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1. Denson JL, Keen CE, Froeschle PO, Toy EW, Borman AM: Adiaspiromycosis mimicking widespread malignancy in a patient with pulmonary adenocarcinoma. J Clin Pathol; 2009 Sep;62(9):837-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adiaspiromycosis mimicking widespread malignancy in a patient with pulmonary adenocarcinoma.
  • Adiaspiromycosis, a mycotic disease of small animals, has rarely been reported in humans.
  • Diagnosis is principally made through histological examination.
  • This report describes a case of a patient with low-grade, localised pulmonary adenocarcinoma with occult adiaspiromycosis that radiologically mimicked widespread malignancy.
  • [MeSH-major] Adenocarcinoma, Papillary / pathology. Chrysosporium. Lung Diseases, Fungal / diagnosis. Lung Neoplasms / pathology. Mycoses / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 19734484.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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2. Gärtner H, Maier KP: [Increased carcinoembryonic antigen: what is the diagnosis?]. Dtsch Med Wochenschr; 2005 Oct 28;Suppl 1:95
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  • [Title] [Increased carcinoembryonic antigen: what is the diagnosis?].
  • [MeSH-major] Carcinoembryonic Antigen / blood. Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / blood. Adenocarcinoma / diagnosis. Biomarkers / blood. Humans. Reference Values. Thyroid Neoplasms / blood. Thyroid Neoplasms / diagnosis

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  • (PMID = 16379259.001).
  • [ISSN] 0012-0472
  • [Journal-full-title] Deutsche medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Dtsch. Med. Wochenschr.
  • [Language] ger
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Carcinoembryonic Antigen
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3. Hao Y, Triadafilopoulos G, Sahbaie P, Young HS, Omary MB, Lowe AW: Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma. Gastroenterology; 2006 Sep;131(3):925-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma.
  • BACKGROUND & AIMS: Barrett's esophagus is a precursor of esophageal adenocarcinoma.
  • DNA microarrays that enable a genome-wide assessment of gene expression enhance the identification of specific genes as well as gene expression patterns that are expressed by Barrett's esophagus and adenocarcinoma compared with normal tissues.
  • Barrett's esophagus length has also been identified as a risk factor for progression to adenocarcinoma, but whether there are intrinsic biological differences between short-segment and long-segment Barrett's esophagus can be explored with microarrays.
  • METHODS: Gene expression profiles for endoscopically obtained biopsy specimens of Barrett's esophagus or esophageal adenocarcinoma and associated normal esophagus and duodenum were identified for 17 patients using DNA microarrays.
  • Barrett's esophagus and esophageal adenocarcinoma express a unique set of stromal genes that is distinct from normal tissues but similar to other cancers.
  • Adenocarcinoma also showed lower and higher expression for many genes compared with Barrett's esophagus.
  • Stromal gene expression in Barrett's esophagus and adenocarcinoma is similar, indicating that these changes precede malignant transformation.

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  • (PMID = 16952561.001).
  • [ISSN] 0016-5085
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / P30 DK056339; United States / NIDDK NIH HHS / DK / R01 DK063624; United States / NIDDK NIH HHS / DK / P30 DK56339; United States / NIDDK NIH HHS / DK / R01 DK 063624
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Adhesion Molecules; 0 / Chondroitin Sulfate Proteoglycans; 0 / Cspg2 protein, mouse; 0 / DNA, Neoplasm; 0 / Lectins, C-Type; 0 / POSTN protein, human; 0 / VCAN protein, human; 126968-45-4 / Versicans; 9007-34-5 / Collagen
  • [Other-IDs] NLM/ NIHMS12359; NLM/ PMC2575112
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4. Duncan E, Beckert L: Medical image. Lung metastases in adenocarcinoma. N Z Med J; 2008 Dec 12;121(1287):85
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  • [Title] Medical image. Lung metastases in adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Lung Neoplasms / secondary
  • [MeSH-minor] Aged. Bronchoscopy. Diagnosis, Differential. Humans. Lymphatic Metastasis. Male. Radiography, Thoracic. Tomography, X-Ray Computed

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  • (PMID = 19098974.001).
  • [ISSN] 1175-8716
  • [Journal-full-title] The New Zealand medical journal
  • [ISO-abbreviation] N. Z. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
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5. Cannon R, Shah M, Suydam E, Gucwa A, Bowden T, Holsten SB Jr: Early thrombosis of the superior vena cava in a patient with a central venous catheter and carcinoma of the ampulla of Vater. Am Surg; 2008 Dec;74(12):1195-7
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  • The diagnosis is suggested by the clinical manifestations of facial and upper extremity swelling, dyspnea, and cough.
  • In this report, we present a patient who developed superior vena cava thrombosis after undergoing a short period of central venous catheterization and a Whipple procedure for adenocarcinoma of the ampulla of Vater.
  • [MeSH-major] Adenocarcinoma / complications. Ampulla of Vater / pathology. Catheterization, Central Venous / adverse effects. Common Bile Duct Neoplasms / complications. Superior Vena Cava Syndrome / etiology. Vena Cava, Superior / pathology. Venous Thrombosis / etiology

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  • (PMID = 19097536.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Stephenson SM, Mech KF, Sardi A: Lung cancer screening with low-dose spiral computed tomography. Am Surg; 2005 Dec;71(12):1015-7
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  • Stage IA disease was found in three patients and stage IIIA disease was found in one patient.
  • Adenocarcinoma was present in two patients, adeno-squamous carcinoma in one patient, and squamous cell carcinoma in one patient.
  • However, the disease prevalence was almost double the highest prevalence found in other studies.
  • Clearly, screening chest CT in the community setting is equally efficacious in the diagnosis of lung cancer at earlier stages.

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  • (PMID = 16447470.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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7. Goker BO, Bese T, Ilvan S, Yilmaz E, Demirkiran F: A case with multiple gynecological malignancies. Int J Gynecol Cancer; 2005 Mar-Apr;15(2):372-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fourteen months after the diagnosis of the lymphoma, an endometrial adenocarcinoma was detected as a secondary malignant tumor.
  • Approximately 7 years after the diagnosis of endometrial cancer, vaginal invasive squamous cell carcinoma was diagnosed as the third primary malignancy, and a second-line palliative radiotherapy was applied.
  • The patient died because of the disease.
  • [MeSH-major] Adenocarcinoma / pathology. Endometrial Neoplasms / pathology. Lymphoma, Non-Hodgkin / drug therapy. Neoplasms, Multiple Primary / pathology. Sarcoma / pathology. Uterine Cervical Neoplasms / drug therapy. Vaginal Neoplasms / pathology


8. Houghton O, Jamison J, Wilson R, Carson J, McCluggage WG: p16 Immunoreactivity in unusual types of cervical adenocarcinoma does not reflect human papillomavirus infection. Histopathology; 2010 Sep;57(3):342-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p16 Immunoreactivity in unusual types of cervical adenocarcinoma does not reflect human papillomavirus infection.
  • AIMS: The association between human papillomavirus (HPV) and cervical carcinoma is well known, with HPV being identifiable in almost all cervical squamous carcinomas and most adenocarcinomas.
  • However, the prevalence of HPV in unusual morphological types of cervical adenocarcinoma has not been investigated extensively.
  • The aim was to determine HPV status in a series of primary cervical adenocarcinomas, enriched for unusual morphological types.
  • METHODS AND RESULTS: Sixty-three cervical adenocarcinomas, comprising those of usual type (n = 43), minimal deviation type (n = 4), gastric type (n = 3), intestinal type (n = 3), mesonephric type (n = 3), clear cell type (n = 4), serous type (n = 2) and hepatoid type (n = 1) underwent linear array HPV genotyping and immunohistochemistry for p16.
  • Seventy-eight per cent of usual-type adenocarcinomas were HPV-positive, as was the single serous carcinoma in which there was sufficient DNA for analysis.
  • In contrast, all minimal deviation adenocarcinomas and those of gastric, intestinal, mesonephric and clear cell types were HPV-negative, as was the single hepatoid carcinoma.
  • All usual-type adenocarcinomas exhibited p16 immunoreactivity (diffuse staining in all but one case), as did 11 of 20 of those of unusual morphological type (five focal, six diffuse).
  • CONCLUSIONS: Most, but not all, cervical adenocarcinomas of usual type contain HPV, but those of unusual morphological type are almost always HPV-negative.
  • This has implications for the efficacy of HPV vaccination in the prevention of cervical adenocarcinoma.
  • A significant proportion of cervical adenocarcinomas are p16-positive in the absence of HPV, illustrating that in these neoplasms diffuse p16 immunoreactivity is not a reliable surrogate marker of the presence of high-risk HPV.
  • [MeSH-major] Adenocarcinoma / virology. Biomarkers, Tumor / metabolism. Neoplasm Proteins / metabolism. Papillomavirus Infections / complications. Uterine Cervical Neoplasms / virology

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  • [Copyright] © 2010 Blackwell Publishing Limited.
  • (PMID = 20727021.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Viral; 0 / Neoplasm Proteins; 0 / P16 protein, human
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9. Fong D, Steurer M, Obrist P, Barbieri V, Margreiter R, Amberger A, Laimer K, Gastl G, Tzankov A, Spizzo G: Ep-CAM expression in pancreatic and ampullary carcinomas: frequency and prognostic relevance. J Clin Pathol; 2008 Jan;61(1):31-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIMS: Pancreatic adenocarcinoma is an aggressive gastrointestinal malignancy with only a few long-term survivors even after radical surgery.
  • [MeSH-major] Ampulla of Vater. Antigens, Neoplasm / metabolism. Biomarkers, Tumor / metabolism. Cell Adhesion Molecules / metabolism. Common Bile Duct Neoplasms / metabolism. Pancreatic Neoplasms / metabolism
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Proteins / metabolism. Neoplasm Staging. Prognosis. Retrospective Studies. Survival Analysis

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  • (PMID = 16775119.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Cell Adhesion Molecules; 0 / EPCAM protein, human; 0 / Neoplasm Proteins
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10. Dainty LA, Krivak TC, Webb JC, Zahn CM, Elkas JC, Chernofsky MR, Rose GS, Maxwell GL: Diffuse laminar endocervical glandular hyperplasia: a case report. Int J Gynecol Cancer; 2009 Aug;19(6):1091-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Colposcopic-directed cervical biopsies were diagnosed as adenocarcinoma, suggestive of minimal deviation adenocarcinoma.
  • CONCLUSIONS: Diffuse laminar endocervical glandular hyperplasia is an uncommon histological type of pseudoneoplastic glandular lesions that may be found in the cervix, and this entity should be considered in the differential diagnosis of a potentially malignant endocervical glandular lesion.
  • [MeSH-major] Cervix Uteri / pathology. Neoplasms, Glandular and Epithelial / diagnosis. Uterine Cervical Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Diagnosis, Differential. Female. Humans. Hyperplasia / diagnosis. Hyperplasia / pathology. Postpartum Period. Precancerous Conditions / diagnosis. Young Adult


11. Stipa F, Alessandroni L, Cimitan A, Burza A, Cavallotti C, Cavallini M, Tersigni R, Ziparo V: [Pancreaticoduodenectomy for adenocarcinoma of the pancreatic head and papilla of Vater]. Minerva Chir; 2009 Aug;64(4):395-406
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pancreaticoduodenectomy for adenocarcinoma of the pancreatic head and papilla of Vater].
  • [Transliterated title] Duodenocefalopancreatectomia per adenocarcinoma della testa del pancreas e della papilla di Vater.
  • AIM: The authors report their consecutive experience in the surgical management of adenocarcinoma (ADC) of head of pancreas and papilla of Vater, in order to review the available literature.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy

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  • (PMID = 19648859.001).
  • [ISSN] 0026-4733
  • [Journal-full-title] Minerva chirurgica
  • [ISO-abbreviation] Minerva Chir
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 79
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12. Apgar BS, Kaufman AH, George-Nwogu U, Kittendorf A: Treatment of menorrhagia. Am Fam Physician; 2007 Jun 15;75(12):1813-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Endometrial biopsy is effective for diagnosing precancerous lesions and adenocarcinoma but not for intracavitary lesions.
  • [MeSH-minor] Adult. Biopsy. Catheter Ablation. Endometrium / pathology. Female. Humans. Hysteroscopy. Laser Therapy. Leiomyoma / diagnosis. Leiomyoma / surgery. Menstruation / physiology. Progestins / administration & dosage. Uterine Neoplasms / diagnosis. Uterine Neoplasms / surgery

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  • [SummaryForPatientsIn] Am Fam Physician. 2007 Jun 15;75(12):1820 [17619524.001]
  • (PMID = 17619523.001).
  • [ISSN] 0002-838X
  • [Journal-full-title] American family physician
  • [ISO-abbreviation] Am Fam Physician
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Progestins
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13. Yeh TS, Liu KH, Su MY, Lin CH, Chiu CT, Tseng JH: Laparoscopically assisted bowel surgery in an era of double-balloon enteroscopy: from inside to outside. Surg Endosc; 2009 Apr;23(4):739-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Laparoscopically assisted bowel resection was performed for 27 patients, converted laparotomy for 6 patients, and laparoscopic diagnosis alone for 1 patient.
  • The pathologic diagnoses included gastrointestinal stromal tumor (GIST) for eight patients, primary adenocarcinoma for three patients, lymphoma for three patients, Meckel's diverticulum for three patients, angiodysplasia for three patients, ulcer for two patients, lipoma for four patients, metastasis for three patients, jejunal diverticulosis for two patients, and tuberculosis ileitis, ileal varix, and lymphangioma for one patient each.
  • After a follow-up period of 14+/-3 months, 29 patients were well without disease recurrence.

