[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 55 of about 55
13. Verstovsek S, Tefferi A, Cortes J, O'Brien S, Garcia-Manero G, Pardanani A, Akin C, Faderl S, Manshouri T, Thomas D, Kantarjian H: Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosis. Clin Cancer Res; 2008 Jun 15;14(12):3906-15
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosis.
  • Only two patients, one with SM-myelofibrosis and one with SM-chronic eosinophilic leukemia, achieved complete response (elimination of mastocytosis) lasting for 5 and 16 months, respectively.
  • Complete responses were achieved in two other patients (acute myeloid leukemia and hypereosinophilic syndrome).
  • CONCLUSION: These data show that dasatinib therapy may benefit a selected group of SM patients, primarily by improving their symptoms, but it does not eliminate the disease in the patients with KIT-D816V mutation.
  • [MeSH-major] Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy. Leukemia, Myeloid, Acute / drug therapy. Mastocytosis, Systemic / drug therapy. Pyrimidines / therapeutic use. Thiazoles / therapeutic use


1
Advertisement
4. Nishioka C, Ikezoe T, Yang J, Yokoyama A: Long-term exposure of leukemia cells to multi-targeted tyrosine kinase inhibitor induces activations of AKT, ERK and STAT5 signaling via epigenetic silencing of the PTEN gene. Leukemia; 2010 Sep;24(9):1631-40
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term exposure of leukemia cells to multi-targeted tyrosine kinase inhibitor induces activations of AKT, ERK and STAT5 signaling via epigenetic silencing of the PTEN gene.
  • Imatinib induces complete molecular response in patients with chronic myeloid leukemia (CML) and chronic eosinophilic leukemia (CEL).
  • Notably, hypermethylation of the promoter region of the PTEN gene in association with the downregulation of this gene's transcripts was identified in imatinib-resistant leukemia cells isolated from individuals with CEL, CML and Philadelphia-positive acute lymphoblastic leukemia.
  • Taken together, epigenetic silence of PTEN is one of the mechanisms that cause drug resistance in individuals with leukemia after exposure to imatinib.
  • [MeSH-major] Epigenesis, Genetic. Extracellular Signal-Regulated MAP Kinases / metabolism. Gene Silencing. Hypereosinophilic Syndrome / pathology. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology. PTEN Phosphohydrolase / genetics. Protein Kinase Inhibitors / pharmacology. Proto-Oncogene Proteins c-akt / metabolism. STAT5 Transcription Factor / metabolism. Signal Transduction


15. Chu KH, Lee CC, Hsin SC, Cai BC, Wang JH, Chiang BL: Arsenic trioxide alleviates airway hyperresponsiveness and eosinophilia in a murine model of asthma. Cell Mol Immunol; 2010 Sep;7(5):375-80
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The clinical hallmarks of asthma include elevated serum levels of immunoglobulin E (IgE), eosinophilic inflammation and airway hyper-responsiveness (AHR).
  • Today, As2O3 is used as one of the standard therapies for acute promyelocytic leukemia (APL).
  • [MeSH-minor] Animals. Apoptosis / drug effects. Bronchoalveolar Lavage Fluid / immunology. Cells, Cultured. Disease Models, Animal. Female. Immunoglobulin E / blood. Interleukin-5 / immunology. Mice. Mice, Inbred BALB C

  • MedlinePlus Health Information. consumer health - Asthma.
  • Hazardous Substances Data Bank. ARSENIC TRIOXIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cytokine. 2002 Jul 21;19(2):76-84 [12182842.001]
  • [Cites] Cancer Treat Rev. 2007 Oct;33(6):542-64 [17624680.001]
  • [Cites] Allergy. 2003 Nov;58(11):1117-24 [14616121.001]
  • [Cites] Toxicol Sci. 2004 Jun;79(2):248-57 [15056798.001]
  • [Cites] Gene Ther. 2004 Oct;11(20):1497-505 [15269717.001]
  • [Cites] J Soc Occup Med. 1978 Jan;28(1):3-5 [340784.001]
  • [Cites] Am Rev Respir Dis. 1990 Dec;142(6 Pt 1):1407-13 [2252260.001]
  • [Cites] N Engl J Med. 1992 Jan 30;326(5):298-304 [1530827.001]
  • [Cites] Adv Immunol. 1992;51:323-82 [1502977.001]
  • [Cites] J Clin Invest. 1993 Mar;91(3):1176-82 [8450046.001]
  • [Cites] J Exp Med. 1994 Mar 1;179(3):881-7 [7509365.001]
  • [Cites] Mutat Res. 1994 Apr;312(2):111-20 [7510822.001]
  • [Cites] J Exp Med. 1996 Oct 1;184(4):1461-9 [8879217.001]
  • [Cites] Blood. 1997 May 1;89(9):3345-53 [9129041.001]
  • [Cites] J Exp Med. 1997 Aug 18;186(4):601-12 [9254658.001]
  • [Cites] Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1):766-75 [9309991.001]
  • [Cites] J Immunol. 1997 Nov 1;159(9):4593-601 [9379061.001]
  • [Cites] J Natl Cancer Inst. 1998 Jan 21;90(2):124-33 [9450572.001]
  • [Cites] Eur J Immunol. 1997 Dec;27(12):3507-16 [9464841.001]
  • [Cites] Blood. 1998 Apr 1;91(7):2240-8 [9516121.001]
  • [Cites] N Engl J Med. 1998 May 28;338(22):1592-600 [9603798.001]
  • [Cites] N Engl J Med. 1998 Nov 5;339(19):1341-8 [9801394.001]
  • [Cites] Scand J Immunol. 1999 Mar;49(3):229-36 [10102639.001]
  • [Cites] Acta Derm Venereol Suppl (Stockh). 1950 Sep 4-10;31(Suppl. 24):44-8 [14829189.001]
  • [Cites] Trends Mol Med. 2005 Apr;11(4):148-52 [15823751.001]
  • [Cites] Respir Res. 2006;7:146 [17178007.001]
  • [Cites] Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Apr;22(4):292-4 [12584795.001]
  • (PMID = 20495578.001).
  • [ISSN] 2042-0226
  • [Journal-full-title] Cellular & molecular immunology
  • [ISO-abbreviation] Cell. Mol. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Arsenicals; 0 / Interleukin-5; 0 / Oxides; 37341-29-0 / Immunoglobulin E; S7V92P67HO / arsenic trioxide
  • [Other-IDs] NLM/ PMC4002675
  •  go-up   go-down


28. Doki N, Hoshino T, Irisawa H, Sakura T, Miyawaki S: [Acute myeloid leukemia complicated with pulmonary alveolar proteinosis at presentation]. Rinsho Ketsueki; 2005 Jul;46(7):522-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Acute myeloid leukemia complicated with pulmonary alveolar proteinosis at presentation].
  • Following the results obtained from a bone marrow aspiration, he was diagnosed as having acute myeloid leukemia (AML).
  • Although the autopsy findings revealed no infectious lesions in his lungs, a PAS-positive intra-alveolar eosinophilic material, which was positive for surfactant apoprotein A staining, was present.
  • As a result of the autopsy findings, a diagnosis of secondary pulmonary alveolar proteinosis (PAP) associated with AML was made.
  • [MeSH-major] Leukemia, Myeloid, Acute / complications. Pulmonary Alveolar Proteinosis / etiology

