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1. Brunelli M, Gobbo S, Cossu-Rocca P, Cheng L, Ficarra V, Novara G, Menestrina F, Chilosi M, Martignoni G: Fluorescent cytogenetics of renal cell neoplasms. Pathologica; 2008 Dec;100(6):454-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The genetics of these tumours may aid in correct diagnosis and accurate assessment of prognosis.
  • Fluorescence in situ hybridization (FISH) on formalin-fixed, paraffin-embedded tissue is an increasingly useful technique in the detection of many diagnostic chromosomal abnormalities, among which chromosomes 1, 2, 3p, 6, 7, 10, 17 and Y are the most common.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. In Situ Hybridization, Fluorescence. Kidney Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / genetics. Adenocarcinoma, Mucinous / pathology. Adenoma / diagnosis. Adenoma / genetics. Adenoma / pathology. Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / genetics. Adenoma, Oxyphilic / pathology. Adult. Aneuploidy. Carcinoma, Papillary / diagnosis. Carcinoma, Papillary / genetics. Carcinoma, Papillary / pathology. Child. Chromosome Aberrations. Chromosomes, Human / ultrastructure. Chromosomes, Human, X / ultrastructure. Humans. Kidney Failure, Chronic / complications. Translocation, Genetic

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  • (PMID = 19475886.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 54
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2. Caputi Iambrenghi O, Ugenti I, Martines G, Marino F, Francesco Altomare D, Memeo V: Endoscopic management of large colorectal polyps. Int J Colorectal Dis; 2009 Jul;24(7):749-53
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  • At histology, most of polyps (131) were adenomas (nine with adenocarcinoma in situ).

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  • [Cites] Gastrointest Endosc. 1996 Mar;43(3):256-7 [8857147.001]
  • [Cites] Gastrointest Endosc. 1997 Oct;46(4):387-9 [9351059.001]
  • [Cites] Dis Colon Rectum. 1984 Nov;27(11):726-9 [6499606.001]
  • [Cites] Am J Gastroenterol. 1987 Jul;82(7):615-8 [3605021.001]
  • [Cites] Gastrointest Endosc. 1996 Mar;43(3):189-95 [8857132.001]
  • [Cites] Gastrointest Endosc. 1998 Jun;47(6):496-9 [9647375.001]
  • [Cites] Am Fam Physician. 1975 Sep;12 (3):125-32 [1163409.001]
  • [Cites] Am J Clin Pathol. 1974 Oct;62(4):447-54 [4416491.001]
  • [Cites] J Clin Oncol. 2000 May;18(9):1967-79 [10784639.001]
  • [Cites] Gastrointest Endosc. 2002 Mar;55(3):371-5 [11868011.001]
  • [Cites] Dis Colon Rectum. 2001 Jan;44(1):112-8 [11805571.001]
  • [Cites] World J Surg. 2000 Sep;24(9):1036-46 [11036279.001]
  • [Cites] Endoscopy. 2005 Nov;37(11):1116-22 [16281142.001]
  • [Cites] Gastrointest Endosc. 1989 Nov-Dec;35(6):536-40 [2689263.001]
  • [Cites] Gastrointest Endosc. 1999 Jan;49(1):113-5 [9869736.001]
  • [Cites] Gastrointest Endosc. 1998 Nov;48(5):477-84 [9831835.001]
  • [Cites] Br J Surg. 2002 Aug;89(8):1020-4 [12153628.001]
  • [Cites] Am J Surg. 1977 Dec;134(6):770-1 [596545.001]
  • [Cites] Gastrointest Endosc. 2005 Jan;61(1):1-7 [15672048.001]
  • [Cites] Gastrointest Endosc. 1996 Mar;43(3):183-8 [8857131.001]
  • [Cites] Dis Colon Rectum. 2003 Nov;46(11):1513-6 [14605571.001]
  • [Cites] World J Surg. 2000 Sep;24(9):1081-90 [11036286.001]
  • [Cites] Cancer. 1975 Dec;36(6):2251-70 [1203876.001]
  • [Cites] Int Abstr Surg. 1958 Jun;106(6):519-38 [13556509.001]
  • [Cites] ANZ J Surg. 2003 Dec;73(12):988-95 [14632888.001]
  • [Cites] Gastrointest Endosc. 1999 Jun;49(6):731-5 [10343218.001]
  • [Cites] J Clin Gastroenterol. 1992 Dec;15(4):347-51 [1294644.001]
  • (PMID = 19259689.001).
  • [ISSN] 1432-1262
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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3. Popnikolov NK, Cavone SM, Schultz PM, Garcia FU: Diagnostic utility of p75 neurotrophin receptor (p75NTR) as a marker of breast myoepithelial cells. Mod Pathol; 2005 Dec;18(12):1535-41
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  • The staining pattern was compared to those of myosin heavy chain and p63. p75NTR immunostain was consistently positive and compatible with p63 and myosin immunoreactivity in the myoepithelial cells of the normal mammary gland, benign breast lesions (six usual ductal hyperplasias, six specimens with sclerosing adenosis, eight intraductal papillomas, six fibroadenomas), and carcinoma in situ (18 ductal carcinomas in situ, two noninvasive papillary carcinomas, two lobular carcinomas in situ).
  • No p75NTR expression was found in the malignant cells in all in situ carcinomas, invasive lobular carcinomas (n = 11), tubular carcinomas (n = 10), invasive papillary carcinomas (n = 6), mucinous carcinomas (n = 4), and medullary carcinomas (n = 2).
  • Our study shows that p75NTR is a useful marker for breast myoepithelial cells and can be used to rule out invasive disease as well as to evaluate difficult for diagnosis sclerosing lesions.
  • [MeSH-major] Adenocarcinoma / pathology. Biomarkers, Tumor / metabolism. Breast / pathology. Breast Neoplasms / pathology. Epithelial Cells / pathology. Muscle, Smooth / pathology. Receptor, Nerve Growth Factor / metabolism
  • [MeSH-minor] Carcinoma in Situ / metabolism. Carcinoma in Situ / pathology. Carcinoma, Intraductal, Noninfiltrating / metabolism. Carcinoma, Intraductal, Noninfiltrating / pathology. Carcinoma, Lobular / metabolism. Carcinoma, Lobular / pathology. Female. Fibroadenoma / metabolism. Fibroadenoma / pathology. Fibrocystic Breast Disease / metabolism. Fibrocystic Breast Disease / pathology. Humans. Hyperplasia / metabolism. Hyperplasia / pathology. Immunoenzyme Techniques. Myosin Heavy Chains / metabolism. Papilloma, Intraductal / metabolism. Papilloma, Intraductal / pathology

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  • (PMID = 16258511.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptor, Nerve Growth Factor; EC 3.6.4.1 / Myosin Heavy Chains
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4. Janot MS, Kersting S, Chromik AM, Tannapfel A, Uhl W: [Amyloidosis of the small intestine following whipple operation is a rare cause of chronic ileus and has to be considered as differential diagnosis]. Zentralbl Chir; 2010 Aug;135(4):345-9
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  • [Title] [Amyloidosis of the small intestine following whipple operation is a rare cause of chronic ileus and has to be considered as differential diagnosis].
  • In this paper we report that secondary amyloidosis of the small intestine can produce similar symptoms and has to be evaluated as a rare differential diagnosis in chronic ileus.
  • In two patients surgery was performed due to carcinoma in situ and in one patient due to benign cystadenoma of the pancreas.
  • Surprisingly, the intraoperative situs did not show any tumour growth.
  • Surgeons have to keep in mind that amyloidosis is a possible differential diagnosis in addition to relapse of tumour growth and peritoneal carcinomatosis in these patients.
  • [MeSH-major] Adenocarcinoma, Papillary / surgery. Amyloidosis / diagnosis. Cystadenoma, Mucinous / surgery. Ileus / diagnosis. Intestinal Diseases / diagnosis. Intestine, Small. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy. Postoperative Complications / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Chronic Disease. Diagnosis, Differential. Fatal Outcome. Female. Humans. Male. Tissue Adhesions / diagnosis. Tissue Adhesions / pathology. Tissue Adhesions / surgery

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  • [Copyright] Georg Thieme Verlag Stuttgart ˙ New York.
  • (PMID = 20464655.001).
  • [ISSN] 1438-9592
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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5. Tanaka K, Komoike Y, Egawa C, Motomura K, Koyama H, Nagumo S, Kataoka TR, Inaji H: Indeterminate calcification and clustered cystic lesions are strongly predictive of the presence of mucocele-like tumor of the breast: a report of six cases. Breast Cancer; 2009;16(1):77-82
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  • Moreover, MLT is often accompanied by atypical ductal hyperplasia (ADH) or ductal carcinoma in situ (DCIS), and preoperative diagnosis is very confusing.
  • Ultimately, excisional biopsies were performed to obtain a correct diagnosis in all cases.
  • [MeSH-minor] Adenocarcinoma, Mucinous / pathology. Adult. Biopsy, Fine-Needle. Carcinoma in Situ / pathology. Carcinoma, Ductal, Breast / pathology. Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 18478314.001).
  • [ISSN] 1880-4233
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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6. Nanashima A, Kinoshita N, Nakanuma Y, Zen Y, Sumida Y, Abo T, Hidaka S, Takeshita H, Yasutake T, Hayashi T, Nagayasu T: Clinicopathological features of "intraductal papillary neoplasm of the bile duct" and patient outcome after surgical resection. Hepatogastroenterology; 2008 Jul-Aug;55(85):1167-73
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  • Five patients had histories of hepatobiliary disease.
  • Tumor markers were not valuable for diagnosis.
  • Five cases were well-differentiated adenocarcinoma and 1 had poorly differentiated adenocarcinoma.
  • In-situ spread of carcinoma was seen along biliary mucosa in 3 cases.
  • [MeSH-minor] Aged. Cohort Studies. Disease-Free Survival. Female. Hepatectomy. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 18795651.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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7. Yu KJ, Rader JS, Borecki I, Zhang Z, Hildesheim A: CD83 polymorphisms and cervical cancer risk. Gynecol Oncol; 2009 Aug;114(2):319-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We sought to replicate a recent study which reported an association between specific SNPs on CD83 and cervical cancer and to further explore whether effects varied by age, clinical stage (in situ versus invasive), and histology (squamous carcinomas versus adenocarcinomas).
  • We also pooled data from the Eastern U.S. (263 cases) with those from the original report (377 cases) to assess the effects of CD83 on the age at diagnosis, disease stage, and histology.
  • RESULTS: Consistent with the original report, carriers of the CT or CC genotypes for one of the five CD83 SNPs evaluated (rs750749) demonstrated a 30% and 50% reduction in disease risk, relative to carriers of the more common TT genotype (p-trend=0.02).
  • Pooled evaluation of cases from the two aforementioned studies suggested differences in the distribution of susceptibility alleles by histology; adenocarcinoma cases were more likely to be carriers of the susceptibility alleles for SNP rs9370729 (p-trend=0.02) and SNP rs750749 (p-trend=0.09).
  • No differences were observed in the age or stage of diagnosis of carriers for CD83 susceptibility alleles relative to non-carriers.
  • CONCLUSIONS: We confirm an association between CD83 polymorphisms and cervical cancer and suggest the possibility that CD83-disease associations might be heterogenous by tumor histology.

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  • [Cites] Cancer Epidemiol Biomarkers Prev. 1999 Dec;8(12):1079-85 [10613340.001]
  • [Cites] Cancer Res. 2007 Dec 1;67(23):11202-8 [18056445.001]
  • [Cites] J Natl Cancer Inst. 2001 Aug 15;93(16):1215-23 [11504767.001]
  • [Cites] Am J Hum Genet. 2002 Feb;70(2):425-34 [11791212.001]
  • [Cites] J Immunol. 2002 Mar 15;168(6):2599-602 [11884422.001]
  • [Cites] Virus Res. 2002 Nov;89(2):229-40 [12445662.001]
  • [Cites] Am J Obstet Gynecol. 2003 Mar;188(3):657-63 [12634637.001]
  • [Cites] Cancer Res. 2003 Nov 1;63(21):7215-20 [14612516.001]
  • [Cites] J Clin Microbiol. 2003 Dec;41(12):5563-71 [14662941.001]
  • [Cites] J Exp Med. 2004 Aug 2;200(3):345-51 [15289503.001]
  • [Cites] Cancer. 1982 Jul 15;50(2):360-3 [7083143.001]
  • [Cites] West J Med. 1983 Sep;139(3):351-9 [6356610.001]
  • [Cites] Mol Biol Evol. 1995 Sep;12(5):921-7 [7476138.001]
  • [Cites] N Engl J Med. 1997 Nov 6;337(19):1343-9 [9358128.001]
  • [Cites] J Natl Cancer Inst. 1999 Feb 3;91(3):226-36 [10037100.001]
  • [Cites] Bioinformatics. 2005 Jan 15;21(2):263-5 [15297300.001]
  • [Cites] Br J Cancer. 2006 Jan 16;94(1):171-5 [16404371.001]
  • [Cites] Cancer Res. 2006 Nov 15;66(22):11070-6 [17108147.001]
  • [Cites] PLoS One. 2007;2(8):e755 [17710154.001]
  • [Cites] J Exp Med. 2007 Nov 26;204(12):3027-36 [18025129.001]
  • [Cites] Trends Immunol. 2008 Apr;29(4):186-94 [18329338.001]
  • [Cites] Cancer Causes Control. 2001 Feb;12(2):153-61 [11246844.001]
  • (PMID = 19446866.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA95713; United States / Intramural NIH HHS / / Z01 CP010158-07; United States / NCI NIH HHS / CA / R01 CA094141; United States / NCI NIH HHS / CA / CA94141; United States / NCI NIH HHS / CA / R01 CA095713
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Membrane Glycoproteins; EC 3.2.2.5 / Antigens, CD38; EC 3.2.2.5 / CD38 protein, human
  • [Other-IDs] NLM/ NIHMS141168; NLM/ PMC2754395
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8. Eisenkop SM, Spirtos NM, Lin WM, Felix J: Laparoscopic modified radical hysterectomy: a strategy for a clinical dilemma. Gynecol Oncol; 2005 Feb;96(2):484-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Between 1996 and 2004, 50 patients with cervical intraepithelial neoplasia (CIN III) or adenocarcinoma in situ (AIS) involvement of cone endocervical margins and/or endocervical curettings, who were not candidates for observation or repeat conization, underwent laparoscopy to perform a modified radical hysterectomy.
  • Of the overall group, 35 (70.0%) had residual pathology; 26 (52.0%) were precancerous lesions, and 9 (18.0%) had invasive disease (5 adenocarcinomas, 3 squamous lesions, and 1 adenosquamous carcinoma).
  • Of the nine with cancer, one had stage IA1 disease, three had stage IA2 disease, and five had stage IB1 disease.
  • All patients with cancer remain disease-free (median follow-up 44.2 months, range 1-88.7 months).
  • [MeSH-major] Cervical Intraepithelial Neoplasia / surgery. Hysterectomy / methods. Uterine Cervical Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / surgery. Adult. Aged. Aged, 80 and over. Carcinoma in Situ / surgery. Female. Humans. Laparoscopy / methods. Middle Aged

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  • (PMID = 15661239.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Reid-Nicholson MD, Ramalingam P, Adeagbo B, Cheng N, Peiper SC, Terris MK: The use of Urovysion fluorescence in situ hybridization in the diagnosis and surveillance of non-urothelial carcinoma of the bladder. Mod Pathol; 2009 Jan;22(1):119-27
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  • [Title] The use of Urovysion fluorescence in situ hybridization in the diagnosis and surveillance of non-urothelial carcinoma of the bladder.
  • Urovysion fluorescence in situ hybridization (FISH) is a sensitive and specific test used to diagnose urothelial carcinoma in urine.
  • We evaluated Urovysion FISH in non-urothelial carcinoma involving bladder to determine its possible application to their diagnosis and surveillance.
  • Cases included 15 primary squamous carcinoma, 2 urothelial carcinoma with squamous differentiation, 4 primary adenocarcinoma, 5 colonic, 4 prostatic and 1 cervical adenocarcinoma.
  • Total 60% of squamous, 83% of pure urothelial, 100% of urothelial carcinoma with squamous differentiation and 100% of primary and secondary adenocarcinomas hybridized successfully; 2/10 (11%) squamous carcinomas and 11/14 (79%) primary and secondary adenocarcinomas were Urovysion FISH-positive with primary adenocarcinomas accounting for 75% (3/4), colonic, 80% (4/5), prostatic, 75% (3/4) and cervical, 100% (1/1) positivity.
  • These false-positive results were frequent in primary and secondary adenocarcinoma and rare in squamous carcinoma.
  • This has significant implications for the accurate diagnosis and management of patients with urinary tract cancer.
  • Urovysion FISH cannot be used to definitively diagnose squamous carcinoma or adenocarcinoma nor can it be used to differentiate the two from urothelial carcinoma.
  • However, it may be useful as a surveillance tool in established primary and secondary bladder adenocarcinoma.
  • [MeSH-major] In Situ Hybridization, Fluorescence / methods. Urinary Bladder Neoplasms / diagnosis. Urinary Bladder Neoplasms / genetics

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  • (PMID = 18978733.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Altinoğlu EI, Russin TJ, Kaiser JM, Barth BM, Eklund PC, Kester M, Adair JH: Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer. ACS Nano; 2008 Oct 28;2(10):2075-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Early detection is a crucial element for the timely diagnosis and successful treatment of all human cancers but is limited by the sensitivity of current imaging methodologies.
  • PEGylated ICG-CPNPs accumulate in solid, 5 mm diameter xenograft breast adenocarcinoma tumors via enhanced retention and permeability (EPR) within 24 h after systemic tail vein injection in a nude mouse model.
  • Ex situ tissue imaging further verifies the facility of the ICG-CPNPs for deep-tissue imaging with NIR signals detectable from depths up to 3 cm in porcine muscle tissue.