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  • (PMID = 18622544.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
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14. Wakatsuki T, Irisawa A, Takagi T, Koyama Y, Hoshi S, Takenoshita S, Abe M, Ohira H: Primary adenocarcinoma of the minor duodenal papilla. Yonsei Med J; 2008 Apr 30;49(2):333-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary adenocarcinoma of the minor duodenal papilla.
  • A biopsy specimen showed moderately differentiated adenocarcinoma.
  • For treatment, pylorus-preserving pancreatoduodenectomy was performed, and histological findings revealed a well-differentiated adenocarcinoma that originated in the minor duodenal papilla.
  • Primary adenocarcinoma of the minor duodenal papilla is extremely rare.
  • Our case is the first report of primary adenocarcinoma of the minor duodenal papilla at an early stage with no infiltration into muscularis propria of the duodenum and pancreas.
  • [MeSH-major] Adenocarcinoma / pathology. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 18452274.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2615313
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16. Li WX, Zheng QQ, Wang P, Li YQ, Chen GH: [Fourier transform infrared spectroscopy study on normal and malignant tissues of cervix]. Guang Pu Xue Yu Guang Pu Fen Xi; 2006 Oct;26(10):1833-7
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  • [Title] [Fourier transform infrared spectroscopy study on normal and malignant tissues of cervix].
  • Fourier transform infrared spectroscopy (FTIR) was used to investigate 35 cervical tissues , including 17 squamous cell carcinoma of cervical samples, and 5 adenocarcinoma of cervical samples, 13 normal cervical samples.
  • The utilization of FTIR spectra in cervical tissues is expected to be a hopeful method in cervical cancer screening and clinical diagnosis in the future.
  • [MeSH-minor] Adult. Aged. Female. Humans. Middle Aged. Pregnancy. Spectroscopy, Fourier Transform Infrared / methods. Uterine Cervical Neoplasms / diagnosis. Uterine Cervical Neoplasms / pathology


17. Smeulders N, Sudhakaran N, Wilcox DT, Ransley PG: Adenocarcinoma at the ureterosigmoidostomy site in a 16-year-old demonstrates the importance of screening in children. J Pediatr Urol; 2008 Jun;4(3):234-5
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  • [Title] Adenocarcinoma at the ureterosigmoidostomy site in a 16-year-old demonstrates the importance of screening in children.
  • We report the death of a 17-year-old male exstrophy patient from adenocarcinoma arising at the ureterosigmoidostomy.
  • [MeSH-major] Adenocarcinoma / etiology. Bladder Exstrophy / surgery. Colon, Sigmoid / surgery. Colonic Neoplasms / etiology. Ureterostomy / adverse effects
  • [MeSH-minor] Adolescent. Anastomosis, Surgical / adverse effects. Colectomy / methods. Cystectomy / adverse effects. Cystectomy / methods. Diagnosis, Differential. Fatal Outcome. Humans. Male. Postoperative Complications. Tomography, X-Ray Computed

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  • (PMID = 18631934.001).
  • [ISSN] 1873-4898
  • [Journal-full-title] Journal of pediatric urology
  • [ISO-abbreviation] J Pediatr Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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18. Mocanu L, Cîmpean AM, Raica M: Value of antimesothelioma HBME-1 in the diagnosis of inflammatory and malignant pleural effusions. Rom J Morphol Embryol; 2006;47(4):351-5
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  • [Title] Value of antimesothelioma HBME-1 in the diagnosis of inflammatory and malignant pleural effusions.
  • Pleural effusions occur in many benign and malignant conditions.
  • The differentiation of mesothelial hyperplasia, malignant epithelial mesothelioma and metastatic adenocarcinoma in cytologic specimens is often difficult.
  • In this study, immunostaining was performed on 30 smears from seven patients with inflammatory pleural effusions, 21 patients with metastatic pleural effusions and two patients with malignant epithelial mesothelioma.
  • One of the malignant mesothelioma was positive for HBME-1 with thick and thin membrane pattern.
  • Metastatic tumor cells were positive for HBME-1 in seven (33.33%) cases; the staining pattern in metastatic adenocarcinoma cells was thin membrane and focal cytoplasmic.
  • HBME-1 has a moderate sensibility and specificity for mesothelial cells and can be used as part of a panel for differentiation of malignant and reactive mesothelial cells from adenocarcinoma in pleural effusions.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Mesothelioma / pathology. Pleural Effusion, Malignant / diagnosis

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  • (PMID = 17392981.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / HBME-1 antigen
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19. You J, Xu L, Zheng GY, Qiu JF: [Diagnosis, treatment, and prognosis of primary appendiceal tumors: analysis of 37 cases]. Zhonghua Yi Xue Za Zhi; 2008 Jul 15;88(27):1909-11
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  • [Title] [Diagnosis, treatment, and prognosis of primary appendiceal tumors: analysis of 37 cases].
  • OBJECTIVE: To investigate the pathology, diagnosis,treatment, and prognosis of primary appendiceal tumors.
  • All 37 cases received surgical operation with the diagnosis confirmed by pathology.
  • The pathological types included carcinoid tumor (n=12), mucinous tumor (n=17), and adenocarcinoma (n=8).
  • The 1, 3, and 5-year survival rates of the primary appendix carcinoid tumor, mucinous tumor, and adenocarcinoma were 100.0%, 100.0%, and 91.7%, 100.0%, 86.7%, and 71.5%, and 75.0%, 50.0%, and 50.0% respectively.
  • CONCLUSION: A rare disease, appendiceal tumors lack specific clinical features.
  • Intra-operative exploration and frozen section are very important for diagnosis and operation choice.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Appendiceal Neoplasms / surgery

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  • (PMID = 19040005.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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20. Peters K, Klöppel G: [Undifferentiated pancreatic carcinomas. Leap into chaos]. Pathologe; 2005 Feb;26(1):18-21
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  • Undifferentiated pancreatic carcinomas are rare anaplastic variants of ductal adenocarcinoma of the pancreas.
  • They have to be distinguished immunohistochemically from metastases of malignant melanoma or an infiltrating sarcoma.
  • [MeSH-minor] Adenocarcinoma / pathology. Carcinoma, Pancreatic Ductal / pathology. Diagnosis, Differential. Humans. Immunohistochemistry

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  • [Cites] Int J Cancer. 2001 May 20;95(3):194-7 [11307154.001]
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  • (PMID = 15592673.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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21. Beal HN, Stone J, Beckmann MJ, McAsey ME: Endometrial cells identified in cervical cytology in women > or = 40 years of age: criteria for appropriate endometrial evaluation. Am J Obstet Gynecol; 2007 Jun;196(6):568.e1-5; discussion 568.e5-6
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  • There were 4 cases of complex hyperplasia with atypia, 2 from patients < or = 50 years, 1 was asymptomatic; 4 cases of adenocarcinoma were identified, all from women > 50 years.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adult. Endometrial Hyperplasia / diagnosis. Endometrial Neoplasms / diagnosis. Endometritis / diagnosis. Female. Follow-Up Studies. Humans. Leiomyoma / diagnosis. Polyps / diagnosis. Postmenopause. Premenopause. Uterine Hemorrhage / etiology


22. Kountourakis P, Ardavanis A, Mantzaris I, Mitsaka D, Rigatos G: Urachal mucinous adenocarcinoma: a case report. J BUON; 2007 Oct-Dec;12(4):547-8
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  • [Title] Urachal mucinous adenocarcinoma: a case report.
  • Adenocarcinomas account for 0.5-2% of all bladder cancers.
  • Urachal carcinoma is a rare neoplasm which represents 0.01% of all cancers in adults and account for one third of bladder adenocarcinomas.
  • A 65-year-old white man with an urachal mucinous adenocarcinoma is reported.
  • He underwent a partial cystectomy and en block excision of the umbilical ligament and remains disease-free after one year.
  • The development of this rare neoplasm should not be clearly dissociated from multiple sclerosis, either aetiologically sharing an unidentified common causative factor or due to its treatment with mitoxantrone.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / surgery. Urachus. Urinary Bladder Neoplasms / diagnosis. Urinary Bladder Neoplasms / surgery

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  • (PMID = 18067216.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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23. Kasahara K, Arao T, Sakai K, Matsumoto K, Sakai A, Kimura H, Sone T, Horiike A, Nishio M, Ohira T, Ikeda N, Yamanaka T, Saijo N, Nishio K: Impact of serum hepatocyte growth factor on treatment response to epidermal growth factor receptor tyrosine kinase inhibitors in patients with non-small cell lung adenocarcinoma. Clin Cancer Res; 2010 Sep 15;16(18):4616-24
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  • [Title] Impact of serum hepatocyte growth factor on treatment response to epidermal growth factor receptor tyrosine kinase inhibitors in patients with non-small cell lung adenocarcinoma.
  • EXPERIMENTAL DESIGN: We retrospectively analyzed the serum concentrations of 13 molecules in a cohort of 95 patients with non-small cell lung adenocarcinoma who received EGFR-TKI treatment at three centers.
  • RESULTS: The concentrations of HGF and VEGF were significantly higher among patients with progressive disease than among those without progressive disease (P < 0.0001).
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / diagnosis. Carcinoma, Non-Small-Cell Lung / drug therapy. Hepatocyte Growth Factor / blood. Lung Neoplasms / diagnosis. Lung Neoplasms / drug therapy. Protein Kinase Inhibitors / therapeutic use. Receptor, Epidermal Growth Factor / antagonists & inhibitors
  • [MeSH-minor] Adenocarcinoma / blood. Adenocarcinoma / diagnosis. Adenocarcinoma / drug therapy. Adenocarcinoma / mortality. Adult. Aged. Antineoplastic Agents / therapeutic use. Biomarkers, Pharmacological / blood. Biomarkers, Tumor / blood. Biomarkers, Tumor / physiology. Cohort Studies. Female. Humans. Male. Middle Aged. Prognosis. Retrospective Studies

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  • [Copyright] ©2010 AACR.
  • (PMID = 20679350.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Biomarkers, Pharmacological; 0 / Biomarkers, Tumor; 0 / Protein Kinase Inhibitors; 67256-21-7 / Hepatocyte Growth Factor; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
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24. Baron M, Hamou L, Laberge S, Callonnec F, Tielmans A, Dessogne P: Metastatic spread of gynaecological neoplasms to the adrenal gland: case reports with a review of the literature. Eur J Gynaecol Oncol; 2008;29(5):523-6
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  • The aim of our study was to present four cases of metastases to the adrenal gland due to endometrial adenocarcinoma, ovarian and cervical cancer.
  • CT scan and MRI have been previously used in an attempt to define the nature of the adrenal mass but this approach is of limited value in diagnosis.
  • Image-guided pathological confirmation of an adrenal lesion may significantly change the staging or management of the primary neoplasm.


25. Sharma P: Narrow band imaging in Barrett's esophagus. Clin Gastroenterol Hepatol; 2005 Jul;3(7 Suppl 1):S21-2
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  • Barrett's esophagus is the premalignant lesion for esophageal and esophagogastric junction adenocarcinoma.
  • Currently, the diagnosis of metaplastic and dysplastic mucosa within the esophagus requires endoscopy with biopsy examination of abnormal-appearing tissue.

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  • (PMID = 16012989.001).
  • [ISSN] 1542-3565
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 9
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26. Campisi A, Brancatelli G, Vullierme MP, Levy P, Ruszniewski P, Vilgrain V: Are pancreatic calcifications specific for the diagnosis of chronic pancreatitis? A multidetector-row CT analysis. Clin Radiol; 2009 Sep;64(9):903-11
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  • [Title] Are pancreatic calcifications specific for the diagnosis of chronic pancreatitis? A multidetector-row CT analysis.
  • AIM: To retrospectively establish the most frequently encountered diagnoses in patients with pancreatic calcifications and to investigate whether the association of certain findings could be helpful for diagnosis.
  • RESULTS: Patients had chronic pancreatitis (n=70), neuroendocrine tumours (n=14), intraductal papillary mucinous neoplasm (n=11), pancreatic adenocarcinoma (n=4), serous cystadenoma (n=4).
  • Four CT findings had a specificity of over 60% for the diagnosis of chronic pancreatitis: parenchymal calcifications, intraductal calcifications, parenchymal atrophy, and cystic lesions.
  • When at least three of these four criteria were present, a specificity of 79% for the diagnosis of chronic pancreatitis was achieved.
  • The presence of a combination of CT findings can suggest chronic pancreatitis and be helpful in diagnosis.

