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1. Bernstein M, Khu KJ: Is there too much variability in technical neurosurgery decision-making? Virtual Tumour Board of a challenging case. Acta Neurochir (Wien); 2009 Apr;151(4):411-2; discussion 412-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is there too much variability in technical neurosurgery decision-making? Virtual Tumour Board of a challenging case.
  • Decades into the era of evidence-based medicine, most neurosurgeons are aware that the vast majority of our day-to-day patient care decisions are not guided by class I evidence, especially those related to surgical procedures.
  • A 35-year-old man presented with a 6-month history of visual loss, cognitive decline and endocrine dysfunction.
  • The pathology was adamantinomatous craniopharyngioma.
  • [MeSH-major] Craniopharyngioma / surgery. Craniotomy / methods. Evidence-Based Medicine / standards. Neurosurgical Procedures / methods. Pituitary Neoplasms / surgery. Referral and Consultation / standards

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
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  • (PMID = 19255714.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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2. Saeger W: [Pituitary gland tumors]. Pathologe; 2003 Jul;24(4):255-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This sub-classification is not necessary in every case, but must be performed if unusual findings are observed during surgery or if surgery is unsuccessful and radiation or drug-therapy is planned.
  • We differentiated monohormonal densely or sparsely granulated GH-cell adenomas, monohormonal sparsely or very rarely densely granulated prolactin cell adenomas, monohormonal densely or sparsely ACTH-cell adenomas, monohormonal TSH-cell adenomas and FSH/LH cell adenomas from bihormonal adenomas of mammosomatotroph or GH/prolactin cell type or of the acidophil stem cell adenoma type.
  • These appear as subtypes of one entity deriving from the gonadotroph cell type.
  • Craniopharyngiomas are classified into adamantinous and papillary types, which are not only structurally but also clinically different.
  • If adamantinous craniopharyngiomas show very strongly regressive changes, immunostaining for keratin may be necessary to identify the squamous epithelia for the demonstration of craniopharyngioma.

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  • (PMID = 14513271.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Pituitary Hormones
  • [Number-of-references] 27
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3. Vidal S, Scheithauer BW, Kovacs K, Lloyd RV: Angiogenesis and the growth potential of craniopharyngiomas. Endocr Pathol; 2005;16(3):219-28
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiogenesis and the growth potential of craniopharyngiomas.
  • The present study was performed to evaluate the role of neovascularization on the behavior of craniopharyngiomas as well as the contribution of endothelial cell proliferation and migration in the remodeling and expansion of the vascular network associated with angiogenesis.
  • Fourteen primary tumors were studied, all of the adamantinomatous type.
  • Immunohistochemistry demonstrated that integrin alphavbeta3 expression was restricted to tumor vasculature; the tumor cells were immunonegative.
  • More studies are needed to assess whether integrin alphavbeta3 antagonists or drugs that arrest the cell cycle of endothelial cells can inhibit angiogenesis in craniopharyngiomas.
  • [MeSH-major] Craniopharyngioma / blood supply. Neovascularization, Pathologic / pathology. Pituitary Neoplasms / blood supply
  • [MeSH-minor] Adolescent. Antigens, CD34 / metabolism. Biomarkers, Tumor / metabolism. Cell Count. Child. Child, Preschool. Female. Humans. Immunoenzyme Techniques. Integrin alphaVbeta3 / metabolism. Ki-67 Antigen / metabolism. Male. Microcirculation. Retrospective Studies

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  • (PMID = 16299405.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Integrin alphaVbeta3; 0 / Ki-67 Antigen
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