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  • [CommentIn] ACS Nano. 2008 Oct 28;2(10):1984-6 [19206441.001]
  • (PMID = 19206454.001).
  • [ISSN] 1936-086X
  • [Journal-full-title] ACS nano
  • [ISO-abbreviation] ACS Nano
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium Phosphates; 0 / Drug Carriers; 97Z1WI3NDX / calcium phosphate; IX6J1063HV / Indocyanine Green
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11. Carter RR, Woodall CE 3rd, McNally ME, Talboy GE, Lankachandra KM, Van Way CW 3rd: Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. Am Surg; 2008 Apr;74(4):338-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors.
  • This report is a case of a 58-year-old woman with a mixed ductal-endocrine carcinoma of the pancreas and a synchronous carcinoma-in-situ of the common bile duct.
  • Biopsies from this lesion showed adenocarcinoma.
  • Subsequently, pancreatoduodenectomy was performed for the diagnosis of peri-ampullary carcinoma.
  • On histopathological examination, it was discovered that this lesion contained two separate neoplasms: papillary carcinoma-in-situ of the intraparenchymal portion of the common bile duct and a mixed ductal-endocrine carcinoma of the pancreas.
  • Finding it in conjunction with a synchronous, overlying papillary carcinoma carcinoma-in-situ of the common bile duct has not been previously described.
  • [MeSH-major] Carcinoma in Situ / pathology. Carcinoma, Pancreatic Ductal / pathology. Common Bile Duct Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Pancreatic Neoplasms / pathology


12. van der Aa MA, Helmerhorst TJ, Siesling S, Riemersma S, Coebergh JW: Vaginal and (uncommon) cervical cancers in the Netherlands, 1989-2003. Int J Gynecol Cancer; 2010 May;20(4):638-45
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The clinical and prognostic evaluation of cervical and vaginal tumors other than squamous cell and adenocarcinomas is hampered by the low incidence, and clinical and epidemiological studies on these uncommon tumors are scarce.
  • Having close affinity with the pathology laboratories, the Netherlands Cancer Registry offers a great opportunity to study frequency, stage, treatment, and survival of uncommon tumors in the cervix and vagina and separately, the clear cell adenocarcinoma of the vagina and cervix.
  • METHODS: All invasive cervical tumors (n = 10,570) and all in situ and invasive vaginal tumors (n = 778) diagnosed in the Netherlands during 1989-2003 were selected from the Netherlands Cancer Registry.
  • Age, stage at diagnosis, and treatment were described for each histological subgroup to find differences between common and uncommon tumors, including 5-year relative survival rates.
  • Patients with clear cell adenocarcinoma of the vagina and cervix were found across all age categories.
  • CONCLUSIONS: The less common histological types of cervical and vaginal cancers were clearly different from squamous cell carcinomas, especially with respect to age at diagnosis and survival rates.
  • [MeSH-major] Adenocarcinoma / mortality. Carcinoma, Squamous Cell / mortality. Neoplasms, Glandular and Epithelial / mortality. Uterine Cervical Neoplasms / mortality. Vaginal Neoplasms / mortality


13. Sobczuk A, Wrona M, Pertyński T: [New views on hyperplastic endometrial lesions classification--endometrial intraepithelial neoplasia (EIN)]. Ginekol Pol; 2007 Dec;78(12):986-9
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  • [Title] [New views on hyperplastic endometrial lesions classification--endometrial intraepithelial neoplasia (EIN)].
  • The diagnosis of precancerous disease of the endometrium remains non-standardized because the most widely used World Health Organisation classification is a poorly reproducible system, which does not specify objective architectural criteria for each category of hyperplasia and does not correspond to an appropriate clinical management (undertreatment, overtreatment of the lesions).
  • The new proposed EIN diagnostic schema, based on integrated morphological, genetic molecular, objective histomorphometric (D-score) and clinical outcome studies, divides endometrial lesions into three categories: benign hyperplasia, endometrial intraepithelial neoplasia, and cancer.
  • [MeSH-major] Adenocarcinoma / classification. Carcinoma in Situ / classification. Endometrial Hyperplasia / classification. Endometrial Neoplasms / classification. Precancerous Conditions / classification

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  • (PMID = 18411925.001).
  • [ISSN] 0017-0011
  • [Journal-full-title] Ginekologia polska
  • [ISO-abbreviation] Ginekol. Pol.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 36
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14. Gunnell AS, Ylitalo N, Sandin S, Sparén P, Adami HO, Ripatti S: A longitudinal Swedish study on screening for squamous cell carcinoma and adenocarcinoma: evidence of effectiveness and overtreatment. Cancer Epidemiol Biomarkers Prev; 2007 Dec;16(12):2641-8
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  • [Title] A longitudinal Swedish study on screening for squamous cell carcinoma and adenocarcinoma: evidence of effectiveness and overtreatment.
  • However, the potential for overtreatment of precursor lesions is quite high for SCC, and the effectiveness of Pap screening for prevention of cervical adenocarcinoma is questionable.
  • METHODS: Using the nationwide, virtually complete Swedish Cancer Register, we analyzed standardized incidence rates for SCC in situ (CIS), SCC, adenocarcinoma in situ (AIS) and adenocarcinoma, between 1968 and 2002.
  • For each county, we calculated Spearman correlations between incidence of in situ lesions and incidence of invasive cancer, 5, 10, and 15 years later.
  • We also used generalized estimating equation (GEE) models to compare adjusted estimates for associations between in situ incidences and invasive carcinomas over counties.
  • A similar benefit was not apparent for adenocarcinoma.
  • For adenocarcinoma and AIS, similar analyses gave corresponding estimates of 1.17 for the 5-year and 1.08 for the 10-year lag periods.
  • CONCLUSION: Our data confirm the effectiveness of Pap smear screening in reducing the incidence of SCC, but suggest no clear benefit on adenocarcinoma.
  • Our data also suggest that relaxed histopathologic criteria for diagnosis of cervical CIS may increase its recorded incidence with no measurable benefit in the reduction of invasive cancer.
  • [MeSH-major] Adenocarcinoma / epidemiology. Carcinoma in Situ / epidemiology. Carcinoma, Squamous Cell / epidemiology. Papanicolaou Test. Uterine Cervical Neoplasms / epidemiology. Vaginal Smears


15. Shinozaki A, Ushiku T, Fukayama M: Prominent Mott cell proliferation in Epstein-Barr virus-associated gastric carcinoma. Hum Pathol; 2010 Jan;41(1):134-8
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  • In situ hybridization for Epstein-Barr virus (EBV)-encoded small RNA (EBER) labeled the carcinoma cells but not the lymphoplasmacytic cells.
  • The differential diagnosis included primary gastric lymphoma and nonneoplastic conditions such as Russell body gastritis; EBER in situ hybridization was helpful in their differentiation.
  • [MeSH-major] Adenocarcinoma / diagnosis. Epstein-Barr Virus Infections / pathology. Herpesvirus 4, Human / isolation & purification. Plasma Cells / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Gastrectomy. Gastritis / diagnosis. Humans. In Situ Hybridization. Inclusion Bodies / pathology. Lymphoma / diagnosis. Male. Neoplasm Staging. RNA, Viral / analysis. RNA-Binding Proteins / metabolism. Ribosomal Proteins / metabolism. Treatment Outcome

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  • (PMID = 19665167.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Viral; 0 / RNA-Binding Proteins; 0 / Ribosomal Proteins; 135844-68-7 / RPL22 protein, human
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16. Meyer-Siegler KL, Iczkowski KA, Vera PL: Further evidence for increased macrophage migration inhibitory factor expression in prostate cancer. BMC Cancer; 2005;5:73
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  • Additional aims were to examine MIF expression, as well as the location of MIF's receptor, CD74, in human prostatic adenocarcinoma compared to matched benign prostate.
  • Prostate tissue arrays were processed for MIF in situ hybridization and immunohistochemistry for MIF and CD74.
  • RESULTS: Median serum MIF amounts were significantly elevated in prostate cancer patients (5.87 +/- 3.91 ng/ml; +/- interquartile range; n = 115) compared with patients with no documented diagnosis of prostate cancer (2.19 +/- 2.65 ng/ml; n = 158).
  • Increased MIF mRNA expression was observed in prostatic adenocarcinoma compared to benign tissue from matched samples, supporting our earlier finding of increased MIF gene expression in prostate cancer.
  • [MeSH-minor] Adenocarcinoma / metabolism. Antigens, Differentiation, B-Lymphocyte / biosynthesis. Blotting, Western. Cell Line, Tumor. Enzyme-Linked Immunosorbent Assay. Epithelium / metabolism. Histocompatibility Antigens Class II / biosynthesis. Humans. Immunohistochemistry. Immunoprecipitation. In Situ Hybridization. Male. Prostate / metabolism. Prostate-Specific Antigen / blood. RNA, Messenger / metabolism. Serum Albumin, Bovine / metabolism

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  • [Cites] J Exp Med. 2003 Jun 2;197(11):1467-76 [12782713.001]
  • [Cites] Carcinogenesis. 2002 Jun;23(6):967-75 [12082018.001]
  • [Cites] J Cell Biochem. 2004 Feb 15;91(3):459-77 [14755677.001]
  • [Cites] Biophys Chem. 2004 Mar 1;108(1-3):77-87 [15043922.001]
  • [Cites] J Urol. 2004 Jun;171(6 Pt 1):2234-8 [15126793.001]
  • [Cites] BMC Cancer. 2004 Jul 12;4:34 [15248897.001]
  • [Cites] Science. 1966 Jul 1;153(3731):80-2 [5938421.001]
  • [Cites] Proc Natl Acad Sci U S A. 1966 Jul;56(1):72-7 [5229858.001]
  • [Cites] J Biol Chem. 1990 Apr 5;265(10):5787-92 [1690714.001]
  • [Cites] Biol Chem Hoppe Seyler. 1994 Jun;375(6):393-9 [7980871.001]
  • [Cites] J Biol Chem. 1995 Oct 13;270(41):24598-603 [7592680.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 May 28;93(11):5191-6 [8643551.001]
  • [Cites] Urology. 1996 Sep;48(3):448-52 [8804500.001]
  • [Cites] Adv Immunol. 1997;66:197-223 [9328642.001]
  • [Cites] Electrophoresis. 1997 Dec;18(15):2832-41 [9504817.001]
  • [Cites] Diagn Mol Pathol. 1998 Feb;7(1):44-50 [9646034.001]
  • [Cites] Semin Cancer Biol. 1999 Apr;9(2):83-93 [10202130.001]
  • [Cites] Prostate. 1999 May 15;39(3):159-65 [10334104.001]
  • [Cites] Mol Med. 1999 Mar;5(3):181-91 [10404515.001]
  • [Cites] Prostate. 2005 Jan 1;62(1):34-9 [15389818.001]
  • [Cites] J Urol. 2005 Feb;173(2):615-20 [15643275.001]
  • [Cites] Oncol Rep. 2005 May;13(5):983-8 [15809768.001]
  • [Cites] J Urol. 2005 Jul;174(1):338-43 [15947686.001]
  • [Cites] Immunology. 1999 Oct;98(2):296-302 [10540230.001]
  • [Cites] Ann Clin Biochem. 1999 Nov;36 ( Pt 6):704-21 [10586307.001]
  • [Cites] Anticancer Res. 1999 Jul-Aug;19(4B):3315-20 [10652627.001]
  • [Cites] J Biol Chem. 2000 Feb 25;275(8):5826-31 [10681572.001]
  • [Cites] J Urol. 2000 Jun;163(6):1739-42 [10799172.001]
  • [Cites] Cancer. 2000 Jul 15;89(2):334-41 [10918163.001]
  • [Cites] Prostate. 2000 Sep 15;45(1):51-7 [10960842.001]
  • [Cites] J Interferon Cytokine Res. 2000 Sep;20(9):751-62 [11032394.001]
  • [Cites] J Interferon Cytokine Res. 2000 Sep;20(9):769-78 [11032396.001]
  • [Cites] J Biol Chem. 2001 Dec 7;276(49):46212-8 [11583997.001]
  • [Cites] Crit Care Med. 2002 Jan;30(1 Suppl):S27-35 [11782558.001]
  • [Cites] Cancer. 2002 Mar 1;94(5):1449-56 [11920501.001]
  • [Cites] J Biol Chem. 2003 Aug 15;278(33):30889-95 [12740374.001]
  • (PMID = 16000172.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Differentiation, B-Lymphocyte; 0 / Histocompatibility Antigens Class II; 0 / Macrophage Migration-Inhibitory Factors; 0 / RNA, Messenger; 0 / Serum Albumin, Bovine; 0 / invariant chain; EC 3.4.21.77 / Prostate-Specific Antigen
  • [Other-IDs] NLM/ PMC1177932
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17. Stelow EB, Adams RB, Moskaluk CA: The prevalence of pancreatic intraepithelial neoplasia in pancreata with uncommon types of primary neoplasms. Am J Surg Pathol; 2006 Jan;30(1):36-41
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  • [Title] The prevalence of pancreatic intraepithelial neoplasia in pancreata with uncommon types of primary neoplasms.
  • Pancreatic ductal adenocarcinoma is thought to develop through a series of genetic events through its purported precursor lesion, pancreatic intraepithelial neoplasia (PanIN).
  • All pancreata resected at the University of Virginia from June 1, 1991 to March 1, 2005 for neoplasia not diagnosed as conventional ductal adenocarcinoma were reviewed and classified according to the World Health Organization's classification schema for tumors of the exocrine and endocrine pancreas.
  • Although the high prevalence of PanIN in pancreata concomitantly harboring certain uncommon neoplasms of the pancreas could signify its role as a precursor lesion for those neoplasms, its high prevalence throughout our series may simply be the result of a coincidental, prevalent finding seen in all pancreata, especially with aging.
  • Because of the ubiquitous nature of PanIN, it should not be used histologically to assist in the diagnosis and subclassification of pancreatic neoplasia.
  • [MeSH-major] Carcinoma in Situ / pathology. Carcinoma, Pancreatic Ductal / pathology. Pancreatic Neoplasms / pathology. Precancerous Conditions / pathology
  • [MeSH-minor] Age Factors. Aged. Cystadenocarcinoma, Mucinous / pathology. Cystadenocarcinoma, Serous / pathology. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Prevalence

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  • (PMID = 16330940.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Uzan C, Andre F, Scott V, Laurent I, Azria E, Suciu V, Balleyguier C, Lacroix L, Delaloge S, Vielh P: Fine-needle aspiration for nucleic acid-ased molecular analyses in breast cancer. Cancer; 2009 Feb 25;117(1):32-9
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  • For malignant lesions, the authors attempted to correlate estrogen receptor 1 (ESR1) and HER-2 (c-erb-B2) mRNA expression measured by real-time quantitative polymerase chain reaction with estrogen receptor and HER-2 detection obtained by immunohistochemistry (IHC) and/or fluorescent in situ hybridization (FISH) on the surgical specimen.
  • RESULTS: The amount of mRNA obtained was >1 microg in 89.5% of 124 samples (43 benign lesions and 81 adenocarcinomas).
  • The most significant predictors of quality and quantity of mRNA were the cytopathologist who sampled the tumors and a diagnosis of cancer versus benign lesion.
  • [MeSH-major] Adenocarcinoma / diagnosis. Biopsy, Fine-Needle. Breast Neoplasms / diagnosis. RNA, Messenger / isolation & purification
  • [MeSH-minor] Estrogen Receptor alpha / biosynthesis. Estrogen Receptor alpha / genetics. Female. Gene Expression Profiling. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Middle Aged. Receptor, ErbB-2 / biosynthesis. Receptor, ErbB-2 / genetics. Reverse Transcriptase Polymerase Chain Reaction

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  • [Copyright] (c) 2009 American Cancer Society.
  • (PMID = 19347827.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Estrogen Receptor alpha; 0 / RNA, Messenger; EC 2.7.10.1 / Receptor, ErbB-2
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19. Miyashita M, Agdamag DM, Sasagawa T, Matsushita K, Salud LM, Salud CO, Saikawa K, Leano PS, Pagcaliwagan T, Acuna J, Ishizaki A, Kageyama S, Ichimura H: High-risk HPV types in lesions of the uterine cervix of female commercial sex workers in the Philippines. J Med Virol; 2009 Mar;81(3):545-51
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  • Among 56 women with abnormal cervical cytology (low- and high-grade squamous intraepithelial lesions and adenocarcinoma in situ), HPV-52 was most common (23.2%), followed by HPV-16 (19.6%), -58 (10.7%), and -67 (10.7%).

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  • [Copyright] Copyright 2009 Wiley-Liss, Inc.
  • (PMID = 19152419.001).
  • [ISSN] 1096-9071
  • [Journal-full-title] Journal of medical virology
  • [ISO-abbreviation] J. Med. Virol.
  • [Language] eng
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  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral
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20. Wang RA, Zhang H, Balasenthil S, Medina D, Kumar R: PAK1 hyperactivation is sufficient for mammary gland tumor formation. Oncogene; 2006 May 11;25(20):2931-6
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  • Finally, we found that consistent with a role in breast tumor progression, Pak1 expression and its nuclear accumulation was increased progressively during the transition from ductal hyperplasia to ductal carcinoma in situ to adenocarcinoma in widely used multistep polyoma-middle T-antigen transgenic mice.
  • [MeSH-minor] Animals. Antigens, Polyomavirus Transforming / physiology. Disease Models, Animal. Disease Progression. Enzyme Activation. Estrogen Receptor alpha / metabolism. Humans. MAP Kinase Kinase 1 / metabolism. MAP Kinase Kinase 2 / metabolism. Mammary Glands, Animal / enzymology. Mammary Glands, Animal / pathology. Mice. Mice, Inbred C57BL. Mice, Inbred DBA. Mice, Transgenic. Receptors, Progesterone / metabolism. Up-Regulation. p21-Activated Kinases. p38 Mitogen-Activated Protein Kinases / metabolism

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  • (PMID = 16331248.001).
  • [ISSN] 0950-9232
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 65746; United States / NCI NIH HHS / CA / CA 90970
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Polyomavirus Transforming; 0 / Estrogen Receptor alpha; 0 / Pak1 protein, mouse; 0 / Receptors, Progesterone; EC 2.7.1.- / Map2k1 protein, mouse; EC 2.7.1.- / Map2k2 protein, mouse; EC 2.7.11.1 / PAK1 protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / p21-Activated Kinases; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases; EC 2.7.12.2 / MAP Kinase Kinase 1; EC 2.7.12.2 / MAP Kinase Kinase 2
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21. Pascual JC, Perez-Ramos M, Devesa JP, Kutzner H, Requena L: Extramammary Paget's disease of the groin with underlying carcinoma and fatal outcome. Clin Exp Dermatol; 2008 Aug;33(5):595-8
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  • [Title] Extramammary Paget's disease of the groin with underlying carcinoma and fatal outcome.
  • Extramammary Paget's disease (EMPD) is considered to be an intraepithelial adenocarcinoma.
  • An unusual feature of EMPD is its association with cutaneous, adnexal-structure adenocarcinomas and its association with internal malignancies.
  • Cutaneous EMPD is characteristically positive for cytokeratin (CK)7, negative for CK20, and positive for gross cystic disease fluid protein (GCDFP)15+, whereas endodermal EMPD shows a CK7+ CK20+ GCDFP15- phenotype.
  • [MeSH-major] Genital Neoplasms, Male / pathology. Paget Disease, Extramammary / pathology. Scrotum / pathology


22. Song X, Song Z, Lv Y, Zhong M, Li X: [The Study on Gene Amplification of EGFR in Bronchioloalveolar Carcinoma and Conventional Adenocarcinoma of the Lung.]. Zhongguo Fei Ai Za Zhi; 2009 Aug 20;12(8):879-83
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  • [Title] [The Study on Gene Amplification of EGFR in Bronchioloalveolar Carcinoma and Conventional Adenocarcinoma of the Lung.].
  • BACKGROUND: Patients with adenocarcinoma of the lung have disproportionately response to the epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).
  • The aim of this study is to analyze the difference of EGFR gene amplification in bronchioloalveolar carcinoma (BAC), adenocarcinma mixed subtype and conventional adenocarcinoma of the lung and provide some information to clinical therapies.
  • The definite diagnosis of BAC based on 2004 WHO classification of lung tumors was made by two pathologists.
  • Fluorescence in situ hybridization (FISH) was performed to detect EGFR gene amplification in pure BAC, adenocarcinma mixed subtype and conventional adenocarcinoma.
  • RESULTS: Conventional adenocarcinoma had higher EGFR amplification compared with pure BAC and adenocarcinma mixed subtype (Chi-square=11.632, P<0.05).
  • EGFR gene amplification was found in 45.45% of conventional adenocarcinoma, 14.81% in pure BACs, and 22.58% in adenocarcinma mixed subtype.
  • EGFR gene amplification might be associated with the development of adenocarcinoma of the lung.