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  • [ErratumIn] Clin Radiol. 2009 Nov;64(11):1139. Ruzniewski, P [corrected to Ruszniewski, P]
  • (PMID = 19664481.001).
  • [ISSN] 1365-229X
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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27. Poyet R, Kerebel S, Pons F, Cellarier GR, Bouchiat C, Jego C, Laurent P, Carlioz R: [Recurrent infective endocarditis. A case report]. Ann Cardiol Angeiol (Paris); 2010 Feb;59(1):44-7
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  • This recurrence leads to the diagnosis of caecal adenocarcinoma by coloscopy, preceded and guided by PET scanner.
  • [MeSH-major] Adenocarcinoma / diagnosis. Cecal Neoplasms / diagnosis. Endocarditis, Bacterial / diagnosis. Enterococcus faecalis. Gram-Positive Bacterial Infections / diagnosis. Opportunistic Infections / diagnosis. Streptococcal Infections / diagnosis. Streptococcus bovis. Streptococcus oralis


28. Mahovlić V, Ovanin-Rakić A, Skopljanac-Macina L, Barisić A, Rajhvajn S, Juric D, Projić IS, Ilić-Forko J, Babić D, Skrablin-Kucić S, Bozikov J: Digital morphometry of cytologic aspirate endometrial samples. Coll Antropol; 2010 Mar;34(1):45-51
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  • Unlike cervical cytology, morphological cytology criteria in the differential diagnosis of endometrium have not yet been clearly defined, and methods to allow for more precise evaluation of endometrium status have been searched for.
  • The aim of the present study was to assess the value of morphometric nucleus analysis of cytologic aspirate endometrial samples in proliferative, hyperplastic and malignant endometrium by use of digital image analysis.
  • Morphometric analysis was performed on archival cytologic aspirate endometrial samples (at least 10 per group) stained according to Papanicolaou (n = 77) and May-Grünwald-Giemsa (MGG; n = 80) with the following histopathologic diagnoses: proliferative endometrium, hyperplasia simplex, hyperplasia complex, hyperplasia complex atypica, and adenocarcinoma endometriodes endometrii (grade I, II and III).
  • Multivariate analysis (ANOVA) distinguished malignant, hyperplastic and proliferative endometrium according to all morphometric variables with both staining methods (p < 0.05).
  • However, on interactive testing of the groups (Kruskal-Wallis test), hyperplasias without atypia yielded no significant differences (p > 0.05) from atypical hyperplasia, adenocarcinoma and proliferative endometrium only according to the nucleus form factor and elongation factor (Papanicolaou stain), whereas malignant and atypical hyperplastic endometrium (MGG stain) differed statistically significantly (p < 0.05) from proliferative and hyperplastic endometrium without atypia according to all study parameters except for the nucleus form factor (p > 0.05).
  • According to the cytologic staining method, morphometric parameters were considerably higher in MGG stained endometrial samples, reaching the level of statistical significance (p < 0.05) except for the nucleus form factor and elongation factor (p > 0.05) in the groups of hyperplasia simplex and complex, well differentiated adenocarcinoma (form factor) and atypical hyperplasia (elongation factor).
  • A combination of cytomorphology and the morphometric variables assessed in this study can yield useful information on the cytologic state of endometrium, with special reference to the possible differentiation of the group of hyperplasia without atypia from the group of adenocarcinoma and atypical hyperplasia.
  • [MeSH-minor] Adenocarcinoma / pathology. Biopsy, Needle. Cell Division. Eosine Yellowish-(YS). Female. Humans. Methylene Blue. Papanicolaou Test. Vaginal Smears

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  • (PMID = 20437635.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Croatia
  • [Chemical-registry-number] 0 / May-Grunwald Giemsa; T42P99266K / Methylene Blue; TDQ283MPCW / Eosine Yellowish-(YS)
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29. Raman A, Sternbach J, Babajide A, Sheth K, Schwaitzberg SD: When does testing for GERD become cost effective in an integrated health network? Surg Endosc; 2010 Jun;24(6):1245-9
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  • BACKGROUND: Gastroesophageal reflux (GERD) is the most common gastrointestinal disorder, affecting as many as 14% of the US population.
  • Rising rates of esophageal adenocarcinoma are seen in this population, and chronic proton pump inhibitor (PPI) use does not normalize cancer risk.
  • Bravo + barium swallow + EGD testing to screen patients for possible esophageal adenocarcinoma paid for itself in 42 months.
  • CONCLUSIONS: Significant savings can be realized through early use of upper endoscopy, Bravo testing, barium swallow, and manometry to identify patients that are taking double-dose PPIs unnecessarily based on presumptive diagnosis of GERD.
  • [MeSH-major] Cost of Illness. Delivery of Health Care, Integrated / economics. Endoscopy, Gastrointestinal / economics. Gastroesophageal Reflux / diagnosis. Manometry / economics. Proton Pump Inhibitors / administration & dosage. Quality Assurance, Health Care
  • [MeSH-minor] Cost-Benefit Analysis. Dose-Response Relationship, Drug. Early Diagnosis. Humans. Retrospective Studies. United States

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  • [Cites] Br J Gen Pract. 2001 Sep;51(470):703-11 [11593830.001]
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  • (PMID = 19997935.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Proton Pump Inhibitors
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30. Yamaguchi K, Ogawa Y, Yokohata K, Konomi H, Nakamura M, Nagata S, Tanaka M: [Recent advances in diagnosis of pancreatic cancer]. Gan To Kagaku Ryoho; 2005 May;32(5):612-6
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  • [Title] [Recent advances in diagnosis of pancreatic cancer].
  • Possible discovery of pancreatic carcinoma as a diagnostic clue to diabetes mellitus, and intraductal papillary-mucinous neoplasm are introduced based on our clinical experience.
  • [MeSH-major] Biomarkers, Tumor / blood. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Papillary / diagnosis. Aged. Carcinoma, Pancreatic Ductal / diagnosis. Cholangiopancreatography, Endoscopic Retrograde. Diabetes Mellitus / diagnosis. Female. Humans. Male. Prognosis

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  • (PMID = 15918559.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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31. Yamashita S, Saenko V: Mechanisms of Disease: molecular genetics of childhood thyroid cancers. Nat Clin Pract Endocrinol Metab; 2007 May;3(5):422-9
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  • [Title] Mechanisms of Disease: molecular genetics of childhood thyroid cancers.
  • Papillary adenocarcinoma is the most prevalent malignant tumor of the thyroid in children and adults with radiation-induced or sporadic cancer.
  • Such differences in the distribution of gene abnormalities in radiation-related cancers implies that they associate with patients' age at exposure and diagnosis, clinicopathological manifestations of disease and depend on an individual's genetic characteristics.
  • [MeSH-major] Adenocarcinoma, Papillary / genetics. Adenocarcinoma, Papillary / pathology. Thyroid Neoplasms / genetics. Thyroid Neoplasms / pathology
  • [MeSH-minor] Child. Genetic Predisposition to Disease. Humans. Mutation. Polymorphism, Genetic

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  • (PMID = 17452969.001).
  • [ISSN] 1745-8374
  • [Journal-full-title] Nature clinical practice. Endocrinology & metabolism
  • [ISO-abbreviation] Nat Clin Pract Endocrinol Metab
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 67
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32. Huo Z, Liu HR, Wan JW: [Atypical adenomatous hyperplasia of lung: clinicopathologic study of 8 cases and review of literature]. Zhonghua Bing Li Xue Za Zhi; 2007 May;36(5):292-6
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  • [Title] [Atypical adenomatous hyperplasia of lung: clinicopathologic study of 8 cases and review of literature].
  • OBJECTIVE: To study the clinicopathologic and immunohistochemical features of atypical adenomatous hyperplasia (AAH) of lung.
  • Three patients had past history of non-pulmonary tumors, while 4 patients had lung adenocarcinoma.
  • There was no evidence of local recurrence or disease progression in the 7 patients with post-operative follow-up information available (mean duration of follow up = 23 months).
  • Four cases of AAH were associated with pulmonary adenocarcinoma.
  • The adenocarcinoma cells were diffusely positive for TTF-1 (4/4), variably positive for p16 (2/4), Ki-67 (with proliferation index ranging from 2% to 40%), p53 (1/4) and EGFR (3/4), and negative for c-erbB-2 (0/4).
  • CONCLUSIONS: AAH of lung is associated with pulmonary adenocarcinoma.
  • Diagnosis of AAH requires correlation with CT findings and pathologic examination.
  • [MeSH-major] Adenocarcinoma / pathology. Adenomatosis, Pulmonary / pathology. Lung Neoplasms / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adult. DNA-Binding Proteins / metabolism. Female. Follow-Up Studies. Humans. Hyperplasia / metabolism. Hyperplasia / pathology. Hyperplasia / surgery. Ki-67 Antigen / metabolism. Male. Middle Aged. Neoplasm Proteins / metabolism. Precancerous Conditions / metabolism. Precancerous Conditions / pathology. Precancerous Conditions / surgery

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  • (PMID = 17706134.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Ki-67 Antigen; 0 / Neoplasm Proteins; 0 / P16 protein, human; 0 / TTF1 protein, human
  • [Number-of-references] 18
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33. Buitrago W, Joseph AK: Sebaceous carcinoma: the great masquerader: emgerging concepts in diagnosis and treatment. Dermatol Ther; 2008 Nov-Dec;21(6):459-66
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  • [Title] Sebaceous carcinoma: the great masquerader: emgerging concepts in diagnosis and treatment.
  • It frequently masquerades as inflammatory conditions or as other tumors leading to delay in diagnosis, inappropriate treatment and increased morbidity and mortality.
  • Greater awareness and understanding of SC and its behavior has led to earlier diagnosis and appropriate treatment.
  • [MeSH-major] Adenocarcinoma, Sebaceous / therapy. Eye Neoplasms / therapy. Sebaceous Gland Neoplasms / therapy
  • [MeSH-minor] Humans. Lymphatic Metastasis. Mohs Surgery. Muir-Torre Syndrome / complications. Neoplasm Metastasis. Neoplasm Recurrence, Local. Referral and Consultation. Time Factors

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  • (PMID = 19076624.001).
  • [ISSN] 1529-8019
  • [Journal-full-title] Dermatologic therapy
  • [ISO-abbreviation] Dermatol Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 74
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34. Akbulut S, Ulku A, Senol A, Tas M, Yagmur Y: Left-sided appendicitis: review of 95 published cases and a case report. World J Gastroenterol; 2010 Nov 28;16(44):5598-602
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  • Sixty-six patients had SIT, 23 had MM, three had cecal malrotation, and two had a previously unnoted congenital abnormality.
  • The diagnosis was established preoperatively in 49 patients, intraoperatively in 19, and during the postoperative period in five; 14 patients were aware of having this anomaly.
  • Histopathological examination of the appendix specimens revealed adenocarcinoma in only two of 95 patients.
  • CONCLUSION: The diagnosis of left lower quadrant pain is based on well-established clinical symptoms, physical examination and physician's experience.

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  • (PMID = 21105193.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2992678
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35. Yang SX, Kummar S, Steinberg SM, Murgo AJ, Gutierrez M, Rubinstein L, Nguyen D, Kaur G, Chen AP, Giranda VL, Tomaszewski JE, Doroshow JH, National Cancer Institute Phase 0 Working Group: Immunohistochemical detection of poly(ADP-ribose) polymerase inhibition by ABT-888 in patients with refractory solid tumors and lymphomas. Cancer Biol Ther; 2009 Nov;8(21):2004-9
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  • RESULTS: Baseline PAR levels were moderate to high in three patients with non-Hodgkin lymphomas, and one each with small cell lung cancer, squamous cell carcinoma of the tongue and melanoma; low in two patients with cutaneous T-cell lymphoma and one with adenocarcinoma of external ear canal.
  • [MeSH-minor] Blotting, Western. Cell Line, Tumor. Drug Resistance, Neoplasm. Humans. Immunohistochemistry. Poly(ADP-ribose) Polymerases / biosynthesis

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  • [CommentIn] Cancer Biol Ther. 2009 Nov;8(21):2010-2 [20037466.001]
  • (PMID = 19823047.001).
  • [ISSN] 1555-8576
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CO / N01-CO-12400
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzimidazoles; 0 / Enzyme Inhibitors; 0 / Poly(ADP-ribose) Polymerase Inhibitors; 01O4K0631N / veliparib; EC 2.4.2.30 / PARP1 protein, human; EC 2.4.2.30 / Poly(ADP-ribose) Polymerases
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36. Brown YK, Knowles S, Fiorello CV, Camus MS, Howerth EW: Pathology in practice. Morphologic diagnosis: Uterine adenocarcinoma with metastasis to the lungs, diaphragm, spleen, mesentery, and cecum. J Am Vet Med Assoc; 2010 Dec 1;237(11):1257-9
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  • [Title] Pathology in practice. Morphologic diagnosis: Uterine adenocarcinoma with metastasis to the lungs, diaphragm, spleen, mesentery, and cecum.
  • [MeSH-major] Adenocarcinoma / veterinary. Rabbits. Uterine Neoplasms / veterinary

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  • (PMID = 21118010.001).
  • [ISSN] 0003-1488
  • [Journal-full-title] Journal of the American Veterinary Medical Association
  • [ISO-abbreviation] J. Am. Vet. Med. Assoc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Marquez Moreno AJ, Gomez Rebollo C, Antuña Calle F, Perez Villa L, Sanchez Carrillo JJ, Julve Villalta E, Blanes Berenguel A, Martin Palanca A: Urachal adenocarcinoma with late brain metastases. Arch Esp Urol; 2010 Sep;63(7):550-4
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  • [Title] Urachal adenocarcinoma with late brain metastases.
  • OBJECTIVE: To describe a case of urachal adenocarcinoma with late brain metastases in a sixty one year old man who presented abdominal discomfort and hematuria during six months.
  • The histopathologic diagnosis was mucin-secreting urachal adenocarcinoma.
  • After five years without disease the patient suffered lung and brain metastases.
  • CONCLUSIONS: Urachal adenocarcinoma is a tumor which must be distinguished of primary bladder adeno-carcinoma.
  • The mucing-secreting adenocarcinoma can be associated with calcifications that can be demostrated on imaging studies.
  • Late metastases without signs of local recurrence (after five years without disease) are an infrequent clinical-pathologic finding.
  • [MeSH-major] Adenocarcinoma / secondary. Brain Neoplasms / secondary. Urachus

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  • (PMID = 20945591.001).
  • [ISSN] 1576-8260
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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38. Navarro M, Ruiz I, Martín G, Cruz JJ: Patient with disseminated intravascular coagulation as the first manifestation of adenocarcinoma of the prostate. Risks of prostatic biopsy. Prostate Cancer Prostatic Dis; 2006;9(2):190-1
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  • [Title] Patient with disseminated intravascular coagulation as the first manifestation of adenocarcinoma of the prostate. Risks of prostatic biopsy.
  • Disseminated intravascular coagulation (DIC) can be a rare initial manifestation of adenocarcinoma of the prostate.
  • The performance of a prostate biopsy in this situation exacerbated the initial coagulation disorder.
  • This case highlights the risks of prostate biopsy in patients with a suspicion of advanced adenocarcinoma of the prostate.
  • [MeSH-major] Adenocarcinoma / diagnosis. Biopsy, Needle / adverse effects. Disseminated Intravascular Coagulation / diagnosis. Prostatic Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Fatal Outcome. Humans. Male. Risk Assessment

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  • (PMID = 16331297.001).
  • [ISSN] 1365-7852
  • [Journal-full-title] Prostate cancer and prostatic diseases
  • [ISO-abbreviation] Prostate Cancer Prostatic Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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39. Matsushima H, Oda T, Hasejima N, Kou E, Kadoyama C, Takezawa S: [Pulmonary adenocarcinoma with multiloculated cystic change]. Nihon Kokyuki Gakkai Zasshi; 2007 Jul;45(7):556-9
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  • [Title] [Pulmonary adenocarcinoma with multiloculated cystic change].
  • A 63-year-old man was admitted to our hospital for evaluation of an abnormal chest X-ray film finding.
  • The pathological examination of trans-bronchial lung biopsy specimen revealed adenocarcinoma.
  • The histological examination showed that papillary adenocarcinoma proliferated along the alveolar walls and that the walls of the multiloculated cystic lesions were composed of cancer cells.
  • We speculated that adenocarcinoma cells extended along the alveolar walls and destroyed the alveoli without disrupting the overall lung architecture, resulting in enlarged multiloculated cystic lesions.
  • [MeSH-major] Adenocarcinoma / pathology. Cysts / pathology. Lung Neoplasms / pathology

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  • (PMID = 17682467.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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40. Le Bret T, Tranbaloc P, Benbunan JL, Salet-Lizée D, Villet R: [Endometrial choriocarcinoma in peri-menopausal women]. J Gynecol Obstet Biol Reprod (Paris); 2005 Feb;34(1 Pt 1):85-9
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  • We report a case of a primary uterine choriocarcinoma associated with adenocarcinoma occurring during peri-menopausal age, and review the literature.
  • BHCG and analysis of uterine curettage provided the diagnosis of choriocarcinoma.
  • Histopathologic examination of the surgical specimen revealed only adenocarcinoma.