  • Genetic Alliance. consumer health - Leukemia, Myeloid.
  • MedlinePlus Health Information. consumer health - Acute Myeloid Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16440746.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


29. Wakabayashi S, Yamamoto K, Arai A, Miura O: [Chronic eosinophilic leukemia with complex karyotypic abnormalities including trisomy 8]. Rinsho Ketsueki; 2008 Jul;49(7):510-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Chronic eosinophilic leukemia with complex karyotypic abnormalities including trisomy 8].
  • We report a 61-year-old man with chronic eosinophilic leukemia (CEL).
  • Although he had no obvious organ damage at diagnosis, pulmonary infiltrates in the right lung and multiple skin nodules over his whole body appeared over 4 months and progressed rapidly, accompanied by a marked increase in blasts in his peripheral blood.
  • CEL with trisomy 8 has been reported to be associated with transformation into acute leukemia and granulocytic sarcoma in the literature.
  • It is notable that the present case was associated with complex karyotypic abnormalities and the exceptionally marked disease progression.
  • Further analyses of clinical data as well as molecular genetic findings of CEL without known karyotypic abnormalities leading to constitutive activation of tyrosine-kinase genes are needed to gain insight into the pathogenesis of CEL and to develop a new disease classification and treatment strategies.
  • [MeSH-minor] Chronic Disease. Humans. Karyotyping. Male. Middle Aged

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18709984.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


30. Tefferi A, Elliott MA, Pardanani A: Atypical myeloproliferative disorders: diagnosis and management. Mayo Clin Proc; 2006 Apr;81(4):553-63
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical myeloproliferative disorders: diagnosis and management.
  • The World Health Organization system for classification of tumors of the hematopoietic system divides myeloid disorders into acute myeloid leukemia and chronic myeloid disorders based on the presence or absence, respectively, of acute myeloid leukemia--defining morphological and cytogenetic features including the presence of 20% or more myeloblasts in either the bone marrow or the peripheral blood.
  • Classic MPD includes polycythemia vera, essential thrombocythemia, myelofibrosis with myeloid metaplasia, and chronic myeloid leukemia.
  • The current review focuses on the diagnosis and treatment of both molecularly defined and clinicopathologically assigned categories of atypical MPD: chronic myelomonocytic leukemia, juvenile myelomonocytic leukemia, chronic neutrophilic leukemia, chronic basophilic leukemia, chronic eosinophilic leukemia, idiopathic eosinophilia including hypereosinophilic syndrome, systemic mastocytosis, unclassified MPD, and eosinophilic/mast cell disorders associated with mutations of platelet-derived growth factor receptors alpha (PDGFRA) and beta (PDGFRB), FGFR1, and KIT.
  • [MeSH-minor] Biomarkers, Tumor / genetics. Bone Marrow / pathology. Diagnosis, Differential. Humans

  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16610578.001).
  • [ISSN] 0025-6196
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 173
  •  go-up   go-down


31. Cools J: Identification and characterization of novel oncogenes in chronic eosinophilic leukemia and T-cell acute lymphoblastic leukemia. Verh K Acad Geneeskd Belg; 2010;72(1-2):55-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification and characterization of novel oncogenes in chronic eosinophilic leukemia and T-cell acute lymphoblastic leukemia.
  • Insights into these mechanisms may help us to design novel strategies to treat leukemia.
  • Sorafenib was originally developed as a BRAF inhibitor, but our work demonstrates that sorafenib can also be used to treat FIP1L1-PDGFRA positive leukemia, demonstrating that new therapies to treat rare leukemias may be simply found by testing drugs that are already in use for the treatment of other diseases.
  • [MeSH-major] Hypereosinophilic Syndrome / genetics. Nuclear Pore Complex Proteins / genetics. Oncogene Proteins, Fusion / genetics. Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics. Receptor, Platelet-Derived Growth Factor alpha / genetics. mRNA Cleavage and Polyadenylation Factors / genetics

  • Genetic Alliance. consumer health - Acute Lymphoblastic Leukemia.
  • Genetic Alliance. consumer health - Leukemia, T-cell, chronic.
  • Hazardous Substances Data Bank. NICOTINAMIDE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20726440.001).
  • [ISSN] 0302-6469
  • [Journal-full-title] Verhandelingen - Koninklijke Academie voor Geneeskunde van België
  • [ISO-abbreviation] Verh. K. Acad. Geneeskd. Belg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Belgium
  • [Chemical-registry-number] 0 / Benzenesulfonates; 0 / FIP1L1-PDGFRA fusion protein, human; 0 / NUP214 protein, human; 0 / Nuclear Pore Complex Proteins; 0 / Oncogene Proteins; 0 / Oncogene Proteins, Fusion; 0 / Phenylurea Compounds; 0 / Protein Kinase Inhibitors; 0 / Pyridines; 0 / mRNA Cleavage and Polyadenylation Factors; 25X51I8RD4 / Niacinamide; 9ZOQ3TZI87 / sorafenib; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha
  •  go-up   go-down


32. O'Shea AM, Wilson GJ, Ling SC, Minassian BA, Turnbull J, Cutz E: Lafora-like ground-glass inclusions in hepatocytes of pediatric patients: a report of two cases. Pediatr Dev Pathol; 2007 Sep-Oct;10(5):351-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Case 1 had alpha-thalassaemia major and was receiving iron chelation therapy, whereas case 2 had trisomy 21 with a history of bone marrow transplantation for acute myeloid leukemia.
  • The liver sections in both cases showed eosinophilic, periodic acid-Schiff diastase-positive intracytoplasmic inclusions that were negative for hepatitis B surface antigen.
  • Ultrastructural changes in both cases differed from classical Lafora inclusions and ruled out hepatitis B surface antigen, glycogenosis type IV, and fibrinogen storage disease.
  • Genetic analysis of the Lafora's disease genes performed in case 2 revealed no mutations.
  • Drug-induced inclusions, mimicking Lafora's disease, should be included in the differential diagnosis of hepatocyte ground-glass inclusions.
  • [MeSH-minor] Anti-Bacterial Agents / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Bone Marrow Transplantation. Child, Preschool. Diagnosis, Differential. Down Syndrome. Humans. Immunohistochemistry. Iron. Lafora Disease / pathology. Leukemia, Myeloid, Acute / therapy. Male. Microscopy, Electron, Transmission. alpha-Thalassemia / drug therapy

