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Items 1 to 89 of about 89
1. Colvin M, Delis A, Bracamonte E, Villar H, Leon LR Jr: Infiltrating adenocarcinoma arising in a villous adenoma of the anal canal. World J Gastroenterol; 2009 Jul 28;15(28):3560-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infiltrating adenocarcinoma arising in a villous adenoma of the anal canal.
  • In particular, adenomas and adenocarcinomas are distinctly rare entities in this region.
  • We describe an infiltrating, well-differentiated adenocarcinoma arising in a villous adenoma from the distal anal canal, in an otherwise healthy patient at low risk for gastrointestinal malignancy.
  • Microscopic evaluation revealed an infiltrating well-differentiated adenocarcinoma, arising from a villous adenoma.
  • Our report is the first describing the possible malignant degeneration of a villous adenoma in the anal canal.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Anal Canal / pathology

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  • [Cites] Am Surg. 2000 Aug;66(8):789-92 [10966042.001]
  • [Cites] Colorectal Dis. 2008 Jul;10(6):621-3 [17949443.001]
  • [Cites] Histopathology. 2002 Mar;40(3):302-4 [11895502.001]
  • [Cites] Dis Colon Rectum. 2003 Oct;46(10):1320-4 [14530668.001]
  • [Cites] Surg Oncol Clin N Am. 2004 Apr;13(2):249-62 [15137955.001]
  • [Cites] Cancer. 1975 Dec;36(6):2251-70 [1203876.001]
  • [Cites] N Engl J Med. 1988 Sep 1;319(9):525-32 [2841597.001]
  • [Cites] N Engl J Med. 1993 Dec 30;329(27):1977-81 [8247072.001]
  • [Cites] Br J Surg. 1994 Apr;81(4):500-8 [8205420.001]
  • [Cites] Br J Surg. 1995 Dec;82(12):1634 [8548224.001]
  • [Cites] J Clin Pathol. 2005 Feb;58(2):217-9 [15677547.001]
  • [Cites] World J Gastroenterol. 2006 Mar 21;12(11):1780-1 [16586552.001]
  • [Cites] Colorectal Dis. 2006 May;8(4):296-301 [16630233.001]
  • [Cites] Eur J Dermatol. 2006 Sep-Oct;16(5):576-8 [17101482.001]
  • [Cites] World J Gastroenterol. 2006 Dec 7;12(45):7304-8 [17143945.001]
  • [Cites] Gan To Kagaku Ryoho. 2006 Nov;33(12):1977-9 [17212165.001]
  • [Cites] Oncologist. 2007 May;12(5):524-34 [17522240.001]
  • [Cites] Surg Today. 2007;37(7):596-9 [17593481.001]
  • [Cites] Tech Coloproctol. 2007 Dec;11(4):340-2 [18060528.001]
  • [Cites] J Am Osteopath Assoc. 2001 Aug;101(8):450-3 [11526879.001]
  • (PMID = 19630115.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2715986
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2. Joniau S, Lerut E, Van Poppel H: A Giant Mucinous Adenocarcinoma Arising within a Villous Adenoma of the Urachus: Case Report and Review of the Literature. Case Rep Med; 2009;2009:818646
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A Giant Mucinous Adenocarcinoma Arising within a Villous Adenoma of the Urachus: Case Report and Review of the Literature.
  • We present an exceptional case of a giant urachal tumor, consisting of both villous adenoma and mucinous adenocarcinoma of the urachus.
  • Initial transurethral biopsies showed only a villous adenoma of the urachus.
  • The indication for surgery was based on the typical imaging aspects, raising the suspicion of an underlying urachal adenocarcinoma (size and location).
  • Indeed, at final histopathology a concomitant well-differentiated adenocarcinoma of the urachus confined to the urachal mucosa was found.
  • Only three previous cases of urachal adenocarcinoma associated with villous adenoma have been described.

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  • [Cites] J Urol. 1978 Feb;119(2):287-8 [633500.001]
  • [Cites] J Urol. 1986 Jun;135(6):1240-4 [3712579.001]
  • [Cites] J Urol. 1984 Jan;131(1):1-8 [6361280.001]
  • [Cites] J Clin Pathol. 2003 Jun;56(6):465-7 [12783975.001]
  • [Cites] J Urol. 1994 Feb;151(2):365-6 [8283526.001]
  • [Cites] J Clin Pathol. 1993 May;46(5):450-2 [8320324.001]
  • [Cites] Changgeng Yi Xue Za Zhi. 1995 Sep;18(3):266-9 [8521338.001]
  • [Cites] Am J Clin Pathol. 1983 Jun;79(6):728-31 [6846264.001]
  • (PMID = 20182635.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2825668
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3. Shivaprakash HN, Jayashree K, Girish M: Villous adenoma: a rare tumor of vaginal vault. Indian J Pathol Microbiol; 2008 Apr-Jun;51(2):265-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Villous adenoma: a rare tumor of vaginal vault.
  • Villous adenomas are extremely rare tumors in the vagina and are indistinguishable from their colonic counterparts.
  • The significance of this lesion lies in the fact that it has to be distinguished from metastatic adenocarcinoma from other sites.
  • We present a case of villous adenoma of vaginal vault, a rare site of presentation in a 30-year-old female.
  • [MeSH-major] Adenoma, Villous / pathology. Vaginal Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / secondary. Adult. Diagnosis, Differential. Female. Humans

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  • (PMID = 18603704.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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4. Sun JH, Chao M, Zhang SZ, Zhang GQ, Li B, Wu JJ: Coexistence of small cell neuroendocrine carcinoma and villous adenoma in the ampulla of Vater. World J Gastroenterol; 2008 Aug 7;14(29):4709-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coexistence of small cell neuroendocrine carcinoma and villous adenoma in the ampulla of Vater.
  • Small cell neuroendocrine carcinoma of the ampulla of Vater is extremely rare and different from the common ampullary adenocarcinoma.
  • The ampullary adenoma is also a rare neoplasm and has the potential to develop an adenocarcinoma.
  • We herein describe an unusual case of a small cell neuroendocrine carcinoma associated with a villous adenoma in the ampulla of Vater with emphasis on computed tomography (CT) and histopathological findings.
  • [MeSH-major] Adenoma, Villous / complications. Ampulla of Vater. Carcinoma, Neuroendocrine / complications. Common Bile Duct Neoplasms / complications

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  • [Cites] Hepatogastroenterology. 2001 Nov-Dec;48(42):1588-93 [11813580.001]
  • [Cites] Gastrointest Endosc. 2002 Jun;55(7):870-6 [12024143.001]
  • [Cites] Arch Pathol Lab Med. 2003 Feb;127(2):221-3 [12562240.001]
  • [Cites] J Clin Oncol. 2004 Jul 1;22(13):2730-9 [15226341.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 2004;11(4):232-8 [15368106.001]
  • [Cites] J Natl Cancer Inst. 1981 Sep;67(3):607-12 [6268879.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 2006;13(5):450-3 [17013721.001]
  • [Cites] Am J Surg Pathol. 1990 Aug;14(8):703-13 [1696069.001]
  • [Cites] Gut. 1991 Dec;32(12):1558-61 [1773967.001]
  • [Cites] Cancer. 1992 Sep 15;70(6):1502-4 [1325273.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 2004;11(1):56-60 [15747032.001]
  • [Cites] Am J Surg Pathol. 2005 May;29(5):588-94 [15832081.001]
  • [Cites] Clin Gastroenterol. 1986 Apr;15(2):439-56 [3731520.001]
  • (PMID = 18698690.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2738800
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5. Guan J, Chen J, Luo YF, Cao JL, Zhao H, Hao J: [Expression of survivin in colorectal adenoma and adenocarcinoma]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2007 Jun;29(3):398-401
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of survivin in colorectal adenoma and adenocarcinoma].
  • METHODS Immunohistochemistry staining was performed by two-step EnVision technique for the paraffin sections, which included 90 adenomas, 25 ademomas with high-grade glandular intraepithelial neoplasia, and 108 colorectal adenocarcinomas.
  • The positive rate of SVV in tubular adenomas, villous adenomas, and tubulovillous adenomas were 30% (12/40), 40.9% (9/22), and 35.8% (10/28), respectively.
  • The positive rate of SVV in tubulovillous adenomas with high-grade glandular intraepithelial neoplasia were 68% (17/25).
  • SVV expressions among the three types of adenomas without neoplasia were not significantly different (P > 0.05).
  • SVV expression between each type of the above-mentioned ademoma and tubulovillous adenoma with high-grade glandular intraepithelial neoplasia or different Dukes stages of colorectal carcinoma was significantly different (P < 0.05).
  • SVV expressions in adenocarcinomas and adenomas with high grade glandular intraepithelial neoplasia were significantly higher than those in adenomas (P < 0.01).
  • SVV expression may be useful to distinguish adenocarcinoma from adenoma in colorectal carcinogenesis.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma / metabolism. Colorectal Neoplasms / metabolism. Microtubule-Associated Proteins / biosynthesis

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  • (PMID = 17633470.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / BIRC5 protein, human; 0 / Inhibitor of Apoptosis Proteins; 0 / Microtubule-Associated Proteins
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6. Lane Z, Hansel DE, Epstein JI: Immunohistochemical expression of prostatic antigens in adenocarcinoma and villous adenoma of the urinary bladder. Am J Surg Pathol; 2008 Sep;32(9):1322-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical expression of prostatic antigens in adenocarcinoma and villous adenoma of the urinary bladder.
  • Adenocarcinomas of the bladder are rare, with the diagnosis dependent on exclusion of secondary involvement by direct extension or metastatic spread from other sites.
  • The recent description of an unusual form of urothelial-type mucinous prostatic adenocarcinoma raises a novel differential diagnosis between adenocarcinomas of the prostate and bladder, and investigation into the utility of classic prostatic immunohistochemical antigens in bladder adenocarcinoma is warranted.
  • We identified 37 primary infiltrating adenocarcinomas of the bladder, which included signet ring cell carcinomas (n=11), urachal adenocarcinomas (n=5), and enteric adenocarcinoma (n=21).
  • Also included for comparison were 3 cases, each of bladder villous adenomas and bladder adenocarcinoma in situ.
  • Of the 37 adenocarcinomas, all were negative for PSA and PSAP (0/37; 0%).
  • In contrast, a minority of bladder adenocarcinomas was labeled with the prostate antigens P501S and PSMA.
  • P501S showed moderate diffuse cytoplasmic staining in 4/37 cases (11%), including 3 enteric-type adenocarcinomas and 1 mucinous adenocarcinoma.
  • Additionally, 1 case of adenocarcinoma in situ demonstrated diffuse cytoplasmic staining for P501S.
  • The granular perinuclear staining pattern of P501S typically seen in prostatic adenocarcinoma was absent in all cases of bladder adenocarcinoma.
  • PSMA showed diffuse cytoplasmic staining in 4/37 (11%) infiltrating adenocarcinomas (including 1 signet ring carcinoma and 3 enteric-type adenocarcinomas), and in 1 case of adenocarcinoma in situ.
  • Membranous PSMA staining was evident in an additional 3 tumors, 1 urachal mucinous adenocarcinoma, 1 nonurachal mucinous and signet ring cell adenocarcinoma, and 1 nonurachal villous adenoma.
  • In conclusion, although all cases of bladder adenocarcinoma examined were negative for PSA and PSAP, the surprising finding that a subset of invasive and in situ adenocarcinomas of the bladder demonstrated immunoreactivity for P501S and PSMA should warrant caution when using these markers in differentiating prostatic from bladder adenocarcinomas.
  • The lack of granular perinuclear staining for P501S and the absence of membranous PSMA staining both favor a bladder adenocarcinoma, although rare cases of villous adenoma and adenocarcinoma did show PSMA membranous staining indistinguishable from that seen in prostate cancer.
  • Although the novel antigens P501S and PSMA are fairly specific and more sensitive in the differential diagnosis of prostate and urothelial carcinoma, care must be taken when adenocarcinomas of the bladder are considered within this differential diagnosis.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma, Villous / metabolism. Antigens, Neoplasm / biosynthesis. Urinary Bladder Neoplasms / metabolism
  • [MeSH-minor] Acid Phosphatase. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Membrane Proteins / biosynthesis. Prostate-Specific Antigen / biosynthesis. Prostatic Neoplasms / metabolism. Prostatic Neoplasms / pathology. Protein Tyrosine Phosphatases / biosynthesis. Tissue Array Analysis

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  • (PMID = 18670358.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Membrane Proteins; 0 / prostein; EC 3.1.3.2 / Acid Phosphatase; EC 3.1.3.2 / prostatic acid phosphatase; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.4.21.77 / Prostate-Specific Antigen
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7. Yasugi A, Matsuoka H, Otani H, Maeda K, Matsumoto K, Koda M, Kawaguchi K, Harada K, Yashima K, Murawaki Y, Horie Y: [Case of villous tumor of the rectum presenting with severe diarrhea and electrolyte depletion syndrome]. Nihon Shokakibyo Gakkai Zasshi; 2009 Mar;106(3):377-82
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  • [Title] [Case of villous tumor of the rectum presenting with severe diarrhea and electrolyte depletion syndrome].
  • Colonoscopy revealed large tumor with a villous structure in the rectum.
  • The histopathological diagnosis was adenocarcinoma with villous adenoma.
  • [MeSH-major] Adenoma, Villous / complications. Diarrhea / etiology. Rectal Neoplasms / complications. Water-Electrolyte Imbalance / etiology
  • [MeSH-minor] Adenocarcinoma / complications. Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Aged, 80 and over. Dehydration / etiology. Humans. Male. Neoplasms, Multiple Primary. Severity of Illness Index. Syndrome

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  • (PMID = 19262051.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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8. Beattie GC, Paul I, Calvert CH: Endoscopic transanal resection of rectal tumours using a urological resectoscope--still has a role in selected patients. Colorectal Dis; 2005 Jan;7(1):47-50

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Transanal resection of rectal villous adenomas or adenocarcinomas can be carried out using various modalities such as operative excision, fulguration, laser coagulation or cryotherapy.
  • Histopathology revealed rectal adenoma (with varying degrees of dysplasia) in 11 (55%) patients and adenocarcinoma in 9 (45%).
  • The majority (30; 70%) of resections were carried out in patients with benign disease, with 13 (30%) in patients with rectal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Anal Canal / surgery. Proctoscopy. Rectal Neoplasms / surgery. Urologic Surgical Procedures / instrumentation

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  • (PMID = 15606584.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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9. Lemyé AC, Guy-Viterbo V, van Vyve E: Adenocarcinoma of the duodenum arising in a tubulo-villous adenoma. Acta Chir Belg; 2009 Jan-Feb;109(1):95-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of the duodenum arising in a tubulo-villous adenoma.
  • Villous adenoma of the duodenum is rare and has a high prevalence of cancer.
  • We report here an unusual case of a 73-year-old man who presented with a tumour on the second part of the duodenum with moderate dysplasia of a tubulo-villous adenoma at the biopsies.
  • The final histological analysis was a moderately differentiated invasive duodenal adenocarcinoma (pT3Nx).
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Duodenal Neoplasms / pathology

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  • (PMID = 19341205.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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10. Piana S, Asioli S, Foroni M: Oncocytic adenocarcinoma of the rectum arising on a villous adenoma with oncocytic features. Virchows Arch; 2006 Feb;448(2):228-31
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  • [Title] Oncocytic adenocarcinoma of the rectum arising on a villous adenoma with oncocytic features.
  • Rectal adenocarcinoma with diffuse oncocytic features is a very rare lesion, having been reported only once in the English literature.
  • We describe a case of oncocytic adenocarcinoma of the rectum, associated with a villous adenoma, arising on a 66-year-old man.
  • On histological examination, the adenocarcinoma was composed of neoplastic glands lined by a strongly eosinophilic, granular epithelium that deeply infiltrated the rectal wall.
  • Superficially, a villous adenoma with high-grade dysplasia was evident; adenomatous cells showed focal eosinophilic changes, consisting of a large granular cytoplasm, an oval atypical nucleus, and a prominent nucleolus.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Rectal Neoplasms / pathology

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  • (PMID = 16450120.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CDX2 protein, human; 0 / Carcinoembryonic Antigen; 0 / Homeodomain Proteins; 0 / Keratin-20; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53
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11. Genc H, Haciyanli M, Tavusbay C, Colakoglu O, Aksöz K, Unsal B, Ekinci N: Carcinoma arising from villous adenoma of the ampullary bile duct: Report of a case. Surg Today; 2007;37(2):165-8

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  • [Title] Carcinoma arising from villous adenoma of the ampullary bile duct: Report of a case.
  • Adenocarcinoma arising from the villous adenoma of the ampullary biliary epithelium is an extremely rare disorder.
  • The preoperative diagnosis and treatment of the disease represent a major difficulty.
  • A frozen-section examination of these particles revealed villous adenoma.
  • The frozen-section examination of the resected material also revealed a villous adenoma.
  • The histological examination revealed a villous adenoma arising from the biliary epithelium and some adenocarcinoma foci.
  • This case shows the importance of surgeons to keep in mind the fact that frozen examinations may sometimes miss a malignancy and they therefore cannot be relied upon to rule out malignancy in villous adenoma of the ampullary bile duct.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma, Villous / diagnosis. Ampulla of Vater. Common Bile Duct Neoplasms / diagnosis. Neoplasms, Multiple Primary
  • [MeSH-minor] Aged. Cholangiopancreatography, Endoscopic Retrograde. Cholecystectomy. Diagnosis, Differential. Duodenoscopy. Female. Follow-Up Studies. Humans

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  • (PMID = 17243040.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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12. Zarineh A, Bulakhtina E, Olson PR, Silverman JF: Recurrent villous adenoma with high-grade dysplasia arising in a urethral diverticulum. Case Rep Med; 2009;2009:361212

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  • [Title] Recurrent villous adenoma with high-grade dysplasia arising in a urethral diverticulum.
  • Villous adenomas of the urinary tract are an uncommon, well-recognized entity, described in different locations.
  • We present the first case of a recurrent villous adenoma with high-grade dysplasia unassociated with adenocarcinoma, arising from a urethral diverticulum.
  • There were focal areas with stratification to the luminal surface and loss of nuclear polarity and atypical mitoses, interpreted as villous adenoma with high-grade dysplasia.
  • We also present a brief literature review of urothelial villous adenomas.