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  • (PMID = 15767921.001).
  • [ISSN] 0368-2315
  • [Journal-full-title] Journal de gynécologie, obstétrique et biologie de la reproduction
  • [ISO-abbreviation] J Gynecol Obstet Biol Reprod (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 22
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41. Tanaka S, Kubota D, Lee SH, Oba K, Yamamoto T, Ikebe T, Kubo S, Matsuyama M: Latent gallbladder carcinoma in a young adult patient with acute cholecystitis: report of a case. Surg Today; 2007;37(8):713-5
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  • Moreover, a definitive preoperative diagnosis is difficult.
  • The preoperative diagnosis of gallstone-induced acute cholecystitis was made and an open cholecystectomy was thus performed 2 days after admission.
  • Histologic examinations revealed well-differentiated focal adenocarcinoma in the gallbladder mucosa, but no venous, lymphatic, or perineural invasion.

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  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
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42. Heinroth S, Bilkenroth U, Eckert AW, Maurer P: [Bone metastases in the maxilla as first manifestation of renal cell cancer. A case report]. Mund Kiefer Gesichtschir; 2006 Jan;10(1):42-5
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  • In many cases finding the primary tumour is difficult because of its occult location.
  • The first histological and clinical diagnosis revealed a granuloma pyogenicum.
  • Diagnostic procedures detected an adenocarcinoma of the left kidney with pelvic metastases.
  • CONCLUSION: The present case report demonstrates how difficult it can be to provide the right pathological diagnosis in biopsy material even regarding obvious malignancy.
  • [MeSH-major] Carcinoma, Renal Cell / secondary. Kidney Neoplasms / diagnosis. Maxillary Neoplasms / secondary
  • [MeSH-minor] Biopsy, Fine-Needle. Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Bone Neoplasms / secondary. Bone Neoplasms / therapy. Combined Modality Therapy. Diagnosis, Differential. Disease Progression. Female. Humans. Kidney / pathology. Maxilla / pathology. Middle Aged. Pelvic Neoplasms / diagnosis. Pelvic Neoplasms / pathology. Pelvic Neoplasms / secondary. Pelvic Neoplasms / therapy

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  • (PMID = 16402238.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
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43. Buc E, Lesurtel M, Belghiti J: Is preoperative histological diagnosis necessary before referral to major surgery for cholangiocarcinoma? HPB (Oxford); 2008;10(2):98-105
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  • [Title] Is preoperative histological diagnosis necessary before referral to major surgery for cholangiocarcinoma?
  • When imaging techniques fail to establish the accurate diagnosis, biopsy of the lesion is unavoidable.
  • Systematic biopsy is usually difficult and has poor sensitivity, but a good knowledge of these mimicking ECC diseases, along with precise analysis of clinical and imaging semiology, may lead to a correct diagnosis without the need for biopsy.
  • The lack of the primary site, a relatively large tumour size and ancillary findings such as bile duct dilatation may provide a clue to the diagnosis.
  • If not, we advocate local resection with lymph node dissection, since ICC is the most likely diagnosis and surgery is the only curative treatment.
  • In the event of adenocarcinoma from unknown primary, surgery is an effective treatment even if prognosis is poor.

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  • (PMID = 18773064.001).
  • [ISSN] 1365-182X
  • [Journal-full-title] HPB : the official journal of the International Hepato Pancreato Biliary Association
  • [ISO-abbreviation] HPB (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2504385
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44. Lam WW, Chu WC, Tse GM, Ma TK, Tang AP: Role of fine needle aspiration and tru cut biopsy in diagnosis of mucinous carcinoma of breast--from a radiologist's perspective. Clin Imaging; 2006 Jan-Feb;30(1):6-10
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  • [Title] Role of fine needle aspiration and tru cut biopsy in diagnosis of mucinous carcinoma of breast--from a radiologist's perspective.
  • This study was to assess whether fine needle aspiration (FNA) or core biopsy would allow diagnosis of mucinous carcinoma of breast.
  • FNA achieved a sensitivity of 66.7% in diagnosis of malignant lesions and 56% sensitivity in diagnosis of mucinous carcinoma.
  • Core biopsy achieved 100% sensitivity and accuracy in the diagnosis of malignant lesions and mucinous carcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Biopsy / methods. Biopsy, Fine-Needle. Breast Neoplasms / diagnosis

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  • (PMID = 16377477.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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45. Pantanowitz L, Otis CN: Cystitis glandularis. Diagn Cytopathol; 2008 Mar;36(3):181-2
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  • The cytologic finding of glandular cells in a urine specimen is unusual.
  • The differential diagnosis ranges from benign conditions such as cystitis glandularis to adenocarcinoma.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Choristoma / diagnosis. Cytodiagnosis. Diagnosis, Differential. Endometriosis / diagnosis. Female. Humans. Metaplasia. Urinalysis. Urinary Bladder Fistula / diagnosis. Urinary Bladder Neoplasms / diagnosis. Urine / cytology

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  • (PMID = 18232007.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Yousem SA: Pulmonary intestinal-type adenocarcinoma does not show enteric differentiation by immunohistochemical study. Mod Pathol; 2005 Jun;18(6):816-21
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  • [Title] Pulmonary intestinal-type adenocarcinoma does not show enteric differentiation by immunohistochemical study.
  • Six cases of an unusual variant of primary pulmonary adenocarcinoma resembling colorectal and sinonasal adenocarcinoma are presented.
  • Pulmonary intestinal-type adenocarcinoma occurs in elderly Caucasians and is associated with a histology characteristic of colorectal/enteric adenocarcinoma: a garland-like architecture with a 'gland in gland' periphery, central 'dirty' necrosis, and elongated stratified columnar cells, lacking significant goblet or signet ring differentiation.
  • While a resemblance to intestinal adenocarcinoma by light microscopy is present, immunohistochemical studies comparing these carcinomas with metastatic colorectal adenocarcinoma clearly show a respiratory phenotype with the neoplastic cells expressing thyroid transcription factor-1 and cytokeratin 7 to the exclusion of cytokeratin 20, and failing to express CDX-2.
  • The differential diagnosis with other pulmonary adenocarcinomas, especially those with mucinous differentiation, is discussed.
  • [MeSH-major] Adenocarcinoma / pathology. Colonic Neoplasms / pathology. Lung Neoplasms / pathology

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  • (PMID = 15605076.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / Intermediate Filament Proteins; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 0 / MUC2 protein, human; 0 / MUC5AC protein, human; 0 / Mucin 5AC; 0 / Mucin-1; 0 / Mucin-2; 0 / Mucins; 0 / Nuclear Proteins; 0 / Trans-Activators; 0 / Transcription Factors; 0 / thyroid nuclear factor 1; 156560-97-3 / Cdx-2-3 protein; 68238-35-7 / Keratins
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47. Ozer N, Deveci OS, Okutucu S, Demircin M: Asymptomatic right atrial myxoma originating from the inferior vena cava and right atrium junction in a patient with breast ductal adenocarcinoma. Turk Kardiyol Dern Ars; 2009 Oct;37(7):479-82
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  • [Title] Asymptomatic right atrial myxoma originating from the inferior vena cava and right atrium junction in a patient with breast ductal adenocarcinoma.
  • We present asymptomatic right atrial myxoma in a patient with breast ductal adenocarcinoma.
  • She had a 10-month history of modified radical mastectomy for ductal adenocarcinoma of the breast, followed by adjuvant chemotherapy.
  • The tumor was completely excised and histopathologic diagnosis was myxoma.
  • [MeSH-major] Adenocarcinoma / complications. Breast Neoplasms / complications. Carcinoma, Ductal / complications. Heart Atria / pathology. Heart Neoplasms / complications. Myxoma / complications. Vena Cava, Inferior / pathology

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  • (PMID = 20098042.001).
  • [ISSN] 1016-5169
  • [Journal-full-title] Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır
  • [ISO-abbreviation] Turk Kardiyol Dern Ars
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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48. Mackenzie RP, McCollum AD: Novel agents for the treatment of adenocarcinoma of the pancreas. Expert Rev Anticancer Ther; 2009 Oct;9(10):1473-85
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  • [Title] Novel agents for the treatment of adenocarcinoma of the pancreas.
  • Pancreatic cancer is a particularly challenging malignancy, given its usually advanced stage at diagnosis and its rather limited treatment options.
  • A better understanding of the biology of the disease at the basic science level, and epidemiology and risk factors from a public-health perspective, are needed.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Agents / therapeutic use. Pancreatic Neoplasms / drug therapy

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  • (PMID = 19828009.001).
  • [ISSN] 1744-8328
  • [Journal-full-title] Expert review of anticancer therapy
  • [ISO-abbreviation] Expert Rev Anticancer Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
  • [Number-of-references] 111
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49. Zeng L, Kyprianou N: Apoptotic regulators in prostatic intraepithelial neoplasia (PIN): value in prostate cancer detection and prevention. Prostate Cancer Prostatic Dis; 2005;8(1):7-13
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  • [Title] Apoptotic regulators in prostatic intraepithelial neoplasia (PIN): value in prostate cancer detection and prevention.
  • Early diagnosis of prostate cancer holds tremendous promise for the effective therapy and impact on survival of prostate cancer patients.
  • High-grade prostatic intraepithelial neoplasia (HGPIN) is generally accepted as a lesion indicative of a late pathological event in the premalignant changes leading to full development of prostate cancer.
  • Comparative dissection of the apoptosis status and expression profile of key apoptotic regulators among foci of highly proliferative benign prostatic epithelium, PIN and prostate adenocarcinoma from adjacent areas of the same gland revealed a novel insight into the dysfunctional apoptosis events contributing to prostate carcinogenesis.
  • Recent evidence on the molecular changes in apoptosis regulators contributing to HGPIN and their role as molecular markers of disease onset, as well as candidates for therapeutic targeting/chemoprevention of prostate cancer in its early stages will be discussed.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Apoptosis. Biomarkers / analysis. Prostatic Intraepithelial Neoplasia / diagnosis. Prostatic Intraepithelial Neoplasia / pathology. Prostatic Neoplasms / diagnosis. Prostatic Neoplasms / pathology
  • [MeSH-minor] Cell Proliferation. Cell Transformation, Neoplastic. Diagnosis, Differential. Growth Substances. Humans. Male. Physical Examination. Prognosis. Prostate-Specific Antigen / analysis. Rectum. Signal Transduction

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  • (PMID = 15477876.001).
  • [ISSN] 1365-7852
  • [Journal-full-title] Prostate cancer and prostatic diseases
  • [ISO-abbreviation] Prostate Cancer Prostatic Dis.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK-53525-05
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Growth Substances; EC 3.4.21.77 / Prostate-Specific Antigen
  • [Number-of-references] 84
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50. Bandyopadhyay S, Adrean SD, Puklin JE, Feng J: Choroidal metastasis from an occult primary diagnosed by fine-needle aspiration: a case report. Diagn Cytopathol; 2009 Jan;37(1):38-41
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  • We described fine needle aspiration biopsy (FNAB) of a choroidal mass for diagnosis and determining the primary site.
  • The diagnosis of metastatic adenocarcinoma was rendered.
  • [MeSH-major] Adenocarcinoma / secondary. Choroid Neoplasms / secondary. Eye / pathology. Lung Neoplasms / pathology

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18973116.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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51. Chen M, Xu Y, Hao X, Zhang Y, Xu W, Lu B: [The significance of serum sexual hormones' level in male patients with lung cancer]. Zhongguo Fei Ai Za Zhi; 2005 Aug 20;8(4):300-3
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  • BACKGROUND: Many researches indicate that endocrine imbalance plays an important role in the oncogenesis and development of malignant tumor.
  • METHODS: RIA and IRMA were used to detect the levels of serum estrodiol (E₂ ), testosterone (T), prolactin (PRL), growth hormone (GH), luteinizing hormone (LH), follicle-stimulating hormone(FSH) and thyroid-stimulating hormone (TSH) in 62 lung cancer patients, 30 benign pulmonary disease patients and 30 healthy men.
  • RESULTS: The level of T in male patients with lung cancer was obviously lower than that in healthy men (t=0.348, P < 0.01 ); the levels of E₂, PRL and FSH remarkably increased in male patients with lung cancer compared with healthy men (t=0.362, P < 0.01; t=2.913, P < 0.05; t=2.739, P < 0.01); the level of T in male patients with lung cancer was obviously lower than that in patients with benign pulmonary diseases (t= 3.903 , P < 0.05 ); the levels of T in squamous cell carcinoma group and adenocarcinoma group decreased significantly compared with small cell lung cancer group (t=0.358, P < 0.01; t=3.902, P < 0.05).
  • The levels of FSH and TSH in squamous cell carcinoma group were significantly higher than those in adenocarcinoma group (t= 3.918, P < 0.01; t=2.912, P < 0.05).
  • The detection of serum E₂ , T, PRL and FSH may have some value to lung cancer diagnosis and can be an index to predict the state of lung cancer.