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  • (PMID = 20719175.001).
  • [ISSN] 1999-6187
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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23. Antoine M: [Contribution of immunohistochemistry to the management of lung cancer: from morphology to diagnosis and treatment]. Rev Pneumol Clin; 2007 Jun;63(3):183-92
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  • [Title] [Contribution of immunohistochemistry to the management of lung cancer: from morphology to diagnosis and treatment].
  • Using IHC techniques, pathologists can now determine with certainty that an intrathoracic adenocarcinoma is primary or secondary.
  • Other morphological techniques such as hybridization in situ or molecular biology techniques will further complete the histological diagnosis in the future.
  • [MeSH-minor] Adenocarcinoma / pathology. Biomarkers, Tumor / analysis. Carcinoma, Large Cell / pathology. Carcinoma, Small Cell / pathology. Carcinoma, Squamous Cell / pathology. Carcinoma, Transitional Cell / pathology. Chorionic Gonadotropin, beta Subunit, Human / analysis. Forecasting. Humans. Lymph Nodes / pathology. Lymphoma / pathology. Mediastinal Neoplasms / pathology. Melanoma / pathology. Neoplasm Staging. Neuroendocrine Tumors / pathology. Pleural Neoplasms / pathology. Prognosis. Sarcoma / pathology. alpha-Fetoproteins / analysis

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  • (PMID = 17675942.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chorionic Gonadotropin, beta Subunit, Human; 0 / alpha-Fetoproteins
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24. Zhao CH, Li QF: Altered profiles of nuclear matrix proteins during the differentiation of human gastric mucous adenocarcinoma MGc80-3 cells. World J Gastroenterol; 2005 Aug 14;11(30):4628-33
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  • [Title] Altered profiles of nuclear matrix proteins during the differentiation of human gastric mucous adenocarcinoma MGc80-3 cells.
  • AIM: To find and identify specific nuclear matrix proteins associated with proliferation and differentiation of carcinoma cells, which will be potential markers for cancer diagnosis and targets in cancer therapy.
  • Spots of nuclear matrix proteins differentially expressed were excised and subjected to in situ digestion with trypsin.
  • [MeSH-major] Adenocarcinoma, Mucinous / metabolism. Neoplasm Proteins / metabolism. Nuclear Matrix-Associated Proteins / metabolism. Stomach Neoplasms / metabolism

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  • (PMID = 16094700.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / Nuclear Matrix-Associated Proteins
  • [Other-IDs] NLM/ PMC4615401
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25. Hermsen M, Snijders A, Guervós MA, Taenzer S, Koerner U, Baak J, Pinkel D, Albertson D, van Diest P, Meijer G, Schrock E: Centromeric chromosomal translocations show tissue-specific differences between squamous cell carcinomas and adenocarcinomas. Oncogene; 2005 Feb 24;24(9):1571-9
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  • [Title] Centromeric chromosomal translocations show tissue-specific differences between squamous cell carcinomas and adenocarcinomas.
  • Here, we compared the location of centromeric breaks associated with whole arm translocations in seven adenocarcinoma cell lines and nine squamous cell carcinoma cell lines using SKY, microarray-based comparative genomic hybridization (array CGH) and fluorescence in situ hybridization (FISH).
  • Whole arm translocations were more frequent in squamous cell carcinomas (112 in nine cell lines and nine in one short-term culture) than in adenocarcinomas (13 in seven cases) and most often resulted in copy number alterations.
  • Array CGH analysis demonstrated that in all squamous cell carcinomas and in most adenocarcinomas, the breakpoints of unbalanced whole arm translocations occurred between the two clones on the array flanking the centromeres.
  • However, FISH with centromeric probes revealed that in squamous cell carcinomas, the marker chromosomes with whole arm translocations contained centromeres comprised of material from both participating chromosomes, while in adenocarcinomas centromeric material from only one of the chromosomes was present.
  • These observations suggest that different mechanisms of centromeric instability underlie the formation of chromosomal aberrations in adenocarcinomas and squamous cell carcinomas.
  • [MeSH-major] Adenocarcinoma / genetics. Carcinoma, Squamous Cell / genetics. Centromere / genetics. Chromosomes, Human / genetics. Translocation, Genetic
  • [MeSH-minor] Cell Line, Tumor. Chromosome Mapping. Diagnosis, Differential. Humans. In Situ Hybridization, Fluorescence. Karyotyping. Nucleic Acid Hybridization. Oligonucleotide Array Sequence Analysis

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  • (PMID = 15674345.001).
  • [ISSN] 0950-9232
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA94407
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
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26. Modem RR, Otis CN, Florence RR, Pantanowitz L: Intestinal type adenocarcinoma in situ of the cervix. Diagn Cytopathol; 2007 Sep;35(9):584-5
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  • [Title] Intestinal type adenocarcinoma in situ of the cervix.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma in Situ / pathology. Intestinal Neoplasms / pathology. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Cytological Techniques. Diagnosis, Differential. Female. Humans. Vaginal Smears


27. Raspollini MR, Fambrini M, Marchionni M, Baroni G, Taddei GL: In situ adenocarcinoma and squamous carcinoma of uterine cervix. Pathological and immunohistochemical analysis with cytokeratin 13. Eur J Obstet Gynecol Reprod Biol; 2007 Oct;134(2):249-53
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  • [Title] In situ adenocarcinoma and squamous carcinoma of uterine cervix. Pathological and immunohistochemical analysis with cytokeratin 13.
  • OBJECTIVES: The aim of the study was the pathological and immunohistochemical analysis of cytokeratin 13 (CK13) in intraepithelial cervical tumors.
  • STUDY DESIGN: We studied 415 in situ squamous carcinomas and 13 in situ mucinous cervical type adenocarcinomas of the uterine cervix.
  • RESULTS: 3% of the squamous carcinoma patients recurred during the follow-up period, while the percentage of recurrence of in situ adenocarcinoma patients was 7.6%.
  • The percentage of recurrence was high among the cases with positive borders independently from their histopathologic type (14.3% in the squamous carcinomas versus 50% in the adenocarcinomas), compared to cases with negative edges (2.3% in the squamous carcinomas versus 0% in the adenocarcinomas).
  • We observed CK13 positive staining in cervical squamous tumors and in mucinous cervical type adenocarcinomas, while there was no positive staining in non-neoplastic cervical glandular elements.
  • CONCLUSION: CK13 positive immunostaining among in situ squamous and in situ mucinous cervical type adenocarcinoma cases adds additional evidence to data supporting a common origin of the two lesions.
  • [MeSH-major] Adenocarcinoma, Mucinous / metabolism. Carcinoma in Situ / metabolism. Carcinoma, Squamous Cell / metabolism. Keratin-13 / metabolism. Uterine Cervical Neoplasms / metabolism

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  • (PMID = 16949723.001).
  • [ISSN] 0301-2115
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Keratin-13
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28. Kietpeerakool C, Srisomboon J, Khunamornpong S, Siriaunkgul S, Sukkawattananon W: How can the overtreatment rate of "see and treat" approach be reduced in women with high-grade squamous intraepithelial lesion on cervical cytology? Asian Pac J Cancer Prev; 2007 Apr-Jun;8(2):206-8
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  • [Title] How can the overtreatment rate of "see and treat" approach be reduced in women with high-grade squamous intraepithelial lesion on cervical cytology?
  • BACKGROUND: The aim of this study was to determine the incidence and predictors of overtreatment in "see and treat" approach using loop electrosurgical excision procedure (LEEP) in women with high-grade squamous intraepithelial lesion (HSIL) on cervical cytology.
  • Of 446 women, histologically-confirmed HSIL, invasive cancer, low-grade squamous intraepithelial lesions, and adenocarcinoma in situ were detected in 330 (74.0%), 76 (17.0%), 9 (2.0%), and 5 (1.1%), respectively.

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  • (PMID = 17696732.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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29. Schmid RM: [Pancreatic cancer]. Praxis (Bern 1994); 2006 Nov 1;95(44):1709-12
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  • The most common cancer in the pancreas is ductal adenocarcinoma.
  • The precursor lesions are called pancreatic intraepithelial neoplasia.
  • Multidetector CT incorporating dual-phase imaging in the arterial and venous phases of enhancement is the preferred imaging modality for the diagnosis and staging of pancreatic cancer.
  • Gemcitabine is still the standard for unresectable locally advanced disease or distant metastasis.
  • [MeSH-major] Carcinoma, Pancreatic Ductal / diagnosis. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Carcinoma in Situ / diagnosis. Carcinoma in Situ / pathology. Carcinoma in Situ / surgery. Cyclin-Dependent Kinase Inhibitor p16 / genetics. Deoxycytidine / analogs & derivatives. Deoxycytidine / therapeutic use. Gene Expression Regulation, Neoplastic / genetics. Genes, ras / genetics. Humans. Palliative Care. Pancreas / pathology. Pancreatectomy. Prognosis. Smad4 Protein / genetics. Tomography, X-Ray Computed. Tumor Suppressor Protein p53 / genetics

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  • (PMID = 17111879.001).
  • [ISSN] 1661-8157
  • [Journal-full-title] Praxis
  • [ISO-abbreviation] Praxis (Bern 1994)
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / SMAD4 protein, human; 0 / Smad4 Protein; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
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30. Michaels PJ, Brachtel EF, Bounds BC, Brugge WR, Pitman MB: Intraductal papillary mucinous neoplasm of the pancreas: cytologic features predict histologic grade. Cancer; 2006 Jun 25;108(3):163-73
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  • These cytologic features were subsequently correlated with the histologic diagnosis.
  • Necrosis distinguished IPMN with carcinoma from IPMN-adenomas and IPMN with moderate dysplasia (P < .00001), and was more often observed with invasion than IPMN-carcinoma in situ (P < .05).
  • Pale nuclei with parachromatin clearing was found to be a nuclear feature that was suspicious for at least carcinoma in situ (P < .001).
  • In addition, significant background inflammation (neutrophils and histiocytes) was found to be more characteristic of IPMN with at least carcinoma in situ (P = .002).
  • The presence of tight epithelial cell clusters is consistent with a neoplasm of at least moderate dysplasia, and abundant background inflammation and parachromatin clearing correlated with the presence of at least carcinoma in situ.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology. Carcinoma, Papillary / pathology. Mucins / metabolism. Pancreatic Neoplasms / pathology

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  • (PMID = 16550572.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucins
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31. Ho SA, Aw DC: Extramammary Paget's disease treated with topical imiquimod 5% cream. Dermatol Ther; 2010 Jul-Aug;23(4):423-7
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  • [Title] Extramammary Paget's disease treated with topical imiquimod 5% cream.
  • Extramammary Paget's disease (EMPD) is a rare cutaneous, intraepithelial adenocarcinoma usually found in the apocrine gland bearing areas.
  • [MeSH-major] Aminoquinolines / therapeutic use. Antineoplastic Agents / therapeutic use. Paget Disease, Extramammary / drug therapy

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  • (PMID = 20666831.001).
  • [ISSN] 1529-8019
  • [Journal-full-title] Dermatologic therapy
  • [ISO-abbreviation] Dermatol Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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32. Gold DV, Karanjawala Z, Modrak DE, Goldenberg DM, Hruban RH: PAM4-reactive MUC1 is a biomarker for early pancreatic adenocarcinoma. Clin Cancer Res; 2007 Dec 15;13(24):7380-7
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  • [Title] PAM4-reactive MUC1 is a biomarker for early pancreatic adenocarcinoma.
  • PURPOSE: The anti-MUC1 monoclonal antibody (MAb), PAM4, has a high specificity for pancreatic adenocarcinoma compared with other cancers, normal tissues, or pancreatitis.
  • In order to assess its role in early pancreatic cancer development, we examined the expression of the PAM4-reactive MUC1 in the noninvasive precursor lesions, pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasia (IPMN).
  • RESULTS: The PAM4-reactive MUC1 epitope was not detected in normal pancreas but was expressed in 87% (48 of 55) of invasive pancreatic adenocarcinomas, including early stage 1 disease: PAM4 labeled 94% (44 of 47) of the earliest PanIN lesions, PanIN-1A and 1B, along with 91% (10 of 11) of PanIN-2, 40% (2 of 5) of PanIN-3, and 86% (31 of 36) of intraductal papillary mucinous neoplasia lesions.
  • CONCLUSIONS: The results suggest that expression of the PAM4-reactive antigen may represent an early event in the development of invasive pancreatic adenocarcinoma, and is unrelated to the VNTR peptide core epitopes of MUC1.
  • Detection of this biomarker using immunohistology, in vitro immunoassays, and in vivo antibody-based imaging may provide new opportunities for the early detection and improved diagnosis of pancreatic cancer.
  • [MeSH-major] Antibodies, Monoclonal. Biomarkers, Tumor / analysis. Carcinoma in Situ / diagnosis. Carcinoma, Pancreatic Ductal / diagnosis. Mucin-1 / metabolism. Pancreatic Neoplasms / diagnosis

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  • [CommentIn] Clin Cancer Res. 2008 Aug 15;14(16):5306; author reply 5306-7 [18698052.001]
  • (PMID = 18094420.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA096924; United States / NCI NIH HHS / CA / CA62924
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Biomarkers, Tumor; 0 / Epitopes; 0 / Mucin-1
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33. Little L, Stewart CJ: Cyclin D1 immunoreactivity in normal endocervix and diagnostic value in reactive and neoplastic endocervical lesions. Mod Pathol; 2010 Apr;23(4):611-8
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  • It may be difficult to distinguish reactive glandular lesions from adenocarcinoma in situ of the uterine cervix, and although several immunohistochemical markers have established value in this diagnostic setting, none is completely reliable.
  • Therefore, we investigated cyclin D1 staining in a series of 64 cervical biopsy specimens including examples of normal and reactive endocervical epithelium, adenocarcinoma in situ, stratified mucin-producing intraepithelial lesions, and invasive adenocarcinoma.
  • Thirteen specimens also included a component of high-grade cervical squamous intraepithelial neoplasia.
  • In contrast, most cases of adenocarcinoma in situ were completely negative and, therefore, cyclin D1 staining distinguished benign from neoplastic epithelial cells.
  • Although focal cyclin D1 expression was observed in 5/19 cases of adenocarcinoma in situ, the staining was associated with more marked cytological atypia precluding confusion with a reactive process.
  • The invasive adenocarcinomas were mainly negative for cyclin D1.
  • In conclusion, cyclin D1 can be included within an immunohistochemical panel to aid in the distinction between reactive cervical glandular lesions and adenocarcinoma in situ.
  • The localized distribution of staining within invasive lesions suggests that cyclin D1 up-regulation has a specific role during the progression of some endocervical adenocarcinomas.
  • [MeSH-major] Adenocarcinoma / metabolism. Cervical Intraepithelial Neoplasia / metabolism. Cervix Uteri / metabolism. Cyclin D1 / biosynthesis. Uterine Cervical Neoplasms / metabolism

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  • (PMID = 20062011.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 136601-57-5 / Cyclin D1
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34. Tamas EF, Nielsen ME, Schoenberg MP, Epstein JI: Lymphoepithelioma-like carcinoma of the urinary tract: a clinicopathological study of 30 pure and mixed cases. Mod Pathol; 2007 Aug;20(8):828-34
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  • Seventeen cases (56.7%) were pure with the remaining mixed with other patterns of carcinoma, including invasive urothelial carcinoma (n=10), invasive adenocarcinoma (n=3), and squamous cell carcinoma (n=2).
  • The surface demonstrated carcinoma in situ (CIS) in six cases, noninvasive high-grade papillary urothelial carcinoma in three cases, and in situ adenocarcinoma in one case.
  • None of the 26 cases labeled for EBV-encoded RNA by in situ hybridization.
  • Of the three pure cases treated by chemotherapy, two were free of disease at 4 and 65 months and the third had recurrent disease at 17 months.
  • [MeSH-minor] Adenocarcinoma / pathology. Aged. Aged, 80 and over. Carcinoma in Situ / pathology. Carcinoma, Squamous Cell / pathology. Cell Differentiation. Disease-Free Survival. Epithelial Cells / pathology. Female. Follow-Up Studies. Humans. Lymphocytes / pathology. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Time Factors. Treatment Outcome

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  • (PMID = 17541442.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Salvia R, Partelli S, Crippa S, Landoni L, Capelli P, Manfredi R, Bassi C, Pederzoli P: Intraductal papillary mucinous neoplasms of the pancreas with multifocal involvement of branch ducts. Am J Surg; 2009 Nov;198(5):709-14
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  • PATIENTS AND METHODS: Our database of patients affected by IPMN was queried to identify patients with a clinicoradiologic or a pathologic diagnosis of multifocal BD-IPMN between January 1990 and December 2006.
  • RESULTS: One hundred thirty-one patients (52 male and 79 female; median age 67 years) had a clinicoradiologic or a histopathologic diagnosis of multifocal BD-IPMN.
  • One patient with invasive carcinoma developed hepatic metastases and died of disease 88 months after surgery.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma in Situ / pathology. Carcinoma in Situ / surgery. Female. Humans. Male. Middle Aged. Pancreatectomy

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  • (PMID = 19887201.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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36. Buxant F, Noël JC: Pl6 expression in Paget's disease of the breast. Eur J Gynaecol Oncol; 2008;29(5):441-3
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  • [Title] Pl6 expression in Paget's disease of the breast.
  • BACKGROUND: Paget's disease of the nipple is generally associated with an underlying invasive cancer or an underlying ductal carcinoma in situ.
  • Epidermotropic theory maintains that Paget's cells are derived from an underlying mammary in situ adenocarcinoma.
  • Because p16 protein plays a major role in cell-cycle control and in tumoral cell mobility, we analyzed p16 expression in Paget's disease of the nipple and in associated underlying ductal carcinoma in situ.
  • METHODS: The expression of p16 protein was analyzed by immunohistochemistry in eight cases of Paget's disease of the nipple with associated underlying ductal carcinoma in situ.
  • RESULTS: The expression of p16 protein was observed in 87.5% (7/8 cases) both in the nipple disease and in the associated underlying ductal carcinoma in situ.
  • CONCLUSION: The positive p16 expression in Paget's disease of the nipple and the underlined ductal carcinoma in situ and its role in cell motility lead us to propose a role of p16 in the spread of this disease.
  • [MeSH-major] Neoplasm Proteins / analysis. Paget's Disease, Mammary / chemistry
  • [MeSH-minor] Carcinoma in Situ / chemistry. Carcinoma, Ductal / chemistry. Female. Humans. Immunohistochemistry. Nipples / chemistry

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  • (PMID = 19051808.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / P16 protein, human
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37. Witkiewicz A, Lee KR, Brodsky G, Cviko A, Brodsky J, Crum CP: Superficial (early) endocervical adenocarcinoma in situ: a study of 12 cases and comparison to conventional AIS. Am J Surg Pathol; 2005 Dec;29(12):1609-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Superficial (early) endocervical adenocarcinoma in situ: a study of 12 cases and comparison to conventional AIS.
  • Although established histologic criteria for the diagnosis of endocervical adenocarcinoma in situ (AIS) have been published, some lesions are not readily classified or present with more subtle degrees of epithelial atypia.
  • Lesions confined to the surface mucosa may be particularly challenging, possibly because they represent early disease.
  • Twelve cases of superficial AIS (SAIS) confined to the surface mucosa or crypt openings culled from the in-house and consultation practices were examined histologically, immunostained for MIB-1 and p16, and analyzed (when possible) for HPV nucleic acids by DNA-DNA in situ hybridization (INFORM).
  • The mean age was 26.7 years for SAIS versus 37.0 years for 42 consecutive cases of conventional AIS from the same practice (P < 0.001).
  • SAIS is an early variant of AIS that 1) occurs at a younger mean age, 2) exhibits variable atypia, and 3) arises adjacent to morphologically normal columnar epithelium.
  • Diffuse p16 expression and integrated HPV pattern are identical to that seen in more extensive forms of the disease.
  • Superficial AIS should be suspected in endocervical columnar epithelium with segmental nuclear hyperchromasia with mitotic activity, and confirmed by biomarker staining (p16 and Mib-1) if the pathologist is uncertain of the diagnosis.
  • [MeSH-major] Adenocarcinoma / pathology. Biomarkers, Tumor / analysis. Carcinoma in Situ / pathology. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Apoptosis. Biopsy. Cell Nucleus / pathology. Cervical Intraepithelial Neoplasia / diagnosis. Cervical Intraepithelial Neoplasia / metabolism. Cervical Intraepithelial Neoplasia / pathology. Cervical Intraepithelial Neoplasia / virology. Conization. Cyclin-Dependent Kinase Inhibitor p16 / analysis. DNA Probes, HPV. DNA, Neoplasm / metabolism. DNA, Viral / analysis. Female. Humans. Immunohistochemistry. In Situ Hybridization. Ki-67 Antigen / analysis. Mitosis. Papillomaviridae / genetics. Papillomaviridae / isolation & purification. Retrospective Studies


38. Dahlström LA, Ylitalo N, Sundström K, Palmgren J, Ploner A, Eloranta S, Sanjeevi CB, Andersson S, Rohan T, Dillner J, Adami HO, Sparén P: Prospective study of human papillomavirus and risk of cervical adenocarcinoma. Int J Cancer; 2010 Oct 15;127(8):1923-30
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  • [Title] Prospective study of human papillomavirus and risk of cervical adenocarcinoma.
  • However, causality inference is dependent on prospective evidence showing that exposure predicts risk for future disease.
  • Such evidence is available for squamous cell carcinoma, but not for cervical adenocarcinoma.
  • Baseline smears from women who developed adenocarcinoma during follow-up (118 women with in situ disease and 164 with invasive disease) and their individually matched controls (1,434 smears) were analyzed for HPV using PCR.
  • Conditional logistic regression was used to estimate odds ratios (OR) of future adenocarcinoma with 95% confidence intervals (CI).
  • Being positive for HPV 16 in the first cytologically normal smear was associated with increased risks for both future adenocarcinoma in situ (OR: 11.0, 95% CI: 2.6-46.8) and invasive adenocarcinoma (OR: 16.0, 95% CI: 3.8-66.7), compared to being negative for HPV 16.
  • Similarly, an HPV 18 positive smear was associated with increased risks for adenocarcinoma in situ (OR: 26.0, 95% CI: 3.5-192) and invasive adenocarcinoma (OR: 28.0, 95% CI: 3.8-206), compared to an HPV 18 negative smear.
  • Being positive for HPV 16/18 in 2 subsequent smears was associated with an infinite risk of both in situ and invasive adenocarcinoma.
  • In conclusion, infections with HPV 16 and 18 are detectable up to at least 14 years before diagnosis of cervical adenocarcinoma.
  • Our data provide prospective evidence that the association of HPV 16/18 with cervical adenocarcinoma is strong and causal.

