[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 78569
1. Purtscher K: [Trauma in childhood--risks for the child's development]. Psychiatr Danub; 2008 Dec;20(4):513-20
MedlinePlus Health Information. consumer health - Post-Traumatic Stress Disorder.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Trauma in childhood--risks for the child's development].
  • [Transliterated title] Traumatisierung in der Kindheit--Folgen für die Entwicklung.
  • Studies of early childhood traumatic experiences have clearly established a causal relationship between the experience of childhood psychic trauma and long-term effects on cognitive emotional und social development.
  • More intermediate-term consequences of childhood trauma are likely to reside in higher rates of risk for the development of conduct disorders, higher rates of teenage pregnancy, school droop out, and involvement with the juvenile court jurisdiction because of law violations.
  • To meet a child needs in daily life after traumatic experience different times of support and therapy are needed and involves parents, teachers, social workers and therapists as well.
  • [MeSH-minor] Adolescent. Child. Conduct Disorder / diagnosis. Conduct Disorder / psychology. Conduct Disorder / therapy. Emotions. Female. Humans. Internal-External Control. Juvenile Delinquency / prevention & control. Juvenile Delinquency / psychology. Male. Patient Care Team. Pregnancy. Pregnancy in Adolescence / prevention & control. Pregnancy in Adolescence / psychology. Risk Factors

  • MedlinePlus Health Information. consumer health - Child Mental Health.
  • MedlinePlus Health Information. consumer health - Mental Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19011593.001).
  • [ISSN] 0353-5053
  • [Journal-full-title] Psychiatria Danubina
  • [ISO-abbreviation] Psychiatr Danub
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Croatia
  •  go-up   go-down


2. Grassi-Oliveira R, Stein LM, Pezzi JC: [Translation and content validation of the Childhood Trauma Questionnaire into Portuguese language]. Rev Saude Publica; 2006 Apr;40(2):249-55

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Translation and content validation of the Childhood Trauma Questionnaire into Portuguese language].
  • [Transliterated title] Tradução e validação de conteúdo da versão em português do Childhood Trauma Questionnaire.
  • OBJECTIVE: The Childhood Trauma Questionnaire is a self-applied instrument for adolescents and adults to assess childhood abuse.
  • [MeSH-major] Child Abuse / diagnosis. Surveys and Questionnaires

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16583035.001).
  • [ISSN] 0034-8910
  • [Journal-full-title] Revista de saúde pública
  • [ISO-abbreviation] Rev Saude Publica
  • [Language] por
  • [Publication-type] English Abstract; Journal Article; Validation Studies
  • [Publication-country] Brazil
  •  go-up   go-down


3. Tomás Vila M, Miralles Torres A, Beseler Soto B: [Spanish version of the Pediatric Sleep Questionnaire (PSQ). A useful instrument in investigation of sleep disturbances in childhood. Reliability analysis]. An Pediatr (Barc); 2007 Feb;66(2):121-8
MedlinePlus Health Information. consumer health - Sleep Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Spanish version of the Pediatric Sleep Questionnaire (PSQ). A useful instrument in investigation of sleep disturbances in childhood. Reliability analysis].
  • [Transliterated title] Versión española del Pediatric Sleep Questionnaire. Un instrumento útil en la investigación de los trastornos del sueño en la infancia. Análisis de su fiabilidad.
  • The Pediatric Sleep Questionnaire (PSQ) has two versions: a shorter one, which has been validated for sleep-related breathing disorders, and an extended version, which deals with a wider range of sleep disturbances.
  • [MeSH-minor] Child. Humans. Language. Reproducibility of Results

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17306097.001).
  • [ISSN] 1695-4033
  • [Journal-full-title] Anales de pediatría (Barcelona, Spain : 2003)
  • [ISO-abbreviation] An Pediatr (Barc)
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Validation Studies
  • [Publication-country] Spain
  •  go-up   go-down


Advertisement
4. Nitzko S: [Overweight and obesity in childhood and adolescence]. Prax Kinderpsychol Kinderpsychiatr; 2010;59(10):831-51
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Overweight and obesity in childhood and adolescence].
  • [Transliterated title] Ubergewicht und Adipositas in Kindheit und Jugend.
  • Firstly, essential developmental aspects of the focused periods of life, namely childhood and adolescence, are discussed.
  • Furthermore, different issues of overweight and obesity in childhood and adolescence are highlighted.
  • Finally, the focus is on the therapy of obesity in childhood and adolescence.
  • [MeSH-minor] Adolescent. Causality. Child. Combined Modality Therapy. Comorbidity. Cooperative Behavior. Cross-Sectional Studies. Female. Germany. Humans. Interdisciplinary Communication. Male. Mental Disorders / epidemiology. Mental Disorders / psychology. Self Concept

  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Obesity in Children.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21290853.001).
  • [ISSN] 0032-7034
  • [Journal-full-title] Praxis der Kinderpsychologie und Kinderpsychiatrie
  • [ISO-abbreviation] Prax Kinderpsychol Kinderpsychiatr
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  •  go-up   go-down


5. La Scala CS, Naspitz CK, Solé D: [Adaptation and validation of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) in Brazilian asthmatic children and adolescents]. J Pediatr (Rio J); 2005 Jan-Feb;81(1):54-60
MedlinePlus Health Information. consumer health - Asthma in Children.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adaptation and validation of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) in Brazilian asthmatic children and adolescents].
  • [Transliterated title] Adaptação e validação do Pediatric Asthma Quality of Life Questionnaire (PAQLQ-A) em crianças e adolescentes brasileiros com asma.
  • OBJECTIVES: To translate the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) into Portuguese and adapt it to the Brazilian context, for use in children and adolescents with asthma and to validate the adapted version of the questionnaire (PAQLQ-A).
  • [MeSH-minor] Adolescent. Brazil. Child. Female. Humans. Male. Reproducibility of Results. Severity of Illness Index. Translating

  • Genetic Alliance. consumer health - Asthma.
  • MedlinePlus Health Information. consumer health - Asthma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Pediatr (Rio J). 2005 May-Jun;81(3):268-9; author reply 269-70 [15951917.001]
  • (PMID = 15742087.001).
  • [ISSN] 0021-7557
  • [Journal-full-title] Jornal de pediatria
  • [ISO-abbreviation] J Pediatr (Rio J)
  • [Language] por
  • [Publication-type] English Abstract; Journal Article; Validation Studies
  • [Publication-country] Brazil
  •  go-up   go-down


6. Walter U, Kramer S, Röbl M: [Physical (in)activity in childhood and adolescence]. Dtsch Med Wochenschr; 2005 Dec 16;130(50):2876-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Physical (in)activity in childhood and adolescence].
  • [Transliterated title] Körperliche (In)Aktivität in Kindheit und Jugend.
  • Physical inactivity in childhood and youth is related with coronary heart disease risk factors and higher prevalence of obesity.
  • [MeSH-minor] Adolescent. Body Mass Index. Child. Child, Preschool. Germany. Health Services Needs and Demand / trends. Humans. Motor Skills. Physical Education and Training / trends. Physical Endurance. Physical Fitness


7. Tesch FC, Oliveira BH, Leão A: [Semantic equivalence of the Brazilian version of the Early Childhood Oral Health Impact Scale]. Cad Saude Publica; 2008 Aug;24(8):1897-909
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Semantic equivalence of the Brazilian version of the Early Childhood Oral Health Impact Scale].
  • [Transliterated title] Equivalência semântica da versão em português do instrumento Early Childhood Oral Health Impact Scale.
  • The North American instrument Early Childhood Oral Health Impact Scale (ECOHIS) was created to assess the oral health-related quality of life of preschool children and their families.
  • [MeSH-minor] Brazil. Child. Child, Preschool. Cross-Cultural Comparison. Cultural Characteristics. Humans

  • Genetic Alliance. consumer health - Oral Health.
  • MedlinePlus Health Information. consumer health - Dental Health.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18709230.001).
  • [ISSN] 1678-4464
  • [Journal-full-title] Cadernos de saúde pública
  • [ISO-abbreviation] Cad Saude Publica
  • [Language] por
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Brazil
  •  go-up   go-down


8. Neumann E, Tress W: [Close relationships in childhood and adulthood from the viewpoint of structural analysis of social behavior (SASB) and attachment theory]. Psychother Psychosom Med Psychol; 2007 Mar-Apr;57(3-4):145-53
MedlinePlus Health Information. consumer health - Family Issues.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Close relationships in childhood and adulthood from the viewpoint of structural analysis of social behavior (SASB) and attachment theory].
  • [Transliterated title] Enge Beziehungen in Kindheit und Erwachsenenalter aus der Sicht der Strukturalen Analyse Sozialen Verhaltens (SASB) und der Bindungstheorie.
  • The focus is on the most important relationships during life-span: relationships with mother and father in childhood, which were measured retrospectively, and romantic relationships in adulthood.
  • [MeSH-minor] Adult. Anxiety / psychology. Child. Family Relations. Humans. Personal Autonomy. Psychophysiologic Disorders / psychology. Retrospective Studies. Surveys and Questionnaires

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17211774.001).
  • [ISSN] 0937-2032
  • [Journal-full-title] Psychotherapie, Psychosomatik, medizinische Psychologie
  • [ISO-abbreviation] Psychother Psychosom Med Psychol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


9. Voll R: [A rare differential diagnosis of a somatoform autonomous disorder of the gastro-intestinal tract: the hepatocellular liver carcinoma in childhood]. Z Kinder Jugendpsychiatr Psychother; 2008 Jul;36(4):275-8
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A rare differential diagnosis of a somatoform autonomous disorder of the gastro-intestinal tract: the hepatocellular liver carcinoma in childhood].
  • [Transliterated title] Eine seltene Differenzialdiagnose somatoformer autonomer Funktionsstörung des Abdominaltraktes: das hepatozelluläre Leberkarzinom in der Kindheit.
  • OBJECTIVES: A severely ill 11-year-old boy came to the child psychiatric outpatient department of the Fachkrankenhaus Neckargemünd with the diagnosis of a somatoform disorder.
  • CONCLUSIONS: The symptoms of the hepatocellular carcinoma, which rarely occurs in childhood, can perfectly mimic those of a somatoform disorder of the gastro-intestinal tract.
  • [MeSH-minor] Child. Child Reactive Disorders / diagnosis. Child Reactive Disorders / psychology. Child Reactive Disorders / therapy. Combined Modality Therapy. Diagnosis, Differential. Family Therapy. Follow-Up Studies. Hepatectomy / psychology. Humans. Male. Neuropsychological Tests. Psychotherapy. Referral and Consultation. Sick Role

  • Genetic Alliance. consumer health - Hepatocellular carcinoma, childhood.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18654959.001).
  • [ISSN] 1422-4917
  • [Journal-full-title] Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie
  • [ISO-abbreviation] Z Kinder Jugendpsychiatr Psychother
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


10. Brainin E, Teicher S: [The terror from the outside--child survivors of the Spiegelgrund traumatic experiences in childhood and their effects]. Prax Kinderpsychol Kinderpsychiatr; 2009;58(7):530-52
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The terror from the outside--child survivors of the Spiegelgrund traumatic experiences in childhood and their effects].
  • [Transliterated title] Terror von aussen am Beispiel Spiegelgrund Traumatische Erfahrungen in der Kindheit und deren Folgen.
  • The overcoming and dealing with the terrible past during childhood were discussed as well as the reactions to the interviews of the members of the study group.
  • The theoretical frame was Anna Freud's work on child survivors of the Theresienstadt concentration camp: "An Experiment in Group Upbringing": Different factors for the survival and the working through afterwards are discussed as well as the different psychoanalytical trauma concepts.
  • The former experiences of the children in institutions of the social administration in Austria differ from the experiences of Jewish child survivors.
  • [MeSH-minor] Adolescent. Austria. Child. Germany. History, 20th Century. Humans

  • MedlinePlus Health Information. consumer health - Post-Traumatic Stress Disorder.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19911766.001).
  • [ISSN] 0032-7034
  • [Journal-full-title] Praxis der Kinderpsychologie und Kinderpsychiatrie
  • [ISO-abbreviation] Prax Kinderpsychol Kinderpsychiatr
  • [Language] ger
  • [Publication-type] English Abstract; Historical Article; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


11. Schmidt-Bacher AE, Kahlert C, Kolling G: [Accuracy of two autorefractors--Pediatric Autorefractor plusoptiX and Retinomax--in cycloplegic children in comparison to retinoscopy]. Klin Monbl Augenheilkd; 2010 Oct;227(10):792-7
MedlinePlus Health Information. consumer health - Amblyopia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Accuracy of two autorefractors--Pediatric Autorefractor plusoptiX and Retinomax--in cycloplegic children in comparison to retinoscopy].
  • [Transliterated title] Zur Messung der objektiven Refraktion in Zykloplegie im Kindesalter mit Skiaskopie und automatischer Refraktometrie mit dem Pediatric Autorefractor und dem Retinomax.
  • In a prospective study we compared readings from two hand-held photorefractors, the Pediatric Autorefractor and the Retinomax, to those from retinoscopy.
  • All patients underwent standardised cycloplegia measurements first by the Pediatric Autorefractor plusoptiX A 08 in 1 metre working distance, then adding an infrared filter to reduce interferences, followed by the Retinomax K-plus 3 in 5 cm working distance and retinoscopy as reference on the right eye.
  • RESULTS: Spherical equivalents measured by the Pediatric Autorefractor plusoptiX A 08 coincided in 51.2% with retinoscopy (± 0.5 D).
  • The Pediatric Autorefractor is not suited for everyday clinical routine due to a low success rate of 50% and tight measuring range of + 5.0 to -7.0 D in spherical equivalents.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Equipment Design. Female. Humans. Infant. Male. Ophthalmic Solutions. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • [CommentIn] Klin Monbl Augenheilkd. 2012 Oct;229(10):1045; author reply 1046 [23096147.001]
  • (PMID = 20963682.001).
  • [ISSN] 1439-3999
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Mydriatics; 0 / Ophthalmic Solutions; I76F4SHP7J / Cyclopentolate
  •  go-up   go-down


12. Lampert T: [Setting the course early: relevance of childhood and adolescence for health in later life]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz; 2010 May;53(5):486-97
MedlinePlus Health Information. consumer health - Toddler Development.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Setting the course early: relevance of childhood and adolescence for health in later life].
  • [Transliterated title] Frühe Weichenstellung: Zur Bedeutung der Kindheit und Jugend für die Gesundheit im späteren Leben.
  • The article examines the importance of childhood and adolescence for health in later life against the background of the population-aging process and the debate on the social challenges expected to result from this process.
  • [MeSH-major] Adolescent Development. Child Development. Chronic Disease / epidemiology. Disabled Persons / statistics & numerical data. Population Dynamics
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Forecasting. Germany. Health Promotion / trends. Health Services Needs and Demand / trends. Humans. Infant. Infant, Newborn. Middle Aged. Pregnancy. Primary Prevention / trends. Risk Factors. Young Adult


13. Hardt J, Hoffmann SO: [Childhood in flux--Part I: Ancient world until modern times]. Prax Kinderpsychol Kinderpsychiatr; 2006;55(4):271-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Childhood in flux--Part I: Ancient world until modern times].
  • [Transliterated title] Kindheit im Wandel--Teil I: Antike bis zur Neuzeit.
  • Scientific research on childhood constitutes a relatively new field.
  • Until medieval times, a child's life did not count for much, that is, as long as the child was not the beneficiary of an inheritance.
  • Despite Rousseau's idealistic concept of education as a kind of identification process for the child, he put his own five children into the foundling hospital of Paris; he was bothered by them when writing.
  • Up to the beginning of the 19th century, the value of a child was determined by his or her ability to work.
  • [MeSH-major] Child Abuse / history. Child Care / history. Child, Abandoned / history. Employment / history. Infanticide / history. Social Values
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Europe. Female. History, 15th Century. History, 16th Century. History, 17th Century. History, 18th Century. History, 19th Century. History, Ancient. History, Medieval. Humans. Infant. Male. United States

  • MedlinePlus Health Information. consumer health - Child Abuse.
  • MedlinePlus Health Information. consumer health - Child Care.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17436560.001).
  • [ISSN] 0032-7034
  • [Journal-full-title] Praxis der Kinderpsychologie und Kinderpsychiatrie
  • [ISO-abbreviation] Prax Kinderpsychol Kinderpsychiatr
  • [Language] ger
  • [Publication-type] English Abstract; Historical Article; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


14. Wingenfeld K, Spitzer C, Mensebach C, Grabe HJ, Hill A, Gast U, Schlosser N, Höpp H, Beblo T, Driessen M: [The German version of the Childhood Trauma Questionnaire (CTQ): preliminary psychometric properties]. Psychother Psychosom Med Psychol; 2010 Nov;60(11):442-50
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The German version of the Childhood Trauma Questionnaire (CTQ): preliminary psychometric properties].
  • [Transliterated title] Die deutsche Version des Childhood Trauma Questionnaire (CTQ): Erste Befunde zu den psychometrischen Kennwerten.
  • Given the relevance of child maltreatment for the development and treatment of many mental disorders, the objective of our study was the psychometric evaluation of the German version of the Childhood Trauma Questionnaire (CTQ).
  • The psychometric properties of the German version of the CTQ were similar to the American original; it proved to be a reliable and valid screen for the retrospective assessment of child maltreatment.
  • [MeSH-major] Adult Survivors of Child Abuse / psychology. Child Abuse / psychology. Child Abuse, Sexual / psychology
  • [MeSH-minor] Adult. Checklist. Child. Dissociative Disorders / psychology. Factor Analysis, Statistical. Female. Germany. Humans. Language. Male. Psychometrics. Reproducibility of Results. Stress Disorders, Post-Traumatic / psychology. Surveys and Questionnaires

  • MedlinePlus Health Information. consumer health - Child Abuse.
  • MedlinePlus Health Information. consumer health - Child Sexual Abuse.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 20200804.001).
  • [ISSN] 0937-2032
  • [Journal-full-title] Psychotherapie, Psychosomatik, medizinische Psychologie
  • [ISO-abbreviation] Psychother Psychosom Med Psychol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Validation Studies
  • [Publication-country] Germany
  •  go-up   go-down


15. Fauzdar A, Mahajan A, Jain D, Mishra M, Raina V: Amplification of RUNX1 gene in two new cases of childhood B-cell precursor acute lymphoblastic leukemia: A case report. J Clin Oncol; 2009 May 20;27(15_suppl):e21000

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amplification of RUNX1 gene in two new cases of childhood B-cell precursor acute lymphoblastic leukemia: A case report.
  • : e21000 Background: Chromosome abnormalities of leukemia cells have important prognostic significance in childhood acute lymphoblastic leukemia (ALL).
  • B-cell precursor acute lymphoblastic leukemia (BCP-ALL) ETV6/RUNX1 (alias TEL/AML1) is most frequent i.e.
  • Bone marrow karyotype in combination with molecular cytogenetic techniques like FISH should be done for improvement in sensitivity and accurate cytogenetic analysis in childhood ALL patients for proper identification of prognostic group for optimum treatment.
  • This is one of the few reported studies worldwide for amplification of RUNX1 gene from Indian subcontinent in childhood BCP-ALL.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27960689.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


16. Khattab TM, Jastaniah WA, Felimban SK, Elemam N, Abdullah K, Ahmed B: How could improvement in the management of T-cell acute lymphoblastic leukemia be achieved? Experience of Princess Nourah Oncology Center, National Guard Hospital, Jeddah, Saudi Arabia. J Clin Oncol; 2009 May 20;27(15_suppl):10048

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] How could improvement in the management of T-cell acute lymphoblastic leukemia be achieved? Experience of Princess Nourah Oncology Center, National Guard Hospital, Jeddah, Saudi Arabia.
  • : 10048 Background: T-cell acute lymphoblastic leukemia (T-ALL) is representing 10-15% of pediatric ALL.
  • Our published data showed that T-ALL phenotype patients fared poorly with 5 year survival of 27% versus 83% for precursor B-ALL (Recent Advances Research Update: 2006, 7; 1, P 51-56).
  • OBJECTIVES: We reviewed all patients diagnosed with T-ALL to assess risk classification according to NCI criteria, type of therapy received, overall survival and causes of mortality.
  • METHODS: Retrospective review of all patients files diagnosed with T-ALL from 1989 until now with data collection including; sex, age, white cell count (WBCs), CNS disease, type of protocol used, length of survival, overall survival, cause of death (toxic, disease).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962474.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


17. Queudeville M, Eckhoff SM, Debatin K, Meyer LH: Correlatoin of apoptosis signaling in primary pediatric BCP-ALL xenograft cells with the kinetics of engraftment in vivo in a NOD/SCID model and patient outcome. J Clin Oncol; 2009 May 20;27(15_suppl):10043

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correlatoin of apoptosis signaling in primary pediatric BCP-ALL xenograft cells with the kinetics of engraftment in vivo in a NOD/SCID model and patient outcome.
  • : 10043 Background: We previously identified the importance of intact apoptosis signaling for treatment response in pediatric ALL and AML by analyzing two key apoptogenic events, caspase-3 activation and cytochrome c release.
  • Using a NOD/SCID mouse model for pediatric BCP-ALL we found that short time from transplant to overt leukemia in the recipient mice (short time to leukemia, TTLshort) determines poor patient outcome.
  • METHODS: In this study we investigated the importance of deficient apoptosis signaling for leukemia engraftment in this model.
  • CONCLUSIONS: Our finding in the NOD/SCID/huALL model matches our results in pediatric ALL and AML to conclude that the functional integrity of a downstream apoptotic checkpoint is an important feature regulating leukemia biology.
  • Thus, deficient apoptosis signaling appears to determine rapid engraftment of leukemia cells in the NOD/SCID model in vivo and consequently poor patient outcome.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962469.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


18. Abdalla DM, Hamza MA, Kandil AE, Younes LK, Sorrour AF: MYCN gene amplification and DNA ploidy in peripheral neuroblastic tumors. J Clin Oncol; 2009 May 20;27(15_suppl):e22123

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e22123 Background: Neuroblastoma is a neuroblastic tumor of the primordial crest cells which are precursors of the sympathetic nervous system and is the most common extracranial solid tumor of childhood comprising between 8 and 10% of all childhood cancers.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27963561.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