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  • [Cites] J Urol. 2008 Dec;180(6):2463-7 [18930487.001]
  • [Cites] Int Urol Nephrol. 2005;37(4):713-5 [16362585.001]
  • [Cites] Mod Pathol. 1999 Jul;12(7):735-8 [10430279.001]
  • [Cites] Am J Surg Pathol. 1999 Jul;23(7):764-71 [10403298.001]
  • [Cites] Urology. 1997 Sep;50(3):427-31 [9301710.001]
  • [Cites] Am J Surg Pathol. 1996 Dec;20(12):1462-8 [8944039.001]
  • [Cites] Chang Gung Med J. 2000 May;23(5):291-5 [10916230.001]
  • [Cites] Cancer. 1984 Dec 1;54(11):2556-63 [6498746.001]
  • [Cites] Urology. 1987 Apr;29(4):446-7 [3564224.001]
  • [Cites] Br J Obstet Gynaecol. 1985 Oct;92(10):1070-1 [4052350.001]
  • [Cites] Am J Clin Pathol. 1983 Jun;79(6):728-31 [6846264.001]
  • [Cites] J Clin Pathol. 2003 Jun;56(6):465-7 [12783975.001]
  • [Cites] Hum Pathol. 2002 Feb;33(2):236-41 [11957151.001]
  • [Cites] Am J Surg Pathol. 1996 Nov;20(11):1346-50 [8898838.001]
  • (PMID = 19718251.001).
  • [ISSN] 1687-9627
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2729294
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13. Tjalma WA, Colpaert CG: Primary vaginal adenocarcinoma of intestinal type arising from a tubulovillous adenoma. Int J Gynecol Cancer; 2006 May-Jun;16(3):1461-5
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  • [Title] Primary vaginal adenocarcinoma of intestinal type arising from a tubulovillous adenoma.
  • Biopsy revealed an adenocarcinoma of the intestinal type, with a small remnant of a villous adenoma.
  • This led to the conclusion that the lesion was a primary intestinal-type adenocarcinoma of the vagina that had arisen from a vaginal villous adenoma.
  • It is important to be aware of this tumor type and to distinguish them from metastatic colorectal adenocarcinoma in order to plan appropriate treatment.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma, Villous / diagnosis. Vaginal Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Intestinal Neoplasms / diagnosis. Middle Aged

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  • (PMID = 16803550.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Uner A, Ebinc FA, Akyurek N, Unsal D, Mentes BB, Dursun A: Vascular endothelial growth factor, c-erbB-2 and c-erbB-3 expression in colorectal adenoma and adenocarcinoma. Exp Oncol; 2005 Sep;27(3):225-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vascular endothelial growth factor, c-erbB-2 and c-erbB-3 expression in colorectal adenoma and adenocarcinoma.
  • METHODS: Sections of adenoma, intramucosal carcinoma and adenocarcinoma were evaluated by immunohistochemistry in 85 malignant and 37 benign colorectal neoplasms for the expression of VEGF, c-erbB-2 and c-erbB-3 considering clinicopathological variables.
  • RESULTS: VEGF was detected in comparable percentages of all neoplasm types while c-erbB-2 expression was detectable more frequently in adenoma than adenocarcinoma cases (65% vs 43%).
  • Except for the correlation of c-erbB-3 expression with Dukes' staging, there was no correlation between the studied markers and grade of differentiation, Dukes' stage and localization of colorectal adenocarcinoma. c-erbB-3 expression was seen more frequently in tubular adenomas, while c-erbB-2 expression was higher in tubulovillous and villous types.
  • [MeSH-major] Adenocarcinoma / genetics. Adenoma / genetics. Colorectal Neoplasms / genetics. Receptor, ErbB-2 / biosynthesis. Receptor, ErbB-3 / biosynthesis. Vascular Endothelial Growth Factor A / biosynthesis

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  • (PMID = 16244586.001).
  • [ISSN] 1812-9269
  • [Journal-full-title] Experimental oncology
  • [ISO-abbreviation] Exp. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ukraine
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A; EC 2.7.10.1 / Receptor, ErbB-2; EC 2.7.10.1 / Receptor, ErbB-3
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15. Kuratate S, Inoue S, Chikakiyo M, Kaneda Y, Harino Y, Hirose T, Yagi T, Saitoh S, Sumitomo M, Fujino R, Satake N: Coexistent poorly-differentiated neuroendocrine cell carcinoma and non-invasive well-differentiated adenocarcinoma in tubulovillous adenoma of the rectum: report of a case. J Med Invest; 2010 Aug;57(3-4):338-44

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  • [Title] Coexistent poorly-differentiated neuroendocrine cell carcinoma and non-invasive well-differentiated adenocarcinoma in tubulovillous adenoma of the rectum: report of a case.
  • Colonoscopy revealed villous tumor covering all the lower rectal lumen.
  • Biopsy yielded a diagnosis of adenoma.
  • Rectosigmoidectomy with lymph node dissection was performed with the diagnosis of rectal cancer that metastasized to the liver.
  • Histological and immuno- histochemical features showed coexistent poorly-differentiated small cell neuroendocrine cell (NEC) carcinoma and non-invasive well-differentiated adenocarcinoma in tubulovillous adenoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Carcinoma, Neuroendocrine / pathology. Neoplasms, Multiple Primary / pathology. Rectal Neoplasms / pathology

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  • (PMID = 20847536.001).
  • [ISSN] 1349-6867
  • [Journal-full-title] The journal of medical investigation : JMI
  • [ISO-abbreviation] J. Med. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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16. Lagarde S, Dauphin M, Delmas C, Vitry F, Bouché O, Thiéfin G, Diebold MD, Cadiot G: Increased risk of colonic neoplasia in patients with sporadic duodenal adenoma. Gastroenterol Clin Biol; 2009 May;33(5):441-5
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  • [Title] Increased risk of colonic neoplasia in patients with sporadic duodenal adenoma.
  • PATIENTS AND METHODS: Rate of colorectal neoplasia in 29 patients with one or more duodenal adenomas were compared with controls matched for gender and age, but without duodenal adenomas (one case to two controls).
  • Neoplastic lesions found at colonoscopy were classified as adenomas, advanced adenomas (size > or =10 mm, villous component, high-grade dysplasia), cancers and advanced neoplasia (cancers and advanced adenomas).
  • Colonoscopy showed at least one adenoma in 15 cases (51.7%) and 11 controls (19%) (P=0.0027; OR 1.87, 1.0-3.49), advanced adenomas in four cases (13.8%) and three controls (5.2%) (NS), and colonic adenocarcinoma in three cases (10.3%) and no controls (0%) (P=0.03).
  • CONCLUSION: Although lacking in statistical power, these results confirm that patients with sporadic duodenal adenoma are at high risk of colonic adenoma and advanced neoplasia, warranting systematic colonoscopy.
  • [MeSH-major] Adenoma / epidemiology. Colonic Neoplasms / epidemiology. Duodenal Neoplasms / epidemiology. Neoplasms, Multiple Primary / epidemiology

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  • (PMID = 19278801.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
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17. Akaydin M, Ersoy YE, Erozgen F, Ferlengez E, Kaplan R, Celik A, Memmi N: Tubulovillous adenoma in the common bile duct causing obstructive jaundice. Acta Gastroenterol Belg; 2009 Oct-Dec;72(4):450-4

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  • [Title] Tubulovillous adenoma in the common bile duct causing obstructive jaundice.
  • Villous adenomas are benign epithelial lesions with a malignant potential which can occur at any site in the gastrointestinal tract, usually in the rectum and colon, less frequently in the small bowel and very rarely in the biliary tract.
  • Villous adenomas of the extrahepatic bile ducts are exceptional and only a few cases have been reported.
  • Common bile duct (CBD) adenomas often present in a fashion similar to their malignant counterparts, and adenocarcinoma arising from a villous adenoma of the ampullary biliary epithelium is also extremely rare.
  • We present here a tubulovillous adenoma, arising in the common bile duct, as a cause of obstructive jaundice, and discuss the characteristics of these lesions.
  • [MeSH-major] Adenoma, Villous / complications. Common Bile Duct Neoplasms / complications. Jaundice, Obstructive / etiology

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  • (PMID = 20163042.001).
  • [ISSN] 1784-3227
  • [Journal-full-title] Acta gastro-enterologica Belgica
  • [ISO-abbreviation] Acta Gastroenterol. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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18. Wang Y, Zhou ZG, Xia QJ, Zhang WY, Li HG, Wang R: [Expression of minichromosome maintenance protein 2 in colonic adenocarcinoma, adenoma and normal colonic mucosa and its clinical significance]. Zhonghua Wei Chang Wai Ke Za Zhi; 2008 Sep;11(5):465-8

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  • [Title] [Expression of minichromosome maintenance protein 2 in colonic adenocarcinoma, adenoma and normal colonic mucosa and its clinical significance].
  • OBJECTIVE: To investigate the expression differences of minichromosome maintenance 2 (MCM2) mRNA and protein among colon adenocarcinoma, colon adenoma and normal mucosa, and among different clinicopathological types of adenomas.
  • METHODS: Fifty specimens, including 33 colonic adenomas, 12 colonic adenocarcinomas and 5 normal colonic mucosa were selected.
  • Expression differences of MCM2 mRNA among the colonic adenocarcinoma, adenoma and normal colonic mucosa were evaluated by REST-XL software.
  • RESULTS: The expression of MCM2 was observed in the basal third to half of the colonic crypts in normal mucosa, while throughout the epithelium in the colonic adenocarcinomas and adenomas.
  • However, the expression of MCM2 mRNA in the adenocarcinomas was significantly higher than that in the adenomas(P=0.001).
  • The MCM2 mRNA expression was elevated in the adenoma with villous type, in the conditions of high-grade dysplasia, larger size, sessile morphology and in patients of older ages, but the difference was not significant by REST-XL (P>0.05).
  • CONCLUSION: The difference of MCM2 expression between the adenoma and the adenocarcinoma indicates its potential value in the early diagnosis of colonic cancer.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma / metabolism. Cell Cycle Proteins / metabolism. Colonic Neoplasms / metabolism. Nuclear Proteins / metabolism

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  • (PMID = 18803052.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cell Cycle Proteins; 0 / Nuclear Proteins; 0 / RNA, Messenger; EC 3.6.4.12 / MCM2 protein, human; EC 3.6.4.12 / Minichromosome Maintenance Complex Component 2
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19. Bosma J, Silvis R: Transanal resection for villous adenomas using the Fansler proctoscope. Acta Chir Belg; 2008 Sep-Oct;108(5):538-41

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  • [Title] Transanal resection for villous adenomas using the Fansler proctoscope.
  • [MeSH-major] Adenoma, Villous / surgery. Proctoscopes. Rectal Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / surgery. Adult. Aged. Aged, 80 and over. Ambulatory Surgical Procedures. Equipment Design. Female. Hospitalization. Humans. Male. Middle Aged. Rectum / surgery

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  • (PMID = 19051462.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Belgium
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20. Nosho K, Yamamoto H, Takamaru H, Hamamoto Y, Goto A, Yoshida Y, Arimura Y, Endo T, Hirata K, Imai K: A case of colorectal carcinoma in adenoma analyzed by a cDNA array. Int J Colorectal Dis; 2005 May;20(3):287-91
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  • [Title] A case of colorectal carcinoma in adenoma analyzed by a cDNA array.
  • Microscopically, the large tumor consisted of a well-differentiated adenocarcinoma with a tubulovillous adenoma (TVA) component (carcinoma in adenoma).
  • Some carcinoma (CA) cells had invaded the submucosal layer, but the lymph nodes were negative for malignancy.
  • K-ras mutation was detected in both CA and TVA lesions of the carcinoma in adenoma.
  • To clarify relevant alterations of gene expression associated with adenoma-carcinoma progression, the gene expression profiles of these tumor tissues were analyzed by a cDNA array.
  • RESULTS: Although the gene expression profiles were similar, insulin-like growth factor-II (IGF-II) was expressed most differentially in CA and TVA tissues.
  • The results were further substantiated by comparison of the gene expression profiles of CA and TVA lesions of the carcinoma in adenoma.
  • CONCLUSION: The results suggest that overexpression of IGF-II played an important role in the progression of adenoma to carcinoma in this patient.
  • [MeSH-major] Adenocarcinoma / genetics. Adenoma, Villous / genetics. Colorectal Neoplasms / genetics. DNA, Complementary / analysis. Neoplasms, Multiple Primary
  • [MeSH-minor] Aged. Biomarkers, Tumor / genetics. Colonoscopy. Diagnosis, Differential. Female. Follow-Up Studies. Gene Expression Regulation, Neoplastic / physiology. Genes, ras / genetics. Humans. Immunohistochemistry. Insulin-Like Growth Factor II / genetics. Mutation. Pedigree. RNA, Messenger / genetics. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 15490195.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Complementary; 0 / RNA, Messenger; 67763-97-7 / Insulin-Like Growth Factor II
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21. Tsuchida K, Morinaga S, Sugano N, Shiozawa M, Akaike M, Sugimasa Y, Takemiya S, Hayashi H, Rino Y, Imada T: [A case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer]. Gan To Kagaku Ryoho; 2006 Nov;33(12):1878-80
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  • [Title] [A case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer].
  • Duodenal adenoma is rare, and there have been very few case reports of flat elevated type adenoma.
  • We report a case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer.
  • Endoscopic examination revealed the gastric cancer and a flat elevated tumor in the descending part of the duodenum, measuring 6 cm in diameter.
  • The biopsy specimen of the duodenal lesion was diagnosed as adenoma.
  • Histologically, the gastric cancer was poorly differentiated adenocarcinoma with submcosal invasion and without lymph node metastasis, and the duodenal tumor was a well differentiated carcinoma in villous adenoma.
  • The duodenal adenocarcinoma was limited to the mucosal layer and the resected margins were free of tumor.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Carcinoma / pathology. Duodenal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Stomach Neoplasms / pathology

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  • (PMID = 17212134.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 4
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22. Mizoshita T, Tsukamoto T, Inada KI, Hirano N, Tajika M, Nakamura T, Ban H, Tatematsu M: Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon. Histol Histopathol; 2007 03;22(3):251-60
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  • [Title] Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon.
  • MUC2 expression demonstrated a significant decrease from tubular/tubulovillous adenomas with moderate atypia, through intramucosal carcinomas, to cancers with submucosal invasion (P<0.0001).
  • Intramucosal de novo carcinomas (flat type carcinomas without adenomatous components) exhibited a greater decrease of MUC2 than intramucosal lesions with adenomatous components.
  • Expression of MUC5AC also decreased significantly with progression according to the tubular/tubulovillous adenoma-carcinoma sequence, carcinomas with villous adenomatous components having a higher level compared with their tubular adenomatous counterparts, suggesting differences in the pathway of malignant transformation.
  • Cdx2 nuclear expression was maintained in all of the adenomas and early carcinomas examined.
  • CONCLUSIONS: Our data suggest that the reduction of MUC2 expression may be associated with the occurrence and progression of colorectal carcinomas in both adenoma-carcinoma sequence pathway and de novo carcinogenesis.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma, Villous / metabolism. Colorectal Neoplasms / metabolism. Mucins / metabolism

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  • (PMID = 17163399.001).
  • [ISSN] 1699-5848
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CDX2 Transcription Factor; 0 / CDX2 protein, human; 0 / Homeodomain Proteins; 0 / MUC2 protein, human; 0 / MUC5AC protein, human; 0 / MUC6 protein, human; 0 / Microfilament Proteins; 0 / Mucin 5AC; 0 / Mucin-2; 0 / Mucin-6; 0 / Mucins; 0 / villin
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23. Kim HC, Roh SA, Ga IH, Kim JS, Yu CS, Kim JC: CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer. J Gastroenterol Hepatol; 2005 Dec;20(12):1920-6
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  • [Title] CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer.
  • We evaluated the methylation status of primary colorectal tumors to determine its role in the adenoma to carcinoma sequence.
  • METHODS: The methylation status of APC, THBS1, MGMT, hMLH1 and GSTP1, as determined by methylation specific PCR (MSP), and microsatellite instability (MSI) using three mononucleotide markers were assessed in 40 colorectal adenomas and 36 adenocarcinomas.
  • RESULTS: Of the 40 adenomas, 24 (60%) were methylated at one or more loci, and 12 (30%) at two or more loci (CpG island methylation phenotype-high, CIMP-H).
  • THBSI was the most frequently methylated locus in both adenomas (n = 19, 47.5%) and carcinomas (n = 16, 44.4%).
  • Overall, methylation status of adenomas and carcinomas did not differ significantly (P = 0.53), nor did the methylation status of individual genes.
  • For adenomas, size (P = 0.049) and histologic classification of the villous components (P = 0.018) were each associated with methylation status.
  • MSI was detected in three adenomas (7.5%) and five carcinomas (13.9%), and was closely correlated with hMLH1 methylation (P < 0.001).
  • CONCLUSIONS: In colorectal tumors, CpG island methylation of tumor suppressor genes appears to be common and may be involved in the progression of adenomas.
  • [MeSH-major] Adenocarcinoma / genetics. Adenoma / genetics. Cell Transformation, Neoplastic / genetics. Colorectal Neoplasms / genetics. CpG Islands / genetics. DNA Methylation

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  • [Copyright] Copyright 2005 Blackwell Publishing Asia Pty Ltd.
  • [ErratumIn] J Gastroenterol Hepatol. 2005 Dec;20(12):1951
  • (PMID = 16336454.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
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24. Bodin R, Peycru T, Schwartz A, Jarry J, Pommier N, Durand-Dastes F: Tubulovillous adenoma of the appendix: a case report and review of the literature. Gastroenterol Clin Biol; 2010 Nov;34(11):633-5

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  • [Title] Tubulovillous adenoma of the appendix: a case report and review of the literature.
  • The histological examination of the resected specimen revealed a rare tumor: tubulovillous adenoma, discovered in 0.02% of all appendectomy procedures.
  • Treatment is most often limited to appendectomy, but in the event of incomplete excision or associated adenocarcinoma, right hemicolectomy may be required.
  • [MeSH-major] Adenoma, Villous / surgery. Appendectomy. Appendiceal Neoplasms / surgery

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20739133.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] France
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25. Fancher TT, Dudrick SJ, Palesty JA: Papillary adenocarcinoma of the urachus presenting as an umbilical mass. Conn Med; 2010 Jun-Jul;74(6):325-7

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  • [Title] Papillary adenocarcinoma of the urachus presenting as an umbilical mass.
  • The patient subsequently underwent a cystoscopic biopsy which was positive for papillary adenocarcinoma arising in a villous adenoma.
  • [MeSH-major] Adenocarcinoma, Papillary / pathology. Urachus / pathology