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  • [Cites] Br J Cancer. 2005 Nov 28;93(11):1301-4 [16265348.001]
  • [Cites] Int J Cancer. 2000 May 1;86(3):429-35 [10760834.001]
  • [Cites] J Natl Cancer Inst. 2006 Mar 1;98(5):303-15 [16507827.001]
  • [Cites] Int J Gynecol Cancer. 2006 May-Jun;16(3):1025-31 [16803480.001]
  • [Cites] Int J Cancer. 2007 Feb 15;120(4):885-91 [17131323.001]
  • [Cites] J Natl Cancer Inst. 2008 May 7;100(9):622-9 [18445828.001]
  • [Cites] J Clin Microbiol. 2009 Mar;47(3):541-6 [19144817.001]
  • [Cites] Int J Cancer. 2009 Aug 1;125(3):525-9 [19449379.001]
  • [Cites] Am J Pathol. 2000 Oct;157(4):1055-62 [11021808.001]
  • [Cites] Cancer Res. 2000 Nov 1;60(21):6027-32 [11085523.001]
  • [Cites] Eur J Cancer. 2001 Jan;37(2):246-50 [11166153.001]
  • [Cites] Br J Cancer. 2003 Jan 13;88(1):63-73 [12556961.001]
  • [Cites] J Pathol. 2003 Dec;201(4):535-43 [14648656.001]
  • [Cites] Biometrics. 1988 Jun;44(2):355-67 [3390504.001]
  • [Cites] Br J Cancer. 1995 Aug;72(2):498-505 [7640239.001]
  • [Cites] Anal Quant Cytol Histol. 1995 Aug;17(4):221-9 [8526946.001]
  • [Cites] J Gen Virol. 1995 Apr;76 ( Pt 4):1057-62 [9049358.001]
  • [Cites] Cancer Causes Control. 1997 Sep;8(5):755-63 [9328198.001]
  • [Cites] Int J Cancer. 1998 Feb 9;75(4):536-45 [9466653.001]
  • [Cites] Br J Cancer. 1999 Sep;81(1):159-66 [10487628.001]
  • [Cites] Cancer Detect Prev. 2004;28(6):461-4 [15582270.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2191-9 [16172231.001]
  • [Cites] Br J Cancer. 2006 Jan 16;94(1):171-5 [16404371.001]
  • (PMID = 20473898.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA093378-01A1; United States / NCI NIH HHS / CA / R01 CA093378-01A1; United States / NCI NIH HHS / CA / R01 CA111720-01; United States / NCI NIH HHS / CA / CA111720-02; United States / NCI NIH HHS / CA / CA111720-01; United States / NCI NIH HHS / CA / 1R01CA93378-01A1; United States / NCI NIH HHS / CA / R01CA111720-02; United States / NCI NIH HHS / CA / R01 CA111720-02; United States / NCI NIH HHS / CA / R01 CA093378; United States / NCI NIH HHS / CA / R01CA111720-01; United States / NCI NIH HHS / CA / 5R01CA111720-03; United States / NCI NIH HHS / CA / R01 CA111720-03; United States / NCI NIH HHS / CA / R01 CA111720; United States / NCI NIH HHS / CA / CA111720-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral
  • [Other-IDs] NLM/ NIHMS207185; NLM/ PMC2930102
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39. Simon SK, Bolanca IK, Sentija K, Kukura V, Valetić J, Skrtić A: Vulvar Paget's disease--a case report. Coll Antropol; 2010 Jun;34(2):649-52
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  • [Title] Vulvar Paget's disease--a case report.
  • Vulvar Morbus Paget (MP) represents a rare intraepithelial adenocarcinoma.
  • Histologically it is analogous to Paget's disease of the breast.
  • Occasionally, single anaplastic Paget's cells can be found on the vulvar smears which make cytological diagnosis of the disease possible.
  • However, the disease can be diagnosed only by biopsy.
  • Accordingly, cytological diagnosis vulvar intraepithelial neoplasia (VIN III) with differential diagnosis of vulvar Paget's disease was made.
  • The pathological verification supported the diagnosis of MP and an immunohistochemistry panel confirmed type III of Paget's disease and an evaluation of bladder was suggested.
  • [MeSH-major] Paget Disease, Extramammary / pathology. Vulvar Diseases / pathology

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  • (PMID = 20698146.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
  • [Chemical-registry-number] 0 / Keratin-7
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40. Gari A, Lotocki R, Krepart G, Popowich S, Demers A: Cervical cancer in the province of Manitoba: a 30-year experience. J Obstet Gynaecol Can; 2008 Sep;30(9):788-795
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  • RESULTS: Over this 30-year span, invasive cervical cancer was diagnosed in 1927 women, and carcinoma in situ was diagnosed in 10 006 women.
  • Cervical cancer was the fifth most frequent cancer diagnosis for women in 1970, and by 1999 it had become the eleventh most frequent.
  • Squamous cell carcinoma (SCC) was the most frequently diagnosed histologic subtype, but its incidence decreased from 1970 to 1999; the proportion of women with adenocarcinoma increased gradually over the same time from 7% to 22%.
  • Survival rates were comparable in women with SCC and adenocarcinoma.
  • However, the incidence of cervical carcinoma in situ has increased steadily during the same period.
  • Squamous cell carcinoma is still the most frequently diagnosed subtype of invasive cervical cancer, but the proportion of women with adenocarcinoma has increased.
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adult. Aged. Carcinoma in Situ / epidemiology. Carcinoma, Squamous Cell / epidemiology. Female. Humans. Incidence. Manitoba / epidemiology. Middle Aged. Registries. Young Adult

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  • (PMID = 18845048.001).
  • [ISSN] 1701-2163
  • [Journal-full-title] Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
  • [ISO-abbreviation] J Obstet Gynaecol Can
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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41. Wallace MB, Sharma P, Lightdale C, Wolfsen H, Coron E, Buchner A, Bajbouj M, Bansal A, Rastogi A, Abrams J, Crook JE, Meining A: Preliminary accuracy and interobserver agreement for the detection of intraepithelial neoplasia in Barrett's esophagus with probe-based confocal laser endomicroscopy. Gastrointest Endosc; 2010 Jul;72(1):19-24
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  • [Title] Preliminary accuracy and interobserver agreement for the detection of intraepithelial neoplasia in Barrett's esophagus with probe-based confocal laser endomicroscopy.
  • PATIENTS: This study involved nonconsecutive patients undergoing BE surveillance or evaluation of high-grade intraepithelial neoplasia or early adenocarcinoma.
  • MAIN OUTCOME MEASUREMENTS: Sensitivity, specificity, and agreement for the pCLE diagnosis of high-grade intraepithelial neoplasia or carcinoma.
  • RESULTS: In the validation set (n = 20), 11 cases had high-grade intraepithelial neoplasia or invasive carcinoma.
  • The sensitivity for the diagnosis of neoplasia for the 11 endoscopists was 88% (range 6 of 11 to 11 of 11), and the specificity was 96% (range 7 of 9 to 9 of 9).
  • There was substantial agreement on the pCLE diagnosis (86%, kappa 0.72; 95% confidence interval, 0.58-0.86).
  • CONCLUSION: Results suggest that pCLE for the diagnosis of neoplasia in BE has very high accuracy and reliability.

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  • [Copyright] Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
  • [Cites] Gastrointest Endosc. 2008 Aug;68(2):319-23 [18436217.001]
  • [Cites] Gastroenterology. 2008 Jul;135(1):24-31 [18442484.001]
  • [Cites] Gut. 2000 Aug;47(2):251-5 [10896917.001]
  • [Cites] Gastrointest Endosc. 2001 Mar;53(3):294-9 [11231386.001]
  • [Cites] Am J Gastroenterol. 2002 Aug;97(8):1888-95 [12190150.001]
  • [Cites] Biometrics. 1977 Mar;33(1):159-74 [843571.001]
  • [Cites] Gastroenterol Clin North Am. 1997 Sep;26(3):487-94 [9309399.001]
  • [Cites] Endoscopy. 2005 Oct;37(10):929-36 [16189764.001]
  • [Cites] Gastrointest Endosc. 2006 Aug;64(2):155-66 [16860062.001]
  • [Cites] Gastrointest Endosc. 2006 Aug;64(2):176-85 [16860064.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Aug;4(8):979-87 [16843068.001]
  • [Cites] Gastrointest Endosc. 2007 Nov;66(5):1001-7 [17767932.001]
  • [Cites] Clin Gastroenterol Hepatol. 2007 Nov;5(11):1261-7 [17689297.001]
  • [Cites] Gastroenterology. 2008 Mar;134(3):670-9 [18242603.001]
  • [Cites] Am J Gastroenterol. 2008 Mar;103(3):788-97 [18341497.001]
  • [Cites] Gut. 2008 Dec;57(12):1648-53 [18755886.001]
  • (PMID = 20381042.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA132892-04; United States / NCI NIH HHS / CA / K07 CA132892; United States / NCI NIH HHS / CA / K07 CA132892-04
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS307179; NLM/ PMC3144146
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42. Layfield LJ, Jarboe EA: Cytopathology of the pancreas: neoplastic and nonneoplastic entities. Ann Diagn Pathol; 2010 Apr;14(2):140-51
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  • Whereas separation of neuroendocrine, acinar, and ductal neoplasms is usually straightforward, the greatest diagnostic challenge in pancreatic fine-needle aspiration is the separation of atypical epithelium secondary to chronic pancreatitis from well-differentiated ductal adenocarcinoma.
  • Recently, a number of in situ lesions have been identified, complicating the cytologic diagnosis of pancreatic neoplasia.
  • These noninvasive lesions include pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasm.

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20227021.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 85
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43. Ooi A, Zen Y, Ninomiya I, Tajiri R, Suzuki S, Kobayashi H, Imoto I, Dobashi Y: Gene amplification of ERBB2 and EGFR in adenocarcinoma in situ and intramucosal adenocarcinoma of Barrett's esophagus. Pathol Int; 2010 Jun;60(6):466-71
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  • [Title] Gene amplification of ERBB2 and EGFR in adenocarcinoma in situ and intramucosal adenocarcinoma of Barrett's esophagus.
  • We examined 11 cases of carcinoma arising from Barrett's esophagus consisting of two adenocarcinomas in situ (ACIS), two intramucosal adenocarcinomas, and seven overt invasive adenocarcinomas.
  • Overexpression of p53 (implying a mutation of the p53 gene), ERBB2, and EGFR was measured by immunohistochemistry, and gene amplification of ERBB2 and EGFR was measured by fluorescence in situ hybridization (FISH).
  • In all cases of ACIS and the intramucosal adenocarcinomas, almost all cancer cells overexpressed p53, however the populations overexpressing ERBB2 and EGFR varied in different cases: in one ACIS, ERBB2 was coexpressed in all the cancer cells, in the other ACIS and one intramucosal adenocarcinoma, ERBB2 was overexpressed in about 50% and only 10% of the p53-positive cells respectively.
  • EGFR was co-expressed in 20% in the other intramucosal adenocarcinoma.
  • These gene amplifications, however, were not found in the seven invasive adenocarcinomas.
  • [MeSH-major] Adenocarcinoma / genetics. Barrett Esophagus / genetics. Carcinoma in Situ / genetics. Gene Amplification. Receptor, Epidermal Growth Factor / genetics. Receptor, ErbB-2 / genetics
  • [MeSH-minor] Esophagus / metabolism. Esophagus / pathology. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Mucous Membrane / metabolism. Mucous Membrane / pathology. Neoplasm Invasiveness / genetics. Tumor Suppressor Protein p53 / genetics. Tumor Suppressor Protein p53 / metabolism


44. Dhillon PK, Barry M, Stampfer MJ, Perner S, Fiorentino M, Fornari A, Ma J, Fleet J, Kurth T, Rubin MA, Mucci LA: Aberrant cytoplasmic expression of p63 and prostate cancer mortality. Cancer Epidemiol Biomarkers Prev; 2009 Feb;18(2):595-600
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  • Recent studies suggest that it may also distinguish aggressive prostate cancer with down-regulated expression occurring in men with more advanced disease.
  • The positive trend remained significant (P = 0.047) after multivariable adjustment for age, year of diagnosis, and Gleason score.
  • We found aberrant expression of p63 in the cytoplasm to be associated with increased prostate cancer-specific mortality up to 20 years after diagnosis.

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  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1424-32 [15941951.001]
  • [Cites] Hum Pathol. 2005 Feb;36(2):187-94 [15754296.001]
  • [Cites] BMC Bioinformatics. 2005;6:304 [16364175.001]
  • [Cites] Neoplasia. 2006 Jan;8(1):59-68 [16533427.001]
  • [Cites] BJU Int. 2006 May;97(5):1109-15 [16643500.001]
  • [Cites] Histopathology. 2006 Oct;49(4):349-57 [16978197.001]
  • [Cites] Cell Cycle. 2007 Feb 1;6(3):300-4 [17264676.001]
  • [Cites] Oncogene. 2007 Apr 2;26(15):2220-5 [17401431.001]
  • [Cites] J Biol Chem. 2007 May 11;282(19):14616-25 [17371868.001]
  • [Cites] Ann Oncol. 2008 Mar;19(3):501-7 [17998283.001]
  • [Cites] Am J Surg Pathol. 2008 Mar;32(3):461-7 [18300803.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1682-8 [18583469.001]
  • [Cites] Ann Epidemiol. 2000 Feb;10(2):125-34 [10691066.001]
  • [Cites] Nat Cell Biol. 2000 Sep;2(9):569-73 [10980696.001]
  • [Cites] Biochim Biophys Acta. 2000 Jul 31;1471(1):M31-41 [10967423.001]
  • [Cites] Am J Pathol. 2000 Dec;157(6):1769-75 [11106548.001]
  • [Cites] DNA Cell Biol. 2001 Jun;20(6):321-30 [11445003.001]
  • [Cites] Urology. 2001 Oct;58(4):619-24 [11597556.001]
  • [Cites] J Biol Chem. 2001 Nov 30;276(48):45255-60 [11572869.001]
  • [Cites] Clin Cancer Res. 2002 Feb;8(2):494-501 [11839669.001]
  • [Cites] Am J Surg Pathol. 2002 Mar;26(3):312-9 [11859202.001]
  • [Cites] J Biol Chem. 2002 Apr 26;277(17):15053-60 [11847229.001]
  • [Cites] Am J Surg Pathol. 2002 Sep;26(9):1151-60 [12218571.001]
  • [Cites] Am J Surg Pathol. 2002 Sep;26(9):1161-8 [12218572.001]
  • [Cites] Am J Pathol. 2002 Oct;161(4):1199-206 [12368193.001]
  • [Cites] Exp Cell Res. 2003 Jan 15;282(2):59-69 [12531692.001]
  • [Cites] Urology. 2004 Jun;63(6):1079-83 [15183954.001]
  • [Cites] N Engl J Med. 1989 Jul 20;321(3):129-35 [2664509.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7262-6 [1353891.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1993;423(6):443-8 [8291217.001]
  • [Cites] Am J Pathol. 1995 Sep;147(3):790-8 [7677190.001]
  • [Cites] Mol Cell Biol. 1996 Mar;16(3):1126-37 [8622657.001]
  • [Cites] Nature. 1997 May 15;387(6630):296-9 [9153395.001]
  • [Cites] EMBO J. 1998 Jan 15;17(2):554-64 [9430646.001]
  • [Cites] Nat Med. 1998 Jul;4(7):747-8 [9662346.001]
  • [Cites] Urology. 1998 Oct;52(4):594-601 [9763077.001]
  • [Cites] Mol Cell. 1998 Sep;2(3):305-16 [9774969.001]
  • [Cites] J Exp Med. 1998 Nov 2;188(9):1763-8 [9802988.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3077-80 [10077639.001]
  • [Cites] Nature. 1999 Apr 22;398(6729):714-8 [10227294.001]
  • [Cites] Oncogene. 1999 Aug 12;18(32):4606-15 [10467405.001]
  • [Cites] Genes Dev. 2005 Sep 1;19(17):1986-99 [16107615.001]
  • (PMID = 19155438.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA-40360; United States / NCI NIH HHS / CA / CA-34944; United States / NCI NIH HHS / CA / R01 CA040360-17; United States / NHLBI NIH HHS / HL / HL-34595; United States / NHLBI NIH HHS / HL / HL-26490; United States / NCI NIH HHS / CA / T32 CA009001-33; United States / NCI NIH HHS / CA / R01 CA090598; United States / NCI NIH HHS / CA / R01 CA097193-07; United States / NHLBI NIH HHS / HL / R01 HL034595; United States / NCI NIH HHS / CA / CA009001-33; United States / NCI NIH HHS / CA / CA097193-07; United States / NCI NIH HHS / CA / R01 CA034944-03; United States / NCI NIH HHS / CA / R01 CA090598-05; United States / NHLBI NIH HHS / HL / R01 HL026490; United States / NCI NIH HHS / CA / CA090598-05; United States / NCI NIH HHS / CA / T32 CA009001; United States / NHLBI NIH HHS / HL / R01 HL034595-07; United States / NCI NIH HHS / CA / CA-097193; United States / NCI NIH HHS / CA / R01 CA040360; United States / NHLBI NIH HHS / HL / R01 HL026490-03; United States / NCI NIH HHS / CA / R01 CA097193; United States / NCI NIH HHS / CA / R01 CA034944; United States / NCI NIH HHS / CA / 5R01 CA090598
  • [Publication-type] Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CKAP4 protein, human; 0 / Ki-67 Antigen; 0 / Membrane Proteins
  • [Other-IDs] NLM/ NIHMS107808; NLM/ PMC2692093
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45. Gabrecht T, Glanzmann T, Freitag L, Weber BC, van den Bergh H, Wagnières G: Optimized autofluorescence bronchoscopy using additional backscattered red light. J Biomed Opt; 2007 Nov-Dec;12(6):064016
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Bronchoscopy / methods
  • [MeSH-minor] Adenocarcinoma / diagnosis. Bronchi / pathology. Bronchoscopes. Carcinoma in Situ / diagnosis. Carcinoma, Small Cell / diagnosis. Carcinoma, Squamous Cell / diagnosis. Fluorescence. Humans. Image Processing, Computer-Assisted. Light. Lung Neoplasms / diagnosis. Metaplasia / diagnosis. Predictive Value of Tests. Scattering, Radiation. Spectrometry, Fluorescence

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  • (PMID = 18163832.001).
  • [ISSN] 1083-3668
  • [Journal-full-title] Journal of biomedical optics
  • [ISO-abbreviation] J Biomed Opt
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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46. Graesslin O, Dedecker F, Collinet P, Jouve E, Urbaniack D, Leroy JL, Boulanger JC, Quéreux C: [Management of in situ cervical adenocarcinoma]. Gynecol Obstet Fertil; 2006 Dec;34(12):1178-84
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  • [Title] [Management of in situ cervical adenocarcinoma].
  • [Transliterated title] Prise en charge de l'adénocarcinome in situ du col utérin.
  • The management of adenocarcinoma in situ of the cervix (ACIS) is difficult because it is often diagnosed in younger women who may wish to preserve their potential of fertility.
  • We report a complete review of the literature on this subject where conservative attitude appears possible but is associated with recurrence risk (5 to 10%) and invasive disease (2%).
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma in Situ / surgery. Colposcopy / methods. Reproduction. Uterine Cervical Neoplasms / surgery