19. Meyer LH, Zangrando A, Eckhoff SM, Queudeville M, Vendramini E, Basso G, Te Kronnie G, Debatin K: Association of time to leukemia (TTL) in NOD/SCID mice with expression of apoptosis regulators in pediatric ALL. J Clin Oncol; 2009 May 20;27(15_suppl):10042

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of time to leukemia (TTL) in NOD/SCID mice with expression of apoptosis regulators in pediatric ALL.
  • : 10042 Background: Acute lymphoblastic leukemia (ALL) is the most frequent malignant disease in childhood.
  • In a recent study we transplanted pediatric leukemia samples from newly diagnosed BCP-ALL patients into NOD/SCID mice.
  • Time to leukemia (TTL) was analyzed for each patient sample as time from transplant to overt leukemia in the recipients.
  • Patients whose leukemia cells engrafted rapidly showed a clearly inferior relapse free survival in contrast to patient samples with prolonged in vivo growth.
  • METHODS: Gene expression profiles of ALL samples (N = 14) with short versus long TTL in the xenograft model were analyzed using a human whole genome array (Affymetrix U133 Plus 2.0) correlating gene expression values (relative expression) to the time from transplant to manifestation of leukemia in the NOD/SCID mice (TTL, in weeks) by quantitative traits analysis (QTA).
  • Patient samples exhibiting a short time to overt leukemia in the xenotransplant model associated with poor relapse free survival showed down-regulated XAF1 and impaired caspase-3 activation leading to decreased apoptosis of the leukemia cells.
  • CONCLUSIONS: Taken together, we used a novel approach directly correlating gene expression values to time from transplant to overt leukemia (TTL) identifying the apoptosis regulator XAF1 to be associated with poor outcome of patients.
  • Small XIAP-inhibiting molecules can be used to substitute the lacking inhibitory effect of down-regulated XAF1 in these poor responding pediatric ALL patients.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962468.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


20. Gumy-Pause F, Ozsahin H, Khoshbeen-Boudal M, Pardo B, Betts D, Maillet P, Sappino A: ATM gene analysis in neuroblastoma: A report from the COG. J Clin Oncol; 2009 May 20;27(15_suppl):10058

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 10058 Background: Neuroblastoma (NB) is the most common malignant disease of infancy and accounts for approximately 8% of all childhood cancers.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962454.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


21. Evans WE, Relling MV: Pharmacogenomics of childhood acute lymphoblastic leukemia (ALL). J Clin Oncol; 2009 May 20;27(15_suppl):s3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacogenomics of childhood acute lymphoblastic leukemia (ALL).
  • : s3 Childhood ALL is a model for drug-responsive cancer: it is successfully cured with medications in 85%-90% of patients, but relapse remains unacceptably high for some subgroups, and therapy is complicated by the occurrence of adverse effects.
  • Based on these studies, candidate gene genotyping has been already incorporated into the treatment of childhood ALL and integrated with electronic medical records at St. Jude to optimize use of a few medications.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962369.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


22. Smith MA, Morton CL, Carol H, Gorlick RG, Kang MH, Keir ST, Kolb EA, Lock RB, Maris JM, Houghton PJ: Pediatric Preclinical Testing Program (PPTP) testing of the CENP-E inhibitor GSK923295A. J Clin Oncol; 2009 May 20;27(15_suppl):10015

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric Preclinical Testing Program (PPTP) testing of the CENP-E inhibitor GSK923295A.
  • METHODS: The PPTP includes a molecularly characterized in vitro panel of cell lines (n = 27) and in vivo panel of xenografts (n = 60) representing most of the common types of childhood solid tumors and childhood acute lymphoblastic leukemia (ALL).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962529.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


23. Mukhopadhyay A, Gupta P, Mukhopadhyay S, Dey S, Basak J, Pandey R: Result of adolescent acute lymphoblastic leukemia protocol (MCP 841) from a developing country. J Clin Oncol; 2009 May 20;27(15_suppl):10046

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Result of adolescent acute lymphoblastic leukemia protocol (MCP 841) from a developing country.
  • : 10046 Background: Acute Lymphatic Leukemia is a curable disease in the range of 80 - 90% in developed countries by aggressive protocol like BFM, St. Judes' but result is much less in adolescence age group (60-70%).
  • As compared to our all pediatric ALL group the outcome is much less and complications are much more.
  • CONCLUSIONS: The data of acute lymphatic leukemia in adolescent is not satisfactory as compared to other pediatric patients.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962472.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


24. Morris B, Khan R, Ledet D, Howell C, Pui C, Hudson M, Ness K: Neurological morbidity in survivors of childhood acute lymphoblastic leukemia (ALL). J Clin Oncol; 2009 May 20;27(15_suppl):9529

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurological morbidity in survivors of childhood acute lymphoblastic leukemia (ALL).
  • Because treatment-related neurological morbidity is recognized but poorly characterized, the objective of this cross-sectional study was to estimate the prevalence of neurological symptoms and signs in long-term survivors of childhood ALL.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27964517.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


25. Eichstadt SL, Dahl GV, Fisher PG, Ford JM, Schiffman JD: Correlation of a family history of cancer with risk of relapse and death in pediatric cancer patients. J Clin Oncol; 2009 May 20;27(15_suppl):10029

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correlation of a family history of cancer with risk of relapse and death in pediatric cancer patients.
  • Such information would be valuable for prognosis, refining treatment protocols, and long-term follow-up in pediatric patients with FHC.
  • METHODS: An historical cohort study of all pediatric patients diagnosed with cancer at Lucile Packard Children's Hospital at Stanford from 1999 - 2002 was performed (n = 363, mean age: 8.4 yrs [0-28 yrs]).
  • RESULTS: 108 (41%) newly diagnosed pediatric patients had reported FHC (1st Degree: n = 14 [5%], 2nd Degree: n = 58 [22%], 3rd Degree: n = 36 [14%]).
  • For patients diagnosed with any pediatric cancer and positive FHC in 1st degree relative, RR of death was significantly elevated (3.74, 95% CI 1.20-11.70).
  • CONCLUSIONS: Pediatric cancer patients with positive FHC among 1st and/or 2nd degree relatives appear to have higher relative risk of relapse compared to those with negative FHC.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962589.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


26. Te Loo DM, van Schie RM, Hoogerbrugge PM: Effect of azole antifungal therapy on vincristine toxicity in childhood acute lymphoblastic leukemia. J Clin Oncol; 2009 May 20;27(15_suppl):10049

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of azole antifungal therapy on vincristine toxicity in childhood acute lymphoblastic leukemia.
  • : 10049 Background: Vincristine is one of the corner stitches in the treatment of children with acute lymphoblastic leukemia (ALL).
  • METHODS: In total, twenty pediatric patients with de novo ALL were included in this study.
  • Three patients (15%) treated with azole therapy developed severe toxicity and needed treatment at the pediatric intensive care unit.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27962456.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


27. Grugel L, Streicher B, Lang-Roth R, Walger M, von Wedel H, Meister H: [Development of a German version of the Functioning After Pediatric Cochlear Implantation (FAPCI) questionnaire]. HNO; 2009 Jul;57(7):678-84
MedlinePlus Health Information. consumer health - Hearing Disorders and Deafness.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Development of a German version of the Functioning After Pediatric Cochlear Implantation (FAPCI) questionnaire].
  • [Transliterated title] Entwicklung einer deutschsprachigen Version des Fragebogens Functioning After Pediatric Cochlear Implantation (FAPCI).
  • BACKGROUND: The Functioning After Pediatric Cochlear Implantation (FAPCI) instrument was recently developed to determine the communicative performance of 2-5-year-old prelingually deafened, cochlear-implanted children.
  • [MeSH-minor] Child, Preschool. Humans. Male. Reproducibility of Results. Sensitivity and Specificity. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Cochlear Implants.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Klin Padiatr. 2007 Mar-Apr;219(2):76-81 [16917789.001]
  • [Cites] J Speech Hear Disord. 1984 Aug;49(3):226-40 [6748618.001]
  • [Cites] Klin Padiatr. 2007 Jan-Feb;219(1):17-22 [17205428.001]
  • [Cites] Laryngorhinootologie. 2002 Mar;81(3):211-6 [11967774.001]
  • [Cites] Ear Hear. 2007 Sep;28(5):703-12 [17804984.001]
  • [Cites] Laryngorhinootologie. 2005 May;84(5):328-34 [15909244.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2004 May;130(5):570-4 [15148178.001]
  • [Cites] Prax Kinderpsychol Kinderpsychiatr. 2010;59(5):372-88 [20545296.001]
  • (PMID = 19517081.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


28. Kosseva M, Schild S, Wilhelm-Schwenk R, Biewer W, Häuser W: [Comorbid depression mediates the association of childhood/adolescent maltreatment and fibromyalgia syndrome. A study with patients from different clinical settings]. Schmerz; 2010 Sep;24(5):474-84
MedlinePlus Health Information. consumer health - Fibromyalgia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Comorbid depression mediates the association of childhood/adolescent maltreatment and fibromyalgia syndrome. A study with patients from different clinical settings].
  • [Transliterated title] Komorbide depressive Störungen als Mediator der Assoziation von Misshandlungen in Kindheit/Jugend und Fibromyalgiesyndrom. Eine Fallserie von Patienten aus unterschiedlichen klinischen Kontexten.
  • BACKGROUND: Emotional and physical abuse and neglect in childhood and adolescence [childhood maltreatments (CMs)] are considered to play a role in the etiology of fibromyalgia syndrome (FMS).
  • METHODS: CMs of consecutive FMS patients from three different clinical settings were assessed by the German version of the Childhood Trauma Questionnaire.
  • RESULTS: Of 328 patients (86% women, mean age 50 years), 293 were analyzed; 16% of the patients reported severe emotional, 9% severe physical, and 11% severe sexual abuse and 25% severe emotional and 13% severe physical neglect during childhood.
  • [MeSH-major] Child Abuse / psychology. Child Abuse / statistics & numerical data. Depressive Disorder / epidemiology. Depressive Disorder / psychology. Fibromyalgia / epidemiology. Fibromyalgia / psychology
  • [MeSH-minor] Adult. Child. Child Abuse, Sexual / diagnosis. Child Abuse, Sexual / psychology. Child Abuse, Sexual / statistics & numerical data. Comorbidity. Disability Evaluation. Female. Germany. Humans. Male. Middle Aged. Pain Measurement. Personality Inventory. Risk Factors

  • Genetic Alliance. consumer health - Depression.
  • Genetic Alliance. consumer health - Fibromyalgia.
  • MedlinePlus Health Information. consumer health - Child Abuse.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20872126.001).
  • [ISSN] 1432-2129
  • [Journal-full-title] Schmerz (Berlin, Germany)
  • [ISO-abbreviation] Schmerz
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


29. Berkes A, Kiss M, Kemény C, Mogyorósy G: [Hungarian validation of the cardiac module of the Pediatric Quality of Life Inventory]. Orv Hetil; 2008 Nov 30;149(48):2261-8
MedlinePlus Health Information. consumer health - Mental Health.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hungarian validation of the cardiac module of the Pediatric Quality of Life Inventory].
  • [Transliterated title] A Pediatric Quality of Life Inventory (PedsQL) gyermekkori életminoség-méro kérdoív kardiológiai moduljának magyarországi validálása.
  • The authors report the validation process of the cardiac module of the Pediatric Quality of Life Inventory (PedsQL ) into Hungarian.
  • OBJECTIVE: To adapt and to test a pediatric quality of life questionnaire for measuring HRQL in children with heart disease.
  • RESULTS: According to the results of the pilot-study the psychic domains have a negative influence on general HRQL index in both child and parent-proxy reports in all age groups.
  • Parent-child concordance is depending on the age of the child, there was expressed difference in the psychosocial domains.
  • [MeSH-minor] Activities of Daily Living. Adolescent. Anxiety / etiology. Child. Child, Preschool. Cognition. Cognition Disorders / etiology. Communication. Female. Health Status. Humans. Hungary. Male. Pediatrics. Pilot Projects. Psychometrics. Severity of Illness Index. Sickness Impact Profile


30. Cribier B, Lieber-Mbomeyo A, Lipsker D: [Clinical and histological study of a case of facial Afro-Caribbean childhood eruption (FACE)]. Ann Dermatol Venereol; 2008 Oct;135(10):663-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical and histological study of a case of facial Afro-Caribbean childhood eruption (FACE)].
  • [Transliterated title] Etude anatomoclinique d'un cas de dermatite périorale granulomateuse de l'enfant (FACE: facial Afro-Caribbean childhood eruption).
  • BACKGROUND: The term Facial Afro-Caribbean childhood eruption (FACE) was coined in 1990 to describe a perioral granulomatous eruption in black-skinned children.
  • Biopsy revealed a diffuse granulomatous infiltrate of the dermis comprising histiocytes, multinucleated giant cells and a heavy lymphocytic component.
  • DISCUSSION: This particular type of perioral dermatitis is seen chiefly in male children with black skin.
  • [MeSH-minor] African Continental Ancestry Group. Child. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18929915.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


31. Hiermann P, Fries M, Hückel D, Kiess W, Merkenschlager A: [Regulatory disorders in infancy: data of the leipzig counseling service for parents with infants and toddlers]. Klin Padiatr; 2005 Mar-Apr;217(2):61-7
MedlinePlus Health Information. consumer health - Child Behavior Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Regulationsstörungen in der frühen Kindheit: Ergebnisse der Leipziger Beratungsstelle für Eltern mit Säuglingen und Kleinkindern.
  • CONCLUSIONS: The surveyed data support the assumption, that early childhood intervention provides help briefly and economically.
  • [MeSH-major] Child Behavior Disorders / therapy. Child Guidance / methods. Education / methods
  • [MeSH-minor] Child, Preschool. Follow-Up Studies. Humans. Infant. Infant, Newborn. Outcome Assessment (Health Care). Risk Factors. Single-Parent Family

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15770575.001).
  • [ISSN] 0300-8630
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


32. Jenneck C, Foelster-Holst R, Hagemann T, Novak N: [Associated diseases and differential diagnostic considerations in childhood atopic eczema]. Hautarzt; 2007 Feb;58(2):163-74; quiz 175-6
Genetic Alliance. consumer health - Eczema.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Associated diseases and differential diagnostic considerations in childhood atopic eczema].
  • [Transliterated title] Differenzialdiagnose des atopischen Ekzems in der Kindheit. Erkrankungen und Syndrome in Assoziation.
  • [MeSH-minor] Child. Child, Preschool. Chronic Disease. Diagnosis, Differential. Humans. Infant

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Hum Genet. 2000 Mar;66(3):914-21 [10712206.001]
  • [Cites] Pediatrics. 2005 Aug;116(2):e229-34 [16061575.001]
  • [Cites] J Pediatr. 2006 Feb;148(2):272-4 [16492442.001]
  • [Cites] Acta Derm Venereol. 2004;84(5):410-12 [15503364.001]
  • [Cites] J Pathol. 2006 Aug;209(4):474-83 [16718746.001]
  • [Cites] Hum Genet. 1987 Apr;75(4):378-80 [2883107.001]
  • [Cites] Mayo Clin Proc. 1995 Jul;70(7):628-33 [7791384.001]
  • [Cites] Curr Opin Allergy Clin Immunol. 2004 Dec;4(6):505-12 [15640691.001]
  • [Cites] Nat Genet. 1996 Aug;13(4):409-16 [8696334.001]
  • [Cites] Pediatr Allergy Immunol. 2006 Aug;17(5):382-8 [16846458.001]
  • [Cites] Br J Dermatol. 1985 Jun;112(6):679-85 [4005167.001]
  • [Cites] Genomics. 1994 Aug;22(3):662-3 [8001986.001]
  • [Cites] Nat Genet. 2006 Mar;38(3):337-42 [16444271.001]
  • [Cites] Immunol Rev. 2000 Dec;178:64-74 [11213808.001]
  • [Cites] Arch Dermatol. 2000 Oct;136(10):1276-7 [11030789.001]
  • [Cites] Dermatol Ther. 2006 Mar-Apr;19(2):73-82 [16669989.001]
  • [Cites] Hum Mutat. 2001 Nov;18(5):375-81 [11668630.001]
  • [Cites] Klin Padiatr. 2006 Jul-Aug;218(4):221-3 [16819703.001]
  • [Cites] Asian Pac J Allergy Immunol. 1999 Sep;17(3):137-41 [10697251.001]
  • [Cites] Nat Genet. 2002 Jul;31(3):239-40 [12068297.001]
  • [Cites] J Allergy Clin Immunol. 2006 Jul;118(1):214-9 [16815158.001]
  • [Cites] Hum Mutat. 2005 Apr;25(4):413 [15776412.001]
  • [Cites] Eur J Clin Invest. 2005 Nov;35(11):718-21 [16269022.001]
  • [Cites] Hautarzt. 2000 Feb;51(2):95-100 [10743581.001]
  • [Cites] Dermatologica. 1989;178(4):202-5 [2767287.001]
  • [Cites] Cell. 1994 Aug 26;78(4):635-44 [8069912.001]
  • [Cites] Clin Exp Immunol. 2005 Feb;139(2):173-5 [15654814.001]
  • [Cites] Hautarzt. 2003 Dec;54(12):1198-202 [14634751.001]
  • [Cites] Ann Dermatol Venereol. 2006 Feb;133(2):139-43 [16508597.001]
  • [Cites] Am J Med Genet. 1999 Jul 16;85(2):179-82 [10406673.001]
  • [Cites] Blood. 2005 Jun 1;105(11):4179-86 [15731174.001]
  • [Cites] N Engl J Med. 1999 Mar 4;340(9):692-702 [10053178.001]
  • [Cites] Hautarzt. 2003 Aug;54(8):713-22 [12942185.001]
  • (PMID = 17268788.001).
  • [ISSN] 0017-8470
  • [Journal-full-title] Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
  • [ISO-abbreviation] Hautarzt
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


33. Richter-Appelt H, Brinkmann L, Schützmann K: [Parental bonding in childhood and psychological symptoms in a sample of adults with intersexuality]. Psychother Psychosom Med Psychol; 2006 Aug;56(8):325-35
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Parental bonding in childhood and psychological symptoms in a sample of adults with intersexuality].
  • [Transliterated title] Elterliche Bindung in der Kindheit und psychische Symptombelastung in einer Stichprobe von Erwachsenen mit Intersexualität.
  • [MeSH-minor] Adult. Child. Child Rearing. Data Collection. Female. Humans. Logistic Models. Male. Psychiatric Status Rating Scales. Surveys and Questionnaires

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16721707.001).
  • [ISSN] 0937-2032
  • [Journal-full-title] Psychotherapie, Psychosomatik, medizinische Psychologie
  • [ISO-abbreviation] Psychother Psychosom Med Psychol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


34. Sodtke D, Armbruster MM: [ELTERN-AG--the low threshold school for parents for the early childhood]. Prax Kinderpsychol Kinderpsychiatr; 2007;56(8):707-20
MedlinePlus Health Information. consumer health - Child Behavior Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [ELTERN-AG--the low threshold school for parents for the early childhood].
  • [Transliterated title] ELTERN-AG-- Die niedrigschwellige Elternschule für die frühe Kindheit.
  • It works with deprived parents from the moment when they plan to get a baby up to their child's school entry.
  • [MeSH-major] Affective Symptoms / prevention & control. Child Abuse / prevention & control. Child Behavior Disorders / prevention & control. Education / methods
  • [MeSH-minor] Adaptation, Psychological. Child. Child, Preschool. Humans. Infant. Object Attachment. Parenting / psychology. Self Efficacy

  • MedlinePlus Health Information. consumer health - Child Abuse.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18051618.001).
  • [ISSN] 0032-7034
  • [Journal-full-title] Praxis der Kinderpsychologie und Kinderpsychiatrie
  • [ISO-abbreviation] Prax Kinderpsychol Kinderpsychiatr
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


35. Hübner B, Hechler T, Dobe M, Damschen U, Kosfelder J, Denecke H, Schroeder S, Zernikow B: [Pain-related disability in adolescents suffering from chronic pain. Preliminary examination of the Pediatric Pain Disability Index (P-PDI)]. Schmerz; 2009 Feb;23(1):20-32
MedlinePlus Health Information. consumer health - Pain.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pain-related disability in adolescents suffering from chronic pain. Preliminary examination of the Pediatric Pain Disability Index (P-PDI)].
  • [Transliterated title] Schmerzbezogene Beeinträchtigung bei Jugendlichen mit chronischen Schmerzen. Erste Uberprüfung des Pediatric Pain Disability Index (P-PDI).
  • The aim of this study was to translate the Pediatric Pain Disability Index (P-PDI) of Varni into German and to investigate its psychometric qualities.
  • [MeSH-minor] Adolescent. Child. Chronic Disease. Combined Modality Therapy. Cross-Sectional Studies. Female. Follow-Up Studies. Humans. Male. Pain Management. Pain Measurement / statistics & numerical data. Principal Component Analysis. Recurrence

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18941801.001).
  • [ISSN] 1432-2129
  • [Journal-full-title] Schmerz (Berlin, Germany)
  • [ISO-abbreviation] Schmerz
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


36. Hardt J, Hoffmann SO: [Childhood in flux--Part II: Modern times until today]. Prax Kinderpsychol Kinderpsychiatr; 2006;55(4):280-92
MedlinePlus Health Information. consumer health - Children's Health.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Childhood in flux--Part II: Modern times until today].
  • [Transliterated title] Kindheit im Wandel--Teil II: Moderne bis heute.
  • Bowlby in the 1950s, it became clear that children of primates need more than air, water and food, namely a relationship between the child and an adult person (attachment).
  • [MeSH-major] Child Abuse / history. Child Care / history. Child Welfare / history. Object Attachment
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Europe. History, 19th Century. History, 20th Century. History, 21st Century. Humans. Infant. United States

  • MedlinePlus Health Information. consumer health - Child Abuse.
  • MedlinePlus Health Information. consumer health - Child Care.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17436561.001).
  • [ISSN] 0032-7034
  • [Journal-full-title] Praxis der Kinderpsychologie und Kinderpsychiatrie
  • [ISO-abbreviation] Prax Kinderpsychol Kinderpsychiatr
  • [Language] ger
  • [Publication-type] English Abstract; Historical Article; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


37. Carvajal-Urueña I, García-Marcos L, Busquets-Monge R, Morales Suárez-Varela M, García de Andoin N, Batlles-Garrido J, Blanco-Quirós A, López-Silvarrey A, García-Hernández G, Guillén-Grimaj F, González-Díaz C, Bellido-Blasco J: [Geographic variation in the prevalence of asthma symptoms in Spanish children and adolescents. International Study of Asthma and Allergies in Childhood (ISAAC) Phase 3, Spain]. Arch Bronconeumol; 2005 Dec;41(12):659-66
MedlinePlus Health Information. consumer health - Asthma in Children.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Geographic variation in the prevalence of asthma symptoms in Spanish children and adolescents. International Study of Asthma and Allergies in Childhood (ISAAC) Phase 3, Spain].
  • [Transliterated title] Variaciones geograficas en la prevalencia de sintomas de asma en los ninos y adolescentes espanoles. International Study of Asthma and Allergies in Childhood (ISAAC) fase III Espana.
  • POPULATION AND METHODS: In 2001 and 2002, the Spanish arm of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase 3 collected information on 28 445 children in the age bracket of 6-7 years in 10 metropolitan areas (A Coruña, Asturias, Barcelona, Bilbao, Cartagena, Castellón, Madrid, Pamplona, San Sebastián, and Valencia) and on 31 257 adolescents in the bracket 13-14 years in 11 areas (the previously named areas plus Valladolid).
  • [MeSH-minor] Adolescent. Age Distribution. Child. Humans. Prevalence. Spain / epidemiology. Surveys and Questionnaires

  • Genetic Alliance. consumer health - Asthma.
  • MedlinePlus Health Information. consumer health - Asthma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16373042.001).
  • [ISSN] 0300-2896
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


38. Viñas Poch F, Jané Ballabriga MC, Canals Sans J, Esparó Hidalgo G, Ballespí Solà S, Doménech-Llaberia E: [Assessment of psychopathology in preschool age children through the Early Childhood Inventory-4 (ECI-4): agreement among parents and teachers]. Psicothema; 2008 Aug;20(3):481-6
MedlinePlus Health Information. consumer health - Mental Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Assessment of psychopathology in preschool age children through the Early Childhood Inventory-4 (ECI-4): agreement among parents and teachers].
  • [Transliterated title] Evaluación de la psicopatología del preescolar mediante el Early Childhood Inventory-4 (ECI-4): concordancia entre padres y maestros.
  • The main purpose of this study is to determine the level of agreement among parents and teachers as informants in each one of the dimensions or diagnostic categories of the Early Childhood Inventory-4 (ECI-4).
  • [MeSH-minor] Child. Child, Preschool. Diagnostic and Statistical Manual of Mental Disorders. Female. Humans. Male. Observer Variation. Prevalence

  • MedlinePlus Health Information. consumer health - Child Mental Health.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18674447.001).
  • [ISSN] 0214-9915
  • [Journal-full-title] Psicothema
  • [ISO-abbreviation] Psicothema
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Spain
  •  go-up   go-down


39. Gansz B, Ständer S, Metze D: [Acral pseudolymphomatous angiokeratoma of children (APACHE)]. Hautarzt; 2005 Mar;56(3):270-2
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Akrale pseudolymphomatöse Angiokeratome der Kindheit (APACHE).

