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1. Ferrando Marco J, Pallas Regueira A, Moro Valdezate D, Fernández Martínez C: [Collision tumor of the ampulla of Vater: carcinoid and adenocarcinoma]. Rev Esp Enferm Dig; 2007 Apr;99(4):235-8
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  • [Title] [Collision tumor of the ampulla of Vater: carcinoid and adenocarcinoma].
  • We report the case of a periampullary collision tumor, in which a duodenal-wall carcinoid and an adenocarcinoma of the head of the pancreas coexisted.
  • Solid cords and nests of neuroendocrine cells in the duodenal wall formed the carcinoid tumor, whereas the other neoplasm was made up of a well-differentiated adenocarcinoma of the pancreas.
  • [MeSH-major] Adenocarcinoma / pathology. Ampulla of Vater. Carcinoid Tumor / pathology. Common Bile Duct Neoplasms / pathology. Duodenal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 17590108.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 15
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2. Ishibashi Y, Ito Y, Omori K, Wakabayashi K: Signet ring cell carcinoma of the ampulla of vater. A case report. JOP; 2009;10(6):690-3
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  • [Title] Signet ring cell carcinoma of the ampulla of vater. A case report.
  • CONTEXT: Signet ring cell carcinoma of the ampulla of Vater is extremely rare and only 12 cases have previously been described in the English language literature.
  • We report a case of advanced signet ring cell carcinoma of the ampulla of Vater, with invasion of the duodenum and pancreas.
  • Duodenoscopy indicated an irregularly shaped erosion on the ampulla of Vater.
  • Histological examination of a biopsy revealed adenocarcinoma.
  • The diagnosis was carcinoma of the ampulla of Vater, and a pancreaticoduodenectomy was performed.
  • [MeSH-major] Ampulla of Vater. Carcinoma, Signet Ring Cell / diagnosis. Common Bile Duct Neoplasms / diagnosis

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  • (PMID = 19890196.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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3. Corbo V, Ritelli R, Barbi S, Funel N, Campani D, Bardelli A, Scarpa A: Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas. PLoS One; 2010;5(9):e12653
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  • [Title] Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas.
  • Tumours of the pancreas are aggressive neoplasms for which no effective therapeutic strategy is currently available.
  • METHODOLOGY/PRINCIPAL FINDINGS: We conducted a DNA-sequence analysis of a selected set of 35 kinase genes in a panel of 52 pancreatic exocrine neoplasms, including 36 pancreatic ductal adenocarcinoma, and 16 ampulla of Vater cancer.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Ampulla of Vater / enzymology. Base Sequence. Cell Line, Tumor. Female. Humans. Male. Middle Aged. Molecular Sequence Data


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4. Stipa F, Alessandroni L, Cimitan A, Burza A, Cavallotti C, Cavallini M, Tersigni R, Ziparo V: [Pancreaticoduodenectomy for adenocarcinoma of the pancreatic head and papilla of Vater]. Minerva Chir; 2009 Aug;64(4):395-406
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  • [Title] [Pancreaticoduodenectomy for adenocarcinoma of the pancreatic head and papilla of Vater].
  • [Transliterated title] Duodenocefalopancreatectomia per adenocarcinoma della testa del pancreas e della papilla di Vater.
  • AIM: The authors report their consecutive experience in the surgical management of adenocarcinoma (ADC) of head of pancreas and papilla of Vater, in order to review the available literature.
  • METHODS: One hundred and seventy cases (131 in the head of pancreas and 39 in the papilla of Vater) were operated upon for ADC by radical pancreaticoduodenectomy in the period 1972-2005.
  • In ADC of the papilla of Vater, for the same stages, the 5-year survival rates were 54.4%, 51.4%, 0% and 37.5%, respectively.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy

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  • (PMID = 19648859.001).
  • [ISSN] 0026-4733
  • [Journal-full-title] Minerva chirurgica
  • [ISO-abbreviation] Minerva Chir
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 79
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5. Deschamps L, Dokmak S, Guedj N, Ruszniewski P, Sauvanet A, Couvelard A: Mixed endocrine somatostatinoma of the ampulla of vater associated with a neurofibromatosis type 1: a case report and review of the literature. JOP; 2010;11(1):64-8
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  • [Title] Mixed endocrine somatostatinoma of the ampulla of vater associated with a neurofibromatosis type 1: a case report and review of the literature.
  • CONTEXT: Mixed endocrine tumors are double neoplasms with both glandular and endocrine components; these tumors are rare, especially those arising in the ampulla of Vater.
  • We herein describe the first reported case of a mixed endocrine somatostatinoma of the ampulla of Vater associated with neurofibromatosis type 1; we also present a review of the literature of the 7 mixed endocrine tumors of the ampulla which have been reported so far.
  • Endoscopic examination revealed a tumor involving the ampulla of Vater and a CT scan identified stenoses of both the distal common bile duct and the main pancreatic duct.
  • A pancreaticoduodenectomy was performed and pathological examination revealed two tumor components, exocrine (high grade adenoma with infiltrative adenocarcinoma) and endocrine (expressing somatostatin hormone) with lymph node metastases originating from both types.
  • CONCLUSION: Because of their rarity, the diagnosis of ampullary mixed endocrine tumors is difficult.
  • [MeSH-major] Ampulla of Vater. Common Bile Duct Neoplasms / diagnosis. Mixed Tumor, Malignant / diagnosis. Neurofibromatosis 1 / diagnosis. Somatostatinoma / diagnosis


6. Prenzel KL, Warnecke-Eberz U, Brabender J, Baldus SE, Bollschweiler E, Gutschow CA, Drebber U, Hoelscher AH, Schneider PM: Differential c-erbB-1 and c-erbB-2 mRNA expression in cancer of the pancreas compared with cancer of the papilla of Vater. World J Gastroenterol; 2006 Jan 21;12(3):437-42
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  • [Title] Differential c-erbB-1 and c-erbB-2 mRNA expression in cancer of the pancreas compared with cancer of the papilla of Vater.
  • AIM: We examined quantitative mRNA expression of growth factor receptors (c-erbB-1, c-erbB-2) and the anti-apoptosis gene survivin known to be regulated in pancreatic adenocarcinomas and compared the expression pattern with that in carcinomas of the papilla of Vater.
  • METHODS: Quantitative real-time reverse transcriptase-PCR (QRT-PCR, Taqman) was performed to analyze mRNA expression levels of c-erbB-1, c-erbB-2 and survivin in normal and corresponding tumor samples of 31 pancreatic adenocarcinomas and 8 cancers of the papilla of Vater.
  • RESULTS: The overall median mRNA expression of survivin was significantly increased in both adenocarcinoma of the pancreas (P<0.01) and papilla of Vater (P<0.008) compared with uninvolved normal control tissue.
  • In pancreatic cancer, expression of c-erbB-1 was significantly decreased compared with the normal pancreatic tissue (P<0.03), whereas in the cancer of the papilla of Vater expression of c-erbB-2 was significantly downregulated (P<0.05) compared with the paired normal samples.
  • CONCLUSION: The common anti-apoptosis gene survivin is overexpressed both in the cancer of the papilla of Vater and pancreas.
  • In contrast, the growth factor receptor genes c-erbB-1 and c-erbB-2 are differentially regulated in both tumor entities adding further evidence that pancreatic cancer is biologically different from the cancer of papilla of Vater.
  • [MeSH-major] Adenocarcinoma / metabolism. Ampulla of Vater. Common Bile Duct Neoplasms / metabolism. Pancreatic Neoplasms / metabolism. RNA, Messenger / genetics. Receptor, Epidermal Growth Factor / metabolism. Receptor, ErbB-2 / metabolism