  • Hazardous Substances Data Bank. DESFERRIOXAMINE .
  • Hazardous Substances Data Bank. IRON, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17929993.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; E1UOL152H7 / Iron; J06Y7MXW4D / Deferoxamine
  •  go-up   go-down


33. Kamineni P, Baptiste A, Hassan M, Dawkins FW, Zaidi S, Tefferi A, Lindsey M, Taddesse-Heath L: Case of chronic eosinophilic leukemia with deletion of chromosome 16 and hepatitis C. J Natl Med Assoc; 2006 Aug;98(8):1356-60
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case of chronic eosinophilic leukemia with deletion of chromosome 16 and hepatitis C.
  • Chronic eosinophilic leukemia is a rare entity, characterized by eosinophilia of >1.5 x 10(9)/L, persisting for >6 months after exclusion of other reactive and neoplastic causes of eosinophilia, and occurring in association with a clonal cytogenetic abnormality.
  • Various chromosomal abnormalities have been associated with chronic eosinophilic leukemia.
  • Partial deletion of the long arm of chromosome 16 is a cytogenetic abnormality first reported 20 years ago in patients with acute myeloid leukemia associated with bone marrow eosinophilia (AML-M4Eo).
  • To our knowledge, this is the first case report of isolated del (16) (q22), a cytogenetic abnormality associated with AML-M4Eo, occurring in chronic eosinophilic leukemia.
  • [MeSH-minor] Biopsy. Bone Marrow / pathology. Chronic Disease. Diagnosis, Differential. Humans. Male. Middle Aged

  • Genetic Alliance. consumer health - Chromosome 16.
  • Genetic Alliance. consumer health - Hepatitis.
  • MedlinePlus Health Information. consumer health - Hepatitis C.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] N Engl J Med. 2003 Mar 27;348(13):1201-14 [12660384.001]
  • [Cites] Metab Brain Dis. 2004 Dec;19(3-4):357-81 [15554428.001]
  • [Cites] Br J Haematol. 2003 Jul;122(2):173-9 [12846884.001]
  • [Cites] Blood. 2003 Aug 1;102(3):996-9 [12714514.001]
  • [Cites] Int J Cancer. 2004 Jun 20;110(3):380-5 [15095303.001]
  • [Cites] Medicine (Baltimore). 1975 Jan;54(1):1-27 [1090795.001]
  • [Cites] J Clin Pathol. 1975 Dec;28(12):956-61 [1206119.001]
  • [Cites] Blood. 1981 Nov;58(5):1021-6 [7197566.001]
  • [Cites] Blood. 1983 May;61(5):994-8 [6831056.001]
  • [Cites] Q J Med. 1983 Winter;52(205):1-22 [6878618.001]
  • [Cites] Cancer Genet Cytogenet. 1984 Apr;11(4):389-4 [6704940.001]
  • [Cites] Cancer Genet Cytogenet. 1986 Apr 15;21(4):327-33 [3955530.001]
  • [Cites] Br J Dermatol. 1995 May;132(5):821-3 [7772493.001]
  • [Cites] Leukemia. 1995 Jun;9(6):965-71 [7596186.001]
  • [Cites] Br J Haematol. 1997 Jan;96(1):117-23 [9012697.001]
  • [Cites] Leukemia. 1997 Apr;11 Suppl 3:516-8 [9209442.001]
  • [Cites] Ann Intern Med. 1997 Sep 15;127(6):423-8 [9312998.001]
  • [Cites] Eur J Gastroenterol Hepatol. 1997 Sep;9(9):909-11 [9355792.001]
  • [Cites] Cancer Genet Cytogenet. 1998 Dec;107(2):111-7 [9844604.001]
  • [Cites] Am J Hematol. 1999 Mar;60(3):229-30 [10072116.001]
  • [Cites] Blood. 2003 May 1;101(9):3391-7 [12506022.001]
  • (PMID = 16916138.001).
  • [ISSN] 1943-4693
  • [Journal-full-title] Journal of the National Medical Association
  • [ISO-abbreviation] J Natl Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2569582
  •  go-up   go-down


34. Khémiri M, Ouederni M, Ben Mansour F, Ben Jaballah N, Barsaoui S: [Acute respiratory failure revealing an idiopathic acute eosinophilic pneumonia: report of a pediatric case]. Ann Fr Anesth Reanim; 2008 Jun;27(6):502-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Acute respiratory failure revealing an idiopathic acute eosinophilic pneumonia: report of a pediatric case].
  • [Transliterated title] Insuffisance respiratoire aiguë révélant un poumon aigu éosinophile idiopathique: à propos d'une observation pédiatrique.
  • Eosinophilic pneumonias are a group of heterogeneous disorders, rarely reported in children.
  • We describe a case of a 12-year-old boy hospitalized for an acute febrile respiratory failure.
  • A pulmonary eosinophilic infiltration was confirmed by a major blood eosinophilia at 33,800/mm(3) associated with increased eosinophilic rate (90%) on bronchoalveolar lavage fluid.
  • Laboratory screenings for parasitic or allergic disease were negative.
  • Bone marrow smear and medullar caryotype eliminated an acute leukemia.
  • No further visceral eosinophilic injury were found.
  • Acute eosinophilic pneumonia should be included in etiological investigation of patients with acute respiratory distress syndrome (ARDS) even in young subjects.
  • [MeSH-major] Pulmonary Eosinophilia / diagnosis. Respiratory Insufficiency / etiology
  • [MeSH-minor] Child. Humans. Male. Radiography, Thoracic. Respiration, Artificial. Respiratory Distress Syndrome, Adult / diagnosis. Respiratory Distress Syndrome, Adult / therapy. Treatment Outcome


35. Ma Y, Tong HX, Deng X, Zhao Y, Liu ZG, Zhang JH: [MICM characteristics and typing diagnosis in acute myelogenous leukemia patients (AML-M2) with complex karyotype t (2;21;8)(p12;q22;q22)]. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2009 Feb;17(1):12-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [MICM characteristics and typing diagnosis in acute myelogenous leukemia patients (AML-M2) with complex karyotype t (2;21;8)(p12;q22;q22)].
  • This study was purposed to investigate the acute myeloid leukemia with complex karyotype t(2;21;8)(p12;q22;q22) (AML-M(2)) by using morphologic, immunologic, cytogenetic and molecular biologic classification technique (MICM) and to analyze the MICM characteristics of AML-M(2) and their diagnostic significance.
  • The results indicated that the bone marrow smears of case 1 showed extremely hyperplasia with myeloblasts in which a ratio of eosinophilic granulocytes and monocytes increased.

