION: Adjuvant chemoradiation therapy after pancreaticoduodenectomy for node-positive duodenal adenocarcinoma may improve local control and median survival but does not impact 5-year overall survival.
  • [MeSH-major] Adenocarcinoma. Antimetabolites, Antineoplastic / therapeutic use. Duodenal Neoplasms. Fluorouracil / therapeutic use

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  • (PMID = 17372054.001).
  • [ISSN] 0004-0010
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; U3P01618RT / Fluorouracil
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16. Lemyé AC, Guy-Viterbo V, van Vyve E: Adenocarcinoma of the duodenum arising in a tubulo-villous adenoma. Acta Chir Belg; 2009 Jan-Feb;109(1):95-7
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  • [Title] Adenocarcinoma of the duodenum arising in a tubulo-villous adenoma.
  • Villous adenoma of the duodenum is rare and has a high prevalence of cancer.
  • We report here an unusual case of a 73-year-old man who presented with a tumour on the second part of the duodenum with moderate dysplasia of a tubulo-villous adenoma at the biopsies.
  • A segmental duodeno-jejunal resection was performed and the resection margins were negative.
  • The final histological analysis was a moderately differentiated invasive duodenal adenocarcinoma (pT3Nx).
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Duodenal Neoplasms / pathology

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  • (PMID = 19341205.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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17. Ruiz-Tovar J, Martínez-Molina E, Morales V, Sanjuanbenito A: [Primary small bowel adenocarcinoma]. Cir Esp; 2009 Jun;85(6):354-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary small bowel adenocarcinoma].
  • [Transliterated title] Adenocarcinoma primario de intestino delgado.
  • INTRODUCTION: Primary small bowel adenocarcinoma is an uncommon tumour, with non-specific symptoms that cause a delay in the diagnosis and consequently a worse outcome for the patient.
  • MATERIAL AND METHOD: We performed a retrospective study of our experience with 17 patients diagnosed with primary small bowel adenocarcinoma, excluding all the cases suggesting secondary involvement of the small bowel from an adenocarcinoma in other locations.
  • Tumour location was duodenum (8 cases), jejunum (5) and ileum (4).
  • Those with duodenal tumours underwent 4 pancreaticoduodenectomies, 3 gastroenterostomies and 1 diagnostic biopsy; 6 bowel resections with lymphadenectomy, 2 en-bloc resections and 1 by-pass were performed on those with jejuno-ileal tumours.
  • General survival was 18 months; in duodenal and jejunal tumours it was 15 months vs. 58 in ileal ones (p = 0.048).
  • CONCLUSIONS: Curative treatment consists of small bowel resection.
  • [MeSH-major] Adenocarcinoma. Duodenal Neoplasms. Ileal Neoplasms. Jejunal Neoplasms

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  • (PMID = 19344893.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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18. Manfredi S, Thiebot T, Henno S, Falize L, Bretagne JF, Meunier B: Complete response of an initially non-surgical adenocarcinoma of the duodenum to chemotherapy with the FOLFOX 4 regimen. J Gastrointest Surg; 2009 Dec;13(12):2309-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Complete response of an initially non-surgical adenocarcinoma of the duodenum to chemotherapy with the FOLFOX 4 regimen.
  • INTRODUCTION: The incidence of adenocarcinoma of the small bowel is very low in comparison with that of colorectal cancer.
  • No standard chemotherapy is defined for non-surgical adenocarcinoma of the small bowel.
  • CASE REPORT: We report here the case of a young patient with an initially non-surgical adenocarcinoma of the duodenum treated in a palliative setting with the FOLFOX 4 chemotherapy regimen.
  • A multidisciplinary committee decided that a second surgical investigation was necessary, and a duodenal resection was performed, with no residual tumor in the final specimen.
  • CONCLUSION: The FOLFOX 4 regimen seems to be efficacious for some small-bowel adenocarcinomas and can be expected to lead to downstaging.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Duodenal Neoplasms / drug therapy

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  • (PMID = 19585173.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Folfox protocol
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19. Bulfoni A: [Primary adenocarcinoma of jejunum with obscure gastrointestinal bleeding]. Clin Ter; 2006 Sep-Oct;157(5):431-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary adenocarcinoma of jejunum with obscure gastrointestinal bleeding].
  • [Transliterated title] Adenocarcinoma primitivo del digiuno ad esteriorizzazione con enterorragia.
  • A case of primary small bowel adenocarcinoma is reported because of the rarity of this malignancy.
  • Interestingly, the location of the tumour was in jejunum, instead of the most common site in duodenum.
  • [MeSH-major] Adenocarcinoma. Gastrointestinal Hemorrhage / etiology. Jejunal Neoplasms
  • [MeSH-minor] Capsule Endoscopy. Diagnosis, Differential. Female. Humans. Jejunum / pathology. Middle Aged. Occult Blood. Prognosis

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  • (PMID = 17147051.001).
  • [ISSN] 0009-9074
  • [Journal-full-title] La Clinica terapeutica
  • [ISO-abbreviation] Clin Ter
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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20. Hu JX, Miao XY, Zhong DW, Dai WD, Liu W, Hu W: Surgical treatment of primary duodenal adenocarcinoma. Hepatogastroenterology; 2006 Nov-Dec;53(72):858-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of primary duodenal adenocarcinoma.
  • BACKGROUND/AIMS: Our purpose was to review the outcome of the patients with primary duodenal adenocarcinoma and determine factors influencing survival.
  • Based on symptomology, primary duodenal adenocarcinoma may be classified into three categories: icteric, obstructive and illusive.
  • A curative resection was performed in 28 of the 43 patients (65.1%), a conventional pancreatoduodenectomy in 11, segmental duodenal resection in 16 and gastroduodenectomy in 1.
  • Pancreaticoduodenectomy is usually required for tumors of the first and second portion of the duodenum.
  • Segmental resection may be appropriate for selected patients, especially for cancers of the distal duodenum.
  • [MeSH-major] Adenocarcinoma / mortality. Adenocarcinoma / surgery. Duodenal Neoplasms / mortality. Duodenal Neoplasms / surgery

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  • (PMID = 17153441.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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21. Badía Bartolomé C, Díaz Formoso FJ, Rodríguez Falcón R, Marchena Gómez J: [Groove pancreatitis and its differential diagnosis with pancreatic adenocarcinoma]. Gastroenterol Hepatol; 2009 Jan;32(1):22-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Groove pancreatitis and its differential diagnosis with pancreatic adenocarcinoma].
  • [Transliterated title] Pancreatitis del surco y su diagnóstico diferencial con el adenocarcinoma de páncreas.
  • We analyzed the clinical, radiographic and histologic characteristics, as well as the difficulties that arose in the differential diagnosis between groove pancreatitis (a benign entity consisting of a segmental form of chronic pancreatitis occurring as a sheet-like scar in the area of pancreatoduodenal groove) and adenocarcinoma of the pancreas.
  • To this end, four cases with abnormalities in the groove area were retrospectively reviewed, three with groove pancreatitis, and one with adenocarcinoma of the pancreas.
  • [MeSH-major] Adenocarcinoma / diagnosis. Duodenitis / diagnosis. Pancreatic Neoplasms / diagnosis. Pancreatitis / diagnosis
  • [MeSH-minor] Adult. Aged. Biopsy, Fine-Needle. Cholangiopancreatography, Endoscopic Retrograde. Cholangiopancreatography, Magnetic Resonance. Cholelithiasis / complications. Cholelithiasis / diagnosis. Chronic Disease. Diagnosis, Differential. Duodenum / pathology. Fatal Outcome. Humans. Intestinal Mucosa / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Pancreaticoduodenectomy. Pancreatitis, Alcoholic / complications. Retrospective Studies

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  • [CommentIn] Gastroenterol Hepatol. 2009 Nov;32(9):662-3 [19525034.001]
  • (PMID = 19174095.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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22. Friedrich-Rust M, Jaeger C, Gossner L, May A, Günter E, Stolte M, Ell C: [Early duodenal adenocarcinoma arising in gastric metaplasia treated by endoscopic resection]. Z Gastroenterol; 2006 Apr;44(4):323-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Early duodenal adenocarcinoma arising in gastric metaplasia treated by endoscopic resection].
  • Early duodenal carcinoma is a rare entity.
  • Most duodenal carcinomas are diagnosed at a more advanced stage.
  • This report describes the case of a 59-year-old lady with an early duodenal adenocarcinoma diagnosed at check-up gastroduodenoscopy in an outpatient clinic who was referred to us for further investigation and management.
  • The initial upper endoscopy at our department revealed a type IIa+c lesion in the proximal duodenum (10 - 12 mm diameter, flat elevated lesion with central depression).
  • Histopathological examination revealed the rare entity of an early duodenal carcinoma arising from incomplete-type gastric metaplasia in the duodenum.
  • In summary, the presented paper describes a case of successful endoscopic treatment of an early duodenal carcinoma arising from incomplete gastric metaplasia.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery. Endoscopy, Gastrointestinal. Stomach / pathology

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  • (PMID = 16625461.001).
  • [ISSN] 0044-2771
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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23. Han SL, Cheng J, Zhou HZ, Zeng QQ, Lan SH: The surgical treatment and outcome for primary duodenal adenocarcinoma. J Gastrointest Cancer; 2010 Dec;41(4):243-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The surgical treatment and outcome for primary duodenal adenocarcinoma.
  • BACKGROUND: To investigate the early diagnosis and outcomes of surgical treatment of primary duodenal adenocarcinoma (PDAC) for curative purpose.
  • CONCLUSION: PD is suggested for tumor located at the first and second portion of the duodenum, and SR may be appropriate for the selected patients especially for tumors of the distal duodenum.
  • [MeSH-major] Adenocarcinoma / surgery. Digestive System Surgical Procedures. Duodenal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Treatment Outcome

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  • (PMID = 20431961.001).
  • [ISSN] 1941-6636
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Han SL, Cheng J, Zhou HZ, Zeng QQ, Lan SH: The surgical treatment and outcome for primary duodenal adenocarcinoma. J Gastrointest Cancer; 2009;40(1-2):33-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The surgical treatment and outcome for primary duodenal adenocarcinoma.
  • BACKGROUND: The purpose of this study was to investigate the early diagnosis and outcomes of surgical treatment of primary duodenal adenocarcinoma (PDAC) for curative purpose.
  • CONCLUSION: PD is suggested for tumor located at the first and second portion of the duodenum, and SR may be appropriate for the selected patients, especially for tumors of the distal duodenum.
  • [MeSH-major] Adenocarcinoma / mortality. Adenocarcinoma / surgery. Digestive System Surgical Procedures / methods. Duodenal Neoplasms / mortality. Duodenal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Treatment Outcome

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  • (PMID = 19513860.001).
  • [ISSN] 1941-6636
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Tsuchida K, Morinaga S, Sugano N, Shiozawa M, Akaike M, Sugimasa Y, Takemiya S, Hayashi H, Rino Y, Imada T: [A case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer]. Gan To Kagaku Ryoho; 2006 Nov;33(12):1878-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer].
  • Duodenal adenoma is rare, and there have been very few case reports of flat elevated type adenoma.
  • We report a case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer.
  • Endoscopic examination revealed the gastric cancer and a flat elevated tumor in the descending part of the duodenum, measuring 6 cm in diameter.
  • The biopsy specimen of the duodenal lesion was diagnosed as adenoma.
  • Distal gastrectomy and segmental partial resection of the duodenum were performed with no complication.
  • Histologically, the gastric cancer was poorly differentiated adenocarcinoma with submcosal invasion and without lymph node metastasis, and the duodenal tumor was a well differentiated carcinoma in villous adenoma.
  • The duodenal adenocarcinoma was limited to the mucosal layer and the resected margins were free of tumor.
  • It is difficult to distinguish a carcinoma from a benign elevated lesion in the duodenum.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Carcinoma / pathology. Duodenal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Stomach Neoplasms / pathology

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  • (PMID = 17212134.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 4
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26. Hakimi AN, Rosing DK, Stabile BE, Petrie BA: En bloc resection of the duodenum for locally advanced right colon adenocarcinoma. Am Surg; 2007 Oct;73(10):1063-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] En bloc resection of the duodenum for locally advanced right colon adenocarcinoma.
  • Direct invasion of colorectal adenocarcinoma into adjacent structures occurs frequently, but only rarely is the duodenum involved.
  • This study was undertaken to assess the safety and efficacy of en bloc resection of locally advanced right colon carcinoma invading the duodenum.
  • Forty-six patients underwent en bloc resection of colon and adjacent organs not involving the duodenum.
  • Three patients with duodenal invasion underwent en bloc partial duodenectomy.
  • Two patients with duodenal invasion are alive without recurrence at 15 and 20 months follow up.
  • En bloc resection of colon cancer invading the duodenum can be performed safely because morbidity and mortality rates are comparable to those attending extended resections of other locally advanced colon carcinomas.
  • Overall survival in patients who underwent surgery with curative intent justifies en bloc duodenal resection in selected patients.
  • [MeSH-major] Adenocarcinoma / surgery. Colonic Neoplasms / surgery. Duodenum / pathology. Duodenum / surgery
  • [MeSH-minor] Abdominal Pain / etiology. Abdominal Wall / pathology. Anemia / etiology. Female. Humans. Length of Stay. Male. Neoplasm Invasiveness. Peritoneum / pathology. Retrospective Studies. Survival Analysis