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  • (PMID = 20648839.001).
  • [ISSN] 0010-6178
  • [Journal-full-title] Connecticut medicine
  • [ISO-abbreviation] Conn Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Wang LP, Chen J, Ning HY, Zhang XZ, Cheng J, Li L, Wang B, Dai XJ, Zhu HY, Miao JH, Wang L: [Serrated lesions of colon and their malignant potential]. Zhonghua Bing Li Xue Za Zhi; 2010 Jul;39(7):447-51
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  • OBJECTIVE: To study the serrated lesions of colon and to compare the malignant potential between traditional serrated adenomas (TSA) and conventional adenomas (CAD).
  • One hundred and eighty-seven cases of CAD (including 160 cases of tubular adenoma and 27 cases of villous adenoma) and 36 cases of invasive adenocarcinoma were randomly selected as the controls.
  • RESULTS: Amongst the 5347 colorectal polyps studied, 258 cases (4.8%) of serrated lesions were found, which included 112 cases (43.4%, 112/258) of hyperplastic polyp, 78 cases (30.2%, 78/258) of TSA and 26 cases (10.1%, 26/258) of sessile serrated adenoma.
  • Compared with the 187 cases of CAD, moderate dysplasia were found in 27 cases and high-grade intraepithelial neoplasia and invasive adenocarcinoma were found in 25 cases (13.3%, χ(2) = 19.373, P = 0.000).
  • TSA has obvious malignant potential; but the rate associated with high-grade intraepithelial neoplasia and invasive adenocarcinoma is lower than that in CAD.
  • [MeSH-major] Adenoma / pathology. Cell Transformation, Neoplastic / pathology. Colorectal Neoplasms / pathology. Intestinal Polyps / pathology
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenoma, Villous / classification. Adenoma, Villous / metabolism. Adenoma, Villous / pathology. Colonic Polyps / metabolism. Colonic Polyps / pathology. Humans. Ki-67 Antigen / metabolism. Precancerous Conditions / metabolism. Precancerous Conditions / pathology. Rectum / pathology. Retrospective Studies. Tumor Suppressor Protein p53 / metabolism. beta Catenin / metabolism

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  • (PMID = 21055172.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53; 0 / beta Catenin
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27. Osunkoya AO, Epstein JI: Primary mucin-producing urothelial-type adenocarcinoma of prostate: report of 15 cases. Am J Surg Pathol; 2007 Sep;31(9):1323-9
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  • [Title] Primary mucin-producing urothelial-type adenocarcinoma of prostate: report of 15 cases.
  • Prostatic urothelial-type adenocarcinoma arises through a process of glandular metaplasia of the prostatic urethral urothelium and subsequent in situ adenocarcinoma sometimes associated with villous adenoma.
  • These prostatic adenocarcinomas are analogous to nonurachal adenocarcinomas arising in the bladder from cystitis glandularis.
  • Only 2 cases of urothelial-type adenocarcinoma from an institution other than our own have been previously described.
  • The distinction between adenocarcinoma from another organ secondarily involving the prostate, usual adenocarcinoma of the prostate, and prostatic urothelial-type adenocarcinoma can present a significant diagnostic challenge and has significant therapeutic implications.
  • Fifteen cases of prostatic urothelial-type adenocarcinoma were retrieved from the consult files of one of the authors.
  • Mean patient age at diagnosis was 72 years (range 58 to 93 y).
  • In 8/15 (53%) cases, glandular metaplasia of the prostatic urethra and contiguous transition to adenocarcinoma were identified.
  • Multiple histologic patterns were observed including dissection of the stroma by mucin pools 15/15 (100%), villous features 7/15 (47%), necrosis 2/15 (13.3%), signet ring cells 3/15 (20%), perineural invasion 1/15 (6.7%), focal squamous differentiation 1/15 (6.7%), and a granulomatous inflammatory response 1/15 (6.7%).
  • Prostatic urothelial-type adenocarcinoma is a rare aggressive cancer arising in the prostate.
  • The differential diagnosis includes conventional prostatic mucinous adenocarcinoma and secondary infiltration from a colonic or bladder adenocarcinoma.
  • Immunohistochemistry for prostate specific antigen, prostate specific acid phosphatase, and high molecular weight cytokeratin along with morphology can help rule out conventional prostate carcinoma. beta-catenin, CDX2, and clinical studies are needed to rule out colonic adenocarcinoma.
  • As prostatic urothelial-type adenocarcinoma is entirely analogous to bladder adenocarcinoma in both, its morphology and immunophenotype, only clinical studies or in some cases pathologic examination of the cystoprostatectomy specimen can exclude infiltration from a primary bladder adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma, Mucinous / diagnosis. Mucins / analysis. Prostatic Neoplasms / diagnosis. Urothelium / pathology
  • [MeSH-minor] Acid Phosphatase. Aged. Aged, 80 and over. Cell Differentiation. Diagnosis, Differential. Follow-Up Studies. Homeodomain Proteins / analysis. Humans. Immunohistochemistry. Keratin-20 / analysis. Keratin-7 / analysis. Male. Middle Aged. Neoplasm Invasiveness. Prognosis. Prostate-Specific Antigen / analysis. Protein Tyrosine Phosphatases / analysis. Time Factors. beta Catenin / analysis

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  • (PMID = 17721186.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CDX2 protein, human; 0 / CTNNB1 protein, human; 0 / Homeodomain Proteins; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 0 / Mucins; 0 / beta Catenin; EC 3.1.3.2 / Acid Phosphatase; EC 3.1.3.2 / prostatic acid phosphatase; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.4.21.77 / Prostate-Specific Antigen
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28. Van Kerkhóve F, Coenegrachts K, Steyaert L, Van Den Berghe I, Casselman JW: Collision tumor in the ileum: a rare combination of an adenocarcinoma and small cell neuroendocrine tumor. JBR-BTR; 2006 Sep-Oct;89(5):258-60
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  • [Title] Collision tumor in the ileum: a rare combination of an adenocarcinoma and small cell neuroendocrine tumor.
  • Ultrasound examination discovered an inhomogeneous vascularised mass originating from a small bowel loop, mesenteric enlarged lymph nodes and a nodule in the liver.
  • Pathology revealed a rare ileal collision tumor consisting of an adenocarcinoma and a small cell neuroendocrine tumor with peritoneal metastasis of neuroendocrine origin and coincidental benign lesions on both ovaries.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma, Villous / diagnosis. Adenomatous Polyps / diagnosis. Carcinoma, Small Cell / diagnosis. Ileal Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Tomography, X-Ray Computed. Ultrasonography
  • [MeSH-minor] Adenofibroma / diagnosis. Adenofibroma / pathology. Adenofibroma / surgery. Aged. Cystadenoma / diagnosis. Cystadenoma / pathology. Cystadenoma / surgery. Female. Fibroma / diagnosis. Fibroma / pathology. Fibroma / surgery. Humans. Ileum / pathology. Ileum / surgery. Intestinal Mucosa / pathology. Intestinal Mucosa / surgery. Liver / pathology. Liver / surgery. Lymphatic Metastasis / pathology. Mesentery / pathology. Mesentery / surgery. Omentum / pathology. Omentum / surgery. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / pathology. Ovarian Neoplasms / surgery. Ovariectomy. Ovary / pathology. Peritoneum / pathology. Peritoneum / surgery

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  • (PMID = 17147014.001).
  • [ISSN] 0302-7430
  • [Journal-full-title] JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)
  • [ISO-abbreviation] JBR-BTR
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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29. Sayles M, Courtney E, Younis F, O'Donovan M, Ibrahim A, Fearnhead NS: Appendiceal mucinous adenocarcinoma presenting as an enterocutaneous fistula in an incisional hernia. BMJ Case Rep; 2010;2010
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  • [Title] Appendiceal mucinous adenocarcinoma presenting as an enterocutaneous fistula in an incisional hernia.
  • Histological evaluation confirmed a well-to-moderately differentiated mucinous adenocarcinoma arising on a background of dysplastic villous adenoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Appendiceal Neoplasms / diagnosis. Bone Transplantation. Hernia, Abdominal / diagnosis. Ilium / surgery. Intestinal Fistula / diagnosis. Postoperative Complications / diagnosis. Tissue and Organ Harvesting
  • [MeSH-minor] Abdominal Abscess / diagnosis. Aged. Appendectomy. Colectomy. Female. Humans. Laparoscopy. Lymph Node Excision. Neoplasm Staging. Reoperation

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  • [Cites] Cancer. 1973 Dec;32(6):1525-41 [4757938.001]
  • [Cites] Actas Urol Esp. 2004 Apr;28(4):327-31 [15248407.001]
  • [Cites] J Dermatol. 1987 Apr;14(2):167-9 [3038981.001]
  • [Cites] Dis Colon Rectum. 1988 Feb;31(2):145-50 [3276467.001]
  • [Cites] Surg Gynecol Obstet. 1988 May;166(5):451-3 [2452489.001]
  • [Cites] Semin Oncol. 1988 Apr;15(2):129-37 [3285476.001]
  • [Cites] J R Soc Med. 1988 Nov;81(11):668-9 [3210202.001]
  • [Cites] Surgery. 1992 Mar;111(3):244-50 [1542852.001]
  • [Cites] Cancer. 1992 Jul 15;70(2):396-401 [1319813.001]
  • [Cites] Ann Surg. 1994 Jan;219(1):51-7 [8297177.001]
  • [Cites] Dis Colon Rectum. 1995 Aug;38(8):848-52 [7634979.001]
  • [Cites] Dis Colon Rectum. 1998 Jan;41(1):75-80 [9510314.001]
  • [Cites] Am J Gastroenterol. 1998 Mar;93(3):422-8 [9517651.001]
  • [Cites] Abdom Imaging. 1999 Mar-Apr;24(2):193-5 [10024411.001]
  • [Cites] Am J Proctol. 1963 Dec;14:265-81 [14098730.001]
  • [Cites] Surg Today. 2007;37(9):806-10 [17713739.001]
  • [Cites] Postgrad Med. 2008 Nov;120(4):95-100 [19020371.001]
  • [Cites] Am J Surg Pathol. 2009 Feb;33(2):248-55 [18852679.001]
  • [Cites] Cancer J. 2009 May-Jun;15(3):225-35 [19556909.001]
  • [Cites] Int J Urol. 2001 Apr;8(4):196-8 [11260355.001]
  • [Cites] Arch Esp Urol. 2001 Jun;54(5):451-4 [11494721.001]
  • [Cites] J Int Med Res. 2002 Jul-Aug;30(4):452-6 [12235932.001]
  • [Cites] Hepatogastroenterology. 2003 Mar-Apr;50(50):432-7 [12749241.001]
  • [Cites] AJR Am J Roentgenol. 1985 May;144(5):923-9 [3885692.001]
  • (PMID = 22789695.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3038038
  •  go-up   go-down


30. Fu KI, Hamahata Y, Tsujinaka Y: Early colon cancer within a diverticulum treated by magnifying chromoendoscopy and laparoscopy. World J Gastroenterol; 2010 Mar 28;16(12):1545-7
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  • We report a unique case of intramucosal carcinoma in a tubulovillous adenoma arising from a single diverticulum.
  • Histologically, the resected lesion was an intramucosal well-differentiated adenocarcinoma and the surgical margin was free of tumor.
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Colectomy. Colonic Neoplasms / surgery. Colonic Polyps / surgery. Colonoscopy / methods. Diverticulum, Colon / complications. Laparoscopy

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  • [Cites] J Gastroenterol. 1999 Oct;34(5):622-5 [10535492.001]
  • [Cites] Endoscopy. 2001 Apr;33(4):306-10 [11315890.001]
  • [Cites] Dis Colon Rectum. 1974 Mar-Apr;17(2):258-61 [4819277.001]
  • [Cites] Dis Colon Rectum. 1975 Jan-Feb;18(1):49-51 [165048.001]
  • [Cites] Dis Colon Rectum. 1976 Sep;19(6):553-56 [964114.001]
  • [Cites] Am J Gastroenterol. 2008 Nov;103(11):2700-6 [18853968.001]
  • [Cites] Surgery. 1993 Feb;113(2):223-6 [8430371.001]
  • [Cites] Pathol Int. 1996 Jul;46(7):538-9 [8870012.001]
  • [Cites] J Gastrointest Surg. 2007 May;11(5):655-9 [17468926.001]
  • [Cites] J Gastroenterol Hepatol. 2007 Sep;22(9):1409-14 [17593224.001]
  • [Cites] Endoscopy. 2008 Sep;40 Suppl 2:E44 [18300202.001]
  • [Cites] AJR Am J Roentgenol. 1992 Dec;159(6):1348 [1442418.001]
  • (PMID = 20333800.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2846265
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31. Terhaar sive Droste JS, van Wanrooij RL, Morsink LM, van der Hulst RW, Craanen ME, Bartelsman JW, Meijer GA, Mulder CJ: [Diagnosis of colorectal tumours in daily clinical practice: comparison of colonoscopy and sigmoidoscopy]. Ned Tijdschr Geneeskd; 2009;153:A731
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  • [Title] [Diagnosis of colorectal tumours in daily clinical practice: comparison of colonoscopy and sigmoidoscopy].
  • [Transliterated title] Diagnostiek van colorectale tumoren in de dagelijkse praktijk. Vergelijking van coloscopie en sigmoïdoscopie.
  • Advanced neoplasm was defined as adenoma >or=10 mm in size, an adenoma with any villous features, or high-grade dysplasia or adenocarcinoma.
  • [MeSH-major] Colonoscopy. Colorectal Neoplasms / diagnosis. Sigmoidoscopy

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  • (PMID = 20003556.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Multicenter Study
  • [Publication-country] Netherlands
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32. Sohn JW, Jeon SW, Cho CM, Jung MK, Kim SK, Lee DS, Son HS, Chung IK: Endoscopic resection of duodenal neoplasms: a single-center study. Surg Endosc; 2010 Dec;24(12):3195-200
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  • BACKGROUND: Premalignant duodenal lesions such as adenomas are rare.
  • METHODS: Patients with nonampullary duodenal adenomas or duodenal adenocarcinomas without familial polyposis syndrome between August 2002 and February 2009 were retrospectively analyzed.
  • Of these patients, 23 had duodenal adenomas and 1 had an adenocarcinoma confined to the mucosa.
  • Tubular adenomas were the most common type (17/24, 70.8%).
  • There were four cases of the villotubular type and three of the villous type.
  • During the short-term follow-up evaluation, EMR showed outcomes and complications comparable with prior procedures, including adenocarcinomas confined to the mucosa.
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma / surgery. Duodenal Neoplasms / surgery. Duodenoscopy

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  • (PMID = 20490557.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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33. Khan MN, Moran BJ: Four percent of patients undergoing colorectal cancer surgery may have synchronous appendiceal neoplasia. Dis Colon Rectum; 2007 Nov;50(11):1856-9
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  • The appendix has a similar mucosal pattern to the colon and it has been hypothesized that appendicular adenocarcinoma may account for 1 percent of all colorectal malignancies.
  • Seven of 169 appendices had abnormalities: 3 mucinous cystadenomas, 2 cystadenocarcinomas, 1 carcinoid tumor, and 1 villous adenoma.
  • CONCLUSIONS: Patients having colorectal cancer resection for adenocarcinoma should have appendicectomy performed.
  • [MeSH-major] Adenocarcinoma / epidemiology. Appendiceal Neoplasms / epidemiology. Colorectal Neoplasms / epidemiology. Neoplasms, Multiple Primary / epidemiology

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  • (PMID = 17763906.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Selcuk H, Korkmaz M, Kanbay M, Tore E, Sumer H, Unal H, Yeloglu O, Gur G, Bilezikci B, Demirhan B, Yilmaz U, Boyacioglu S: Total colonic polyp diameter: a marker for the risk of malignancy? Hepatogastroenterology; 2008 May-Jun;55(84):936-9
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  • The polyps were further categorized by histopathologic component as "unfavorable" or "favorable" and were divided into 2 groups: group 1 (those identified as carci noma, carcinoma in situ, villous adenoma, and tubulovillous adenoma with a villous component of more than 25%) and group 2 (mixed adenomatous polyps with various degrees of hyperplastic or inflammatory components and adenomas with a tubular component of more than 75%).
  • [MeSH-minor] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Adenomatous Polyps / pathology. Adult. Aged. Aged, 80 and over. Carcinoma in Situ / pathology. Colonoscopy. Female. Humans. Male. Middle Aged. Prognosis. Risk Factors

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  • (PMID = 18705301.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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35. Kohashi T, Itamoto T, Yamasaki H, Yokoya H, Yonehara S, Asahara T: Sciatic hernia with an early-stage adenocarcinoma of the appendix: report of a case. Hiroshima J Med Sci; 2006 Sep;55(3):93-5

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  • [Title] Sciatic hernia with an early-stage adenocarcinoma of the appendix: report of a case.
  • Sciatic hernia and early-stage appendiceal adenocarcinoma are rare disorders.
  • We report herein a case of an early stage of appendiceal adenocarcinoma found incidentally during an operation for sciatic hernia.
  • Abdominal computed tomography showed a small bowel obstruction and a small bowel loop through the right sciatic foramen outside the pelvic cavity.
  • During an operation for the repair of the sciatic hernia, a deformed appendix was found incidentally and a simple appendectomy was also performed.
  • Histological examination of the excised appendix showed well-differentiated adenocarcinoma confined to the mucosal layer in a tubulo-villous adenoma.
  • [MeSH-major] Adenocarcinoma / surgery. Appendiceal Neoplasms / surgery. Herniorrhaphy

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  • (PMID = 16995495.001).
  • [ISSN] 0018-2052
  • [Journal-full-title] Hiroshima journal of medical sciences
  • [ISO-abbreviation] Hiroshima J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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36. Terkivatan T, den Hoed PT, Lange JF Jr, Koot VC, van Goch JJ, Veen HF: The place of the posterior surgical approach for lesions of the rectum. Dig Surg; 2005;22(1-2):86-90

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  • RESULTS: Twenty-eight men and 29 women with a mean age of 70.5 (range 47-83) years underwent either a posterior transsacral (n = 52) or a transsphincteric (n = 5) procedure.
  • Indications for surgery were benign lesions (n = 33), e.g. villous adenoma, rectal prolapse and endometriosis as well as invasive adenocarcinoma (n = 24).
  • All patients with an invasive adenocarcinoma were classified as ASA grade III or IV.
  • During a mean follow-up of 29 (range 2-86) months, 3 patients with a villous adenoma and 2 patients who were treated for a malignant lesion had a locally recurrent lesion.
  • [MeSH-minor] Adenoma, Villous / surgery. Aged. Aged, 80 and over. Endometriosis / surgery. Female. Humans. Male. Middle Aged. Prolapse. Rectal Diseases / surgery

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  • (PMID = 15849468.001).
  • [ISSN] 0253-4886
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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37. Burbos N, Giarenis I, Ostrowski J, Lonsdale R, Nieto JJ: Synchronous diagnosis of multiple tumours in a postmenopausal woman. Arch Gynecol Obstet; 2009 Oct;280(4):627-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous diagnosis of multiple tumours in a postmenopausal woman.
  • Serum CA-125 level was elevated at 8,985 kU/l (normal range 0-35).
  • Histopathology showed a Grade 3 endometrial adenocarcinoma.
  • Both ovaries were completely replaced by partially necrotic poorly differentiated endometrioid adenocarcinoma.
  • Small deposits of metastatic adenocarcinoma were seen within the omentum.
  • A large polypoid tumour within the right colon was a tubulo-villous adenoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Colonic Neoplasms / diagnosis. Genital Neoplasms, Female / diagnosis. Liposarcoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Retroperitoneal Neoplasms / diagnosis