  • Genetic Alliance. consumer health - Acute Myeloid Leukemia, Adult.
  • MedlinePlus Health Information. consumer health - Acute Myeloid Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19236738.001).
  • [ISSN] 1009-2137
  • [Journal-full-title] Zhongguo shi yan xue ye xue za zhi
  • [ISO-abbreviation] Zhongguo Shi Yan Xue Ye Xue Za Zhi
  • [Language] CHI
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


36. Yoshimi M, Nannya Y, Watanabe T, Asai T, Ichikawa M, Yamamoto G, Kumano K, Hangaishi A, Imai Y, Takahashi T, Chiba S, Kurokawa M: Acute eosinophilic pneumonia is a non-infectious lung complication after allogeneic hematopoietic stem cell transplantation. Int J Hematol; 2009 Mar;89(2):244-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acute eosinophilic pneumonia is a non-infectious lung complication after allogeneic hematopoietic stem cell transplantation.
  • Acute eosinophilic pneumonia (AEP) is an acute febrile illness with respiratory impairment, diffuse pulmonary infiltrates, and eosinophilia in bronchoalveolar lavage (BAL) fluid.
  • We made a diagnosis of AEP and steroid was started.
  • [MeSH-minor] Graft vs Host Disease / pathology. Humans. Leukemia / complications. Leukemia / therapy. Male. Middle Aged. Pneumonia. Transplantation, Homologous

  • Genetic Alliance. consumer health - Pneumonia, eosinophilic.
  • Genetic Alliance. consumer health - Transplantation.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Respir Crit Care Med. 2002 Nov 1;166(9):1235-9 [12403693.001]
  • [Cites] Diagn Microbiol Infect Dis. 2005 Aug;52(4):275-80 [15936168.001]
  • [Cites] Radiology. 1998 Jun;207(3):829-31 [9609914.001]
  • [Cites] Exp Hematol. 2008 Aug;36(8):988-96 [18410989.001]
  • [Cites] Blood. 2003 Dec 1;102(12):4236-42 [12907447.001]
  • [Cites] Allergy. 2004 Aug;59(8):850-6 [15230818.001]
  • [Cites] Ann Allergy Asthma Immunol. 1996 May;76(5):419-22 [8630714.001]
  • [Cites] Biol Blood Marrow Transplant. 2006 Oct;12(10):1038-46 [17067910.001]
  • [Cites] Transplantation. 1997 Apr 27;63(8):1079-86 [9133468.001]
  • [Cites] Ann Hematol. 2006 Mar;85(3):202-3 [16389562.001]
  • [Cites] Br J Haematol. 1995 Aug;90(4):963-5 [7669682.001]
  • [Cites] Nihon Kyobu Shikkan Gakkai Zasshi. 1993 Dec;31(12):1578-84 [8121096.001]
  • [Cites] Bone Marrow Transplant. 2001 May;27(9):893-8 [11436099.001]
  • [Cites] Clin Chest Med. 1990 Jun;11(2):323-32 [2189666.001]
  • [Cites] Clin Chest Med. 2004 Mar;25(1):189-201 [15062610.001]
  • [Cites] Medicine (Baltimore). 1996 Nov;75(6):334-42 [8982150.001]
  • [Cites] Int J Hematol. 2000 Jul;72(1):92-7 [10979216.001]
  • [Cites] Rev Mal Respir. 2008 Feb;25(2):173-83 [18449079.001]
  • [Cites] Radiol Clin North Am. 1996 Jan;34(1):97-117 [8539356.001]
  • [Cites] Am Rev Respir Dis. 1989 Jan;139(1):249-52 [2912347.001]
  • [Cites] Chest. 1991 Sep;100(3):875-7 [1889295.001]
  • [Cites] Intern Med. 2000 Oct;39(10 ):830-3 [11030209.001]
  • [Cites] Cancer. 1986 Sep 1;58(5):1047-54 [3524798.001]
  • [Cites] Am J Respir Crit Care Med. 1994 Nov;150(5 Pt 1):1423-38 [7952571.001]
  • [Cites] Hum Pathol. 1992 Oct;23(10):1172-7 [1398645.001]
  • [Cites] Am Rev Respir Dis. 1993 Jun;147(6 Pt 1):1601-6 [8503576.001]
  • [Cites] BMJ. 1993 Jan 9;306(6870):109 [8435603.001]
  • [Cites] J Immunol. 2005 Nov 1;175(9):5732-43 [16237064.001]
  • [Cites] Respiration. 2001;68(4):389-95 [11464086.001]
  • (PMID = 19132457.001).
  • [ISSN] 1865-3774
  • [Journal-full-title] International journal of hematology
  • [ISO-abbreviation] Int. J. Hematol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


37. Gérard J, Berdin B, Portier G, Godon A, Tessier-Marteau A, Geneviève F, Zandecki M: [Bone marrow necrosis in two patients with neoplastic disorders]. Ann Biol Clin (Paris); 2007 Nov-Dec;65(6):636-42
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Diagnosis is done on characteristic cytological pattern of the bone marrow aspiration and/or biopsy.
  • An haematological malignancy was suspected after observation of a few peripheral blood blast cells, but necrosis was found on the bone marrow aspiration and could not lead to further haematological diagnosis.
  • Within next days, the white blood cell count and the number of blasts increased, leading to the diagnosis of acute monoblastic leukaemia.
  • The second patient, aged 28, has been hospitalized for severe bleeding a few days after the diagnosis of a metastatic gastric tumour.
  • According to literature, bone marrow necrosis is in most instances secondary to either an haematological malignancy (60%) or to a solid tumour (30%), but only at times observed with a non-malignant disorder.
  • Bone pain, fever, cytopenias and elevated serum lactic dehydrogenase and alkaline phosphatase are frequently reported, but are mostly non specific of the diagnosis in these malignant conditions.
  • Examination of the bone marrow leads to the diagnosis: cells are pycnotic, scarcely recognizable in a background of amorphous extracellular eosinophilic proteinaceous material, and histology shows disappearance of fat spaces with preservation of the bone tissue.
  • Tissue hypoxemia due to microcirculation failure may be the main mechanism leading to the necrosis, whatever the related disorder.
  • Supportive care together with specific therapy of the causal disease must be started promptly.
  • [MeSH-major] Bone Marrow / pathology. Leukemia, Monocytic, Acute / pathology. Stomach Neoplasms / pathology

  • Genetic Alliance. consumer health - Bone marrow necrosis.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18039608.001).
  • [ISSN] 0003-3898
  • [Journal-full-title] Annales de biologie clinique
  • [ISO-abbreviation] Ann. Biol. Clin. (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


38. Qin Y, Auh S, Blokh L, Long C, Gagnon I, Hamann KJ: TNF-alpha induces transient resistance to Fas-induced apoptosis in eosinophilic acute myeloid leukemia cells. Cell Mol Immunol; 2007 Feb;4(1):43-52
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] TNF-alpha induces transient resistance to Fas-induced apoptosis in eosinophilic acute myeloid leukemia cells.
  • Because TNF-alpha activates NF-kappaB in many cell types including inflammatory cells such as eosinophils, we examined effects of TNF-alpha signaling on the Fas-mediated killing of an eosinophilic cell line AML14.
  • This finding suggested that TNF-alpha may contribute to the prolonged survival of inflammatory cells by suppression of Fas-mediated apoptosis, the process involved with NF-kappaB transactivation, anti-apoptotic XIAP up-regulation and caspase suppression.
  • [MeSH-minor] Acute Disease. Anti-Inflammatory Agents, Non-Steroidal / pharmacology. Antibodies, Monoclonal / pharmacology. Electrophoretic Mobility Shift Assay. Eosinophils / drug effects. Eosinophils / immunology. Fas Ligand Protein / antagonists & inhibitors. Humans. I-kappa B Kinase / antagonists & inhibitors. I-kappa B Kinase / metabolism. Leukemia, Myeloid. Nitriles / pharmacology. Sesquiterpenes / pharmacology. Sulfones / pharmacology. Tumor Cells, Cultured