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  • (PMID = 17983082.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Busquets J, Fabregat J, Jorba R, Peláez N, García-Borobia F, Masuet C, Valls C, Martínez-Carnicero L, Lladó L, Torras J: [Surgical treatment of pancreatic adenocarcinoma by cephalic duodenopancreatectomy (Part 1). Post-surgical complications in 204 cases in a reference hospital]. Cir Esp; 2010 Nov;88(5):299-307
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  • [Title] [Surgical treatment of pancreatic adenocarcinoma by cephalic duodenopancreatectomy (Part 1). Post-surgical complications in 204 cases in a reference hospital].
  • [Transliterated title] Tratamiento quirúrgico del adenocarcinoma pancreático mediante duodenopancreatectomía cefálica (Parte 1). Complicaciones postoperatorias en 204 casos en un centro de referencia.
  • The aim of this article is to define variables that influence post-surgical morbidity and mortality after cephalic duodenopancreatectomy due to pancreatic adenocarcinoma (PA) cancer of the head of the pancreas (CHP).
  • [MeSH-major] Adenocarcinoma / surgery. Duodenum / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery

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  • [Copyright] Copyright © 2010 AEC. Published by Elsevier Espana. All rights reserved.
  • (PMID = 20663494.001).
  • [ISSN] 1578-147X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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28. Kajiwara M, Fujii S, Takahashi S, Konishi M, Nakagohri T, Gotohda N, Kinoshita T: Adenocarcinoma of the minor duodenal papilla with intraepithelial spread to the pancreatic duct. Virchows Arch; 2007 Dec;451(6):1075-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of the minor duodenal papilla with intraepithelial spread to the pancreatic duct.
  • It is extremely rare to encounter tumors arising exclusively in the minor duodenal papilla.
  • We report a 60-year-old male patient with a polypoid type of adenocarcinoma of the minor papilla.
  • On histology, an adenocarcinoma was located in the minor papilla, which was limited to the mucosa, without invasion of the duodenum, sphincter muscles of the minor papilla, or the underlying pancreas.
  • Although it is well known that adenocarcinoma of the duodenal papilla is sometimes accompanied by intraepithelial spread in the pancreatic duct, an adenocarcinoma arising in the minor papilla in this case with pancreas divisum was more extended than our thoughts.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Keratins / analysis. Magnetic Resonance Imaging. Male. Middle Aged. Mucin 5AC. Mucins / analysis. Pancreas / abnormalities. Pancreatic Diseases / congenital. Pancreatic Diseases / diagnosis. Pancreaticoduodenectomy. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17805567.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MUC5AC protein, human; 0 / Mucin 5AC; 0 / Mucins; 68238-35-7 / Keratins
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29. Khor TS, Brown I, Kattampallil J, Yusoff I, Kumarasinghe MP: Duodenal adenocarcinoma arising from a pyloric gland adenoma with a brief review of the literature. BMJ Case Rep; 2010;2010
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Duodenal adenocarcinoma arising from a pyloric gland adenoma with a brief review of the literature.
  • Pyloric gland-type adenoma of the duodenum with documented malignant progression is rare.
  • A case is presented of an 87-year-old man with bloating and nausea, who on investigation was found to have a polyp on the anteroinferior wall of the duodenal cap.
  • Histologic examination of the polyp showed features of a pyloric gland adenoma (PGA) demonstrating the full spectrum of progression from low- to high-grade dysplasia and finally invasive adenocarcinoma.
  • The literature on PGAs and the little documentations on progression to carcinoma in duodenal PGAs are reviewed.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Duodenal Neoplasms / pathology. Gastric Mucosa. Neoplasms, Multiple Primary / pathology. Stomach Neoplasms / pathology

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  • [Cites] Virchows Arch. 2004 Mar;444(3):224-30 [14758553.001]
  • [Cites] Virchows Arch. 1996 Jul;428(4-5):223-7 [8764930.001]
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  • (PMID = 22802482.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028104
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30. Pricop C, Lefter LP, Scripcariu V, Danciu M, Buleu D, Dragomir C: [Metachronous primary cancers of the colon and stomach]. Rev Med Chir Soc Med Nat Iasi; 2005 Oct-Dec;109(4):817-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report herein a case of 69 years old woman who, in the course of 11 years, developed two cancers: carcinoma of the colon fistulization in duodenum and adenocarcinoma of the stomach.
  • A decade later, she suffered a total gastrectomy with distal pancreatectomy for gastric adenocarcinoma.
  • Although patients with primary multiple cancers are not common, it is nonetheless important for clinicians to consider the possibility of metachronous cancers in patients who were treated for a primary malignant tumor.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma / surgery. Colonic Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Neoplasms, Second Primary / surgery. Stomach Neoplasms / surgery

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  • (PMID = 16610181.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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31. Murphy HR, Taylor W, Ellis A, Sturgess R: An unusual case of Turcot's syndrome associated with ileal adenocarcinoma, intestinal non-Hodgkin's lymphoma, and duodenal adenocarcinoma. Review of the classification and genetic basis of Turcot's syndrome. Fam Cancer; 2005;4(2):139-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An unusual case of Turcot's syndrome associated with ileal adenocarcinoma, intestinal non-Hodgkin's lymphoma, and duodenal adenocarcinoma. Review of the classification and genetic basis of Turcot's syndrome.
  • A 38-year-old man with a history of colonic and small bowel polyposis and glioblastoma was investigated for dyspepsia.
  • Upper GI endoscopy identified an abnormal area in the duodenum, confirmed by histology as high grade non-Hodgkin's B cell MALT lymphoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenomatous Polyposis Coli / pathology. Brain Neoplasms / pathology. Duodenal Neoplasms / pathology. Glioblastoma / pathology. Ileal Neoplasms / pathology. Intestinal Neoplasms / pathology. Lymphoma, B-Cell, Marginal Zone / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 15951965.001).
  • [ISSN] 1389-9600
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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32. Han SL, Cheng J, Zhou HZ, Zeng QQ, Lan SH: The surgical treatment and outcome for primary duodenal adenocarcinoma. J Gastrointest Cancer; 2008;39(1-4):46-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The surgical treatment and outcome for primary duodenal adenocarcinoma.
  • BACKGROUND: Primary duodenal adenocarcinomas (PDAC) are uncommon tumors characterized by non-specific symptoms and late diagnosis, and treatments of PDAC have some controversies.
  • METHOD: To investigate the early diagnosis and outcomes of surgical treatment of PDAC, 32 patients who were treated surgically between February 1990 and September 2006 were analyzed retrospectively.
  • CONCLUSION: PD is suggested for the tumor located at the first and second portion of the duodenum, and SR may be appropriate for the selected patients, especially for tumors of the distal duodenum.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery

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  • [ErratumIn] J Gastrointest Cancer. 2012 Jun;43(2):390
  • (PMID = 19399645.001).
  • [ISSN] 1941-6628
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Robinson A, Clark WF: A case report of gemcitabine treatment for duodenal cancer: the good (a sustained response) and the bad (life threatening refractory thrombotic thrombocytopenic purpura). J Gastrointest Cancer; 2010 Mar;41(1):71-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case report of gemcitabine treatment for duodenal cancer: the good (a sustained response) and the bad (life threatening refractory thrombotic thrombocytopenic purpura).
  • INTRODUCTION: Adenocarcinoma of the duodenum is a rare cancer and not submitted to the type of clinical trials that guide chemotherapy treatments in other gastrointestinal malignancies.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antimetabolites, Antineoplastic / adverse effects. Deoxycytidine / analogs & derivatives. Duodenal Neoplasms / drug therapy. Purpura, Thrombotic Thrombocytopenic / chemically induced

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  • (PMID = 19967470.001).
  • [ISSN] 1941-6636
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
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34. Shinoda M, Makino A, Wada M, Kabeshima Y, Takahashi T, Kawakubo H, Shito M, Sugiura H, Omori T: Successful endoscopic submucosal dissection for mucosal cancer of the duodenum. Dig Endosc; 2010 Jan;22(1):49-52
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  • [Title] Successful endoscopic submucosal dissection for mucosal cancer of the duodenum.
  • We report a case of mucosal duodenal cancer in a 62-year-old woman, which was successfully removed en bloc by endoscopic submucosal dissection (ESD).
  • The patient underwent an upper gastrointestinal endoscopy at our hospital, which revealed an elevated flat mucosal lesion (type IIa) measuring 10 mm in diameter in the second portion of the duodenum.
  • As the findings suggested that the lesion had an adenocarcinoma component but was confined to the mucosal layer, we decided to carry out ESD and successfully removed the tumor in one piece.
  • Histopathological examination revealed that the lesion was a well-differentiated mucosal adenocarcinoma with no lymphovascular invasion.
  • Mucosal duodenal cancer is extremely rare, and ESD of a lesion in the duodenum requires a high level of skill.
  • To the best of our knowledge, this case is the first report of successful ESD carried out in a case of mucosal duodenal cancer.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery. Endoscopy, Gastrointestinal. Gastric Mucosa / surgery

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  • (PMID = 20078665.001).
  • [ISSN] 1443-1661
  • [Journal-full-title] Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
  • [ISO-abbreviation] Dig Endosc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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35. Sunagawa H, Inamine S, Watanabe M, Kawakami K, Toyama T, Zaha H, Yonaha T, Ohta M, Oshiro N, Takeshima M, Uchima H: Carcinosarcoma of the duodenum: Report of a case. Surg Today; 2009;39(10):892-6
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  • [Title] Carcinosarcoma of the duodenum: Report of a case.
  • This report describes a case of carcinosarcoma of the duodenum.
  • Carcinosarcoma of the duodenum is a very rare tumor.
  • Endoscopy demonstrated an irregularly depressed lesion (type 3) in the descending portion of the duodenum opposite to the ampulla of Vater.
  • Computed tomography showed a thickened duodenal wall and swelling of the abdominal para-aortic lymph nodes.
  • A biopsy specimen revealed a well-differentiated adenocarcinoma.
  • A diagnosis of duodenal carcinoma was made (cT3, cN1, cM1, cStage IV according to the TNM classification).
  • On microscopic examination, adenocarcinoma cells and spindle type sarcoma cells were observed separately in the descending portion of the duodenum opposite to the ampulla of Vater.
  • The adenocarcinoma cells were stained with antibodies against epithelial markers keratin and carcinoembryonic antigen for immunohistochemical analyses.
  • The pathological diagnosis of a true duodenal carcinosarcoma was thus made.
  • [MeSH-major] Carcinosarcoma / diagnosis. Duodenal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Humans. Male. Neoplasm Staging

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  • (PMID = 19784730.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 16
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36. Miller G, Yim D, Macari M, Harris M, Shamamian P: Retroperitoneal perforation of the duodenum from biliary stent erosion. Curr Surg; 2005 Sep-Oct;62(5):512-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Retroperitoneal perforation of the duodenum from biliary stent erosion.
  • An unusual complication of indewelling biliary stents is duodenal perforation into the retroperitoneum.
  • We describe the case of a patient with end-stage pancreatic cancer who presented with an acute abdomen from erosion of a previously placed bile duct stent through the wall of the second portion of the duodenum.
  • Definitive diagnosis is best made with computed tomography (CT) imaging, which can detect traces of retroperitoneal air and fluid.
  • Complications of management can include duodenal fistulization, residual retroperitoneal or intrabdominal abscess, and ongoing sepsis.
  • This report highlights the salient issues in the presentation, diagnosis, and modern management of patients with this rare complication of indwelling biliary stents.
  • [MeSH-major] Duodenal Obstruction / etiology. Duodenal Obstruction / surgery. Foreign-Body Migration / surgery. Intestinal Perforation / etiology. Intestinal Perforation / surgery. Stents / adverse effects
  • [MeSH-minor] Abdominal Pain / diagnosis. Abdominal Pain / etiology. Adenocarcinoma / pathology. Adenocarcinoma / therapy. Aged. Follow-Up Studies. Humans. Jaundice, Obstructive / diagnosis. Jaundice, Obstructive / therapy. Laparotomy / methods. Male. Palliative Care. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / therapy. Retroperitoneal Space. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16125609.001).
  • [ISSN] 0149-7944
  • [Journal-full-title] Current surgery
  • [ISO-abbreviation] Curr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Murakami Y, Uemura K, Sasaki M, Morifuji M, Hayashidani Y, Sudo T, Sueda T: Duodenal cancer arising from the remaining duodenum after pylorus-preserving pancreatoduodenectomy for ampullary cancer in familial adenomatous polyposis. J Gastrointest Surg; 2005 Mar;9(3):389-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Duodenal cancer arising from the remaining duodenum after pylorus-preserving pancreatoduodenectomy for ampullary cancer in familial adenomatous polyposis.
  • We herein report a rare occurrence of duodenal cancer arising from the remaining duodenum after pylorus-preserving pancreatoduodenectomy for ampullary cancer in familial adenomatous polyposis (FAP).
  • During the current admission, the patient was diagnosed with adenocarcinoma in the Vater's ampulla using imaging and pathological examinations.
  • The tumor was a well-differentiated tubular adenocarcinoma and no other polyps were identified in the duodenum by pathological examination.
  • However, 1 year after surgery, a polypoid lesion measuring 15 x 15 mm was indicated in the remaining duodenum by endoscopic surveillance.
  • This lesion was completely resected by endoscopic mucosal resection and the resected specimen revealed well-differentiated tubular adenocarcinoma in an adenomatous lesion.
  • This report suggests that resection of the total duodenum is essential for duodenal neoplasms in FAP to prevent a recurrence in the remaining duodenum.
  • [MeSH-major] Adenocarcinoma / surgery. Adenomatous Polyposis Coli / secondary. Common Bile Duct Neoplasms / pathology. Duodenal Neoplasms / secondary. Duodenal Neoplasms / surgery. Pancreaticoduodenectomy / methods
  • [MeSH-minor] Adult. Ampulla of Vater / pathology. Cholangiopancreatography, Endoscopic Retrograde / methods. Duodenoscopy / methods. Female. Follow-Up Studies. Humans. Neoplasm, Residual / pathology. Neoplasm, Residual / surgery. Pylorus. Risk Assessment. Treatment Outcome