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  • (PMID = 19198863.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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38. Sanford MF, Pickhardt PJ: Diagnostic performance of primary 3-dimensional computed tomography colonography in the setting of colonic diverticular disease. Clin Gastroenterol Hepatol; 2006 Aug;4(8):1039-47
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  • [MeSH-major] Colonography, Computed Tomographic. Diverticulosis, Colonic / diagnosis. Imaging, Three-Dimensional
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenoma, Villous / diagnosis. Colonic Neoplasms / diagnosis. Colonic Polyps / diagnosis. Colonoscopy. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prospective Studies. Sensitivity and Specificity

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  • (PMID = 16793347.001).
  • [ISSN] 1542-3565
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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39. Wang LP, Yang GZ, Zhou ZY, Li L, Gao BL, Chen J: [Clinicopathologic features and proliferative status of colorectal serrated lesions: a study of 104 cases]. Zhonghua Bing Li Xue Za Zhi; 2009 Feb;38(2):100-5
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  • OBJECTIVE: To study the clinicopathologic features and proliferative status of colorectal hyperplastic polyp (HP), sessile serrated adenoma (SSA) and traditional serrated adenoma (TSA).
  • RESULTS: On the basis of morphologic examination, 60 cases were classified as HP, 20 cases as TSA, 11 cases as SSA, 7 cases as mixed HP/SSA/TSA, and 6 cases as mixed serrated polyp/adenoma and tubular adenoma.
  • The number and distribution of Ki-67 positive cells in SSA were similar to those in TSA but were significantly different from those in tubular adenoma and adenocarcinoma (chi2=34.601, P=0.000; chi2=63.077, P=0.000, respectively).
  • CONCLUSIONS: HP, SSA and TSA have their morphologic characteristics, with some overlapping features noted.
  • Diagnosis of SSA relies mostly on architectural rather than cytologic features.
  • In general, the proliferative index is lower in serrated adenoma (TSA or SSA) than in tubular adenoma.
  • [MeSH-major] Adenoma / pathology. Colorectal Neoplasms / pathology. Intestinal Polyps / pathology. Ki-67 Antigen / metabolism
  • [MeSH-minor] Adenocarcinoma / pathology. Adenoma, Villous / metabolism. Adenoma, Villous / pathology. Adult. Aged. Aged, 80 and over. Cell Proliferation. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 19573354.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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40. Zhou ZY, Han Y, Wang LP: [BRAF mutation in colorectal serrated lesions]. Zhonghua Yi Xue Za Zhi; 2008 Dec 30;88(48):3411-4
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  • OBJECTIVE: To investigate the viral oncogene homolog B1 (BRAF) mutation frequency in serrated colorectal adenocarcinoma (Sca), and to verify the existence of a new serrated pathway indirectly.
  • METHODS: 75 paraffin-embedded tissue samples, including 15 cases of Sca, 20 cases of traditional serrated adenoma (TSA), 20 cases of non-serrated adenocarcinoma (NS-ca), and 20 cases of villous adenoma, were reviewed.
  • However, no BRAF V600E mutation was found in the 14 NS-ca samples and the 11 villous adenoma specimens.
  • The BRAF V600E mutation frequencies of the villous adenoma group and NS-ca group were significantly lower than those of the TSA group and Sca group (P = 0.0084); however, there was no statistical difference in the frequency of BRAF V600E mutation between the Sca and TSA groups (P > 0.05).
  • CONCLUSION: BRAF V600E mutation frequency is significantly higher in the Sca and TSA patients than in the NS-ca and villous adenoma patients.
  • There is actually a new serrated neoplasia pathway different from the traditional adenoma-carcinoma carcinogenesis pathway.
  • [MeSH-major] Adenocarcinoma / genetics. Adenoma / genetics. Colorectal Neoplasms / genetics. Proto-Oncogene Proteins B-raf / genetics

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  • (PMID = 19159571.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
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41. John R, El-Rouby NM, Tomasetto C, Rio MC, Karam SM: Expression of TFF3 during multistep colon carcinogenesis. Histol Histopathol; 2007 07;22(7):743-51
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  • Colonic tissues representing colitis, adenomatous polyposis, tubulovillous adenoma, and mucoid/adeno-carcinomas were processed for immunohistochemistry using an antibody specific for human TFF3.
  • The data showed marked down-regulation of TFF3 expression in adenomatous polyposis, then TFF3 expression returns to about control level during adenoma and remains high during mucoid- and adeno-carcinomas.
  • [MeSH-major] Adenocarcinoma, Mucinous / chemistry. Adenoma, Villous / chemistry. Adenomatous Polyposis Coli / chemistry. Colitis / metabolism. Colonic Neoplasms / chemistry. Peptides / analysis

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  • (PMID = 17455148.001).
  • [ISSN] 1699-5848
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Peptides; 0 / Proliferating Cell Nuclear Antigen; 0 / TFF3 protein, human; 0 / Trefoil Factor-3
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42. Lin GL, Meng WC, Lau PY, Qiu HZ, Yip AW: Local resection for early rectal tumours: Comparative study of transanal endoscopic microsurgery (TEM) versus posterior trans-sphincteric approach (Mason's operation). Asian J Surg; 2006 Oct;29(4):227-32
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  • METHODS: The study group comprised 31 consecutive patients with early rectal tumours (18 villous adenomas, 13 adenocarcinomas) who underwent TEM in Kwong Wah Hospital, Hong Kong.
  • The control group consisted of 51 patients with early rectal tumours (27 villous adenomas, 24 adenocarcinomas) who underwent Mason's operation in Peking Union Medical College Hospital, Beijing.

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  • (PMID = 17098653.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] China
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43. Schneider AR, Seifert H, Trojan J, Stein J, Hoepffner NM: Frequency of colorectal polyps in patients with sporadic adenomas or adenocarcinomas of the papilla of vater--an age-matched, controlled study. Z Gastroenterol; 2005 Oct;43(10):1123-7

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  • [Title] Frequency of colorectal polyps in patients with sporadic adenomas or adenocarcinomas of the papilla of vater--an age-matched, controlled study.
  • METHODS: 26 consecutive patients (16 women, 10 men; median age 59 years) with sporadic adenomas (n = 19) or adenocarcinomas (n = 7) of the ampulla of Vater were retrospectively evaluated.
  • [MeSH-major] Adenocarcinoma / complications. Adenoma / complications. Ampulla of Vater. Common Bile Duct Neoplasms / complications. Intestinal Polyps / epidemiology
  • [MeSH-minor] Adenoma, Villous / complications. Adenoma, Villous / surgery. Adenomatous Polyposis Coli / epidemiology. Adult. Aged. Aged, 80 and over. Colonic Polyps / diagnosis. Colonic Polyps / epidemiology. Colonoscopy. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / epidemiology. Data Interpretation, Statistical. Female. Follow-Up Studies. Humans. Male. Middle Aged. Prevalence. Retrospective Studies. Risk Factors. Time Factors

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  • (PMID = 16220451.001).
  • [ISSN] 0044-2771
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
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44. Gracia Solanas JA, Ramírez Rodríguez JM, Aguilella Diago V, Elía Guedea M, Martínez Díez M: A prospective study about functional and anatomic consequences of transanal endoscopic microsurgery. Rev Esp Enferm Dig; 2006 Apr;98(4):234-40
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  • INTRODUCTION: transanal endoscopic microsurgery (TEM) was developed in 1983 by Büess as a minimally invasive technique to manage rectal villous adenomas and early rectal adenocarcinomas.
  • RESULTS: 32 patients (80%) had villous adenomas and 8 patients (20%) had adenocarcinomas (uT1).
  • CONCLUSIONS: during TEM, a significant anal dilatation occurs, because of rectoscopy (40 mm wide), what can produce a rupture of IAS, with the consequent decreasing in ARP, and a dilatation without rupture of external sphincter what produces a decreasing of MSP.
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Microsurgery / methods. Proctoscopy. Rectal Neoplasms / surgery

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  • (PMID = 16792452.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] eng; spa
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
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45. Bini EJ, Green B, Poles MA: Screening colonoscopy for the detection of neoplastic lesions in asymptomatic HIV-infected subjects. Gut; 2009 Aug;58(8):1129-34
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  • BACKGROUND: Although non-AIDS defining malignancies are rapidly increasing as HIV-infected subjects live longer, little is know about the results of screening for colonic neoplasms (adenomatous polyps and adenocarcinomas) in this population.
  • Advanced neoplasms were defined as adenomas >or=10 mm or any adenoma, regardless of size, with villous histology, high-grade dysplasia, or adenocarcinoma.
  • Among patients with colorectal adenocarcinoma, HIV-infected subjects were significantly younger (52.4 (SD 1.3) vs 60.3 (SD 4.0) years, p = 0.002) and were more likely to have advanced cancers (stage III or IV) than control subjects (60.0% vs 16.7%, p = 0.24).
  • CONCLUSIONS: HIV-infected subjects have a higher prevalence of colonic neoplasms, and adenocarcinomas develop at a younger age and are more advanced than in uninfected subjects.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Colonic Neoplasms / diagnosis. HIV Infections / complications

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  • (PMID = 19293177.001).
  • [ISSN] 1468-3288
  • [Journal-full-title] Gut
  • [ISO-abbreviation] Gut
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
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46. Schiessel R, Novi G, Holzer B, Rosen HR, Renner K, Hölbling N, Feil W, Urban M: Technique and long-term results of intersphincteric resection for low rectal cancer. Dis Colon Rectum; 2005 Oct;48(10):1858-65; discussion 1865-7
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  • RESULTS: One hundred seventeen patients had rectal cancers, two had dysplastic villous adenomas, and two had carcinoid tumors.
  • Postoperative complications were: one death because of pulmonary embolism, 5.1 percent developed an anastomotic fistula, one patient had a fistula to the bladder requiring reoperation, one patient with ileus needed relaparotomy as well as one for intra-abdominal hemorrhage and a small-bowel fistula.
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Anal Canal / surgery. Carcinoid Tumor / surgery. Colectomy / methods. Rectal Neoplasms / surgery

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  • (PMID = 16086223.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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47. Wasilewicz MP, Kołodziej B, Bojułko T, Kaczmarczyk M, Sulzyc-Bielicka V, Bielicki D, Ciepiela K: Overexpression of 5-lipoxygenase in sporadic colonic adenomas and a possible new aspect of colon carcinogenesis. Int J Colorectal Dis; 2010 Sep;25(9):1079-85
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  • [Title] Overexpression of 5-lipoxygenase in sporadic colonic adenomas and a possible new aspect of colon carcinogenesis.
  • Our purpose was to investigate the possible connection between 5-LOX expression and colon carcinogenesis by characterizing 5-LOX expression in histologically different colonic adenomas, determining the relationship between high expression of 5-LOX and various conventional clinicopathological features of adenomas, and finally characterizing the histological localization of cells with 5-LOX overexpression.
  • METHODS: A total of 111 patients were examined and 120 histologically different colonic adenomas analyzed (including four cases of intramucosal adenocarcinoma in a polyp).
  • RESULTS: There was a significant correlation between high 5-LOX expression and patient age, increased polyp size, high grade of intraepithelial neoplasia, villous and tubulovillous adenoma, and histological epithelial localization.
  • [MeSH-major] Adenoma / enzymology. Adenoma / pathology. Arachidonate 5-Lipoxygenase / metabolism. Colonic Neoplasms / enzymology. Colonic Neoplasms / pathology. Precancerous Conditions / enzymology. Precancerous Conditions / pathology

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  • [Cites] Gastroenterology. 2003 Jan;124(1):57-70 [12512030.001]
  • [Cites] Int J Mol Med. 2004 Mar;13(3):389-93 [14767568.001]
  • [Cites] Clin Cancer Res. 2004 Oct 1;10(19):6703-9 [15475461.001]
  • [Cites] Korean J Gastroenterol. 2004 Oct;44(4):206-11 [15505432.001]
  • [Cites] Anticancer Res. 1998 Mar-Apr;18(2A):791-800 [9615721.001]
  • [Cites] Carcinogenesis. 1998 Aug;19(8):1393-400 [9744535.001]
  • [Cites] Prostate. 1998 Nov 1;37(3):161-73 [9792133.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13182-7 [9789062.001]
  • [Cites] Int J Cancer. 1999 Nov 12;83(4):470-5 [10508481.001]
  • [Cites] J Exp Clin Cancer Res. 2005 Jun;24(2):279-87 [16110762.001]
  • [Cites] Anticancer Res. 2005 May-Jun;25(3B):2065-8 [16158946.001]
  • [Cites] Gut. 2006 Jan;55(1):54-61 [16085694.001]
  • [Cites] World J Gastroenterol. 2006 Oct 21;12(39):6355-60 [17072961.001]
  • [Cites] Clin Cancer Res. 2008 Oct 15;14(20):6525-30 [18927292.001]
  • [Cites] Am J Pathol. 2000 Feb;156(2):545-53 [10666384.001]
  • [Cites] Aliment Pharmacol Ther. 2000 Apr;14 Suppl 1:64-7 [10807405.001]
  • [Cites] Cancer. 2000 Dec 15;89(12):2637-45 [11135226.001]
  • [Cites] J Gastroenterol Hepatol. 2000 Nov;15(11):1277-81 [11129221.001]
  • [Cites] J Pathol. 2002 Dec;198(4):428-34 [12434411.001]
  • [Cites] Am J Pathol. 2002 Aug;161(2):421-8 [12163367.001]
  • [Cites] Cancer. 2001 Feb 15;91(4):737-43 [11241241.001]
  • [Cites] Pathol Int. 2002 Apr;52(4):272-6 [12031082.001]
  • [Cites] Oncogene. 2001 Feb 15;20(7):819-27 [11314016.001]
  • (PMID = 20549218.001).
  • [ISSN] 1432-1262
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 1.13.11.34 / Arachidonate 5-Lipoxygenase
  • [Other-IDs] NLM/ PMC2912725
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48. Einspahr JG, Martinez ME, Jiang R, Hsu CH, Rashid A, Bhattacharrya AK, Ahnen DJ, Jacobs ET, Houlihan PS, Webb CR, Alberts DS, Hamilton SR: Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics. Cancer Epidemiol Biomarkers Prev; 2006 Aug;15(8):1443-50
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  • [Title] Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics.
  • In colorectal tumorigenesis, Ki-ras proto-oncogene mutation often occurs early in the adenoma-adenocarcinoma sequence, whereas mutation of the p53 gene is associated with late progression to carcinoma.
  • We evaluated the relationship of demographic and clinicopathologic characteristics to Ki-ras mutation and p53 gene product overexpression in 1,093 baseline sporadic colorectal adenomas from 926 individuals enrolled in a phase III recurrence prevention trial.
  • Multivariate analysis found older age, rectal location, and villous histology to be independently associated with Ki-ras mutation.
  • Individuals with an advanced adenoma (>or=1 cm or high-grade dysplasia or villous histology) had a 4-fold higher likelihood of Ki-ras mutation [odds ratios (OR), 3.96; 95% confidence intervals (CI), 2.54-6.18].
  • Ki-ras mutations in codon 12 and of the G-to-A transition type were more frequent in older individuals, whereas G-to-T transversion was more frequent in rectal adenomas than in the colon.
  • Large adenoma size (>or=1 cm), high-grade dysplasia, and villous histology were independently associated with p53 overexpression, with the strongest association for advanced adenomas (OR, 7.20; 95% CI, 3.01-17.22).
  • Individuals with a Ki-ras mutated adenoma were more likely to overexpress p53 (OR, 2.46; 95% CI, 1.36-4.46), and 94.8% of adenomas with both alterations were classified as advanced (P <or= 0.0001).
  • Our large cross-sectional study supports the role of both Ki-ras and p53 in the progression of adenomas and shows that their molecular pathogenesis differs by anatomic location, age, and mucosal predisposition as evidenced by previous history of a polyp.