  • MedlinePlus Health Information. consumer health - Foot Injuries and Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Dermatol. 1990 Nov;126(11):1524-5 [2241217.001]
  • [Cites] J Am Acad Dermatol. 2001 Dec;45(6 Suppl):S209-11 [11712061.001]
  • [Cites] J Am Acad Dermatol. 2003 Feb;48(2 Suppl):S15-7 [12582375.001]
  • [Cites] Am J Dermatopathol. 1995 Apr;17(2):209-11 [8600790.001]
  • [Cites] Br J Dermatol. 1991 Apr;124(4):387-8 [2025562.001]
  • [Cites] Br J Dermatol. 2001 Sep;145(3):512-4 [11531852.001]
  • [Cites] Acta Derm Venereol. 2002;82(4):301-2 [12361139.001]
  • [Cites] Am J Dermatopathol. 1994 Apr;16(2):130-3 [8030763.001]
  • [Cites] J Cutan Pathol. 2002 May;29(5):313-8 [12100634.001]
  • (PMID = 15580454.001).
  • [ISSN] 0017-8470
  • [Journal-full-title] Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
  • [ISO-abbreviation] Hautarzt
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


40. Işik N, Balak N, Silav G, Elmaci I: Pediatric intramedullary teratomas. Neuropediatrics; 2008 Aug;39(4):196-9
MedlinePlus Health Information. consumer health - Children's Health.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric intramedullary teratomas.
  • Teratomas account for 3% of all childhood tumors, with the majority occurring in the sacrococcygeal region and in the ovary.
  • [MeSH-minor] Child, Preschool. Female. Humans. Magnetic Resonance Imaging

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19165706.001).
  • [ISSN] 0174-304X
  • [Journal-full-title] Neuropediatrics
  • [ISO-abbreviation] Neuropediatrics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 37
  •  go-up   go-down


41. Lightfoot T: Aetiology of childhood leukemia. Bioelectromagnetics; 2005;Suppl 7:S5-S11
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aetiology of childhood leukemia.
  • Leukemia is the most common cancer to affect children, accounting for approximately a third of all childhood cancers.
  • The major morphological subtypes of leukemia, acute lymphoblastic leukemia (ALL), and acute myeloblastic leukemia (AML), are characterized by chromosomal translocations involving over 200 genes including mixed lineage leukemia (MLL), TEL, and AML1.
  • Chromosomal translocations involving the MLL gene at 11q23 are a common feature of infant acute leukemia, found in up to 80% of all cases, and there is strong evidence that rearrangements involving the MLL gene or the TEL-AML1 gene fusion can originate in utero.
  • As with most other cancers, the mechanism by which leukemia arises is likely to involve gene-environment interactions.
  • Exposures acting before birth and early in life has long been thought to be important determinants of leukemia, and the list of suspected chemical, physical, and biological agents continues to increase.
  • Unfortunately, the evidence regarding the majority of suggested exposures is limited and often contradictory, and there are areas, which clearly warrant further investigation in order to further our understanding of the aetiology of childhood leukemia.
  • [MeSH-major] Electromagnetic Fields / adverse effects. Environmental Exposure / adverse effects. Leukemia, Radiation-Induced / etiology. Leukemia, Radiation-Induced / physiopathology. Prenatal Exposure Delayed Effects / etiology. Prenatal Exposure Delayed Effects / physiopathology
  • [MeSH-minor] Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Models, Biological. Pregnancy. Risk Assessment / methods. Risk Factors

  • MedlinePlus Health Information. consumer health - Electromagnetic Fields.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2005 Wiley-Liss, Inc
  • (PMID = 16059922.001).
  • [ISSN] 0197-8462
  • [Journal-full-title] Bioelectromagnetics
  • [ISO-abbreviation] Bioelectromagnetics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 54
  •  go-up   go-down


42. Whitley E, Gunnell D, Davey Smith G, Holly JM, Martin RM: Childhood circumstances and anthropometry: the Boyd Orr cohort. Ann Hum Biol; 2008 Sep-Oct;35(5):518-34
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Childhood circumstances and anthropometry: the Boyd Orr cohort.
  • BACKGROUND: Childhood environment is known to affect stature in childhood and adulthood.
  • Peak growth for different anthropometric measures occurs at different times and so associations with childhood conditions that vary across different components of stature may indicate periods of growth that are particularly influenced by environmental factors.
  • METHODS: The study examined relationships between anthropometric measurements (foot length, shoulder breadth, height, trunk and leg length) and childhood exposures (breast-feeding, birth order, household income, household food expenditure, social class, crowding, number of children in the household, and household diet) in 2376 members of the Boyd Orr cohort aged 2-14 years.
  • RESULTS: All childhood exposures were associated with childhood anthropometric measures to some degree.
  • CONCLUSIONS: The individual components of stature most strongly associated with childhood environment in this age group were leg and foot length.
  • [MeSH-minor] Adolescent. Age Distribution. Child. Child, Preschool. Cohort Studies. Confidence Intervals. Female. Health Surveys. Humans. Male. Sex Characteristics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18821329.001).
  • [ISSN] 1464-5033
  • [Journal-full-title] Annals of human biology
  • [ISO-abbreviation] Ann. Hum. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


43. Robinson KE, Livesay KL, Campbell LK, Scaduto M, Cannistraci CJ, Anderson AW, Whitlock JA, Compas BE: Working memory in survivors of childhood acute lymphocytic leukemia: functional neuroimaging analyses. Pediatr Blood Cancer; 2010 Apr;54(4):585-90
Hazardous Substances Data Bank. METHOTREXATE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Working memory in survivors of childhood acute lymphocytic leukemia: functional neuroimaging analyses.
  • BACKGROUND: Research on the physical and psychological late effects of treatment of childhood cancer has led to the identification of significant long-term neurocognitive deficits experienced by some survivors, particularly in the areas of memory and executive functioning.
  • PROCEDURE: This study used functional neuroimaging techniques to examine working memory and executive functioning deficits of survivors of childhood acute lymphocytic leukemia (ALL), as compared to age- and gender-matched healthy controls.
  • CONCLUSIONS: These results support the theory of compensatory activation in necessary brain regions in order to complete tasks in pediatric ALL survivors, similar to that observed in multiple sclerosis patients.

  • MedlinePlus Health Information. consumer health - Memory.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CYTARABINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Brain. 2002 Jun;125(Pt 6):1275-82 [12023316.001]
  • [Cites] Med Pediatr Oncol. 2003 Feb;40(2):88-92 [12461791.001]
  • [Cites] Biol Psychiatry. 2003 Mar 1;53(5):376-84 [12614990.001]
  • [Cites] Dev Psychol. 2003 Jul;39(4):761-76 [12859128.001]
  • [Cites] Hum Brain Mapp. 2003 Oct;20(2):51-8 [14505331.001]
  • [Cites] Ann N Y Acad Sci. 2004 Jun;1021:296-309 [15251900.001]
  • [Cites] Eur J Cancer. 2004 Sep;40(14):2082-90 [15341983.001]
  • [Cites] Child Dev. 2004 Sep-Oct;75(5):1357-72 [15369519.001]
  • [Cites] Med Pediatr Oncol. 1997 Jun;28(6):387-400 [9143382.001]
  • [Cites] Neuroimage. 2005 Jan 1;24(1):61-9 [15588597.001]
  • [Cites] Hum Brain Mapp. 2005 May;25(1):46-59 [15846822.001]
  • [Cites] J Neuropsychiatry Clin Neurosci. 2005 Summer;17(3):357-63 [16179658.001]
  • [Cites] Cancer. 2005 Dec 1;104(11 Suppl):2557-64 [16247780.001]
  • [Cites] Hum Brain Mapp. 2006 Jan;27(1):28-36 [16001441.001]
  • [Cites] Hum Brain Mapp. 2006 May;27(5):392-401 [16596654.001]
  • [Cites] Ann N Y Acad Sci. 2006 Dec;1094:226-34 [17347354.001]
  • [Cites] Pediatr Blood Cancer. 2007 Jul;49(1):65-73 [16628558.001]
  • [Cites] AJNR Am J Neuroradiol. 2008 Apr;29(4):792-7 [18184841.001]
  • [Cites] Pediatr Blood Cancer. 2008 Jul;51(1):99-104 [18322925.001]
  • (PMID = 19953649.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA068485-13S4; United States / NCI NIH HHS / CA / P30 CA068485; United States / NCI NIH HHS / CA / CA068485; United States / NCI NIH HHS / CA / P30 CA068485-13S4
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 04079A1RDZ / Cytarabine; YL5FZ2Y5U1 / Methotrexate
  • [Other-IDs] NLM/ NIHMS183910; NLM/ PMC2901833
  •  go-up   go-down


44. Campbell LK, Scaduto M, Van Slyke D, Niarhos F, Whitlock JA, Compas BE: Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia. J Pediatr Psychol; 2009 Apr;34(3):317-27
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia.
  • OBJECTIVE: To examine the role of executive function in coping and behavioral outcomes in childhood acute lymphocytic leukemia (ALL) survivors.
  • Directions for future research on executive function deficits and coping skills in survivors of pediatric ALL are suggested.
  • [MeSH-major] Adaptation, Psychological. Cognition. Emotions. Precursor Cell Lymphoblastic Leukemia-Lymphoma / psychology. Stress, Psychological / etiology. Survivors / psychology
  • [MeSH-minor] Adolescent. Case-Control Studies. Child. Female. Humans. Male. Neuropsychological Tests / statistics & numerical data. Young Adult

  • MedlinePlus Health Information. consumer health - Stress.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Pediatr Hematol Oncol. 2000 May-Jun;22(3):206-13 [10864051.001]
  • [Cites] Pediatr Blood Cancer. 2008 Jul;51(1):99-104 [18322925.001]
  • [Cites] J Pediatr Psychol. 2001 Jan-Feb;26(1):1-9 [11145727.001]
  • [Cites] Psychol Bull. 2001 Jan;127(1):87-127 [11271757.001]
  • [Cites] Psychosom Med. 2002 Jan-Feb;64(1):34-42 [11818584.001]
  • [Cites] J Pediatr Psychol. 2002 Apr-May;27(3):215-26 [11909929.001]
  • [Cites] Pediatrics. 2002 Jul;110(1 Pt 1):42-52 [12093945.001]
  • [Cites] JAMA. 2003 Sep 24;290(12):1583-92 [14506117.001]
  • [Cites] J Clin Oncol. 2003 Dec 1;21(23):4395-401 [14645430.001]
  • [Cites] J Pers Soc Psychol. 1986 Dec;51(6):1173-82 [3806354.001]
  • [Cites] Pediatr Rehabil. 1997 Apr-Jun;1(2):63-76 [9689241.001]
  • [Cites] Arch Neurol. 1998 Dec;55(12):1561-8 [9865801.001]
  • [Cites] Pediatrics. 1999 Jan;103(1):71-8 [9917442.001]
  • [Cites] Neuroreport. 1999 Sep 9;10(13):2817-21 [10511446.001]
  • [Cites] Brain. 2006 Feb;129(Pt 2):333-45 [16364957.001]
  • [Cites] Cancer. 2006 Feb 15;106(4):941-9 [16411228.001]
  • [Cites] Psychooncology. 2006 Jul;15(7):553-66 [16355435.001]
  • [Cites] J Clin Oncol. 2006 Aug 20;24(24):3858-64 [16921038.001]
  • [Cites] Annu Rev Psychol. 2007;58:119-44 [16903804.001]
  • [Cites] J Consult Clin Psychol. 2006 Dec;74(6):1132-42 [17154742.001]
  • [Cites] Ann N Y Acad Sci. 2006 Dec;1094:226-34 [17347354.001]
  • [Cites] Pediatr Blood Cancer. 2007 Jul;49(1):65-73 [16628558.001]
  • [Cites] J Clin Oncol. 2007 Aug 20;25(24):3649-56 [17704415.001]
  • [Cites] J Pediatr Psychol. 2007 Oct;32(9):1055-66 [17698880.001]
  • [Cites] AJNR Am J Neuroradiol. 2008 Apr;29(4):792-7 [18184841.001]
  • [Cites] J Consult Clin Psychol. 2000 Dec;68(6):976-92 [11142550.001]
  • (PMID = 18667478.001).
  • [ISSN] 1465-735X
  • [Journal-full-title] Journal of pediatric psychology
  • [ISO-abbreviation] J Pediatr Psychol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2722127
  •  go-up   go-down


45. Meeker ND, Yang JJ, Schiffman JD: Pharmacogenomics of pediatric acute lymphoblastic leukemia. Expert Opin Pharmacother; 2010 Jul;11(10):1621-32
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacogenomics of pediatric acute lymphoblastic leukemia.
  • IMPORTANCE OF THE FIELD: Pediatric acute lymphoblastic leukemia (ALL) represents one of the best examples of progress in disease treatment and improved outcome based in part upon the incorporation of the principles of pharmacogenomics.
  • Throughout the past several decades, clinical scientists have continued to refine risk stratification in clinical trials with the understanding that individual patients have different subtypes of pediatric ALL that will respond to therapy in different, but predictable ways.
  • AREAS COVERED IN THIS REVIEW: Discussed in this review are the most significant findings from pharmacogenomic studies of pediatric ALL from 1989 to the present.
  • Pharmacogenomic studies related to the drugs commonly used to treat pediatric ALL are covered in detail, including an emphasis on both genome-wide and candidate gene/pathway approaches.
  • TAKE HOME MESSAGE: The outcome for children with pediatric ALL has improved greatly, and this is in part due to the successful integration of data from pharmacogenomic studies into clinical trials.
  • [MeSH-major] Pharmacogenetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • [MeSH-minor] Child. Cytochrome P-450 CYP3A / genetics. Glucocorticoids / therapeutic use. Humans. Methotrexate / therapeutic use. Methyltransferases / genetics. Neoplasm, Residual. Vincristine / therapeutic use

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Hazardous Substances Data Bank. VINCRISTINE .
  • Hazardous Substances Data Bank. METHOTREXATE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20429672.001).
  • [ISSN] 1744-7666
  • [Journal-full-title] Expert opinion on pharmacotherapy
  • [ISO-abbreviation] Expert Opin Pharmacother
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Glucocorticoids; 5J49Q6B70F / Vincristine; EC 1.14.14.1 / CYP3A5 protein, human; EC 1.14.14.1 / Cytochrome P-450 CYP3A; EC 2.1.1.- / Methyltransferases; EC 2.1.1.67 / thiopurine methyltransferase; YL5FZ2Y5U1 / Methotrexate
  • [Number-of-references] 120
  •  go-up   go-down


46. Kuhn A, Hanneken S, Megahed M, Ruzicka T, Neumann NJ: [Extreme photosensitivity since childhood]. Hautarzt; 2006 Jan;57(1):56-8, 60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Extreme photosensitivity since childhood].
  • [Transliterated title] Extreme Photosensitivität seit der Kindheit.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br J Dermatol. 2001 Feb;144(2):292-6 [11251561.001]
  • [Cites] Hautarzt. 2003 Oct;54(10):977-9 [14513247.001]
  • [Cites] J Am Acad Dermatol. 2001 Jul;45(1):86-95 [11423840.001]
  • [Cites] Am J Dermatopathol. 1998 Jun;20(3):225-32 [9650693.001]
  • [Cites] Arch Dermatol. 2000 Aug;136(8):1033-41 [10926740.001]
  • [Cites] Arch Dermatol. 2000 Aug;136(8):1044-9 [10926741.001]
  • [Cites] Arthritis Rheum. 2003 Aug 15;49(4):494-500 [12910555.001]
  • [Cites] J Am Acad Dermatol. 2003 Jun;48(6):901-8 [12789183.001]
  • [Cites] Dermatology. 2003;207(1):93-5 [12835565.001]
  • (PMID = 16440239.001).
  • [ISSN] 0017-8470
  • [Journal-full-title] Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
  • [ISO-abbreviation] Hautarzt
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


47. Dunwell TL, Hesson LB, Pavlova T, Zabarovska V, Kashuba V, Catchpoole D, Chiaramonte R, Brini AT, Griffiths M, Maher ER, Zabarovsky E, Latif F: Epigenetic analysis of childhood acute lymphoblastic leukemia. Epigenetics; 2009 Apr 1;4(3):185-93
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epigenetic analysis of childhood acute lymphoblastic leukemia.
  • We used a chromosome 3 wide NotI microarray for identification of epigenetically inactivated genes in childhood acute lymphoblastic leukemia (ALL).
  • Three novel genes demonstrated frequent methylation in childhood ALL.
  • In our series of childhood ALL BNC1 was frequently methylated in both T (77%) and B-ALL (79%), whilst MSX1 showed T-ALL (25%) specific methylation.
  • The methylation of the above five genes was cancer specific and expression of the genes could be restored in methylated leukemia cell lines treated with 5-aza-2'-deoxycytidine.
  • This is the first report demonstrating frequent epigenetic inactivation of PPP2R3A, FBLN2, THRB, BNC1 and MSX1 in leukemia.
  • [MeSH-major] Chromosomes, Human, Pair 3 / genetics. DNA Methylation. Epigenesis, Genetic. Gene Expression Regulation, Leukemic. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics


48. Nathan PC, Wasilewski-Masker K, Janzen LA: Long-term outcomes in survivors of childhood acute lymphoblastic leukemia. Hematol Oncol Clin North Am; 2009 Oct;23(5):1065-82, vi-vii
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term outcomes in survivors of childhood acute lymphoblastic leukemia.
  • Cure rates for childhood acute lymphoblastic leukemia (ALL) now exceed 80%.
  • Consequently, there is a growing population of survivors of childhood ALL who are at risk for developing late sequelae of their cancer therapy.
  • In this article, the more common, serious late effects of ALL therapy are reviewed, the treatment exposures that predispose some survivors to their development are discussed, and the need for life-long risk-based medical care for all survivors of childhood ALL is emphasized.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality. Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • [MeSH-minor] Child. Humans. Survivors. Time Factors. Treatment Outcome


49. Styczynski J, Kurylak A, Wysocki M: Cytotoxicity of cortivazol in childhood acute lymphoblastic leukemia. Anticancer Res; 2005 May-Jun;25(3B):2253-8
Hazardous Substances Data Bank. PREDNISOLONE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytotoxicity of cortivazol in childhood acute lymphoblastic leukemia.
  • BACKGROUND: Glucocorticoids are the most important group of drugs used in the treatment of childhood acute lymphoblastic leukemia (ALL), however, resistance to this group remains the main obstacle in curing the disease.
  • AIM: Analysis of ex vivo sensitivity to cortivazol and other glucocorticoids in childhood acute lymphoblastic leukemia, as well as the relationship to anticancer therapy outcome.
  • CONCLUSION: Cortivazol has potent antileukemic activity in childhood ALL.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Pregnatrienes / pharmacology
  • [MeSH-minor] Adolescent. Cell Cycle / drug effects. Child. Child, Preschool. Drug Resistance, Neoplasm. Female. Glucocorticoids / pharmacology. Humans. Infant. Lymphocytes / drug effects. Lymphocytes / pathology. Male. Prednisolone / pharmacology. Prognosis

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16158972.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Glucocorticoids; 0 / Pregnatrienes; 9PHQ9Y1OLM / Prednisolone; YM183K0H63 / cortivazol
  •  go-up   go-down