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  • (PMID = 16489645.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / BIRC5 protein, human; 0 / Inhibitor of Apoptosis Proteins; 0 / Microtubule-Associated Proteins; 0 / Neoplasm Proteins; 0 / RNA, Messenger; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-2
  • [Other-IDs] NLM/ PMC4066064
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7. Lu B, Cai X, Lu W, Huang Y, Jin X: Laparoscopic pancreaticoduodenectomy to treat cancer of the ampulla of Vater. JSLS; 2006 Jan-Mar;10(1):97-100
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  • [Title] Laparoscopic pancreaticoduodenectomy to treat cancer of the ampulla of Vater.
  • Three patients had duodenal papillary cancer, one had cancer of the head of the pancreas, and one had pancreatic mixed cancer (duodenal papillary cancer, hepatobiliary ductal adenocarcinoma).
  • RESULTS: The pathology diagnosis was well-differentiated duodenum papillary adenocarcinoma in 3 patients, head of pancreas endocrine small cell carcinoma in 1, and duodenum papillary adenoma with malignancy ductal intermediate differentiation adenocarcinoma in 1.

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  • (PMID = 16709370.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3015677
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8. Nagano Y, Sekido H, Matsuoi K, Ohtsuki K, Gorai K, Kunisaki C, Ike H, Imada T, Shimada H: Successful pancreatoduodenectomy for carcinoma of the ampulla of vater after esophagectomy with remnant gastrectomy. Hepatogastroenterology; 2005 May-Jun;52(63):933-5
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  • [Title] Successful pancreatoduodenectomy for carcinoma of the ampulla of vater after esophagectomy with remnant gastrectomy.
  • Duodenoscopy was performed and showed the protruded lesion of the ampulla of Vater, biopsied specimens from this tumor revealed adenocarcinomas.
  • The problem in this case was that the rt middle colic artery (MCA), and the middle colic vein (MCV) tend to be injured because these vessels are situated near the caudal region of the pancreas.
  • Double cancer of the ampulla of Vater and the esophagus are extremely rare, with only 4 cases reported.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Esophageal Neoplasms / surgery. Esophagectomy. Gastrectomy. Gastric Stump / surgery. Neoplasms, Multiple Primary / surgery. Pancreaticoduodenectomy. Postoperative Complications / surgery

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  • (PMID = 15966235.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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9. Falconi M, Crippa S, Domínguez I, Barugola G, Capelli P, Marcucci S, Beghelli S, Scarpa A, Bassi C, Pederzoli P: Prognostic relevance of lymph node ratio and number of resected nodes after curative resection of ampulla of Vater carcinoma. Ann Surg Oncol; 2008 Nov;15(11):3178-86

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  • [Title] Prognostic relevance of lymph node ratio and number of resected nodes after curative resection of ampulla of Vater carcinoma.
  • BACKGROUND: Nodal metastasis is considered a major prognostic factor in patients with ampulla of Vater carcinoma (AVC).
  • [MeSH-major] Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Lymph Nodes / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / secondary. Adenocarcinoma / surgery. Adult. Aged. Aged, 80 and over. Cohort Studies. Duodenal Neoplasms / pathology. Duodenal Neoplasms / secondary. Duodenal Neoplasms / surgery. Female. Follow-Up Studies. Humans. Lymph Node Excision. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / secondary. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy. Prognosis. Prospective Studies. Survival Rate

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  • (PMID = 18712568.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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10. Henson DE, Schwartz AM, Nsouli H, Albores-Saavedra J: Carcinomas of the pancreas, gallbladder, extrahepatic bile ducts, and ampulla of vater share a field for carcinogenesis: a population-based study. Arch Pathol Lab Med; 2009 Jan;133(1):67-71
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  • [Title] Carcinomas of the pancreas, gallbladder, extrahepatic bile ducts, and ampulla of vater share a field for carcinogenesis: a population-based study.
  • CONTEXT: Carcinomas co-occur in the pancreas, extrahepatic bile ducts, and ampulla of Vater.
  • OBJECTIVE: To determine whether a field effect for carcinogenesis exists in the ampulla of Vater, extrahepatic bile ducts, gallbladder, and pancreas.
  • Cases were compared by age frequency density plots, age-specific incidence rates, and logarithmic plots of the age-specific incidence rates and age of diagnosis.
  • Logarithmic plots of the age-specific incidence rates with age of diagnosis produced parallel linear rate patterns for the 4 sites indicative of similar populations for tumor development.
  • CONCLUSIONS: Carcinomas of the pancreas, gallbladder, extrahepatic bile ducts, and ampulla have a common embryonic cellular ancestry, differentiation pathways, mucosal histologic patterns, and population-related tumor development indicating a field effect in carcinogenesis.
  • Pancreatic cancers are most common because the surface area of the pancreas' ductal system is greater than that of the gallbladder, extrahepatic bile ducts, and ampulla.
  • [MeSH-major] Adenocarcinoma / pathology. Bile Duct Neoplasms / pathology. Common Bile Duct Neoplasms / pathology. Gallbladder Neoplasms / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Aged. Ampulla of Vater / pathology. Bile Ducts, Extrahepatic / pathology. Humans. Incidence. Neoplasms, Multiple Primary. Population Surveillance. United States / epidemiology

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  • [CommentIn] Arch Pathol Lab Med. 2009 Jun;133(6):850 [19492873.001]
  • (PMID = 19123739.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Barauskas G, Gulbinas A, Pundzius J: Results of surgical treatment of carcinoma of papilla of Vater. Medicina (Kaunas); 2007;43(6):455-62

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  • [Title] Results of surgical treatment of carcinoma of papilla of Vater.
  • Adenocarcinoma is the most common malignant tumor of the ampulla, but in general, it is still rare.
  • To evaluate immediate postoperative and long-term results, we have collected data prospectively in a specially created database on 21 consecutive patients with adenocarcinoma of the papilla of Vater, operated on at the Department of Surgery, Kaunas University of Medicine Hospital.
  • Pancreas-associated morbidity was 14.3% in the series.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery

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  • (PMID = 17637516.001).
  • [ISSN] 1648-9144
  • [Journal-full-title] Medicina (Kaunas, Lithuania)
  • [ISO-abbreviation] Medicina (Kaunas)
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Lithuania
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12. Ishida M, Egawa S, Sakata N, Mikami Y, Motoi F, Abe T, Fukuyama S, Sunamura M, Furukawa T, Unno M: Intraductal papillary-mucinous adenocarcinoma in the remnant pancreas after pancreatoduodenectomy for cancer of Vater's papilla associated with intraductal papillary-mucinous adenoma. J Hepatobiliary Pancreat Surg; 2007;14(5):522-5
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  • [Title] Intraductal papillary-mucinous adenocarcinoma in the remnant pancreas after pancreatoduodenectomy for cancer of Vater's papilla associated with intraductal papillary-mucinous adenoma.
  • A 72-year-old woman, who had undergone pylorus-preserving pancreatoduodenectomy 3 years before for cancer of Vater's papilla associated with a branch-type intraductal papillary-mucinous adenoma (IPMA), developed dilatation of the main duct and a nodular lesion in the remnant pancreas.
  • Total pancreatectomy was performed, which revealed that the lesion was intraductal papillary-mucinous adenocarcinoma (IPMC) with minimal invasion, suggesting the metachronous multicentric occurrence of this intraductal papillary-mucinous neoplasm (IPMN).
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Ampulla of Vater. Carcinoma, Pancreatic Ductal / diagnosis. Common Bile Duct Neoplasms / surgery. Neoplasms, Multiple Primary / diagnosis. Pancreatic Neoplasms / diagnosis