  • Genetic Alliance. consumer health - Leukemia, Myeloid.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17349210.001).
  • [ISSN] 1672-7681
  • [Journal-full-title] Cellular & molecular immunology
  • [ISO-abbreviation] Cell. Mol. Immunol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL66026; United States / NHLBI NIH HHS / HL / HL79641
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Antibodies, Monoclonal; 0 / BAY 11-7085; 0 / Fas Ligand Protein; 0 / NF-kappa B; 0 / Nitriles; 0 / Sesquiterpenes; 0 / Sulfones; 0 / Tumor Necrosis Factor-alpha; 0 / X-Linked Inhibitor of Apoptosis Protein; 0 / XIAP protein, human; 2RDB26I5ZB / parthenolide; EC 2.7.11.10 / I-kappa B Kinase
  •  go-up   go-down


39. Niedzielska E, Wójcik D, Barg E, Pietras W, Sega-Pondel D, Doroszko A, Niedzielska M, Skarzyńska M, Chybicka A: [Evaluation of selected endocrine complications in patients treated with auto- and allo-haematopoietic stem cell transplantation]. Med Wieku Rozwoj; 2008 Jul-Sep;12(3):761-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIAL AND METHODS: The investigated group consisted of: I. 16 patients after auto-HSCT (6 girls, 10 boys) aged 3-20 years (average 10,8+/-) because of acute myelogenous leukaemia (n=5), non Hodgkin lymphoma (n=3), neuroblastoma (n=3), embryonal cancer (n=2), medulloblastoma (n=1), Ewing's sarcoma/PNET (n=1), hyper eosinophilic syndrome (n=1).
  • Indication for HSCT was acute lymphoblastic leukaemia (n=11), acute myelogenous leukaemia (n=5), chronic myeloid leukaemia-CML (n=6), myelodysplastic syndromes (n=2), non Hodgkin lymphoma (n=1), juvenile myelomonocytic leukemia (n=1), severe aplastic anaemia (n=1), Blackfan-Diamond anaemia (n=1), severe combined immune deficiency (n=1), rhabdomyosarcoma (n=1).
  • [MeSH-major] Endocrine System Diseases / etiology. Hematopoietic Stem Cell Transplantation / adverse effects. Leukemia / therapy


40. Vega F, Medeiros LJ, Davuluri R, Cromwell CC, Alkan S, Abruzzo LV: t(8;13)-positive bilineal lymphomas: report of 6 cases. Am J Surg Pathol; 2008 Jan;32(1):14-20
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Approximately 75% of EMS patients present with or develop precursor T-cell lymphoblastic lymphoma, and most subsequently develop acute myeloid leukemia.
  • Histologically, each tumor was composed of 2 distinct cellular components: small to medium-sized T cells with scant cytoplasm that resembled lymphoblasts, and larger immature-appearing cells with more abundant eosinophilic cytoplasm that resembled myeloblasts, a subset of which expressed myeloid antigens.
  • We believe that these bilineal neoplasms of mixed T-cell and myeloid lineages, which present as lymphoma, are analogous to bilineal leukemias.

  • MedlinePlus Health Information. consumer health - Lymphoma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18162765.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD
  •  go-up   go-down


41. Aissi K, Rossi P, Le TB, Granel B, Bagnères D, Demoux AL, Bonin-Guillaume S, Costello R, Sebahoun G, Francès Y: [Necrotic myocarditis in acute eosinophilic lymphoblastic leukaemia]. Rev Med Interne; 2006 Nov;27(11):869-73
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Necrotic myocarditis in acute eosinophilic lymphoblastic leukaemia].
  • The association between an acute lymphoblastic leukemia and hypereosinophilia was rare.
  • We report a case of a 29-year-old man who presented a heart failure secondary to necrotic myocarditis related to an acute eosinophilic lymphoblastic leukaemia.
  • The myelogram cytology showed precursor B-cell acute lymphoblastic leukaemia with hypereosinophilia.


42. Tasaka T, Matsuhashi Y, Ohnishi H, Kubota Y: Eosinophilic cystitis following cord blood transplantation: a form of acute GVHD. A variant of hemorrhagic cystitis after hematopoietic SCT or drug-induced? Bone Marrow Transplant; 2008 Oct;42(7):495-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eosinophilic cystitis following cord blood transplantation: a form of acute GVHD. A variant of hemorrhagic cystitis after hematopoietic SCT or drug-induced?
  • [MeSH-major] Cord Blood Stem Cell Transplantation / adverse effects. Cystitis / etiology. Graft vs Host Disease / diagnosis. Hematopoietic Stem Cell Transplantation / adverse effects. Hemorrhage / etiology. Leukemia, Myelomonocytic, Acute / surgery


43. Walz C, Curtis C, Schnittger S, Schultheis B, Metzgeroth G, Schoch C, Lengfelder E, Erben P, Müller MC, Haferlach T, Hochhaus A, Hehlmann R, Cross NC, Reiter A: Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene. Genes Chromosomes Cancer; 2006 Oct;45(10):950-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene.
  • Here we report a female patient who presented with advanced phase of a chronic eosinophilic leukemia.
  • Despite achieving complete cytogenetic and molecular remission on imatinib, the patient relapsed with imatinib-resistant acute myeloid leukemia that was characterized by a normal karyotype, absence of detectable CDK5RAP2-PDGFRA mRNA, and a newly acquired G12D NRAS mutation.
  • [MeSH-minor] Aged. Amino Acid Sequence. Base Sequence. Benzamides. Chronic Disease. DNA Mutational Analysis. Female. Gene Expression Regulation, Neoplastic / drug effects. Humans. Imatinib Mesylate. In Situ Hybridization, Fluorescence. Intracellular Signaling Peptides and Proteins / genetics. Molecular Sequence Data. Nerve Tissue Proteins / genetics. Protein-Tyrosine Kinases / antagonists & inhibitors. Receptor, Platelet-Derived Growth Factor alpha / antagonists & inhibitors. Receptor, Platelet-Derived Growth Factor alpha / genetics. Reverse Transcriptase Polymerase Chain Reaction

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. IMATINIB MESYLATE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16845659.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzamides; 0 / CDK5RAP2 protein, human; 0 / Intracellular Signaling Peptides and Proteins; 0 / Nerve Tissue Proteins; 0 / Oncogene Proteins, Fusion; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha
  •  go-up   go-down