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  • (PMID = 21108886.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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52. Tsuji S, Tsuura Y, Morohoshi T, Shinohara T, Oshita F, Yamada K, Kameda Y, Ohtsu T, Nakamura Y, Miyagi Y: Secretion of intelectin-1 from malignant pleural mesothelioma into pleural effusion. Br J Cancer; 2010 Aug 10;103(4):517-23
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  • [Title] Secretion of intelectin-1 from malignant pleural mesothelioma into pleural effusion.
  • BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare but fatal tumour.
  • RESULTS: Malignant pleural mesothelioma cell lines, but not lung adenocarcinoma cell lines, secreted intelectin-1.
  • In immunohistochemistry, epithelioid-type MPMs, but neither pleura-invading lung adenocarcinomas nor reactive mesothelial cells near the lung adenocarcinomas, were stained with anti-intelectin antibodies.
  • CONCLUSION: These results suggest that detection of intelectin-1 may be useful for a differential diagnosis of epithelioid-type MPM in immunohistochemistry and that a high concentration of intelectin-1 in pleural effusion can be used as a new marker for clinical diagnosis of MPM.
  • [MeSH-major] Biomarkers, Tumor / secretion. Cytokines / secretion. Lectins / secretion. Mesothelioma / secretion. Pleural Effusion, Malignant / metabolism. Pleural Neoplasms / secretion

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  • (PMID = 20628387.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cytokines; 0 / GPI-Linked Proteins; 0 / ITLN1 protein, human; 0 / Lectins
  • [Other-IDs] NLM/ PMC2939784
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53. Srikureja W, Chang KJ: Endoscopic palliation of pancreatic adenocarcinoma. Curr Opin Gastroenterol; 2005 Sep;21(5):601-5
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  • [Title] Endoscopic palliation of pancreatic adenocarcinoma.
  • PURPOSE OF REVIEW: Endoscopic therapies have become an indispensable modality in the treatment and palliation of complications from pancreatic adenocarcinoma.
  • This review focuses on treatment of biliary obstruction, malignant gastric outlet obstruction, and intractable abdominal pain resulting from unresectable pancreatic adenocarcinoma.
  • SUMMARY: The frontier of endoscopic palliative therapies for pancreatic adenocarcinoma is expanding.
  • [MeSH-major] Adenocarcinoma / surgery. Endoscopy, Gastrointestinal. Palliative Care / methods. Pancreatic Neoplasms / surgery

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  • (PMID = 16093777.001).
  • [ISSN] 0267-1379
  • [Journal-full-title] Current opinion in gastroenterology
  • [ISO-abbreviation] Curr. Opin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 32
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54. Zell JA, Ou SH, Ziogas A, Anton-Culver H: Long-term survival differences for bronchiolo-alveolar carcinoma patients with ipsilateral intrapulmonary metastasis at diagnosis. Ann Oncol; 2006 Aug;17(8):1255-62
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  • [Title] Long-term survival differences for bronchiolo-alveolar carcinoma patients with ipsilateral intrapulmonary metastasis at diagnosis.

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  • (PMID = 16766595.001).
  • [ISSN] 0923-7534
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
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55. Walter B, Poth T, Böhmer E, Braun J, Matis U: Uterine disorders in 59 rabbits. Vet Rec; 2010 Feb 20;166(8):230-3
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  • Forty-five rabbits underwent ovariohysterectomy and the other 14 rabbits were euthanased, three because of pulmonary metastases and 11 because of very poor health unrelated to their uterine disease.
  • Endometrial hyperplasia (in 24 rabbits) and adenocarcinoma (in 18 rabbits) were the most common uterine disorders; in a further 11 cases both conditions were observed.
  • Four rabbits that were presented with adenocarcinoma of the mammary gland were found to have concurrent uterine disorders.
  • The mean age of the rabbits with endometrial hyperplasia was 4.5 years, and that of the rabbits with adenocarcinoma was 6.1 years.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / veterinary. Animals. Endometrial Hyperplasia / diagnosis. Endometrial Hyperplasia / veterinary. Female. Genitalia, Female / pathology. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / veterinary. Rabbits. Retrospective Studies. Uterine Neoplasms / diagnosis. Uterine Neoplasms / veterinary

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  • (PMID = 20173107.001).
  • [ISSN] 2042-7670
  • [Journal-full-title] The Veterinary record
  • [ISO-abbreviation] Vet. Rec.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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56. Farrell T, Chang YL: Basal cell adenocarcinoma of minor salivary glands. Arch Pathol Lab Med; 2007 Oct;131(10):1602-4
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  • [Title] Basal cell adenocarcinoma of minor salivary glands.
  • Basal cell adenocarcinoma of minor salivary glands is a relatively rare slow-growing tumor with an infiltrating growth pattern.
  • The infiltrating growth pattern and likelihood of vascular and perineural involvement distinguishes basal cell adenocarcinoma from basal cell adenoma.
  • Basal cell adenocarcinomas show strong immunoreactivity to cytokeratin 7 and variable myoepithelial staining with S100.
  • It is necessary to differentiate basal cell adenocarcinoma from other basaloid cell tumors of the minor salivary glands because of the prognosis and potential differences in treatment, particularly adenoid cystic adenocarcinoma and basaloid squamous carcinoma.
  • Surgical excision with a wide margin to ensure complete removal has been suggested as the primary treatment for basal cell adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Salivary Gland Neoplasms / diagnosis. Salivary Glands, Minor / pathology
  • [MeSH-minor] Adenoma / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Squamous Cell / diagnosis. Combined Modality Therapy. Diagnosis, Differential. Humans

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  • (PMID = 17922602.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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57. Boldrini L, Gisfredi S, Ursino S, Camacci T, Baldini E, Melfi F, Fontanini G: Mutational analysis in cytological specimens of advanced lung adenocarcinoma: a sensitive method for molecular diagnosis. J Thorac Oncol; 2007 Dec;2(12):1086-90
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  • [Title] Mutational analysis in cytological specimens of advanced lung adenocarcinoma: a sensitive method for molecular diagnosis.
  • INTRODUCTION: The discovery that somatic mutations in the epidermal growth factor receptor (EGFR) gene are associated with sensitivity to the EGFR tyrosine kinase inhibitors (TKIs) in lung adenocarcinomas, whereas Kras mutations are associated with resistance, has generated excitement among both clinicians and researchers studying non-small cell lung cancer (NSCLC).
  • METHODS: We analyzed 23 archived cytologic specimens of advanced/metastatic lung adenocarcinomas for mutations in EGFR exons 18 to 21, and Kras exon 2.
  • Kras mutations involving codon 12 in exon 2 were found in 5 (21.73%) of the 23 adenocarcinomas and were associated, where known, with smoking habits.
  • [MeSH-major] Adenocarcinoma / genetics. DNA Mutational Analysis. Genes, erbB-1. Lung Neoplasms / genetics
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Chi-Square Distribution. DNA, Neoplasm / analysis. Feasibility Studies. Female. Genetic Predisposition to Disease. Humans. Male. Middle Aged. Molecular Biology. Mutation. Neoplasm Invasiveness / genetics. Neoplasm Invasiveness / pathology. Neoplasm Staging. Polymorphism, Restriction Fragment Length. Probability. Sensitivity and Specificity. Tissue Culture Techniques

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  • (PMID = 18090579.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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58. Liu YY, Morreau H, Kievit J, Romijn JA, Carrasco N, Smit JW: Combined immunostaining with galectin-3, fibronectin-1, CITED-1, Hector Battifora mesothelial-1, cytokeratin-19, peroxisome proliferator-activated receptor-{gamma}, and sodium/iodide symporter antibodies for the differential diagnosis of non-medullary thyroid carcinoma. Eur J Endocrinol; 2008 Mar;158(3):375-84
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  • [Title] Combined immunostaining with galectin-3, fibronectin-1, CITED-1, Hector Battifora mesothelial-1, cytokeratin-19, peroxisome proliferator-activated receptor-{gamma}, and sodium/iodide symporter antibodies for the differential diagnosis of non-medullary thyroid carcinoma.
  • OBJECTIVES: The microscopic distinction between benign and malignant thyroid lesions in clinical practice is still largely based on conventional histology.
  • METHODS: We used tissue arrays containing 177 thyroid tissues: 100 benign tissues (including normal thyroid, Graves disease, multinodular goiter, and follicular adenoma (FA)) and 77 thyroid carcinomas (including papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, and follicular variant of PTC (FVPTC)).
  • RESULTS: In general, we found overexpression of FN-1, CITED-1, Gal-3, CK-19, HBME-1, and iNIS in malignant thyroid lesions.
  • Gal-3, FN-1, and iNIS had the highest accuracy in the differential diagnosis of follicular lesions.
  • A panel of Gal-3, FN-1, and iNIS, identified by hierarchical cluster analysis, had a 98% accuracy to differentiate between FA and malignant thyroid lesions.
  • CONCLUSION: We conclude that identifying optimal antibody panels with cluster analysis increases the diagnostic value in the differential diagnosis of thyroid neoplasms, the combination of FN-1, Gal-3, and iNIS having the best accuracy (98%).

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  • (PMID = 18299472.001).
  • [ISSN] 1479-683X
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies; 0 / Biomarkers, Tumor; 0 / CITED1 protein, human; 0 / Fibronectins; 0 / Galectin 3; 0 / HBME-1 antigen; 0 / Keratin-19; 0 / Nuclear Proteins; 0 / PPAR gamma; 0 / Symporters; 0 / Transcription Factors; 0 / sodium-iodide symporter
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59. Yango J, Pieters T, Coche E, Lambert M: [Increased serum CA 19.9 in bronchiectasis]. Rev Mal Respir; 2008 Jan;25(1):78-81
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  • INTRODUCTION: CA 19.9 is considered the most specific and sensitive serological marker of pancreatic adenocarcinoma.
  • Exhaustive investigation and clinical evolution excluded a neoplastic digestive disorder but positron emission tomography revealed a distinct hypermetabolic focus in the area of the hilum of the right lung.
  • [MeSH-major] Bronchiectasis / diagnosis. CA-19-9 Antigen / blood
  • [MeSH-minor] Aged. Biomarkers / blood. Female. Haemophilus Infections / diagnosis. Haemophilus Infections / immunology. Haemophilus influenzae / immunology. Haemophilus influenzae / isolation & purification. Humans

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  • (PMID = 18288056.001).
  • [ISSN] 0761-8425
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers; 0 / CA-19-9 Antigen
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60. Arévalo Novoa JF, Díaz Pérez JA, Ferreira Bohórquez EJ, Puentes Vega NJ: [Colonic primary lipoma simulator of an adenocarcinoma]. Rev Esp Enferm Dig; 2009 Aug;101(8):589-91
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  • [Title] [Colonic primary lipoma simulator of an adenocarcinoma].
  • [Transliterated title] Lipoma primario del colon simulador de un adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Colonic Neoplasms / diagnosis. Lipoma / diagnosis
  • [MeSH-minor] Abdominal Pain / etiology. Adult. Colectomy. Colon / pathology. Colonoscopy. Diagnosis, Differential. Female. Humans. Melena / etiology. Radiography, Abdominal. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19785504.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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61. Chua TC, Pelz JO, Kerscher A, Morris DL, Esquivel J: Critical analysis of 33 patients with peritoneal carcinomatosis secondary to colorectal and appendiceal signet ring cell carcinoma. Ann Surg Oncol; 2009 Oct;16(10):2765-70
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  • The majority of patients develop peritoneal carcinomatosis (PC) early in the disease.
  • RESULTS: Thirty-three patients (18 women (55%); mean age at diagnosis of carcinomatosis, 49 (standard deviation = 12) years) were identified to have SRC, with 15 cases of colorectal and 18 of appendiceal origin.
  • CONCLUSIONS: There seems to be less survival benefits after a complete CRS and HIPEC as a curative treatment for PC from colorectal SRC compared with that for non-SRC colorectal adenocarcinoma.
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Female. Follow-Up Studies. Humans. Hyperthermia, Induced. Male. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Survival Rate. Treatment Outcome


62. Ismiil N, Ghorab Z, Covens A, Nofech-Mozes S, Saad R, Dubé V, Khalifa MA: Intraoperative margin assessment of the radical trachelectomy specimen. Gynecol Oncol; 2009 Apr;113(1):42-6
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  • Surgeries were performed for clinical Stages 1A (n=39) and 1B (n=93) tumors (63 adenocarcinoma, 59 squamous cell carcinoma, 7 adenosquamous and 3 others).
  • Final margin assessment agreed with the FS diagnosis in 130 (98.5%) and showed interpretational overcall in 2 cases (1.5%); only one of which resulted in a revised margin.
  • [MeSH-minor] Adolescent. Adult. Female. Frozen Sections. Gynecologic Surgical Procedures / methods. Humans. Intraoperative Period / methods. Middle Aged. Neoplasm Staging. Young Adult


63. Sano D, Matsuda H, Yoshida T, Kimura Y, Tanigaki Y, Mikami Y, Tsukuda M: A case of metastatic colon adenocarcinoma in the larynx. Acta Otolaryngol; 2005 Feb;125(2):220-2
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  • [Title] A case of metastatic colon adenocarcinoma in the larynx.
  • We report a case of metastatic laryngeal tumor originating from a colon adenocarcinoma in an 81-year-old female.
  • The diagnosis, route of metastasis, treatment and prognosis of metastatic laryngeal tumors are discussed.
  • [MeSH-major] Adenocarcinoma / secondary. Colonic Neoplasms / pathology. Colonic Neoplasms / surgery. Laryngeal Neoplasms / secondary. Laryngeal Neoplasms / surgery

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  • (PMID = 15880957.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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64. Stolnicu S, Preda O, Dohan M, Puscasiu L, García-Galvis OF, Nogales FF: Pseudoglandular hepatoid differentiation in endometrioid carcinoma of the ovary simulates oxyphilic cell change. Int J Gynecol Pathol; 2008 Oct;27(4):521-5
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  • A 42-year-old patient had a stage III ovarian endometrioid adenocarcinoma with areas of hepatoid carcinoma (HC) of clear cell and eosinophilic pseudoglandular type that was difficult to differentiate from endometrioid carcinoma of oxyphilic type and sex cord-stromal tumor.
  • Immunohistochemically, endometrioid adenocarcinoma was positive for CA125, estrogen and progesterone receptors, CAM5.2, cytokeratin (CK) 7 and 19, and vimentin.
  • In the differential diagnosis, a hepatic immunophenotype of oxyphilic, mitochondriae-rich areas (demonstrated by antimitochondrial antibodies) was identified by HC specific (hep par1) and characteristic markers: canalicular, cytoplasmic and membranous polyclonal carcinoembryonic antigens, CD10 patterns, and alpha-fetoprotein).