50. Golumbek P: Pharmacologic agents for pediatric neuroimmune disorders. Semin Pediatr Neurol; 2010 Dec;17(4):245-53
MedlinePlus Health Information. consumer health - Peripheral Nerve Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacologic agents for pediatric neuroimmune disorders.
  • Autoimmune diseases make up a significant portion of the acute and chronic caseload of all pediatric neurologists.
  • This article provides an overview of the current therapeutic options as they relate to the more common pediatric neuroimmune disorders.
  • [MeSH-minor] Age Factors. Child. Humans

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21183131.001).
  • [ISSN] 1558-0776
  • [Journal-full-title] Seminars in pediatric neurology
  • [ISO-abbreviation] Semin Pediatr Neurol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  •  go-up   go-down


51. Horton TM, Sposto R, Brown P, Reynolds CP, Hunger SP, Winick NJ, Raetz EA, Carroll WL, Arceci RJ, Borowitz MJ, Gaynon PS, Gore L, Jeha S, Maurer BJ, Siegel SE, Biondi A, Kearns PR, Narendran A, Silverman LB, Smith MA, Zwaan CM, Whitlock JA, ALLNA 2008 Conference: Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference. Pediatr Blood Cancer; 2010 Jul 1;54(7):872-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference.
  • An international panel of 22 pediatric acute lymphocytic leukemia (ALL) experts addressed this issue (www.ALLNA.org).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Wiley-Liss, Inc.
  • [Cites] J Clin Oncol. 2008 Aug 20;26(24):3971-8 [18711187.001]
  • [Cites] Clin Cancer Res. 2009 Feb 15;15(4):1126-32 [19228717.001]
  • [Cites] Blood. 2004 May 15;103(10):3669-76 [14726387.001]
  • [Cites] J Pediatr Hematol Oncol. 1998 Sep-Oct;20(5):431-8 [9787315.001]
  • [Cites] Br J Haematol. 2005 Dec;131(5):579-87 [16351633.001]
  • [Cites] N Engl J Med. 2006 Jan 12;354(2):166-78 [16407512.001]
  • [Cites] Hematol Oncol. 2008 Jun;26(2):73-81 [18324639.001]
  • [Cites] Curr Drug Targets. 2007 Jun;8(6):703-14 [17584026.001]
  • [Cites] Curr Drug Targets. 2007 Jun;8(6):751-9 [17584030.001]
  • [Cites] Semin Oncol. 2007 Dec;34(6 Suppl 5):S13-20 [18086342.001]
  • [Cites] J Clin Oncol. 2008 Jan 10;26(2):190-5 [18182661.001]
  • [Cites] Paediatr Drugs. 2008;10(2):85-92 [18345718.001]
  • [Cites] Blood. 2006 Nov 15;108(10):3262-70 [16857985.001]
  • (PMID = 20127846.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA113775-04; United States / NCI NIH HHS / CA / K23 CA111728; United States / NCI NIH HHS / CA / K23 CA113775; United States / NCI NIH HHS / CA / K23 CA113775-04
  • [Publication-type] Consensus Development Conference; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Number-of-references] 14
  • [Other-IDs] NLM/ NIHMS163748; NLM/ PMC2857540
  •  go-up   go-down


52. Abuidris DO, Ahmed ME, Elgaili EM, Arora RS: Childhood cancer in Sudan: 1999-2007. Trop Doct; 2008 Oct;38(4):208-10
MedlinePlus Health Information. consumer health - Cancer in Children.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Childhood cancer in Sudan: 1999-2007.
  • There is paucity of information on childhood cancer from Sudan with the last studies published more than 20 years ago.
  • This study aims to provide a current picture of childhood cancer in Sudan.
  • Lymphomas (111, 35%), leukaemia (83, 26%) and Wilms' tumour (43, 13%) were the three most common groups of tumours.
  • Thirty percent of all lymphomas were Burkitt's lymphoma; 3.4% of all childhood cancer cases were nasopharyngeal carcinomas.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Male. Sudan / epidemiology. Time Factors

  • Genetic Alliance. consumer health - Childhood Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18820183.001).
  • [ISSN] 0049-4755
  • [Journal-full-title] Tropical doctor
  • [ISO-abbreviation] Trop Doct
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


53. Nakamura M, Shimada K, Ishida E, Higuchi T, Nakase H, Sakaki T, Konishi N: Molecular pathogenesis of pediatric astrocytic tumors. Neuro Oncol; 2007 Apr;9(2):113-23
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular pathogenesis of pediatric astrocytic tumors.
  • Astrocytomas are the most common pediatric brain tumors, accounting for 7%-8% of all childhood cancers.
  • Relatively few studies have been performed on their molecular properties; therefore, classification of pediatric astrocytic tumors into genetic subtypes similar to that of adult tumors remains to be defined.
  • Here, we report an extensive characterization of 44 pediatric astrocytomas--16 diffuse astrocytomas (WHO grade II), 10 anaplastic astrocytomas (WHO grade III), and 18 glioblastomas (WHO grade IV)--in terms of genetic alterations frequently observed in adult astrocytomas.
  • Loss of heterozygosity (LOH) on 1p/19q and 10p/10q was less common in pediatric astrocytic tumors than in those seen in adults, but the frequency of LOH on 22q was comparable, occurring in 44% of diffuse astrocytomas, 40% of anaplastic astrocytomas, and 61% of glioblastomas.
  • Our results suggest some differences in children compared to adults in the genetic pathways leading to the formation of de novo astrocytic tumors.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Chromosomes, Human, Pair 1. Chromosomes, Human, Pair 10. Chromosomes, Human, Pair 19. Chromosomes, Human, Pair 22. DNA Mutational Analysis. Female. Gene Amplification. Genes, p53. Glioblastoma / genetics. Humans. Loss of Heterozygosity. Male. Mutation. PTEN Phosphohydrolase / genetics. Receptor, Epidermal Growth Factor / genetics. Receptor, Platelet-Derived Growth Factor beta / genetics

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Hum Pathol. 1999 Nov;30(11):1284-90 [10571506.001]
  • [Cites] Acta Neuropathol. 2005 Oct;110(4):402-10 [16155764.001]
  • [Cites] Lab Invest. 2000 Jan;80(1):65-72 [10653004.001]
  • [Cites] Brain Pathol. 2000 Apr;10(2):249-59 [10764044.001]
  • [Cites] J Neuropathol Exp Neurol. 2000 Jun;59(6):539-43 [10850866.001]
  • [Cites] Lab Invest. 2001 Jan;81(1):77-82 [11204276.001]
  • [Cites] Cancer Res. 2001 Mar 1;61(5):2124-8 [11280776.001]
  • [Cites] Am J Pathol. 2001 Apr;158(4):1253-62 [11290543.001]
  • [Cites] Brain Pathol. 2001 Apr;11(2):159-68 [11303791.001]
  • [Cites] Carcinogenesis. 2001 Oct;22(10):1715-9 [11577014.001]
  • [Cites] Childs Nerv Syst. 2001 Sep;17(9):503-11 [11585322.001]
  • [Cites] J Neuropathol Exp Neurol. 2001 Nov;60(11):1099-104 [11706939.001]
  • [Cites] Cancer. 2001 Dec 15;92(12):3155-64 [11753995.001]
  • [Cites] J Neuropathol Exp Neurol. 2002 Mar;61(3):215-25; discussion 226-9 [11895036.001]
  • [Cites] Acta Neuropathol. 2002 Mar;103(3):267-75 [11907807.001]
  • [Cites] Curr Treat Options Oncol. 2001 Dec;2(6):529-36 [12057098.001]
  • [Cites] J Neurooncol. 2002 Sep;59(2):117-22 [12241104.001]
  • [Cites] Cancer Res. 2003 Feb 15;63(4):737-41 [12591717.001]
  • [Cites] Brain Pathol. 2004 Apr;14(2):131-6 [15193025.001]
  • [Cites] Cancer Res. 2004 Oct 1;64(19):6892-9 [15466178.001]
  • [Cites] Cancer Res. 1990 May 15;50(10):2987-90 [2334901.001]
  • [Cites] Cancer. 1993 May 15;71(10 Suppl):3229-36 [8490859.001]
  • [Cites] Brain Pathol. 1993 Jan;3(1):19-26 [8269081.001]
  • [Cites] Oncogene. 1994 Mar;9(3):949-54 [8108140.001]
  • [Cites] Neurosurgery. 1994 Feb;34(2):213-9; discussion 219-20 [8177380.001]
  • [Cites] J Neurosurg. 1994 Sep;81(3):427-36 [8057151.001]
  • [Cites] Neurosurgery. 1994 Jun;34(6):967-72; discussion 972-3 [8084407.001]
  • [Cites] Brain Pathol. 1996 Jul;6(3):217-23; discussion 23-4 [8864278.001]
  • [Cites] Neurosurgery. 1996 Feb;38(2):258-64 [8869052.001]
  • [Cites] Cytogenet Cell Genet. 1996;72(2-3):100-12 [8978759.001]
  • [Cites] Cancer Res. 1997 Jan 15;57(2):304-9 [9000573.001]
  • [Cites] Brain Pathol. 1997 Apr;7(2):755-64 [9161727.001]
  • [Cites] J Neuropathol Exp Neurol. 1997 Jul;56(7):782-9 [9210874.001]
  • [Cites] Nat Genet. 1997 Sep;17(1):32-9 [9288095.001]
  • [Cites] Genes Chromosomes Cancer. 1998 May;22(1):9-15 [9591629.001]
  • [Cites] Acta Neuropathol. 1998 Jun;95(6):559-64 [9650746.001]
  • [Cites] J Neuropathol Exp Neurol. 1998 Jul;57(7):684-9 [9690672.001]
  • [Cites] Clin Cancer Res. 1999 Jul;5(7):1786-92 [10430083.001]
  • [Cites] Oncogene. 1999 Jul 15;18(28):4144-52 [10435596.001]
  • [Cites] Lab Invest. 2005 Feb;85(2):165-75 [15592495.001]
  • [Cites] Clin Cancer Res. 1999 Dec;5(12):4085-90 [10632344.001]
  • (PMID = 17327574.001).
  • [ISSN] 1522-8517
  • [Journal-full-title] Neuro-oncology
  • [ISO-abbreviation] Neuro-oncology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor beta; EC 3.1.3.67 / PTEN Phosphohydrolase
  • [Other-IDs] NLM/ PMC1871665
  •  go-up   go-down


54. Fangusaro J: Pediatric high-grade gliomas and diffuse intrinsic pontine gliomas. J Child Neurol; 2009 Nov;24(11):1409-17
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric high-grade gliomas and diffuse intrinsic pontine gliomas.
  • Pediatric high-grade gliomas represent approximately 10% of all pediatric brain tumors.
  • In this review, we present an overview of both pediatric high-grade gliomas and diffuse intrinsic pontine gliomas with a focus on their epidemiology, etiology, presentation, prognostic factors, biology, treatment modalities, outcomes, and future research directions.
  • [MeSH-minor] Child. Humans. Models, Neurological. Neoplasm Staging

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19638636.001).
  • [ISSN] 1708-8283
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 83
  •  go-up   go-down


55. Spinola-Castro AM, Siviero-Miachon AA, Andreoni S, Tosta-Hernandez PD, Macedo CR, Lee ML: Transient hyperglycemia during childhood acute lymphocytic leukemia chemotherapy: an old event revisited. Clin Adv Hematol Oncol; 2009 Jul;7(7):465-72
MedlinePlus Health Information. consumer health - Steroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transient hyperglycemia during childhood acute lymphocytic leukemia chemotherapy: an old event revisited.
  • Hyperglycemia has been described as a common event occurring during acute lymphocytic leukemia chemotherapy.
  • Our goal was to compare clinical and laboratory findings between hyperglycemic episodes occurring during childhood acute lymphocytic leukemia induction chemotherapy.
  • There were no differences in clinical or laboratory variables among groups, although the majority of episodes occurred in pubescents, regardless of the type of glucocorticoid employed.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Glucocorticoids / adverse effects. Hyperglycemia / chemically induced. Neoplasm Recurrence, Local. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • [MeSH-minor] Adolescent. Amylases / blood. Blood Glucose / metabolism. Body Mass Index. Child. Child, Preschool. Female. Humans. Infant. Male. Remission Induction. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Hyperglycemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19701154.001).
  • [ISSN] 1543-0790
  • [Journal-full-title] Clinical advances in hematology & oncology : H&O
  • [ISO-abbreviation] Clin Adv Hematol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Blood Glucose; 0 / Glucocorticoids; EC 3.2.1.- / Amylases
  •  go-up   go-down


56. Babay HA, Twum-Danso K, Kambal AM, Al-Otaibi FE: Bloodstream infections in pediatric patients. Saudi Med J; 2005 Oct;26(10):1555-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bloodstream infections in pediatric patients.
  • OBJECTIVE: Blood stream infection (BSI) is the leading cause of morbidity and mortality in pediatric patients.
  • This study aims to describe the clinical, microbiological characteristics and outcome of BSI in pediatric patients.
  • METHODS: We collected the clinical data from all pediatric patients with positive blood cultures.
  • RESULTS: Two hundred and twenty pediatric patients had BSI, of whom 147 (67%) were males and 71 (32.2%) were from intensive care units (ICUs).
  • Fever was the most common presentation of pediatric patients (26%) with positive blood culture with no apparent focus of infection.
  • Bone and joint infections, cardiac, renal, gastrointestinal diseases, malignancy and surgical cases were other associated clinical diagnoses of BSI in pediatric patients.
  • CONCLUSION: Bloodstream infection is an important cause of morbidity and mortality in pediatric patients.
  • [MeSH-minor] Adolescent. Age Distribution. Child. Child, Preschool. Cohort Studies. Female. Humans. Incidence. Infant. Intensive Care Units, Neonatal. Intensive Care Units, Pediatric. Male. Risk Assessment. Saudi Arabia / epidemiology. Severity of Illness Index. Sex Distribution. Survival Analysis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16228055.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  •  go-up   go-down


57. Cost NG, Lee J, Snodgrass WT, Harrison CB, Wilcox DT, Baker LA: Hernia after pediatric urological laparoscopy. J Urol; 2010 Mar;183(3):1163-7
Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hernia after pediatric urological laparoscopy.
  • There are no known published reports concerning hernia incidence or related factors after pediatric urological laparoscopic interventions.
  • We present our experience with port site incisional hernias following pediatric urological laparoscopy.
  • MATERIALS AND METHODS: We reviewed all pediatric urological laparoscopic procedures performed at Children's Medical Center Dallas from 2000 to 2008.
  • CONCLUSIONS: The incidence of port site hernia after pediatric urological laparoscopy was 3.2%, similar to the reported incidence in adults.
  • While development of hernia after pediatric urological laparoscopy is rare, it is more likely to occur in infants.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Humans. Infant. Retrospective Studies

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
  • [CommentIn] J Urol. 2010 Mar;183(3):1167 [20096875.001]
  • (PMID = 20096869.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


58. Gupta N, Dhawan A, Beri S, D'souza P: Clinical spectrum of pediatric blepharokeratoconjunctivitis. J AAPOS; 2010 Dec;14(6):527-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical spectrum of pediatric blepharokeratoconjunctivitis.
  • METHODS: In this observational, retrospective case series, we reviewed all medical records of pediatric patients presenting to the ophthalmology clinic at the Kalawati Saran Children's Hospital, New Delhi, India from 2003 to 2006.
  • RESULTS: Of 5,012 pediatric patients, 615 (12%) demonstrated features of BKC.
  • CONCLUSIONS: BKC was the commonest diagnosis at consultation among all pediatric referrals.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
  • (PMID = 21093331.001).
  • [ISSN] 1528-3933
  • [Journal-full-title] Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • [ISO-abbreviation] J AAPOS
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


59. O'Connor SM, Boneva RS: Infectious etiologies of childhood leukemia: plausibility and challenges to proof. Environ Health Perspect; 2007 Jan;115(1):146-50
MedlinePlus Health Information. consumer health - Infectious Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infectious etiologies of childhood leukemia: plausibility and challenges to proof.
  • Infections as well as environmental exposures are proposed determinants of childhood acute lymphoblastic leukemia (ALL), particularly common precursor B-cell ALL (cALL).
  • Lines of investigation test hypotheses that cALL is a rarer result of common infection, that it results from uncommon infection, or that it ensues from abnormal immune development; perhaps it requires a preceding prenatal or early childhood insult.
  • Ideally, studies should document that particular infections precede leukemiA and induce malignant transformation.
  • Primarily based on surrogate markers of infectious exposure, indirect evidence from ecologic and epidemiologic studies varies widely, but some suggest that infancy or early childhood infectious exposures might protect against childhood ALL or cALL.
  • Other challenges to proof include the likely time lag between infection and diagnosis, the ubiquity of many infections, the influence of age at infection, and the limitations in laboratory assays; small numbers of cases, inaccurate background leukemia rates, and difficulty tracking mobile populations further affect duster investigations.
  • [MeSH-major] Communicable Diseases / complications. Precursor Cell Lymphoblastic Leukemia-Lymphoma / etiology
  • [MeSH-minor] Child. Humans

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Lancet. 1999 Oct 30;354(9189):1499-503 [10551495.001]
  • [Cites] Br J Cancer. 1999 Nov;81(5):898-9 [10555765.001]
  • [Cites] Br J Cancer. 1997;75(11):1711-3 [9184193.001]
  • [Cites] Br J Cancer. 1997;76(12):1539-45 [9413937.001]
  • [Cites] Br J Cancer. 1998 Feb;77(4):677-8 [9484830.001]
  • [Cites] Br J Cancer. 1998 Feb;77(4):678 [9484831.001]
  • [Cites] Int J Cancer. 1998 Jun 19;79(3):273-7 [9645350.001]
  • [Cites] Cancer Causes Control. 1998 May;9(3):285-98 [9684709.001]
  • [Cites] Br J Cancer. 1998 Sep;78(5):561-5 [9744491.001]
  • [Cites] Lancet. 1998 Nov 21;352(9141):1707-8 [9853465.001]
  • [Cites] Br J Cancer. 1999 Feb;79(3-4):655-7 [10027345.001]
  • [Cites] Eur J Cancer. 1999 Jan;35(1):91-6 [10211094.001]
  • [Cites] Pediatrics. 1987 Jan;79(1):55-60 [3797171.001]
  • [Cites] Leukemia. 1988 Feb;2(2):120-5 [3278171.001]
  • [Cites] N Engl J Med. 1989 Mar 16;320(11):689-95 [2537928.001]
  • [Cites] Ann Intern Med. 1993 Mar 15;118(6):448-54 [8382459.001]
  • [Cites] Leukemia. 1993 Mar;7(3):349-60 [8445941.001]
  • [Cites] BMJ. 1993 Sep 25;307(6907):774 [8219951.001]
  • [Cites] Br J Cancer. 1995 Jan;71(1):1-5 [7819022.001]
  • [Cites] Lancet. 1995 Jul 22;346(8969):252-3 [7616826.001]
  • [Cites] Am J Public Health. 1995 Aug;85(8 Pt 1):1109-12 [7625505.001]
  • [Cites] Br J Cancer. 1997;75(3):457-63 [9020498.001]
  • [Cites] Lancet. 1997 Feb 1;349(9048):344-9 [9024390.001]
  • [Cites] J Immunother. 1997 Mar;20(2):89-100 [9087381.001]
  • [Cites] Am J Epidemiol. 2000 Dec 15;152(12):1136-44 [11130619.001]
  • [Cites] Leukemia. 2001 Mar;15(3):415-21 [11237065.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):4004-9 [11274424.001]
  • [Cites] Cancer Causes Control. 2001 Aug;12(6):483-90 [11519756.001]
  • [Cites] Front Biosci. 2002 Jan 1;7:d268-74 [11779700.001]
  • [Cites] Br J Cancer. 2002 Apr 8;86(7):1064-9 [11953850.001]
  • [Cites] Br J Cancer. 2002 May 6;86(9):1419-24 [11986774.001]
  • [Cites] Br J Cancer. 1999 May;80(3-4):585-90 [10408870.001]
  • [Cites] Br J Cancer. 1999 Jan;79(1):30-3 [10408689.001]
  • [Cites] Blood. 1999 Aug 1;94(3):1057-62 [10419898.001]
  • [Cites] Br J Cancer. 1999 Jul;80(9):1483-9 [10424755.001]
  • [Cites] Eur J Cancer. 1999 Mar;35(3):439-44 [10448296.001]
  • [Cites] Br J Cancer. 1999 Aug;80(11):1844-51 [10468308.001]
  • [Cites] Lancet. 1999 Aug 14;354(9178):532 [10470695.001]
  • [Cites] Br J Cancer. 1999 Sep;81(1):175-8 [10487630.001]
  • [Cites] Br J Cancer. 2004 Nov 29;91(11):1866-72 [15520821.001]
  • [Cites] Int J Cancer. 2005 Jul 1;115(4):599-605 [15700307.001]
  • [Cites] BMJ. 2005 Jun 4;330(7503):1294 [15849205.001]
  • [Cites] Hum Pathol. 2005 Jul;36(7):747-55 [16084943.001]
  • [Cites] Pediatrics. 2005 Nov;116(5):e724-31 [16263987.001]
  • [Cites] J Autoimmun. 2005;25 Suppl:74-80 [16278064.001]
  • [Cites] Haematologica. 2006 Feb;91(2):240-3 [16461310.001]
  • [Cites] Emerg Infect Dis. 2006 Jul;12(7):1051-7 [16836820.001]
  • [Cites] Br J Cancer. 2000 Jan;82(1):234-40 [10638995.001]
  • [Cites] Blood. 2000 Feb 1;95(3):1023-31 [10648418.001]
  • [Cites] Br J Haematol. 2000 Apr;109(1):64-70 [10848783.001]
  • [Cites] JAMA. 2000 Jul 12;284(2):205-9 [10889594.001]
  • [Cites] Br J Cancer. 2000 Dec;83(11):1559-64 [11076669.001]
  • [Cites] Pediatr Blood Cancer. 2004 Apr;42(4):357-60 [14966833.001]
  • [Cites] Med Hypotheses. 2004;62(3):387-91 [14975509.001]
  • [Cites] N Engl J Med. 2004 Mar 25;350(13):1328-37 [15044644.001]
  • [Cites] Rev Clin Exp Hematol. 2003 Dec;7(4):336-61 [15129647.001]
  • [Cites] J Infect Dis. 2004 Jun 15;189(12):2271-81 [15181575.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2004 Aug;13(8):1361-70 [15298959.001]
  • [Cites] Oncogene. 2004 Aug 23;23(38):6341-8 [15322509.001]
  • [Cites] Br J Cancer. 2004 Aug 31;91(5):913-5 [15292925.001]
  • [Cites] Br J Haematol. 2004 Nov;127(3):243-63 [15491284.001]
  • [Cites] Br Med J. 1968 Dec 7;4(5631):604-8 [5247313.001]
  • [Cites] Md State Med J. 1969 Nov;18(11):73-7 passim [5352399.001]
  • [Cites] J Med. 1970;1(3):180-7 [4995531.001]
  • [Cites] J Natl Cancer Inst. 1982 Aug;69(2):333-7 [6287075.001]
  • [Cites] Am J Epidemiol. 1986 Oct;124(4):590-4 [3463201.001]
  • [Cites] Leuk Res. 2002 Jul;26(7):651-6 [12008082.001]
  • [Cites] Med Pediatr Oncol. 2002 Jun;38(6):391-7 [11984799.001]
  • [Cites] Paediatr Perinat Epidemiol. 2002 Apr;16(2):154-65 [12060313.001]
  • [Cites] Med Pediatr Oncol. 2003 Apr;40(4):219-23 [12555248.001]
  • [Cites] Am J Epidemiol. 2003 Aug 1;158(3):207-13 [12882942.001]
  • [Cites] Br J Haematol. 2003 Oct;123(1):60-5 [14510943.001]
  • [Cites] N Engl J Med. 2003 Oct 2;349(14):1324-32 [14523140.001]
  • [Cites] Science. 2003 Oct 17;302(5644):415-9 [14564000.001]
  • [Cites] Br J Cancer. 2004 Jan 12;90(1):139-45 [14710221.001]
  • [Cites] Med Pediatr Oncol. 1999 Nov;33(5):441-3 [10531566.001]
  • (PMID = 17366835.001).
  • [ISSN] 0091-6765
  • [Journal-full-title] Environmental health perspectives
  • [ISO-abbreviation] Environ. Health Perspect.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 86
  • [Other-IDs] NLM/ PMC1817664
  •  go-up   go-down


60. Ievers-Landis CE, Redline S: Pediatric sleep apnea: implications of the epidemic of childhood overweight. Am J Respir Crit Care Med; 2007 Mar 1;175(5):436-41
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric sleep apnea: implications of the epidemic of childhood overweight.
  • Over the last 30 years, the prevalence of overweight across all pediatric age groups and ethnicities has increased substantially, with the current prevalence of overweight among adolescents estimated to be approximately 30%.
  • The rising incidence of pediatric overweight likely will impact the prevalence, presentation, and treatment of childhood OSAS.
  • An increased prevalence of overweight also may impact the response to adenotonsillectomy as a primary treatment for childhood OSAS.
  • The high and anticipated increased prevalence of pediatric OSAS mandates assessment of optimal approaches for preventing and treating both OSAS and overweight across the pediatric age range.
  • In this Pulmonary Perspective, the interrelationships between pediatric OSAS and overweight are reviewed, and the implications of the overweight epidemic on childhood OSAS are discussed.