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  • (PMID = 15749602.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Tomita H, Osada S, Matsuo M, Shimokawa K: Pancreatic cancer presenting with hematemesis from directly invading the duodenum: report of an unusual manifestation and review. Am Surg; 2006 Apr;72(4):363-6
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  • [Title] Pancreatic cancer presenting with hematemesis from directly invading the duodenum: report of an unusual manifestation and review.
  • We report the case of a 67-year-old man with hematemesis who was found to have invasive pancreatic cancer with a bleeding duodenal ulcer.
  • Microscopic examination revealed that an adenocarcinoma originating from the pancreatic head extended to the muscularis propria of the duodenum.
  • The diagnosis, pathological findings, preoperative events, and postoperative outcome in this unusual case are reviewed.
  • [MeSH-major] Adenocarcinoma / pathology. Duodenum / pathology. Hematemesis / etiology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Aged. Cholecystectomy. Gallbladder / pathology. Humans. Male. Neoplasm Invasiveness. Pancreaticoduodenectomy

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  • (PMID = 16676866.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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39. Beger HG, Gansauge F, Siech M, Schwarz M, Poch B: Duodenum-preserving total pancreatic head resection for cystic neoplastic lesions in the head of the pancreas. J Hepatobiliary Pancreat Surg; 2008;15(2):149-56
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  • [Title] Duodenum-preserving total pancreatic head resection for cystic neoplastic lesions in the head of the pancreas.
  • Duodenum-preserving pancreatic head resection with segmental resection of the duodenum has been introduced for the surgical treatment of inflammatory and neoplastic lesions.
  • METHODS: Duodenum-preserving total pancreatic head resection (DPPHRt) with segmental resection of the duodenum (SD) was performed in eight patients, five with intraductal papillary mucinous neoplasm (IPMN), two with mucinous cystic neoplasm (MCN), and one with cystic endocrine neoplasm (EN).
  • RESULTS: Eight patients had a DPPHRt with SD resection, two patients had a resection of the uncinate process including segmental resection of the inferior duodenal segment, and one patient had a duodenum-and spleen-preserving total pancreatectomy.
  • CONCLUSIONS: Duodenum-preserving total pancreatic head resection for IPMN, MCN, serous cystadenoma (SCA), and cystic EN lesions is a safe and beneficial surgical procedure.
  • Segmental resection of the duodenum was applied for an oncologically complete resection.
  • [MeSH-major] Adenocarcinoma / surgery. Cysts / surgery. Duodenum / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery

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  • (PMID = 18392707.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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40. Yamamoto Y, Watanabe Y, Horiuchi A, Yoshida M, Yukumi S, Sato K, Nakagawa H, Sugishita H, Ishida N, Ishikawa M, Ishikawa K, Kawachi K: Adenoendocrine carcinoma of the accessory papilla of the duodenum: report of a case. Surg Today; 2009;39(5):425-9
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  • [Title] Adenoendocrine carcinoma of the accessory papilla of the duodenum: report of a case.
  • This report describes a very rare case of an adenoendocrine carcinoma of the accessory papilla of the duodenum.
  • Gastrointestinal endoscopy showed a protruding tumor with ulceration at the accessory papilla of the duodenum.
  • A biopsy revealed a small-cell carcinoma.
  • Microscopically, the tumor was a small-cell neuroendocrine carcinoma with adenomatous differentiation.
  • The final diagnosis was an adenoendocrine carcinoma with lymph node metastasis.
  • [MeSH-major] Adenocarcinoma, Papillary / diagnosis. Carcinoma, Neuroendocrine / diagnosis. Duodenal Neoplasms / diagnosis. Endocrine Glands / pathology

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  • (PMID = 19408082.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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41. Wakatsuki T, Irisawa A, Takagi T, Koyama Y, Hoshi S, Takenoshita S, Abe M, Ohira H: Primary adenocarcinoma of the minor duodenal papilla. Yonsei Med J; 2008 Apr 30;49(2):333-6
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  • [Title] Primary adenocarcinoma of the minor duodenal papilla.
  • Upper gastrointestinal endoscopy revealed a flat elevated tumor with central ulceration in the second portion of the duodenum.
  • Subsequent duodenoscopy for a more detailed examination showed that the tumor had originated in the minor duodenal papilla.
  • A biopsy specimen showed moderately differentiated adenocarcinoma.
  • Endoscopic retrograde pancreatography via the major duodenal papilla revealed a slightly dilated main pancreatic duct and obstruction of the accessory pancreatic duct.
  • Endoscopic ultrasonography showed a hypoechoic mass in the minor duodenal papilla with retention of the muscularis propria of the duodenum.
  • These findings suggest that the tumor existed only to a limited extent in the minor duodenal papilla, and that the tumor did not infiltrate into the pancreas.
  • For treatment, pylorus-preserving pancreatoduodenectomy was performed, and histological findings revealed a well-differentiated adenocarcinoma that originated in the minor duodenal papilla.
  • Primary adenocarcinoma of the minor duodenal papilla is extremely rare.
  • Our case is the first report of primary adenocarcinoma of the minor duodenal papilla at an early stage with no infiltration into muscularis propria of the duodenum and pancreas.
  • [MeSH-major] Adenocarcinoma / pathology. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 18452274.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2615313
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42. Nojima H, Shimizu H, Kimura F, Yoshidome H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takeuchi D, Takayashiki T, Suda K, Takano S, Kuboki S, Kato M, Miyazaki M: [A resected case of non-invasive type of intraductal papillary mucinous carcinoma penetrating to the duodenum]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2376-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A resected case of non-invasive type of intraductal papillary mucinous carcinoma penetrating to the duodenum].
  • Endoscopy revealed a fistula filled with mucin in the posterior wall of the duodenum.
  • Endoscopic ultrasonography revealed dilation of the pancreatic duct and also mural nodules in the pancreatic duct, ERP demonstrated a fistula from the pancreatic duct to the duodenum.
  • We performed pancreaticoduodenectomy for main-duct IPMN penetrating to the duodenum.
  • Furthermore, a cancer invasion to the duodenum was not detected.
  • These findings suggest that the increased pressure within the pancreatic duct caused a fistula to the duodenum.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology. Duodenal Diseases / etiology. Intestinal Fistula / etiology. Pancreatic Fistula / etiology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Aged. Duodenum / pathology. Humans. Male. Pancreaticoduodenectomy

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  • (PMID = 21224578.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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43. Hol JW, Stuifbergen WN, Teepen JL, van Laarhoven CJ: Giant Brunner's hamartomas of the duodenum and obstructive jaundice. An overview of the literature and suspicion of malignancy in a case. Dig Surg; 2007;24(6):452-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant Brunner's hamartomas of the duodenum and obstructive jaundice. An overview of the literature and suspicion of malignancy in a case.
  • METHODS: In this case report, a 60-year-old male is presented with unexplained obstructive jaundice who was also known for over 17 years with diffuse adenomatous hyperplasia of Brunner's glands in the duodenum.
  • Despite the benign preoperative diagnosis, the choice of treatment was Whipple's procedure due to suspicion of a coexisting malignancy.
  • RESULTS: Pathological analysis of the resection specimen revealed multiple BGHs and an adenocarcinoma of the papilla of Vater (PoV).
  • CONCLUSION: It is likely that previous reports of malignant degeneration of BGHs may actually have been cases involving the coexistence of a PoV adenocarcinoma.
  • Physicians need to be alert when a patient presents with BGH accompanied with obstructive jaundice for simultaneously occurring PoV adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / epidemiology. Ampulla of Vater. Brunner Glands. Common Bile Duct Neoplasms / epidemiology. Duodenal Diseases / epidemiology. Hamartoma / epidemiology. Jaundice, Obstructive / etiology
  • [MeSH-minor] Comorbidity. Digestive System Surgical Procedures. Dilatation, Pathologic. Duodenum / pathology. Duodenum / radiography. Humans. Hypertrophy. Male. Middle Aged. Tomography, X-Ray Computed

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  • [Copyright] Copyright (c) 2007 S. Karger AG, Basel
  • (PMID = 18025786.001).
  • [ISSN] 1421-9883
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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44. Yagyu T, Aihara T, Murayama M, Kikuchi S, Nakamura E, Hase K, Hatsuse K, Tamura K, Mochizuki H: Mucinous carcinoma of the duodenum associated with hereditary nonpolyposis colorectal cancer: report of a case. Surg Today; 2006;36(12):1129-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucinous carcinoma of the duodenum associated with hereditary nonpolyposis colorectal cancer: report of a case.
  • We herein report a rare case of primary mucinous carcinoma of the duodenum associated with hereditary nonpolyposis colorectal cancer (HNPCC).
  • A 50-year-old man known to have HNPCC based on the Amsterdam criteria I was admitted because of the presence of a duodenal tumor.
  • Duodenoscopy revealed an ulcerated tumor in the posterior wall of the second portion of the duodenum and the malignancy was confirmed by a biopsy.
  • The histological diagnosis was mucinous carcinoma of the duodenum with lymph node metastasis.
  • High-frequency microsatellite instability (MSI-H) was identified in both the colon and a duodenal specimen based on a microsatellite assay.
  • Even though extracolonic malignancies are associated with HNPCC, duodenal cancer is nevertheless very rare, and only two cases have been reported over the past 20 years.
  • [MeSH-major] Adenocarcinoma, Mucinous / complications. Colorectal Neoplasms, Hereditary Nonpolyposis / complications. Duodenal Neoplasms / complications
  • [MeSH-minor] Diagnosis, Differential. Endoscopy, Gastrointestinal. Endosonography. Follow-Up Studies. Humans. Male. Middle Aged. Pancreaticoduodenectomy


45. Ichimura T, Kondo S, Okamura K, Tanaka E, Hirano S: Total parenchymal pancreatectomy preserving the duodenum, choledochus and spleen for widespread intraductal papillary mucinous neoplasm: report of a case. Hepatogastroenterology; 2010 Jan-Feb;57(97):8-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Total parenchymal pancreatectomy preserving the duodenum, choledochus and spleen for widespread intraductal papillary mucinous neoplasm: report of a case.
  • For patients with benign or low malignant diseases of the pancreas, several organ-preserving surgical techniques of pancreatectomy have been presented for localized lesions.
  • We herein report a patient with widespread intraductal papillary mucinous neoplasm treated successfully with total parenchymal pancreatectomy.
  • A 73-year-old man was diagnosed as main duct intraductal papillary mucinous neoplasm.
  • We performed total parenchymal pancreatectomy, an initial surgical procedure in which almost all parenchyma of the pancreas was resected but the duodenum, the common bile duct and the spleen were preserved and no reconstruction was needed.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Pancreatectomy. Pancreatic Neoplasms / surgery
  • [MeSH-minor] Aged. Common Bile Duct. Duodenum. Humans. Male. Spleen

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  • (PMID = 20422863.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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46. Yang WL, Yan CQ, Zhang HG, Wang FJ, Ma YL: [Surgical treatment and prognosis of cancer of hepatic flexure of colon invading the duodenum in 65 patients]. Zhonghua Zhong Liu Za Zhi; 2009 Nov;31(11):873-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment and prognosis of cancer of hepatic flexure of colon invading the duodenum in 65 patients].
  • OBJECTIVE: To discuss surgical treatment of right colon carcinoma of hepatic flexure invading the duodenum.
  • METHODS: Sixty-five patients with right colon carcinoma of hepatic flexure invading the duodenum, treated in our department from 1987 to 2007, were included in this study.
  • All the cases were divided into three types (local invasion, regional invasion, and cancer with internal fistula) according to duodenal defect, including local invasion (< 2.0 cm), wide invasion (> 2.0 cm) and the presence of internal fistula.
  • RESULTS: 25 patients with local invasion underwent en bloc resection of the duodenal wall.
  • Pedicled ileal flap was used to cover the large duodenal defect measuring 2.0 - 3.0 cm in 5 patients.
  • 10 underwent duodenal diverticularization.
  • CONCLUSION: The surgical procedure to be performed is usually decided according to the cancer location, extent, and duodenal defect and invasion, which are important for prolonging life time, improving of quality of life and prognosis in these patients.
  • [MeSH-major] Adenocarcinoma / surgery. Colon, Ascending / surgery. Colonic Neoplasms / surgery. Duodenum / surgery
  • [MeSH-minor] Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / surgery. Adult. Aged. Colectomy / methods. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness. Pancreaticoduodenectomy. Quality of Life. Retrospective Studies. Survival Rate

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  • (PMID = 20137356.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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47. Nihon-Yanagi Y, Park Y, Ooshiro M, Aoki H, Suzuki Y, Hiruta N, Kameda N, Katoh R: A case of recurrent invasive lobular carcinoma of the breast found as metastasis to the duodenum. Breast Cancer; 2009;16(1):83-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of recurrent invasive lobular carcinoma of the breast found as metastasis to the duodenum.
  • Computed tomography (CT) of the abdomen revealed an enlarged duodenum and dilated intrahepatic biliary and pancreatic ducts.
  • Upper gastrointestinal endoscopy showed edema of the duodenum.
  • A biopsy yielded a diagnosis of poorly differentiated adenocarcinoma.
  • Duodenal carcinoma was suspected, and a pancreatoduodenectomy was performed.
  • Duodenal metastasis from invasive lobular carcinoma was diagnosed on postoperative histopathological examination.
  • We describe our experience with a patient in whom invasive lobular carcinoma of the breast with metastasis to the duodenal wall was definitively diagnosed on laparotomy.
  • [MeSH-major] Breast Neoplasms / pathology. Carcinoma, Lobular / pathology. Carcinoma, Lobular / secondary. Duodenal Neoplasms / secondary. Neoplasm Recurrence, Local / pathology