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  • (PMID = 17909725.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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13. Inagaki M, Obara M, Suzuki S, Ishizaki A, Takahashi K, Matsumoto K, Haneda M, Tokusashi Y, Miyokawa N, Kasai S: Mucinous carcinoma of Vater's ampulla with a unique extension along the main pancreatic duct. J Hepatobiliary Pancreat Surg; 2007;14(5):518-21
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  • [Title] Mucinous carcinoma of Vater's ampulla with a unique extension along the main pancreatic duct.
  • We report a case of mucinous carcinoma of Vater's ampulla with a unique extension along only the main pancreatic duct (MPD) and microinvasion to the pancreas.
  • Abdominal computed tomography (CT) demonstrated swelling in the head of the pancreas with a mass in the duodenum.
  • Hypotonic duodenography and endoscopic examination revealed a well-defined mass, measuring about 25 mm in size, in Vater's ampulla.
  • A biopsy specimen of the tumor showed moderately differentiated adenocarcinoma.
  • A pylorus-preserving pancreaticoduodenectomy with a regional lymphadenectomy was performed, under a preoperative diagnosis of adenocarcinoma of Vater's ampulla with direct invasion into the head of the pancreas.
  • The resected specimen of the duodenum confirmed the presence of the mass, which measured 22 x 15 mm in size, in Vater's ampulla.
  • Microscopically, the tumor consisted of two components: moderately differentiated adenocarcinoma in the peripheral region of the tumor Vater's papilla and mucinous carcinoma in the central region of the tumor.
  • The mucinous carcinoma component uniquely extended along only the MPD with microinvasion to the pancreas.
  • Immunohistochemically, both the moderately differentiated adenocarcinoma and the mucinous carcinoma were positive for cytokeratin 20 (CK20) and negative for cytokeratin 7 (CK7) which is the pattern of intestinal-type carcinoma of Vater's ampulla.
  • We concluded that the original site of this tumor may have been the duodenal epithelium of Vater's ampulla originally moderately differentiated adenocarcinoma-which subsequently changed to mucinous carcinoma that extended along only the MPD with microinvasion to the pancreas.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Ampulla of Vater / pathology. Common Bile Duct Neoplasms / pathology. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 17909724.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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14. Alibegov RA, Prokhorenko TI, Sergeev OA, Khlusov AN: [The long term results and survival prognostic factors of surgical treatment ampulla Vateri cancer]. Khirurgiia (Mosk); 2008;(4):27-30

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  • [Title] [The long term results and survival prognostic factors of surgical treatment ampulla Vateri cancer].
  • Results of radical operative treatment of 21 patients with ampulla Vateri cancer are presented.
  • Factors having prognostic value for survival rate are the stage of disease, metastatic regional spread, tumor invasion in a head of a pancreas, microscopic picture of a pancreatitis in a phase of acute condition.
  • [MeSH-major] Adenocarcinoma / mortality. Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / mortality. Common Bile Duct Neoplasms / surgery. Pancreaticoduodenectomy / methods

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  • (PMID = 18454104.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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15. Ohike N, Kim GE, Tajiri T, Krasinskas A, Basturk O, Coban I, Bandyopadhyay S, Morohoshi T, Goodman M, Kooby DA, Sarmiento JM, Adsay NV: Intra-ampullary papillary-tubular neoplasm (IAPN): characterization of tumoral intraepithelial neoplasia occurring within the ampulla: a clinicopathologic analysis of 82 cases. Am J Surg Pathol; 2010 Dec;34(12):1731-48
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  • [Title] Intra-ampullary papillary-tubular neoplasm (IAPN): characterization of tumoral intraepithelial neoplasia occurring within the ampulla: a clinicopathologic analysis of 82 cases.
  • BACKGROUND: There has been no uniform terminology for systematic analysis of mass-forming preinvasive neoplasms (which we term tumoral intraepithelial neoplasia) that occur specifically within the ampulla.
  • MATERIALS AND METHODS: Three hundred and seventeen glandular neoplasms involving the ampulla were identified through a review of 1469 pancreatoduodenectomies and 11 ampullectomies.
  • Eighty-two neoplasms characterized by substantial preinvasive exophytic component that grew almost exclusively (>75%) within the ampulla (in the ampullary channel or intra-ampullary portions of the very distal segments of the common bile duct or pancreatic duct) were analyzed. RESULTS:.
  • CONCLUSIONS: Tumoral intraepithelial neoplasia occurring within the ampulla are highly analogous to pancreatic or biliary intraductal papillary and tubular neoplasms as evidenced by their papillary and/or tubular growth, variable cell lineage, and spectrum of dysplastic change (adenoma-carcinoma sequence), and thus we propose to refer to these as IAPN.
  • Twenty eight percent (64 of 230) of invasive carcinomas within the ampulla arise in association with IAPNs.

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  • (PMID = 21084962.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P20 CA101936; United States / NCI NIH HHS / CA / P50 CA062924; United States / NCI NIH HHS / CA / P50 CA062924-18; United States / NCI NIH HHS / CA / CA101936
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ NIHMS315774; NLM/ PMC3168573
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16. Voutsadakis IA, Doumas S, Tsapakidis K, Papagianni M, Papandreou CN: Bone and brain metastases from ampullary adenocarcinoma. World J Gastroenterol; 2009 Jun 7;15(21):2665-8
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  • [Title] Bone and brain metastases from ampullary adenocarcinoma.
  • In this report we describe the case of a patient with resected adenocarcinoma of the ampulla of Vater who developed skeletal metastases in the lower extremity and brain metastases.
  • [MeSH-major] Adenocarcinoma / pathology. Ampulla of Vater / pathology. Bone Neoplasms / secondary. Brain Neoplasms / secondary. Common Bile Duct Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Fatal Outcome. Female. Humans. Middle Aged. Neoplasm Metastasis