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  • (PMID = 18753970.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Patel V, Castell FA, Akinwunmi J, Francis I, Chandrasekharan L, Malhotra R: Prostatic adenocarcinoma presenting with metastatic frontal bone involvement and orbital invasion. Orbit; 2010 Aug;29(4):213-5
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  • [Title] Prostatic adenocarcinoma presenting with metastatic frontal bone involvement and orbital invasion.
  • We present a rare case of prostatic adenocarcinoma presenting with metastatic frontal bone involvement with subsequent spread to the orbit.
  • Although prostatic adenocarcinoma has a strong tendency to metastasize to bone, particularly axial skeletal bone, frontal bone involvement is rare and subsequent orbital involvement is even more so.
  • [MeSH-major] Adenocarcinoma / secondary. Neoplasm Invasiveness / pathology. Orbital Neoplasms / secondary. Orbital Neoplasms / surgery. Prostate-Specific Antigen / blood. Prostatic Neoplasms / pathology
  • [MeSH-minor] Aged. Antineoplastic Agents, Hormonal / therapeutic use. Biopsy, Needle. Diagnosis, Differential. Follow-Up Studies. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Neoplasm Staging. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20812840.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; EC 3.4.21.77 / Prostate-Specific Antigen
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66. Manfredi R, Sabbatani S, Fasulo G: HIV-associated early gastric adenocarcinoma successfully cured with surgery, and followed over eight years. Int J STD AIDS; 2007 Jul;18(7):501-4
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  • [Title] HIV-associated early gastric adenocarcinoma successfully cured with surgery, and followed over eight years.
  • An extremely rare case report of HIV-associated gastric adenocarcinoma surgically treated in the year 1998 in a 37-year-old male patient already HIV positive for 10 years, with a complete post-surgery disease-free follow-up of eight years, is described.
  • Seven occurred prior to the introduction of highly active antiretroviral therapy (HAART) and were burdened by a rapid disease evolution, while only two patients were reported after the introduction of HAART (like ours) and obtained surgical cure.
  • Notably, even four of the nine published reports came from Japan, and an early disease development was usual (37-50 years of age at diagnosis).
  • Due to its relevant differential diagnosis implications with many other HIV-related gastrointestinal disturbances caused by functional and organic diseases (drug-related disturbances, HIV infection itself, opportunistic infections, and Kaposi's sarcoma and malignant lymphomas being the most frequent disorders) and the possibility of maintaining an adequate life-expectancy when diagnosis and aggressive treatment are not delayed, gastric cancer should be considered carefully by all clinicians dealing with HIV disease.
  • [MeSH-major] Adenocarcinoma / virology. Antiretroviral Therapy, Highly Active. HIV Infections / complications. HIV Infections / drug therapy. Stomach Neoplasms / virology


67. Pera M, Grande L, Iglesias M, Ramón JM, Conio M: [New advances in the diagnosis and treatment of early onset dysplasia and adenocarcinoma in Barrett's oesophagus]. Cir Esp; 2009 Jun;85(6):331-40
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  • [Title] [New advances in the diagnosis and treatment of early onset dysplasia and adenocarcinoma in Barrett's oesophagus].
  • [Transliterated title] Nuevos avances en el diagnóstico y el tratamiento de la displasia y el adenocarcinoma precoz en el esófago de Barrett.
  • Periodic endoscopic follow-up is recommended after the diagnosis of Barrett's oesophagus, particularly in patients with dysplasia.
  • The new endoscopic techniques show promising results in identifying areas suspected of housing high grade dysplasia and adenocarcinoma.
  • Likewise, this technique may be the therapeutic option in patients with high grade dysplasia and adenocarcinoma, although its application must be complemented with ablation techniques such as radiofrequency to eliminate the residual Barrett's metaplasia.
  • Oesophagectomy associated with lymphadenectomy is the option of choice in patients with submucosal adenocarcinoma.
  • The diagnosis and treatment of patients with early onset high grade dysplasia and adenocarcinoma must be carried out with multidisciplinary teams who can evaluate each case individually.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Barrett Esophagus / complications. Esophageal Neoplasms / diagnosis. Esophageal Neoplasms / surgery. Esophagus / pathology

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  • (PMID = 19463990.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Spain
  • [Number-of-references] 71
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68. Yoshimitsu K, Irie H, Aibe H, Tajima T, Nishie A, Asayama Y, Matake K, Yamaguchi K, Matsuura S, Honda H: Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production: a mimicker of adenomyomatosis. Eur Radiol; 2005 Feb;15(2):229-33
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  • [Title] Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production: a mimicker of adenomyomatosis.
  • They were all well-differentiated adenocarcinomas, and the cystic components consisted of dilated neoplastic glands filled with abundant mucin pool.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Gallbladder Neoplasms / pathology. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Adenomyoma / pathology. Adult. Aged. Diagnosis, Differential. Female. Humans. Japan / epidemiology. Male. Middle Aged. Prevalence. Retrospective Studies. Statistics, Nonparametric

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  • (PMID = 15662477.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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69. Rho JH, Roehrl MH, Wang JY: Glycoproteomic analysis of human lung adenocarcinomas using glycoarrays and tandem mass spectrometry: differential expression and glycosylation patterns of vimentin and fetuin A isoforms. Protein J; 2009 May;28(3-4):148-60
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  • [Title] Glycoproteomic analysis of human lung adenocarcinomas using glycoarrays and tandem mass spectrometry: differential expression and glycosylation patterns of vimentin and fetuin A isoforms.
  • Advances in pathophysiologic understanding and novel biomarkers for diagnosis and treatment are significant tasks.
  • We have undertaken a comprehensive glycoproteomic analysis of human lung adenocarcinoma tissues.
  • Glycoproteins from paired lung adenocarcinoma and normal tissues were enriched by the lectins Con A, WGA, and AIL.
  • In particular, the discovery of differentially glycosylated protein isoforms in lung adenocarcinoma may represent avenues towards new functional biomarkers for diagnosis, treatment guidance, and response monitoring.
  • [MeSH-minor] Adenocarcinoma / chemistry. Adenocarcinoma / metabolism. Blood Proteins / analysis. Blood Proteins / metabolism. Electrophoresis, Gel, Two-Dimensional. Glycosylation. Humans. Proteomics / methods. RNA, Messenger / analysis. Vimentin / analysis. Vimentin / metabolism. alpha-2-HS-Glycoprotein


70. Zhou M, Zhu Y, Wang L, Wang Y, Fu S, Min Z: Urological malignancy as a complication of renal transplantation: a report of twelve clinical cases. Clin Transpl; 2006;:395-8
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  • RESULTS: Of the 3150 recipients, 33 (1.05%) developed malignancies, including 12 patients (0.38%; eight males and four females) with urological tumors and 21 patients with skin carcinoma, right liver lobular cystic adenocarcinoma, hepatocellular carcinoma, gastric cancer, colorectal carcinoma, ileocecal adenoma, lip cancer, nasopharyngeal carcinoma, Kaposi's Sarcoma, pulmonary lymphoma, and breast cancer.
  • The age at which the diagnosis was made ranged from 48 to 66 years with a mean of 58.3 +/- 4.6 years, and the mean course of immunosuppressive therapy ranged from 26 to 120 months with a mean of 62 +/- 18 months.
  • One of the 12 patients died soon after the diagnosis was made, and the remaining 11 patients received surgical resection.
  • Treatment includes early diagnosis, timely surgical resection, and reduction of immunosuppressive agents.

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  • (PMID = 18365395.001).
  • [ISSN] 0890-9016
  • [Journal-full-title] Clinical transplants
  • [ISO-abbreviation] Clin Transpl
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
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71. Arfaoui Toumi A, Kriaa Ben Mahmoud L, Khiari M, Lahmer A, Gharbi L, Dhraïef M, Khalfallah T, Regaya Mzabi S, Bouraoui S: [Epidemiological study, pathologic evaluation and prognostic factors of colorectal mucinous vs non-mucinous adenocarcinoma (a series of 196 patients)]. Tunis Med; 2010 Jan;88(1):12-7
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  • [Title] [Epidemiological study, pathologic evaluation and prognostic factors of colorectal mucinous vs non-mucinous adenocarcinoma (a series of 196 patients)].
  • [Transliterated title] Etude épidémiologique, anatomopathologique et évaluation des facteurs pronostiques des adénocarcinomes colorectaux mucineux vs non mucineux. (A propos d'une série de 196 patients).
  • BACKGROUND: Colorectal carcinoma is one of the main causes of cancer death in the worldwide with a decrease survival rate in relationship with a later diagnosis of advanced disease.
  • Age at diagnosis, mode of presentation, sex, tumour location, macroscopic and histological features, TNM and Astler Coller stage were assessed and evaluated.
  • The poorer degree of differentiation and mucinous subtype are correlated with an advanced stage.
  • Furthermore, immunohistochemical analysis of galectin-3 showed a significant difference between mucinous and non mucinous adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Adenocarcinoma, Mucinous / epidemiology. Adenocarcinoma, Mucinous / pathology. Biomarkers, Tumor / analysis. Colorectal Neoplasms / epidemiology. Colorectal Neoplasms / pathology. Galectin 3 / analysis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Colon, Sigmoid / pathology. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Prognosis. Prospective Studies. Rectum / pathology. Retrospective Studies. Risk Factors. Survival Analysis. Tunisia / epidemiology

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  • (PMID = 20415207.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Tunisia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Galectin 3
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72. Ramus JR, Gatenby PA, Caygill CP, Winslet MC, Watson A: Surveillance of Barrett's columnar-lined oesophagus in the UK: endoscopic intervals and frequency of detection of dysplasia. Eur J Gastroenterol Hepatol; 2009 Jun;21(6):636-41
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  • OBJECTIVES: Endoscopic surveillance of patients with columnar-lined oesophagus (CLO) may identify those with early adenocarcinoma (AC).
  • We sought to examine surveillance practice for CLO in the UK and the impact of endoscopic intervals on detection of dysplastic disease.
  • Endoscopic intervals were calculated and frequency of detection of dysplastic disease analysed using chi2 test of association.
  • A large proportion of dysplastic disease is detected on specific surveillance endoscopies.
  • [MeSH-major] Adenocarcinoma / diagnosis. Barrett Esophagus / diagnosis. Esophageal Neoplasms / diagnosis. Population Surveillance / methods. Precancerous Conditions / diagnosis
  • [MeSH-minor] Aged. Disease Progression. Early Diagnosis. Esophagoscopy / methods. Female. Great Britain. Humans. Male. Middle Aged. Professional Practice. Registries. Time Factors

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  • (PMID = 19177028.001).
  • [ISSN] 1473-5687
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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73. Wilde BK, Senger JL, Kanthan R: Gastrointestinal schwannoma: an unusual colonic lesion mimicking adenocarcinoma. Can J Gastroenterol; 2010 Apr;24(4):233-6
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  • [Title] Gastrointestinal schwannoma: an unusual colonic lesion mimicking adenocarcinoma.
  • Gastrointestinal schwannoma is a rare, benign pathological entity that can mimic colonic adenocarcinoma and cause diagnostic dilemmas for treatment.
  • A case of a 68-year-old woman with colonic adenocarcinoma who was discovered to have an incidental synchronous bowel lesion that proved to be a gastrointestinal schwannoma and not a synchronous adenocarcinoma is described.
  • Accurate diagnosis and recognition of this benign entity is, therefore, of immense clinicopathological value for accurate planning of therapeutic strategies.
  • [MeSH-major] Adenocarcinoma / diagnosis. Colonic Neoplasms / diagnosis. Neurilemmoma / diagnosis
  • [MeSH-minor] Aged. Biopsy. Colectomy. Colonoscopy. Diagnosis, Differential. Female. Humans. Tomography, X-Ray Computed