  • Genetic Alliance. consumer health - Sleep Apnea.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Pediatrics. 2002 Apr;109(4):704-12 [11927718.001]
  • [Cites] Am J Respir Crit Care Med. 2002 Apr 1;165(7):934-9 [11934717.001]
  • [Cites] Child Care Health Dev. 2002 Mar;28(2):163-70 [11952652.001]
  • [Cites] Int J Obes Relat Metab Disord. 2002 May;26(5):710-6 [12032757.001]
  • [Cites] Am J Respir Crit Care Med. 2002 Jun 1;165(11):1499-503 [12045123.001]
  • [Cites] J Pediatr. 2002 Jun;140(6):654-9 [12072866.001]
  • [Cites] Eur J Orthod. 1988 May;10(2):106-10 [3164676.001]
  • [Cites] J Laryngol Otol. 1988 May;102(5):419-22 [3397635.001]
  • [Cites] Adv Pediatr. 1988;35:73-137 [3055868.001]
  • [Cites] Lancet. 1990 Feb 3;335(8684):249-53 [1967719.001]
  • [Cites] Health Psychol. 1990;9(4):435-49 [2373068.001]
  • [Cites] Proc Nutr Soc. 1991 Aug;50(2):139-47 [1749787.001]
  • [Cites] N Engl J Med. 1992 Nov 5;327(19):1350-5 [1406836.001]
  • [Cites] N Engl J Med. 1993 Apr 29;328(17):1230-5 [8464434.001]
  • [Cites] Am Rev Respir Dis. 1993 Jul;148(1):195-200 [8317798.001]
  • [Cites] Pediatrics. 1994 May;93(5):784-8 [8165079.001]
  • [Cites] Pediatrics. 1998 Mar;101(3 Pt 2):497-504 [12224656.001]
  • [Cites] Pediatrics. 1998 Mar;101(3 Pt 2):518-25 [12224658.001]
  • [Cites] JAMA. 2002 Oct 9;288(14):1728-32 [12365956.001]
  • [Cites] Am J Hum Biol. 2002 Nov-Dec;14(6):762-8 [12400037.001]
  • [Cites] Am J Respir Crit Care Med. 2003 Jan 1;167(1):65-70 [12406826.001]
  • [Cites] J Am Acad Child Adolesc Psychiatry. 2003 Feb;42(2):201-8 [12544180.001]
  • [Cites] J Pediatr. 2003 Apr;142(4):377-82 [12712054.001]
  • [Cites] J Pediatr. 2003 Apr;142(4):383-9 [12712055.001]
  • [Cites] JAMA. 2003 May 7;289(17):2230-7 [12734134.001]
  • [Cites] Chest. 2003 Jul;124(1):196-203 [12853523.001]
  • [Cites] Sleep. 2003 Aug 1;26(5):587-91 [12938812.001]
  • [Cites] Am J Respir Crit Care Med. 2003 Sep 1;168(5):522-30 [12746251.001]
  • [Cites] J Appl Physiol (1985). 2003 Nov;95(5):2030-8 [12897029.001]
  • [Cites] Sleep. 2003 Sep15;26(6):703-9 [14572123.001]
  • [Cites] Pediatrics. 2003 Nov;112(5):1138-45 [14595059.001]
  • [Cites] Arch Dis Child. 2003 Dec;88(12):1043-7 [14670764.001]
  • [Cites] Int J Obes Relat Metab Disord. 2003 Dec;27 Suppl 3:S53-5 [14704746.001]
  • [Cites] Am J Respir Crit Care Med. 2004 Apr 15;169(8):950-6 [14764433.001]
  • [Cites] Sleep. 2004 May 1;27(3):480-4 [15164902.001]
  • [Cites] Pediatrics. 2004 Jun;113(6):e564-9 [15173538.001]
  • [Cites] J Pediatr. 2004 Jul;145(1):20-5 [15238901.001]
  • [Cites] Arch Pediatr Adolesc Med. 2004 Oct;158(10):988-94 [15466688.001]
  • [Cites] Circulation. 2004 Oct 19;110(16):2494-7 [15477412.001]
  • [Cites] Am Rev Respir Dis. 1986 Oct;134(4):791-802 [3532889.001]
  • [Cites] Clin Pediatr (Phila). 1987 Feb;26(2):90-2 [3802696.001]
  • [Cites] N Engl J Med. 1997 Sep 25;337(13):869-73 [9302300.001]
  • [Cites] FASEB J. 1997 Oct;11(12):937-45 [9337146.001]
  • [Cites] Pediatr Pulmonol Suppl. 1997;16:123-4 [9443235.001]
  • [Cites] Am J Respir Crit Care Med. 1998 Apr;157(4 Pt 1):1098-103 [9563725.001]
  • [Cites] Pediatrics. 1998 Sep;102(3):E29 [9724677.001]
  • [Cites] Arch Pediatr Adolesc Med. 1999 Jan;153(1):33-7 [9894997.001]
  • [Cites] Chin Med J (Engl). 1998 Mar;111(3):257-60 [10374429.001]
  • [Cites] Sleep. 2004 Sep 15;27(6):1113-20 [15532205.001]
  • [Cites] Sleep. 2004 Sep 15;27(6):1131-8 [15532207.001]
  • [Cites] Pediatrics. 2004 Dec;114(6):1640-8 [15574628.001]
  • [Cites] Ann Intern Med. 2004 Dec 7;141(11):846-50 [15583226.001]
  • [Cites] Pediatr Res. 2005 Jan;57(1):99-107 [15557113.001]
  • [Cites] Pediatr Pulmonol. 2005 Mar;39(3):251-6 [15668932.001]
  • [Cites] Am J Respir Crit Care Med. 2005 Mar 15;171(6):659-64 [15591475.001]
  • [Cites] Circulation. 2005 Apr 19;111(15):1978-84 [15837952.001]
  • [Cites] BMJ. 2005 Jun 11;330(7504):1357 [15908441.001]
  • [Cites] PLoS Med. 2004 Dec;1(3):e62 [15602591.001]
  • [Cites] J Appl Physiol (1985). 2005 Oct;99(4):1592-9 [16160020.001]
  • [Cites] Arch Intern Med. 2005 Nov 14;165(20):2408-13 [16287771.001]
  • [Cites] Sleep. 2005 Nov;28(11):1419-27 [16335483.001]
  • [Cites] Arch Pediatr Adolesc Med. 2006 Feb;160(2):203-10 [16461879.001]
  • [Cites] Obesity (Silver Spring). 2006 Apr;14(4):529-644 [16741264.001]
  • [Cites] Int J Obes (Lond). 2006 Nov;30(11):1585-94 [16801930.001]
  • [Cites] Circulation. 1999 Dec 7;100(23):2332-5 [10587337.001]
  • [Cites] J Dev Behav Pediatr. 2000 Feb;21(1):27-36 [10706346.001]
  • [Cites] Am J Orthod Dentofacial Orthop. 2000 Apr;117(4):479-85 [10756275.001]
  • [Cites] Am J Respir Crit Care Med. 2000 Dec;162(6):2166-71 [11112132.001]
  • [Cites] JAMA. 2000 Dec 20;284(23):3015-21 [11122588.001]
  • [Cites] Int J Obes Relat Metab Disord. 2000 Dec;24(12):1683-8 [11126224.001]
  • [Cites] Am J Med Sci. 2001 Apr;321(4):249-79 [11307867.001]
  • [Cites] Sleep. 2001 May 1;24(3):313-20 [11322714.001]
  • [Cites] Chest. 2001 May;119(5):1393-400 [11348944.001]
  • [Cites] Pediatr Pulmonol. 2001 Sep;32(3):222-7 [11536452.001]
  • [Cites] Sleep. 2001 Nov 1;24(7):823-9 [11683485.001]
  • [Cites] Pediatrics. 2001 Nov;108(5):1149-54 [11694695.001]
  • [Cites] Arch Dis Child. 2002 Jan;86(1):34-7 [11806880.001]
  • [Cites] Sleep. 2002 Feb 1;25(1):59-65 [11833862.001]
  • [Cites] Genet Epidemiol. 2002 Mar;22(3):243-53 [11921084.001]
  • [CommentIn] Am J Respir Crit Care Med. 2007 Nov 15;176(10):1054-5; author reply 1055 [17984311.001]
  • (PMID = 17158283.001).
  • [ISSN] 1073-449X
  • [Journal-full-title] American journal of respiratory and critical care medicine
  • [ISO-abbreviation] Am. J. Respir. Crit. Care Med.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / 1 U54CA116867; United States / NHLBI NIH HHS / HL / HL 070916; United States / NCI NIH HHS / CA / U54CA11687
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Number-of-references] 84
  • [Other-IDs] NLM/ PMC2176093
  •  go-up   go-down


61. Harper JD, Shah SK, Baldwin DD, Moorhead JD: Laparoscopic nephrectomy for pediatric giant hydronephrosis. Urology; 2007 Jul;70(1):153-6
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic nephrectomy for pediatric giant hydronephrosis.
  • OBJECTIVES: To describe our experience with pediatric laparoscopic nephrectomy (LN) and laparoscopic nephroureterectomy (LNU) for giant hydronephrosis.
  • METHODS: A retrospective review was conducted of all pediatric patients undergoing a transperitoneal LN or LNU.
  • CONCLUSIONS: Although pediatric LN and LNU for giant hydronephrosis present unique challenges owing to the large renal volume in a small abdominal cavity, these procedures can be safely performed with careful attention to the altered anatomic relationships.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Retrospective Studies

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17656227.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


62. Von Behren J, Reynolds P, Gunier RB, Rull RP, Hertz A, Urayama KY, Kronish D, Buffler PA: Residential traffic density and childhood leukemia risk. Cancer Epidemiol Biomarkers Prev; 2008 Sep;17(9):2298-301
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Residential traffic density and childhood leukemia risk.
  • BACKGROUND: Exposures to carcinogenic compounds from vehicle exhaust may increase childhood leukemia risk, and the timing of this exposure may be important.
  • METHODS: We examined the association between traffic density and childhood leukemia risk for three time periods: birth, time of diagnosis, and lifetime average, based on complete residential history in a case-control study.
  • RESULTS: We included 310 cases of acute lymphocytic leukemias (ALL) and 396 controls in our analysis.
  • CONCLUSIONS: Living in areas of high traffic density during any of the exposure time periods was not associated with increased risk of childhood ALL in this study.

  • MedlinePlus Health Information. consumer health - Childhood Leukemia.
  • MedlinePlus Health Information. consumer health - Leukemia.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Epidemiol. 2006 Jun 15;163(12):1091-100 [16597704.001]
  • [Cites] Int J Cancer. 2006 Jun 15;118(12):2920-9 [16425269.001]
  • [Cites] J Expo Anal Environ Epidemiol. 2000 Jan-Feb;10(1):66-85 [10703849.001]
  • [Cites] Am J Epidemiol. 2001 Mar 1;153(5):433-43 [11226975.001]
  • [Cites] Cancer Causes Control. 2002 Sep;13(7):665-73 [12296514.001]
  • [Cites] Ann Epidemiol. 2002 Oct;12(7):482-7 [12377426.001]
  • [Cites] Environ Sci Technol. 2002 Dec 15;36(24):5405-10 [12521168.001]
  • [Cites] Environ Health Perspect. 2003 Apr;111(4):663-8 [12676632.001]
  • [Cites] J Expo Anal Environ Epidemiol. 2003 May;13(3):240-6 [12743618.001]
  • [Cites] Int J Cancer. 2004 Feb 10;108(4):596-9 [14696126.001]
  • [Cites] Epidemiology. 2004 Jan;15(1):6-12 [14712141.001]
  • [Cites] Am J Epidemiol. 2004 May 15;159(10):915-21 [15128601.001]
  • [Cites] Am J Epidemiol. 2004 May 15;159(10):922-4; discussion 925 [15128602.001]
  • [Cites] Occup Environ Med. 2004 Sep;61(9):773-8 [15317919.001]
  • [Cites] Am J Epidemiol. 1979 Mar;109(3):273-84 [453167.001]
  • [Cites] Environ Health Perspect. 1989 Jul;82:165-9 [2477239.001]
  • [Cites] Scand J Work Environ Health. 1989 Oct;15(5):360-3 [2477895.001]
  • [Cites] Scand J Work Environ Health. 1998 Feb;24(1):8-11 [9562395.001]
  • [Cites] Cancer Invest. 2005;23(1):60-75 [15779869.001]
  • [Cites] Environ Health Perspect. 2007 Jan;115(1):138-45 [17366834.001]
  • (PMID = 18768496.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA092674-05; United States / NCI NIH HHS / CA / R01-CA92674; United States / NIEHS NIH HHS / ES / R01-ES09137; United States / NIEHS NIH HHS / ES / R01 ES009137; United States / NCI NIH HHS / CA / R01 CA092674-05; United States / NCI NIH HHS / CA / R01 CA092674
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vehicle Emissions
  • [Other-IDs] NLM/ NIHMS93299; NLM/ PMC2706505
  •  go-up   go-down


63. Karremann M, Rausche U, Fleischhack G, Nathrath M, Pietsch T, Kramm CM, Wolff JE: Clinical and epidemiological characteristics of pediatric gliosarcomas. J Neurooncol; 2010 Apr;97(2):257-65
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical and epidemiological characteristics of pediatric gliosarcomas.
  • We studied the clinical relevance of this histological glioblastoma subentity within the pediatric population.
  • We obtained patient data from the German HIT-GBM database, which contains clinical data for more than 600 pediatric patients with centrally reviewed high-grade gliomas.
  • In the whole series of 23 pediatric GS patients, including previously reported cases, the male-to-female-ratio was 1.2:1.
  • GS was found in all pediatric age groups with a median age of 11 years, but there was an unexpectedly high accumulation in infants (6 of 23 <3 years of age, 26%).
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Kaplan-Meier Estimate. Male. Young Adult

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19806321.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


64. Wang PD: Epidemiological trends of childhood tuberculosis in Taiwan, 1998-2005. Int J Tuberc Lung Dis; 2008 Mar;12(3):250-4
MedlinePlus Health Information. consumer health - Tuberculosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiological trends of childhood tuberculosis in Taiwan, 1998-2005.
  • DESIGN: Data on all childhood TB cases in Taipei City from 1998 to 2005 were obtained from the National Tuberculosis Registry Database.
  • Of the 163 childhood TB cases, 52 cases (31.9%) were extra-pulmonary, with the highest proportional rate, of 39.6%, in the 0- 4 years age group.
  • CONCLUSIONS: The increase in childhood TB may be associated with the increase in the incidence of the disease in adults.
  • [MeSH-minor] Child. Child, Preschool. Humans. Incidence. Infant. Retrospective Studies. Taiwan / epidemiology. Tuberculosis, Pulmonary / epidemiology

  • Genetic Alliance. consumer health - Tuberculosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18284828.001).
  • [ISSN] 1027-3719
  • [Journal-full-title] The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
  • [ISO-abbreviation] Int. J. Tuberc. Lung Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  •  go-up   go-down


65. Gheyle L, Keymolen K, Halewijck S, Gordts F: Pediatric tracheotomy: the Universitair Ziekenhuis Brussels' experience. B-ENT; 2008;4(1):1-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric tracheotomy: the Universitair Ziekenhuis Brussels' experience.
  • OBJECTIVE: To investigate indications, features and outcome of pediatric tracheotomy in our ENT department.
  • METHODS: A retrospective chart review of all pediatric patients who underwent tracheotomy between 1992 and 2006 in the Children's Hospital of the Universitair Ziekenhuis Brussel.
  • [MeSH-minor] Airway Obstruction / therapy. Belgium. Child. Child, Preschool. Female. Humans. Infant. Male. Respiration, Artificial. Retrospective Studies

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18500015.001).
  • [ISSN] 1781-782X
  • [Journal-full-title] B-ENT
  • [ISO-abbreviation] B-ENT
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Belgium
  •  go-up   go-down


66. Ng YT, McGregor AL, Duane DC, Jahnke HK, Bird CR, Wheless JW: Childhood mesial temporal sclerosis. J Child Neurol; 2006 Jun;21(6):512-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Childhood mesial temporal sclerosis.
  • The prevalence among all pediatric brain MRI studies was 0.77%.
  • Febrile seizures can occur in association with mesial temporal sclerosis presenting in childhood.
  • [MeSH-minor] Child. Child, Preschool. Electroencephalography. Female. Humans. Infant. Magnetic Resonance Imaging. Male. Prevalence. Retrospective Studies. Sclerosis. Seizures / etiology. Seizures / physiopathology

  • MedlinePlus Health Information. consumer health - Brain Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Epilepsy Curr. 2007 Jul-Aug;7(4):101-2 [17694167.001]
  • (PMID = 16948937.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


67. McJunkin J, Jeyakumar A: Complications in pediatric cochlear implants. Am J Otolaryngol; 2010 Mar-Apr;31(2):110-3
MedlinePlus Health Information. consumer health - Cochlear Implants.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Complications in pediatric cochlear implants.
  • OBJECTIVE: The purpose of this study is to retrospectively review the complications of pediatric patients undergoing cochlear implantation at a tertiary referral center.
  • A retrospective analysis of all pediatric patients (younger than 18 years) who underwent primary cochlear implantation was performed from January 2001 to December 2005.
  • The patients were reviewed for demographic information, type of hearing loss, cochlear implant device, and complications including implant failure, meningitis, hematoma, implant extrusion, cerebrospinal fluid leak, facial palsy, and wound infection.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Follow-Up Studies. Hearing Loss / etiology. Humans. Male. Meningitis / etiology. Postoperative Complications. Prosthesis Failure. Retrospective Studies. Surgical Flaps

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20015728.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


68. Jamroziak K, Robak T: Do polymorphisms in ABC transporter genes influence risk of childhood acute lymphoblastic leukemia? Leuk Res; 2008 Aug;32(8):1173-5
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Do polymorphisms in ABC transporter genes influence risk of childhood acute lymphoblastic leukemia?
  • It is widely accepted that pathogenesis of childhood acute lymphoblastic leukemia (ALL) is related to the interplay between specific environmental exposure and inherited background.
  • Here, we review several recent reports on potential association between single nucleotide polymorphisms (SNPs) in genes encoding for ABC transporters with predisposition to pediatric ALL.
  • [MeSH-major] ATP-Binding Cassette Transporters / genetics. Polymorphism, Single Nucleotide. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] Child. Child, Preschool. Genetic Predisposition to Disease. Humans. P-Glycoprotein / genetics

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Leuk Res. 2008 Aug;32(8):1214-20 [18243305.001]
  • (PMID = 18294687.001).
  • [ISSN] 0145-2126
  • [Journal-full-title] Leukemia research
  • [ISO-abbreviation] Leuk. Res.
  • [Language] eng
  • [Publication-type] Comment; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / P-Glycoprotein
  •  go-up   go-down