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  • (PMID = 19496199.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2691500
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17. de Castro SM, van Eijck CH, Rutten JP, Dejong CH, van Goor H, Busch OR, Gouma DJ: Pancreas-preserving total duodenectomy versus standard pancreatoduodenectomy for patients with familial adenomatous polyposis and polyps in the duodenum. Br J Surg; 2008 Nov;95(11):1380-6
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  • [Title] Pancreas-preserving total duodenectomy versus standard pancreatoduodenectomy for patients with familial adenomatous polyposis and polyps in the duodenum.
  • BACKGROUND: Pancreas-preserving total duodenectomy (PPTD) was introduced as a replacement for pancreatoduodenectomy (PD) for familial adenomatous polyposis (FAP).
  • METHODS: All 26 patients who underwent PPTD for FAP in four centres in the Netherlands between January 2000 and January 2007 were compared with a group of 77 patients who had PD for ampulla of Vater adenocarcinoma at one centre during the same interval.
  • RESULTS: Morbidity rates were similar after PPTD for FAP (16 patients, 62 per cent) and PD for ampulla of Vater adenocarcinoma (44 patients, 57 per cent) (P = 0.694).
  • [MeSH-major] Adenocarcinoma / surgery. Adenomatous Polyposis Coli / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Pancreas / surgery. Pancreaticoduodenectomy / methods

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  • [Copyright] Copyright (c) 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
  • (PMID = 18844249.001).
  • [ISSN] 1365-2168
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] England
  • [Number-of-references] 43
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18. Barauskas G, Gulbinas A, Pranys D, Dambrauskas Z, Pundzius J: Tumor-related factors and patient's age influence survival after resection for ampullary adenocarcinoma. J Hepatobiliary Pancreat Surg; 2008;15(4):423-8

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  • [Title] Tumor-related factors and patient's age influence survival after resection for ampullary adenocarcinoma.
  • BACKGROUND/PURPOSE: The majority of surgeons agree that ampullary adenocarcinoma should be removed by partial pancreatoduodenectomy.
  • Favoring extended resection, based on the uncertainty of the preoperative diagnosis and the higher probability of clear resection margins, we aimed to disclose the results of this surgical procedure in terms of postoperative morbidity and mortality, and to identify prognosticators of long-term survival.
  • METHODS: We documented, prospectively, 25 consecutive patients with adenocarcinoma of the papilla of Vater in whom pylorus-preserving pancreatoduodenectomy was performed.
  • RESULTS: Postoperative mortality was 4%, overall morbidity was 32%, and pancreas-associated morbidity was 8%.
  • [MeSH-major] Adenocarcinoma / mortality. Ampulla of Vater. Common Bile Duct Neoplasms / mortality. Pancreaticoduodenectomy

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  • (PMID = 18670845.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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19. O'Connor JK, Sause WT, Hazard LJ, Belnap LP, Noyes RD: Survival after attempted surgical resection and intraoperative radiation therapy for pancreatic and periampullary adenocarcinoma. Int J Radiat Oncol Biol Phys; 2005 Nov 15;63(4):1060-6
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  • [Title] Survival after attempted surgical resection and intraoperative radiation therapy for pancreatic and periampullary adenocarcinoma.
  • PURPOSE: To evaluate a single institution's experience with intraoperative radiation therapy (IORT) in combination with attempted surgical resection for pancreatic and periampullary adenocarcinoma.
  • METHODS AND MATERIALS: From May 1986 until June 2001, 77 patients at LDS Hospital underwent attempted surgical resection and IORT for pancreatic or periampullary adenocarcinoma.
  • Forty-four patients with tumors located in the pancreas and 9 patients with periampullary tumors underwent potentially curative surgical resection and IORT.
  • RESULTS: Patients undergoing a potentially curative resection and IORT for periampullary adenocarcinoma had a median survival of 167 months and a 56% 5-year actuarial survival, compared with a median survival of 16 months and a 19% 5-year actuarial survival for patients undergoing the same treatment for pancreatic adenocarcinoma (p = 0.03).
  • CONCLUSIONS: Intraoperative radiation therapy is well tolerated and does not increase the morbidity or mortality of potentially curative surgical resection for pancreatic or periampullary adenocarcinoma.
  • Patients with periampullary adenocarcinoma have a better prognosis than those with pancreatic adenocarcinoma, and patients with unresectable pancreatic disease fared worse.
  • [MeSH-major] Adenocarcinoma / mortality. Ampulla of Vater. Common Bile Duct Neoplasms / mortality. Pancreatic Neoplasms / mortality

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  • (PMID = 15978737.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] U3P01618RT / Fluorouracil
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20. Riall TS, Cameron JL, Lillemoe KD, Campbell KA, Sauter PK, Coleman J, Abrams RA, Laheru D, Hruban RH, Yeo CJ: Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survival. J Gastrointest Surg; 2005 Dec;9(9):1191-204; discussion 1204-6
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  • [Title] Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survival.
  • The study objective was to update the survival analysis at the 5-year mark of patients undergoing standard versus radical (extended) pancreaticoduodenectomy (PD) for periampullary adenocarcinoma (cancers of the pancreas, ampulla, common bile duct, and duodenum).
  • Five patients were excluded from final analysis because final pathology failed to reveal adenocarcinoma.
  • For pancreatic adenocarcinoma patients, the 1- and 5-year survival rates in the standard group were 75% and 13%, respectively, compared with 73% and 29% in the radical group (P = 0.13).
  • The increased morbidity rate, longer operative time, and similar survival for radical PD led us to conclude that pylorus-preserving PD without retroperitoneal lymphadenectomy should be the procedure of choice for most patients with resectable periampullary adenocarcinoma.
  • While there is an intriguing trend toward improved survival in patients with pancreatic adenocarcinoma in the radical group, this trend may be largely accounted for by the higher incidence of microscopically margin positive resections in the standard resection group (21%) compared with a 5% incidence in the radical group (P = 0.002).
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Gastrectomy / methods. Lymph Node Excision / methods. Pancreaticoduodenectomy / methods

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  • (PMID = 16332474.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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21. Hustinx SR, Hruban RH, Leoni LM, Iacobuzio-Donahue C, Cameron JL, Yeo CJ, Brown PN, Argani P, Ashfaq R, Fukushima N, Goggins M, Kern SE, Maitra A: Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: a potential new target for therapy. Cancer Biol Ther; 2005 Jan;4(1):83-6
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  • [Title] Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: a potential new target for therapy.
  • [MeSH-major] Adenocarcinoma / genetics. Adenocarcinoma / pathology. Common Bile Duct Neoplasms / genetics. Common Bile Duct Neoplasms / pathology. Gene Deletion. Pancreatic Neoplasms / genetics. Pancreatic Neoplasms / pathology. Purine-Nucleoside Phosphorylase / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Ampulla of Vater. Animals. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Oligonucleotide Array Sequence Analysis. Transplantation, Heterologous

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  • [CommentIn] Cancer Biol Ther. 2005 Mar;4(3):347 [15876862.001]
  • (PMID = 15662124.001).
  • [ISSN] 1538-4047
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA62924
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.4.2.1 / Purine-Nucleoside Phosphorylase; EC 2.4.2.28 / 5'-methylthioadenosine phosphorylase
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22. Hassan R, Laszik ZG, Lerner M, Raffeld M, Postier R, Brackett D: Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis. Am J Clin Pathol; 2005 Dec;124(6):838-45
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  • [Title] Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis.
  • We conducted this study to fully characterize mesothelin expression in surgically resected, formalin-fixed, paraffin-embedded tissue specimens of 18 pancreatic adenocarcinomas, 9 adenocarcinomas of the ampulla of Vater, 12 adenocarcinomas of the common bile duct, and 17 cases of chronic pancreatitis.
  • All 18 cases (100%) of pancreatic adenocarcinomas showed mesothelin expression, as did 8 (89%) of 9 cases of ampullar adenocarcinoma and all 12 cases (100%) of common bile duct adenocarcinoma.
  • In all cases of pancreaticobiliary adenocarcinoma, the adjacent normal pancreas did not stain for mesothelin.
  • [MeSH-major] Adenocarcinoma / metabolism. Biomarkers, Tumor / analysis. Membrane Glycoproteins / biosynthesis. Pancreatic Neoplasms / metabolism. Pancreatitis, Chronic / metabolism
  • [MeSH-minor] Common Bile Duct / metabolism. Common Bile Duct / pathology. GPI-Linked Proteins. Humans. Immunohistochemistry. Pancreas / metabolism