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  • (PMID = 18386118.001).
  • [ISSN] 1880-4233
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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48. Zins M, Loriau J, Boulay-Coletta I, Julles M, Petit E, Sauvanet A: [Postoperative imaging of the pancreas and duodenum]. J Radiol; 2009 Jul-Aug;90(7-8 Pt 2):918-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Postoperative imaging of the pancreas and duodenum].
  • Pancreatic surgery is a frequent therapeutic approach for benign and malignant conditions.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenum / surgery. Pancreas / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods. Postoperative Complications / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 19752831.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 57
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49. Shimizu M, Kawaguchi A, Nagao S, Hozumi H, Komoto S, Hokari R, Miura S, Hatsuse K, Ogata S: A case of intraductal papillary mucinous neoplasm of the pancreas rupturing both the stomach and duodenum. Gastrointest Endosc; 2010 Feb;71(2):406-12
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  • [Title] A case of intraductal papillary mucinous neoplasm of the pancreas rupturing both the stomach and duodenum.
  • BACKGROUND: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas may extend to other organs.
  • There has been no report of a benign IPMN rupturing both the stomach and duodenum.
  • Intraluminal nodular growth was observed in the duodenal gland tissue, and abnormal growth was observed in the fistula to the stomach.
  • [MeSH-major] Adenocarcinoma, Mucinous / secondary. Carcinoma, Pancreatic Ductal / secondary. Carcinoma, Papillary / secondary. Duodenal Neoplasms / secondary. Pancreatic Neoplasms / pathology. Stomach Neoplasms / secondary
  • [MeSH-minor] Aged. Cholangiopancreatography, Endoscopic Retrograde / methods. Endosonography / methods. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness / pathology. Pancreaticoduodenectomy / methods. Rare Diseases. Risk Assessment. Rupture, Spontaneous / etiology. Rupture, Spontaneous / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19922925.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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50. Miller AD, Kramer JA, Lin KC, Knight H, Martinot A, Mansfield KG: Small intestinal adenocarcinoma in common marmosets (Callithrix jacchus). Vet Pathol; 2010 Sep;47(5):969-76
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  • [Title] Small intestinal adenocarcinoma in common marmosets (Callithrix jacchus).
  • Small intestinal adenocarcinomas are uncommon neoplasms that are rarely reported in nonhuman primates.
  • Herein the authors report the clinical, histologic, immunohistochemical, and molecular characteristics of small intestinal adenocarcinoma in 10 common marmosets (Callithrix jacchus).
  • Retrospective analysis of necropsy records revealed small intestinal carcinoma to be the most common neoplastic cause of morbidity and mortality in aged common marmosets.
  • Nine of 10 (90%) tumors arose within the proximal small intestine near the interface with the duodenum.
  • The tumors described in this population illustrate comparable features to human cases of small intestine carcinoma and may serve as a potential animal model for small intestinal carcinomas.

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  • [Cites] J Clin Microbiol. 1999 Jan;37(1):146-51 [9854080.001]
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  • (PMID = 20460447.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / T32 RR007000-35; United States / NCRR NIH HHS / RR / P51 RR000168-50; United States / NCRR NIH HHS / RR / T32 RR007000; United States / NCRR NIH HHS / RR / RR00168; United States / NCRR NIH HHS / RR / P51 RR000168; United States / NCRR NIH HHS / RR / K26 RR000168; United States / NCRR NIH HHS / RR / RR07000
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  • [Other-IDs] NLM/ NIHMS235944; NLM/ PMC2955325
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51. Wada K, Takada T, Amano H, Yoshida M, Miura F, Toyota N, Kato K, Isaka T, Nagashima I: [Trend in the management of pancreatic adenocarcinoma--Japan vs. US and Europe]. Nihon Geka Gakkai Zasshi; 2006 Jul;107(4):187-91
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  • [Title] [Trend in the management of pancreatic adenocarcinoma--Japan vs. US and Europe].
  • Pancreatic adenocarcinoma remains to have poor prognosis.
  • Current rationale for the treatment of pancreatic adenocarcinoma in the US and European countries consists of the following formula:.
  • [MeSH-major] Adenocarcinoma / therapy. Pancreatic Neoplasms / therapy
  • [MeSH-minor] Combined Modality Therapy / trends. Duodenum / surgery. Europe. Humans. Japan. Lymph Node Excision. Myenteric Plexus / surgery. Neoplasm Staging. Pancreatectomy. Portal Vein / surgery. Survival Rate. United States

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  • (PMID = 16878412.001).
  • [ISSN] 0301-4894
  • [Journal-full-title] Nihon Geka Gakkai zasshi
  • [ISO-abbreviation] Nihon Geka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 21
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52. Okumura F, Senoo K, Yoshida M, Miyabe K, Naito I, Tanaka H, Hayashi K, Ando T, Nakazawa T, Ohara H, Hamaguchi K, Kanai M, Ito K, Joh T: [A case of peritoneal dissemination from mucinous carcinoma of the duodenum, which was associated with tumor thrombosis in the accessory pancreatic duct and successfully treated by chemotherapy]. Nihon Shokakibyo Gakkai Zasshi; 2009 Dec;106(12):1736-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of peritoneal dissemination from mucinous carcinoma of the duodenum, which was associated with tumor thrombosis in the accessory pancreatic duct and successfully treated by chemotherapy].
  • Endoscopic examination of the upper gastrointestinal tract revealed a type 3 tumor in the descending limb of the duodenum.
  • A diagnosis of adenocarcinoma was made on the basis of the histological analysis of the biopsy sample.
  • The pathological findings indicated primary duodenal cancer (mucinous carcinoma) associated with tumor thrombosis in the accessory pancreatic duct.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Duodenal Neoplasms / pathology. Neoplastic Cells, Circulating / pathology. Pancreatic Ducts / pathology. Peritoneal Neoplasms / secondary

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  • (PMID = 19966515.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 30
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53. Overman MJ, Fogelman D, Al-Kali A, Crane CH, Evans D, Abdalla EK, Pisters P, Kopetz S, Eng C, Wolff RA: Aggressive combined modality therapy for recurrent colorectal cancer involving the duodenum and pancreas: a report of 5 cases. Clin Colorectal Cancer; 2008 Sep;7(5):338-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive combined modality therapy for recurrent colorectal cancer involving the duodenum and pancreas: a report of 5 cases.
  • We report 5 cases in which the recurrence of colorectal cancer (CRC) presented as a mass involving the duodenum and pancreas.
  • Such trimodality therapy can result in durable palliation of symptoms and long-term survival for patients with recurrent CRC involving the duodenum and pancreas, even when other metastases are present.
  • [MeSH-major] Adenocarcinoma / therapy. Colorectal Neoplasms / therapy. Duodenal Neoplasms / therapy. Neoplasm Recurrence, Local / therapy. Pancreatic Neoplasms / therapy


54. Miyashita T, Ohta T, Fujimura T, Ninomiya I, Fushida S, Hattori T, Miwa K: Duodenal juice stimulates oesophageal stem cells to induce Barrett's oesophagus and oesophageal adenocarcinoma in rats. Oncol Rep; 2006 Jun;15(6):1469-75
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  • [Title] Duodenal juice stimulates oesophageal stem cells to induce Barrett's oesophagus and oesophageal adenocarcinoma in rats.
  • the present study was performed to examine the sequential process of the development of Barrett's oesophagus (BE) and oesophageal adenocarcinoma (ADC) induced by duodeno-oesophageal reflux (DER) in rats.
  • [MeSH-major] Adenocarcinoma / etiology. Barrett Esophagus / etiology. Duodenogastric Reflux / complications. Duodenum / secretion. Esophageal Neoplasms / etiology. Esophagus / pathology. Gastroesophageal Reflux / complications. Stem Cells / pathology

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  • (PMID = 16685381.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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55. Solej M, D'Amico S, Brondino G, Ferronato M, Nano M: Primary duodenal adenocarcinoma. Tumori; 2008 Nov-Dec;94(6):779-86
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary duodenal adenocarcinoma.
  • AIMS AND BACKGROUND: Primary duodenal adenocarcinoma is a rare tumor with a poorly defined natural history and prognostic factors.
  • It presents with nonspecific symptoms, and for this reason the diagnosis is often delayed.
  • It is a serious problem for the surgeon because of the difficulty in obtaining an early diagnosis and standardizing basic tenets for an appropriate surgical approach.
  • METHODS AND STUDY DESIGN: A bibliographic search was carried out on the main search engines to find studies regarding duodenal adenocarcinoma, published in English, from January 1992 to January 2007.
  • Hopefully, an early diagnosis will correlate with improved long-term survival.
  • [MeSH-major] Adenocarcinoma / pathology. Duodenal Neoplasms / pathology

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  • (PMID = 19267092.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 19
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56. Wang Y, Xie SL, Wang CF, Liu SM, Shan Y, Zhao DB, Liu Q, Luo W, Zhao P: [Clinical and pathological analysis of 114 cases with non-ductal pancreatic adenocarcinoma occupying lesions]. Zhonghua Yi Xue Za Zhi; 2010 Apr 27;90(16):1089-92
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  • [Title] [Clinical and pathological analysis of 114 cases with non-ductal pancreatic adenocarcinoma occupying lesions].
  • OBJECTIVE: To improve the diagnosis and treatment of non-ductal pancreatic adenocarcinoma-occupying lesions.
  • METHODS: A retrospective analysis was made for 114 cases of pancreatic non-ductal adenocarcinoma-occupying pathologically confirmed lesions. RESULTS:.
  • (4) pancreaticoduodenectomy was performed in 26 patients, distal pancreatectomy in 53, tumor enucleation in 15, segmental pancreatectomy in 9, partial resection in 3, duodenum-preserving pancreatic head resection in 1 and palliative surgery (either cholecystojejunostomy anastomosis or gastrojejunostomy) in 7;.
  • (5) pathologic analysis revealed 35 solid pseudopapillary neoplasm of pancreas, 28 pancreatic endocrine tumors, 18 focal chronic pancreatitis, 11 serous cystic neoplasms, 9 mucinous cystic neoplasms, 4 pancreatic cysts, 3 acinar cell carcinomas, 2 pancreatic cavernous hemangiomas, 1 sarcoma of pancreas, 1 sarcomatoid carcinoma of pancreas, 1 pancreatic schwannoma and 1 pancreatic neuroblastoma.
  • CONCLUSION: The non-ductal pancreatic adenocarcinoma-occupying lesions have no specific clinical presentation or serum tumor marker.

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  • (PMID = 20646423.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-19-9 Antigen
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57. Leys CM, Nomura S, Rudzinski E, Kaminishi M, Montgomery E, Washington MK, Goldenring JR: Expression of Pdx-1 in human gastric metaplasia and gastric adenocarcinoma. Hum Pathol; 2006 Sep;37(9):1162-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of Pdx-1 in human gastric metaplasia and gastric adenocarcinoma.
  • The transcription factor Pdx-1 is expressed in the adult pancreatic islet cells as well as the gastric antrum and duodenum.
  • We have therefore sought to examine the presence of Pdx-1 expression in gastric metaplasias and gastric adenocarcinoma in humans.
  • Given the pattern of normal Pdx-1 expression in the duodenum, goblet cell metaplasia in the stomach may reflect the adoption of a duodenal lineage paradigm.
  • [MeSH-major] Adenocarcinoma / metabolism. Homeodomain Proteins / biosynthesis. Precancerous Conditions / metabolism. Stomach Neoplasms / metabolism. Trans-Activators / biosynthesis

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  • (PMID = 16938521.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / 1P 50 CA95103; United States / NCI NIH HHS / CA / K12 CA090625
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Homeodomain Proteins; 0 / Trans-Activators; 0 / pancreatic and duodenal homeobox 1 protein
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58. Srilatha PS: Concurrence of duodenal carcinoid and diffuse gastric adenocarcinoma: a rare phenomenon. Saudi J Gastroenterol; 2007 Oct-Dec;13(4):197-9

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  • [Title] Concurrence of duodenal carcinoid and diffuse gastric adenocarcinoma: a rare phenomenon.
  • There are a few studies, which highlight the incidental finding of the yellow beauty-the "carcinoid" of the duodenum simultaneously occurring with the venomous "diffuse gastric adenocarcinoma".