47. Sahoo S, Recant WM: Triad of columnar cell alteration, lobular carcinoma in situ, and tubular carcinoma of the breast. Breast J; 2005 Mar-Apr;11(2):140-2
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  • [Title] Triad of columnar cell alteration, lobular carcinoma in situ, and tubular carcinoma of the breast.
  • Columnar cell alteration in the breast encompasses a spectrum of pathologic changes ranging from simple columnar cell change to more complex columnar cell hyperplasia with and without atypia to in situ carcinoma, often with a micropapillary architecture.
  • For reasons that remain unclear, the columnar cell lesions are associated with tubular carcinomas and lobular carcinoma in situ.
  • [MeSH-major] Adenocarcinoma / pathology. Breast Neoplasms / pathology. Carcinoma in Situ / pathology. Fibrocystic Breast Disease / pathology. Precancerous Conditions / pathology
  • [MeSH-minor] Adult. Breast / pathology. Calcinosis / pathology. Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 15730461.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Canchola AJ, Horn-Ross PL, Purdie DM: Risk of second primary malignancies in women with papillary thyroid cancer. Am J Epidemiol; 2006 Mar 15;163(6):521-7
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  • Second malignancies in women diagnosed with thyroid cancer are of concern given the young average age at diagnosis and excellent survival.
  • Follow-up was calculated from 2 months until the diagnosis of a second primary cancer, death, loss to follow-up, or December 31, 1999, whichever occurred first.
  • An excess of in situ breast cancer (SIR = 1.6, 95% CI: 1.0, 2.4), kidney cancer (SIR = 3.9, 95% CI: 2.2, 6.3), and melanoma (SIR = 2.1, 95% CI: 1.3, 3.2) limited to the first 5 years after diagnosis was observed.
  • Women with papillary thyroid cancer are at increased risk of in situ, but not invasive, breast cancer, kidney cancer, and melanoma.
  • [MeSH-major] Adenocarcinoma, Papillary / epidemiology. Breast Neoplasms / epidemiology. Kidney Neoplasms / epidemiology. Melanoma / epidemiology. Neoplasms, Second Primary / epidemiology. Thyroid Neoplasms / epidemiology


49. Roberts JM, Thurloe JK, Biro C, Hyne SG, Williams KE, Bowditch RC: Follow-up of cytologic predictions of endocervical glandular abnormalities: histologic outcomes in 123 cases. J Low Genit Tract Dis; 2005 Apr;9(2):71-7
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  • MATERIALS AND METHODS: We obtained histologic follow-up for 100% of 67 cytologic predictions of adenocarcinoma in situ (AIS) and 82% of 39 predictions of possible AIS (?AIS) made over a 4-year period (1999-2002) and for 25% of 105 atypical endocervical cells (AEC) predictions over a 12-month period (2000).
  • RESULTS: PPVs for predictions of AIS and ?AIS for high-grade lesions overall were 91% and 75% (p = .032), respectively, and those for high-grade glandular lesions were 88% and 72% (p = .046), respectively.
  • CONCLUSION: Cytology can accurately predict AIS.
  • [MeSH-major] Adenocarcinoma / diagnosis. Carcinoma in Situ / diagnosis. Uterine Cervical Neoplasms / diagnosis


50. Katabi N, Klimstra DS: Intraductal papillary mucinous neoplasms of the pancreas: clinical and pathological features and diagnostic approach. J Clin Pathol; 2008 Dec;61(12):1303-13
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  • There is marked overlap between IPMNs and pancreatic intraepithelial neoplasia (PanIN), such that the distinction between these two lesions is nearly impossible in certain cases.
  • As a result, the correct diagnosis of IPMN can be challenging.
  • This review addresses the clinical and pathological features of IPMNs, emphasising their diagnostic criteria, differential diagnosis and biological behaviour.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Carcinoma in Situ / diagnosis. Diagnosis, Differential. Humans. Neoplasm Invasiveness. Pancreatectomy. Prognosis

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  • (PMID = 18703569.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 73
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51. Lantuejoul S, Raynaud C, Salameire D, Gazzeri S, Moro-Sibilot D, Soria JC, Brambilla C, Brambilla E: Telomere maintenance and DNA damage responses during lung carcinogenesis. Clin Cancer Res; 2010 Jun 1;16(11):2979-88
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  • EXPERIMENTAL DESIGN: We have evaluated telomere length by fluorescence in situ hybridization and analyzed DDR proteins p-CHK2, p-ATM, and p-H2AX, and telomeric maintenance proteins TRF1 and TRF2 expression by immunohistochemistry in normal bronchial/bronchiolar epithelium, and in 109 bronchial preneoplastic lesions, in comparison with 32 squamous invasive carcinoma (SCC), and in 27 atypical alveolar hyperplasia (AAH) in comparison with 6 adenocarcinoma in situ (AIS; formerly bronchiolo-alveolar carcinoma) and 24 invasive adenocarcinoma (ADC).
  • RESULTS: Telomere length critically shortened at bronchial metaplasia stage to increase gradually from dysplasia to invasive SCC; in bronchiolo-alveolar lesions, telomere length decreased from normal to AIS and increased from stage I to II to stage III to IV ADC.
  • The expression of concomitant DDR proteins increased significantly from low- to high-grade dysplasia and from AAH to AIS and stage I to II ADC.
  • [MeSH-major] Adenocarcinoma / genetics. Adenocarcinoma, Bronchiolo-Alveolar / genetics. DNA Damage. Lung Neoplasms / genetics. Precancerous Conditions / genetics. Telomere / ultrastructure
  • [MeSH-minor] Ataxia Telangiectasia Mutated Proteins. Carcinoma, Squamous Cell / genetics. Cell Cycle Proteins / metabolism. Checkpoint Kinase 2. DNA-Binding Proteins / metabolism. Disease Progression. Histones / metabolism. Hyperplasia / pathology. Immunohistochemistry. Lung / metabolism. Lung / pathology. Protein-Serine-Threonine Kinases / metabolism. Telomeric Repeat Binding Protein 1 / metabolism. Telomeric Repeat Binding Protein 2 / metabolism. Tumor Suppressor Proteins / metabolism

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  • [Copyright] Copyright 2010 AACR.
  • (PMID = 20404006.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / DNA-Binding Proteins; 0 / H2AFX protein, human; 0 / Histones; 0 / TERF2 protein, human; 0 / Telomeric Repeat Binding Protein 1; 0 / Telomeric Repeat Binding Protein 2; 0 / Tumor Suppressor Proteins; EC 2.7.1.11 / Checkpoint Kinase 2; EC 2.7.11.1 / ATM protein, human; EC 2.7.11.1 / Ataxia Telangiectasia Mutated Proteins; EC 2.7.11.1 / CHEK2 protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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52. Powell RD, Pettay JD, Powell WC, Roche PC, Grogan TM, Hainfeld JF, Tubbs RR: Metallographic in situ hybridization. Hum Pathol; 2007 Aug;38(8):1145-59
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  • [Title] Metallographic in situ hybridization.
  • Metallographic methods, in which a target is visualized using a probe or antibody that deposits metal selectively at its binding site, offers many advantages for bright-field in situ hybridization (ISH) detection as well as for other labeling and detection methods.
  • [MeSH-major] Gold Colloid / chemistry. In Situ Hybridization / methods. Nucleic Acids / chemistry. Silver Compounds / chemistry. Silver Staining / methods
  • [MeSH-minor] Adenocarcinoma / chemistry. Adenocarcinoma / diagnosis. Adenocarcinoma / genetics. Breast Neoplasms / chemistry. Breast Neoplasms / diagnosis. Breast Neoplasms / genetics. Enzymes / chemistry. Female. Humans. Receptor, ErbB-2 / analysis. Receptor, ErbB-2 / genetics

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  • (PMID = 17640553.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / 1R43CA111182-01; United States / NCI NIH HHS / CA / 5R42CA83618-03; United States / NIGMS NIH HHS / GM / 5R44 GM064257-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Enzymes; 0 / Gold Colloid; 0 / Nucleic Acids; 0 / Silver Compounds; EC 2.7.10.1 / Receptor, ErbB-2
  • [Number-of-references] 125
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53. Ault KA, Future II Study Group: Effect of prophylactic human papillomavirus L1 virus-like-particle vaccine on risk of cervical intraepithelial neoplasia grade 2, grade 3, and adenocarcinoma in situ: a combined analysis of four randomised clinical trials. Lancet; 2007 Jun 2;369(9576):1861-8
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  • [Title] Effect of prophylactic human papillomavirus L1 virus-like-particle vaccine on risk of cervical intraepithelial neoplasia grade 2, grade 3, and adenocarcinoma in situ: a combined analysis of four randomised clinical trials.
  • BACKGROUND: Cervical cancer and its obligate precursors, cervical intraepithelial neoplasia grades 2 and 3 (CIN2/3), and adenocarcinona in situ (AIS), are caused by oncogenic human papillomavirus (HPV).
  • The primary composite endpoint was the combined incidence of HPV16/18-related CIN2/3, AIS, or cervical cancer.
  • In a second intention-to-treat analysis we noted an 18% reduction (95% CI 7-29) in the overall rate of CIN2/3 or AIS due to any HPV type.
  • [MeSH-major] Adenocarcinoma / prevention & control. Cervical Intraepithelial Neoplasia / prevention & control. Papillomavirus Vaccines

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  • [CommentIn] Lancet. 2007 Sep 22;370(9592):1031; author reply 1032-3 [17889237.001]
  • [CommentIn] Lancet. 2007 Jun 2;369(9576):1837-9 [17544748.001]
  • [CommentIn] Evid Based Med. 2007 Dec;12(6):168 [18063728.001]
  • [CommentIn] Lancet. 2007 Sep 22;370(9592):1031-2; author reply 1032-3 [17889236.001]
  • (PMID = 17544766.001).
  • [ISSN] 1474-547X
  • [Journal-full-title] Lancet (London, England)
  • [ISO-abbreviation] Lancet
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT00092521/ NCT00092534/ NCT00365378/ NCT00365716
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Papillomavirus Vaccines
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54. Kettunen E, Salmenkivi K, Vuopala K, Toljamo T, Kuosma E, Norppa H, Knuutila S, Kaleva S, Huuskonen MS, Anttila S: Copy number gains on 5p15, 6p11-q11, 7p12, and 8q24 are rare in sputum cells of individuals at high risk of lung cancer. Lung Cancer; 2006 Nov;54(2):169-76
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  • Such alterations have been utilized in design of fluorescence in situ hybridization (FISH) probe sets in attempts to improve the cytological diagnosis of lung cancer.
  • CONCLUSIONS: FISH did not significantly exceed the sensitivity of sputum cytology in finding lung cancers.
  • [MeSH-major] Adenocarcinoma / genetics. Chromosome Aberrations. Lung Neoplasms / genetics. Sputum / cytology
  • [MeSH-minor] Adult. Aged. Asbestos / toxicity. Bronchi. Female. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Risk. Sensitivity and Specificity. Smoking / adverse effects

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  • (PMID = 16935392.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 1332-21-4 / Asbestos
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55. Kantathavorn N, Kietpeerakool C, Suprasert P, Srisomboon J, Khunamornpong S, Nimmanhaeminda K, Siriaungkul S: Clinical relevance of atypical squamous cells of undetermined significance by the 2001 bethesda system: experience from a cervical cancer high incidence region. Asian Pac J Cancer Prev; 2008 Oct-Dec;9(4):785-8
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  • The aim of this study was to evaluate the underlying lesions and factors predicting cervical intraepithelial neoplasia (CIN) 2+ in women who had 'atypical squamous cells of undetermined significance' (ASC-US) on cervical cytology in the region with a high incidence of cervical cancer.
  • The histopathologic results at the initial evaluation were as follows: CIN 2-3, 21 (10.1%); adenocarcinoma in situ, 3 (1.4%); cancer, 5 (2.4%); CIN 1, 26 (12.5%); and no lesions, 153 (73.6%).
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Cervical Intraepithelial Neoplasia / pathology. Neoplasm Staging / methods. Uterine Cervical Neoplasms / pathology


56. Takeda Y, Nakase H, Mikami S, Inoue T, Satou S, Sakai Y, Chiba T: Possible link between ulcerative colitis and in situ adenocarcinoma of an appendiceal mucocele: importance of inflammation in the appendiceal orifice related to UC. Inflamm Bowel Dis; 2008 Jun;14(6):873-4
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  • [Title] Possible link between ulcerative colitis and in situ adenocarcinoma of an appendiceal mucocele: importance of inflammation in the appendiceal orifice related to UC.
  • [MeSH-major] Adenocarcinoma / complications. Appendix. Colitis, Ulcerative / complications. Mucocele / etiology

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  • [CommentIn] Inflamm Bowel Dis. 2009 Sep;15(9):1283 [18951377.001]
  • (PMID = 18275069.001).
  • [ISSN] 1078-0998
  • [Journal-full-title] Inflammatory bowel diseases
  • [ISO-abbreviation] Inflamm. Bowel Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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57. Virich G, Gudi V, Canal A: Extramammary Paget's disease--occupational exposure to used engine oil and a new skin grafting technique. J Plast Reconstr Aesthet Surg; 2008 Dec;61(12):1528-9
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  • [Title] Extramammary Paget's disease--occupational exposure to used engine oil and a new skin grafting technique.
  • SUMMARY: Extramammary Paget's disease (EMPD) is a rare intraepithelial adenocarcinoma, affecting mainly 50-70-year-olds with a female preponderance of 3:1.
  • [MeSH-major] Occupational Diseases / chemically induced. Oils / toxicity. Paget Disease, Extramammary / chemically induced. Skin Neoplasms / chemically induced. Skin Transplantation / methods

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  • (PMID = 17766206.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Oils; 0 / Polycyclic Hydrocarbons, Aromatic
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58. Sireci AN, Crapanzano JP, Mansukhani M, Wright T, Babiac A, Erroll M, Vazquez M, Saqi A: Atypical glandular cells (AGC): ThinPrep Imaging System (TIS), manual screening (MS), and correlation with Hybrid Capture 2 (HC2) HPV DNA testing. Diagn Cytopathol; 2010 Oct;38(10):705-9
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  • OBJECTIVE: The aim of the study was to determine if the ThinPrep Imaging System (T1S) improves the positive predictive value (PPV) of atypical glandular cell (AGC) diagnosis for identifying HPV-related squamous and/or glandular lesions over manual screening (MS), and if human papilloma virus (HPV)-DNA testing improves the diagnostic yield.
  • MATERIALS AND METHODS: 85 ThinPrep cervical cytology specimens with a diagnosis of AGC by TIS (n = 51) and MS (n = 34) were retrieved.
  • In the MS group, more cases of glandular pathology were identified, however only three represented adenocarcinoma in-situ (AIS), and the remaining ten were endometrial carcinomas (EMCA).
  • Although the MS group harbored more glandular pathology, the differences in the detection of AIS were not statistically significant.
  • [MeSH-major] Cervical Intraepithelial Neoplasia / diagnosis. DNA, Viral / analysis. Endometrial Neoplasms / diagnosis. Image Interpretation, Computer-Assisted / methods. Precancerous Conditions / diagnosis

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  • [Copyright] © 2009 Wiley-Liss, Inc.
  • (PMID = 20014311.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral
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59. Borgonovo G, Razzetta F, Assalino M, Varaldo E, Puglisi M, Ceppa P: Rectal hepatoid carcinoma with liver metastases in a patient affected by ulcerative colitis. Hepatobiliary Pancreat Dis Int; 2008 Oct;7(5):539-43
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  • We present a case of rectal hepatoid adenocarcinoma with metachronous liver metastases.
  • METHODS: Four months after total procto-colectomy for a rectal adenocarcinoma (Astler-Coller C2), a 42-year-old man with ulcerative colitis showed hypoechoic masses in the hepatic parenchyma by abdominal ultrasonography.
  • RESULTS: Immunohistochemistry and albumin mRNA in situ hybridization suggested that the nodules were metastases of a HT.
  • He died from liver failure 19 months after initial diagnosis.
  • The preoperative diagnosis of this tumor requires a high degree of suspicion, the availability of a panel of immunohistochemical markers, and a certain amount of luck.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Hepatocellular / secondary. Colitis, Ulcerative / complications. Liver Neoplasms / secondary. Rectal Neoplasms / pathology


60. Argani P, Netto GJ, Parwani AV: Papillary renal cell carcinoma with low-grade spindle cell foci: a mimic of mucinous tubular and spindle cell carcinoma. Am J Surg Pathol; 2008 Sep;32(9):1353-9
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  • The solid variant of papillary renal cell carcinoma (PRCC) is distinguishable genetically from mucinous tubular and spindle cell carcinoma (MTSC) of the kidney by the presence of trisomy for chromosomes 7 and 17; however, at the morphologic and immunohistochemical levels, these neoplasms overlap significantly.
  • The key morphologic feature distinguishing these two is thought to be the low grade of the spindle cell areas of MTSC; spindle cell areas in PRCC generally signify sarcomatoid change and are high grade.
  • All 5 cases showed trisomy of chromosome 7, and 3 of 5 showed trisomy of chromosome 17 by fluorescence in situ hybridization, supporting classification as PRCC.
  • These cases further reported morphologic overlap between MTSC and PRCC.
  • Before a diagnosis of metastatic MTSC or MTSC with unusual morphology is rendered, the possibility of PRCC with low-grade spindle cell foci should be considered.
  • Fluorescence in situ hybridization analysis effectively separates these morphologically very similar yet genetically distinctive entities.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Chromosomes, Human, Pair 17 / genetics. Chromosomes, Human, Pair 7 / genetics. Diagnosis, Differential. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Male. Middle Aged. Trisomy


61. Quddus MR, Zhang C, Sung CJ, Ramos D, Lawrence WD: Intraepithelial mucinous carcinoma arising in an endocervical-type mucinous polypoid adenomyoma of the uterine corpus: a case report. J Reprod Med; 2005 Aug;50(8):643-6
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  • [Title] Intraepithelial mucinous carcinoma arising in an endocervical-type mucinous polypoid adenomyoma of the uterine corpus: a case report.
  • We report a case of intraepithelial mucinous adenocarcinoma arising in an endocervical-type mucinous adenomyoma of the uterine corpus in a previously healthy woman.
  • The mucinous glandular epithelium showed a spectrum of architectural and cytologic changes ranging from benign to severe atypia and occasional back-to-back cribriform glands, consistent with adenocarcinoma.
  • A diagnosis was made of intraepithelial adenocarcinoma arising in a mucinous adenomyoma in the uterine corpus.
  • CONCLUSION: Endocervical-type mucinous adenomyoma, although previously reported as a benign entity, may contain areas of adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Adenomyoma / diagnosis. Neoplasms, Second Primary / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Endometrium / pathology. Epithelium / pathology. Female. Humans. Hysterectomy. In Situ Hybridization. Middle Aged. Muscle, Smooth / pathology. Polyps / diagnosis. Polyps / pathology. Polyps / surgery. Treatment Outcome. Uterine Hemorrhage / diagnosis. Uterine Hemorrhage / etiology. Uterine Hemorrhage / pathology

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  • (PMID = 16220776.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Laucirica R, Bentz JS, Souers RJ, Wasserman PG, Crothers BA, Clayton AC, Henry MR, Chmara BA, Clary KM, Fraig MM, Moriarty AT: Do liquid-based preparations of urinary cytology perform differently than classically prepared cases? Observations from the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology. Arch Pathol Lab Med; 2010 Jan;134(1):19-22
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  • OBJECTIVES: To compare the performance of liquid-based preparation specimens to classically prepared urine specimens with a malignant diagnosis in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology.
  • DESIGN: Participant responses between 2000 and 2007 for urine specimens with a reference diagnosis of high-grade urothelial carcinoma/carcinoma in situ/dysplasia (HGUCA), squamous cell carcinoma, or adenocarcinoma were evaluated.
  • These results were statistically different for the exact reference interpretation of HGUCA (P < .001) but not for adenocarcinoma (P = .22).
  • Cytotechnologists demonstrate statistically better performance for the general category of "positive-malignant" compared with pathologists for all urinary slide types and for the exact reference interpretation of HGUCA (94% versus 91.1%; P < .001) but not adenocarcinoma (96.3% versus 95.8%; P = .77) or squamous cell carcinoma (93.6% versus 87.7%; P = .07).
  • The liquid-based preparation challenges also performed better for the exact reference interpretation of HGUCA, but no difference was observed for adenocarcinoma challenges.
  • These results suggest that liquid-based preparations facilitate a more accurate diagnosis than conventional preparations.
  • [MeSH-major] Cytological Techniques / methods. Pathology, Clinical / methods. Urinary Bladder Neoplasms / diagnosis. Urine / cytology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Adenocarcinoma / urine. Carcinoma in Situ / diagnosis. Carcinoma in Situ / pathology. Carcinoma in Situ / urine. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / urine. Diagnosis, Differential. Humans. Societies, Medical. United States