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  • (PMID = 16416732.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / mesothelin
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23. de Castro SM, Singhal D, Aronson DC, Busch OR, van Gulik TM, Obertop H, Gouma DJ: Management of solid-pseudopapillary neoplasms of the pancreas: a comparison with standard pancreatic neoplasms. World J Surg; 2007 May;31(5):1130-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of solid-pseudopapillary neoplasms of the pancreas: a comparison with standard pancreatic neoplasms.
  • BACKGROUND: Solid-pseudopapillary neoplasms (SPNs) of the pancreas are increasingly diagnosed, but the exact surgical management in terms of extent of the resection is not well defined.
  • The 5-year survival of SPN patients was 100% and is significantly better compared with survival of patients with pancreatic adenocarcinoma (12%, p < 0.001) and ampulla of Vater adenocarcinoma (22%, p = 0.005).
  • CONCLUSIONS: Patients with solid-pseudopapillary neoplasms of the pancreas present differently and the course of the disease is more benign.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / surgery

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  • (PMID = 17429567.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2813543
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24. Rautou PE, Hammel P, Couvelard A, Rivet P, Aubert A, Lévy P, Ruszniewski P: [Suspected malignant cancer of the pancreas associated with pseudo-invasive duodenal hamartomas in a patient with Peutz-Jeghers syndrome]. Gastroenterol Clin Biol; 2007 May;31(5):547-51
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  • [Title] [Suspected malignant cancer of the pancreas associated with pseudo-invasive duodenal hamartomas in a patient with Peutz-Jeghers syndrome].
  • Because duodenal and/or pancreatic cancer was suspected due to weight loss, the pancreatic and bile duct obstruction, and the increased risk of small intestine and pancreatic adenocarcinoma in patients with PSJ, a pancreatoduodenectomy was performed.
  • Pathological examination revealed a duodenal polyp with epithelial misplacement invading the ampulla and compressing the main bile duct.
  • [MeSH-minor] Adult. Ampulla of Vater / pathology. Cholestasis, Extrahepatic / etiology. Common Bile Duct Diseases / complications. Humans. Male. Pancreatitis, Chronic / etiology

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  • (PMID = 17541348.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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25. Parthasarathy S, Pottakkat B, Yootla M, Reddy SN, Reddy KM: Synchronous adenocarcinomas of the papilla major and minor. JOP; 2008;9(3):332-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There was a growth in the ampulla of Vater and another in the region of the minor duodenal papilla.
  • [MeSH-major] Adenocarcinoma / diagnosis. Ampulla of Vater. Carcinoma, Pancreatic Ductal / complications. Carcinoma, Pancreatic Ductal / diagnosis. Common Bile Duct Neoplasms / complications. Common Bile Duct Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Pancreatic Ducts
  • [MeSH-minor] Female. Humans. Jaundice / diagnosis. Jaundice / etiology. Middle Aged

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  • (PMID = 18469449.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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26. Ogawa H, Itoh S, Ikeda M, Suzuki K, Naganawa S: Intraductal papillary mucinous neoplasm of the pancreas: assessment of the likelihood of invasiveness with multisection CT. Radiology; 2008 Sep;248(3):876-86
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraductal papillary mucinous neoplasm of the pancreas: assessment of the likelihood of invasiveness with multisection CT.
  • RESULTS: The following findings showed significant differences among the three groups: maximum diameter of the main pancreatic duct (MPD), size (length of major axis) of the largest mural nodule in the MPD or in any associated cystic lesion, abnormal attenuating area in the surrounding parenchyma, calcification in the lesion, protrusion of the MPD into the ampulla of Vater, and bile duct dilatation.
  • [MeSH-major] Adenocarcinoma, Mucinous / radiography. Adenoma / radiography. Pancreatic Neoplasms / radiography. Papilloma, Intraductal / radiography. Radiographic Image Enhancement / methods. Tomography, X-Ray Computed / methods

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  • [Copyright] RSNA, 2008
  • (PMID = 18632526.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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27. Bahra M, Langrehr JM, Neuhaus P: [Carcinomas of the distal bile duct]. Chirurg; 2006 Apr;77(4):335-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cancer of the distal bile duct has to be distinguished from ductal adenocarcinoma of the pancreas and carcinoma of the ampulla of Vater.
  • [MeSH-minor] Ampulla of Vater / pathology. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / diagnosis. Common Bile Duct Neoplasms / mortality. Common Bile Duct Neoplasms / pathology. Common Bile Duct Neoplasms / surgery. Humans. Lymph Node Excision / methods. Neoplasm Invasiveness. Neoplasm Staging. Pancreaticoduodenectomy / methods. Prognosis. Survival Rate

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  • (PMID = 16523255.001).
  • [ISSN] 0009-4722
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  • [ISO-abbreviation] Chirurg
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28. Morris-Stiff G, Alabraba E, Tan YM, Shapey I, Bhati C, Tanniere P, Mayer D, Buckels J, Bramhall S, Mirza DF: Assessment of survival advantage in ampullary carcinoma in relation to tumour biology and morphology. Eur J Surg Oncol; 2009 Jul;35(7):746-50
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  • INTRODUCTION: Carcinoma of the ampulla of Vater is said to carry a significantly better prognosis than pancreatic ductal adenocarcinomas arising in the pancreatic head.
  • Patients with a pathologically confirmed ampullary (AMP) tumour were compared to those with a carcinoma of the head of the pancreas (HOP).
  • [MeSH-major] Adenocarcinoma / pathology. Ampulla of Vater. Common Bile Duct Neoplasms / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 19167859.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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29. Shao YF, Wu TC, Shan Y, Wu JX, Wang X, Zhao P: [Clinico-pathological characteristics of surgical effect on periampullary cancers: report of 631 cases]. Zhonghua Yi Xue Za Zhi; 2005 Mar 2;85(8):510-3
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  • RESULTS: The characteristics of different periampullary cancers, in the order of carcinoma of head of pancreas (n = 352), carcinoma of common bile duct (n = 42), carcinoma of Vater's ampulla (n = 189), and duodenal cancer (n = 48) were as follows:.
  • (4) adenocarcinoma accounted for 88%.
  • [MeSH-major] Ampulla of Vater. Common Bile Duct Neoplasms / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adult. Aged. Aged, 80 and over. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Pancreatectomy. Retrospective Studies