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  • [Cites] Int J Cancer. 2002 Feb 20;97(6):823-7 [11857362.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9433-8 [12093899.001]
  • [Cites] Annu Rev Genomics Hum Genet. 2002;3:101-28 [12142355.001]
  • [Cites] Carcinogenesis. 2003 Apr;24(4):703-10 [12727799.001]
  • [Cites] CA Cancer J Clin. 2004 Jan-Feb;54(1):8-29 [14974761.001]
  • [Cites] Proc R Soc Med. 1974 Jun;67(6 Pt 1):451-7 [4853754.001]
  • [Cites] Nature. 1987 May 28-Jun 3;327(6120):293-7 [3587348.001]
  • [Cites] Mutat Res. 1988 May;195(3):255-71 [3283542.001]
  • [Cites] N Engl J Med. 1988 Sep 1;319(9):525-32 [2841597.001]
  • [Cites] J Pathol. 1989 Mar;157(3):193-9 [2926561.001]
  • [Cites] Cell. 1990 Jun 1;61(5):759-67 [2188735.001]
  • [Cites] Proc Natl Acad Sci U S A. 1990 Oct;87(19):7555-9 [1699228.001]
  • [Cites] Am J Pathol. 1991 Apr;138(4):807-13 [1707233.001]
  • [Cites] Cancer Res. 1991 Aug 15;51(16):4436-42 [1868464.001]
  • [Cites] FASEB J. 1992 Mar;6(6):2302-10 [1544541.001]
  • [Cites] Int J Cancer. 1992 Mar 12;50(5):683-8 [1347513.001]
  • [Cites] Am J Clin Pathol. 1992 Feb;97(2):244-9 [1546693.001]
  • [Cites] Cancer Res. 1992 Apr 1;52(7):1974-80 [1551126.001]
  • [Cites] Science. 1992 Jan 10;255(5041):159 [1553541.001]
  • [Cites] Cancer Res. 1992 Jul 15;52(14):3965-71 [1319835.001]
  • [Cites] FASEB J. 1992 Jul;6(10):2783-90 [1321771.001]
  • [Cites] Gastroenterology. 1993 Jan;104(1):57-64 [8419262.001]
  • [Cites] Am J Pathol. 1993 Jan;142(1):87-93 [7678722.001]
  • [Cites] Gut. 1993 Mar;34(3):392-6 [8472989.001]
  • [Cites] Science. 1993 May 7;260(5109):816-9 [8484122.001]
  • [Cites] Int J Cancer. 1993 May 8;54(2):249-54 [8486427.001]
  • [Cites] Gut. 1993 May;34(5):621-4 [8504962.001]
  • [Cites] Anticancer Res. 1993 May-Jun;13(3):667-70 [8317895.001]
  • [Cites] Cell. 1993 Dec 17;75(6):1215-25 [8261515.001]
  • [Cites] Br J Cancer. 1994 Feb;69(2):367-71 [8297737.001]
  • [Cites] Jpn J Cancer Res. 1994 Feb;85(2):147-51 [8144396.001]
  • [Cites] Oncology. 1994 May-Jun;51(3):224-7 [7910956.001]
  • [Cites] Cancer Res. 1994 Sep 1;54(17):4798-804 [8062281.001]
  • [Cites] Cancer Detect Prev. 1994;18(3):187-95 [8076381.001]
  • [Cites] J Pathol. 1994 Jan;172(1):5-12 [7931827.001]
  • [Cites] Cancer. 1995 Feb 15;75(4):953-7 [7842415.001]
  • [Cites] Int J Cancer. 1995 Feb 20;64(1):47-51 [7665248.001]
  • [Cites] Diagn Mol Pathol. 1995 Sep;4(3):198-202 [7493139.001]
  • [Cites] Biotech Histochem. 1995 Mar;70(2):90-4 [7578594.001]
  • [Cites] Am J Surg. 1996 Jan;171(1):41-6 [8554149.001]
  • [Cites] Br J Cancer. 1996 Jul;74(1):99-108 [8679466.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1996 Apr;5(4):285-91 [8722220.001]
  • [Cites] Hum Pathol. 1996 Oct;27(10):1042-9 [8892588.001]
  • [Cites] J Pathol. 1996 Dec;180(4):357-63 [9014854.001]
  • [Cites] Br J Cancer. 1997;75(3):341-7 [9020477.001]
  • [Cites] Cell. 1997 Feb 7;88(3):323-31 [9039259.001]
  • [Cites] Anticancer Res. 1996 Nov-Dec;16(6B):3839-44 [9042267.001]
  • [Cites] J Pathol. 1997 Mar;181(3):281-6 [9155713.001]
  • [Cites] Cancer Res. 1997 Jun 15;57(12):2485-92 [9192830.001]
  • [Cites] Dis Colon Rectum. 1997 Oct;40(10 Suppl):S16-22 [9378006.001]
  • [Cites] Scand J Gastroenterol. 1997 Oct;32(10):1035-41 [9361177.001]
  • [Cites] Cancer Res. 1998 Mar 15;58(6):1149-58 [9515799.001]
  • [Cites] J Natl Cancer Inst. 1998 May 6;90(9):675-84 [9586664.001]
  • [Cites] Am J Gastroenterol. 1998 Jun;93(6):980-4 [9647033.001]
  • [Cites] Anticancer Res. 1998 May-Jun;18(3A):1677-82 [9673389.001]
  • [Cites] Eur J Cancer. 1998 Mar;34(4):518-21 [9713302.001]
  • [Cites] Gut. 1999 Jun;44(6):826-33 [10323885.001]
  • [Cites] Clin Chem Lab Med. 1999 Jul;37(7):723-7 [10510729.001]
  • [Cites] J Natl Cancer Inst. 2005 Sep 21;97(18):1330-8 [16174854.001]
  • [Cites] Jpn J Cancer Res. 1991 Mar;82(3):245-9 [1708754.001]
  • [Cites] Cancer Res. 1999 Oct 15;59(20):5181-5 [10537295.001]
  • [Cites] Carcinogenesis. 2000 Mar;21(3):387-95 [10688859.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2225-8 [10681434.001]
  • [Cites] N Engl J Med. 2000 Apr 20;342(16):1156-62 [10770980.001]
  • [Cites] Eur J Cancer Prev. 2000 Feb;9(1):41-7 [10777009.001]
  • [Cites] Dig Dis. 1999;17(4):225-9 [10754362.001]
  • [Cites] Gastroenterology. 2000 Jun;118(6):1045-50 [10833479.001]
  • [Cites] Eur J Cancer. 2000 May;36(8):1008-15 [10885605.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2000 Nov;9(11):1193-7 [11097226.001]
  • [Cites] Physiol Rev. 2001 Jul;81(3):1031-64 [11427691.001]
  • [Cites] Gastroenterology. 2001 Aug;121(2):302-9 [11487539.001]
  • [Cites] Gastroenterology. 2001 Sep;121(3):599-611 [11522744.001]
  • [Cites] Br J Cancer. 2001 Sep 1;85(5):692-6 [11531254.001]
  • [Cites] Mutat Res. 2001 Nov 1;483(1-2):73-81 [11600135.001]
  • [Cites] Cancer. 2002 Jan 1;94(1):219-27 [11815980.001]
  • [ErratumIn] Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):2016. Rashid, Asif [added]
  • (PMID = 16896030.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA023074; United States / NCI NIH HHS / CA / P30 CA016672; United States / NCI NIH HHS / CA / CA16672; United States / NCI NIH HHS / CA / P01 CA041108; United States / NCI NIH HHS / CA / CA23074; United States / NCI NIH HHS / CA / CA41108
  • [Publication-type] Clinical Trial, Phase III; Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS430412; NLM/ PMC3547362
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49. Ozsunar Y, Coskun G, Delibaş N, Uz B, Yükselen V: Diagnostic accuracy and tolerability of contrast enhanced CT colonoscopy in symptomatic patients with increased risk for colorectal cancer. Eur J Radiol; 2009 Sep;71(3):513-8
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  • Two masses and eight polyps, consisted of 1 tubulovillous, 1 tubular, 2 villous adenoma, 4 adenomatous polyp, 4 adenocarcinoma, were identified.

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  • (PMID = 18597964.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media
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50. Zorzi M, Barca A, Falcini F, Grazzini G, Pizzuti R, Ravaioli A, Sassoli de Bianchi P, Senore C, Sigillito A, Vettorazzi M, Visioli C: Screening for colorectal cancer in Italy: 2005 survey. Epidemiol Prev; 2007 Mar-Jun;31(2-3 Suppl 2):49-60
International Agency for Research on Cancer - Screening Group. diagnostics - Planning and Implementing Cervical Cancer Prevention and Control Programs: A Manual for Managers .

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  • During 2005, 52 programmes, adopting faecal occult blood testing (FOBT), sigmoidoscopy (FS), or a combination of both, were active in Italy.
  • At first screening, the detection rate (DR) per 1000 screened subjects was 3.7 and 16.8 for invasive cancer and advanced adenomas (AA) (adenomas with a diameter > or =1 cm, with villous/tubulo-villous type or with high-grade dysplasia) respectively; the corresponding figures at repeat screening were 1.1 for cancer and 4.9 for AA.
  • The DR of cancer and adenomas increased with age and it was higher among males, 55% of screen-detected cancers were at TNM stage I.
  • [MeSH-major] Adenocarcinoma / epidemiology. Adenoma / epidemiology. Colorectal Neoplasms / epidemiology. Mass Screening / statistics & numerical data. National Health Programs / statistics & numerical data. Occult Blood. Sigmoidoscopy / statistics & numerical data

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  • (PMID = 17824362.001).
  • [ISSN] 1120-9763
  • [Journal-full-title] Epidemiologia e prevenzione
  • [ISO-abbreviation] Epidemiol Prev
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Italy
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51. Jones M, Helliwell P, Pritchard C, Tharakan J, Mathew J: Helicobacter pylori in colorectal neoplasms: is there an aetiological relationship? World J Surg Oncol; 2007;5:51
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  • METHODS: Paraffin processed colonic tissue blocks of normal colonic mucosa (n = 60), and patients diagnosed as adenoma (n = 60), and adenocarcinoma (n = 60) were retrieved from our archive; the adenoma group included tubular (n = 20), tubulovillous (n = 20) and villous adenomas (n = 20).
  • RESULTS: Significant numbers of Helicobacter pylori were identified in tubular adenomas (OR = 11.13; 95%CI = 1.62-76.70), tubulovillous adenomas (OR = 10.45; 95%CI = 1.52-71.52) and adenocarcinomas (OR = 8.13; 95%CI = 1.40-46.99) compared to controls: there was no association in numbers of Helicobacter pylori and villous adenomas (OR = 2.95; 95%CI = 0.29-9.96).
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / microbiology. Adenoma / epidemiology. Adenoma / microbiology. Adult. Aged. Aged, 80 and over. Biopsy, Needle. Female. Humans. Incidence. Intestinal Mucosa / microbiology. Intestinal Mucosa / pathology. Male. Middle Aged. Odds Ratio. Pilot Projects. Reference Values. Risk Assessment. Sampling Studies. Sensitivity and Specificity

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  • [Cites] J Clin Pathol. 1989 Feb;42(2):132-4 [2921353.001]
  • [Cites] N Engl J Med. 1988 Sep 1;319(9):525-32 [2841597.001]
  • [Cites] Lancet. 1992 Nov 14;340(8829):1194-5 [1359263.001]
  • [Cites] Lancet. 1993 May 22;341(8856):1348 [8098476.001]
  • [Cites] Am J Clin Pathol. 1994 Oct;102(4):503-7 [7524304.001]
  • [Cites] J Natl Cancer Inst. 1995 May 17;87(10):762-3 [7563155.001]
  • [Cites] J Clin Pathol. 1996 Feb;49(2):107-11 [8655673.001]
  • [Cites] Ital J Gastroenterol. 1996 Oct-Nov;28(8):447-51 [9032587.001]
  • [Cites] Curr Probl Cancer. 1997 Sep-Oct;21(5):233-300 [9438104.001]
  • [Cites] J Clin Gastroenterol. 1997 Dec;25(4):605-7 [9451672.001]
  • [Cites] Am J Gastroenterol. 1998 Feb;93(2):223-6 [9468247.001]
  • [Cites] Helicobacter. 1998 Jun;3(2):103-9 [9631308.001]
  • [Cites] Helicobacter. 1998 Jun;3(2):143 [9631317.001]
  • [Cites] J Clin Pathol. 1998 Jul;51(7):506-11 [9797726.001]
  • [Cites] Lancet. 1999 Jan 30;353(9150):391-9 [9950460.001]
  • [Cites] Am J Gastroenterol. 1999 Apr;94(4):1121-2 [10201512.001]
  • [Cites] Eur J Gastroenterol Hepatol. 1999 Mar;11(3):251-6 [10333197.001]
  • [Cites] Digestion. 1999;60(3):210-5 [10343134.001]
  • [Cites] Gut. 1999 Jul;45 Suppl 1:I13-7 [10457030.001]
  • [Cites] J Med Microbiol. 2005 Nov;54(Pt 11):1031-5 [16192433.001]
  • [Cites] J Gastroenterol. 2005 Sep;40(9):887-93 [16211345.001]
  • [Cites] Int J Cancer. 2005 Dec 20;117(6):1058-9 [15986436.001]
  • [Cites] Cancer Res. 2006 Jan 15;66(2):828-38 [16424015.001]
  • [Cites] Cancer Res. 2006 Aug 1;66(15):7395-400 [16885333.001]
  • [Cites] PLoS Pathog. 2006 Sep;2(9):e97 [17002496.001]
  • [Cites] J Clin Pathol. 1999 May;52(5):338-44 [10560352.001]
  • [Cites] J Physiol Pharmacol. 1999 Dec;50(5):683-94 [10695551.001]
  • [Cites] Isr Med Assoc J. 2000 Jan;2(1):6-9 [10892362.001]
  • [Cites] BMJ. 2000 Oct 7;321(7265):886-9 [11021873.001]
  • [Cites] Regul Pept. 2000 Sep 25;93(1-3):13-9 [11033048.001]
  • [Cites] Semin Gastrointest Dis. 2000 Oct;11(4):229-37 [11057950.001]
  • [Cites] J Clin Pathol. 2000 Oct;53(10):756-9 [11064668.001]
  • [Cites] Am J Gastroenterol. 2001 Jan;96(1):84-8 [11197293.001]
  • [Cites] Int J Colorectal Dis. 2001 Aug;16(4):202-10 [11515678.001]
  • [Cites] Br J Biomed Sci. 2001;58(3):190-6 [11575743.001]
  • [Cites] Gut. 2001 Nov;49(5):601-6 [11600455.001]
  • [Cites] Med Sci Monit. 2001 Nov-Dec;7(6):1171-81 [11687726.001]
  • [Cites] Am J Gastroenterol. 2001 Dec;96(12):3406-10 [11774957.001]
  • [Cites] Gut. 2002 Feb;50(2):273-83 [11788573.001]
  • [Cites] Helicobacter. 2002 Apr;7(2):112-5 [11966871.001]
  • [Cites] Dig Dis Sci. 2002 Sep;47(9):1984-91 [12353842.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2002 Oct;11(10 Pt 1):1095-9 [12376513.001]
  • [Cites] J Gastroenterol Hepatol. 2002 Nov;17(11):1161-4 [12453274.001]
  • [Cites] Pathol Res Pract. 2002;198(11):731-4 [12530575.001]
  • [Cites] Am J Pathol. 2003 Feb;162(2):691-702 [12547727.001]
  • [Cites] Aliment Pharmacol Ther. 2003 Sep 1;18(5):481-6 [12950420.001]
  • [Cites] Helicobacter. 2004 Apr;9(2):115-23 [15068412.001]
  • [Cites] Appl Environ Microbiol. 1983 Mar;45(3):1025-33 [6847178.001]
  • [Cites] Am J Clin Pathol. 1990 Jan;93(1):144-7 [2294694.001]
  • (PMID = 17498313.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Bacterial
  • [Other-IDs] NLM/ PMC1885433
  • [General-notes] NLM/ Original DateCompleted: 20070807
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52. Anderson JC, Alpern Z, Sethi G, Messina CR, Martin C, Hubbard PM, Grimson R, Ells PF, Shaw RD: Prevalence and risk of colorectal neoplasia in consumers of alcohol in a screening population. Am J Gastroenterol; 2005 Sep;100(9):2049-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Our outcome was the endoscopic detection of significant colorectal neoplasia, which included adenocarcinoma, high-grade dysplasia, villous tissue, adenomas 1 cm or greater and multiple (>2) adenomas of any size.
  • [MeSH-major] Alcohol Drinking / adverse effects. Colonoscopy. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / etiology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / etiology. Adenoma / diagnosis. Adenoma / etiology. Female. Humans. Male. Middle Aged. Precancerous Conditions / diagnosis. Precancerous Conditions / etiology. Prevalence

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  • (PMID = 16128951.001).
  • [ISSN] 0002-9270
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Okamoto M, Kawabe T, Yamaji Y, Kato J, Ikenoue T, Togo G, Yoshida H, Shiratori Y, Omata M: Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy. World J Gastroenterol; 2005 Apr 21;11(15):2249-54
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  • METHODS: We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination).
  • Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma).
  • RESULTS: The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings.
  • Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer.
  • [MeSH-major] Adenoma / epidemiology. Adenoma / pathology. Colonic Neoplasms / epidemiology. Colonic Neoplasms / pathology. Colonoscopy

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  • (PMID = 15818734.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4305807
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54. Zhou ZY, Han Y, Wang LP: [A study on microsatellite instability status for colorectal serrated lesions]. Zhonghua Nei Ke Za Zhi; 2009 May;48(5):402-5
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  • OBJECTIVE: To verify the traditional serrated pathway by comparing microsatellite instability (MSI) status among traditional serrated adenoma, traditional adenoma, serrated colorectal cancer and non-serrated colorectal cancer.
  • METHODS: Seventy-five paraffin-embedded tissue samples, including 15 with serrated adenocarcinoma (Sca), 20 with non-serrated adenocarcinoma (N-Sca), 20 with traditional serrated adenoma (TSA) and 20 with villous adenoma (AD) were collected from the pathology department of our hospital.
  • RESULTS: Six of 18 samples with TSA harbored MSI-H and twelve MSI-L/MSS; 18 samples with conventional adenoma were exclusively of MSS; 3 of 13 samples of serrated carcinoma harbored MSI-H and ten MSI-L/MSS; 18 of 19 N-Sca samples harbored MSI-L/MSS and only one MSI-H.
  • With Chi-square test, the MSI frequency in AD group and N-Sca group was significantly lower than that in TSA group and Sca group (P<0.05); but with no statistical difference between the TSA group and Sca groups (P>0.05).
  • CONCLUSION: MSI-H frequency in AD group and N-Sca group was obviously lower than that of TSA group and Sca group.
  • It is concluded that there might be a new traditional serrated neoplasia pathway which is different from the conventional adenoma-carcinoma carcinogenesis pathway, but we still need prospective follow-up studies to verify its existence.
  • [MeSH-major] Adenoma, Villous / genetics. Colorectal Neoplasms / genetics. Microsatellite Instability

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  • (PMID = 19615160.001).
  • [ISSN] 0578-1426
  • [Journal-full-title] Zhonghua nei ke za zhi
  • [ISO-abbreviation] Zhonghua Nei Ke Za Zhi
  • [Language] chi
  • [Publication-type] Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] China
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55. Berhane C, Denning D: Incidental finding of colorectal cancer in screening colonoscopy and its cost effectiveness. Am Surg; 2009 Aug;75(8):699-703; discussion 703-4
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  • The objective of this study is to measure the risk of colorectal cancer and adenoma with screening colonoscopy and its cost effectiveness.
  • Among those 11,808 screening colonoscopies performed, advance neoplasm (adenocarcinoma) was detected in 272 (2.3%) patients; age 50 to 90, with mean age of 64-years-old.
  • Fourteen per cent had hyperplastic polyps, 15 per cent had tubular adenoma, and 8.6 per cent villous adenoma.
  • Adenoma with high grade dysplasia was found in 6.6 per cent, and 5.5 per cent had nonadenomatous lesions.
  • Rate of adenocarcinoma from 2000 to 2006 was (24/470, 29/520, 33/891, 37/961, 46/2889, 49/2977, and 54/3100).
  • [MeSH-major] Adenoma / diagnosis. Colonic Polyps / diagnosis. Colonoscopy / economics. Colorectal Neoplasms / diagnosis. Incidental Findings


56. Goldstein PJ, Cabanas J, da Silva RG, Sugarbaker PH: Pseudomyxoma peritonei arising from colonic polyps. Eur J Surg Oncol; 2006 Sep;32(7):764-6
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  • AIMS: Pseudomyxoma peritonei may have as its primary site a mucinous gastrointestinal adenoma or carcinoma that gains access to the peritoneal cavity.
  • [MeSH-minor] Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / surgery. Adenoma, Villous / pathology. Adenoma, Villous / surgery. Adult. Aged. Female. Humans