69. Levine RL: Inherited susceptibility to pediatric acute lymphoblastic leukemia. Nat Genet; 2009 Sep;41(9):957-8
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inherited susceptibility to pediatric acute lymphoblastic leukemia.
  • Although genome-wide analyses have identified somatic alterations contributing to the pathogenesis of pediatric acute lymphoblastic leukemia (ALL), few studies have identified germline variants conferring risk of this disease.
  • [MeSH-major] Genetic Predisposition to Disease. Precursor Cell Lymphoblastic Leukemia-Lymphoma / etiology
  • [MeSH-minor] Alleles. CCAAT-Enhancer-Binding Proteins / genetics. Case-Control Studies. Cell Line, Transformed. Cell Transformation, Viral. Child. Child, Preschool. Cohort Studies. Core Binding Factor Alpha 2 Subunit / genetics. DNA-Binding Proteins / genetics. Gene Frequency. Genetic Variation. Genome-Wide Association Study. Germ-Line Mutation. Haplotypes. Herpesvirus 4, Human / physiology. Humans. Ikaros Transcription Factor / genetics. Oncogene Proteins, Fusion / genetics. Polymorphism, Single Nucleotide. Risk Factors. Transcription Factors / genetics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19710713.001).
  • [ISSN] 1546-1718
  • [Journal-full-title] Nature genetics
  • [ISO-abbreviation] Nat. Genet.
  • [Language] eng
  • [Publication-type] News
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ARID5B protein, human; 0 / CCAAT-Enhancer-Binding Proteins; 0 / Core Binding Factor Alpha 2 Subunit; 0 / DNA-Binding Proteins; 0 / IKZF1 protein, human; 0 / Oncogene Proteins, Fusion; 0 / TEL-AML1 fusion protein; 0 / Transcription Factors; 142805-41-2 / CEBPE protein, human; 148971-36-2 / Ikaros Transcription Factor
  •  go-up   go-down


70. Fiske EA, Hall JM: Inflicted childhood neurotrauma. ANS Adv Nurs Sci; 2008 Apr-Jun;31(2):E1-8
MedlinePlus Health Information. consumer health - Child Abuse.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inflicted childhood neurotrauma.
  • In this article, we review literature related to inflicted childhood neurotrauma (ICN).
  • [MeSH-major] Child Abuse / statistics & numerical data. Shaken Baby Syndrome / epidemiology
  • [MeSH-minor] Brain Injuries. Child. Child, Preschool. Female. Humans. Incidence. Infant. Male. Risk Factors. Terminology as Topic. United States / epidemiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18497578.001).
  • [ISSN] 1550-5014
  • [Journal-full-title] ANS. Advances in nursing science
  • [ISO-abbreviation] ANS Adv Nurs Sci
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 34
  •  go-up   go-down


71. Kulkarni KP, Marwaha RK: Pattern and implications of therapy abandonment in childhood acute lymphoblastic leukemia. Asian Pac J Cancer Prev; 2010;11(5):1435-6
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pattern and implications of therapy abandonment in childhood acute lymphoblastic leukemia.
  • In this communication we describe the pattern of therapy abandonment and its impact on survival of childhood acute lymphoblastic leukemia at a large tertiary care center in Northern India and discuss remedial measures.
  • [MeSH-major] Medication Therapy Management. Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy. Treatment Refusal. Withholding Treatment

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21198307.001).
  • [ISSN] 2476-762X
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
  •  go-up   go-down


72. Maniar TN, Braunstein I, Keefe S, Hussen S, Abrams T, De Michele A, El-Deiry WS: Childhood ALL and second neoplasms. Cancer Biol Ther; 2007 Oct;6(10):1525-31
MedlinePlus Health Information. consumer health - Breast Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Childhood ALL and second neoplasms.
  • Second malignancies are a significant concern for survivors of childhood acute lymphoblastic leukemia (ALL), in particular patients who have been treated with cranial irradiation.
  • Breast cancer can occur in association with meningioma, but is not thought to be a consequence of treatment for childhood ALL.
  • We describe the molecular genetics and therapy of childhood ALL, the molecular genetics of meningioma, as well as the possible association between meningioma and breast cancer.
  • [MeSH-major] Breast Neoplasms / epidemiology. Meningeal Neoplasms / epidemiology. Meningioma / epidemiology. Neoplasms, Second Primary / epidemiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Male. Risk

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17952026.001).
  • [ISSN] 1555-8576
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 96
  •  go-up   go-down


73. Chang JS, Wiemels JL, Chokkalingam AP, Metayer C, Barcellos LF, Hansen HM, Aldrich MC, Guha N, Urayama KY, Scélo G, Green J, May SL, Kiley VA, Wiencke JK, Buffler PA: Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev; 2010 Sep;19(9):2152-63
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.
  • BACKGROUND: Childhood acute lymphoblastic leukemia (ALL) has been hypothesized to have an infection- and immune-related etiology.
  • The lack of immune priming in early childhood may result in abnormal immune responses to infections later in life and increase ALL risk.
  • METHODS: The current analyses examined the association between childhood ALL and 208 single-nucleotide polymorphisms (SNP) of 29 adaptive immune function genes among 377 ALL cases and 448 healthy controls.
  • This increased risk was stronger among firstborn children of all ethnicities and among non-Hispanic children with less day care attendance, consistent with the hypothesis about the role of early immune modulation in the development of childhood ALL.
  • Haplotype analyses identified additional regions of CD28, FCGR2, GATA3, IL2RA, STAT4, and STAT6 associated with childhood ALL.
  • CONCLUSION: Polymorphisms of genes on the adaptive immunity pathway are associated with childhood ALL risk.
  • IMPACT: Results of this study support an immune-related etiology of childhood ALL.

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2010 AACR.
  • [Cites] Br J Cancer. 2000 Jan;82(1):234-40 [10638995.001]
  • [Cites] Int J Epidemiol. 2010 Jun;39(3):718-32 [20110276.001]
  • [Cites] Am J Epidemiol. 2000 Dec 15;152(12):1136-44 [11130619.001]
  • [Cites] Am J Hum Genet. 2001 Jul;69(1):138-47 [11404819.001]
  • [Cites] Eur J Immunol. 2001 Nov;31(11):3394-402 [11745358.001]
  • [Cites] Int J Epidemiol. 2001 Dec;30(6):1428-37 [11821358.001]
  • [Cites] Br J Cancer. 2002 Apr 8;86(7):1064-9 [11953850.001]
  • [Cites] Br J Cancer. 2002 May 6;86(9):1419-24 [11986774.001]
  • [Cites] Med Pediatr Oncol. 2002 Jun;38(6):391-7 [11984799.001]
  • [Cites] Science. 2002 Jun 21;296(5576):2225-9 [12029063.001]
  • [Cites] Nat Rev Immunol. 2003 Feb;3(2):133-46 [12563297.001]
  • [Cites] Int J Cancer. 2003 Jun 10;105(2):255-60 [12673688.001]
  • [Cites] Nature. 2003 Dec 18;426(6968):789-96 [14685227.001]
  • [Cites] Br J Cancer. 2004 Jan 12;90(1):139-45 [14710221.001]
  • [Cites] Am J Epidemiol. 2004 May 15;159(10):915-21 [15128601.001]
  • [Cites] Immunology. 2004 Jul;112(3):352-63 [15196202.001]
  • [Cites] Am J Phys Anthropol. 1986 Aug;70(4):433-41 [3766713.001]
  • [Cites] Am J Phys Anthropol. 1986 Aug;70(4):489-503 [3766715.001]
  • [Cites] BMJ. 1989 Nov 18;299(6710):1259-60 [2513902.001]
  • [Cites] J Epidemiol Community Health. 1989 Dec;43(4):352-5 [2614325.001]
  • [Cites] Br J Cancer. 1995 Jan;71(1):1-5 [7819022.001]
  • [Cites] J Natl Cancer Inst. 1997 Jul 2;89(13):939-47 [9214673.001]
  • [Cites] Br J Cancer. 1997;76(9):1241-7 [9365177.001]
  • [Cites] J Immunol. 1998 May 15;160(10):4730-7 [9590218.001]
  • [Cites] Vaccine. 1998 Aug-Sep;16(14-15):1415-9 [9711781.001]
  • [Cites] Clin Exp Allergy. 1998 Nov;28 Suppl 5:39-44; discussion 50-1 [9988446.001]
  • [Cites] Br J Cancer. 1999 May;80(3-4):585-90 [10408870.001]
  • [Cites] Br J Cancer. 1999 Aug;80(11):1844-51 [10468308.001]
  • [Cites] Bioinformatics. 2005 Jan 15;21(2):263-5 [15297300.001]
  • [Cites] Paediatr Perinat Epidemiol. 2005 Mar;19(2):152-64 [15787890.001]
  • [Cites] BMJ. 2005 Jun 4;330(7503):1294 [15849205.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Aug;14(8):1928-34 [16103439.001]
  • [Cites] Nucleic Acids Res. 2006 Jan 1;34(Database issue):D617-21 [16381944.001]
  • [Cites] Nat Rev Cancer. 2006 Mar;6(3):193-203 [16467884.001]
  • [Cites] BMC Genet. 2006;7:38 [16774684.001]
  • [Cites] Clin Exp Allergy. 2006 Nov;36(11):1357-66 [17083345.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2006 Dec;15(12):2533-6 [17164381.001]
  • [Cites] Am J Hum Genet. 2007 Feb;80(2):273-90 [17236132.001]
  • [Cites] Am J Epidemiol. 2007 Mar 1;165(5):496-504 [17182983.001]
  • [Cites] Int J Cancer. 2007 Aug 15;121(4):819-24 [17390373.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2007 Aug;16(8):1686-90 [17684147.001]
  • [Cites] Am J Epidemiol. 2008 Mar 1;167(5):598-606 [18079130.001]
  • [Cites] Adv Genet. 2008;60:335-405 [18358327.001]
  • [Cites] Br J Cancer. 2008 Nov 4;99(9):1529-33 [18827817.001]
  • [Cites] Cancer Causes Control. 2000 Apr;11(4):303-7 [10843442.001]
  • (PMID = 20716621.001).
  • [ISSN] 1538-7755
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] ENG
  • [Grant] United States / NIEHS NIH HHS / ES / R01 ES009137-08; United States / NIEHS NIH HHS / ES / ES009137-10; United States / NIEHS NIH HHS / ES / P42 ES004705-22S10023; United States / NIEHS NIH HHS / ES / R01 ES009137-01A1; United States / NIEHS NIH HHS / ES / P42 ES004705-22S20023; United States / NIEHS NIH HHS / ES / ES009137-05S1; United States / NIEHS NIH HHS / ES / P42 ES004705-200023; United States / NIEHS NIH HHS / ES / P42 ES004705-220023; United States / NIEHS NIH HHS / ES / ES009137-02; United States / NIEHS NIH HHS / ES / ES009137-05; United States / NIEHS NIH HHS / ES / ES009137-04; United States / NIEHS NIH HHS / ES / ES009137-01A1; United States / NIEHS NIH HHS / ES / R01 ES009137-02; United States / NIEHS NIH HHS / ES / R01 ES009137-03; United States / NIEHS NIH HHS / ES / P42 ES004705; United States / NCI NIH HHS / CA / R25 CA112355; United States / NIEHS NIH HHS / ES / ES004705-22S30023; United States / NIEHS NIH HHS / ES / R01 ES009137-10S1; United States / NIEHS NIH HHS / ES / ES009137-03S1; United States / NIEHS NIH HHS / ES / R01 ES009137-07; United States / NIEHS NIH HHS / ES / ES004705-190023; United States / NIEHS NIH HHS / ES / ES004705-200023; United States / NIEHS NIH HHS / ES / R01 ES009137-05S1; United States / NIEHS NIH HHS / ES / R01 ES009137-10; United States / NIEHS NIH HHS / ES / ES004705-230023; United States / NIEHS NIH HHS / ES / PS42ES04705; United States / NIEHS NIH HHS / ES / ES004705-210023; United States / NIEHS NIH HHS / ES / ES009137-06A1; United States / NIEHS NIH HHS / ES / P42 ES004705-22S30023; United States / NIEHS NIH HHS / ES / P42 ES004705-210023; United States / NIEHS NIH HHS / ES / R01 ES009137-03S1; United States / NIEHS NIH HHS / ES / P42 ES004705-230023; United States / NIEHS NIH HHS / ES / ES009137-07; United States / NIEHS NIH HHS / ES / R01 ES009137-04; United States / NIEHS NIH HHS / ES / ES009137-09; United States / NIEHS NIH HHS / ES / ES004705-220023; United States / NIEHS NIH HHS / ES / R01ES09137; United States / NIEHS NIH HHS / ES / ES004705-22S10023; United States / NIEHS NIH HHS / ES / R01 ES009137-06A1; United States / NIEHS NIH HHS / ES / ES004705-22S20023; United States / NIEHS NIH HHS / ES / R01 ES009137; United States / NIEHS NIH HHS / ES / ES009137-10S1; United States / NIEHS NIH HHS / ES / R01 ES009137-05; United States / NIEHS NIH HHS / ES / ES009137-03; United States / NIEHS NIH HHS / ES / P42 ES004705-190023; United States / NIEHS NIH HHS / ES / R01 ES009137-09
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS220398; NLM/ PMC3257312
  •  go-up   go-down


74. Sadawaite S, Jijina F, Nair CK, Seth S, Ghosh K: An unusual presentation of pediatric acute lymphoblastic leukemia. Indian J Hematol Blood Transfus; 2008 Jun;24(2):59-62

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An unusual presentation of pediatric acute lymphoblastic leukemia.
  • Acute lymphoblastic leukemia (ALL) is one of the most common hematological malignancies occurring in children.
  • Pediatric ALL patients usually present with symptoms due to cytopenias, fever and bone pains.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Dis Child. 1977 Jul;52(7):530-3 [267448.001]
  • [Cites] Med Pediatr Oncol. 1979;6(1):51-5 [286156.001]
  • [Cites] J Pediatr. 1990 Aug;117(2 Pt 1):233-7 [2380822.001]
  • [Cites] N Engl J Med. 2000 Oct 19;343(16):1168-76 [11036124.001]
  • [Cites] Pediatr Hematol Oncol. 1998 Mar-Apr;15(2):121-33 [9592839.001]
  • [Cites] Cancer. 1988 Feb 1;61(3):589-92 [3276382.001]
  • [Cites] Pediatr Radiol. 1985;15(4):245-8 [3858787.001]
  • [Cites] J Pediatr Orthop. 1994 Jan-Feb;14(1):105-11 [8113359.001]
  • [Cites] Orthop Clin North Am. 1996 Jul;27(3):635-44 [8649744.001]
  • (PMID = 23100945.001).
  • [ISSN] 0971-4502
  • [Journal-full-title] Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
  • [ISO-abbreviation] Indian J Hematol Blood Transfus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3453041
  • [Keywords] NOTNLM ; ALL / Fracture / Osteoporosis
  •  go-up   go-down


75. Azevedo-Silva F, Reis Rde S, Santos Mde O, Luiz RR, Pombo-de-Oliveira MS: Evaluation of childhood acute leukemia incidence and underreporting in Brazil by capture-recapture methodology. Cancer Epidemiol; 2009 Dec;33(6):403-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of childhood acute leukemia incidence and underreporting in Brazil by capture-recapture methodology.
  • Childhood acute lymphoblastic leukemia (ALL) is said to have lower incidence in developing countries, which has implications for its pathogenesis, but there are few studies concerning the completeness of cancer registries in developing countries.
  • This study analyzes the number of cases and incidence of childhood acute lymphoblastic leukemia in three different cities in Brazil and estimates underreporting cases and possible PBCR failures.
  • METHODS: We evaluated the completeness of PBCR and the incidence rates of childhood ALL from three different Brazilian cities using the two-source capture-recapture method.
  • The estimated completeness of childhood ALL in PBCRs was 15.5%, 35.4% and 29.2%, respectively, for Salvador, Recife and Belo Horizonte.
  • CONCLUSIONS: There was a high estimated underreporting of childhood leukemia cases in some Brazilian cities.
  • Childhood acute lymphoblastic leukemia incidence rates are similar to those of developed countries.
  • [MeSH-major] Disease Notification / statistics & numerical data. Population Surveillance. Precursor Cell Lymphoblastic Leukemia-Lymphoma / epidemiology
  • [MeSH-minor] Adolescent. Brazil / epidemiology. Child. Child, Preschool. Female. Humans. Incidence. Infant. Male. Registries

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Cancer Epidemiol. 2009 Dec;33(6):401-2 [19932647.001]
  • (PMID = 19833572.001).
  • [ISSN] 1877-783X
  • [Journal-full-title] Cancer epidemiology
  • [ISO-abbreviation] Cancer Epidemiol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  •  go-up   go-down


76. Ramchandren S, Leonard M, Mody RJ, Donohue JE, Moyer J, Hutchinson R, Gurney JG: Peripheral neuropathy in survivors of childhood acute lymphoblastic leukemia. J Peripher Nerv Syst; 2009 Sep;14(3):184-9
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peripheral neuropathy in survivors of childhood acute lymphoblastic leukemia.
  • Acute lymphoblastic leukemia (ALL) is the most common form of cancer in children.
  • Thirty-seven survivors of childhood ALL aged 8-18 underwent evaluation for neuropathy through self-reported symptoms, standardized examinations, and nerve conduction studies (NCS).

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.
  • MedlinePlus Health Information. consumer health - Peripheral Nerve Disorders.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Neurology. 1999 Nov 10;53(8):1660-4 [10563609.001]
  • [Cites] Ann Oncol. 2000 Jun;11(6):743-7 [10942065.001]
  • [Cites] Eur J Paediatr Neurol. 2000;4(5):225-33 [11030069.001]
  • [Cites] Cancer. 2002 Apr 1;94(7):2090-106 [11932914.001]
  • [Cites] Neurology. 2003 Nov 11;61(9):1297-300 [14610145.001]
  • [Cites] Neurology. 1969 Apr;19(4):367-74 [5813374.001]
  • [Cites] Clin Sci. 1970 Apr;38(4):23P-24P [5428794.001]
  • [Cites] Brain. 1973;96(1):69-86 [4348690.001]
  • [Cites] Cancer. 1981 Jan 1;47(1):207-14 [7459811.001]
  • [Cites] Ann Neurol. 1980 Dec;8(6):590-6 [7212646.001]
  • [Cites] Am J Clin Oncol. 1982 Dec;5(6):649-55 [7165009.001]
  • [Cites] Brain. 1985 Dec;108 ( Pt 4):861-80 [4075076.001]
  • [Cites] Cancer Invest. 1990;8(2):147-59 [2400936.001]
  • [Cites] Neurology. 1992 Jul;42(7):1367-70 [1620347.001]
  • [Cites] Eur J Pediatr. 1993 Feb;152(2):115-9 [8444217.001]
  • [Cites] Cancer. 1995 Apr 15;75(8):2186-95 [7697611.001]
  • [Cites] Electroencephalogr Clin Neurophysiol. 1995 Oct;97(5):208-14 [7489681.001]
  • [Cites] Pediatr Neurol. 1995 Nov;13(4):314-8 [8771166.001]
  • [Cites] Med Pediatr Oncol. 1996 Dec;27(6):551-5 [8888816.001]
  • [Cites] Support Care Cancer. 2004 Sep;12(9):619-25 [15258838.001]
  • [Cites] Muscle Nerve. 2005 Jan;31(1):113-23 [15536624.001]
  • [Cites] Phys Ther. 2005 Aug;85(8):782-90 [16048425.001]
  • [Cites] N Engl J Med. 2006 Jan 12;354(2):166-78 [16407512.001]
  • [Cites] J Peripher Nerv Syst. 2006 Jun;11(2):135-41 [16787511.001]
  • [Cites] Cancer. 2006 Sep 15;107(6):1303-12 [16894525.001]
  • [Cites] Sleep Med. 2007 Mar;8(2):149-55 [17236808.001]
  • [Cites] J Peripher Nerv Syst. 2007 Sep;12(3):210-5 [17868248.001]
  • [Cites] Pediatr Blood Cancer. 2007 Nov;49(6):841-5 [16960868.001]
  • [Cites] J Peripher Nerv Syst. 2008 Mar;13(1):27-46 [18346229.001]
  • [Cites] Blood. 2008 Sep 1;112(5):1593-9 [18574024.001]
  • [Cites] Leuk Lymphoma. 2008 Aug;49(8):1603-9 [18766974.001]
  • [Cites] Cancer Res. 1973 Jun;33(6):1258-64 [4352365.001]
  • (PMID = 19909482.001).
  • [ISSN] 1529-8027
  • [Journal-full-title] Journal of the peripheral nervous system : JPNS
  • [ISO-abbreviation] J. Peripher. Nerv. Syst.
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / K23 NS072279; United States / NINDS NIH HHS / NS / T32 NS07222-23; United States / NINDS NIH HHS / NS / T32 NS007222; United States / NHLBI NIH HHS / HL / K03 HL04108; United States / NHLBI NIH HHS / HL / K30 HL004108
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 5J49Q6B70F / Vincristine
  • [Other-IDs] NLM/ NIHMS529407; NLM/ PMC3865985
  •  go-up   go-down


77. Settin A, Al Haggar M, Al Dosoky T, Al Baz R, Abdelrazik N, Fouda M, Aref S, Al-Tonbary Y: Prognostic cytogenetic markers in childhood acute lymphoblastic leukemia. Indian J Pediatr; 2007 Mar;74(3):255-63
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic cytogenetic markers in childhood acute lymphoblastic leukemia.
  • OBJECTIVE: To evaluate children with acute lymphoblastic leukemia (ALL) showing resistance to immediate induction chemotherapy in relation to conventional and advanced cytogenetic analysis.
  • CONCLUSION: Some cytogenetic and molecular characterizations of childhood ALL could add prognostic criteria for proper therapy allocation.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Cytogenetic Analysis. Female. Humans. Infant. Male. Prognosis

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17401264.001).
  • [ISSN] 0973-7693
  • [Journal-full-title] Indian journal of pediatrics
  • [ISO-abbreviation] Indian J Pediatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  •  go-up   go-down


78. Watanabe A: [Recent advance in treatment of childhood acute lymphoblastic leukemia]. Gan To Kagaku Ryoho; 2007 Feb;34(2):150-5
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Recent advance in treatment of childhood acute lymphoblastic leukemia].
  • The five-year event-free survival of nearly 80% in childhood acute lymphoblastic leukemia (ALL) achieved in the 1990 s attested to the effectiveness of risk-directed therapy developed through well-designed clinical trials by 4 groups in clinical study, containing CCLSG, TCCSG, KYCCSG and JACLS.
  • Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) was organized in 2003 and includes all four clinical study groups in Japan.
  • The 2004 ALL protocol of Childhood Cancer and Leukemia Group in Japan (CCLSG) contained a new 2-step stratification based on initial age/WBC count and minimal residual disease at day 91.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • [MeSH-minor] Antineoplastic Protocols. Child. Child, Preschool. Humans. Infant. Leukocyte Count. Prognosis. Survival Rate

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17301519.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


79. Kanter RK, Dexter F: Criteria for identification of comprehensive pediatric hospitals and referral regions. J Pediatr; 2005 Jan;146(1):26-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Criteria for identification of comprehensive pediatric hospitals and referral regions.
  • OBJECTIVE: To identify comprehensive pediatric hospitals on the basis of publicly available data.
  • STUDY DESIGN: We developed identification criteria for comprehensive pediatric hospitals, then evaluated the number of hospitals meeting these selection criteria.
  • Criteria for a comprehensive pediatric hospital included pediatric residency accreditation, pediatric inpatient volume, and diversity of pediatric disorders at each hospital.
  • Through the use of higher selective criteria (educational accreditation plus both high volume and diversity in the top decile), 11 comprehensive pediatric hospitals were identified.
  • These hospitals serve populations of 1.7 +/- 0.3 million (mean +/- SD) each, with 8 referral regions throughout the state, collectively providing care for 29% of all pediatric statewide hospitalizations.
  • CONCLUSIONS: Comprehensive pediatric hospitals serve the population of New York widely and evenly.
  • The ability to identify pediatric hospitals will permit evaluation of the relative quality of care and suggest appropriate regulatory interventions to improve pediatric hospital utilization.
  • [MeSH-major] Comprehensive Health Care. Hospitals, Pediatric / statistics & numerical data
  • [MeSH-minor] Accreditation / statistics & numerical data. Child. Diagnosis-Related Groups / statistics & numerical data. Health Services Accessibility. Humans. Infant. New York. Patient Discharge / statistics & numerical data. Referral and Consultation / statistics & numerical data

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] J Pediatr. 2005 Jan;146(1):123-7 [15644836.001]
  • (PMID = 15644817.001).
  • [ISSN] 0022-3476
  • [Journal-full-title] The Journal of pediatrics
  • [ISO-abbreviation] J. Pediatr.
  • [Language] eng
  • [Publication-type] Comment; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


80. Rull RP, Gunier R, Von Behren J, Hertz A, Crouse V, Buffler PA, Reynolds P: Residential proximity to agricultural pesticide applications and childhood acute lymphoblastic leukemia. Environ Res; 2009 Oct;109(7):891-9
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Residential proximity to agricultural pesticide applications and childhood acute lymphoblastic leukemia.
  • Ambient exposure from residential proximity to applications of agricultural pesticides may contribute to the risk of childhood acute lymphoblastic leukemia (ALL).
  • Using residential histories collected from the families of 213 ALL cases and 268 matched controls enrolled in the Northern California Childhood Leukemia Study, the authors assessed residential proximity within a half-mile (804.5m) of pesticide applications by linking address histories with reports of agricultural pesticide use.
  • Proximity was ascertained during different time windows of exposure, including the first year of life and the child's lifetime through the date of diagnosis for cases or reference for controls.
  • These findings suggest future directions for the identification of specific pesticides that may play a role in the etiology of childhood leukemia.