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  • (PMID = 20431810.001).
  • [ISSN] 0835-7900
  • [Journal-full-title] Canadian journal of gastroenterology = Journal canadien de gastroenterologie
  • [ISO-abbreviation] Can. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2864617
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74. Scherübl H, Klöppel G: [Rectal carcinoids on the rise - update]. Z Gastroenterol; 2009 Apr;47(4):365-71
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  • In addition to the early detection of colorectal adenoma and adenocarcinoma, screening colonoscopy also makes possible the early detection and early therapy for neuroendocrine rectal tumours/carcinomas.
  • [MeSH-minor] Colonoscopy. Cross-Sectional Studies. Endosonography. Humans. Incidence. Incidental Findings. Intestinal Mucosa / pathology. Malignant Carcinoid Syndrome / diagnosis. Malignant Carcinoid Syndrome / epidemiology. Malignant Carcinoid Syndrome / pathology. Malignant Carcinoid Syndrome / therapy. Mass Screening. Neoplasm Invasiveness / pathology. Prognosis

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  • (PMID = 19358064.001).
  • [ISSN] 0044-2771
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 41
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75. van den Top JG, de Heer N, Klein WR, Ensink JM: Penile and preputial tumours in the horse: a retrospective study of 114 affected horses. Equine Vet J; 2008 Sep;40(6):528-32
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  • Squamous cell carcinoma (SCC) was the most prevalent neoplasm followed by papillomas and melanomas.
  • A basal cell carcinoma, neurofibrosarcoma, adenocarcinoma or fibrosarcoma were each found on single horses.
  • [MeSH-minor] Age Factors. Animals. Breeding. Horses. Lymph Nodes / pathology. Lymph Nodes / surgery. Lymphatic Metastasis / diagnosis. Male. Neoplasm Metastasis / diagnosis. Neoplasm Staging / veterinary. Orchiectomy / veterinary. Papilloma / epidemiology. Papilloma / pathology. Papilloma / surgery. Papilloma / veterinary. Pedigree. Penis / pathology. Penis / surgery. Retrospective Studies. Urethra / pathology. Urethra / surgery

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  • (PMID = 18487101.001).
  • [ISSN] 0425-1644
  • [Journal-full-title] Equine veterinary journal
  • [ISO-abbreviation] Equine Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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76. Takeuchi K, Yokoyama M, Ishizawa S, Terui Y, Nomura K, Marutsuka K, Nunomura M, Fukushima N, Yagyuu T, Nakamine H, Akiyama F, Hoshi K, Matsue K, Hatake K, Oshimi K: Lymphomatoid gastropathy: a distinct clinicopathologic entity of self-limited pseudomalignant NK-cell proliferation. Blood; 2010 Dec 16;116(25):5631-7
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  • Diagnostic errors in distinguishing between malignant and reactive processes can cause serious clinical consequences.
  • Analysis of the 16 specimens biopsied from 10 patients led to a diagnosis of lymphoma or suspected lymphoma in 11 specimens, gastritis for 1 specimen, adenocarcinoma for 1 specimen, and LyGa or suspected LyGa for 3 specimens.
  • [MeSH-minor] Aged. Blotting, Western. Epstein-Barr Virus Infections / diagnosis. Epstein-Barr Virus Infections / genetics. Epstein-Barr Virus Infections / metabolism. Female. Flow Cytometry. Gene Rearrangement. Herpesvirus 4, Human / genetics. Humans. Immunoenzyme Techniques. Immunophenotyping. In Situ Hybridization. Male. Middle Aged. RNA, Messenger / genetics. Receptors, Antigen, T-Cell, alpha-beta / genetics. Receptors, Antigen, T-Cell, alpha-beta / metabolism. Receptors, Antigen, T-Cell, gamma-delta / genetics. Receptors, Antigen, T-Cell, gamma-delta / metabolism. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 20829373.001).
  • [ISSN] 1528-0020
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / Receptors, Antigen, T-Cell, alpha-beta; 0 / Receptors, Antigen, T-Cell, gamma-delta
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77. Shameem M, Akhtar J, Baneen U, Bhargava R, Ahmed Z, Sharma P, Khan NA, Hassan MJ: Primary peritoneal adenocarcinoma causes pleural effusion. N Am J Med Sci; 2010 Jun;2(6):281-4
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  • [Title] Primary peritoneal adenocarcinoma causes pleural effusion.
  • CONTEXT: The most common malignancies associated with malignant pleural effusions are carcinomas of the breast, lung, gastrointestinal tract, ovary and lymphomas.
  • Primary peritoneal adenocarcinoma is a very rare cause of malignant pleural effusion.
  • A cytologic examination of pleural fluid revealed adenocarcinoma cells.
  • A histological examination of a peritoneal lesion was suggestive of adenocarcinoma.
  • CONCLUSIONS: The patient was diagnosed with a rare case of primary peritoneal adenocarcinoma with bilateral pleural effusion.

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  • (PMID = 22574304.001).
  • [ISSN] 1947-2714
  • [Journal-full-title] North American journal of medical sciences
  • [ISO-abbreviation] N Am J Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3347636
  • [Keywords] NOTNLM ; Malignant pleural effusion / primary peritoneal adenocarcinoma
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78. Shields JA, Eagle RC Jr, Shields CL, Brown GC, Lally SE: Malignant transformation of congenital hypertrophy of the retinal pigment epithelium. Ophthalmology; 2009 Nov;116(11):2213-6
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  • [Title] Malignant transformation of congenital hypertrophy of the retinal pigment epithelium.
  • PURPOSE: To report a clinicopathologic correlation of an adenocarcinoma that arose from solitary congenital hypertrophy of the retinal pigment epithelium (CHRPE).
  • It had features typical of CHRPE, but there was a small elevated nodule within the flat component, and the diagnosis was adenoma of the retinal pigment epithelium (RPE) arising from CHRPE.
  • Thirteen years after the initial diagnosis, the patient returned with severe visual loss and no view of the fundus resulting from cataract and posterior synechia.
  • The final diagnosis was adenocarcinoma arising from CHRPE.
  • CONCLUSIONS: Congenital hypertrophy of the retinal pigment epithelium, once considered to be a benign and stationary lesion, may spawn a malignant neoplasm.
  • [MeSH-major] Adenocarcinoma / pathology. Cell Transformation, Neoplastic / pathology. Retinal Neoplasms / pathology. Retinal Pigment Epithelium / pathology

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  • (PMID = 19744732.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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79. Wang GQ, Wei WQ, Zhang JH: [Natural progression of early stage adenocarcinoma of gastric cardia: a report of seventeen cases]. Ai Zheng; 2007 Nov;26(11):1153-6
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  • [Title] [Natural progression of early stage adenocarcinoma of gastric cardia: a report of seventeen cases].
  • BACKGROUND & OBJECTIVE: The survival time of untreated advanced gastric cardiac adenocarcinoma patients is about 8-9 months.
  • This study was to observe the natural progression of untreated early stage gastric cardiac adenocarcinoma.
  • METHODS: In 1987, at a high risk area of esophageal cancer, 851 patients with a previous cytologic diagnosis of esophageal dysplasia were re-examined by endoscopy, and 43 of them were diagnosed histologically as gastric cardiac adenocarcinoma.
  • RESULTS: Of the 17 untreated patients, 12 were died of gastric cardiac adenocarcinoma, 5 were died of non-cancer diseases; 13 had survived for over 5 years.
  • CONCLUSIONS: The progression of early stage cardiac cancer to advanced cancer is a very slow and long process, which is very helpful for early diagnosis and choice of therapeutic timing.
  • The therapeutic effect on early stage cardiac cancer should be assessed with consideration of the natural history of this disease.
  • [MeSH-major] Adenocarcinoma / pathology. Cardia / pathology. Disease Progression. Stomach Neoplasms / pathology
  • [MeSH-minor] Aged. Carcinoma in Situ / pathology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Survival Rate

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  • (PMID = 17991310.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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80. Jatoi A, Dakhil SR, Foster NR, Ma C, Rowland KM Jr, Moore DF Jr, Jaslowski AJ, Thomas SP, Hauge MD, Flynn PJ, Stella PJ, Alberts SR: Bortezomib, paclitaxel, and carboplatin as a first-line regimen for patients with metastatic esophageal, gastric, and gastroesophageal cancer: phase II results from the North Central Cancer Treatment Group (N044B). J Thorac Oncol; 2008 May;3(5):516-20
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  • PURPOSE: This study was undertaken to explore the response rate of a first-line, three-drug regimen that consisted of bortezomib, paclitaxel, and carboplatin in patients with metastatic adenocarcinoma of the esophagus, gastroesophageal junction, or gastric cardia.
  • PATIENTS AND METHODS: Patients with the above diagnosis and acceptable organ function were treated intravenously on a 21-day cycle with the following: bortezomib 1.2 mg/m on days 1, 4, and 8; paclitaxel 175 mg/m on day 2; and carboplatin with an area under the curve of 6 on day 2.

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  • (PMID = 18449005.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U10 CA035267; United States / NCI NIH HHS / CA / U10 CA037417; United States / NCI NIH HHS / CA / N01 CA035431; United States / NCI NIH HHS / CA / U10 CA035269; United States / NCI NIH HHS / CA / CA-37404; United States / NCI NIH HHS / CA / CA-35431; United States / NCI NIH HHS / CA / CA-35090; United States / NCI NIH HHS / CA / U10 CA060276; United States / NCI NIH HHS / CA / CA-35195; United States / NCI NIH HHS / CA / U10 CA037404; United States / NCI NIH HHS / CA / N01 CA035119; United States / NCI NIH HHS / CA / U10 CA063848; United States / NCI NIH HHS / CA / U10 CA035195; United States / NCI NIH HHS / CA / CA-35103; United States / NCI NIH HHS / CA / CA-25224; United States / NCI NIH HHS / CA / CA-60276; United States / NCI NIH HHS / CA / CA-35113; United States / NCI NIH HHS / CA / U10 CA035113; United States / NCI NIH HHS / CA / P30 CA015083; United States / NCI NIH HHS / CA / CA-52654; United States / NCI NIH HHS / CA / CA-63848; United States / NCI NIH HHS / CA / U10 CA063849; United States / NCI NIH HHS / CA / CA-35119; United States / NCI NIH HHS / CA / U10 CA035431; United States / NCI NIH HHS / CA / U10 CA035119; United States / NCI NIH HHS / CA / CA-37417; United States / NCI NIH HHS / CA / CA-35269; United States / NCI NIH HHS / CA / U10 CA052654; United States / NCI NIH HHS / CA / U10 CA025224; United States / NCI NIH HHS / CA / U10 CA035090; United States / NCI NIH HHS / CA / CA-15083; United States / NCI NIH HHS / CA / CA-35267; United States / NCI NIH HHS / CA / CA-63849; United States / NCI NIH HHS / CA / N01 CA015083; United States / NCI NIH HHS / CA / U10 CA035103
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Boronic Acids; 0 / Pyrazines; 69G8BD63PP / Bortezomib; BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
  • [Other-IDs] NLM/ NIHMS547678; NLM/ PMC3929582
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81. Sari YS, Sander E, Erkan E, Tunali V: Endoscopic diagnoses and CLO test results in 9239 cases, prevalence of Helicobacter pylori in Istanbul, Turkey. J Gastroenterol Hepatol; 2007 Nov;22(11):1706-11
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  • BACKGROUND: Helicobacter pylori is implicated in the etiology of gastric and duodenal ulcer, non-ulcer dispepsia, atrophic gastritis, gastric adenocarcinoma and lymphoma.
  • The most frequent endoscopic diagnosis was pangastritis (64%) and non-erosive duodenitis (30.5%).
  • [MeSH-major] Endoscopy, Gastrointestinal. Gastroenteritis / microbiology. Helicobacter Infections / diagnosis. Helicobacter pylori / isolation & purification. Urease / analysis

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  • (PMID = 17914939.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; EC 3.5.1.5 / Urease
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82. Caruso S, Marrelli D, Pedrazzani C, Neri A, Mazzei MA, Onorati M, Corso G, Cerullo G, Roviello F: A rare case of primary small bowel adenocarcinoma with intussusception. Tumori; 2010 Mar-Apr;96(2):355-7
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  • [Title] A rare case of primary small bowel adenocarcinoma with intussusception.
  • We report the case of a 51-year-old man presenting with jejunal intussusception due to a primary adenocarcinoma.
  • Histological examination of the specimen resulted in a diagnosis of a primary adenocarcinoma of the small bowel.
  • [MeSH-major] Adenocarcinoma / complications. Intussusception / etiology. Jejunal Diseases / etiology. Jejunal Neoplasms / complications

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  • (PMID = 20572601.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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83. Brock M, Martin W, Sommerer F, Noldus J: [Ductal Adenocarcinoma of the prostate with infiltration of the bladder. Can radical cystectomy and antiandrogen therapy cure the disease?]. Urologe A; 2009 Jul;48(7):770-3
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  • [Title] [Ductal Adenocarcinoma of the prostate with infiltration of the bladder. Can radical cystectomy and antiandrogen therapy cure the disease?].
  • [Transliterated title] Das duktale Adenokarzinom der Prostata mit Blasenhalsinfiltration. Heilung durch radikale Zystektomie und antiandrogene Therapie?
  • Ductal adenocarcinoma of the prostate is a rare entity.
  • [MeSH-minor] Combined Modality Therapy. Humans. Male. Middle Aged. Neoplasm Invasiveness. Treatment Outcome

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  • (PMID = 19352617.001).
  • [ISSN] 1433-0563
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
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  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Androgen Antagonists
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84. Werder P, Altermatt HJ, Zbären P, Bornstein MM: Canalicular adenoma of a minor salivary gland on the palate: a case presentation. Quintessence Int; 2009 Sep;40(8):623-6
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  • [Title] Canalicular adenoma of a minor salivary gland on the palate: a case presentation.
  • Canalicular adenomas are uncommon, benign epithelial neoplasms of the salivary glands that usually involve the upper lip and buccal mucosa of elderly people.
  • Differential diagnosis of the canalicular adenoma versus adenocarcinoma is important, as it may result in unjustified radiotherapy or extensive and aggressive surgery.
  • Despite the benign nature of canalicular adenomas, complete surgical removal and a regular clinical follow-up are recommended.
  • The present article describes the diagnostic procedures, surgical management, and follow-up of a canalicular adenoma involving the palate of a 71-year-old man.
  • [MeSH-major] Adenoma / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Aged. Diagnosis, Differential. Humans. Laser Therapy. Lasers, Gas / therapeutic use. Male. Palatal Neoplasms / pathology. Palatal Neoplasms / radiography. Palatal Neoplasms / surgery. Palate, Hard / pathology. Palate, Hard / radiography. Palate, Hard / surgery

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  • (PMID = 19639085.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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85. Schäfer C, Rothfuss K, Kreichgauer HP, Stange EF: Efficacy of double-balloon enteroscopy in the evaluation and treatment of bleeding and non-bleeding small bowel disease. Z Gastroenterol; 2007 Mar;45(3):237-43
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  • [Title] Efficacy of double-balloon enteroscopy in the evaluation and treatment of bleeding and non-bleeding small bowel disease.
  • The diagnostic success rate was 51 of 82 (62 %) with a higher rate in bleeders in whom angiodysplasias were the most frequent diagnosis.
  • In 4 patients, malignant neoplasias were newly diagnosed (2 gastrointestinal stroma tumors, 1 neuroendocrine tumor, 1 adenocarcinoma).