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  • (PMID = 16765563.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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57. Kim YS, Kim N, Kim SH, Park MJ, Lim SH, Yim JY, Cho KR, Kim SS, Kim DH, Eun HW, Cho KS, Kim JH, Choi BI, Jung HC, Song IS, Shin CS, Cho SH, Oh BH: The efficacy of intravenous contrast-enhanced 16-raw multidetector CT colonography for detecting patients with colorectal polyps in an asymptomatic population in Korea. J Clin Gastroenterol; 2008 Aug;42(7):791-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenocarcinoma / physiopathology. Adenocarcinoma / radiography. Adenoma, Villous / physiopathology. Adenoma, Villous / radiography. Colonic Neoplasms / physiopathology. Colonic Neoplasms / radiography. Colonoscopy / methods. Contrast Media. Female. Humans. Korea. Male. Middle Aged. Sensitivity and Specificity

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  • (PMID = 18580500.001).
  • [ISSN] 1539-2031
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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58. Ayhan S, Isisag A, Saruc M, Nese N, Demir MA, Kucukmetin NT: The role of pRB, p16 and cyclin D1 in colonic carcinogenesis. Hepatogastroenterology; 2010 Mar-Apr;57(98):251-6
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  • BACKGROUND/AIMS: This study is aimed to investigate abnormal expression of the Rb protein (pRb), p16(INK4a) (p16) and cyclin D1 in colorectal adenomas and adenocarcinomas and to assess the possible alterations in Rb pathway in colorectal carcinogenesis.
  • METHODOLOGY: 44 cases of colorectal adenoma and 44 cases of colorectal adenocarcinoma were examined histopathologically and immunohistochemically using monoclonal antibodies to identify abnormalities of pRb, p16, and cyclin D1 expression.
  • RESULTS: In 70.5% of the adenomas and 97.7% of the adenocarcinomas, an overexpression of pRb was found.
  • There was a statistically significant relationship between the immunoreactivity of pRb and villous/tubulovillous types of adenomas (p < 0.05).
  • There was a loss of p16 expression in 84.1% of adenomas and 61.4% of adenocarcinomas.
  • Statistically significantly, the p16 overexpression was not seen in any of tubular adenomas (p < 0.001).
  • Overexpression of cyclin D1 was found in only 9.1% of adenomas, while 31.8% of adenocarcinomas overexpressed this protein.
  • Loss of expression of cyclin D1 was similar in adenomas and adenocarcinomas (27.3% and 25%, respectively).
  • Staining degrees of all three cell cycle proteins were shown to be statistically different in adenomas and adenocarcinomas, for pRb (p = 0.001), for p16 ( p = 0.045), and cyclin D1 ( p = 0.05).
  • Also, there was only a mild agreement with respect to p16 and cyclin D1 relationship between for adenomas ( K = +0.28 p = 0.051) and for adenocarcinomas ( K = +0.35 p = 0.017).
  • CONCLUSIONS: pRb, p16 and cyclin D1 are shown to be aberrantly expressed in both colorectal adenomas and adenocarcinomas.
  • It can be claimed that disturbances in Rb pathway take part in colonic carcinogenesis and pRb, p16 and cyclin D1 play an ever increasing role in the further stages of adenoma-carcinoma sequence.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma / metabolism. Colorectal Neoplasms / metabolism. Cyclin D1 / metabolism. Cyclin-Dependent Kinase Inhibitor p16 / metabolism. Retinoblastoma Protein / metabolism

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  • (PMID = 20583423.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cell Cycle Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Retinoblastoma Protein; 136601-57-5 / Cyclin D1
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59. Ibrahim OO, Anjorin AS, Afolayan AE, Badmos KB: Pathological characterization of colorectal polyps in Ilorin, Nigeria. Afr J Med Med Sci; 2010 Sep;39(3):215-9
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  • Colorectal polyps especially the adenomas are recognized precursors of colorectal carcinoma.
  • This is a retrospective review of all cases ofcolorectal polyps that were received, processed and had histological diagnosis in our centre between 1979 and 2008 using the request cards and hematoxylin and eosin stained slides.
  • Seventeen (38.6%) were adenomas, 9 (20.5%) were juvenile polyps, 8 (18.2%) were inflammatory polyps, 4 cases were lipomatous polyps, 3 were leiomatous polyps, and one each of lymphoid polyp, hamartomatous polyp and neurofibromatous polyp.
  • Of the adenomas, 11 (58.8%) were tubular, 5 (29.4%) were villous, 1 (5.9%) was tubulovillous, and one was a villous adenoma with a focus of malignant transformation.
  • [MeSH-major] Adenocarcinoma / pathology. Colonic Polyps / pathology. Colorectal Neoplasms / pathology

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  • (PMID = 21416791.001).
  • [ISSN] 0309-3913
  • [Journal-full-title] African journal of medicine and medical sciences
  • [ISO-abbreviation] Afr J Med Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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60. Anderson JC, Latreille M, Messina C, Alpern Z, Grimson R, Martin C, Hubbard P, Shaw RD: Smokers as a high-risk group: data from a screening population. J Clin Gastroenterol; 2009 Sep;43(8):747-52
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  • Our outcome was endoscopically detected significant colorectal neoplasia that included large (>1 cm) tubular adenomas, villous adenomas, multiple (3 or more) adenomas, high-grade dysplasia, and adenocarcinoma.
  • [MeSH-major] Adenocarcinoma. Adenoma. Colorectal Neoplasms. Smoking / adverse effects

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  • (PMID = 19407663.001).
  • [ISSN] 1539-2031
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Onaitis M, Ludwig K, Perez-Tamayo A, Gottfried M, Russell L, Shadduck P, Pappas T, Seigler HF, Tyler DS: The Kraske procedure: a critical analysis of a surgical approach for mid-rectal lesions. J Surg Oncol; 2006 Sep 1;94(3):194-202
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  • RESULTS: Of the 22 patients, 13 underwent resection of an adenocarcinoma and 9 underwent resection of a villous adenoma.
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Digestive System Surgical Procedures / methods. Rectal Neoplasms / surgery. Rectum / surgery

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  • [Copyright] 2006 Wiley-Liss, Inc.
  • (PMID = 16900535.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Augoff K, Rabczynski J, Tabola R, Czapla L, Ratajczak K, Grabowski K: Immunohistochemical study of decorin expression in polyps and carcinomas of the colon. Med Sci Monit; 2008 Oct;14(10):CR530-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It was hypothesized that physiological expression of decorin may be associated with cellular senescence of the colorectal mucosa and that its down-regulation, promoting an increase in cellular proliferation, could participate in the progression of adenoma to adenocarcinoma.
  • MATERIAL/METHODS: Tissue samples were obtained from 41 patients with different types of colonic polyps (6 hyperplastic adenomas, 34 neoplastic adenomas, and 1 adenomatous polyp with focal carcinoma) and 12 patients with colon cancer.
  • RESULTS: Normal and hyperplastic tissues and the majority of tubular adenomas showed strong expression of decorin in the stroma.
  • Adenomas with a villous component showed moderate and very low decorin immunoreactivity.
  • The decrease in decorin reactivity in tubulo-villous adenomas was significant as compared with other polyps and controls.
  • Weak decorin immunoreactivity in stroma adjacent to clusters of cancerous cells was also found in most cases of common types of adenocarcinoma, but not in adenocarcinoma mucinosum.

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  • (PMID = 18830193.001).
  • [ISSN] 1643-3750
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / DCN protein, human; 0 / Decorin; 0 / Extracellular Matrix Proteins; 0 / Proteoglycans
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63. Thomas AA, Rackley RR, Lee U, Goldman HB, Vasavada SP, Hansel DE: Urethral diverticula in 90 female patients: a study with emphasis on neoplastic alterations. J Urol; 2008 Dec;180(6):2463-7
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  • Neoplastic alterations identified in 5 patients (6%) were glandular in nature, including 1 clear cell and 4 invasive adenocarcinomas.
  • Superficial changes associated with invasive carcinoma included villous adenoma in 1 case, intestinal metaplasia in 2 and high grade dysplasia in 3.
  • Of the 90 patients the remaining 82 demonstrated benign findings, including nephrogenic adenoma in 10 (11%).
  • In 2 patients with invasive adenocarcinoma metastatic disease subsequently developed, of which they died.
  • CONCLUSIONS: Although most cases of surgically resected diverticula demonstrate benign features, approximately 10% show atypical glandular findings, including invasive adenocarcinoma.
  • [MeSH-major] Diverticulum / complications. Diverticulum / pathology. Urethral Diseases / complications. Urethral Diseases / pathology. Urethral Neoplasms / diagnosis. Urethral Neoplasms / pathology

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  • (PMID = 18930487.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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64. Spalding DR, Isla AM, Thompson JN, Williamson RC: Pancreas-sparing distal duodenectomy for infrapapillary neoplasms. Ann R Coll Surg Engl; 2007 Mar;89(2):130-5
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  • There were 11 malignant neoplasms (adenocarcinoma 5, stromal tumour 4, recurrent seminoma 1, plasmacytoma 1), 2 benign neoplasms (villous adenoma, lipoma) and 1 patient with steroid-induced ulceration.
  • [MeSH-major] Adenocarcinoma, Papillary / surgery. Duodenal Neoplasms / surgery. Pancreas / surgery. Pancreaticoduodenectomy / methods

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  • [Cites] Dis Colon Rectum. 1999 Dec;42(12):1533-6 [10613470.001]
  • [Cites] Hepatogastroenterology. 1999 May-Jun;46(27):1953-8 [10430376.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 1999;6(4):414-7 [10664293.001]
  • [Cites] Dig Surg. 2000;17(4):410-2 [11053954.001]
  • [Cites] Ned Tijdschr Geneeskd. 2002 Mar 30;146(13):621-4 [11957383.001]
  • [Cites] Arch Surg. 2002 May;137(5):557-62; discussion 562-3 [11982469.001]
  • [Cites] J Gastrointest Surg. 2002 Jan-Feb;6(1):82-7 [11986022.001]
  • [Cites] Eur J Surg. 2002;168(2):74-7 [12113274.001]
  • [Cites] Surg Endosc. 2002 Sep;16(9):1362-3 [12072993.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 2002;9(3):393-6 [12353155.001]
  • [Cites] Hepatogastroenterology. 2003 May-Jun;50(51):711-3 [12828067.001]
  • [Cites] Hepatogastroenterology. 2004 May-Jun;51(57):727-31 [15143902.001]
  • [Cites] Surg Gynecol Obstet. 1976 Jun;142(6):858-60 [936029.001]
  • [Cites] Am J Proctol Gastroenterol Colon Rectal Surg. 1981 Aug;32(8):18-21, 28 [7027808.001]
  • [Cites] Ann Surg. 1983 Feb;197(2):172-8 [6337568.001]
  • [Cites] Cancer. 1985 Nov 1;56(9):2242-50 [4052969.001]
  • [Cites] World J Surg. 1985 Dec;9(6):914-20 [4082613.001]
  • [Cites] Ann Surg. 1986 Mar;203(3):301-6 [3954483.001]
  • [Cites] Am J Surg. 1987 Apr;153(4):350-4 [3565678.001]
  • [Cites] Br J Surg. 1988 Feb;75(2):184-6 [3349313.001]
  • [Cites] Ann Surg. 1989 May;209(5):593-8; discussion 598-9 [2650645.001]
  • [Cites] Ann Surg. 1989 Oct;210(4):544-54; discussion 554-6 [2679459.001]
  • [Cites] Arch Surg. 1990 Aug;125(8):961-5 [2378560.001]
  • [Cites] Arch Surg. 1992 Aug;127(8):945-9; discussion 949-50 [1353671.001]
  • [Cites] Ann Surg. 1993 May;217(5):430-5; discussion 435-8 [8098202.001]
  • [Cites] Br J Surg. 1994 Oct;81(10):1472-4 [7820475.001]
  • [Cites] J Surg Oncol. 1995 Jan;58(1):70-3 [7823577.001]
  • [Cites] Surgery. 1995 Mar;117(3):254-9 [7878529.001]
  • [Cites] Ann R Coll Surg Engl. 1994 Nov;76(6):403-4 [7702324.001]
  • [Cites] Jpn J Clin Oncol. 1995 Jun;25(3):109-12 [7596048.001]
  • [Cites] Ann Surg. 1995 Oct;222(4):580-8; discussion 588-92 [7574936.001]
  • [Cites] Am J Surg. 1996 Jan;171(1):62-7 [8554153.001]
  • [Cites] Hepatogastroenterology. 1996 Jul-Aug;43(10):835-8 [8884299.001]
  • [Cites] Gastroenterology. 1997 Sep;113(3):983-94 [9287993.001]
  • [Cites] Ann Surg. 1997 Sep;226(3):248-57; discussion 257-60 [9339931.001]
  • [Cites] J Gastrointest Surg. 1998 Jan-Feb;2(1):79-87 [9841972.001]
  • [Cites] Dig Surg. 1998;15(5):398-403 [9845621.001]
  • [Cites] Dig Surg. 1999;16(1):22-5 [9949263.001]
  • [Cites] J Gastrointest Surg. 2000 Jan-Feb;4(1):13-21, discussion 22-3 [10631358.001]
  • (PMID = 17346405.001).
  • [ISSN] 1478-7083
  • [Journal-full-title] Annals of the Royal College of Surgeons of England
  • [ISO-abbreviation] Ann R Coll Surg Engl
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1964558
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65. Zuo ZG, Song HY, Li J, Xu C, Zhou ZH, Ni SC, Chen SQ: [Clinical application of intersphincteric resection in the anal-preserving operation for ultra-low rectal carcinoma]. Zhonghua Zhong Liu Za Zhi; 2009 Dec;31(12):941-4

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  • The pathological types were as follows: 28 cases of adenocarcinoma (11 were well differentiated, 17 moderately differentiated), 1 case of papillary carcinoma and 5 cases of villous adenoma with malignant change.
  • [MeSH-major] Adenocarcinoma / surgery. Anal Canal / surgery. Rectal Neoplasms / surgery. Rectum / surgery
  • [MeSH-minor] Adenoma, Villous / pathology. Adenoma, Villous / surgery. Adult. Aged. Aged, 80 and over. Anastomosis, Surgical. Carcinoma, Papillary / pathology. Carcinoma, Papillary / surgery. Female. Follow-Up Studies. Humans. Liver Neoplasms / secondary. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Retrospective Studies. Surgical Wound Dehiscence / etiology

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  • (PMID = 20193339.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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66. Imperiale TF, Glowinski EA, Lin-Cooper C, Larkin GN, Rogge JD, Ransohoff DF: Five-year risk of colorectal neoplasia after negative screening colonoscopy. N Engl J Med; 2008 Sep 18;359(12):1218-24
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  • METHODS: We identified persons with no adenomas on baseline screening colonoscopy who returned at 5 years for follow-up colonoscopy.
  • Findings were categorized according to the most advanced lesion present: no polyp, a hyperplastic polyp, a tubular adenoma less than 1 cm in diameter, an advanced adenoma (a tubular adenoma > or = 1 cm in diameter or a polyp with villous histologic features or high-grade dysplasia), or a cancer.
  • RESULTS: Baseline screening colonoscopy had identified 2436 persons with no adenomas; 1256 of them (51.6%) were rescreened a mean (+/-SD) of 5.34+/-1.34 years later.
  • One or more adenomas were found in 201 persons (16.0%).
  • A total of 19 advanced adenomas, of which 10 (52.6%) were distal to the splenic flexure, were found in 16 persons (1.3%).
  • The risk of an advanced adenoma did not differ significantly between persons with no polyps at baseline and those with hyperplastic polyps at baseline (1.1% [12 of 1057] and 2.0% [4 of 199], respectively; P=0.30).
  • Men were more likely than women to have any adenoma (tubular less than 1 cm in diameter or advanced) (relative risk, 1.88; 95% CI, 1.42 to 2.51) and to have an advanced adenoma (relative risk, 3.31; 95% CI, 1.02 to 10.8).
  • The risk of advanced adenoma is also low, although it is higher among men than among women.
  • [MeSH-major] Adenocarcinoma / epidemiology. Adenoma / epidemiology. Colonic Polyps / epidemiology. Colonoscopy. Colorectal Neoplasms / epidemiology

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  • [Copyright] 2008 Massachusetts Medical Society
  • [CommentIn] N Engl J Med. 2008 Dec 11;359(24):2611; author reply 2612 [19090029.001]
  • [CommentIn] N Engl J Med. 2008 Dec 11;359(24):2611; author reply 2612 [19073983.001]
  • [CommentIn] N Engl J Med. 2008 Sep 18;359(12):1285-7 [18799563.001]
  • [CommentIn] N Engl J Med. 2008 Dec 11;359(24):2611-2; author reply 2612 [19090030.001]
  • [ErratumIn] N Engl J Med. 2009 Nov 12;361(20):2004
  • (PMID = 18799558.001).
  • [ISSN] 1533-4406
  • [Journal-full-title] The New England journal of medicine
  • [ISO-abbreviation] N. Engl. J. Med.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / K24 DK02756
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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67. Jin Z, Yin L, Xue L, Lin M, Zheng Q: Anorectal functional results after transanal endoscopic microsurgery in benign and early malignant tumors. World J Surg; 2010 May;34(5):1128-32
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  • BACKGROUND: Transanal endoscopic microsurgery (TEM) has been suggested as a minimally invasive procedure of low morbidity for rectal villous adenomas and early anorectal adenocarcinomas.
  • RESULTS: Of the 37 patients, 24 had villous adenomas and 13 had adenocarcinomas (11 uT1 and 2 uT2).
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Anal Canal / physiopathology. Anus Neoplasms / surgery. Rectal Neoplasms / surgery. Rectum / physiopathology

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  • (PMID = 20225126.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Ramos O Jr, Boguszewski CL, Teixeira S, De Bem R, Parolim B, Prolla JC: Performance of computed tomographic colonography for the screening of colorectal polyp in acromegalic patients: a prospective study. Arq Gastroenterol; 2009 Apr-Jun;46(2):90-6
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  • Computed tomographic colonography, also known as virtual colonoscopy, is an innovative and secure technology which is revolutionizing the diagnosis of colon and rectum neoplasias.
  • The histological analysis of resected lesions revealed 12 tubular adenomas, 6 hyperplastic polyps and 1 colonic tubulo-villous adenoma with an adenocarcinoma focus.
  • In this study, computed tomographic colonography was performed without complications and a complete and safe colorectal evaluation was possible in all acromegalic patients.
  • Moreover, computed tomographic colonography presented good sensitivity, specificity and accuracy for the identification of acromegalic patients with polyps of any size and better results in the diagnosis of large polyps, when they were compared to small polypoid lesions.