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  • (PMID = 15949327.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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30. Akatsu T, Aiura K, Takahashi S, Kameyama K, Kitajima M, Kitagawa Y: Recurrent pancreatitis caused by ampullary carcinoma and minor papilla adenoma in familial polyposis: report of a case. Surg Today; 2008;38(5):440-4
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  • He had experienced several episodes of upper abdominal pain and ultrasonography and computed tomography (CT) showed diffuse calcification of the atrophic pancreas, suggestive of chronic pancreatitis.
  • Upper endoscopy showed multiple duodenal adenomas including carcinoma involving the papilla of Vater.
  • [MeSH-major] Adenocarcinoma / etiology. Adenoma / etiology. Adenomatous Polyposis Coli / complications. Ampulla of Vater. Common Bile Duct Neoplasms / etiology. Pancreatic Neoplasms / etiology. Pancreatitis / etiology

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  • (PMID = 18560968.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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31. Warnecke-Eberz U, Prenzel KL, Baldus SE, Metzger R, Dienes HP, Bollschweiler E, Hoelscher AH, Schneider PM: Significant down-regulation of the plasminogen activator inhibitor 1 mRNA in pancreatic cancer. Pancreas; 2008 Mar;36(2):173-7
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  • OBJECTIVES: We examined mRNA expression of the urokinase-type plasminogen activator (uPA), its receptor (uPAR), and the plasminogen activator inhibitor 1 (PAI-1) in a panel of adenocarcinomas of the pancreas (PC) and cancers of the papilla of Vater (CPV).
  • [MeSH-major] Adenocarcinoma / genetics. Ampulla of Vater / pathology. Common Bile Duct Neoplasms / genetics. Gene Expression Regulation, Neoplastic. Pancreatic Neoplasms / genetics. Plasminogen Activator Inhibitor 1 / genetics. RNA, Messenger / analysis

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  • (PMID = 18376309.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / PLAUR protein, human; 0 / Plasminogen Activator Inhibitor 1; 0 / RNA, Messenger; 0 / Receptors, Cell Surface; 0 / Receptors, Urokinase Plasminogen Activator; 0 / SERPINE1 protein, human; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator
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32. Relles D, Baek J, Witkiewicz A, Yeo CJ: Periampullary and duodenal neoplasms in neurofibromatosis type 1: two cases and an updated 20-year review of the literature yielding 76 cases. J Gastrointest Surg; 2010 Jun;14(6):1052-61
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  • Tumor location was the duodenum (60%), ampulla (31%), pancreas (5%), or bile duct/gallbladder (4%).
  • Tumor type was reported as somatostatinoma (40%), GIST (34%), adenocarcinoma (8%), carcinoid (6%), neurofibroma (5%), schwannoma (4%), or gangliocytic paraganglioma (3%).
  • [MeSH-major] Ampulla of Vater. Common Bile Duct Neoplasms / diagnosis. Duodenal Neoplasms / diagnosis. Neurofibromatosis 1 / complications

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  • (PMID = 20300877.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 76
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33. Alibegov RA, Prokhorenko TI, Sergeev OA, Khlusov AN: [Clinico-morphological factors of prognosis in cancer of the major duodenum papilla]. Vestn Khir Im I I Grek; 2008;167(2):26-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The data of a univariant analysis show that favorable factors of survival are the early stage of the tumor disease, the absence of metastatic lesion of the regional lymph nodes, tumor invasion into the pancreas and a microscopic picture of pancreatitis in the stage of exacerbation.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Pancreaticoduodenectomy / methods

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  • (PMID = 18522181.001).
  • [ISSN] 0042-4625
  • [Journal-full-title] Vestnik khirurgii imeni I. I. Grekova
  • [ISO-abbreviation] Vestn. Khir. Im. I. I. Grek.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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34. Heinrich S, Clavien PA: Ampullary cancer. Curr Opin Gastroenterol; 2010 May;26(3):280-5
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  • As cancer with intestinal differentiation shares a similar biology with colon cancer, and the pancreatobiliary differentiation is close to ductal adenocarcinoma of the pancreas, adjuvant chemotherapy should probably be given according to colon cancer (intestinal) and pancreatic cancer (pancreatobiliary), respectively.
  • SUMMARY: The recent research suggests that the histological differentiation of periampullary cancer is more important than the anatomical location (ampulla).
  • [MeSH-major] Ampulla of Vater. Common Bile Duct Neoplasms / pathology

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  • (PMID = 20168227.001).
  • [ISSN] 1531-7056
  • [Journal-full-title] Current opinion in gastroenterology
  • [ISO-abbreviation] Curr. Opin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 43
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35. Barinagarrementeria R: [Update on endoscopic management of malignant obstructive jaundice]. Rev Gastroenterol Mex; 2005 Jul;70 Suppl 1:95-106
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  • The diagnosis of bilio-pancreatic diseases is carried out when patients present symptoms of biliary obstruction.
  • The majority of these patients cannot receive curative treatment at the time of the diagnosis.
  • [MeSH-major] Adenocarcinoma / complications. Ampulla of Vater. Bile Duct Neoplasms / complications. Bile Ducts, Intrahepatic. Cholangiocarcinoma / complications. Cholangiopancreatography, Endoscopic Retrograde. Cholangiopancreatography, Magnetic Resonance. Common Bile Duct Neoplasms / complications. Jaundice, Obstructive / etiology. Pancreatic Neoplasms / complications
  • [MeSH-minor] Cholangiography. Cholestasis, Extrahepatic / diagnosis. Cholestasis, Intrahepatic / diagnosis. Common Bile Duct / pathology. Diagnosis, Differential. Endosonography. Humans. Neoplasm Staging. Palliative Care. Pancreas / pathology. Tomography, Spiral Computed

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  • (PMID = 17469413.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] Mexico
  • [Number-of-references] 101
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36. Giannopoulos G, Kavantzas N, Parasi A, Tiniakos D, Peros G, Tzanakis N, Patsouris E, Pavlakis K: Morphometric microvascular characteristics in the prognosis of pancreatic and ampullary carcinoma. Pancreas; 2007 Jul;35(1):47-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / blood supply. Adenocarcinoma / pathology. Carcinoma, Pancreatic Ductal / blood supply. Carcinoma, Pancreatic Ductal / pathology. Pancreatic Neoplasms / blood supply. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Ampulla of Vater / blood supply. Ampulla of Vater / metabolism. Ampulla of Vater / pathology. Antigens, CD34 / metabolism. Female. Humans. Kaplan-Meier Estimate. Lymph Nodes / metabolism. Lymph Nodes / pathology. Male. Microcirculation / pathology. Multivariate Analysis. Neoplasm Staging. Neovascularization, Pathologic / pathology. Pancreas / blood supply. Pancreas / metabolism. Pancreas / pathology. Pancreatic Ducts / blood supply. Pancreatic Ducts / metabolism. Pancreatic Ducts / pathology. Prognosis