44. Tefferi A, Gilliland G: Classification of chronic myeloid disorders: from Dameshek towards a semi-molecular system. Best Pract Res Clin Haematol; 2006;19(3):365-85
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In turn, myeloid malignancies are broadly categorized into either acute myeloid leukemia (AML) or chronic myeloid disorder (CMD), depending on the presence or absence, respectively, of AML-defining cytomorphologic and cytogenetic features.
  • It has now become evident that most CMD represent clonal stem cell processes where the primary oncogenic event has been characterized in certain instances; Bcr/Abl in chronic myeloid leukemia, FIP1L1-PDGFRA or c-kit(D816V) in systemic mastocytosis, rearrangements of PDGFRB in chronic eosinophilic leukemia, and rearrangements of FGFR1 in stem cell leukemia/lymphoma syndrome.
  • In addition, Bcr/Abl-negative classic myeloproliferative disorders are characterized by recurrent JAK2(V617F) mutations, whereas other mutations affecting the RAS signaling pathway molecules have been associated with juvenile myelomonocytic leukemia.
  • [MeSH-minor] Fusion Proteins, bcr-abl / genetics. Genes, abl. Humans. Janus Kinase 2. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / classification. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics. Myelodysplastic Syndromes / classification. Myelodysplastic Syndromes / genetics. Protein-Tyrosine Kinases / genetics. Proto-Oncogene Proteins / genetics. Receptor, Platelet-Derived Growth Factor beta / genetics

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16781478.001).
  • [ISSN] 1521-6926
  • [Journal-full-title] Best practice & research. Clinical haematology
  • [ISO-abbreviation] Best Pract Res Clin Haematol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor beta; EC 2.7.10.2 / Fusion Proteins, bcr-abl; EC 2.7.10.2 / JAK2 protein, human; EC 2.7.10.2 / Janus Kinase 2
  • [Number-of-references] 232
  •  go-up   go-down


45. Metzelder SK, Reinke C, Walthers EM, Barth P, Vogelmeier C, Neubauer A, Bals R: ["Malignant" ARDS]. Internist (Berl); 2009 Oct;50(10):1272, 1274-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acute respiratory failure and the "acute respiratory distress syndrome" (ARDS) are frequent medical conditions in critically ill patients.
  • The first patient was diagnosed with an acute myeloic leukemia M5 (FAB).
  • These case reports show that in addition to the classical causes of ARDS, specific disease entities can mimic this form of respiratory failure.
  • Beside solid cancers and lymphomas, acute and progressive forms of inflammatory, parenchymal lung diseases (such as acute interstitial pneumonitis, acute eosinophilic pneumonia, diffuse alveolar hemorrhagia, and acute hypersensitivity pneumonitis) can manifest with this picture.
  • [MeSH-major] Adenocarcinoma / complications. Adenocarcinoma / diagnosis. Lung Diseases, Interstitial / complications. Lung Diseases, Interstitial / diagnosis. Lung Neoplasms / complications. Lung Neoplasms / diagnosis. Respiratory Distress Syndrome, Adult / diagnosis. Respiratory Distress Syndrome, Adult / etiology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Middle Aged

  • MedlinePlus Health Information. consumer health - Interstitial Lung Diseases.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Crit Care. 1994 Mar;9(1):72-81 [8199655.001]
  • [Cites] Genes Chromosomes Cancer. 2000 Aug;28(4):415-24 [10862050.001]
  • [Cites] Chest. 2004 Apr;125(4):1530-5 [15078770.001]
  • [Cites] Thorax. 2002 May;57(5):452-8 [11978926.001]
  • [Cites] Am J Respir Crit Care Med. 2002 Jan 15;165(2):277-304 [11790668.001]
  • (PMID = 19562262.001).
  • [ISSN] 1432-1289
  • [Journal-full-title] Der Internist
  • [ISO-abbreviation] Internist (Berl)
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


46. Roufosse F, Goldman M, Cogan E: Hypereosinophilic syndrome: lymphoproliferative and myeloproliferative variants. Semin Respir Crit Care Med; 2006 Apr;27(2):158-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Idiopathic hypereosinophilic syndrome is a largely heterogeneous disorder defined as persistent, marked hypereosinophilia of unknown origin complicated by end-organ damage.
  • As far as prognosis of these disease variants is concerned, hypereosinophilic syndrome patients with the FIP1L1-PDGFRalpha fusion gene may develop acute myelogenous (eosinophilic) leukemia, whereas those with clonal interleukin-5-producing T-cells have an increased risk of developing T-cell lymphoma.
  • [MeSH-major] Hypereosinophilic Syndrome / classification. Hypereosinophilic Syndrome / diagnosis. Lymphoproliferative Disorders / diagnosis. Myeloproliferative Disorders / diagnosis

  • Genetic Alliance. consumer health - Hypereosinophilic syndromes.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. IMATINIB MESYLATE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16612767.001).
  • [ISSN] 1069-3424
  • [Journal-full-title] Seminars in respiratory and critical care medicine
  • [ISO-abbreviation] Semin Respir Crit Care Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, CD; 0 / Antigens, Neoplasm; 0 / Antineoplastic Agents; 0 / Benzamides; 0 / CD52 antigen; 0 / FIP1L1-PDGFRA fusion protein, human; 0 / Glucocorticoids; 0 / Glycoproteins; 0 / Immunologic Factors; 0 / Interleukin-5; 0 / Oncogene Proteins, Fusion; 0 / Piperazines; 0 / Pyrimidines; 0 / mRNA Cleavage and Polyadenylation Factors; 8A1O1M485B / Imatinib Mesylate; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha
  • [Number-of-references] 70
  •  go-up   go-down


47. González-Vela MC, Val-Bernal JF, Mayorga M, Cagigal ML, Fernández F, Mazorra F: Myeloid sarcoma of the extrahepatic bile ducts presenting as obstructive jaundice. APMIS; 2006 Sep;114(9):666-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a rare case of myeloid sarcoma (MS) of the extrahepatic bile ducts presenting as obstructive jaundice in a patient without leukemia at time of diagnosis.
  • These cells exhibited medium-sized round nuclei with central nucleoli and eosinophilic cytoplasm, and were strongly positive for myeloperoxidase, CD68, lysozyme, CD45, CD117 (c-kit protein) and CD43.
  • Eight months following surgery the patient presented with multiple cutaneous nodules and bone marrow trephine biopsy showed acute myelomonocytic leukemia.
  • MS should be taken into consideration in the differential diagnosis of a patient with obstructive jaundice.
  • Immunohistochemistry is essential for a correct diagnosis.