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  • (PMID = 19858647.001).
  • [ISSN] 1998-4049
  • [Journal-full-title] Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
  • [ISO-abbreviation] Saudi J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
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59. Agrawal S, McCarron EC, Gibbs JF, Nava HR, Wilding GE, Rajput A: Surgical management and outcome in primary adenocarcinoma of the small bowel. Ann Surg Oncol; 2007 Aug;14(8):2263-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management and outcome in primary adenocarcinoma of the small bowel.
  • BACKGROUND: Primary adenocarcinoma of the small bowel is a rare malignancy and is associated with poor survival outcome.
  • METHODS: Between 1971 and 2005, 64 patients with primary adenocarcinoma of the small bowel were treated at our institution.
  • The most frequently involved portion of the small bowel was the duodenum (n = 41; 64%).
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Adenocarcinoma / surgery. Intestinal Neoplasms / diagnosis. Intestinal Neoplasms / pathology. Intestinal Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Lymphatic Metastasis. Male. Middle Aged. Multivariate Analysis. Neoplasm Recurrence, Local. Neoplasm Staging. Prognosis. Survival Rate. Time Factors. Treatment Outcome

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  • (PMID = 17549572.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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60. Koizumi M, Sata N, Yoshizawa K, Kurihara K, Yasuda Y: Carcinoma Arising from Brunner's Gland in the Duodenum after 17 Years of Observation - A Case Report and Literature Review. Case Rep Gastroenterol; 2007;1(1):103-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoma Arising from Brunner's Gland in the Duodenum after 17 Years of Observation - A Case Report and Literature Review.
  • Esophagogastroduodenoscopy (EGD) detected a small protruding lesion in the duodenal bulb, which was diagnosed as Brunner's adenoma.
  • The lesion had changed shape to become a 10 mm sessile tumor with a central depression, and following a biopsy was diagnosed as an adenocarcinoma.
  • The patient underwent partial resection of the duodenum.
  • This is an extremely rare case of primary duodenal carcinoma arising from Brunner's gland in a patient observed for 17 years.

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  • (PMID = 21487554.001).
  • [ISSN] 1662-0631
  • [Journal-full-title] Case reports in gastroenterology
  • [ISO-abbreviation] Case Rep Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3073796
  • [Keywords] NOTNLM ; Adenocarcinoma / Brunner's gland / Duodenal cancer
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61. Goswami RS, Minoo P, Baker K, Chong G, Foulkes WD, Jass JR: Hyperplastic polyposis and cancer of the colon with gastrinoma of the duodenum. Nat Clin Pract Oncol; 2006 May;3(5):281-4; quiz 285
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hyperplastic polyposis and cancer of the colon with gastrinoma of the duodenum.
  • DIAGNOSIS: Duodenal neuroendocrine neoplasm showing gastrin expression and stage III (T3N2M0), poorly differentiated adenocarcinoma of the cecum arising from hyperplastic polyposis.
  • MANAGEMENT: Right-sided hemicolectomy with ileocolonic anastomosis, duodenal resection, leucovorin and 5-fluorouracil chemotherapy, annual colonoscopic surveillance, and polypectomy.
  • [MeSH-major] Adenocarcinoma. Colonic Neoplasms. Colonic Polyps. Duodenal Neoplasms. Gastrinoma. Neoplasms, Multiple Primary
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colectomy. Diagnosis, Differential. Female. Humans. Hyperplasia. Middle Aged. Treatment Outcome. Zollinger-Ellison Syndrome / diagnosis

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  • (PMID = 16683006.001).
  • [ISSN] 1743-4254
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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62. Alibegov RA, Prokhorenko TI, Sergeev OA, Khlusov AN: [Clinico-morphological factors of prognosis in cancer of the major duodenum papilla]. Vestn Khir Im I I Grek; 2008;167(2):26-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinico-morphological factors of prognosis in cancer of the major duodenum papilla].
  • Long-term results of radical operative treatment of 19 patients with cancer of the major duodenal papilla were analyzed.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Pancreaticoduodenectomy / methods
  • [MeSH-minor] Disease Progression. Female. Follow-Up Studies. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging / methods. Pancreatic Neoplasms / pathology. Prognosis. Retrospective Studies. Russia / epidemiology. Survival Rate. Time Factors. Treatment Outcome

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  • (PMID = 18522181.001).
  • [ISSN] 0042-4625
  • [Journal-full-title] Vestnik khirurgii imeni I. I. Grekova
  • [ISO-abbreviation] Vestn. Khir. Im. I. I. Grek.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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63. Naseef O, Adham M, Hervieu V, Le Borgne J, Partensky C: Long-term survival (superior to 20 years) after pancreaticoduodenectomy for pancreatic duct adenocarcinoma: report of two cases. Hepatogastroenterology; 2008 May-Jun;55(84):1110-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term survival (superior to 20 years) after pancreaticoduodenectomy for pancreatic duct adenocarcinoma: report of two cases.
  • Pancreatic duct adenocarcinoma (PDA) is associated with dismal survival.
  • [MeSH-minor] Adult. Antibodies, Monoclonal / therapeutic use. Combined Modality Therapy. Disease-Free Survival. Duodenum / pathology. Humans. Immunotherapy. Lymph Nodes / pathology. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Radiotherapy, Adjuvant. Radiotherapy, High-Energy

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  • (PMID = 18705340.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal
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64. Takahashi T, Ando T, Kabeshima Y, Kawakubo H, Shito M, Sugiura H, Omori T: Borderline cases between benignancy and malignancy of the duodenum diagnosed successfully by endoscopic submucosal dissection. Scand J Gastroenterol; 2009;44(11):1377-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Borderline cases between benignancy and malignancy of the duodenum diagnosed successfully by endoscopic submucosal dissection.
  • OBJECTIVE. Due to advances in endoscopic equipment, primary duodenal tumors are found more frequently than in the past.
  • We performed endoscopic submucosal dissection (ESD) to diagnose and treat four non-ampullary duodenal tumors.
  • CONCLUSIONS. Since tissue obtained from endoscopic biopsies can sometimes prove difficult for definitive histological diagnosis, ESD may play an important role in the management of cases appearing to border on malignancy.
  • In addition, ESD allows for minimally invasive treatment without sacrificing the possibility of cure for duodenal carcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Dissection / methods. Duodenal Neoplasms / diagnosis. Endoscopy, Gastrointestinal / methods. Intestinal Mucosa / pathology
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male

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  • (PMID = 19821793.001).
  • [ISSN] 1502-7708
  • [Journal-full-title] Scandinavian journal of gastroenterology
  • [ISO-abbreviation] Scand. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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65. Cardona DM, Zhang X, Liu C: Loss of carbamoyl phosphate synthetase I in small-intestinal adenocarcinoma. Am J Clin Pathol; 2009 Dec;132(6):877-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Loss of carbamoyl phosphate synthetase I in small-intestinal adenocarcinoma.
  • Carbamoyl phosphate synthetase I (CPS1), normally found in hepatocytes and small-intestine (SI) enterocytes, is the antigen of Hep Par 1 antibody.
  • Expression of CPS1 in invasive SI adenocarcinoma seems to be lost.
  • The differential expression of Hep Par 1 in dysplastic vs malignant tumors of the SI may be diagnostically useful in difficult cases.
  • [MeSH-major] Adenocarcinoma / enzymology. Carbamoyl-Phosphate Synthase (Ammonia) / metabolism. Duodenal Neoplasms / enzymology. Duodenum / enzymology
  • [MeSH-minor] Adenoma / enzymology. Adenoma / pathology. Biomarkers, Tumor / metabolism. Duodenitis / enzymology. Duodenitis / pathology. Humans. Immunohistochemistry. Intestinal Mucosa / enzymology. Intestinal Mucosa / pathology. Neoplasm Invasiveness. Retrospective Studies

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  • (PMID = 19926579.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 6.3.4.16 / Carbamoyl-Phosphate Synthase (Ammonia)
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66. Lee CH, Kim PS, Lee JI, Jeong S, Lee JW, Kwon KS, Lee DH, Kim HG, Shin YW, Kim YS, Kim JM, Jeon YS: [A case of primary jejunal adenocarcinoma diagnosed by enteroscopy using pediatric colonoscope]. Korean J Gastroenterol; 2006 Nov;48(5):365-8
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  • [Title] [A case of primary jejunal adenocarcinoma diagnosed by enteroscopy using pediatric colonoscope].
  • On endoscopic examination, there was large amount of bile stained fluid in duodenum.
  • Endoscopic jejunal biopsy showed moderately differentiated adenocarcinoma.
  • Small intestinal adenocarcinoma is uncommonly encountered in clinical practice.
  • Because small intestine is relatively inaccessible via routine endoscopy, diagnosis of small intestinal neoplasm is often delayed for several months after the onset of symptoms.
  • Therefore, when a small bowel neoplasm is suspected, enteroscopy is the most useful study.
  • If enteroscope is not available, enteroscopy using pediatric colonoscope may permit earlier preoperative diagnosis.
  • We report a case of primary jejunal adenocarcinoma diagnosed by endoscopic biopsy using pediatric colonoscope.
  • [MeSH-major] Adenocarcinoma / pathology. Jejunal Neoplasms / pathology

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  • (PMID = 17132927.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
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67. Liao MT, Cheng MF, Chang WC, Wu YC, Lee HS, Tsai SH: Duodenal mantle cell lymphoma in a patient with advanced sigmoid adenocarcinoma. South Med J; 2009 Apr;102(4):429-31
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  • [Title] Duodenal mantle cell lymphoma in a patient with advanced sigmoid adenocarcinoma.
  • While colorectal cancer is one of the most commonly encountered gastrointestinal malignancies, primary lymphoma is an uncommon neoplasm of the gastrointestinal tract.
  • The duodenum is not a common location for the recurrence of colon cancer or of primary gastrointestinal lymphoma.
  • Here we report a patient who received concurrent chemoradiotherapy for his advanced sigmoid adenocarcinoma and developed MCL in the duodenal bulb 20 months later.
  • Suspected lesions should be biopsied and examined for a secondary neoplasm, especially when they appear in an uncommon location for metastasis or direct invasion.
  • [MeSH-major] Adenocarcinoma / diagnosis. Colon, Sigmoid / pathology. Colonic Neoplasms / diagnosis. Duodenum / pathology. Lymphoma, Mantle-Cell / diagnosis
  • [MeSH-minor] Aged. Contrast Media. Diagnosis, Differential. Fatal Outcome. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 19279526.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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68. Kargi A, Gürel D, Akkoclu A, Sanli A, Yilmaz E: Primary pulmonary extranodal marginal zone lymphoma/low grade B-cell lymphoma of MALT type combined with well-differentiated adenocarcinoma. Tumori; 2010 Jan-Feb;96(1):168-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary pulmonary extranodal marginal zone lymphoma/low grade B-cell lymphoma of MALT type combined with well-differentiated adenocarcinoma.
  • We describe a rare case of extranodal marginal zone/low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) combined with areas of well-differentiated adenocarcinoma.
  • In addition, the MALT lymphoma was synchronously systemic, with involvement of the lung, stomach and duodenum.
  • [MeSH-major] Adenocarcinoma / diagnosis. Duodenal Neoplasms / diagnosis. Lung Neoplasms / diagnosis. Lymphoma, B-Cell, Marginal Zone / diagnosis. Neoplasms, Multiple Primary / diagnosis. Stomach Neoplasms / diagnosis

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  • (PMID = 20437878.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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69. Ke B, Liang H, Zhang RP, Wang XJ, Wang G, Zhao JZ: [Prognostic analysis on primary duodenal adenocarcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2010 May;13(5):357-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prognostic analysis on primary duodenal adenocarcinoma].
  • OBJECTIVE: To investigate the prognostic factors of primary duodenal adenocarcinoma.
  • METHODS: The medical records of 67 patients with primary duodenal adenocarcinoma treated in our hospital from January 1990 to December 2005 were retrospectively analyzed.
  • [MeSH-major] Adenocarcinoma / diagnosis. Duodenal Neoplasms / diagnosis

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  • (PMID = 20499305.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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70. Li Y, Wo JM, Su RR, Ray MB, Martin RC: Alterations in manganese superoxide dismutase expression in the progression from reflux esophagitis to esophageal adenocarcinoma. Ann Surg Oncol; 2007 Jul;14(7):2045-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Alterations in manganese superoxide dismutase expression in the progression from reflux esophagitis to esophageal adenocarcinoma.
  • BACKGROUND: Comprehensive understanding of the basic mechanisms in the progression of esophagitis, Barrett esophagus (BE), and esophageal adenocarcinoma (EAC) is urgently needed to develop a management strategy for an effective screening of BE and management of EAC.
  • [MeSH-major] Adenocarcinoma / metabolism. Barrett Esophagus / metabolism. Esophageal Neoplasms / metabolism. Esophagitis, Peptic / metabolism. Superoxide Dismutase / biosynthesis
  • [MeSH-minor] Anastomosis, Surgical. Animals. Apoptosis. Cell Proliferation. Deoxyguanosine / analogs & derivatives. Deoxyguanosine / biosynthesis. Disease Models, Animal. Disease Progression. Duodenum / surgery. Epithelial Cells / metabolism. Esophagus / surgery. Immunohistochemistry. Oxidative Stress. Precancerous Conditions / metabolism. Rats. Rats, Sprague-Dawley

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  • (PMID = 17473952.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 88847-89-6 / 8-oxo-7-hydrodeoxyguanosine; EC 1.15.1.1 / Superoxide Dismutase; G9481N71RO / Deoxyguanosine
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71. Ueda J, Aimoto T, Nakamura Y, Hiroi M, Yamahatsu K, Hayakawa T, Naito Z, Uchida E: [Pancreaticoduodenal lymph node metastasis of neuroendocrine carcinoma of unknown primary associated with duodenal carcinoma]. Nihon Shokakibyo Gakkai Zasshi; 2010 Dec;107(12):1941-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pancreaticoduodenal lymph node metastasis of neuroendocrine carcinoma of unknown primary associated with duodenal carcinoma].
  • Duodenoscopy showed a hemorrhagic ulceration in the duodenum on the side opposite to the papilla of Vater.
  • Abdominal CT demonstrated a well-defined hypervascular mass, adjacent to the lesion of the duodenum.
  • Although as duodenal GIST was diagnosed, histologic examination for frozen sections during the procedure revealed tubular adenocarcinoma of the duodenum and pancreaticoduodenal lymph node metastasis of neuroendocrine carcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Carcinoma, Neuroendocrine / secondary. Duodenal Neoplasms / pathology. Neoplasms, Unknown Primary
  • [MeSH-minor] Aged. Duodenum / pathology. Humans. Lymphatic Metastasis. Male. Pancreas / pathology. Pancreaticoduodenectomy