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  • (PMID = 17575545.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34
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37. Westgaard A, Tafjord S, Farstad IN, Cvancarova M, Eide TJ, Mathisen O, Clausen OP, Gladhaug IP: Resectable adenocarcinomas in the pancreatic head: the retroperitoneal resection margin is an independent prognostic factor. BMC Cancer; 2008;8:5
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  • BACKGROUND: The retroperitoneal margin is frequently microscopically tumour positive in non-curative periampullary adenocarcinoma resections.
  • The periampullary cancer origin (pancreas, ampulla, distal bile duct or duodenum) was registered prospectively and reevaluated retrospectively.
  • Associations between histopathologic factors and survival were also evaluated by unadjusted and adjusted Cox regression analysis, including stepwise variable selection, in order to identify factors that independently predict a poor prognosis after periampullary adenocarcinoma resections.
  • CONCLUSION: Serial perpendicular sectioning of the retroperitoneal resection margin demonstrates that tumour involvement of this margin independently predicts survival after pancreaticoduodenectomy for adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatic Neoplasms / surgery. Retroperitoneal Neoplasms / surgery. Retroperitoneal Space / pathology. Retroperitoneal Space / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Ampulla of Vater / pathology. Disease-Free Survival. Female. Humans. Male. Middle Aged. Pancreaticoduodenectomy. Prognosis. Retrospective Studies

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  • [Cites] Surgery. 2006 Nov;140(5):764-72 [17084719.001]
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  • (PMID = 18194510.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2249586
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38. Jover JM, Carabias A, Fuerte S, Ríos R, Ortega I, Limones M: [Results of defunctionalized jejunal loop after pancreaticoduodenectomy]. Cir Esp; 2006 Dec;80(6):373-7
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  • OBJECTIVE: We evaluated the use of a defunctionalized jejunal loop for the pancreas after pancreaticoduodenectomy.
  • MATERIAL AND METHODS: Between 1991 and 2005, the findings in 80 patients were analyzed in this prospective study of the use of a defunctionalized jejunal loop for the pancreas as a reconstructive procedure following pancreaticoduodenectomy.
  • The following clinical variables were recorded: age, sex, diameter of the main pancreatic duct, pancreas texture, operating time, intraoperative blood transfusion, mean length of hospital stay, and operative mortality.
  • CONCLUSION: After pancreaticoduodenectomy, reconstruction with a defunctionalized jejunal loop for the pancreas is a safe and effective technique.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Cystadenocarcinoma / surgery. Cystadenoma / surgery. Jejunum / surgery. Pancreatic Fistula. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy. Pancreaticojejunostomy. Postoperative Complications

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  • (PMID = 17192221.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Spain
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39. Singh A, Singh T, Chaudhary A: Synchronous resection of solitary liver metastases with pancreaticoduodenectomy. JOP; 2010;11(5):434-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / surgery. Liver Neoplasms / surgery. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Ampulla of Vater / pathology. Ampulla of Vater / surgery. Female. Hepatectomy / methods. Humans. Intraoperative Period. Male. Middle Aged. Retrospective Studies. Time Factors. Young Adult

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  • [CommentIn] JOP. 2011 Jan;12(1):68-9; author reply 71 [21206108.001]
  • (PMID = 20818110.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Italy
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40. Niu GM, Jin DY, Ji Y, Hou J, Wang DS, Lou WH: Survival analysis of pancreatic and periampullary collision cancers. J Dig Dis; 2010 Aug;11(4):231-6
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  • Collision cancers are very rare in the pancreas and periampullary region.
  • The aim of this study was to analyze the clinical and pathological features and prognosis of collision cancer in the pancreas and periampullary region.
  • METHODS: Patients with collision cancers of the pancreas and periampullary region (n= 10) who had undergone radical surgery were retrospectively studied.
  • CONCLUSION: Collision cancers of the pancreas and periampullary region are difficult to diagnose preoperatively.
  • [MeSH-major] Adenocarcinoma / pathology. Ampulla of Vater / pathology. Common Bile Duct Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 20649736.001).
  • [ISSN] 1751-2980
  • [Journal-full-title] Journal of digestive diseases
  • [ISO-abbreviation] J Dig Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
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41. Defrain C, Chang CY, Srikureja W, Nguyen PT, Gu M: Cytologic features and diagnostic pitfalls of primary ampullary tumors by endoscopic ultrasound-guided fine-needle aspiration biopsy. Cancer; 2005 Oct 25;105(5):289-97

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-guided FNAB) is highly sensitive and specific in cytologic diagnosis and clinical staging of malignant neoplasms of the gastrointestinal tract, pancreas, liver, and lymph nodes.
  • The number of passes necessary to arrive at a preliminary diagnosis during adequacy assessment was documented.
  • Adenocarcinoma was diagnosed in 13 patients.
  • Atypical cells were found in six patients, four of which were suspicious for adenocarcinoma and two of which were consistent with reactive atypia.
  • Thirteen patients had a diagnosis that was negative for malignant cells.
  • The consistent cytologic features in specimens that were positive or suspicious for adenocarcinoma included high cellularity, single cells, 3-dimensional cell balls, high nuclear-to-cytoplasmic ratio, prominent nucleoli, coarse/uneven distribution of chromatin, and necrosis.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Adenoma / diagnosis. Adenoma / pathology. Ampulla of Vater / pathology. Common Bile Duct Neoplasms / diagnosis. Common Bile Duct Neoplasms / pathology

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  • (PMID = 15986397.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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42. Sudo T, Murakami Y, Uemura K, Hayashidani Y, Hashimoto Y, Ohge H, Shimamoto F, Sueda T: Prognostic impact of perineural invasion following pancreatoduodenectomy with lymphadenectomy for ampullary carcinoma. Dig Dis Sci; 2008 Aug;53(8):2281-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Lymph Node Excision. Pancreaticoduodenectomy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Duodenum / pathology. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Pancreas / pathology. Retrospective Studies. Treatment Outcome

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  • (PMID = 18095164.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Hustinx SR, Fukushima N, Zahurak ML, Riall TS, Maitra A, Brosens L, Cameron JL, Yeo CJ, Offerhaus GJ, Hruban RH, Goggins M: Expression and prognostic significance of 14-3-3sigma and ERM family protein expression in periampullary neoplasms. Cancer Biol Ther; 2005 May;4(5):596-601
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  • Two-hundred fourty-four (82%) primary infiltrating adenocarcinomas of the pancreas demonstrated positive expression of the 14-3-3sigma, 45 (15%) showed weak immunolabelling, and 9 (3%) were negative.
  • Aberrant expression of 14-3-3sigma may contribute to the outcome of patients with pancreatic ductal adenocarcinoma.
  • [MeSH-major] Ampulla of Vater / metabolism. Biomarkers, Tumor / metabolism. Common Bile Duct Diseases / metabolism. DNA-Binding Proteins / metabolism. Exonucleases / metabolism. Neoplasm Proteins / metabolism. Pancreatic Neoplasms / diagnosis. Pancreatic Neoplasms / metabolism. Transcription Factors / metabolism
  • [MeSH-minor] 14-3-3 Proteins. Adenocarcinoma / metabolism. Adenocarcinoma, Mucinous / metabolism. Adult. Aged. Aged, 80 and over. Carcinoma, Pancreatic Ductal / metabolism. Exoribonucleases. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Male. Middle Aged. Multivariate Analysis. Prognosis. Retrospective Studies