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.
  • MedlinePlus Health Information. consumer health - Pesticides.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Environ Contam Toxicol. 2006 Jan;50(1):31-44 [16237496.001]
  • [Cites] Radiat Prot Dosimetry. 2008;132(2):148-55 [18930927.001]
  • [Cites] Am J Epidemiol. 2006 Apr 15;163(8):743-53 [16495467.001]
  • [Cites] Am J Epidemiol. 2006 Jun 15;163(12):1091-100 [16597704.001]
  • [Cites] Environ Health Perspect. 2006 Jun;114(6):893-7 [16759991.001]
  • [Cites] Am J Epidemiol. 2006 Aug 1;164(3):212-21 [16760223.001]
  • [Cites] J Expo Sci Environ Epidemiol. 2006 Sep;16(5):387-96 [16249796.001]
  • [Cites] Ann Occup Hyg. 2007 Jan;51(1):53-65 [16984946.001]
  • [Cites] Int J Occup Med Environ Health. 2006;19(3):152-69 [17252666.001]
  • [Cites] Environ Health Perspect. 2007 Jan;115(1):138-45 [17366834.001]
  • [Cites] Environ Health Perspect. 2007 May;115(5):684-9 [17520053.001]
  • [Cites] Environ Sci Technol. 2007 May 1;41(9):3233-40 [17539531.001]
  • [Cites] J Expo Sci Environ Epidemiol. 2007 Jul;17(4):331-49 [16736054.001]
  • [Cites] Environ Health Perspect. 2002 Aug;110(8):829-33 [12153767.001]
  • [Cites] Environ Health Perspect. 2002 Sep;110(9):955-60 [12204832.001]
  • [Cites] J Expo Anal Environ Epidemiol. 2002 Nov;12(6):433-40 [12415492.001]
  • [Cites] J Expo Anal Environ Epidemiol. 2003 Jan;13(1):42-50 [12595883.001]
  • [Cites] Environ Health Perspect. 2003 Apr;111(4):389-94 [12676588.001]
  • [Cites] Environ Health Perspect. 2003 Jun;111(8):994-1006 [12826473.001]
  • [Cites] Environ Health Perspect. 2003 Oct;111(13):1582-9 [14527836.001]
  • [Cites] Am J Epidemiol. 2004 May 15;159(10):915-21 [15128601.001]
  • [Cites] Leuk Res. 2004 Sep;28(9):905-6 [15234565.001]
  • [Cites] Leuk Res. 2004 Sep;28(9):947-58 [15234572.001]
  • [Cites] J Occup Med. 1987 May;29(5):451-4 [3598737.001]
  • [Cites] Proc Natl Acad Sci U S A. 1989 Jun;86(12):4715-9 [2734315.001]
  • [Cites] IARC Monogr Eval Carcinog Risks Hum. 1991;53:5-586 [1688189.001]
  • [Cites] Arch Environ Contam Toxicol. 1994 Jan;26(1):47-59 [8110023.001]
  • [Cites] Environ Health Perspect. 1993 Oct;101(5):378-84 [8080506.001]
  • [Cites] Environ Health Perspect. 1995 Dec;103(12):1126-34 [8747019.001]
  • [Cites] Environ Health Perspect. 1997 Oct;105(10):1068-77 [9349828.001]
  • [Cites] Epidemiology. 1999 Sep;10(5):481-7 [10468419.001]
  • [Cites] Epidemiology. 2005 Jan;16(1):93-100 [15613951.001]
  • [Cites] Cancer Invest. 2005;23(1):60-75 [15779869.001]
  • [Cites] J Occup Environ Hyg. 2005 Jul;2(7):357-67 [16020099.001]
  • [Cites] Environ Health Perspect. 2005 Sep;113(9):1184-9 [16140625.001]
  • [Cites] Am J Epidemiol. 2000 Apr 1;151(7):639-46; discussion 647-50 [10752791.001]
  • [Cites] Environ Res. 2000 Nov;84(3):290-302 [11097803.001]
  • [Cites] J Environ Qual. 2001 May-Jun;30(3):697-701 [11401259.001]
  • [Cites] Leuk Res. 2001 Oct;25(10):883-90 [11532522.001]
  • [Cites] Environ Toxicol Chem. 2002 Mar;21(3):659-71 [11878480.001]
  • [Cites] Environ Health Perspect. 2002 Mar;110(3):319-24 [11882484.001]
  • [Cites] Environ Health Perspect. 2002 May;110(5):549-53 [12003762.001]
  • [Cites] Scand J Work Environ Health. 2005;31 Suppl 1:46-54; discussion 5-7 [16190149.001]
  • [Cites] Chem Biol Interact. 2005 Dec 15;157-158:227-32 [16256970.001]
  • [Cites] Scand J Work Environ Health. 2007 Aug;33(4):293-303 [17717622.001]
  • [Cites] J Toxicol Environ Health B Crit Rev. 2007 Jan-Mar;10(1-2):81-99 [18074305.001]
  • [Cites] J Toxicol Environ Health B Crit Rev. 2008 Mar;11(3-4):351-72 [18368561.001]
  • [Cites] Environ Health Perspect. 2008 Apr;116(4):559-65 [18414643.001]
  • [Cites] Occup Environ Med. 2006 Feb;63(2):131-4 [16421392.001]
  • (PMID = 19700145.001).
  • [ISSN] 1096-0953
  • [Journal-full-title] Environmental research
  • [ISO-abbreviation] Environ. Res.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01-CA92674; United States / NIEHS NIH HHS / ES / R01 ES009137-01A1; United States / NIEHS NIH HHS / ES / ES009137-01A1; United States / NCI NIH HHS / CA / R01 CA092674-01A1; United States / NIEHS NIH HHS / ES / R01-ES09137; United States / NCI NIH HHS / CA / CA092674-01A1; United States / NIEHS NIH HHS / ES / R01 ES009137; United States / NCI NIH HHS / CA / R01 CA092674
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Pesticides
  • [Other-IDs] NLM/ NIHMS138328; NLM/ PMC2748130
  •  go-up   go-down


81. Axelrod D, Kazmerski K, Iyer K: Pediatric enteral nutrition. JPEN J Parenter Enteral Nutr; 2006 Jan-Feb;30(1 Suppl):S21-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric enteral nutrition.
  • Common to all pediatric patients receiving enteral nutrition is the inability to consume calories orally.
  • In pediatric patients requiring long-term enteral access, surgically, endoscopically, or radiologically placed percutaneous feeding tubes are common.
  • Jejunal feeding tubes are used in pediatric patients with gastric feeding intolerance or persistent gastroesophageal reflux.
  • Low-profile enteral access devices are preferred by most pediatric patients because of their cosmetic appearance.
  • For most children, a standard pediatric polypeptide enteral formula is well tolerated.
  • There are specialized pediatric enteral formulas available for patients with decreased intestinal length, altered intestinal absorptive capacity, or altered pancreatic function.
  • [MeSH-minor] Child. Child, Preschool. Humans. Infant. Infant, Newborn. Jejunostomy. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16387906.001).
  • [ISSN] 0148-6071
  • [Journal-full-title] JPEN. Journal of parenteral and enteral nutrition
  • [ISO-abbreviation] JPEN J Parenter Enteral Nutr
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
  •  go-up   go-down


82. Liu Y: [Prognosis prediction for childhood acute lymphoblastic leukemia--review]. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2007 Feb;15(1):202-6
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prognosis prediction for childhood acute lymphoblastic leukemia--review].
  • Contemporary risk-directed therapy has advanced the cure rate for childhood acute lymphoblastic leukemia to near 80%.
  • The risk factors and systems of assessment in prognosis prediction for childhood acute lymphoblastic leukemia were summarised in this review.

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17490555.001).
  • [ISSN] 1009-2137
  • [Journal-full-title] Zhongguo shi yan xue ye xue za zhi
  • [ISO-abbreviation] Zhongguo Shi Yan Xue Ye Xue Za Zhi
  • [Language] CHI
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 22
  •  go-up   go-down


83. Stanulla M, Schrappe M: Treatment of childhood acute lymphoblastic leukemia. Semin Hematol; 2009 Jan;46(1):52-63
Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of childhood acute lymphoblastic leukemia.
  • Childhood acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood.
  • Studies in ALL have been a model for clinical and basic research beyond pediatric hemato-oncology.
  • As a result of sustained and well-organized research efforts since the early 1960s, childhood ALL now can be successfully treated in about 80% of patients by the application of intensive combination chemotherapy regimens, which in specific patient subgroups may need to be supplemented with radiation therapy and/or hematopoietic stem cell transplantation.
  • Thus, future research must extend our molecular understanding of leukemia and host factors in order to even more specifically identify the mechanisms underlying the differences in treatment response and outcome, and to finally address the therapeutic needs of the individual child.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • [MeSH-minor] Child. Child, Preschool. Humans. Recurrence. Remission Induction. Treatment Outcome

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19100368.001).
  • [ISSN] 0037-1963
  • [Journal-full-title] Seminars in hematology
  • [ISO-abbreviation] Semin. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 101
  •  go-up   go-down


84. Smith MT, McHale CM, Wiemels JL, Zhang L, Wiencke JK, Zheng S, Gunn L, Skibola CF, Ma X, Buffler PA: Molecular biomarkers for the study of childhood leukemia. Toxicol Appl Pharmacol; 2005 Aug 07;206(2):237-45
Hazardous Substances Data Bank. FOLIC ACID .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular biomarkers for the study of childhood leukemia.
  • Various specific chromosome rearrangements, including t(8;21), t(15;17), and inv(16), are found in acute myeloid leukemia (AML) and in childhood acute lymphocytic leukemia (ALL), t(12;21) and t(1;19) are common.
  • We sequenced the translocation breakpoints of 56 patients with childhood ALL or AML harboring t(12;21), t(8;21), t(15;17), inv(16), and t(1;19), and demonstrated, with the notable exception of t(1;19), that these rearrangements are commonly detected in the neonatal blood spots (Guthrie cards) of the cases.
  • These findings show that most childhood leukemias begin before birth and that maternal and perinatal exposures such as chemical and infectious agents are likely to be critical.
  • Indeed, we have reported that exposure to indoor pesticides during pregnancy and the first year of life raises leukemia risk, but that later exposures do not.
  • We have also examined aberrant gene methylation in different cytogenetic subgroups and have found striking differences between them, suggesting that epigenetic events are also important in the development of some forms of childhood leukemia.
  • Further, at least two studies now show that the inactivating NAD(P)H:quinone acceptor oxidoreductase (NQO1) C609T polymorphism is positively associated with leukemias arising in the first 1-2 years of life and polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene have been associated with adult and childhood ALL.
  • Thus, low folate intake and compounds that are detoxified by NQO1 may be important in elevating leukemia risk in children.
  • Finally, we are exploring the use of proteomics to subclassify leukemia, because cytogenetic analysis is costly and time-consuming.
  • Several proteins have been identified that may serve as useful biomarkers for rapidly identifying different forms of childhood leukemia.
  • [MeSH-major] Leukemia, Myeloid, Acute / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] Biomarkers. Child. DNA Methylation. Folic Acid / metabolism. Gene Expression Profiling. Humans. NAD(P)H Dehydrogenase (Quinone) / genetics. Risk Factors. Translocation, Genetic

  • MedlinePlus Health Information. consumer health - Acute Myeloid Leukemia.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15967214.001).
  • [ISSN] 0041-008X
  • [Journal-full-title] Toxicology and applied pharmacology
  • [ISO-abbreviation] Toxicol. Appl. Pharmacol.
  • [Language] eng
  • [Grant] United States / NIEHS NIH HHS / ES / P42 ES004705; United States / NIEHS NIH HHS / ES / P42ES04705; United States / NIEHS NIH HHS / ES / R01 ES0098137
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 935E97BOY8 / Folic Acid; EC 1.6.5.2 / NAD(P)H Dehydrogenase (Quinone); EC 1.6.5.2 / NQO1 protein, human
  • [Number-of-references] 55
  •  go-up   go-down


85. Nebral K, Denk D, Attarbaschi A, König M, Mann G, Haas OA, Strehl S: Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia. Leukemia; 2009 Jan;23(1):134-43
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia.
  • PAX5, a master regulator of B-cell development, was recently shown to be involved in several leukemia-associated rearrangements, which result in fusion genes encoding chimeric proteins that antagonize PAX5 transcriptional activity.
  • In a population-based fluorescence in situ hybridization screening study of 446 childhood acute lymphoblastic leukemia (ALL) patients, we now show that PAX5 rearrangements occur at an incidence of about 2.5% of B-cell precursor ALL.
  • [MeSH-major] B-Cell-Specific Activator Protein / genetics. Oncogene Proteins, Fusion / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Humans. Infant. Signal Transduction / genetics. Transcription Factors / genetics. Transcription, Genetic. Young Adult

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19020546.001).
  • [ISSN] 1476-5551
  • [Journal-full-title] Leukemia
  • [ISO-abbreviation] Leukemia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / B-Cell-Specific Activator Protein; 0 / Oncogene Proteins, Fusion; 0 / PAX5 protein, human; 0 / Transcription Factors
  •  go-up   go-down


86. Woo HY, Kim DW, Park H, Seong KW, Koo HH, Kim SH: Molecular cytogenetic analysis of gene rearrangements in childhood acute lymphoblastic leukemia. J Korean Med Sci; 2005 Feb;20(1):36-41
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular cytogenetic analysis of gene rearrangements in childhood acute lymphoblastic leukemia.
  • The aims of this study were to estimate the incidences of BCR/ABL, MLL, TEL/AML1 rearrangements, and p16 deletions in childhood acute lymphoblastic leukemia (ALL), to identify new abnormalities, and to demonstrate the usefulness of interphase fluorescence in situ hybridization (FISH).
  • We performed G-banding analysis and FISH using probes for BCR/ABL, MLL, TEL/AML1 rearrangements, and p16 deletions on 65 childhood ALL patients diagnosed and uniformly treated at a single hospital.
  • We established the rough incidences of gene rearrangements in childhood ALL, found new abnormalities and demonstrated the diagnostic capability of interphase FISH to identify cryptic chromosome aberrations.
  • [MeSH-major] Chromosome Aberrations. Cyclin-Dependent Kinase Inhibitor p16 / genetics. DNA-Binding Proteins / genetics. Fusion Proteins, bcr-abl / genetics. Gene Rearrangement. Oncogene Proteins, Fusion / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Proto-Oncogenes / genetics. Transcription Factors / genetics
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Chromosome Banding. Core Binding Factor Alpha 2 Subunit. Female. Gene Deletion. Histone-Lysine N-Methyltransferase. Humans. In Situ Hybridization, Fluorescence. Infant. Interphase. Male. Myeloid-Lymphoid Leukemia Protein. Treatment Outcome

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Hematol Oncol. 1999 Sep;17(3):91-105 [10641030.001]
  • [Cites] Br J Haematol. 1999 Dec;107(3):667-9 [10583273.001]
  • [Cites] Eur J Haematol. 2000 Jul;65(1):40-51 [10914938.001]
  • [Cites] Blood. 2001 Jan 15;97(2):572-4 [11154239.001]
  • [Cites] Genes Chromosomes Cancer. 2001 Apr;30(4):407-9 [11241794.001]
  • [Cites] Cancer Genet Cytogenet. 2001 Apr 1;126(1):73-7 [11343784.001]
  • [Cites] Leuk Lymphoma. 2000 Dec;40(1-2):39-47 [11426627.001]
  • [Cites] Leukemia. 2001 Sep;15(9):1442-7 [11516105.001]
  • [Cites] Br J Haematol. 2001 Sep;114(4):786-93 [11564064.001]
  • [Cites] Genes Chromosomes Cancer. 2001 Nov;32(3):244-9 [11579464.001]
  • [Cites] Eur J Haematol. 2002 Jan;68(1):31-41 [11952819.001]
  • [Cites] Cancer Genet Cytogenet. 2003 Jan 1;140(1):58-61 [12550760.001]
  • [Cites] Genes Chromosomes Cancer. 1993 Aug;7(4):204-8 [7692945.001]
  • [Cites] Br J Cancer. 1996 Feb;73(4):420-3 [8595153.001]
  • [Cites] Blood. 1996 Apr 1;87(7):2891-9 [8639909.001]
  • [Cites] Blood. 1996 Aug 1;88(3):785-94 [8704231.001]
  • [Cites] Blood. 1996 Dec 1;88(11):4252-8 [8943861.001]
  • [Cites] Blood. 1997 Feb 15;89(4):1143-6 [9028935.001]
  • [Cites] Cancer Res. 1997 Mar 1;57(5):907-12 [9041193.001]
  • [Cites] Blood. 1997 Jun 1;89(11):4161-6 [9166859.001]
  • [Cites] Blood. 1997 Jul 15;90(2):571-7 [9226156.001]
  • [Cites] Leukemia. 1997 Sep;11(9):1459-64 [9305598.001]
  • [Cites] Br J Haematol. 1997 Oct;99(1):240-1 [9359534.001]
  • [Cites] Leukemia. 1998 May;12(5):823-7 [9593287.001]
  • [Cites] Leukemia. 1998 Jun;12(6):845-59 [9639410.001]
  • [Cites] Int J Oncol. 1998 Dec;13(6):1319-22 [9824651.001]
  • [Cites] Blood. 1999 Aug 1;94(3):1057-62 [10419898.001]
  • [Cites] Genes Chromosomes Cancer. 1999 Mar;24(3):272-7 [10451708.001]
  • [Cites] Blood. 1999 Sep 1;94(5):1537-44 [10477677.001]
  • [Cites] Leukemia. 1999 Sep;13(9):1325-30 [10482981.001]
  • [Cites] Haematologica. 2000 Apr;85(4):362-6 [10756360.001]
  • (PMID = 15716599.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Core Binding Factor Alpha 2 Subunit; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA-Binding Proteins; 0 / MLL protein, human; 0 / Oncogene Proteins, Fusion; 0 / TEL-AML1 fusion protein; 0 / Transcription Factors; 149025-06-9 / Myeloid-Lymphoid Leukemia Protein; EC 2.1.1.43 / Histone-Lysine N-Methyltransferase; EC 2.7.10.2 / Fusion Proteins, bcr-abl
  • [Other-IDs] NLM/ PMC2808572
  •  go-up   go-down


87. Pui CH: Recent research advances in childhood acute lymphoblastic leukemia. J Formos Med Assoc; 2010 Nov;109(11):777-87
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recent research advances in childhood acute lymphoblastic leukemia.
  • Recent progress in risk-adapted treatment for childhood acute lymphoblastic leukemia has secured 5-year event-free survival rates of approximately 80% and 5-year survival rates approaching 90%.
  • As high-resolution, genome-wide analyses of leukemic and normal host cells continue to identify novel subtypes of lymphoblastic leukemia and provide new insights into leukemogenesis, we can look forward to the time when all cases of this disease will be classified according to specific genetic abnormalities, some of which will yield "druggable" targets for more effective and less toxic treatments.
  • Meanwhile, it is sobering to consider that a significant fraction of leukemia survivors will develop serious health problems within 30 years of their initial diagnosis.
  • The ultimate challenge is to gain a clear understanding of the factors that give rise to childhood leukemia in the first place, and enable preventive strategies to be devised and implemented.