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  • (PMID = 20073599.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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63. Izzo JG, Luthra R, Wu TT, Correa AM, Luthra M, Anandasabapathy S, Chao KS, Hung MC, Aggarwal B, Hittelman WN, Ajani JA: Molecular mechanisms in Barrett's metaplasia and its progression. Semin Oncol; 2007 Apr;34(2 Suppl 1):S2-6
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  • The dramatic increase in the incidence and poor overall survival rates of esophageal/gastroesophageal junction adenocarcinoma underscore the necessity to discover molecular markers that can be used for risk assessment, early diagnosis, and targeted therapeutic intervention.
  • Barrett's esophagus (BE) is proposed to represent a precursor of esophageal/gastroesophageal junction adenocarcinoma.
  • Using a combination of in situ tissue-based and high-throughput analyses, we investigated alterations of cell-cycle regulators and inflammation-associated molecular effectors.
  • [MeSH-minor] Adenocarcinoma / pathology. Cell Transformation, Neoplastic / pathology. Chemoprevention. Cyclin D1 / physiology. Disease Progression. Early Diagnosis. Humans. Metaplasia. NF-kappa B / physiology. Risk Assessment. Signal Transduction / physiology. Treatment Outcome

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  • (PMID = 17449347.001).
  • [ISSN] 0093-7754
  • [Journal-full-title] Seminars in oncology
  • [ISO-abbreviation] Semin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 86390; United States / NIDCR NIH HHS / DE / R01 DE 13157-04
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / NF-kappa B; 136601-57-5 / Cyclin D1
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64. Geldenhuys L, Murray ML: Sensitivity and specificity of the Pap smear for glandular lesions of the cervix and endometrium. Acta Cytol; 2007 Jan-Feb;51(1):47-50
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  • OBJECTIVE: To investigate the sensitivity and specificity of the Pap smear for detection of adenocarcinoma in situ of the cervix (AIS), endocervical adenocarcinoma (ECAC) and endometrial adenocarcinoma (EAC) as well as the overall specificity of the smear for detection of glandular lesions in general.
  • STUDY DESIGN: Computer records of the laboratory of the QE II Health Sciences Center, Halifax, were searched for patients who had AIS, ECAC or EAC diagnosed on histology between June 1, 1999, and May 31, 2001 and who had had a Pap smear within the preceding year.
  • Computer records were also searched for patients who had a Pap smear result consisting of suspicious or positive for AIS or adenocarcinoma (AC) with subsequent tissue diagnosis during the same time.
  • RESULTS: One hundred percent of patients with AIS, 80% with ECAC and 22% with EAC on histology had positive findings on a Pap smear performed within a year of the histologic diagnosis.
  • One hundred percent of patients with a Pap smear result consisting of suspicious or positive for AIS or AC and follow-up histology had a lesion on histology: 13% AIS, 13% ECAC, 37% EAC, 23% other AC, 10% high grade squamous lesion and 0.3% low grade squamous lesion.
  • [MeSH-major] Adenocarcinoma / diagnosis. Endometrial Neoplasms / diagnosis. Papanicolaou Test. Uterine Cervical Neoplasms / diagnosis. Vaginal Smears
  • [MeSH-minor] Carcinoma in Situ. Cervical Intraepithelial Neoplasia / diagnosis. Female. Humans. Sensitivity and Specificity. Uterine Hemorrhage / diagnosis


65. Sláma J, Freitag P, Cibula D, Fischerová D, Janousek M, Pavlista D, Strunová M, Zikán M, Jancárková N: [Glandular premalignant lesions of the uterine cervix]. Ceska Gynekol; 2006 Dec;71(6):446-50
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  • RESULTS: The incidence of invasive adenocarcinomas of the uterine cervix is increasing.
  • Incidence ratio between adenocarcinomas and spinocellular carcinomas is approximately 1:5; however ratio of premalignant lesions reaches only about 1:80.
  • Glandular premalignant disease is usually found in the specimen taken for squamous disease.
  • PAP-smear of AGC-NOS/-NEO or adenocarcinoma in situ (AIS) in combination with typical colposcopic appearance raise a suspicion of glandular lesion.
  • Direct biopsy must be always performed to get definite diagnosis.
  • CONCLUSION: Diagnosis of glandular premalignat lesion of the uterine cervix is more complicated in comparison to spinocellular one, however it is getting more significant due to increasing incidence.


66. Francis WP, Rodrigues DM, Perez NE, Lonardo F, Weaver D, Webber JD: Prophylactic laparoscopic-assisted total gastrectomy for hereditary diffuse gastric cancer. JSLS; 2007 Jan-Mar;11(1):142-7
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  • Loss of this important structure can result in hereditary diffuse gastric cancer (HDGC), which carries a high mortality if early diagnosis is not made.
  • On histologic examination, however, the stomach was found to have diffuse (signet ring cell) adenocarcinoma in-situ with 11 microscopic foci of invasive adenocarcinoma limited to the lamina propria.
  • Endoscopic screening in HDGC cannot rule out diffuse GC, because the stomach and biopsies can be normal despite the presence of adenocarcinoma.


67. Gozzi G, Martinoli C, Conti GM, Ganzetti A, Bodini M, Fiorentino C, Marini UP, Santini D, Bacigalupo L: Screening mammography interpretation test: more frequent mistakes. Radiol Med; 2005 Mar;109(3):268-79
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  • As regards the 23 most frequently misread cases, these were 10/32 (31.25%) mammograms positive for malignancy and 13/128 (10.15%) negative mammograms or mammograms showing benign disease.
  • The 10 malignancies included 7 infiltrating ductal carcinomas, 1 infiltrating cribriform carcinoma, 1 infiltrating tubular carcinoma, and 1 carcinoma in situ.
  • The 13 cases of benign disease--as established by histology or long-term follow-up--mistaken for malignancies by the test participants were fibrocystic breast disease in 5 cases, surgical scar in 1 case, ABBI scar in 1 case, radial scar in 2 cases, microcalcifications that had remained stable for years in 2 cases, focal sclero-adenosis in 1 case and sclero-elastosis in 1 case.
  • CONCLUSIONS: The errors were due to microcalcifications, benign disease simulating a neoplasm, overlapping tissue, visibility of a lesion in one projection only, lesion site in relation to the corpus mammae, missed areas of asymmetry.
  • Attention must be paid to these signs of focal breast disease since, if correctly evaluated, they enable the early diagnosis of low-grade carcinomas that frequently carry a favourable prognosis.
  • [MeSH-minor] Adenocarcinoma / radiography. Breast Diseases / surgery. Calcinosis / radiography. Carcinoma in Situ / radiography. Carcinoma, Ductal, Breast / radiography. Cicatrix / surgery. False Negative Reactions. False Positive Reactions. Female. Fibrocystic Breast Disease / radiography. Follow-Up Studies. Humans. Observer Variation


68. Adsay NV: Cystic neoplasia of the pancreas: pathology and biology. J Gastrointest Surg; 2008 Mar;12(3):401-4
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  • In contrast with solid tumors, most of which are invasive ductal adenocarcinoma with dismal prognosis, cystic lesions of the pancreas are often either benign or low-grade indolent neoplasia.
  • While many are innocuous adenomas--in particular, those that are small and less complex, and in the case of IPMN, those that are branch-duct type are more commonly benign, some harbor or progress into in situ or invasive carcinomas.
  • The presence of ovarian-type stroma has now almost become a requirement for the diagnosis of MCN, and when defined as such, MCN is seen almost exclusively in women of perimenopausal age group as thick-walled multilocular cystic mass in the tail of the pancreas in contrast with IPMN which afflicts an elder population, both genders in almost equal numbers, and occur predominantly in the head of the organ.
  • In contrast, the rare cystic tumors that occur as a result of degenerative/necrotic changes in otherwise solid neoplasia such as the rare cystic ductal adenocarcinomas, cystic endocrine neoplasia, and most importantly, solid-pseudopapillary tumor (SPT) in which cystic change is so common that it used to be incorporated into its name ("solid-cystic," "papillary-cystic") are malignant neoplasia, albeit variable degrees of aggressiveness.
  • [MeSH-major] Adenoma / pathology. Carcinoma in Situ / pathology. Neoplasms, Cystic, Mucinous, and Serous / pathology. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology. Precancerous Conditions / pathology
  • [MeSH-minor] Adenocarcinoma, Mucinous / mortality. Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology. Carcinoma, Papillary / mortality. Carcinoma, Papillary / pathology. Cystadenoma / pathology. Cystadenoma, Serous / pathology. Dilatation, Pathologic. Humans. Necrosis

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  • [Cites] Am J Surg Pathol. 2004 Aug;28(8):977-87 [15252303.001]
  • [Cites] Am J Surg Pathol. 1989 Jan;13(1):61-6 [2909198.001]
  • [Cites] Ann Surg. 2004 Jun;239(6):788-97; discussion 797-9 [15166958.001]
  • [Cites] Semin Diagn Pathol. 2000 Feb;17(1):81-8 [10721809.001]
  • [Cites] Br J Surg. 2003 Oct;90(10):1244-9 [14515294.001]
  • [Cites] Pancreatology. 2006;6(1-2):17-32 [16327281.001]
  • [Cites] Semin Diagn Pathol. 2000 Feb;17(1):43-55 [10721806.001]
  • [Cites] Am J Surg Pathol. 1999 Apr;23 (4):410-22 [10199470.001]
  • [Cites] J Gastrointest Surg. 2003 Mar-Apr;7(3):417-28 [12654569.001]
  • [Cites] Virchows Arch. 2004 Aug;445(2):168-78 [15185076.001]
  • [Cites] Semin Diagn Pathol. 2000 Feb;17(1):56-65 [10721807.001]
  • [Cites] Am J Surg Pathol. 2004 Jul;28(7):839-48 [15223952.001]
  • [Cites] Am J Surg Pathol. 2000 Oct;24(10):1372-7 [11023098.001]
  • [Cites] Am J Surg Pathol. 1999 Jan;23 (1):1-16 [9888699.001]
  • [Cites] Semin Diagn Pathol. 2000 Feb;17(1):66-80 [10721808.001]
  • [Cites] Mod Pathol. 2007 Feb;20 Suppl 1:S71-93 [17486054.001]
  • [Cites] World J Surg. 2003 Mar;27(3):319-23 [12607059.001]
  • [Cites] Am J Surg Pathol. 2001 Jan;25(1):26-42 [11145249.001]
  • [Cites] Am J Clin Pathol. 1978 Mar;69(3):289-98 [637043.001]
  • (PMID = 17957438.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 19
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69. Kałuzyński A, Olszak A, Smolarz B, Kowalczyk A, Kulig A: [Cervical glandular intraepithelial neoplasia topography and the risk of conisation]. Ginekol Pol; 2005 Oct;76(10):763-9
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  • [Title] [Cervical glandular intraepithelial neoplasia topography and the risk of conisation].
  • OBJECTIVES: The frequency of endocervical adenocarcinoma is increasing in comparison with squamous cell carcinoma and it presents a very difficult diagnostic and therapeutic problem.
  • 1) Evaluation of topography of the cervical glandular intraepithelial neoplasia (CGIN) 2) An analysis of the Human Papillomavirus (HPV) infection rate in samples.
  • MATERIALS AND METHODS: 360 amputated uterine cervix samples with histologically-proven diagnosis of cervical intraepithelial neoplasia (CIN-3) were evaluated.
  • RESULTS: Among 360 positive cervical intraepithelial glandular neoplasia samples (CIN-3) 71 (19.7%) showed coexisting glandular lesions (CGIN-1, 2, 3).
  • CIN-3 is associated in about 20% with cervical glandular intraepithelial neoplasia (CGIN).
  • [MeSH-major] Cervical Intraepithelial Neoplasia / pathology. Conization. Papillomavirus Infections / pathology. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Carcinoma in Situ / pathology. Female. Humans. Papillomaviridae / isolation & purification. Polymerase Chain Reaction. Precancerous Conditions / pathology. Retrospective Studies


70. Louie LD, Crowe JP, Dawson AE, Lee KB, Baynes DL, Dowdy T, Kim JA: Identification of breast cancer in patients with pathologic nipple discharge: does ductoscopy predict malignancy? Am J Surg; 2006 Oct;192(4):530-3
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  • OBJECTIVE: The purpose of the current study was to review characteristics of patients with nipple discharge who underwent ductoscopy-assisted excisional biopsy who had a final diagnosis of carcinoma.
  • METHODS: A retrospective review was performed of patients presenting with pathologic nipple discharge (PND) who underwent ductoscopy-assisted excisional biopsy and had a final diagnosis of carcinoma.
  • RESULTS: A total of 14 (7%) of 188 patients who underwent ductoscopy-assisted excision had a final pathology of ductal carcinoma-in-situ (DCIS) (12/14, 86%) or invasive breast cancer with DCIS (2/14, 14%).
  • There were no visual abnormalities noted during ductoscopy that accurately predicted a final diagnosis of malignancy.
  • CONCLUSIONS: Although occult malignancies can be identified in patients undergoing ductoscopy-assisted biopsy for PND, no clear morphologic changes visualized during ductoscopy definitively indicated the presence of malignancy.
  • [MeSH-major] Adenocarcinoma / pathology. Breast Neoplasms / pathology. Endoscopy. Exudates and Transudates / secretion. Mammary Glands, Human / pathology. Nipples / secretion

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  • (PMID = 16978968.001).
  • [ISSN] 0002-9610
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Dalrymple C, Valmadre S, Cook A, Atkinson K, Carter J, Houghton CR, Russell P: Cold knife versus laser cone biopsy for adenocarcinoma in situ of the cervix--a comparison of management and outcome. Int J Gynecol Cancer; 2008 Jan-Feb;18(1):116-20
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  • [Title] Cold knife versus laser cone biopsy for adenocarcinoma in situ of the cervix--a comparison of management and outcome.
  • Eighty-two patients with adenocarcinoma in situ of the cervix managed at Royal Prince Alfred Hospital were reviewed and data were collected on those treated by cold knife cone biopsy (n= 38) and laser cone biopsy (n= 44).
  • Invasive disease was found in 24 patients, 16 of whom were managed conservatively with good outcome.
  • In those patients from both groups managed conservatively, there was only one recurrence, squamous preinvasive disease after 8 years.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma in Situ / surgery. Conization / methods. Laser Therapy. Uterine Cervical Neoplasms / surgery

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  • (PMID = 17506846.001).
  • [ISSN] 1525-1438
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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72. Schnatz PF, Sharpless KE, O'Sullivan DM: Use of human papillomavirus testing in the management of atypical glandular cells. J Low Genit Tract Dis; 2009 Apr;13(2):94-101
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  • Atypical glandular cell-associated disease included cervical intraepithelial neoplasia 2 (CIN 2) or anything of greater pathologic importance on histology.
  • Human papillomavirus-associated disease included CIN 2-3, glandular atypia, adenocarcinoma in situ, or any cervical malignancy.
  • RESULTS: Two hundred fourteen cases of AGC with concurrent HPV testing were evaluated, including 27 cases of AGC with concurrent atypical squamous cells, low-grade squamous intraepithelial lesions, or high-grade squamous intraepithelial lesions.
  • The rate of disease was 20.6%, with a 7.0% prevalence of cancer.
  • The rate of HPV-associated disease among cases testing positive for HPV was 40.0% compared with 4.0% among HPV-negative cases.
  • The sensitivity of HPV testing for HPV-associated disease was 81.3%.
  • Women positive for human papillomavirus were less likely to have endometrial or extrauterine disease (1.5%) than HPV-negative women (7.4%).
  • Women positive for human papillomavirus are at higher risk than HPV-negative women for cervical disease and should be evaluated and followed up closely.
  • [MeSH-major] Cervical Intraepithelial Neoplasia / virology. DNA, Viral / isolation & purification. Papillomaviridae / isolation & purification. Papillomavirus Infections / diagnosis. Uterine Cervical Dysplasia / virology. Uterine Cervical Neoplasms / virology


73. DeSimone CP, Day ME, Tovar MM, Dietrich CS 3rd, Eastham ML, Modesitt SC: Rate of pathology from atypical glandular cell Pap tests classified by the Bethesda 2001 nomenclature. Obstet Gynecol; 2006 Jun;107(6):1285-91
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  • Seventeen women (21%) had preinvasive disease: cervical intraepithelial neoplasia 2 or 3, adenocarcinoma in situ and endometrial hyperplasia, whereas 14 women (17%) had invasive adenocarcinomas of the endometrium, cervix, ovary, and rectum.
  • Specifically, they were more likely to have preinvasive disease and less likely to have invasive carcinoma.
  • CONCLUSION: Atypical glandular cell cytology confers a risk (38%) of either preinvasive disease or carcinoma, with the risk of carcinoma increasing significantly for women aged older than 40.
  • [MeSH-major] Cervical Intraepithelial Neoplasia / epidemiology. Uterine Cervical Dysplasia / epidemiology. Uterine Cervical Neoplasms / epidemiology. Vaginal Smears / classification
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adolescent. Adult. Aged. Aged, 80 and over. Colposcopy. Electrosurgery / statistics & numerical data. Female. Genital Neoplasms, Female / epidemiology. Health Planning Guidelines. Humans. Middle Aged. Practice Guidelines as Topic


74. Smedts F, Ramaekers FC, Hopman AH: The two faces of cervical adenocarcinoma in situ. Int J Gynecol Pathol; 2010 Jul;29(4):378-85
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  • [Title] The two faces of cervical adenocarcinoma in situ.
  • In order of frequency, cervical intraepithelial neoplasia (CIN), combined adenocarcinoma in situ (AIS)/CIN lesions, and solitary AIS are the most prevalent premalignant lesions of the uterine cervix.
  • As the morphologic distinction of these subtypes is not always straightforward, we performed an immunophenotyping analysis to establish distinguishing profiles for each of these squamous and glandular progenitor lesions of cervical carcinoma.
  • A series of 26 premalignant cervical lesions, comprising 13 cases of AIS, of which 7 represented solitary AIS and 6 were combined with CIN (combined AIS/CIN), as well as 13 solitary high-grade CIN lesions, were immunophenotypically analyzed using antibodies directed against p16, p63, bcl-2, and cytokeratins (CK) 5, 7, 8, 13, 17, 18, and 19.
  • Combined AIS/CIN lesions also expressed the full complement of markers in both the AIS and CIN compartments.
  • However, the expression of p63, bcl-2, CK5, and CK17 was lower in AIS compared with CIN.
  • The solitary AIS lesions could be subdivided into 2 subgroups, 1 expressing the full complement of markers and a second group in which no expression of p63, bcl-2, CK5, and a sporadically CK17 expression was observed.
  • We conclude that 2 phenotypically distinct types of AIS can be identified, that is, AIS with a reserve cell marker phenotype and AIS with an endocervical glandular phenotype.
  • These observations support the view that reserve cells are capable of bidirectional premalignant transformation, that is, into CIN and reserve cell-type AIS, as well as combined AIS/CIN.
  • The endocervical type of AIS is probably a result of the unidirectional transformation of progenitor cells within the glandular cell compartment.
  • [MeSH-major] Adenocarcinoma / pathology. Biomarkers, Tumor / metabolism. Cervical Intraepithelial Neoplasia / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 20567153.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Tumor Suppressor Proteins; 68238-35-7 / Keratins
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75. Ding HY, Yang GZ: [Clinicopathological features of the mucocele-like lesions in the breast]. Zhonghua Bing Li Xue Za Zhi; 2008 Jan;37(1):31-4
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  • METHODS: Nine cases of mucocele-like lesions in the breast were reported for the morphological and immunohistochemical features, the differential diagnosis, and a literature review.
  • CONCLUSION: Mucocele-like lesions of the breast is a group of mostly benign disease, and the differential diagnosis should include mucinous carcinoma.
  • [MeSH-major] Breast / pathology. Breast Neoplasms / pathology. Carcinoma, Ductal, Breast / pathology. Diagnosis, Differential. Hyperplasia / pathology. Mucocele / pathology
  • [MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / pathology. Carcinoma in Situ / diagnosis. Female. Gene Expression Regulation, Neoplastic / physiology. Humans. Intestinal Neoplasms / pathology