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  • (PMID = 17357953.001).
  • [ISSN] 0044-2771
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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91. Xue HD, Li S, Sun F, Sun HY, Jin ZY, Yang JX, Yu M: Clinical application of body diffusion weighted MR imaging in the diagnosis and preoperative N staging of cervical cancer. Chin Med Sci J; 2008 Sep;23(3):133-7
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  • [Title] Clinical application of body diffusion weighted MR imaging in the diagnosis and preoperative N staging of cervical cancer.
  • OBJECTIVE: To evaluate the clinical impact of body diffusion weighted imaging (DWI) on the diagnosis and preoperative N staging of cervical cancer.
  • RESULTS: There were 5 adenocarcinomas and 19 epitheliomas showed with biopsy results, and DWI showed 21 cervical lesions out of them (87.5%).
  • ADC values of the normal cervix (n = 24), epithelioma (n = 19), and adenocarcinoma (n = 5) were (1.73 +/- 0.31) x 10(-3), (0.88 +/- 0.22) x 10(-3), and (1.08 +/- 0.12) x 10(-3) mm2/s, respectively.
  • CONCLUSIONS: ADC value in cervical carcinoma is lower than that in normal cervix, and ADC may have predictive value in subtype discrimination.


92. Hardiman KM, Cone M, Sheppard BC, Herzig DO: Disparities in the treatment of colon cancer in octogenarians. Am J Surg; 2009 May;197(5):624-8
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  • Advanced age is a principal risk factor for colorectal adenocarcinoma, but there are few data to guide treatment in the elderly patient population.
  • We compared demographics, stage at diagnosis, and initial treatment between patients younger than 80 years and those age 80 years or older.
  • Older patients were less likely to have colectomy for advanced or metastatic disease than younger patients.
  • Multivariate analysis revealed that predictors of receiving chemotherapy for patients >or=80 years of age include living in an urban county, younger age, and worse stage at diagnosis.
  • [MeSH-major] Adenocarcinoma / drug therapy. Adenocarcinoma / surgery. Colonic Neoplasms / drug therapy. Colonic Neoplasms / surgery. Healthcare Disparities. Practice Patterns, Physicians'

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  • (PMID = 19393356.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / UL1 RR024140
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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93. Landi MT, Zhao Y, Rotunno M, Koshiol J, Liu H, Bergen AW, Rubagotti M, Goldstein AM, Linnoila I, Marincola FM, Tucker MA, Bertazzi PA, Pesatori AC, Caporaso NE, McShane LM, Wang E: MicroRNA expression differentiates histology and predicts survival of lung cancer. Clin Cancer Res; 2010 Jan 15;16(2):430-41
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  • EXPERIMENTAL DESIGN: We analyzed miR expression in 165 adenocarcinoma and 125 squamous cell carcinoma (SQ) tissue samples from the Environment And Genetics in Lung cancer Etiology (EAGLE) study using a custom oligo array with 440 human mature antisense miRs.
  • RESULTS: MiR expression profiles strongly differed between adenocarcinoma and SQ (P(global) < 0.0001), particularly in the early stages, and included miRs located on chromosome loci most often altered in lung cancer (e.g., 3p21-22).
  • CONCLUSIONS: We identified a miR expression profile that strongly differentiated adenocarcinoma from SQ and had prognostic implications.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Lung Neoplasms / diagnosis. Lung Neoplasms / pathology. MicroRNAs / genetics
  • [MeSH-minor] Adult. Aged. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / mortality. Carcinoma, Squamous Cell / pathology. Case-Control Studies. Diagnosis, Differential. Female. Gene Expression Profiling. Gene Expression Regulation, Neoplastic / physiology. Humans. Male. Middle Aged. Neoplasm Staging / methods. Oligonucleotide Array Sequence Analysis. Prognosis. Smoking / epidemiology. Survival Analysis

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  • (PMID = 20068076.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / ZIA CP005803-16
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MicroRNAs
  • [Other-IDs] NLM/ NIHMS160630; NLM/ PMC3163170
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94. Yamakawa H, Ariga H, Enomoto A, Netsu S, Suzuki Y, Konno R: Meningeal dissemination from an ovarian carcinoma with effective response to intrathecal chemotherapy. Int J Clin Oncol; 2009 Oct;14(5):447-51
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  • Meningeal dissemination of the ovarian cancer was diagnosed, as adenocarcinoma cells were found by cerebrospinal fluid (CSF) cytology.
  • Establishing a diagnosis of carcinomatous meningitis may be difficult.
  • In this patient, CSF cytology was very effective in establishing the diagnosis, and the intrathecal administration of MTX and hydrocortisone was very effective.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Meningeal Carcinomatosis / drug therapy. Ovarian Neoplasms / pathology
  • [MeSH-minor] Electroencephalography. Female. Humans. Hydrocortisone / administration & dosage. Hydrocortisone / analogs & derivatives. Injections, Spinal. Magnetic Resonance Imaging. Methotrexate / administration & dosage. Middle Aged. Neoplasm Staging. Spinal Puncture. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19856055.001).
  • [ISSN] 1437-7772
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 3X7931PO74 / hydrocortisone acetate; WI4X0X7BPJ / Hydrocortisone; YL5FZ2Y5U1 / Methotrexate
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95. Costa Raiol LC, Figueira Silva EC, Mendes da Fonseca D, Leal MF, Guimarães AC, Calcagno DQ, Khayat AS, Assumpção PP, de Arruda Cardoso Smith M, Burbano RR: Interrelationship between MYC gene numerical aberrations and protein expression in individuals from northern Brazil with early gastric adenocarcinoma. Cancer Genet Cytogenet; 2008 Feb;181(1):31-5
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  • [Title] Interrelationship between MYC gene numerical aberrations and protein expression in individuals from northern Brazil with early gastric adenocarcinoma.
  • Early gastric cancer represents approximately 10% of gastric cancer cases in some services of Brazil, which underscores the need for early gastric cancer diagnosis that could lead to better prognosis.
  • To evaluate MYC copy number and its protein expression, we performed fluorescence in situ hybridization and immunohistochemical analyses in five early gastric adenocarcinomas in individuals from northern Brazil.
  • [MeSH-major] Adenocarcinoma / genetics. Chromosome Aberrations. Genes, myc. Stomach Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Brazil. Female. Gene Amplification. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Staging

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  • (PMID = 18262050.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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96. Righi V, Mucci A, Schenetti L, Bacci A, Agati R, Leonardi M, Schiavina R, Martorana G, Liguori G, Calabrese C, Boschetti E, Bonora S, Tugnoli V: Identification of mobile lipids in human cancer tissues by ex vivo diffusion edited HR-MAS MRS. Oncol Rep; 2009 Dec;22(6):1493-6
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  • Magnetic Resonance Spectroscopy visible mobile lipids are considered important markers in the diagnosis of human cancer and are thought to be closely involved in various aspects of tumour transformation, such as cell proliferation, necrosis, apoptosis, hypoxia and drug resistance.
  • A method allowing the straightforward identification of the lipid classes contributing to the mobile lipids in human malignant tissues is highly advisable.
  • Ex vivo High Resolution Magic Angle Spinning Magnetic Resonance Spectroscopy was done directly on human cerebral, renal and colorectal malignant tissue specimens.
  • Cholesterol, triglycerides and phosphatidylcholine are simultaneously detected and all contribute to the mobile lipid resonances present in malignant glioma and clear cell renal carcinoma tissue specimens spectra.
  • On the contrary, papillary cell renal carcinoma spectrum is predominated by phosphatidylcholine resonances and that of colorectal adenocarcinoma is characterized by signals arising from triglycerides.

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  • (PMID = 19885604.001).
  • [ISSN] 1791-2431
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Lipids; 0 / Triglycerides
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97. Schmidt N, Peitz U, Lippert H, Malfertheiner P: Missing gastric cancer in dyspepsia. Aliment Pharmacol Ther; 2005 Apr 1;21(7):813-20
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  • METHODS: In 215 patients at initial diagnosis of gastric adenocarcinoma, symptoms were classified as alarm and non-alarm.
  • [MeSH-major] Diagnostic Errors. Dyspepsia / etiology. Gastroscopy / standards. Stomach Neoplasms / diagnosis

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  • (PMID = 15801916.001).
  • [ISSN] 0269-2813
  • [Journal-full-title] Alimentary pharmacology & therapeutics
  • [ISO-abbreviation] Aliment. Pharmacol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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98. Dejmek A, Hjerpe A: The combination of CEA, EMA, and BerEp4 and hyaluronan analysis specifically identifies 79% of all histologically verified mesotheliomas causing an effusion. Diagn Cytopathol; 2005 Mar;32(3):160-6
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  • A previously tested antibody panel identified three criteria of major importance for distinguishing between mesothelioma and adenocarcinoma (ACA): carcinoembryonic antigen (CEA), BerEp4, and epithelial membrane antigen (EMA) accentuated at the cell membrane.
  • [MeSH-major] Adenocarcinoma / pathology. Biomarkers, Tumor / metabolism. Mesothelioma / diagnosis. Pleural Effusion, Malignant / pathology. Pleural Neoplasms / diagnosis
  • [MeSH-minor] Carcinoembryonic Antigen / metabolism. Diagnosis, Differential. Humans. Hyaluronic Acid / metabolism. Immunohistochemistry. Mucin-1 / metabolism. Vimentin / metabolism

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 15690331.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Mucin-1; 0 / Vimentin; 0 / human epithelial antigen-125; 9004-61-9 / Hyaluronic Acid
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99. Nikou GC, Marinou K, Thomakos P, Papageorgiou D, Sanzanidis V, Nikolaou P, Kosmidis C, Moulakakis A, Mallas E: Chromogranin a levels in diagnosis, treatment and follow-up of 42 patients with non-functioning pancreatic endocrine tumours. Pancreatology; 2008;8(4-5):510-9
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  • [Title] Chromogranin a levels in diagnosis, treatment and follow-up of 42 patients with non-functioning pancreatic endocrine tumours.
  • They are characterized by the absence of symptoms of hormone hypersecretion and frequently have clinical manifestations similar to the more common exocrine pancreatic adenocarcinoma.
  • METHODS: Twenty-five males and 17 females were included, and the mean age at diagnosis was 52.3 years (range: 26-68 years).
  • The diagnosis for each patient was established by histopathological examination and immunohistochemistry.
  • After the histopathological confirmation of diagnosis and during the follow-up period, patients were evaluated clinically and radiologically (including OctreoScan), whilst fasting gut hormones (including CgA) were also estimated.
  • At diagnosis, all patients were checked for the presence of multiple endocrine neoplasia type I syndrome.
  • RESULTS: Dyspepsia (66.5%) and weight loss (47.6%) were the most common symptoms at diagnosis, while in 21.4% of patients tumour lesions were revealed incidentally.
  • Plasma CgA levels were significantly or moderately elevated in all patients with liver metastases at diagnosis (64.3%).
  • (3) surgeryin patients with localized disease at presentation can be curative, while it can also reduce tumour burden in patients with metastases;.
  • (4) long-acting somatostatin analogues provide good quality of life and temporary disease stabilization in patients with low-grade tumours;.
  • [MeSH-major] Biomarkers, Tumor / blood. Chemoembolization, Therapeutic. Chromogranin A / blood. Multiple Endocrine Neoplasia Type 1 / blood. Neuroendocrine Tumors / blood. Pancreatic Neoplasms / blood
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging

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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18765956.001).
  • [ISSN] 1424-3911
  • [Journal-full-title] Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
  • [ISO-abbreviation] Pancreatology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromogranin A
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100. Fukunaga M, Takahashi H, Yasuda M: Mesonephric adenocarcinoma of the uterine cervix: a case report with immunohistochemical and ultrastructural studies. Pathol Res Pract; 2008;204(9):671-6
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  • [Title] Mesonephric adenocarcinoma of the uterine cervix: a case report with immunohistochemical and ultrastructural studies.
  • A very rare case of mesonephric adenocarcinoma with lobular mesonephric hyperplasia in the uterine cervix of a 46-year-old female is presented.
  • The patient was alive without disease at 4 months after surgery.
  • [MeSH-major] Adenocarcinoma / ultrastructure. Mesonephroma / ultrastructure. Uterine Cervical Neoplasms / ultrastructure
  • [MeSH-minor] Carcinoma, Endometrioid / pathology. Diagnosis, Differential. Female. Humans. Hysterectomy. Immunohistochemistry. Microscopy, Electron, Transmission. Middle Aged






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