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Formosan Medical Association & Elsevier. Published by Elsevier B.V. All rights reserved.
  • (PMID = 21126650.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA-21765
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Singapore
  •  go-up   go-down


88. Teuffel O, Stanulla M, Cario G, Ludwig WD, Rottgers S, Schafer BW, Zimmermann M, Schrappe M, Niggli FK: Anemia and survival in childhood acute lymphoblastic leukemia. Haematologica; 2008 Nov;93(11):1652-7
Zurich Open Access Repository and Archive. Full text from .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anemia and survival in childhood acute lymphoblastic leukemia.
  • BACKGROUND: Several studies have demonstrated that patients with childhood acute lymphoblastic leukemia presenting with mild anemia at diagnosis have an increased risk of poor outcome compared to patients with more severe anemia.
  • However, it has not been reported whether there is any correlation between degree of anemia and leukemia subtype.
  • DESIGN AND METHODS: In a cohort of 1162 patients with childhood acute lymphoblastic leukemia we analyzed whether there was a correlation between degree of anemia and leukemia subtype.
  • The degree of anemia was significantly different for three distinct groups of patients compared to the remaining patients (mean hemoglobin; T-cell leukemia: 106 g/L versus 76 g/L (precursor B-cell acute lymphoblastic leukemia); within precursor B-cell ALL: TEL-AML1 positive: 68 g/L versus 79 g/L; BCR-ABL positive: 93 g/L versus 76 g/L; each p<0.05).
  • Furthermore, in contrast to the entire study group, patients with T-cell leukemia, TEL-AML1(+), and BCR-ABL(+) precursor B-cell leukemia had a more favorable prognosis if presenting with a higher hemoglobin level (>/=80 g/L).
  • CONCLUSIONS: These observations indicate that the formerly reported direct correlation between severity of anemia and survival in childhood acute lymphoblastic leukemia mainly reflects differences in the degree of anemia between distinct biological subgroups with different treatment outcomes.
  • [MeSH-major] Anemia / epidemiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications. Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • [MeSH-minor] Burkitt Lymphoma / complications. Burkitt Lymphoma / genetics. Burkitt Lymphoma / mortality. Child. Cohort Studies. Core Binding Factor Alpha 2 Subunit / genetics. Disease-Free Survival. Fusion Proteins, bcr-abl / genetics. Hemoglobins / metabolism. Homeodomain Proteins / genetics. Humans. Leukemia, T-Cell / complications. Leukemia, T-Cell / genetics. Leukemia, T-Cell / mortality. Leukocyte Count. Mutation. Oncogene Proteins, Fusion / genetics. Risk Factors. Survival Analysis. Treatment Outcome


89. Aplenc R, Thompson J, Han P, La M, Zhao H, Lange B, Rebbeck T: Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia. Cancer Res; 2005 Mar 15;65(6):2482-7
Hazardous Substances Data Bank. METHOTREXATE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia.
  • A significant portion of patients treated for pediatric acute lymphoblastic leukemia (ALL) relapse.
  • Methotrexate (MTX), which interrupts folate metabolism, is a mainstay of pediatric ALL therapy.
  • These data provide evidence that the MTHFR C677T polymorphism is a common genetic variant conferring a moderate relative risk and a high attributable risk for relapse in pediatric ALL patients.
  • [MeSH-major] Antimetabolites, Antineoplastic / therapeutic use. Methotrexate / therapeutic use. Methylenetetrahydrofolate Reductase (NADPH2) / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / enzymology
  • [MeSH-minor] Alleles. Case-Control Studies. Child, Preschool. Female. Humans. Male. Polymorphism, Genetic


90. Fasano RE, Bergen DC: Intractable epilepsy in patients treated for childhood acute lymphocytic leukemia. Seizure; 2009 May;18(4):298-302
Hazardous Substances Data Bank. METHOTREXATE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intractable epilepsy in patients treated for childhood acute lymphocytic leukemia.
  • PURPOSE: In the 1970s and 80s, standard treatment for childhood acute lymphocytic leukemia (ALL) included both intrathecal methotrexate and whole-brain irradiation.
  • During acute treatment, seizures were not uncommon.
  • We describe five patients who were treated for acute lymphocytic leukemia as children, who later developed intractable epilepsy.
  • RESULTS: All of the patients were diagnosed with leukemia before age seven.
  • CONCLUSIONS: Successful treatment for childhood leukemia may be followed by signs of late cerebral injury including intractable epilepsy.
  • [MeSH-major] Antirheumatic Agents / adverse effects. Cranial Irradiation / adverse effects. Epilepsy / etiology. Methotrexate / adverse effects. Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy

  • Genetic Alliance. consumer health - Epilepsy.
  • MedlinePlus Health Information. consumer health - Epilepsy.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19041267.001).
  • [ISSN] 1059-1311
  • [Journal-full-title] Seizure
  • [ISO-abbreviation] Seizure
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antirheumatic Agents; YL5FZ2Y5U1 / Methotrexate
  •  go-up   go-down


91. Rogers PC, Meacham LR, Oeffinger KC, Henry DW, Lange BJ: Obesity in pediatric oncology. Pediatr Blood Cancer; 2005 Dec;45(7):881-91
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Obesity in pediatric oncology.
  • Its influences on outcomes of childhood cancer are unknown.
  • A recent Children's Oncology Group symposium considered epidemiology of obesity, pharmacology of chemotherapy and outcomes in obese adults with cancer, excess mortality in obese pediatric patients with acute myeloid leukemia (AML), and complications in obese survivors.
  • In the US, obesity prevalence (BMI > 95th centile) is increasing in all pediatric age groups and accelerating fastest among black and Hispanic adolescents.
  • In pediatric acute myeloblastic leukemia, obese patients have greater treatment-related mortality (TRM), similar toxicity and relapse rates, and inferior survival compared with patients who are not obese.
  • An excess of female survivors of childhood leukemia who received cranial irradiation are obese.
  • Ongoing treatment effects of childhood cancer may predispose to a sedentary lifestyle.
  • These findings call for measures to prevent obesity, retrospective and prospective studies of chemotherapy pharmacology of analyzed according to BMI and outcomes, additional studies of the obesity impact on outcomes in pediatric cancer, and promotion of a healthy lifestyle among survivors.
  • [MeSH-major] Leukemia, Myeloid, Acute. Obesity. Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • [MeSH-minor] Adolescent. Adult. Age Factors. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Body Mass Index. Bone Marrow Transplantation. Child. Child, Preschool. Female. Humans. Life Style. Male. Recurrence. Treatment Outcome

  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Acute Myeloid Leukemia.
  • MedlinePlus Health Information. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Obesity in Children.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2005 Wiley-Liss, Inc.
  • (PMID = 16035086.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA 100474-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 81
  •  go-up   go-down


92. Harila MJ, Winqvist S, Lanning M, Bloigu R, Harila-Saari AH: Progressive neurocognitive impairment in young adult survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer; 2009 Aug;53(2):156-61
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Progressive neurocognitive impairment in young adult survivors of childhood acute lymphoblastic leukemia.
  • BACKGROUND: Despite the extensive literature on neuropsychological sequelae after treatment of childhood acute lymphoblastic leukemia (ALL), the very-long-term neurocognitive outcome of the survivors is poorly studied.
  • We assessed neuropsychological functioning in a population-based cohort of young adult childhood ALL survivors.
  • CONCLUSIONS: Survivors of childhood ALL suffer from long-lasting progressive neuropsychological impairment, especially when treatment includes cranial irradiation.
  • [MeSH-major] Brain Neoplasms / complications. Cognition Disorders / epidemiology. Cognition Disorders / etiology. Cranial Irradiation / adverse effects. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • [MeSH-minor] Adolescent. Adult. Age of Onset. Antineoplastic Agents / adverse effects. Child. Child, Preschool. Combined Modality Therapy. Disease Progression. Female. Humans. Infant. Infant, Newborn. Male. Neuropsychological Tests. Survivors. Young Adult


93. Bachmann PS, Gorman R, Papa RA, Bardell JE, Ford J, Kees UR, Marshall GM, Lock RB: Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia. Cancer Res; 2007 May 1;67(9):4482-90
Hazardous Substances Data Bank. DEXAMETHASONE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.
  • Cell line models of glucocorticoid resistance in childhood acute lymphoblastic leukemia (ALL) almost invariably exhibit altered glucocorticoid receptor (GR) function.
  • However, these findings are incongruous with those using specimens derived directly from leukemia patients, in which GR alterations are rarely found.
  • We present a novel paradigm of glucocorticoid resistance in childhood ALL, in which patient biopsies have been directly established as continuous xenografts in immune-deficient mice, without prior in vitro culture.
  • This finding contrasts with five commonly used leukemia cell lines, all of which exhibited defective GRE binding.
  • Furthermore, the receptor tyrosine kinase inhibitor, SU11657, completely reversed dexamethasone resistance in a xenograft expressing functional GR, indicating that pharmacologic reversal of glucocorticoid resistance in childhood ALL is achievable.
  • [MeSH-major] Dexamethasone / pharmacology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Receptors, Glucocorticoid / metabolism
  • [MeSH-minor] Animals. Apoptosis Regulatory Proteins / biosynthesis. Apoptosis Regulatory Proteins / genetics. Child. Gene Expression Regulation, Neoplastic. Humans. Membrane Proteins / biosynthesis. Membrane Proteins / genetics. Mice. Mice, Inbred NOD. Mice, SCID. Organic Chemicals / pharmacology. Proto-Oncogene Proteins / biosynthesis. Proto-Oncogene Proteins / genetics. Receptor Protein-Tyrosine Kinases / antagonists & inhibitors. Transcription Factors / biosynthesis. Transcription Factors / genetics. Transcription, Genetic. Xenograft Model Antitumor Assays

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Glucocorticoid Resistance.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17483364.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / Bcl-2-like protein 11; 0 / Membrane Proteins; 0 / Organic Chemicals; 0 / Proto-Oncogene Proteins; 0 / Receptors, Glucocorticoid; 0 / SU 11657; 0 / TSC22D3 protein, human; 0 / Transcription Factors; 7S5I7G3JQL / Dexamethasone; EC 2.7.10.1 / Receptor Protein-Tyrosine Kinases
  •  go-up   go-down


94. Dengel DR, Ness KK, Glasser SP, Williamson EB, Baker KS, Gurney JG: Endothelial function in young adult survivors of childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol; 2008 Jan;30(1):20-5
Hazardous Substances Data Bank. NITROGLYCERIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endothelial function in young adult survivors of childhood acute lymphoblastic leukemia.
  • BACKGROUND: Adult survivors of childhood acute lymphoblastic leukemia (ALL) have an earlier than expected mortality from cardiovascular disease.
  • This study examined endothelial function in 75 young (age 30.2+/-7.1 y) adult survivors of childhood ALL who received chemotherapy without cranial radiation (n=25) or chemotherapy combined with cranial radiation (n=50) compared with a healthy control group of similar sex, age, and weight (n=59).
  • CONCLUSIONS: These data suggest that young adults treated for ALL during childhood are at risk for impaired FMD regardless of whether or not they received cranial irradiation.
  • The extent to which this mechanism relates to early development of cardiovascular disease in long-term childhood ALL survivors remains to be determined.
  • [MeSH-major] Brachial Artery / physiopathology. Endothelium, Vascular / physiopathology. Nitroglycerin / administration & dosage. Precursor Cell Lymphoblastic Leukemia-Lymphoma / physiopathology. Vasodilation / drug effects. Vasodilator Agents / administration & dosage
  • [MeSH-minor] Adult. Child. Child, Preschool. Cranial Irradiation. Female. Follow-Up Studies. Humans. Male. Sex Factors. Survivors

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia, Childhood.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18176175.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / M01-RR00400; United States / NCI NIH HHS / CA / R21-CA106778; United States / NCI NIH HHS / CA / U24-CA55727
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vasodilator Agents; G59M7S0WS3 / Nitroglycerin
  •  go-up   go-down


95. Bagner DM, Rodrigue JR, Hemme J, Adkins J, Gonzalez-Peralta R: Developmental considerations in the context of pediatric transplantation. Ann Transplant; 2005;10(1):13-6
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Developmental considerations in the context of pediatric transplantation.
  • This paper describes important psychological and psychosocial considerations in pediatric transplantation that can be valuable for all pediatric health care providers in the transplant setting.
  • Appropriate evaluation and referrals are also explained in the context of the pediatric transplant setting.
  • [MeSH-major] Adolescent Development. Child Development. Organ Transplantation / psychology
  • [MeSH-minor] Adolescent. Age Factors. Child. Child, Preschool. Humans. Infant


96. Ivanovski PI, Ivanovski IP: Childhood acute lymphoblastic leukemia is triggered by the introduction of immunization against diphtheria. Med Hypotheses; 2007;68(2):324-7
Genetic Alliance. consumer health - Diphtheria.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Childhood acute lymphoblastic leukemia is triggered by the introduction of immunization against diphtheria.
  • BACKGROUND: Childhood acute lymphoblastic leukemia has prenatal origin.
  • Leukemogenic translocations originating during fetal life are insufficient for overt leukemia.
  • Transgenic TEL-AML1 mice have failed to develop leukemia.
  • Since then, childhood leukemia has almost unchangeable incidence.
  • HYPOTHESIS: Childhood acute lymphoblastic leukemia is triggered by vaccination against diphtheria.
  • TESTING THE HYPOTHESIS: Epidemiological survey for leukemia cases among "exemptors" and unvaccinated cases among ALL children should be done.
  • IMPLICATIONS OF THE HYPOTHESIS: If there is no leukemia among the "exemptors", no unvaccinated among ALL, and some mice develop leukemia upon vaccination childhood leukemia will be prevented by massive neonatal screening for leukemogenic genetics and/or with a new vaccination schedule.
  • [MeSH-major] Diphtheria Toxoid / adverse effects. Precursor Cell Lymphoblastic Leukemia-Lymphoma / etiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology
  • [MeSH-minor] Animals. Child. Disease Models, Animal. Humans. Incidence. Mice


97. Norris RE, Adamson PC: Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias. Cancer Chemother Pharmacol; 2010 May;65(6):1125-30
Hazardous Substances Data Bank. GUANINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias.
  • PURPOSE: Renewed interest in antifols for the treatment of childhood cancers has resulted from identification of novel antifols with broad spectrums of anti-cancer activity and from re-evaluation of the original clinical antifol, aminopterin.
  • In this pre-clinical study we evaluated the in vitro activity of both traditional antifols (methotrexate, aminopterin) and novel antifols (pemetrexed, talotrexin) in childhood acute leukemias and lymphomas.
  • METHODS: We compared the in vitro cytotoxicity of methotrexate, aminopterin, pemetrexed, and talotrexin in a panel of six pediatric leukemia and lymphoma cell lines using the sulforhodamine B assay.
  • We defined each agent's clinical potency index (CPI) as the AUC achieved with standard pediatric dosing regimens divided by the in vitro IC50.
  • CONCLUSIONS: Aminopterin does not appear to offer any advantage over methotrexate for the treatment of childhood ALL.
  • Further study of pemetrexed in childhood leukemias is warranted.
  • [MeSH-minor] Aminopterin / chemistry. Aminopterin / pharmacology. Cell Line, Tumor. Cell Survival / drug effects. Child. Dose-Response Relationship, Drug. Glutamates / chemistry. Glutamates / pharmacology. Guanine / analogs & derivatives. Guanine / chemistry. Guanine / pharmacology. Humans. Inhibitory Concentration 50. Jurkat Cells. Leukemia / pathology. Lymphoma / pathology. Methotrexate / chemistry. Methotrexate / pharmacology. Molecular Structure. Ornithine / analogs & derivatives. Ornithine / chemistry. Ornithine / pharmacology. Pemetrexed. Pterins / chemistry. Pterins / pharmacology

  • COS Scholar Universe. author profiles.
  • Pharmacogenomics Knowledge Base. meta-databases - Pharmacogenomic Annotation 827856814 for PMID:19784838 [PharmGKB] .
  • Hazardous Substances Data Bank. PEMETREXED .
  • Hazardous Substances Data Bank. AMINOPTERIN .
  • Hazardous Substances Data Bank. METHOTREXATE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19784838.001).
  • [ISSN] 1432-0843
  • [Journal-full-title] Cancer chemotherapy and pharmacology
  • [ISO-abbreviation] Cancer Chemother. Pharmacol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / T32-CA09615
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Folic Acid Antagonists; 0 / Glutamates; 0 / Pterins; 04Q9AIZ7NO / Pemetrexed; 113857-87-7 / N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine; 5Z93L87A1R / Guanine; E524N2IXA3 / Ornithine; JYB41CTM2Q / Aminopterin; YL5FZ2Y5U1 / Methotrexate
  •  go-up   go-down


98. Avellino R, Romano S, Parasole R, Bisogni R, Lamberti A, Poggi V, Venuta S, Romano MF: Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells. Blood; 2005 Aug 15;106(4):1400-6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells.
  • The phosphatidyl-inositol 3 kinase (PI3k)/Akt pathway has been implicated in childhood acute lymphoblastic leukemia (ALL).
  • Using a short interfering (si) RNA approach, we demonstrate that FKBP51, a large immunophilin inhibited by rapamycin, is essential for drug-induced NF-kappaB activation in human leukemia.
  • In conclusion, rapamycin targets 2 pathways that are crucial for cell survival and chemoresistance of malignant lymphoblasts--PI3k/Akt through the mammalian target of rapamycin and NF-kappaB through FKBP51--suggesting that the drug could be beneficial in the treatment of childhood ALL.
  • [MeSH-major] Apoptosis / drug effects. Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology. Signal Transduction. Sirolimus / pharmacology
  • [MeSH-minor] Adolescent. Blast Crisis / drug therapy. Blast Crisis / pathology. Bone Marrow Cells / drug effects. Bone Marrow Cells / pathology. Child. Child, Preschool. Doxorubicin / pharmacology. Drug Synergism. Female. Humans. Infant. Male. NF-kappa B / metabolism. Phosphatidylinositol 3-Kinases / metabolism. Protein-Serine-Threonine Kinases / metabolism. Proto-Oncogene Proteins / metabolism. Proto-Oncogene Proteins c-akt. Tacrolimus Binding Proteins / metabolism. Tumor Cells, Cultured


99. Lowas SR, Marks D, Malempati S: Prevalence of transient hyperglycemia during induction chemotherapy for pediatric acute lymphoblastic leukemia. Pediatr Blood Cancer; 2009 Jul;52(7):814-8
Hazardous Substances Data Bank. PREDNISONE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prevalence of transient hyperglycemia during induction chemotherapy for pediatric acute lymphoblastic leukemia.
  • BACKGROUND: Transient hyperglycemia (TH) is a recognized side effect of the corticosteroids and asparaginase given during induction chemotherapy for pediatric acute lymphoblastic leukemia (ALL).
  • This study examined the prevalence of TH in a cohort of pediatric ALL patients and the impact on TH of type of steroid or asparaginase used and of risk factors such as age, gender, and overweight.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Hyperglycemia / chemically induced. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • [MeSH-minor] Adolescent. Asparaginase / administration & dosage. Body Mass Index. Child. Child, Preschool. Cohort Studies. Dexamethasone / administration & dosage. Female. Humans. Male. Polyethylene Glycols / administration & dosage. Prednisone / administration & dosage. Prevalence. Remission Induction. Retrospective Studies. Risk Factors

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • MedlinePlus Health Information. consumer health - Hyperglycemia.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • Hazardous Substances Data Bank. DEXAMETHASONE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19260096.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / pegaspargase; 30IQX730WE / Polyethylene Glycols; 7S5I7G3JQL / Dexamethasone; EC 3.5.1.1 / Asparaginase; VB0R961HZT / Prednisone
  •  go-up   go-down


100. Zevallos JP, Vrabec JT, Williamson RA, Giannoni C, Larrier D, Sulek M, Friedman EM, Oghalai JS: Advanced pediatric mastoiditis with and without intracranial complications. Laryngoscope; 2009 Aug;119(8):1610-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Advanced pediatric mastoiditis with and without intracranial complications.
  • OBJECTIVES/HYPOTHESIS: Recently, several groups have noticed an increase in cases of advanced pediatric mastoiditis and intracranial complications.
  • The objective of this study was to review the bacteriology of advanced mastoiditis in pediatric patients, with the hypothesis that a difference in bacteriology might explain the development of an intracranial complication.
  • METHODS: All pediatric patients with coalescent mastoiditis requiring surgery treated at a tertiary care children's hospital between 2002 and 2007 were reviewed.
  • RESULTS: One hundred eight pediatric patients with coalescent mastoiditis were identified: 58 (53%) presented with coalescent mastoiditis alone, 17 (16%) presented with coalescent mastoiditis and an intracranial complication, and 33 (31%) were excluded because they were treated with myringotomy and tubes alone, had incomplete data, or had an unclear diagnosis.
  • CONCLUSIONS: Nearly a quarter of pediatric patients with coalescent mastoiditis presented with a simultaneous intracranial complication.
  • This series demonstrates the role of aggressive surgical management and close collaboration with the infectious disease service for long-term intravenous antibiotic therapy in treating pediatric patients with advanced mastoiditis.
  • [MeSH-minor] Anti-Bacterial Agents / therapeutic use. Child. Child, Preschool. Cohort Studies. Combined Modality Therapy. Drainage / methods. Female. Follow-Up Studies. Gram-Negative Bacterial Infections / diagnosis. Gram-Negative Bacterial Infections / drug therapy. Gram-Negative Bacterial Infections / epidemiology. Gram-Positive Bacterial Infections / diagnosis. Gram-Positive Bacterial Infections / drug therapy. Gram-Positive Bacterial Infections / epidemiology. Humans. Incidence. Magnetic Resonance Imaging. Male. Mastoid / surgery. Microbial Sensitivity Tests. Otoscopy / methods. Probability. Reference Values. Retrospective Studies. Risk Assessment. Severity of Illness Index. Tomography, X-Ray Computed. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Laryngoscope. 2010 Jul;120(7):1493; author reply 1494 [20583235.001]
  • (PMID = 19504555.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
  •  go-up   go-down






Advertisement