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  • (PMID = 21139363.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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72. de Castro SM, van Eijck CH, Rutten JP, Dejong CH, van Goor H, Busch OR, Gouma DJ: Pancreas-preserving total duodenectomy versus standard pancreatoduodenectomy for patients with familial adenomatous polyposis and polyps in the duodenum. Br J Surg; 2008 Nov;95(11):1380-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pancreas-preserving total duodenectomy versus standard pancreatoduodenectomy for patients with familial adenomatous polyposis and polyps in the duodenum.
  • METHODS: All 26 patients who underwent PPTD for FAP in four centres in the Netherlands between January 2000 and January 2007 were compared with a group of 77 patients who had PD for ampulla of Vater adenocarcinoma at one centre during the same interval.
  • RESULTS: Morbidity rates were similar after PPTD for FAP (16 patients, 62 per cent) and PD for ampulla of Vater adenocarcinoma (44 patients, 57 per cent) (P = 0.694).
  • [MeSH-major] Adenocarcinoma / surgery. Adenomatous Polyposis Coli / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Pancreas / surgery. Pancreaticoduodenectomy / methods

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  • [Copyright] Copyright (c) 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
  • (PMID = 18844249.001).
  • [ISSN] 1365-2168
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] England
  • [Number-of-references] 43
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73. Lee HG, You DD, Paik KY, Heo JS, Choi SH, Choi DW: Prognostic factors for primary duodenal adenocarcinoma. World J Surg; 2008 Oct;32(10):2246-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic factors for primary duodenal adenocarcinoma.
  • BACKGROUND: The aim of this study was to review the clinical features of primary duodenal adenocarcinoma (PDA) patients and to identify factors that influence survival.
  • [MeSH-major] Adenocarcinoma / mortality. Duodenal Neoplasms / mortality
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Multivariate Analysis. Neoplasm Staging. Prognosis. Survival Rate. Treatment Outcome

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  • (PMID = 18668288.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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74. Hao Y, Triadafilopoulos G, Sahbaie P, Young HS, Omary MB, Lowe AW: Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma. Gastroenterology; 2006 Sep;131(3):925-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma.
  • BACKGROUND & AIMS: Barrett's esophagus is a precursor of esophageal adenocarcinoma.
  • DNA microarrays that enable a genome-wide assessment of gene expression enhance the identification of specific genes as well as gene expression patterns that are expressed by Barrett's esophagus and adenocarcinoma compared with normal tissues.
  • Barrett's esophagus length has also been identified as a risk factor for progression to adenocarcinoma, but whether there are intrinsic biological differences between short-segment and long-segment Barrett's esophagus can be explored with microarrays.
  • METHODS: Gene expression profiles for endoscopically obtained biopsy specimens of Barrett's esophagus or esophageal adenocarcinoma and associated normal esophagus and duodenum were identified for 17 patients using DNA microarrays.
  • Barrett's esophagus and esophageal adenocarcinoma express a unique set of stromal genes that is distinct from normal tissues but similar to other cancers.
  • Adenocarcinoma also showed lower and higher expression for many genes compared with Barrett's esophagus.
  • Stromal gene expression in Barrett's esophagus and adenocarcinoma is similar, indicating that these changes precede malignant transformation.

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  • (PMID = 16952561.001).
  • [ISSN] 0016-5085
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / P30 DK056339; United States / NIDDK NIH HHS / DK / R01 DK063624; United States / NIDDK NIH HHS / DK / P30 DK56339; United States / NIDDK NIH HHS / DK / R01 DK 063624
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Adhesion Molecules; 0 / Chondroitin Sulfate Proteoglycans; 0 / Cspg2 protein, mouse; 0 / DNA, Neoplasm; 0 / Lectins, C-Type; 0 / POSTN protein, human; 0 / VCAN protein, human; 126968-45-4 / Versicans; 9007-34-5 / Collagen
  • [Other-IDs] NLM/ NIHMS12359; NLM/ PMC2575112
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75. Sasaki S, Hatanaka K, Sahara N, Uekusa T, Hirayama K, Shirahata A, Ishimaru M: Collision tumor of primary malignant lymphoma and adenocarcinoma in the colon: report of a case. Surg Today; 2010 Oct;40(10):975-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Collision tumor of primary malignant lymphoma and adenocarcinoma in the colon: report of a case.
  • This report presents the case of a 62-year-old man with a collision tumor of primary malignant lymphoma and adenocarcinoma in the cecum.
  • Malignant lymphoma was also seen in the duodenum.
  • Systemic chemotherapy was administered for the malignant lymphoma, and a complete response was thus obtained.
  • However, just after chemotherapy multiple liver metastases of adenocarcinoma emerged, and chemotherapy against adenocarcinoma was therefore continued.
  • The occurrence of synchronous lymphoma and adenocarcinoma of the colorectum is rare.
  • [MeSH-major] Adenocarcinoma / diagnosis. Cecal Neoplasms / diagnosis. Duodenal Neoplasms / diagnosis. Lymphoma, B-Cell / diagnosis. Lymphoma, Follicular / diagnosis. Neoplasms, Multiple Primary / diagnosis
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Biopsy, Needle. Colectomy / methods. Colonoscopy. Humans. Male. Middle Aged. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 20872204.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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76. Halfdanarson TR, McWilliams RR, Donohue JH, Quevedo JF: A single-institution experience with 491 cases of small bowel adenocarcinoma. Am J Surg; 2010 Jun;199(6):797-803
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A single-institution experience with 491 cases of small bowel adenocarcinoma.
  • BACKGROUND: The optimal treatment of small bowel adenocarcinoma is unknown.
  • METHODS: The records of 491 patients with small bowel adenocarcinoma diagnosis between 1970 and 2005 were reviewed for patient and tumor characteristics, treatment effects, and survival.
  • RESULTS: The median age at diagnosis was 62 years.
  • The most common tumor locations were the duodenum (57%), jejunum (29%), and ileum (10%).
  • CONCLUSIONS: The prognosis of patients with small bowel adenocarcinoma is poor.
  • [MeSH-major] Adenocarcinoma / surgery. Intestinal Neoplasms / surgery. Intestine, Small
  • [MeSH-minor] Adult. Age Factors. Aged. Aged, 80 and over. Chi-Square Distribution. Female. Humans. Male. Middle Aged. Neoplasm Staging. Neoplasm, Residual. Prognosis. Proportional Hazards Models. Risk Factors. Sex Factors. Statistics, Nonparametric. Survival Rate. Treatment Outcome

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  • [Copyright] Published by Elsevier Inc.
  • (PMID = 20609724.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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77. Overman MJ, Kopetz S, Lin E, Abbruzzese JL, Wolff RA: Is there a role for adjuvant therapy in resected adenocarcinoma of the small intestine. Acta Oncol; 2010 May;49(4):474-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is there a role for adjuvant therapy in resected adenocarcinoma of the small intestine.
  • BACKGROUND: The benefit of adjuvant therapy for resected small bowel adenocarcinoma has not been proven.
  • We undertook a retrospective analysis to evaluate the benefit of adjuvant therapy in a clearly defined patient population with curatively resected small bowel adenocarcinoma.
  • MATERIAL AND METHODS: We identified 54 patients with small bowel adenocarcinoma who underwent margin-negative surgical resection and were evaluated after surgery at the University of Texas, M. D.
  • RESULTS: Median age was 55 years and primary tumor site was duodenum in 67%, jejunum in 20%, and ileum in 13%.
  • DISCUSSION: The use of adjuvant therapy for curatively resected small bowel adenocarcinoma was associated with an improvement in DFS.
  • [MeSH-major] Adenocarcinoma / therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Intestinal Neoplasms / therapy. Intestine, Small
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Chemotherapy, Adjuvant. Disease-Free Survival. Duodenal Neoplasms / therapy. Female. Follow-Up Studies. Humans. Ileal Neoplasms / therapy. Jejunal Neoplasms / therapy. Kaplan-Meier Estimate. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Proportional Hazards Models. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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  • (PMID = 20397775.001).
  • [ISSN] 1651-226X
  • [Journal-full-title] Acta oncologica (Stockholm, Sweden)
  • [ISO-abbreviation] Acta Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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78. Chang HK, Yu E, Kim J, Bae YK, Jang KT, Jung ES, Yoon GS, Kim JM, Oh YH, Bae HI, Kim GI, Jung SJ, Gu MJ, Kim JY, Jang KY, Jun SY, Eom DW, Kwon KW, Kang GH, Park JB, Hong S, Lee JS, Park JY, Hong SM, Korean Small Intestinal Cancer Study Group: Adenocarcinoma of the small intestine: a multi-institutional study of 197 surgically resected cases. Hum Pathol; 2010 Aug;41(8):1087-96
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  • [Title] Adenocarcinoma of the small intestine: a multi-institutional study of 197 surgically resected cases.
  • Small intestinal adenocarcinoma is a rare malignant neoplasm, and its clinicopathologic characteristics have not been well elucidated.
  • A total of 197 small intestinal adenocarcinoma cases were collected from 22 institutions in South Korea and were evaluated for clinicopathologic factors that affect the prognosis of small intestinal adenocarcinoma patients using univariate and multivariate analyses.
  • Tumors were located in the duodenum of 108 cases (55%), the jejunum in 59 (30%), and the ileum in 30 (15%).
  • Synchronous or metachronous malignant tumors were identified in 31 cases (16%), including 13 colorectal and 10 stomach cancers.
  • The median survival time for all small intestinal adenocarcinoma patients was 39.7 months.
  • Compared with small intestinal adenocarcinomas without accompanying sporadic adenomas, small intestinal adenocarcinomas with accompanying adenomas were more well differentiated (P < .0001), with a more polypoid growth pattern (P < .0001), a lower pT classification (P < .0001), less perineural invasion (P = .01), and less lymphatic invasion (P = .03).
  • Small intestinal adenocarcinoma patients with associated sporadic adenomas (77%) had a significantly better 5-year survival rate than those without sporadic adenomas (38%, P = .02).
  • By univariate analysis, small intestinal adenocarcinoma patients had significantly different survival based on pT classification (P = .003), lymph node metastasis (P < .0001), distal location (jejunal and ileal carcinomas) (P = .003), retroperitoneal tumor seeding (P < .0001), vascular invasion (P = .007), lymphatic invasion (P = .001), peritumoral dysplasia (P = .004), and radiation therapy (P = .006).
  • In conclusion, (1) small intestinal adenocarcinomas are diagnosed at an advanced disease stage; therefore, the development of strategies for detection at an earlier stage is needed. (2) Small intestinal adenocarcinoma patients with an adenomatous component had a better survival than those without an adenomatous component. (3) Lymph node metastasis and distal location (jejunum and ileum) of tumor are the most important independent prognostic factors.
  • [MeSH-major] Adenocarcinoma / pathology. Duodenal Neoplasms / pathology. Ileal Neoplasms / pathology. Jejunal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Intestine, Small / pathology. Kaplan-Meier Estimate. Lymphatic Metastasis / pathology. Male. Middle Aged. Prognosis

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20334897.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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79. Hiki N, Fukunaga T, Tokunaga M, Ohyama S, Yamada K, Saiura A, Yamaguchi T: An effective duodenum bulb mobilization for extracorporeal Billroth I anastomosis of laparoscopic gastrectomy. J Gastrointest Surg; 2009 Feb;13(2):230-5
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  • [Title] An effective duodenum bulb mobilization for extracorporeal Billroth I anastomosis of laparoscopic gastrectomy.
  • BACKGROUND DATA: Extracorporeal circular-stapled Billroth I (B-I) anastomosis is difficult in patients with obesity, a large body shape, or small remnant stomach, as it requires the duodenal stump to be lifted outside of the wound.
  • The aim of this study was to evaluate the feasibility of circular-stapled B-I reconstruction for laparoscopy-assisted distal gastrectomy (LADG) with effective duodenal mobilization.
  • The greater omentum, comprised of four membrane layers, was completely dissected for effective duodenal bulb mobilization to allow easy performance of extracorporeal end-to-end gastroduodenostomy.
  • CONCLUSIONS: Feasible duodenal bulb mobilization by complete dissection of the greater omentum allows easy performance of extracorporeal B-I anastomosis and minimizes complications related to anastomosis in LADG.
  • [MeSH-major] Adenocarcinoma / surgery. Gastrectomy. Gastroenterostomy / methods. Laparoscopy. Stomach Neoplasms / surgery. Surgical Stapling / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Body Mass Index. Cohort Studies. Duodenum / surgery. Feasibility Studies. Female. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 18795375.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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80. Moon YW, Rha SY, Shin SJ, Chang H, Shim HS, Roh JK: Adenocarcinoma of the small bowel at a single Korean institute: management and prognosticators. J Cancer Res Clin Oncol; 2010 Mar;136(3):387-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of the small bowel at a single Korean institute: management and prognosticators.
  • PURPOSE: Small bowel adenocarcinoma (SBA) is a rare malignancy with a poor outcome.
  • RESULTS: The most common primary tumor site was the duodenum (82%).
  • CONCLUSIONS: Early diagnosis is crucial to improve outcomes of SBA with respect to increasing resectability.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Intestinal Neoplasms / diagnosis. Intestinal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Algorithms. Chemotherapy, Adjuvant / methods. Chemotherapy, Adjuvant / utilization. Digestive System Surgical Procedures / methods. Female. Humans. Intestine, Small / pathology. Korea. Male. Middle Aged. Prognosis. Recurrence. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 19760196.001).
  • [ISSN] 1432-1335
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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81. Inoue Y, Hayashi M, Arisaka Y, Higuchi K, Egashira Y, Tanigawa N: Adenocarcinoma arising in a heterotopic pancreas (Heinrich type III): a case report. J Med Case Rep; 2010;4:39

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma arising in a heterotopic pancreas (Heinrich type III): a case report.
  • INTRODUCTION: Heterotopic pancreatic cancer in the duodenum is a very rare disease.
  • We report a rare case of malignant transformation of heterotopic pancreas (Heinrich type III) in the duodenum with long-term survival of the patient, and review the 12 cases in the literature.
  • Endoscopy and upper gastrointestinal contrast study showed marked duodenal stenosis.
  • Histopathological examination of the surgically resected specimen showed malignant transformation of heterotopic pancreas (Heinrich type III) in the duodenum.
  • CONCLUSION: Adenocarcinoma arising within the heterotopic pancreas appears to be rare.
  • It is difficult to obtain a correct diagnosis preoperatively.
  • When the patient is symptomatic or there is a suspicion of malignancy, surgical management with intra-operative frozen section diagnosis is indicated.