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  • [CommentIn] Arq Gastroenterol. 2009 Apr-Jun;46(2):85-6 [19578605.001]
  • (PMID = 19578607.001).
  • [ISSN] 1678-4219
  • [Journal-full-title] Arquivos de gastroenterologia
  • [ISO-abbreviation] Arq Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
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69. Cammarota R, Bertolini V, Pennesi G, Bucci EO, Gottardi O, Garlanda C, Laghi L, Barberis MC, Sessa F, Noonan DM, Albini A: The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker. J Transl Med; 2010;8:112
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  • Since inflammation is associated with cancer progression and angiogenesis, we investigated expression of cytokines like IL-6 and other mediators that play a key role in the innate immune system, in particular toll like receptor 4 (TLR4), in the microenvironment of lesions from different stages of colon disease progression, from ulcerative colitis to adenoma and adenocarcinoma to find useful markers.
  • 116 Archival tissue samples from patients with different stages of colorectal disease: 13 cases of ulcerative colitis (UC), 34 tubular or tubulo-villous adenomas (AD), and 53 infiltrating adenocarcinomas.
  • TLR-4 and IL6 expression in the tumor microenvironment were associated with adenocarcinoma in human samples and in the murine model.
  • We found that adenocarcinoma patients (pT1-4) with higher TLR-4 expression in stromal compartment had a significantly increased risk in disease progression.
  • In those patients with a diagnosis of pT3 (33 cases) colon cancer, those with very high levels of TLR-4 in the tumor stroma relapsed significantly earlier than those with lower expression levels.

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  • [Cites] Gastroenterology. 2008 Apr;134(4):1224-37 [18395100.001]
  • [Cites] Cell Res. 2008 Mar;18(3):334-42 [18301380.001]
  • [Cites] Adv Exp Med Biol. 2008;610:112-27 [18593019.001]
  • [Cites] Adv Cancer Res. 2008;100:203-29 [18620097.001]
  • [Cites] Br J Cancer. 2008 Aug 5;99(3):532-5 [18628760.001]
  • [Cites] BMC Cancer. 2008;8:237 [18702823.001]
  • [Cites] Curr Opin Investig Drugs. 2008 Nov;9(11):1163-70 [18951295.001]
  • [Cites] J Natl Cancer Inst. 2009 Feb 18;101(4):267-76 [19211442.001]
  • [Cites] Am J Pathol. 2009 May;174(5):1972-80 [19349357.001]
  • [Cites] Br J Cancer. 2009 May 19;100(10):1589-602 [19436306.001]
  • [Cites] Curr Pharm Des. 2009;15(18):2095-103 [19519447.001]
  • [Cites] Nat Rev Cancer. 2009 Jul;9(7):489-99 [19536109.001]
  • [Cites] Carcinogenesis. 2009 Jul;30(7):1073-81 [19468060.001]
  • [Cites] Anticancer Res. 2009 Jul;29(7):2473-8 [19596916.001]
  • [Cites] Cancer Res. 2009 Aug 15;69(16):6423-9 [19638594.001]
  • [Cites] J Natl Cancer Inst. 2009 Aug 19;101(16):1110-2 [19671776.001]
  • [Cites] Curr Opin Pharmacol. 2009 Aug;9(4):405-10 [19589728.001]
  • [Cites] Lancet Oncol. 2009 Sep;10(9):877-84 [19656725.001]
  • [Cites] Nat Rev Cancer. 2009 Nov;9(11):798-809 [19851315.001]
  • [Cites] Science. 2010 Jan 15;327(5963):291-5 [20075244.001]
  • [Cites] Oncogene. 2010 Feb 11;29(6):781-8 [19946329.001]
  • [Cites] Br J Cancer. 2010 Mar 2;102(5):908-15 [20145615.001]
  • [Cites] Innate Immun. 2010 Apr;16(2):93-103 [19710105.001]
  • [Cites] Cell Immunol. 2010;263(1):79-87 [20346445.001]
  • [Cites] Hepatology. 2010 Jun;51(6):2172-82 [20513002.001]
  • [Cites] Cancer Res. 2010 Jun 1;70(11):4433-42 [20484034.001]
  • [Cites] Leuk Lymphoma. 2000 Apr;37(3-4):333-9 [10752984.001]
  • [Cites] Cancer Res. 2000 Jul 1;60(13):3333-7 [10910033.001]
  • [Cites] Nature. 2000 Aug 17;406(6797):782-7 [10963608.001]
  • [Cites] J Immunol. 2001 Feb 1;166(3):2018-24 [11160251.001]
  • [Cites] Nat Immunol. 2001 Aug;2(8):675-80 [11477402.001]
  • [Cites] J Pediatr Surg. 2004 Feb;39(2):139-43; discussion 139-43 [14966727.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3522-6 [14993616.001]
  • [Cites] J Cell Physiol. 1985 Jul;124(1):107-12 [3876338.001]
  • [Cites] Cytokine. 1992 Jan;4(1):6-11 [1617157.001]
  • [Cites] Cancer. 1994 Apr 1;73(7):1882-8 [8137215.001]
  • [Cites] Histochem J. 1995 Sep;27(9):689-93 [8557532.001]
  • [Cites] Cell. 1996 Oct 18;87(2):159-70 [8861899.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14833-8 [8962141.001]
  • [Cites] Cancer. 1999 Apr 15;85(8):1670-6 [10223559.001]
  • [Cites] Oncologist. 2005 Jun-Jul;10(6):382-91 [15967832.001]
  • [Cites] Am J Pathol. 2005 Jul;167(1):129-39 [15972959.001]
  • [Cites] Cancer Res. 2005 Dec 1;65(23):10637-41 [16322203.001]
  • [Cites] Nat Rev Cancer. 2006 Jan;6(1):24-37 [16397525.001]
  • [Cites] Science. 2006 Sep 29;313(5795):1960-4 [17008531.001]
  • [Cites] J Investig Dermatol Symp Proc. 2006 Sep;11(1):36-43 [17069009.001]
  • [Cites] Anticancer Res. 2006 Sep-Oct;26(5B):3905-11 [17094421.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Nov;4(11):1351-7 [17059898.001]
  • [Cites] Nat Rev Cancer. 2007 Feb;7(2):139-47 [17218951.001]
  • [Cites] Cancer Res. 2007 Apr 1;67(7):3396-405 [17409450.001]
  • [Cites] Lancet Oncol. 2007 May;8(5):439-43 [17466901.001]
  • [Cites] J Clin Invest. 2007 May;117(5):1155-66 [17476345.001]
  • [Cites] Cancer Res. 2007 Jul 1;67(13):6017-21 [17616656.001]
  • [Cites] Carcinogenesis. 2007 Dec;28(12):2614-23 [17724375.001]
  • [Cites] Gastroenterology. 2007 Dec;133(6):1869-81 [18054559.001]
  • [Cites] Breast Cancer Res. 2007;9(4):212 [17705880.001]
  • [Cites] Cancer Metastasis Rev. 2008 Mar;27(1):31-40 [18087678.001]
  • [Cites] J Exp Med. 2008 Feb 18;205(2):267-70 [18268042.001]
  • [Cites] J Leukoc Biol. 2008 Mar;83(3):493-8 [18160540.001]
  • [Cites] N Engl J Med. 2008 Jun 19;358(25):2704-15 [18565863.001]
  • (PMID = 21059221.001).
  • [ISSN] 1479-5876
  • [Journal-full-title] Journal of translational medicine
  • [ISO-abbreviation] J Transl Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Cytokines; 0 / TLR4 protein, human; 0 / Toll-Like Receptor 4
  • [Other-IDs] NLM/ PMC2997091
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70. Terhaar Sive Droste JS, Craanen ME, van der Hulst RW, Bartelsman JF, Bezemer DP, Cappendijk KR, Meijer GA, Morsink LM, Snel P, Tuynman HA, van Wanrooy RL, Wesdorp EI, Mulder CJ: Colonoscopic yield of colorectal neoplasia in daily clinical practice. World J Gastroenterol; 2009 Mar 7;15(9):1085-92
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  • Advanced neoplasm was defined as adenoma > 10 mm in size, with > 25% villous features or with high-grade dysplasia or cancer.
  • The prevalence of advanced neoplasia was 13%, with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas.
  • Of all patients with right-sided advanced neoplasia (n = 228), 51% had a normal distal colon, whereas 27% had a synchronous distal adenoma.
  • [MeSH-major] Colonic Neoplasms / diagnosis. Colonic Neoplasms / pathology. Colonoscopy / methods. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Adenoma / diagnosis. Adenoma / epidemiology. Adenoma / pathology. Anemia / etiology. Colon / anatomy & histology. Colon / pathology. Functional Laterality. Humans. Netherlands / epidemiology. Prevalence. Weight Loss

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  • [Cites] Gastrointest Endosc. 2000 Jun;51(6):647-51 [10840294.001]
  • [Cites] Gastrointest Endosc. 2006 Dec;64(6):941-7 [17140902.001]
  • [Cites] Scand J Gastroenterol. 2002 May;37(5):568-73 [12059059.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2002 Jul;11(7):660-3 [12101114.001]
  • [Cites] Gastroenterology. 2003 Mar;124(3):608-14 [12612899.001]
  • [Cites] JAMA. 2003 Dec 10;290(22):2959-67 [14665657.001]
  • [Cites] Ann Intern Med. 2003 Dec 16;139(12):959-65 [14678915.001]
  • [Cites] Int J Cancer. 2004 May 1;109(5):777-81 [14999789.001]
  • [Cites] Eur J Cancer. 2004 Mar;40(5):638-42 [15010063.001]
  • [Cites] Am J Gastroenterol. 2004 Mar;99(3):472-7 [15056088.001]
  • [Cites] Ann Intern Med. 2004 Aug 17;141(4):264-71 [15313742.001]
  • [Cites] J Clin Pathol. 1982 Aug;35(8):830-41 [7107955.001]
  • [Cites] N Engl J Med. 1992 Mar 5;326(10):658-62 [1736104.001]
  • [Cites] Am J Gastroenterol. 1995 Mar;90(3):353-65 [7872270.001]
  • [Cites] Gastrointest Endosc. 1997 Dec;46(6):492-6 [9434214.001]
  • [Cites] Eur J Cancer Prev. 2004 Aug;13(4):257-62 [15554552.001]
  • [Cites] Cell Oncol. 2005;27(1):17-29 [15750204.001]
  • [Cites] Gastrointest Endosc. 2005 Apr;61(4):547-53 [15812407.001]
  • [Cites] J Med Screen. 2005;12(1):28-32 [15814016.001]
  • [Cites] Lancet Oncol. 2005 Nov;6(11):871-6 [16257795.001]
  • [Cites] Gastrointest Endosc. 2005 Dec;62(6):875-83 [16301030.001]
  • [Cites] JAMA. 2006 May 24;295(20):2357-65 [16720821.001]
  • [Cites] Gastrointest Endosc. 2006 Nov;64(5):751-9 [17055869.001]
  • [Cites] N Engl J Med. 2006 Nov 2;355(18):1863-72 [17079760.001]
  • [Cites] N Engl J Med. 2006 Dec 14;355(24):2533-41 [17167136.001]
  • [Cites] Cell Oncol. 2007;29(1):19-24 [17429138.001]
  • [Cites] Int J Cancer. 2008 May 1;122(9):2106-14 [18183593.001]
  • [Cites] CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96 [18287387.001]
  • [Cites] Colorectal Dis. 2008 Sep;10(7):708-14 [17956587.001]
  • [Cites] Gastroenterol Clin Biol. 2002 Mar;26(3):220-4 [11981461.001]
  • (PMID = 19266601.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2655182
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71. Carneiro FP, Ramalho LN, Britto-Garcia S, Ribeiro-Silva A, Zucoloto S: Immunohistochemical expression of p16, p53, and p63 in colorectal adenomas and adenocarcinomas. Dis Colon Rectum; 2006 May;49(5):588-94
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  • [Title] Immunohistochemical expression of p16, p53, and p63 in colorectal adenomas and adenocarcinomas.
  • PURPOSE: The aim of this study was to investigate the immunohistochemical expression of p16, p53, and p63 proteins according to some pathologic parameters related to colorectal adenomas and adenocarcinomas such as grade of dysplasia and histologic type.
  • METHODS: Immunohistochemistry with the antibodies p16, p53, and p63 was performed in tubular, tubular-villous, and villous adenomas (n = 30) and in well, moderately, and poorly differentiated adenocarcinomas (n = 30).
  • RESULTS: The p16 and p53 labelings were observed in some adenomas and adenocarcinomas but without any association with p63 expression, histologic type, or grade of differentiation of the neoplasm.
  • P63 expression was found mainly in the villous adenomas and in the poorly differentiated adenocarcinomas.
  • The poorly differentiated adenocarcinomas also exhibited coexpression of CK5 and p63.
  • However, p63 expression was closely associated with villous adenomas and poorly differentiated adenocarcinomas.
  • [MeSH-minor] Adenocarcinoma. Adenoma. Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. DNA-Binding Proteins. Genes, Tumor Suppressor. Humans. Immunohistochemistry. Keratins / metabolism. Transcription Factors. Tumor Suppressor Proteins

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  • (PMID = 16575619.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / Phosphoproteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 68238-35-7 / Keratins
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72. Pérez R, Lasa A, Toro DH, Cruz-Correa M, Martinez-Souss J: Relationship between sporadic hyperplastic polyps and colorectal neoplasia in Hispanic veterans. P R Health Sci J; 2010 Dec;29(4):372-6
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  • METHODS: The study consisted of a retrospective review of all the medical records of patients who underwent a colonoscopy for the first time during the calendar year 2005 and had a pathologic diagnosis of HP, tubular adenoma (TA), tubulovillous adenoma (TVA), villous adenoma (VA) and/or colon adenocarcinoma at the VA Caribbean Healthcare System.
  • Histologic evaluation of lesions revealed: 121 patients who had HP, 331 with TA, 33 with TVA, 12 with VA, 13 with serrated adenomas and 61 patients had adenocarcinoma.
  • Univariate analysis revealed that patients with HP appeared to have a lower likelihood of having TA (p < 0.001), adenocarcinoma (p = 0.002), and CRN in general (P < 0.001) as compared to patients without HP.
  • Multivariate analysis with logistic regression revealed that patients with HP had a significantly lower likelihood of having TA (adjusted OR = 0.21; 95% CI 0.12-0.37), and adenocarcinoma (adjusted OR = 0.33; 95% CI 0.15-0.73) compared to patients without HP.


73. Henry ZH, Yeaton P, Shami VM, Kahaleh M, Patrie JT, Cox DG, Peura DA, Emura F, Wang AY: Meshed capillary vessels found on narrow-band imaging without optical magnification effectively identifies colorectal neoplasia: a North American validation of the Japanese experience. Gastrointest Endosc; 2010 Jul;72(1):118-26
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • NBI colonoscopy without optical magnification for neoplastic polyp diagnosis appears to be comparable with NBI with optical magnification when the MC pattern is used.
  • [MeSH-major] Adenocarcinoma / blood supply. Adenoma, Villous / diagnosis. Capillaries / pathology. Carcinoma, Squamous Cell / blood supply. Colonic Polyps / diagnosis. Colonoscopy. Colorectal Neoplasms / blood supply
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Colon / blood supply. Colon / pathology. Diagnosis, Differential. Female. Humans. Japan. Male. Middle Aged. Neoplasm Staging. Rectum / blood supply. Rectum / pathology. Sensitivity and Specificity. United States

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  • [Copyright] Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20381799.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] United States
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74. Agaimy A, Märkl B, Arnholdt H, Hartmann A, Schneider-Stock R, Chetty R: Sporadic segmental Interstitial cell of cajal hyperplasia (microscopic GIST) with unusual diffuse longitudinal growth replacing the muscularis propria: differential diagnosis to hereditary GIST syndromes. Int J Clin Exp Pathol; 2010;3(5):549-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sporadic segmental Interstitial cell of cajal hyperplasia (microscopic GIST) with unusual diffuse longitudinal growth replacing the muscularis propria: differential diagnosis to hereditary GIST syndromes.
  • Case 1 was a 59-yr-old woman who presented with signs of ileus and a large mass submitted as Meckel diverticulum.
  • Case 2 was a 66-yr-old man who underwent segmental sigmoid colon resection for adenocarcinoma in a villous adenoma.
  • [MeSH-minor] Aged. Diagnosis, Differential. Digestive System Surgical Procedures. Female. Humans. Hyperplasia. Male. Middle Aged. Polymerase Chain Reaction. Proto-Oncogene Proteins c-kit / genetics

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  • [Cites] Am J Surg Pathol. 2000 Feb;24(2):326-7 [10680913.001]
  • [Cites] Virchows Arch. 2009 Aug;455(2):101-8 [19572146.001]
  • [Cites] Mod Pathol. 2002 Feb;15(2):125-36 [11850541.001]
  • [Cites] Am J Pathol. 2002 May;160(5):1567-72 [12000708.001]
  • [Cites] Gut. 2002 Dec;51(6):793-6 [12427778.001]
  • [Cites] Science. 2003 Jan 31;299(5607):708-10 [12522257.001]
  • [Cites] J Pathol. 2004 Jan;202(1):80-5 [14694524.001]
  • [Cites] Gastroenterology. 2004 Jan;126(1):318-21 [14699510.001]
  • [Cites] Clin Cancer Res. 2004 May 1;10(9):3076-81 [15131046.001]
  • [Cites] J Mol Diagn. 2004 Aug;6(3):197-204 [15269295.001]
  • [Cites] Am J Surg Pathol. 1993 Jul;17(7):706-14 [8317611.001]
  • [Cites] Science. 1998 Jan 23;279(5350):577-80 [9438854.001]
  • [Cites] Am J Pathol. 1998 May;152(5):1259-69 [9588894.001]
  • [Cites] Cancer. 2005 Feb 15;103(4):821-9 [15648083.001]
  • [Cites] Am J Surg Pathol. 2006 Jan;30(1):90-6 [16330947.001]
  • [Cites] Virchows Arch. 2006 Mar;448(3):288-94 [16308708.001]
  • [Cites] Langenbecks Arch Surg. 2006 Aug;391(4):322-9 [16402273.001]
  • [Cites] Hum Pathol. 2006 Dec;37(12):1527-35 [16996566.001]
  • [Cites] Semin Diagn Pathol. 2006 May;23(2):70-83 [17193820.001]
  • [Cites] Am J Surg Pathol. 2007 Jan;31(1):113-20 [17197927.001]
  • [Cites] Histopathology. 2007 Jan;50(2):190-202 [17222247.001]
  • [Cites] Am J Surg Pathol. 2007 Jun;31(6):933-7 [17527083.001]
  • [Cites] Pathology. 2008 Jan;40(1):9-12 [18038309.001]
  • [Cites] Am J Surg Pathol. 2007 Nov;31(11):1629-35 [18059218.001]
  • [Cites] Endoscopy. 2007 Feb;39 Suppl 1:E142-3 [17611891.001]
  • [Cites] Int J Cancer. 2008 May 1;122(9):2160-4 [18183595.001]
  • [Cites] Am J Surg Pathol. 2008 Jun;32(6):867-73 [18408593.001]
  • [Cites] Am J Surg Pathol. 2008 Oct;32(10):1553-9 [18724245.001]
  • [Cites] World J Surg Oncol. 2009;7:33 [19309498.001]
  • [Cites] JBR-BTR. 2009 Jan-Feb;92(1):23-4 [19358482.001]
  • [Cites] Am J Surg Pathol. 2000 Nov;24(11):1568-72 [11075862.001]
  • (PMID = 20606738.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  • [Other-IDs] NLM/ PMC2897106
  • [Keywords] NOTNLM ; GIST / ICC hyperplasia / KIT mutation / Meckel Diverticulum / hereditary GIST
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75. Pokala N, Delaney CP, Kiran RP, Brady K, Senagore AJ: Outcome of laparoscopic colectomy for polyps not suitable for endoscopic resection. Surg Endosc; 2007 Mar;21(3):400-3
MedlinePlus Health Information. consumer health - Colonic Polyps.