  • Genetic Alliance. consumer health - Myeloid sarcoma.
  • MedlinePlus Health Information. consumer health - Bile Duct Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16948823.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  •  go-up   go-down


48. Nemoto T, Saito Y, Tokuhira M, Tomikawa A, Sagawa M, Haba Y, Hanzawa K, Sekiguchi Y, Watanabe R, Tamaru J, Itoyama S, Mori S, Kizaki M: [Acute-onset eosinophilic leukemia associated with tumor lysis syndrome after imatinib and steroid pulse therapy]. Rinsho Ketsueki; 2010 May;51(5):326-31
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Acute-onset eosinophilic leukemia associated with tumor lysis syndrome after imatinib and steroid pulse therapy].
  • As plural effusion due to the underlying disease progressively worsened, she was given prednisolone and hydroxyurea, but the effect was limited.
  • The WBC count rapidly decreased, but tumor lysis syndrome led to acute renal failure and disseminated intravasucular coagulation appeared.
  • [MeSH-major] Leukemia, Eosinophilic, Acute / complications. Leukemia, Eosinophilic, Acute / drug therapy. Methylprednisolone / adverse effects. Piperazines / adverse effects. Pyrimidines / adverse effects. Tumor Lysis Syndrome / etiology
  • [MeSH-minor] Acute Kidney Injury / etiology. Aged, 80 and over. Benzamides. Disseminated Intravascular Coagulation / etiology. Drug Synergism. Fatal Outcome. Female. Humans. Hypereosinophilic Syndrome / complications. Imatinib Mesylate. Pleural Effusion / etiology. Pulse Therapy, Drug

  • Hazardous Substances Data Bank. IMATINIB MESYLATE .
  • Hazardous Substances Data Bank. METHYLPREDNISOLONE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20534953.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate; X4W7ZR7023 / Methylprednisolone
  •  go-up   go-down


49. Qiu Z, Dyer KD, Xie Z, Rådinger M, Rosenberg HF: GATA transcription factors regulate the expression of the human eosinophil-derived neurotoxin (RNase 2) gene. J Biol Chem; 2009 May 8;284(19):13099-109
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The transcription factors GATA-1 and GATA-2 have been implicated in promoting differentiation of eosinophilic leukocytes.

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nat Genet. 1995 Jun;10(2):219-23 [7663519.001]
  • [Cites] Curr Mol Med. 2008 Sep;8(6):585-90 [18781965.001]
  • [Cites] J Biol Chem. 1996 May 24;271(21):12387-93 [8647842.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12370-5 [8901588.001]
  • [Cites] J Biol Chem. 1997 Jan 17;272(3):1665-9 [8999843.001]
  • [Cites] Blood. 1998 Mar 15;91(6):2126-32 [9490699.001]
  • [Cites] Curr Opin Hematol. 1999 May;6(3):164-8 [10226737.001]
  • [Cites] Blood. 1999 Aug 15;94(4):1429-39 [10438731.001]
  • [Cites] Blood. 1999 Oct 1;94(7):2333-42 [10498605.001]
  • [Cites] Semin Cell Dev Biol. 2005 Feb;16(1):129-36 [15659347.001]
  • [Cites] Ann N Y Acad Sci. 2005 Jun;1044:142-58 [15958708.001]
  • [Cites] Int J Hematol. 2005 Jun;81(5):378-84 [16158817.001]
  • [Cites] Int J Biochem Cell Biol. 2006 Jan;38(1):6-11 [16095949.001]
  • [Cites] Annu Rev Immunol. 2006;24:147-74 [16551246.001]
  • [Cites] Genes Dev. 2006 Nov 1;20(21):3010-21 [17079688.001]
  • [Cites] Blood. 2009 Jan 8;113(2):317-27 [18832658.001]
  • [Cites] J Leukoc Biol. 1999 Oct;66(4):683-8 [10534126.001]
  • [Cites] J Biol Chem. 2000 Mar 31;275(13):9425-32 [10734088.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4701-6 [10758160.001]
  • [Cites] J Allergy Clin Immunol. 2001 Aug;108(2 Suppl):S72-6 [11498676.001]
  • [Cites] Cell Mol Life Sci. 2001 Dec;58(14):2008-17 [11814053.001]
  • [Cites] Curr Opin Hematol. 2002 Mar;9(2):93-100 [11844990.001]
  • [Cites] J Exp Med. 2002 Jun 3;195(11):1379-86 [12045236.001]
  • [Cites] J Exp Med. 2002 Jun 3;195(11):1387-95 [12045237.001]
  • [Cites] J Exp Med. 2002 Jun 3;195(11):F43-7 [12045250.001]
  • [Cites] J Allergy Clin Immunol. 2002 Oct;110(4):553-64 [12373260.001]
  • [Cites] Acta Haematol. 2002;108(4):237-45 [12432220.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8811-6 [12857954.001]
  • [Cites] Am J Respir Med. 2003;2(3):245-59 [14720006.001]
  • [Cites] Mamm Genome. 2004 Feb;15(2):126-34 [15058383.001]
  • [Cites] Proc Natl Acad Sci U S A. 1981 Aug;78(8):5165-9 [6946462.001]
  • [Cites] J Allergy Clin Immunol. 1982 Nov;70(5):361-6 [7130551.001]
  • [Cites] J Exp Med. 1984 Jul 1;160(1):179-96 [6588134.001]
  • [Cites] Proc Natl Acad Sci U S A. 1989 Jun;86(12):4460-4 [2734298.001]
  • [Cites] Genes Dev. 1991 Jun;5(6):919-31 [2044960.001]
  • [Cites] Nucleic Acids Res. 1991 Oct 11;19(19):5285-91 [1656391.001]
  • [Cites] Nucleic Acids Res. 1992 Apr 11;20(7):1812 [1579480.001]
  • [Cites] Blood. 1993 Jun 15;81(12):3234-41 [8507862.001]
  • [Cites] Mol Cell Biol. 1993 Jul;13(7):4011-22 [8321208.001]
  • [Cites] Genes Dev. 1994 May 15;8(10):1184-97 [7926723.001]
  • [Cites] Exp Hematol. 1995 Feb;23(2):99-107 [7828675.001]
  • [Cites] Genes Dev. 1995 May 15;9(10):1250-62 [7758949.001]
  • [Cites] J Leukoc Biol. 1995 Jul;58(1):49-54 [7616105.001]
  • [Cites] J Immunol. 2007 Aug 1;179(3):1693-9 [17641035.001]
  • [Cites] BMC Mol Biol. 2007;8:89 [17927842.001]
  • [Cites] J Exp Med. 2008 Jan 21;205(1):79-90 [18195069.001]
  • [Cites] J Leukoc Biol. 2008 May;83(5):1079-87 [18211964.001]
  • [Cites] Curr Pharm Biotechnol. 2008 Jun;9(3):135-40 [18673278.001]
  • [Cites] J Biol Chem. 1995 Sep 15;270(37):21539-44 [7665566.001]
  • (PMID = 19279013.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] ENG
  • [Databank-accession-numbers] GENBANK/ FJ785402
  • [Grant] United States / NIAID NIH HHS / AI / AI00941; United States / NIAID NIH HHS / AI / AI00942; United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / GATA1 Transcription Factor; 0 / GATA1 protein, human; 0 / GATA2 Transcription Factor; 0 / GATA2 protein, human; 0 / RNA, Messenger; 0 / RNA, Small Interfering; EC 3.1.- / Eosinophil-Derived Neurotoxin; EC 3.1.27.5 / RNASE2 protein, human
  • [Other-IDs] NLM/ PMC2676042
  •  go-up   go-down