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  • (PMID = 15908786.001).
  • [ISSN] 1538-4047
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 14-3-3 Proteins; 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / ETV5 protein, human; 0 / Neoplasm Proteins; 0 / Transcription Factors; EC 3.1.- / Exonucleases; EC 3.1.- / Exoribonucleases; EC 3.1.- / SFN protein, human
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44. Kim YK, Han YM, Kim CS: Usefulness of fat-suppressed T1-weighted MRI using orally administered superparamagnetic iron oxide for revealing ampullary carcinomas. J Comput Assist Tomogr; 2007 Jul-Aug;31(4):519-25
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  • The images were compared quantitatively by measuring the tumor-pancreas (duodenum) contrast-to-noise ratio and, qualitatively, by evaluating tumor conspicuity.
  • RESULTS: For the tumor-pancreas (duodenum) contrast-to-noise ratio, the FLASH was significantly higher than those of the dynamic set and RT-TSE (P < 0.05).
  • [MeSH-major] Adenocarcinoma / diagnosis. Ampulla of Vater. Common Bile Duct Neoplasms / diagnosis. Contrast Media. Ferric Compounds. Image Enhancement / methods. Magnetic Resonance Imaging / methods

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  • (PMID = 17882025.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Ferric Compounds; 1K09F3G675 / ferric oxide
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45. Valls C: [Obstructive Jaundice: diagnostic and therapeutic management]. J Radiol; 2006 Apr;87(4 Pt 2):460-78
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  • The purpose of this article is to provide an update on imaging techniques for diagnosis and staging of clinical conditions leading to obstructive jaundice.
  • Imaging and treatment strategies will be discussed in order to provide an optimal diagnosis and staging with the least invasive techniques in order to minimize complications in these patients.
  • [MeSH-major] Bile Duct Neoplasms / diagnosis. Jaundice, Obstructive / diagnosis. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / radiography. Adenocarcinoma / surgery. Aged. Ampulla of Vater. Bile Ducts, Intrahepatic. Cholangiocarcinoma / diagnosis. Cholangiocarcinoma / radiography. Cholangiopancreatography, Magnetic Resonance. Common Bile Duct Neoplasms / diagnosis. Common Bile Duct Neoplasms / radiography. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Metastasis. Pancreas / abnormalities. Pancreatic Pseudocyst / diagnosis. Pancreatic Pseudocyst / radiography. Pancreatitis, Chronic / diagnosis. Pancreatitis, Chronic / radiography. Risk Factors. Tomography, X-Ray Computed

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  • (PMID = 16691176.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 44
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46. Bloomston M, Ellison EC, Muscarella P, Al-Saif O, Martin EW, Melvin WS, Frankel WL: Stromal osteonectin overexpression is associated with poor outcome in patients with ampullary cancer. Ann Surg Oncol; 2007 Jan;14(1):211-7
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  • Immunohistochemical staining for osteonectin was undertaken and compared with staining in chronic pancreatitis (n = 13) and normal pancreas (n = 19).
  • RESULTS: Osteonectin was significantly (P < .05, Fisher's exact test) overexpressed in the stroma of ampullary cancers (90%) relative to chronic pancreatitis (62%) and normal pancreas (0%).
  • [MeSH-major] Adenocarcinoma / chemistry. Ampulla of Vater. Biomarkers, Tumor / analysis. Common Bile Duct Neoplasms / chemistry. Osteonectin / analysis

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  • (PMID = 17080236.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MUC2 protein, human; 0 / Mucin-1; 0 / Mucin-2; 0 / Mucins; 0 / Osteonectin; 106441-73-0 / Osteopontin
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47. Gaedcke J, Gunawan B, Grade M, Szöke R, Liersch T, Becker H, Ghadimi BM: The mesopancreas is the primary site for R1 resection in pancreatic head cancer: relevance for clinical trials. Langenbecks Arch Surg; 2010 Apr;395(4):451-8
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  • RESULTS: Thirty-five patients were excluded from the analysis owing to the pathohistological diagnosis; only pancreatic ductal adenocarcinoma, distal bile duct adenocarcinoma, and periampullary adenocarcinoma were included.

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  • (PMID = 19418067.001).
  • [ISSN] 1435-2451
  • [Journal-full-title] Langenbeck's archives of surgery
  • [ISO-abbreviation] Langenbecks Arch Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2848727
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48. Kepron C, Kapila V, Hanna S, Khalifa MA: Periampullary carcinoid of the ampulla of Vater presenting as an intraductal papillary mucinous tumour of the pancreas: a sheep in wolf's clothing. Can J Surg; 2008 Jun;51(3):E67-8

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  • [Title] Periampullary carcinoid of the ampulla of Vater presenting as an intraductal papillary mucinous tumour of the pancreas: a sheep in wolf's clothing.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Ampulla of Vater. Carcinoma, Pancreatic Ductal / diagnosis. Common Bile Duct Neoplasms / diagnosis

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  • (PMID = 18682788.001).
  • [ISSN] 1488-2310
  • [Journal-full-title] Canadian journal of surgery. Journal canadien de chirurgie
  • [ISO-abbreviation] Can J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2496582
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49. Labat-Debelleix V, d'Alteroche L, Abidine Benchellal Z, Duboeuf T, Guyétant S, Henry Metman E: [Pancreatic adenocarcinoma complicating a cystic dystrophy on an ectopic pancreas in the ampullar region]. Gastroenterol Clin Biol; 2008 Jun-Jul;32(6-7):653-5
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  • [Title] [Pancreatic adenocarcinoma complicating a cystic dystrophy on an ectopic pancreas in the ampullar region].
  • [MeSH-major] Adenocarcinoma / complications. Adenocarcinoma / pathology. Ampulla of Vater. Choristoma / complications. Common Bile Duct Diseases / complications. Pancreas. Pancreatic Neoplasms / complications. Pancreatic Neoplasms / pathology

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  • (PMID = 18486383.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] France
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50. Lee EJ, Joo KR, Cha JM, Shin HP, Jung SW, Lee JI, Kim GY: Intra-ampullary protruding mass: unusual presentation of mucinous carcinoma of the pancreas. Endoscopy; 2009;41 Suppl 2:E74-5
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intra-ampullary protruding mass: unusual presentation of mucinous carcinoma of the pancreas.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Ampulla of Vater / pathology. Common Bile Duct Neoplasms / secondary. Pancreatic Neoplasms / pathology

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  • (PMID = 19370519.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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51. Alsaif F, Molinari M, Al-Masloom A, Lakey JR, Kin T, Shapiro AM: Pancreatic islet autotransplantation with completion pancreatectomy in the management of uncontrolled pancreatic fistula after whipple resection for ampullary adenocarcinoma. Pancreas; 2006 May;32(4):430-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pancreatic islet autotransplantation with completion pancreatectomy in the management of uncontrolled pancreatic fistula after whipple resection for ampullary adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Islets of Langerhans Transplantation. Pancreatectomy. Pancreatic Fistula / surgery

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  • (PMID = 16670628.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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52. Manolakis AC, Kardasi M, Tsiopoulos FD, Kapsoritakis AN, Psychos AK, Potamianos SP: Progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) with fatal outcome, after the manifestation of an ampullary adenocarcinoma. Pancreas; 2010 Jul;39(5):688-9
Hazardous Substances Data Bank. AMANTADINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) with fatal outcome, after the manifestation of an ampullary adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Ampulla of Vater. Common Bile Duct Neoplasms / diagnosis. Supranuclear Palsy, Progressive / etiology

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  • (PMID = 20562584.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antiparkinson Agents; 0 / Indoles; 030PYR8953 / ropinirole; 46627O600J / Levodopa; BF4C9Z1J53 / Amantadine
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