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  • (PMID = 18509982.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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76. Chung JH, Choe G, Jheon S, Sung SW, Kim TJ, Lee KW, Lee JH, Lee CT: Epidermal growth factor receptor mutation and pathologic-radiologic correlation between multiple lung nodules with ground-glass opacity differentiates multicentric origin from intrapulmonary spread. J Thorac Oncol; 2009 Dec;4(12):1490-5
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  • This series included 18 atypical adenomatous hyperplasias (AAH), 15 bronchioloalveolar carcinomas (BAC), and 23 adenocarcinomas (ADC) obtained from 24 patients.
  • The pure GGO appearance in the radiologic examination corresponded preinvasive pathologic change.
  • [MeSH-major] Adenocarcinoma, Bronchiolo-Alveolar / pathology. Carcinoma in Situ / pathology. Hyperplasia / pathology. Lung Neoplasms / pathology. Mutation / genetics. Precancerous Conditions / pathology. Receptor, Epidermal Growth Factor / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / genetics. DNA, Neoplasm / genetics. Diagnosis, Differential. Female. Genotype. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Polymerase Chain Reaction. Prognosis. Proto-Oncogene Proteins / blood. Proto-Oncogene Proteins / genetics. Tomography, X-Ray Computed. ras Proteins / blood. ras Proteins / genetics

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  • (PMID = 19844187.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / KRAS protein, human; 0 / Proto-Oncogene Proteins; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 3.6.5.2 / ras Proteins
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77. Negri G, Romano F, Vittadello F, Kasal A, Mazzoleni G, Colombetti V, Egarter-Vigl E: Laminin-5 gamma2 chain immunohistochemistry facilitates the assessment of invasiveness and improves the diagnostic reproducibility of glandular lesions of the cervix uteri. Hum Pathol; 2006 Jun;37(6):704-10
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  • The aim of this study was to evaluate the influence of laminin-5 (LN-5) gamma2 chain immunohistochemistry on the assessment of invasiveness in cervical adenocarcinomas and its impact on the diagnostic reproducibility of glandular lesions of the cervix uteri.
  • Immunohistochemistry with LN-5 gamma2 was performed on 30 cases, including 12 adenocarcinomas in situ (AISs), 5 AISs that were suggestive, albeit not conclusive, of infiltration (AIS+), 7 frankly invasive adenocarcinomas, and 6 nonneoplastic cases with reactive changes.
  • Laminin-5 gamma2 was expressed in 5 of the 12 AISs (41.6%), all AIS+ and invasive adenocarcinomas, and none of the reactive cases.
  • Cytoplasmatic staining was detected at the invasion front of frankly invasive adenocarcinomas and in tumor buds of all AISs with minimal stromal infiltration.
  • The difference in interobserver agreement further increased when including only AISs and AIS+ in the analysis (0.17 versus 0.72; P = .000).
  • After immunohistochemical evaluation, the original AIS diagnosis was unanimously changed to adenocarcinoma with minimal stromal invasion in 3 of 12 cases (25%), whereas a discordant hematoxylin-eosin diagnosis turned into a concordant one in 10 of 13 cases (6 AISs, 2 AIS+, 2 adenocarcinomas; 76.9%).
  • Immunohistochemistry with LN-5 gamma2 facilitates the assessment of the invasiveness of cervical adenocarcinomas and improves the interobserver agreement in glandular lesions of the cervix uteri.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Cell Adhesion Molecules / analysis. Uterine Cervical Neoplasms / metabolism. Uterine Cervical Neoplasms / pathology


78. Athanassiadou P, Grapsa D: Value of endoscopic retrograde cholangiopancreatography-guided brushings in preoperative assessment of pancreaticobiliary strictures: what's new? Acta Cytol; 2008 Jan-Feb;52(1):24-34
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  • Various factors seem to influence the accuracy of cytologic diagnosis and are attributed to sampling, technical and interpretation errors.
  • Ancillary methods, such as immunocytochemistry, flow cytometry, image analysis, fluorescence in situ hybridization (FISH) and the newly discovered method of global analysis of gene expression are helpful in resolving cases with inconclusive cytology and are vigorously investigated for their value in assessing the expression of novel tumor markers for the diagnosis and prognosis of pancreatic and bile duct carcinomas.
  • To increase the sensitivity of brush cytology and strengthen its role in the preoperative assessment of patients with pancreaticobiliary malignancies, the following are of the utmost importance: improvement of current sampling and cytopreparation techniques, introduction of a uniform system for reporting epithelial abnormalities based on strict and clearly distinct morphologic criteria for each pathologic entity and incorporation of experience and knowledge derived from standard cytologic methods and novel diagnostic technologies in clinical practice without compromising the high specificity associated with brush cytology.
  • [MeSH-major] Adenocarcinoma / diagnosis. Bile Ducts / pathology. Biliary Tract Neoplasms / diagnosis. Cholangiopancreatography, Endoscopic Retrograde / methods. Pancreatic Ducts / pathology. Pancreatic Neoplasms / diagnosis

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  • (PMID = 18323272.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 119
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79. Sato T, Muto I, Fushiki M, Hasegawa M, Hasegawa M, Sakai T, Sekiya M: Metastatic breast cancer from gastric and ovarian cancer, mimicking inflammatory breast cancer: report of two cases. Breast Cancer; 2008;15(4):315-20
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  • Both patients, who had prior advanced malignant disease, presented with unilateral breast redness and swelling with peau d'orange sign, resembling primary inflammatory breast cancer or acute mastitis.
  • Breast biopsy revealed poorly differentiated adenocarcinoma with signet-ring cells or clear cell carcinoma in the lymphatic vessels and the parenchyma without an in situ lesion, similar to primary lesions of the stomach or ovary, respectively.
  • Immunohistochemical staining for estrogen receptor, progesterone receptor, and gross cystic disease fluid protein 15 was of value for correct diagnosis.
  • Since breast metastasis is a sign of poor prognosis of the primary malignant disease, the possibility of breast metastasis should be considered in appropriate patients to preclude unnecessary major surgery.
  • [MeSH-major] Adenocarcinoma / secondary. Breast Neoplasms / secondary. Ovarian Neoplasms / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma, Clear Cell / secondary. Adenocarcinoma, Clear Cell / therapy. Aged. Diagnosis, Differential. Female. Humans. Middle Aged. Tomography, X-Ray Computed


80. Nara M, Hashi A, Murata S, Kondo T, Yuminamochi T, Nakazawa K, Katoh R, Hoshi K: Lobular endocervical glandular hyperplasia as a presumed precursor of cervical adenocarcinoma independent of human papillomavirus infection. Gynecol Oncol; 2007 Aug;106(2):289-98
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  • [Title] Lobular endocervical glandular hyperplasia as a presumed precursor of cervical adenocarcinoma independent of human papillomavirus infection.
  • OBJECTIVES: The aim of this study was to investigate differences in the process of carcinogenesis between adenocarcinoma coexistent with LEGH and conventional adenocarcinoma.
  • METHODS: Using the surgical pathology files of patients who visited the University of Yamanashi Hospital, Yamanashi Central Hospital and Kofu Municipal Hospital between 1996 and 2005, pathological diagnoses were reevaluated based on criteria for the diagnosis of LEGH by Nucci et al.
  • As for the cases including adenocarcinoma with LEGH: (a) we created a map showing position of the LEGH component and adenocarcinoma component and squamo-columnar junction (SCJ) in HE-stained specimens, (b) immunohistochemical staining was performed using antibodies to CEA, HIK1083 and p53, and (c) detection of HPV DNA was performed using PCR and in situ hybridization (ISH).
  • RESULTS: Endocervical adenocarcinoma was observed coexistent with LEGH in 5 cases (19.2%). (a) LEGH was located in a remote place from the SCJ.
  • Sizes of lesions in the 5 cases ranged from 18 to 35 mm in width and 7 to 16 mm in depth. (b) HIK1083 was diffusely immunopositive in the cytoplasm of LEGH component and focal immunopositive in 4 cases with adenocarcinoma component.
  • Immunopositivity for CEA was seen in the cytoplasm of adenocarcinoma component in 4 cases.
  • Immunopositivity for p53 was seen in adenocarcinoma component nuclei in 2 cases. (c) HPV DNA was not detected using PCR and ISH in either LEGH or adenocarcinoma components.
  • CONCLUSIONS: The present study suggests that clear differences exist in the process of carcinogenesis between adenocarcinoma associated with LEGH and conventional adenocarcinoma.
  • LEGH may represent a precursor of cervical adenocarcinoma independent of HPV infection.
  • As LEGH displays characteristics of precancerous mucinous adenocarcinoma, surgical treatment should be considered for LEGH growing beyond a certain size.
  • [MeSH-major] Adenocarcinoma / pathology. Cervix Uteri / pathology. Neoplasms, Glandular and Epithelial / pathology. Precancerous Conditions / pathology. Uterine Cervical Neoplasms / pathology


81. Cora T, Acar H, Ceran S, Bodur S: Analysis of chromosomes 9 and 11 aneuploidy frequency in pleural effusion of patients with and without malignancy: interphase FISH technique. Cancer Biol Ther; 2005 Feb;4(2):248-51
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  • Diagnosis of effusion from the patients is frequently troublesome for the cytologist because of the differentiation and biological behavior of different cells type in effusion.
  • In the present study, chromosomal aneuploidy status in effusion cells derived from 32 patients including 14 patients with non-malignant and 18 patients with malignant diseases [including malign mesothelioma (n = 6), adeno carcinoma (n = 10), small cell carcinoma (n = 2)] was analyzed by using fluorescence in situ hybridization (FISH) with centromere specific probes for chromosomes 9 and 11.
  • However, aneuploidies of chromosomes 9 and 11 in effusion cells from patients with malignant disease had significantly higher than in effusion cells from patients with non-malignant (P = 0.000), suggesting that chromosomes 9 and 11 are frequently involved in the status of disease.
  • [MeSH-minor] Adenocarcinoma / genetics. Adenocarcinoma / pathology. Aneuploidy. Carcinoma, Small Cell / genetics. Carcinoma, Small Cell / pathology. Case-Control Studies. Centromere. Chromosome Mapping. Female. Humans. In Situ Hybridization, Fluorescence / methods. Interphase. Male. Mesothelioma / genetics. Mesothelioma / pathology

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  • (PMID = 15753650.001).
  • [ISSN] 1538-4047
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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82. Sanati S, Huettner P, Ylagan LR: Role of ProExC: a novel immunoperoxidase marker in the evaluation of dysplastic squamous and glandular lesions in cervical specimens. Int J Gynecol Pathol; 2010 Jan;29(1):79-87
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  • Nine low-grade squamous intraepithelial lesion, 35 high-grade squamous intraepithelial lesion, 23 squamous metaplasia, and 14 adenocarcinoma in situ specimens were retrieved from our hospital files.
  • ProExC had sensitivity, specificity, and positive and negative predictive value of 89%, 100%, 100%, and 82%, respectively, for distinguishing high-grade squamous intraepithelial lesion from squamous metaplasia, and 93%, 100%, 100%, and 98%, respectively, for distinguishing adenocarcinoma in situ from reactive benign endocervix.
  • ProExC may eventually be used in conjunction with morphologic and human papillomavirus evaluation for better classification of indeterminate cervical lesions in Papanicolaou smears.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cervical Intraepithelial Neoplasia / diagnosis. Immunoenzyme Techniques. Uterine Cervical Dysplasia / diagnosis. Uterine Cervical Neoplasms / diagnosis

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  • (PMID = 19952938.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Cell Cycle Proteins; 0 / DNA-Binding Proteins; 0 / Nuclear Proteins; EC 3.6.4.12 / MCM2 protein, human; EC 3.6.4.12 / Minichromosome Maintenance Complex Component 2; EC 5.99.1.3 / DNA Topoisomerases, Type II; EC 5.99.1.3 / DNA topoisomerase II alpha
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83. Zhao C, Florea A, Austin RM: Clinical utility of adjunctive high-risk human papillomavirus DNA testing in women with Papanicolaou test findings of atypical glandular cells. Arch Pathol Lab Med; 2010 Jan;134(1):103-8
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  • Among the 75 cases with hrHPV+ AGC results, 13 (17.3%) had cervical intraepithelial neoplasia grades 2/3, 10 (13.3%) had adenocarcinoma in situ, and 3 (4.0%) had cervical invasive adenocarcinoma, whereas for 234 women with hrHPV(-) results, 1 (0.4%) had cervical intraepithelial neoplasia grades 2/3, 1 (0.4%) had adenocarcinoma in situ, 1 each (0.4%) had cervical adenocarcinoma and ovarian carcinoma, and 8 (3.4%) had endometrial carcinoma.
  • CONCLUSIONS: Positive hrHPV AGC results were most strongly associated with cervical intraepithelial neoplasia grades 2/3 and adenocarcinoma in situ in women younger than 50 years.
  • Positive hrHPV AGC results were also present in all 3 cases of invasive cervical adenocarcinoma in women younger than 50 years.
  • Of note, hrHPV(-) AGC results were present in 10 of 13 carcinomas (76.9%) detected after AGC Pap tests, all in women 40 years or older with endometrial adenocarcinomas (n = 8), ovarian carcinoma (n = 1), and cervical adenosquamous carcinoma in a woman (n = 1) in her 50s.
  • Testing for hrHPV after AGC Pap testing was most helpful in the detection of cervical intraepithelial neoplasia grades 2/3, adenocarcinoma in situ, and invasive cervical adenocarcinomas in women younger than 50 years.
  • [MeSH-major] Adenocarcinoma / pathology. Cervical Intraepithelial Neoplasia / pathology. DNA, Viral. Papanicolaou Test. Papillomaviridae / genetics. Uterine Cervical Neoplasms / pathology. Vaginal Smears
  • [MeSH-minor] Adult. Age Factors. Aged. Aged, 80 and over. Carcinoma in Situ / pathology. Carcinoma in Situ / virology. Endometrial Neoplasms / pathology. Endometrial Neoplasms / virology. Female. Humans. Middle Aged. Ovarian Neoplasms / pathology. Ovarian Neoplasms / virology. Retrospective Studies. Risk Factors. Sensitivity and Specificity. Young Adult


84. Goodman MT, Tung KH, Wilkens LR: Comparative epidemiology of breast cancer among men and women in the US, 1996 to 2000. Cancer Causes Control; 2006 Mar;17(2):127-36
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  • The incidence of lobular cancer was rare in men, but Paget's disease and papillary carcinoma occurred with lower relative frequency in women than in men.
  • In situ breast cancer was diagnosed in 10.8% of men and 16.2% of women.
  • Localized breast cancer was the most common stage at diagnosis in both sexes and all ethnic groups, although women were more likely than men to be diagnosed at a localized stage.
  • [MeSH-major] Adenocarcinoma / epidemiology. Breast Neoplasms / epidemiology. Registries

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  • (PMID = 16425090.001).
  • [ISSN] 0957-5243
  • [Journal-full-title] Cancer causes & control : CCC
  • [ISO-abbreviation] Cancer Causes Control
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CN / N01-CN-67001; United States / PHS HHS / / U75/CCU515998
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Netherlands
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85. Wang QX, Wang SZ, Liu J: [Clinical significance on atypical cervical glandular cytology]. Zhonghua Yi Xue Za Zhi; 2009 Oct 27;89(39):2779-82
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  • Sixteen patients with AGC as "favor intraepithelial neoplasia" were of 9 pathological abnormalities.
  • Ten patients with AGC as "adenocarcinoma in situ" or "adenocarcinoma" were of 6 pathological abnormalities. (3) 100% of patients with AGC had both of colposcopic and cytologic follow-ups: 1 case CIN1, 1 case CIN2 and 1 case CIN3. (4) One of 10 patients was younger than 35 years old with CGIN1 and the other 9 patient aged over 35 years old had a greater diversity of glandular lesions.
  • CONCLUSION: A finding of AGC requires both colposcopy and an aggressive workup because of a high rate of cancer and precancerous lesions.
  • The onset of disease is age-related.
  • Women aged over 35 years old has a greater diversity of glandular lesions and account for most cases of cervical and endometrial adenocarcinoma.
  • [MeSH-major] Cervical Intraepithelial Neoplasia / pathology. Cervix Uteri / cytology. Cervix Uteri / pathology. Uterine Cervical Neoplasms / pathology


86. Lee KM, Cao D, Itami A, Pour PM, Hruban RH, Maitra A, Ouellette MM: Class III beta-tubulin, a marker of resistance to paclitaxel, is overexpressed in pancreatic ductal adenocarcinoma and intraepithelial neoplasia. Histopathology; 2007 Oct;51(4):539-46
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  • [Title] Class III beta-tubulin, a marker of resistance to paclitaxel, is overexpressed in pancreatic ductal adenocarcinoma and intraepithelial neoplasia.
  • Pancreatic ductal adenocarcinomas show limited responsiveness to taxanes, but little is known of the underlying mechanisms.
  • The aim of this study was to examine TUBB3 expression in pancreatic cancer cell lines, invasive pancreatic adenocarcinoma and pancreatic intraepithelial neoplasia (PanIN).
  • Immunohistochemistry was employed to assess TUBB3 in pancreatic cancer specimens, including 75 invasive adenocarcinomas and 41 PanIN precursor lesions.
  • In contrast, the vast majority (78-93%) of pancreatic ductal adenocarcinomas demonstrated either diffuse or focal TUBB3 expression.
  • CONCLUSIONS: TUBB3 is expressed in most pancreatic ductal adenocarcinomas, possibly accounting for the suboptimal response of these tumours to microtubule-stabilizing agents.
  • Up-regulation of TUBB3 in PanIN lesions suggests that microtubule dysfunction is an early feature of this disease.
  • [MeSH-major] Adenocarcinoma / metabolism. Antineoplastic Agents, Phytogenic / therapeutic use. Carcinoma in Situ / metabolism. Drug Resistance, Neoplasm. Paclitaxel / therapeutic use. Pancreatic Neoplasms / metabolism. Tubulin / metabolism

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  • (PMID = 17714470.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / U01 CA111294
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Biomarkers, Tumor; 0 / TUBB3 protein, human; 0 / Tubulin; P88XT4IS4D / Paclitaxel
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87. Hong L, Han Y, Zhang H, Li M, Gong T, Sun L, Wu K, Zhao Q, Fan D: The prognostic and chemotherapeutic value of miR-296 in esophageal squamous cell carcinoma. Ann Surg; 2010 Jun;251(6):1056-63
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  • A better understanding of changes in miRNA expression during esophageal carcinogenesis might lead to possible improvements in the diagnosis and treatment for esophageal carcinoma.
  • The expression of miR-296 was found increasingly up-regulated in esophagitis tissues, esophageal carcinoma in situ, and esophageal squamous cell cancer tissues.
  • Low expression of miR-296 was able to distinguish long-term survivors with node-positive disease from those dying within 20 months by predicting survival (median, 23.7 vs. 12.9 months).
  • [MeSH-minor] Adenocarcinoma / genetics. Adenocarcinoma / mortality. Adenocarcinoma / pathology. Animals. Apoptosis. Biomarkers, Tumor / analysis. Cell Proliferation. Down-Regulation. Drug Resistance, Neoplasm. Genes, cdc. Mice. Mice, Nude. Microarray Analysis. Prognosis. Survival Rate. Tumor Cells, Cultured


88. Ørbo A, Moe BT, Arnes M, Pettersen I, Larsen K, Eggen T, Myrmel K, Hanssen K: Prognostic markers for detection of coexistent carcinoma in high-risk endometrial hyperplasia. Anticancer Res; 2010 Nov;30(11):4649-55
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  • Thus, prediction of myoinvasive carcinoma by objective histomorphometry (4C-rule) and subjective diagnosis (endometrial intraepithelial neoplasia, EIN) were investigated in high-risk endometrial biopsies.
  • RESULTS: Myoinvasive disease was predicted with a sensitivity of 87% and a specificity of 79% by using 4C-rule assessment.
  • [MeSH-major] Adenocarcinoma / diagnosis. Biomarkers, Tumor. Carcinoma in Situ / diagnosis. Endometrial Hyperplasia / diagnosis. Endometrial Neoplasms / diagnosis. Precancerous Conditions / diagnosis