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  • Mean polyp size was 3.1 cm, and pathology revealed tubular (n = 14), tubulovillous (n = 33) and villous adenoma (n = 2), pseudopolyp (n = 1), and prolapse of the appendix into the cecum mimicking an adenoma (n = 1).
  • High-grade dysplasia was seen in four tubular (33%) and five tubulovillous adenomas (15.5%).
  • Adenocarcinoma not identified at colonoscopy was found in 11 polyps (20%), 9 tubulovillous (27.8%) and both villous adenomas (100%).

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  • (PMID = 17180271.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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76. Ghidirim G, Mişin I, Istrate V, Cazacu S: Endoscopic papillectomy into the treatment of neoplastic lesions of vater papilla. Curr Health Sci J; 2009 Apr;35(2):92-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenomas of the duodenal papilla are rare.
  • The frequency of malignant adenomas is 15-30%.
  • Villous adenoma is a premalignant lesion with the highest rate of transformation.
  • AIM: Evaluation of the efficacy and safety of endoscopic papillectomy for ampullary adenomas.
  • MATERIAL AND METHOD: 12 patients were selected (F:M, 5:7, age range 37 - 68 years) with ampullary adenoma, treated by endoscopic papillectomy.
  • RESULTS: En bloc resection was performed in 8 cases, and piecemeal resection in 4 cases.
  • Pathology examination has show: tubulo-villous adenoma (5 patients); villous adenoma (4 patients), tubular adenoma (2 cases), adenocarcinoma (one case).
  • CONCLUSION: Endoscopic papillectomy is a safe and well-tolerated alternative to surgical treatment of ampullary adenoma.

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  • (PMID = 24778815.001).
  • [ISSN] 2067-0656
  • [Journal-full-title] Current health sciences journal
  • [ISO-abbreviation] Curr Health Sci J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
  • [Other-IDs] NLM/ PMC3945241
  • [Keywords] NOTNLM ; Vater papilla / ampullary adenoma / bleeding / endoscopic papillectomy / pancreatitis / sphyncterotomy
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77. Miura T, Igarashi Y, Okano N, Miki K, Okubo Y: Endoscopic diagnosis of intraductal papillary-mucinous neoplasm of the pancreas by means of peroral pancreatoscopy using a small-diameter videoscope and narrow-band imaging. Dig Endosc; 2010 Apr;22(2):119-23
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  • [Title] Endoscopic diagnosis of intraductal papillary-mucinous neoplasm of the pancreas by means of peroral pancreatoscopy using a small-diameter videoscope and narrow-band imaging.
  • BACKGROUND: Intraductal papillary-mucinous neoplasm (IPMN) is an intraductal tumor in which the mucin-producing epithelium shows proliferated papillary and a wide variety of pathological changes ranging from hyperplasia to adenocarcinoma.
  • We carried out the differential diagnosis of benign lesion to malignant lesion.
  • METHODS: Between April 2003 and May 2009, PPS using a small-diameter videoscope by means of NBI was carried out on 21 hospitalized patients with IPMN (10 cases of adenocarcinoma, 11 cases of adenoma or hyperplasia; 14 males and seven females, with a mean age of 69.4 years).
  • RESULTS: Fifteen focal lesions of the 16 cases in the head of the pancreas (93.7%) and four focal lesions of the five cases in the pancreatic body (80%) were observable, whereas two lesions (adenocarcinoma in the pancreatic body, and adenoma in the uncus of pancreas) were not observable.
  • Endoscopically, seven cases were classified as villous type and two cases as vegetative type, and nine cases were diagnosed as adenocarcinoma.
  • Ten cases with sessile type or semipedunculated type were diagnosed as adenoma or hyperplasia.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Endoscopes. Endoscopy, Digestive System / instrumentation. Pancreatic Ducts. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Equipment Design. Female. Humans. Hyperplasia / diagnosis. Male

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  • (PMID = 20447205.001).
  • [ISSN] 1443-1661
  • [Journal-full-title] Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
  • [ISO-abbreviation] Dig Endosc
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] Australia
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78. Alper M, Cukur S, Belenli O, Suna M: Evaluation of the immunohistochemical stain patterns of survivin, Bak and Bag-1 in colorectal cancers and comparison with polyps situated in the colon. Hepatogastroenterology; 2008 Jul-Aug;55(85):1269-73
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  • The adenoma-carcinoma sequence in colorectal cancer has been documented approximately; however, several series of molecular mechanisms still require elucidation.
  • METHODOLOGY: Fifteen colonoscopic biopsy and 25 colectomy colorectal cancer samples, 12 hyperplastic colon polyps, and 18 tubular and 19 villous adenoma cases were studied.
  • [MeSH-major] Adenocarcinoma / metabolism. Colonic Neoplasms / metabolism. Colonic Polyps / metabolism. DNA-Binding Proteins / metabolism. Microtubule-Associated Proteins / metabolism. Neoplasm Proteins / metabolism. Transcription Factors / metabolism. bcl-2 Homologous Antagonist-Killer Protein / metabolism

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  • (PMID = 18795671.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / BAK1 protein, human; 0 / BCL2-associated athanogene 1 protein; 0 / BIRC5 protein, human; 0 / DNA-Binding Proteins; 0 / Inhibitor of Apoptosis Proteins; 0 / Microtubule-Associated Proteins; 0 / Neoplasm Proteins; 0 / Transcription Factors; 0 / bcl-2 Homologous Antagonist-Killer Protein
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79. Selvindos PB, Ho YH: Multimedia article. Laparoscopic ultralow anterior resection with colonic J-pouch-anal anastomosis. Dis Colon Rectum; 2008 Nov;51(11):1710-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients with adenocarcinoma underwent preoperative endorectal ultrasound to individualize for neoadjuvant chemoradiotherapy, based on local extent and lymph nodes seen.
  • The indications were adenocarcinoma (n = 51), squamous-cell carcinoma of rectum (n = 1), dermoid tumor of mesorectum (n = 1), large villous adenoma (n = 1), and carcinoid with local lymph node metastases (n = 1).
  • The adenocarcinomas were a median distance of 6 (3-12) cm from the anal verge.
  • The histologic grading or the adenocarcinoma patients were: Stage I, n = 14; Stage II, n = 23; Stage III, n = 11; Stage IV, n = 3.
  • At a median follow-up of 14 (2-33) months, none of the adenocarcinoma patients who had undergone curative resection had recurrences.
  • [MeSH-major] Adenocarcinoma / surgery. Anal Canal / surgery. Colonic Pouches. Laparoscopy / methods. Proctocolectomy, Restorative / methods. Rectal Neoplasms / surgery

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  • (PMID = 18679748.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Interactive Tutorial
  • [Publication-country] United States
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80. Zuo ZG, Song HY, Xu C, Li J, Ni SC, Chen SQ: [Combination of trans-anal intersphincteric resection and trans-abdominal total mesorectal excision for anus-retained ultra-low rectal tumors]. Zhonghua Wai Ke Za Zhi; 2009 Jul 1;47(13):988-91

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • For pathological types, there were 23 cases of adenocarcinoma (9 well differentiated and 14 moderately differentiated), 1 papillary carcinoma, 2 rectal stromal tumor, 5 rectal villous adenoma with neoplasia and 3 giant villous adenoma.

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  • (PMID = 19957808.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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81. Meneghetti AT, Safadi B, Stewart L, Way LW: Local resection of ampullary tumors. J Gastrointest Surg; 2005 Dec;9(9):1300-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Preoperative biopsies (obtained in all patients) showed 18 adenomas, four adenomas with dysplasia, five adenomas with atypia, one adenoma with dysplasia and focal adenocarcinoma, and two tumors seen on endoscopy, whose biopsies showed only duodenal mucosa.
  • The final pathologic diagnosis was 23 villous adenomas, six adenocarcinomas, and one paraganglioma.
  • On preoperative biopsies, all patients who had high-grade dysplasia and one of five patients with atypia turned out to have invasive adenocarcinoma when the entire specimen was examined postoperatively.
  • Two (33%) adenocarcinomas recurred at a mean of 4 years; both had negative margins at the initial resection.
  • Among the 23 adenomas, three (13%) recurred (all as adenomas) at a mean of 3.2 years; in only one of these cases was the margin positive at the time of resection.
  • Ampullary adenomas can be resected locally with good results, but the recurrence rate was 13%, so endoscopic surveillance is indicated postoperatively.
  • No adenomas recurred as carcinomas, suggesting that local resection is appropriate for these tumors in the absence of dysplasia or atypia on preoperative biopsies.

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  • (PMID = 16332486.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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82. Gimeno-García AZ, Ramírez F, Gonzalo V, Balaguer F, Petit A, Pellisé M, Llach J, Bordas JM, Piqué JM, Castells A: [High-grade dysplasia as a risk factor of metachronous advanced colorectal neoplasms in patients with advanced adenomas]. Gastroenterol Hepatol; 2007 Apr;30(4):207-11
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  • [Title] [High-grade dysplasia as a risk factor of metachronous advanced colorectal neoplasms in patients with advanced adenomas].
  • [Transliterated title] Displasia de alto grado como factor de riesgo de neoplasia colorrectal avanzada metacrónica, en pacientes con adenomas avanzados.
  • BACKGROUND: Patients with advanced adenomas (AA) have a high risk of developing advanced colorectal neoplasms.
  • However, its predictive value for developing advanced neoplams in patients with advanced adenoma is unknown.
  • The number of metachronic polyps (p = 0.67), adenomas (p = 0.73), AA (p = 0.93) and AA with HGD (p = 0.88) was also similar.
  • CONCLUSION: The risk of developing advanced neoplasms is not different between AA with HGD and those with other characteristics of AA (villous pattern and larger than 1 cm).
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Colonic Polyps / pathology. Colonoscopy / methods. Colorectal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Precancerous Conditions / pathology

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  • (PMID = 17408548.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
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83. Nieuwenhuis DH, Draaisma WA, Verberne GH, van Overbeeke AJ, Consten EC: Transanal endoscopic operation for rectal lesions using two-dimensional visualization and standard endoscopic instruments: a prospective cohort study and comparison with the literature. Surg Endosc; 2009 Jan;23(1):80-6
MedlinePlus Health Information. consumer health - Endoscopy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Between 2004 and 2006, 31 patients with a median age of 75 years (range, 33-87 years) underwent 31 TEOs for a total of 36 rectal lesions (29 tubulovillous adenomas and 7 adenocarcinomas).
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Endoscopes. Endoscopy. Rectal Neoplasms / surgery. Surgery, Computer-Assisted / instrumentation

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  • (PMID = 18443874.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] Germany
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84. Hetzel JT, Huang CS, Coukos JA, Omstead K, Cerda SR, Yang S, O'Brien MJ, Farraye FA: Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol; 2010 Dec;105(12):2656-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Polyps were classified as adenoma (tubular, tubulovillous, or villous), serrated polyp (hyperplastic polyp (HP), sessile serrated adenoma (SSA), or dysplastic serrated polyp (DSP)), adenocarcinoma, or other.
  • Detection prevalence (patients with at least one polyp per 100 colonoscopies) was 22.2 for adenomas, 11.7 for HP, 0.6 for SSA, and 0.2 for DSP.
  • Detection prevalences among endoscopists differed significantly for adenomas, HP, and SSA.
  • Classification rates among pathologists differed significantly for HP and SSA, but not for adenoma or DSP.
  • On multivariate analysis, endoscopist was a significant predictor of adenoma, HP, and SSA.
  • Pathologist was a significant predictor of HP, SSA, and DSP, but not adenoma.
  • Detection of adenoma, HP, and SSA differed significantly by endoscopist.


85. Andreeva IuIu, Zavalishina LE, Frank GA: [Classification of urinary bladder tumors]. Arkh Patol; 2006 Sep-Oct;68(5):46-53
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  • Difficulties in the microscopic diagnosis of different types of urothelial carcinoma, the specific features of gradation and staging, and possibilities of differential diagnosis are presented.
  • [MeSH-minor] Adenocarcinoma, Clear Cell / classification. Adenocarcinoma, Clear Cell / pathology. Adenoma, Villous / classification. Adenoma, Villous / pathology. Carcinoma, Papillary / classification. Carcinoma, Papillary / pathology. Carcinoma, Small Cell / classification. Carcinoma, Small Cell / pathology. Carcinoma, Squamous Cell / classification. Carcinoma, Squamous Cell / pathology. Carcinoma, Transitional Cell / classification. Carcinoma, Transitional Cell / pathology. Humans. Urothelium / pathology. World Health Organization

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  • (PMID = 17144533.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Lectures
  • [Publication-country] Russia (Federation)
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86. Li D, Jin C, McCulloch C, Kakar S, Berger BM, Imperiale TF, Terdiman JP: Association of large serrated polyps with synchronous advanced colorectal neoplasia. Am J Gastroenterol; 2009 Mar;104(3):695-702
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: Serrated polyps of the colorectum are a histologically and genetically heterogeneous group of lesions, which include classic hyperplasic polyps, sessile serrated adenomas (SSAs), and traditional serrated adenomas.
  • METHODS: Among 4,714 asymptomatic subjects who underwent screening colonoscopy, cases of advanced colorectal neoplasia (tubular adenoma > or =1 cm, adenoma with any villous histology, adenoma with carcinoma in situ / high-grade dysplasia, or invasive adenocarcinoma) were compared with controls without advanced neoplasia with respect to candidate predictors, including age, sex, family history of colorectal cancer, body mass index, the presence and number of small tubular adenomas (<1 cm), the presence of multiple small serrated polyps (<1 cm), and the presence of large serrated polyps (> or =1 cm).
  • RESULTS: Among 467 cases and 4,247 controls, independent predictors of advanced colorectal neoplasia were increasing age (odds ratio (OR)=4.51; 95% confidence interval (CI), 1.43-14.3; P=0.01 for subjects > or =80 years vs. 50-54 years of age); non-advanced tubular adenomas (OR=2.33; 95% CI 1.37-3.96, P=0.0017 for 3 or more); and large serrated polyps (OR=3.24; 95% CI 2.05-5.13, P<0.0001).

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  • (PMID = 19223889.001).
  • [ISSN] 1572-0241
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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87. Kim DH, Kim JW, Cho JH, Baek SH, Kakar S, Kim GE, Sleisenger MH, Kim YS: Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum. Int J Oncol; 2005 Oct;27(4):957-64
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  • To examine the relationship between subsets of colorectal polyps and non-mucinous and mucinous adenocarcinomas of the colorectum, we evaluated the frequency of the expression of cell lineage associated mucin core proteins (MUC5AC and MUC2), trefoil factors (TFF1 and TFF3), and APC and p21 in these tissues.
  • An immunohistochemical study was performed in 10 normal rectal mucosa samples (NM) 21 hyperplastic polyps (HP), 20 serrated adenomas (SA), 25 tubular adenomas (TA), 13 tubulovillous adenomas (TVA), 7 villous adenomas (VA), 42 non-mucinous colorectal cancers (NMC), and 19 mucinous colorectal cancers (MC).
  • Our results showed that MUC2 expression and de novo ectopic expression of MUC5AC and TFF1 are more frequent in HP, SA, TVA, VA, and MC than in TA and NMC.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenocarcinoma, Mucinous / metabolism. Adenomatous Polyposis Coli Protein / biosynthesis. Colorectal Neoplasms / metabolism. Gene Expression Regulation, Neoplastic. Mucins / chemistry. Peptides / metabolism. Proto-Oncogene Proteins p21(ras) / biosynthesis. Tumor Suppressor Proteins / metabolism
  • [MeSH-minor] Adenoma / metabolism. Cell Differentiation. Cell Line, Tumor. Cell Lineage. Cell Nucleus / metabolism. Cytoplasm / metabolism. Humans. Immunohistochemistry. Mucin 5AC. Mucin-2

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  • (PMID = 16142311.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Adenomatous Polyposis Coli Protein; 0 / MUC2 protein, human; 0 / MUC5AC protein, human; 0 / Mucin 5AC; 0 / Mucin-2; 0 / Mucins; 0 / Peptides; 0 / TFF1 protein, human; 0 / TFF3 protein, human; 0 / Tumor Suppressor Proteins; EC 3.6.5.2 / Proto-Oncogene Proteins p21(ras)
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88. Barreda B F, Combe G J, Valdez P LA, Sánchez L J: [Clinical aspects in polyps of the colon]. Rev Gastroenterol Peru; 2007 Apr-Jun;27(2):131-47
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  • [Transliterated title] Aspectos clínicos de los pólipos colónicos.
  • MATERIAL AND METHODS: The revision of clinical histories of 840 patients with the diagnosis of colon polyp was made who attended the service of Gastroenterology of the INEN between the 1 of January from 1974 to the 31 of March of 2004 and a card predesigned for each clinical history filled.
  • 156 patients by diagnosis related to cancer and familiar adenomatouspoliposis did not include themselves.
  • Within the histology of the 1057 polyps, 331 was briefed (31.3%) that were hyperplasic, 448 (42.4%) adenomas, 278 (26.3%) others and 35 (8.2%) adenocarcinomas on adenomas.
  • The location but frequence of the adenomas was in the left colon (76.6%).
  • Adenocarcinoma (carcinomas on adenomas), was present mainly in polyps villous type, with dysplasia severe and greater to 10 mm.
  • The carcinoma is more probable with severe dysplasia and greater size of the adenoma.

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  • (PMID = 17712391.001).
  • [ISSN] 1022-5129
  • [Journal-full-title] Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
  • [ISO-abbreviation] Rev Gastroenterol Peru
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Peru
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89. Ruffolo C, Scarpa M, Polese L, Angriman I: Adenocarcinoma after restorative proctocolectomy for cancer in ulcerative colitis. Int J Colorectal Dis; 2007 Dec;22(12):1557-8
MedlinePlus Health Information. consumer health - Ulcerative Colitis.

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  • [Title] Adenocarcinoma after restorative proctocolectomy for cancer in ulcerative colitis.
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / diagnosis. Colitis, Ulcerative / complications. Colonic Neoplasms / surgery. Proctocolectomy, Restorative

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  • (PMID = 17279349.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
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