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  • [Cites] Br Med J. 1967 Sep 30;3(5569):843 [6036437.001]
  • [Cites] Arch Surg. 1983 Aug;118(8):979-80 [6870529.001]
  • [Cites] Pancreas. 2007 Jan;34(1):152-6 [17198198.001]
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  • (PMID = 20205891.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2827432
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82. Zhang T, Zhang F, Han Y, Gu Z, Zhou Y, Cheng Q, Zhu Y, Zhang C, Wang Y: A rat surgical model of esophageal metaplasia and adenocarcinoma-induced by mixed reflux of gastric acid and duodenal contents. Dig Dis Sci; 2007 Nov;52(11):3202-8
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  • [Title] A rat surgical model of esophageal metaplasia and adenocarcinoma-induced by mixed reflux of gastric acid and duodenal contents.
  • Recent clinical data have revealed that mixed reflux (MR) of gastric acid and duodenal contents frequently occurs in patients with gastroesophageal reflux disease and a progressive increase of MR occurs with increasing severity across gastroesophageal reflux disease.
  • Herein we report a novel rat surgical model in which esophageal metaplasia and adenocarcinoma develop as complications of MR.
  • Severe inflammatory and proliferative changes, high prevalence of esophageal metaplasia (78%), and adenocarcinoma (50%) were observed in the lower part of the esophagus of rats 20 weeks after surgery.
  • The resulting esophageal lesions resembled those described in humans and supported a progression from intestinal metaplasia to dysplasia and, ultimately, esophageal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenostomy / methods. Esophageal Neoplasms / surgery. Esophagostomy / methods. Esophagus / pathology. Gastroesophageal Reflux / complications. Jejunostomy / methods
  • [MeSH-minor] Animals. Disease Models, Animal. Disease Progression. Duodenum / secretion. Gastric Acid / secretion. Male. Metaplasia / etiology. Metaplasia / pathology. Metaplasia / surgery. Models, Anatomic. Rats. Rats, Sprague-Dawley

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  • (PMID = 17393326.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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83. Uvarov IB, Genrikh SR, Liutov DA, Shatov MN, Onopriev VI: [Primary jejunogastroplasty with end-loop gastroenteroanastomosis and inclusion of the duodenum in distal resection of the stomach (surgical technology and functional results)]. Vestn Khir Im I I Grek; 2008;167(1):37-42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary jejunogastroplasty with end-loop gastroenteroanastomosis and inclusion of the duodenum in distal resection of the stomach (surgical technology and functional results)].
  • Complex examination of 57 patients (25 patients of the main group, and 32 controls) has shown that the proposed technology of primary JGP can reliably prevent gastroesophageal and duodeno-enterogastic reflux, creates conditions for the portion-rhythmical evacuation of food from the gastric stump.
  • [MeSH-major] Anastomosis, Roux-en-Y / methods. Duodenum / surgery. Gastroplasty. Jejunum / surgery. Stomach / surgery
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / surgery. Adult. Aged. Female. Gastrointestinal Neoplasms / epidemiology. Gastrointestinal Neoplasms / surgery. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 18411666.001).
  • [ISSN] 0042-4625
  • [Journal-full-title] Vestnik khirurgii imeni I. I. Grekova
  • [ISO-abbreviation] Vestn. Khir. Im. I. I. Grek.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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84. Overman MJ, Kopetz S, Wen S, Hoff PM, Fogelman D, Morris J, Abbruzzese JL, Ajani JA, Wolff RA: Chemotherapy with 5-fluorouracil and a platinum compound improves outcomes in metastatic small bowel adenocarcinoma. Cancer; 2008 Oct 15;113(8):2038-45
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chemotherapy with 5-fluorouracil and a platinum compound improves outcomes in metastatic small bowel adenocarcinoma.
  • BACKGROUND: Metastatic small bowel adenocarcinoma (SBA) has a poor prognosis.
  • The primary tumor site was the jejunum in 35 patients (43%), duodenum in 30 patients (38%), ileum in 6 patients (8%), and nonspecified small bowel in 9 patients (11%).
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Intestinal Neoplasms / drug therapy. Intestine, Small / pathology
  • [MeSH-minor] Adult. Aged. Disease-Free Survival. Female. Fluorouracil / administration & dosage. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Recurrence, Local / drug therapy. Platinum Compounds / administration & dosage. Retrospective Studies

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  • [Copyright] (c) 2008 American Cancer Society.
  • (PMID = 18759326.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Platinum Compounds; U3P01618RT / Fluorouracil
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85. Mhanna T, Ranchere-Vince D, Hervieu V, Tardieu D, Scoazec JY, Partensky C: Clear cell myomelanocytic tumor (PEComa) of the duodenum in a child with a history of neuroblastoma. Arch Pathol Lab Med; 2005 Nov;129(11):1484-6
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  • [Title] Clear cell myomelanocytic tumor (PEComa) of the duodenum in a child with a history of neuroblastoma.
  • The lesion, located in the duodenal wall, was diagnosed in a child with a history of cervical neuroblastoma that was in remission after surgical resection and chemotherapy.
  • The diagnosis was obtained by examination of a biopsy specimen taken during laparoscopy.
  • Examination of the surgical specimen confirmed the diagnosis of PEComa.
  • [MeSH-major] Duodenal Neoplasms / pathology. Epithelioid Cells / pathology. Melanocytes / pathology. Neuroblastoma / pathology. Smooth Muscle Tumor / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Biomarkers, Tumor / analysis. Child. Diagnosis, Differential. Endocrine Gland Neoplasms / diagnosis. Humans. Male. Neoplasms, Second Primary. Pancreaticoduodenectomy. Sarcoma, Clear Cell / diagnosis. Treatment Outcome

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  • (PMID = 16253032.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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86. Riall TS, Cameron JL, Lillemoe KD, Campbell KA, Sauter PK, Coleman J, Abrams RA, Laheru D, Hruban RH, Yeo CJ: Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survival. J Gastrointest Surg; 2005 Dec;9(9):1191-204; discussion 1204-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survival.
  • The study objective was to update the survival analysis at the 5-year mark of patients undergoing standard versus radical (extended) pancreaticoduodenectomy (PD) for periampullary adenocarcinoma (cancers of the pancreas, ampulla, common bile duct, and duodenum).
  • Five patients were excluded from final analysis because final pathology failed to reveal adenocarcinoma.
  • For pancreatic adenocarcinoma patients, the 1- and 5-year survival rates in the standard group were 75% and 13%, respectively, compared with 73% and 29% in the radical group (P = 0.13).
  • The increased morbidity rate, longer operative time, and similar survival for radical PD led us to conclude that pylorus-preserving PD without retroperitoneal lymphadenectomy should be the procedure of choice for most patients with resectable periampullary adenocarcinoma.
  • While there is an intriguing trend toward improved survival in patients with pancreatic adenocarcinoma in the radical group, this trend may be largely accounted for by the higher incidence of microscopically margin positive resections in the standard resection group (21%) compared with a 5% incidence in the radical group (P = 0.002).
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Gastrectomy / methods. Lymph Node Excision / methods. Pancreaticoduodenectomy / methods

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  • (PMID = 16332474.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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87. Bucher P, Gervaz P, Morel P: Long-term results of radical resection for locally advanced duodenal adenocarcinoma. Hepatogastroenterology; 2005 Nov-Dec;52(66):1727-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term results of radical resection for locally advanced duodenal adenocarcinoma.
  • BACKGROUND/AIMS: Duodenal adenocarcinomas are uncommon tumors characterized by non-specific symptoms and late diagnosis.
  • The objective of this study was to assess long-term results of locally advanced duodenal adenocarcinoma treated by surgical resection.
  • METHODOLOGY: A retrospective study, over a 10-year period, identified 9 patients (mean age 65 years) treated for duodenal carcinoma.
  • RESULTS: Out of nine patients who were treated for duodenal adenocarcinoma, 8 underwent R0 resection (5 pancreaticoduodenectomies, 1 total pancreaticoduodenectomy and 2 segmental duodenal resections).
  • CONCLUSIONS: Radical surgical resection for locally advanced duodenal adenocarcinomas provides good long-term results in terms of patient survival, even for N1 tumors (stage III).
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Duodenal Neoplasms / pathology. Duodenal Neoplasms / surgery. Lymph Nodes / pathology. Pancreaticoduodenectomy / methods
  • [MeSH-minor] Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Retrospective Studies. Risk Assessment. Sigmoidoscopy / methods. Survival Analysis. Time Factors. Treatment Outcome

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  • (PMID = 16334766.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Greece
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88. Struck A, Howard T, Chiorean EG, Clarke JM, Riffenburgh R, Cardenes HR: Non-ampullary duodenal adenocarcinoma: factors important for relapse and survival. J Surg Oncol; 2009 Aug 1;100(2):144-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-ampullary duodenal adenocarcinoma: factors important for relapse and survival.
  • BACKGROUND: Duodenal adenocarcinoma (DA) is rare, but potentially curable.
  • Median survival from diagnosis was 27.5 months (0.5-226.7 months).
  • [MeSH-major] Adenocarcinoma / mortality. Duodenal Neoplasms / mortality. Neoplasm Recurrence, Local / etiology

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  • [ErratumIn] J Surg Oncol. 2009 Oct 1;100(5):434
  • (PMID = 19544358.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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89. Chen KH, Mukaisho K, Sugihara H, Araki Y, Yamamoto G, Hattori T: High animal-fat intake changes the bile-acid composition of bile juice and enhances the development of Barrett's esophagus and esophageal adenocarcinoma in a rat duodenal-contents reflux model. Cancer Sci; 2007 Nov;98(11):1683-8
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  • [Title] High animal-fat intake changes the bile-acid composition of bile juice and enhances the development of Barrett's esophagus and esophageal adenocarcinoma in a rat duodenal-contents reflux model.
  • The dietary components responsible for the development of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) remain unclear.
  • Because only high cow-fat intake induced changes in the composition of bile acids in bile juice, we then selected animals fed with a low soybean-oil diet and those with a high cow-fat diet to carry out esophago-jejunostomy for reflux of the duodenal contents, and compared sequential morphological changes between these groups up to 30 weeks after surgery.
  • [MeSH-major] Adenocarcinoma / pathology. Barrett Esophagus / pathology. Bile / secretion. Bile Acids and Salts / chemistry. Dietary Fats / adverse effects. Duodenogastric Reflux / pathology. Duodenum / pathology. Esophageal Neoplasms / pathology. Gastrointestinal Contents / chemistry

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  • (PMID = 17868414.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bile Acids and Salts; 0 / Dietary Fats
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90. Hurtuk MG, Devata S, Brown KM, Oshima K, Aranha GV, Pickleman J, Shoup M: Should all patients with duodenal adenocarcinoma be considered for aggressive surgical resection? Am J Surg; 2007 Mar;193(3):319-24; discussion 324-5
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  • [Title] Should all patients with duodenal adenocarcinoma be considered for aggressive surgical resection?
  • BACKGROUND: Long-term survival for duodenal adenocarcinoma is inconsistent in the literature, and the biology of duodenal adenocarcinoma is poorly understood.
  • METHODS: One institution's experience with duodenal adenocarcinoma from 1984 to 2005 is reviewed.
  • CONCLUSIONS: Clinicopathologic factors important to survival in duodenal cancer are T4 tumor status and tumor size.
  • The biology of this cancer is poorly understood; therefore, aggressive resection for all duodenal adenocarcinomas is recommended for all patients medically fit to undergo resection.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery. Patient Selection

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  • (PMID = 17320527.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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91. Hung FC, Kuo CM, Chuah SK, Kuo CH, Chen YS, Lu SN, Chang Chien CS: Clinical analysis of primary duodenal adenocarcinoma: an 11-year experience. J Gastroenterol Hepatol; 2007 May;22(5):724-8
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  • [Title] Clinical analysis of primary duodenal adenocarcinoma: an 11-year experience.
  • BACKGROUND AND AIM: The impact of obstructive jaundice (OJ) complicated by primary duodenal adenocarcinoma (PDA) on survival, and its treatment options, has rarely been mentioned in literature.
  • METHODS: From May 1994 to February 2005, all duodenal malignancies treated at Kaohsiung Chang Gung Memorial Hospital were reviewed.
  • Preliminary findings were made on a total of 116 duodenal adenocarcinoma (DA) cases.
  • [MeSH-major] Adenocarcinoma / complications. Adenocarcinoma / mortality. Duodenal Neoplasms / complications. Duodenal Neoplasms / mortality. Jaundice, Obstructive / complications. Postoperative Complications / etiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Aspartate Aminotransferases / blood. Biliary Tract Surgical Procedures. Cell Differentiation. Databases as Topic. Digestive System Surgical Procedures. Drainage. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Lymph Nodes / pathology. Male. Middle Aged. Neoplasm Staging. Prognosis. Proportional Hazards Models. Retrospective Studies. Risk Assessment. Risk Factors. Smoking / adverse effects. Treatment Outcome