50. Abramson N: Chronic eosinophilic leukemia/hypereosinophilic syndrome and acute leukemia. J Clin Oncol; 2006 Apr 1;24(10):1647
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chronic eosinophilic leukemia/hypereosinophilic syndrome and acute leukemia.
  • [MeSH-major] Hypereosinophilic Syndrome / complications. Leukemia / etiology
  • [MeSH-minor] Acute Disease. Humans

  • Genetic Alliance. consumer health - Hypereosinophilic syndromes.
  • MedlinePlus Health Information. consumer health - Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] J Clin Oncol. 2005 Sep 10;23(26):6285-95 [16155011.001]
  • (PMID = 16575017.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  •  go-up   go-down


51. Horigome H, Sumazaki R, Iwasaki N, Imoto N, Kinugasa H, Saito M, Matsui A: Fatal eosinophilic heart disease in a child with neurofibromatosis-1 complicated by acute lymphoblastic leukemia. Heart Vessels; 2005 May;20(3):120-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fatal eosinophilic heart disease in a child with neurofibromatosis-1 complicated by acute lymphoblastic leukemia.
  • We present a pediatric case of neurofibromatosis-1 (NF-1) complicated by acute lymphoblastic leukemia and hypereosinophilia, which caused multiple end-organ damage.
  • When eosinophilia is diagnosed in patients with NF-1, eosinophilic end-organ damage, particularly cardiac involvement, in addition to hematological malignancies, should be screened for in order to start medical treatment at the early stage of the disease.
  • [MeSH-major] Hypereosinophilic Syndrome / complications. Neurofibromatosis 1 / complications. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications


52. Chang ST, Hsieh YC, Lee LP, Tzeng CC, Chuang SS: Acute myelomonocytic leukemia with abnormal eosinophils: a case report with multi-modality diagnostic work-up. Chang Gung Med J; 2006 Sep-Oct;29(5):532-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acute myelomonocytic leukemia with abnormal eosinophils: a case report with multi-modality diagnostic work-up.
  • Acute myeloid leukemia (AML) with recurrent genetic abnormalities often carries a favorable prognosis.
  • It is referred to as acute myelomonocytic leukemia with abnormal eosinophils (AMML Eo).
  • Marrow aspiration showed 47% blasts and 33% eosinophils, of which 19% were morphologically abnormal with both eosinophilic and basophilic cytoplasmic granules.
  • [MeSH-major] Eosinophils / pathology. Leukemia, Myelomonocytic, Acute / diagnosis

  • Genetic Alliance. consumer health - Acute Myelomonocytic Leukemia.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17214400.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  •  go-up   go-down


53. Schaffer JV, McNiff JM, Seropian S, Cooper DL, Bolognia JL: Lichen sclerosus and eosinophilic fasciitis as manifestations of chronic graft-versus-host disease: expanding the sclerodermoid spectrum. J Am Acad Dermatol; 2005 Oct;53(4):591-601
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lichen sclerosus and eosinophilic fasciitis as manifestations of chronic graft-versus-host disease: expanding the sclerodermoid spectrum.
  • Chronic cutaneous graft-versus-host disease (GVHD) is classically divided into two major clinical categories--lichenoid and sclerodermoid.
  • Eosinophilic fasciitis (EF) (a fibrosing disorder related to deep morphea) and lichen sclerosus (LS) have also been reported as manifestations of sclerodermoid GVHD.
  • EF involved the extremities (sparing the hands and feet), and was characterized clinically by an acute onset of pain and edema followed by induration with a rippled appearance.
  • [MeSH-major] Eosinophilia / etiology. Fasciitis / etiology. Graft vs Host Disease / complications. Lichen Sclerosus et Atrophicus / etiology
  • [MeSH-minor] Adult. Chronic Disease. Female. Humans. Leukemia, Myeloid, Acute / surgery. Lymphoma, Large B-Cell, Diffuse / surgery. Magnetic Resonance Imaging. Male. Middle Aged. Remission Induction. Stem Cell Transplantation


54. Sadler GM, Halbert AR, Smith N, Rogers M: Trichodysplasia spinulosa associated with chemotherapy for acute lymphocytic leukaemia. Australas J Dermatol; 2007 May;48(2):110-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Trichodysplasia spinulosa associated with chemotherapy for acute lymphocytic leukaemia.
  • We report two boys with trichodysplasia spinulosa associated with chemotherapy for acute lymphocytic leukaemia.
  • Histopathology demonstrated hair follicles dilated by a proliferation of large eosinophilic cells containing numerous abnormal trichohyaline granules.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Hair Diseases / chemically induced. Hair Follicle / virology. Immunocompromised Host. Immunosuppressive Agents / adverse effects. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy

  • MedlinePlus Health Information. consumer health - Hair Problems.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17535200.001).
  • [ISSN] 0004-8380
  • [Journal-full-title] The Australasian journal of dermatology
  • [ISO-abbreviation] Australas. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
  •  go-up   go-down


55. Bogucka-Kocka A, Smolarz HD, Kocki J: Apoptotic activities of ethanol extracts from some Apiaceae on human leukaemia cell lines. Fitoterapia; 2008 Dec;79(7-8):487-97
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apoptotic activities of ethanol extracts from some Apiaceae on human leukaemia cell lines.
  • The apoptotic activities of seven ethanol extracts from fruits of seven species of Apiaceae, Eryngium planum, Archangelica officinalis, Pastinaca sativa, Heracleum sibiricum, Carum carvi, Foeniculum vulgare, Levisticum officinale against ML-1--human acute myeloblastic leukaemia, J-45.01--human acute T cell leukaemia, EOL--human eosinophilic leukaemia, HL-60--human Caucasian promyelocytic leukaemia, 1301--human T cell leukaemia lymphoblast, C-8166--human T cell leukaemia, U-266B1--human myeloma, WICL--human Caucasian normal B cell, and H-9--human T cell, were investigated.
  • [MeSH-major] Apiaceae / chemistry. Apoptosis / drug effects. Leukemia / drug therapy. Phytotherapy. Plant Extracts / pharmacology

  • MedlinePlus Health Information. consumer health - Herbal Medicine.
  • MedlinePlus Health Information. consumer health - Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18672039.001).
  • [ISSN] 1873-6971
  • [Journal-full-title] Fitoterapia
  • [ISO-abbreviation] Fitoterapia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Plant Extracts
  •  go-up   go-down






Advertisement