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  • (PMID = 21115919.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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89. Jayamohan Y, Karabakhtsian RG, Banks HW, Davey DD: Accuracy of Thinprep Imaging System in detecting atypical glandular cells. Diagn Cytopathol; 2009 Jul;37(7):479-82
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  • The aim of this study was to evaluate the accuracy of the ThinPrep Imaging System (Imager) in detecting atypical glandular cells (AGC) or adenocarcinoma in the 22 selected fields.
  • All cases reported as AGC or adenocarcinoma from January 2005 to December 2006 that had been initially screened by the Imager were retrospectively reviewed to determine whether the most diagnostically relevant groups/cells were within the 22 selected fields.
  • The cases were divided into two groups: the group with diagnostic cells detected within the 22 selected fields (accurately detected group) and the group with upgraded diagnosis following rescreening process (underdetected group).
  • The Imager accurately detected 32 (82%) of cases with abnormal glandular cells, including six cases reported as adenocarcinoma, one case as adenocarcinoma in situ (AIS), and 25 cases as AGC.
  • Among these, one case was adenocarcinoma, while the rest were reported as AGC.
  • Overall, the Imager was effective in detecting most AGC, AIS and invasive adenocarcinomas.
  • [MeSH-major] Adenocarcinoma / pathology. Image Processing, Computer-Assisted / methods. Uterine Neoplasms / pathology. Vaginal Smears / instrumentation. Vaginal Smears / methods

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  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 19185007.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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90. de Oliveira ER, Derchain SF, Sarian LO, Rabelo-Santos SH, Gontijo RC, Yoshida A, Andrade LA, Zeferino LC: Prediction of high-grade cervical disease with human papillomavirus detection in women with glandular and squamous cytologic abnormalities. Int J Gynecol Cancer; 2006 May-Jun;16(3):1055-62
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  • [Title] Prediction of high-grade cervical disease with human papillomavirus detection in women with glandular and squamous cytologic abnormalities.
  • The objective of this study was to assess whether human papillomavirus (HPV) detection with hybrid capture II (HC II) can help predict the presence and the nature, glandular or squamous, of histologic cervical lesions in women referred due to atypical glandular cells (AGC) or high-grade squamous intraepithelial lesion (HSIL).
  • Referral Pap smears comprised AGC (51 cases), AGC plus HSIL (28 cases), adenocarcinoma in situ (10 cases), and HSIL (158 cases).
  • [MeSH-minor] Adult. Carcinoma in Situ / diagnosis. Carcinoma in Situ / epidemiology. Carcinoma in Situ / virology. Cervical Intraepithelial Neoplasia / diagnosis. Cervical Intraepithelial Neoplasia / epidemiology. DNA Probes, HPV. Diagnosis, Differential. Female. Humans. Middle Aged. Neoplasms, Glandular and Epithelial / diagnosis. Neoplasms, Glandular and Epithelial / epidemiology. Neoplasms, Glandular and Epithelial / virology. Neoplasms, Squamous Cell / epidemiology. Neoplasms, Squamous Cell / virology. Precancerous Conditions / diagnosis. Precancerous Conditions / epidemiology. Precancerous Conditions / virology. Predictive Value of Tests. Uterine Cervical Dysplasia / diagnosis. Uterine Cervical Dysplasia / epidemiology. Uterine Cervical Dysplasia / virology

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  • (PMID = 16803485.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Probes, HPV
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91. Olivas Mendoza G, Mesina Sandoval J, Mata Orozco VM, Hernández M: [Complicated pregnancy with lithiasis and resectable gallbladder cancer. A case report and literature review]. Ginecol Obstet Mex; 2005 Dec;73(12):661-5
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  • Pregnancy complicated with gallbladder disease stone has an incidence of 2-14%, and more than 30% of patients do not respond to medical treatment; therefore, in order to reduce the morbidity and mortality in fetus and mother, surgical management would be required.
  • The current use of ultrasound of high resolution has facilitated the diagnosis and also, in the present clinical case, this imaging modality allowed us to suspect the unusual diagnosis reported, that corresponds to a female of 34 years old with 33 weeks of pregnancy, complicated with symptomatic gallbladder disease stone, whose pain was intractable at the expectant management.
  • The clinical diagnosis was corroborated by ultrasound and the report was: lithiasis, biliary sludge and an intragallbladder image of bilobular polypoid.
  • The patient was submitted to cholecystectomy by laparotomy, whose histopathologic findings were: cholelithiasis and in situ gallbladder adenocarcinoma with an exophytic growing variety.
  • [MeSH-major] Adenocarcinoma. Adenomatous Polyps. Carcinoma in Situ. Cholelithiasis. Gallbladder Neoplasms. Pregnancy Complications. Pregnancy Complications, Neoplastic


92. Achcar Rde O, Nikiforova MN, Dacic S, Nicholson AG, Yousem SA: Mammalian mastermind like 2 11q21 gene rearrangement in bronchopulmonary mucoepidermoid carcinoma. Hum Pathol; 2009 Jun;40(6):854-60
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  • The translocation t(11;19)(q21;p13) results in the gene fusion of mucoepidermoid carcinoma translocated 1-mammalian mastermind like 2 genes that is the major chromosomal abnormality observed in mucoepidermoid carcinomas of salivary glands but has not been studied in bronchopulmonary mucoepidermoid carcinoma.
  • To investigate the importance of the mammalian mastermind like 2 gene rearrangement and mucoepidermoid carcinoma translocated 1-mammalian mastermind like 2 fusion gene in bronchopulmonary mucoepidermoid carcinoma tumorigenesis and its differential diagnosis with primary pulmonary non-small-cell carcinomas, we evaluated the presence of the mammalian mastermind like 2 gene rearrangement and the mucoepidermoid carcinoma translocated 1-mammalian mastermind like 2 fusion in formalin-fixed, paraffin-embedded tissue sections from 17 adult bronchopulmonary mucoepidermoid carcinoma, 16 adenosquamous carcinomas, 24 squamous cell carcinomas, and 41 primary adenocarcinomas by fluorescence in situ hybridization and reverse transcriptase polymerase chain reaction.
  • We detected mammalian mastermind like 2 gene rearrangement by fluorescence in situ hybridization analysis in 13 (77%) of 17 bronchopulmonary mucoepidermoid carcinoma cases (10 of 10 being low grade and 3 of 7 being high grade).
  • Reverse transcriptase polymerase chain reaction analysis confirmed positive fluorescence in situ hybridization results in 6 (43%) of 14 mucoepidermoid carcinoma cases.
  • None of the squamous, adenosquamous, or adenocarcinoma cases revealed the mammalian mastermind like 2 gene rearrangement by fluorescence in situ hybridization, and the mucoepidermoid carcinoma translocated 1-mammalian mastermind like 2 fusion product by reverse transcriptase polymerase chain reaction was not identified specifically in our adenosquamous carcinoma cases.
  • In conclusion, our study demonstrates that mammalian mastermind like 2 gene rearrangement and mucoepidermoid carcinoma translocated 1-mammalian mastermind like 2 fusion product can be detected by fluorescence in situ hybridization and reverse transcriptase polymerase chain reaction analysis performed on low- and high-grade primary bronchopulmonary mucoepidermoid carcinoma and can be used to help discriminate low- and high-grade mucoepidermoid carcinoma from adenocarcinoma, adenosquamous carcinoma, and squamous cell carcinoma mimics in histologically challenging cases.
  • [MeSH-minor] Adenosarcoma / genetics. Adenosarcoma / pathology. Adult. Aged. Aged, 80 and over. Carcinoma, Adenosquamous / genetics. Carcinoma, Adenosquamous / pathology. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / pathology. Female. Gene Fusion. Gene Rearrangement. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Reverse Transcriptase Polymerase Chain Reaction. Translocation, Genetic

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  • (PMID = 19269006.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CRTC1 protein, human; 0 / DNA-Binding Proteins; 0 / MAML2 protein, human; 0 / MECT1-MAML2 fusion protein, human; 0 / Nuclear Proteins; 0 / Oncogene Proteins, Fusion; 0 / Transcription Factors
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93. Schiffman SC, Li Y, Dryden G, Li X, Martin RC: Positive correlation of image analysis by mini-endoscopy with micro-PET scan and histology in rats after esophagoduodenal anastomosis. Surg Endosc; 2010 Nov;24(11):2835-41
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  • In previous studies we have used micro-PET scan to analyze the esophageal adenocarcinoma (EAC) transformation in an intact rat model of esophagoduodenal anastomosis (EDA), in which intestinal metaplasia and EAC were reproduced successfully.
  • CONCLUSIONS: The new mini-endoscope constitutes a practical and reliable tool for diagnosis and regular follow-up of the esophagus in rats.
  • [MeSH-minor] Anastomosis, Surgical. Animals. Apoptosis. Cell Proliferation. Esophagoscopes. Fluorodeoxyglucose F18. In Situ Nick-End Labeling. Miniaturization. Radiopharmaceuticals. Rats. Rats, Sprague-Dawley

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  • [Cites] Dis Esophagus. 2007;20(5):372-8 [17760649.001]
  • [Cites] Gastroenterology. 1970 Feb;58(2):163-74 [5413015.001]
  • [Cites] Clin Cancer Res. 2007 Sep 1;13(17):5176-82 [17785574.001]
  • [Cites] Dig Dis Sci. 2006 Mar;51(3):527-32 [16614962.001]
  • [Cites] Carcinogenesis. 1999 Sep;20(9):1801-8 [10469627.001]
  • [Cites] Appl Spectrosc. 2007 Jun;61(6):579-84 [17650367.001]
  • [Cites] J Surg Res. 2000 Feb;88(2):120-4 [10644476.001]
  • [Cites] N Engl J Med. 1999 Nov 4;341(19):1439 [10547407.001]
  • [Cites] Carcinogenesis. 2000 Feb;21(2):257-63 [10657966.001]
  • [Cites] Dis Esophagus. 2009;22(4):323-30 [19473210.001]
  • [Cites] J Surg Res. 2006 Oct;135(2):337-44 [16926029.001]
  • [Cites] J Surg Res. 2005 Nov;129(1):107-13 [15921698.001]
  • [Cites] Curr Opin Gastroenterol. 1999 Jul;15(4):352-8 [17023971.001]
  • [Cites] Cancer Invest. 2008 Apr-May;26(3):278-85 [18317969.001]
  • [Cites] Ann Surg Oncol. 2007 Jul;14(7):2045-55 [17473952.001]
  • (PMID = 20440518.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA127801-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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94. Lane Z, Hansel DE, Epstein JI: Immunohistochemical expression of prostatic antigens in adenocarcinoma and villous adenoma of the urinary bladder. Am J Surg Pathol; 2008 Sep;32(9):1322-6
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  • [Title] Immunohistochemical expression of prostatic antigens in adenocarcinoma and villous adenoma of the urinary bladder.
  • Adenocarcinomas of the bladder are rare, with the diagnosis dependent on exclusion of secondary involvement by direct extension or metastatic spread from other sites.
  • The recent description of an unusual form of urothelial-type mucinous prostatic adenocarcinoma raises a novel differential diagnosis between adenocarcinomas of the prostate and bladder, and investigation into the utility of classic prostatic immunohistochemical antigens in bladder adenocarcinoma is warranted.
  • We identified 37 primary infiltrating adenocarcinomas of the bladder, which included signet ring cell carcinomas (n=11), urachal adenocarcinomas (n=5), and enteric adenocarcinoma (n=21).
  • Also included for comparison were 3 cases, each of bladder villous adenomas and bladder adenocarcinoma in situ.
  • Of the 37 adenocarcinomas, all were negative for PSA and PSAP (0/37; 0%).
  • In contrast, a minority of bladder adenocarcinomas was labeled with the prostate antigens P501S and PSMA.
  • P501S showed moderate diffuse cytoplasmic staining in 4/37 cases (11%), including 3 enteric-type adenocarcinomas and 1 mucinous adenocarcinoma.
  • Additionally, 1 case of adenocarcinoma in situ demonstrated diffuse cytoplasmic staining for P501S.
  • The granular perinuclear staining pattern of P501S typically seen in prostatic adenocarcinoma was absent in all cases of bladder adenocarcinoma.
  • PSMA showed diffuse cytoplasmic staining in 4/37 (11%) infiltrating adenocarcinomas (including 1 signet ring carcinoma and 3 enteric-type adenocarcinomas), and in 1 case of adenocarcinoma in situ.
  • Membranous PSMA staining was evident in an additional 3 tumors, 1 urachal mucinous adenocarcinoma, 1 nonurachal mucinous and signet ring cell adenocarcinoma, and 1 nonurachal villous adenoma.
  • In conclusion, although all cases of bladder adenocarcinoma examined were negative for PSA and PSAP, the surprising finding that a subset of invasive and in situ adenocarcinomas of the bladder demonstrated immunoreactivity for P501S and PSMA should warrant caution when using these markers in differentiating prostatic from bladder adenocarcinomas.
  • The lack of granular perinuclear staining for P501S and the absence of membranous PSMA staining both favor a bladder adenocarcinoma, although rare cases of villous adenoma and adenocarcinoma did show PSMA membranous staining indistinguishable from that seen in prostate cancer.
  • Although the novel antigens P501S and PSMA are fairly specific and more sensitive in the differential diagnosis of prostate and urothelial carcinoma, care must be taken when adenocarcinomas of the bladder are considered within this differential diagnosis.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma, Villous / metabolism. Antigens, Neoplasm / biosynthesis. Urinary Bladder Neoplasms / metabolism
  • [MeSH-minor] Acid Phosphatase. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Membrane Proteins / biosynthesis. Prostate-Specific Antigen / biosynthesis. Prostatic Neoplasms / metabolism. Prostatic Neoplasms / pathology. Protein Tyrosine Phosphatases / biosynthesis. Tissue Array Analysis

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  • (PMID = 18670358.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Membrane Proteins; 0 / prostein; EC 3.1.3.2 / Acid Phosphatase; EC 3.1.3.2 / prostatic acid phosphatase; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.4.21.77 / Prostate-Specific Antigen
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95. Anandasabapathy S: Novel Endoscopic Techniques for the Detection of Barrett's Dysplasia. Gastrointest Cancer Res; 2008 Mar;2(2):81-4
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  • Barrett's esophagus is highly prevalent in the US population and is the only known precursor of esophageal adenocarcinoma, one of the most lethal and increasingly common cancers in the developed world.
  • Over the past 4 decades, the incidence of esophageal adenocarcinoma has increased some 300% to 500%.
  • This dramatic trend has sparked tremendous interest in the early diagnosis of Barrett's dysplasia.
  • The diagnosis of dysplasia and early cancer in Barrett's esophagus presents a number of challenges.
  • Emerging technologies in the field of endoscopic microscopy and spectroscopy offer the potential for visual biopsies-real-time, in-situ diagnoses that can be rendered without removing tissue.
  • Used as an adjunct to standard white-light endoscopy, these technologies may enhance the detection of dysplasia and early cancer, thus offering the potential for early diagnosis and improved survival.

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  • [Cites] Clin Gastroenterol Hepatol. 2006 Aug;4(8):979-87 [16843068.001]
  • [Cites] Am J Gastroenterol. 1997 Feb;92(2):212-5 [9040193.001]
  • [Cites] Gastroenterology. 1996 Jul;111(1):93-101 [8698231.001]
  • [Cites] Gastroenterology. 2000 Sep;119(3):677-82 [10982761.001]
  • [Cites] Lasers Surg Med. 2003;32(1):10-6 [12516065.001]
  • [Cites] Gastroenterology. 2001 Jun;120(7):1620-9 [11375944.001]
  • [Cites] Endoscopy. 2000 Oct;32(10):756-65 [11068834.001]
  • [Cites] Semin Oncol. 2004 Aug;31(4):450-64 [15297938.001]
  • (PMID = 19259299.001).
  • [ISSN] 1934-7820
  • [Journal-full-title] Gastrointestinal cancer research : GCR
  • [ISO-abbreviation] Gastrointest Cancer Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2630821
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96. Gurney EP, Blank SV: Fortuitous detection of endocervical adenocarcinoma in situ: a report of 2 cases. J Reprod Med; 2009 Jul;54(7):451-3
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  • [Title] Fortuitous detection of endocervical adenocarcinoma in situ: a report of 2 cases.
  • Biopsies revealed adenocarcinoma in situ, and cold-knife conization was performed.
  • [MeSH-major] Adenocarcinoma / pathology. Cervical Intraepithelial Neoplasia / pathology. Endometrial Neoplasms / pathology. Papanicolaou Test. Papillomavirus Infections / pathology. Precancerous Conditions / pathology. Uterine Cervical Neoplasms / pathology. Vaginal Smears / methods


97. Gurbuz A, Karateke A, Kabaca C, Kir G: Atypical glandular cells: improvement in cytohistologic correlation by the 2001 Bethesda system. Int J Gynecol Cancer; 2005 Sep-Oct;15(5):903-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cytology files of 18,955 patients were reviewed for diagnosis of atypical glandular cells of undetermined significance (AGUS), and histopathology files were searched.
  • In reevaluation according to TBS 2001, 31 specimens were reevaluated as atypical glandular cells (AGC) and 3 were reevaluated as adenocarcinoma in situ, 8 as AGC with concomitant squamous cell abnormalities, 1 as atypical squamous cells that cannot exclude high-grade squamous intraepithelial lesions, and 33 as negative.
  • [MeSH-major] Cervix Uteri / pathology. Papanicolaou Test. Uterine Cervical Diseases / diagnosis. Uterine Cervical Diseases / pathology. Vaginal Smears / methods


98. Onuma K, Dabbs DJ, Bhargava R: Mammaglobin expression in the female genital tract: immunohistochemical analysis in benign and neoplastic endocervix and endometrium. Int J Gynecol Pathol; 2008 Jul;27(3):418-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To investigate the potential use of MGB in gynecologic pathology practice, we tested MGB expression by immunohistochemistry on 47 endocervical adenocarcinomas (whole tissue sections of 13 invasive and 35 in situ) and 55 endometrial carcinomas (39 endometrioid and 16 nonendometrioid represented on a single tissue microarray).
  • MGB expression was detected in thirty (77%) of 39 of endometrioid endometrial adenocarcinomas compared with 4 (31%) of 13 endocervical adenocarcinomas.
  • Endocervical adenocarcinoma in situ (AIS) showed either weak (predominantly) or moderate (occasionally) expression in about 40% of the cases in comparison with strong positivity in benign endocervical glandular epithelium.
  • Reduction of MGB staining was seen in transition from benign epithelium to AIS.
  • Frequent MGB expression in endometrioid endometrial adenocarcinoma is significantly different from nonendometrioid carcinoma.
  • Most endocervical adenocarcinomas are negative for MGB, in contrast to mostly positive endometrioid endometrial adenocarcinomas, however, MGB expression alone is not specific enough to distinguish these 2 tumor types.
  • [MeSH-major] Adenocarcinoma / metabolism. Biomarkers, Tumor / biosynthesis. Carcinoma in Situ / metabolism. Neoplasm Proteins / biosynthesis. Uterine Neoplasms / metabolism. Uteroglobin / biosynthesis. Uterus / metabolism

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  • (PMID = 18580321.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Mammaglobin A; 0 / Neoplasm Proteins; 0 / SCGB2A2 protein, human; 9060-09-7 / Uteroglobin
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99. Dacic S: EGFR assays in lung cancer. Adv Anat Pathol; 2008 Jul;15(4):241-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This observation revolutionized understanding of EGFR in lung carcinogenesis and resulted in numerous retrospective studies that correlated patient's response and molecular profile of the lung adenocarcinoma.
  • Multiple methodologic approaches were used including mutational analysis, fluorescence in situ hybridization, and immunohistochemistry.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / drug therapy. Adenocarcinoma / genetics. Carcinoma, Non-Small-Cell Lung / diagnosis. Carcinoma, Non-Small-Cell Lung / drug therapy. Carcinoma, Non-Small-Cell Lung / genetics. Humans. In Situ Hybridization, Fluorescence. Polymerase Chain Reaction. Prognosis


100. Haidopoulos DA, Stefanidis K, Rodolakis A, Pilalis A, Symiakaki I, Diakomanolis E: Histologic implications of Pap smears classified as atypical glandular cells. J Reprod Med; 2005 Jul;50(7):539-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of these, 64 were classified as AGC not otherwise specified (NOS) (56.6%), 48 AGC favor neoplasia (42.5%) and 1 (0.9%) adenocarcinoma in situ.
  • Significant abnormality was found in 30 women (26.5%).
  • Eleven percent of women with smears reported as AGC NOS and 45.8% of those with AGC favor neoplasia had significant abnormality.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Adult. Age Factors. Aged. Aged, 80 and over. Diagnosis, Differential. Endometrial Neoplasms / diagnosis. Endometrial Neoplasms / pathology. Female. Humans. Middle Aged. Retrospective Studies. Uterine Cervical Neoplasms / diagnosis. Uterine Cervical Neoplasms / pathology






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