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  • (PMID = 17444863.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] EC 2.6.1.1 / Aspartate Aminotransferases
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92. Westgaard A, Larønningen S, Mellem C, Eide TJ, Clausen OP, Møller B, Gladhaug IP: Are survival predictions reliable? Hospital volume versus standardisation of histopathologic reporting for accuracy of survival estimates after pancreatoduodenectomy for adenocarcinoma. Eur J Cancer; 2009 Nov;45(16):2850-9
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  • [Title] Are survival predictions reliable? Hospital volume versus standardisation of histopathologic reporting for accuracy of survival estimates after pancreatoduodenectomy for adenocarcinoma.
  • Using population-based nationwide data from the Cancer Registry of Norway, we examined the influence on survival estimates of standardised histopathologic reporting versus non-standardised histopathologic reporting after pancreatoduodenectomy for adenocarcinomas in the pancreas, distal bile duct, ampulla and duodenum (n=506).
  • [MeSH-major] Adenocarcinoma / mortality. Pancreatic Neoplasms / mortality. Pancreaticoduodenectomy / mortality. Pathology, Clinical / standards

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  • (PMID = 19376696.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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93. Maire F, Hammel P, Ponsot P, Aubert A, O'Toole D, Hentic O, Levy P, Ruszniewski P: Long-term outcome of biliary and duodenal stents in palliative treatment of patients with unresectable adenocarcinoma of the head of pancreas. Am J Gastroenterol; 2006 Apr;101(4):735-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term outcome of biliary and duodenal stents in palliative treatment of patients with unresectable adenocarcinoma of the head of pancreas.
  • AIM: To evaluate the incidence of biliary and duodenal stenoses as well as technical success and short- and long-term patency of endoscopically deployed stents in patients with unresectable pancreatic cancer.
  • Patients with biliary and/or duodenal stenoses underwent endoscopic stent insertion as first intention therapy.
  • Biliary and duodenal stenoses occurred in 81 and 25 patients, respectively.
  • Duodenal stenting was successful in 24 patients (96%); among them, 96% required a single stent (median duration of stent patency 6 months [0.5-15.7]).
  • In the 23 patients who developed both biliary and duodenal stenoses, combined stenting was successful in 91% of cases.
  • CONCLUSION: Endoscopic palliative treatment of both biliary and duodenal stenoses is safe and effective in the long term, including in patients with combined obstructions.
  • [MeSH-major] Adenocarcinoma / complications. Biliary Tract. Cholestasis, Extrahepatic / therapy. Duodenal Obstruction / therapy. Duodenum. Palliative Care. Pancreatic Neoplasms / complications. Stents

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  • [CommentIn] Am J Gastroenterol. 2006 Apr;101(4):743-5 [16635222.001]
  • (PMID = 16635221.001).
  • [ISSN] 0002-9270
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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94. Brönnimann E, Potthast S, Vlajnic T, Oertli D, Heizmann O: Annular pancreas associated with duodenal carcinoma. World J Gastroenterol; 2010 Jul 7;16(25):3206-10
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  • [Title] Annular pancreas associated with duodenal carcinoma.
  • We report what is, to the best of our knowledge, the first case in the English literature of duodenal adenocarcinoma in a patient with AP.
  • In a 55-year old woman with duodenal outlet stenosis magnetic resonance cholangiopancreatography showed an aberrant pancreatic duct encircling the duodenum.
  • Duodenopancreatectomy revealed a duodenal adenocarcinoma, surrounded by an incomplete AP.
  • [MeSH-major] Adenocarcinoma / pathology. Duodenal Neoplasms / pathology. Pancreas / abnormalities
  • [MeSH-minor] Cholangiopancreatography, Magnetic Resonance. Duodenal Obstruction / etiology. Duodenal Obstruction / pathology. Duodenal Obstruction / surgery. Duodenum / pathology. Duodenum / surgery. Female. Humans. Jaundice, Obstructive / etiology. Jaundice, Obstructive / pathology. Jaundice, Obstructive / surgery. Middle Aged. Pancreaticoduodenectomy

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  • (PMID = 20593508.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
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95. Kalogerinis PT, Poulos JE, Morfesis A, Daniels A, Georgakila S, Daignualt T, Georgakilas AG: Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective. BMC Gastroenterol; 2010;10:109
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective.
  • BACKGROUND: There is very small occurrence of adenocarcinoma in the small bowel.
  • We present a case of primary duodenal adenocarcinoma and discuss the findings of the case diagnostic modalities, current knowledge on the molecular biology behind small bowel neoplasms and treatment options.
  • CASE: The patient had a history of iron deficiency anemia and occult bleeding with extensive workup consisting of upper endoscopy, colonoscopy, capsule endoscopy, upper gastrointestinal series with small bowel follow through and push enteroscopy.
  • Due to persistent abdominal pain and iron deficiency anemia the patient underwent push enteroscopy which revealed adenocarcinoma of the duodenum.
  • The patient underwent en-bloc duodenectomy which revealed T3N1M0 adenocarcinoma of the 4th portion of the duodenum.
  • CONCLUSIONS: Primary duodenal carcinoma, although rare should be considered in the differential diagnosis of occult gastrointestinal bleeding when evaluation of the lower and upper GI tract is unremarkable.
  • We discuss the current evaluation and management of this small bowel neoplasm.
  • [MeSH-major] Adenocarcinoma / diagnosis. Biomarkers, Tumor / analysis. Duodenal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Duodenoscopy. Female. Humans. Laparotomy. Ligaments. Tomography, X-Ray Computed

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  • (PMID = 20849628.001).
  • [ISSN] 1471-230X
  • [Journal-full-title] BMC gastroenterology
  • [ISO-abbreviation] BMC Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2949773
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96. Kang SM, Murata A, Tendou M, Tezuka K, Nishino Y: [A case report of primary duodenal adenocarcinoma with marked lymph node metastases responding to chemotherapy with S-1 plus CDDP combination]. Gan To Kagaku Ryoho; 2009 Sep;36(9):1569-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case report of primary duodenal adenocarcinoma with marked lymph node metastases responding to chemotherapy with S-1 plus CDDP combination].
  • The patient was a 48-year-old female who underwent combination chemotherapy of S-1 plus CDDP after diagnosis of primary duodenal adenocarcinoma with marked lymph node metastases.
  • This case suggests that the combination of S-1 and CDDP may be an effective regimen for advanced primary duodenal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Duodenal Neoplasms / drug therapy. Lymphatic Metastasis

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  • (PMID = 19755836.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents; 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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97. Yamasaki T, Nebiki H, Sasaki E, Kurai O: Successful treatment of duodenal adenocarcinoma with multiple liver metastases by S-1 + irinotecan (CPT-11). Clin J Gastroenterol; 2009 Aug;2(4):287-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful treatment of duodenal adenocarcinoma with multiple liver metastases by S-1 + irinotecan (CPT-11).
  • Unresectable duodenal adenocarcinoma excluding the ampullary region is rare, and no standard chemotherapy has been defined for this disease.
  • Although S-1-based chemotherapy is widely administered for advanced gastric cancer, few reports have described advanced duodenal cancer treated with S-1-based chemotherapy.
  • We present herein a case of duodenal adenocarcinoma with liver metastases.
  • Gastroduodenal endoscopy revealed an ulcerative lesion on the upper wall of the duodenal bulb, and biopsy specimens showed well-differentiated adenocarcinoma.
  • S-1-based regimens appear effective and well tolerated, and S-1 may thus represent a useful option for advanced duodenal cancer.

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  • (PMID = 26192427.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Chemotherapy / Duodenal cancer / Irinotecan / Liver metastases / S-1
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98. Iitaka D, Ikoma H, Kawaguchi T, Murayama Y, Komatsu S, Shiozaki A, Kuriu Y, Nakanishi M, Ichikawa D, Fujiwara H, Okamoto K, Ochiai T, Kokuba Y, Sonoyama T, Konishi H, Yoshikawa T, Otsuji E: [A case report--locally advanced pancreatic adenocarcinoma was resected after chemotherapy]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2358-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case report--locally advanced pancreatic adenocarcinoma was resected after chemotherapy].
  • Upper gastrointestinal endoscopy revealed circumferential stenosis in the fourth portion of the duodenum, while CT revealed a tumor with a diameter of 60 mm continuing as a single mass from the pancreatic body and tail to the fourth portion of the duodenum, and this was accompanied by findings that raised suspicions of circumferential invasion of the superior mesentric artery (SMA).
  • Based on these results and biopsy, the patient was diagnosed with pancreatic and SMA invasion of duodenal cancer that was considered to be unresectable.
  • In the surgical findings, the tumor continued as a single mass from the pancreatic body and tail to the third portion of the duodenum, and the surrounding area exhibited marked fibrosis.
  • We performed a pancreatic tail resection along with combined resection of third and fourth portions of the duodenum, transverse colon and splenic flexure, and left adrenal gland.
  • The case was diagnosed to be well-differentiated invasive ductal pancreatic cancer with duodenal invasion.
  • In this case, the treatment was initially started by considering the case as one of duodenal cancer, but the final results of a pathological diagnosis revealed that it was pancreatic cancer.
  • However, either way, even though the case was unresectable before the chemotherapy performed for duodenal cancer was significantly effective for the pancreatic cancer.
  • [MeSH-major] Adenocarcinoma / therapy. Pancreatic Neoplasms / therapy
  • [MeSH-minor] Adult. Antimetabolites, Antineoplastic / administration & dosage. Antineoplastic Agents / administration & dosage. Cisplatin / administration & dosage. Combined Modality Therapy. Drug Combinations. Duodenal Neoplasms / pathology. Duodenal Neoplasms / therapy. Humans. Male. Mesenteric Artery, Superior / pathology. Neoplasm Invasiveness. Oxonic Acid / administration & dosage. Taxoids / administration & dosage. Tegafur / administration & dosage

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  • (PMID = 21224572.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents; 0 / Drug Combinations; 0 / Taxoids; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 15H5577CQD / docetaxel; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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99. Birbe R, Palazzo JP, Walters R, Weinberg D, Schulz S, Waldman SA: Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract. Hum Pathol; 2005 Feb;36(2):170-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract.
  • Guanylyl cyclase C protein was expressed by epithelial cells from the duodenum to the rectum, but not by those in normal esophagus and stomach.
  • [MeSH-major] Adenocarcinoma / enzymology. Gastrointestinal Neoplasms / enzymology. Gastrointestinal Tract / enzymology. Guanylate Cyclase / metabolism. Metaplasia / enzymology. Receptors, Peptide / metabolism
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Humans. Immunoenzyme Techniques. Intestinal Mucosa / enzymology. Intestinal Mucosa / pathology. RNA, Messenger / metabolism. RNA, Neoplasm / analysis. Receptors, Guanylate Cyclase-Coupled. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 15754294.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA75123; United States / NCI NIH HHS / CA / CA79663; United States / NCI NIH HHS / CA / CA95026; United States / NCI NIH HHS / CA / R01 CA075123-06; United States / NIGMS NIH HHS / GM / R01 GM050290-05
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Receptors, Peptide; EC 4.6.1.2 / Guanylate Cyclase; EC 4.6.1.2 / Receptors, Guanylate Cyclase-Coupled; EC 4.6.1.2 / enterotoxin receptor
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100. Gold JS, Tang LH, Gönen M, Coit DG, Brennan MF, Allen PJ: Utility of a prognostic nomogram designed for gastric cancer in predicting outcome of patients with R0 resected duodenal adenocarcinoma. Ann Surg Oncol; 2007 Nov;14(11):3159-67
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Utility of a prognostic nomogram designed for gastric cancer in predicting outcome of patients with R0 resected duodenal adenocarcinoma.
  • BACKGROUND: There is little information to determine prognosis or to guide clinical care for patients with duodenal adenocarcinoma.
  • We have hypothesized that survival following resection of duodenal cancer is similar to survival following resection of distal gastric cancer.
  • We tested the utility of a nomogram created for determining disease-specific survival (DSS) after R0 resection of gastric cancer in estimating DSS for patients with resected duodenal cancer.
  • METHODS: Review of a prospective database identified 106 patients who underwent R0 resection of duodenal cancer.
  • RESULTS: Duodenal cancers were more deeply invasive than gastric cancer (P < .01).
  • Younger age (P = .002), negative regional lymph nodes (P = .03), and tumors confined to the bowel wall or subserosa (P = .03) were associated with improved DSS for duodenal cancer.
  • When applied to patients with duodenal cancer, the nomogram had a concordance probability of 0.70, and calibration appeared to be accurate.
  • CONCLUSIONS: A nomogram created for determining DSS after resection of gastric cancer predicts outcome for duodenal cancer patients and may prove to be useful for research and in guiding clinical care.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery. Nomograms. Stomach Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Lymph Nodes / pathology. Lymphatic Metastasis. Male. Middle Aged. Models, Statistical. Neoplasm Invasiveness. Neoplasm Staging. Pancreaticoduodenectomy. Prognosis. Prospective Studies. Risk Factors. Survival Rate

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  • (PMID = 17680313.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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