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1. Al Sanosi A, Fagan PA, Biggs ND: Conservative management of acoustic neuroma. Skull Base; 2006 May;16(2):95-100

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conservative management of acoustic neuroma.
  • AIM OF STUDY: To identify those patients with vestibular schwannoma (acoustic neuroma) in whom treatment becomes necessary.
  • RESULT: A total of 205 patients with small tumors were followed for a mean of 40.8 months.
  • In 136 patients (66.3%) the tumor did not grow.
  • Eight of 197 patients (4%) had rapid growth and 6 patients (3%) had radiological evidence of tumor regression.
  • Five of these showed rapid growth, four developed ataxia in whom tumor growth was slow, three had ataxia without tumor growth, two patients developed brainstem compression, and one patient elected to proceed to surgery, although there were no tumor growth or symptoms.
  • CONCLUSION: Few patients with small tumors will come to surgery in the short term.
  • Perhaps the majority of patients with such small tumors will not need surgery.
  • Long-term follow-up studies of 20 years or more are required to be come more confident about the natural history of these tumors.

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  • (PMID = 17077873.001).
  • [ISSN] 1531-5010
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1502035
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2. Aznmi MN, Lokman BS, Ishlah L: The translabyrinthine approach for acoustic neuroma and its common complications. Med J Malaysia; 2006 Mar;61(1):72-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The translabyrinthine approach for acoustic neuroma and its common complications.
  • A retrospective analysis of 15 cases intracanalicular acoustic neuroma that undergone tumour excision by translabyrinthine approach spanning from August 1996 until December 2002 is presented.
  • Magnetic resonance imaging is the most important investigation tool to diagnose acoustic neuroma.
  • At six months post operatively, the facial nerve was normal or near normal (grade I and II) in 46.6%, grade III to IV in 46.6% and grade V to VI in 6.7% of the cases respectively.
  • [MeSH-major] Ear, Inner / surgery. Neuroma, Acoustic / surgery. Otologic Surgical Procedures / methods

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  • (PMID = 16708737.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
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3. Schoemaker MJ, Swerdlow AJ, Ahlbom A, Auvinen A, Blaasaas KG, Cardis E, Christensen HC, Feychting M, Hepworth SJ, Johansen C, Klaeboe L, Lönn S, McKinney PA, Muir K, Raitanen J, Salminen T, Thomsen J, Tynes T: Mobile phone use and risk of acoustic neuroma: results of the Interphone case-control study in five North European countries. Br J Cancer; 2005 Oct 3;93(7):842-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mobile phone use and risk of acoustic neuroma: results of the Interphone case-control study in five North European countries.
  • There is public concern that use of mobile phones could increase the risk of brain tumours.
  • If such an effect exists, acoustic neuroma would be of particular concern because of the proximity of the acoustic nerve to the handset.
  • We conducted, to a shared protocol, six population-based case-control studies in four Nordic countries and the UK to assess the risk of acoustic neuroma in relation to mobile phone use.
  • Data were collected by personal interview from 678 cases of acoustic neuroma and 3553 controls.
  • The risk of acoustic neuroma in relation to regular mobile phone use in the pooled data set was not raised (odds ratio (OR) = 0.9, 95% confidence interval (CI): 0.7-1.1).
  • The study suggests that there is no substantial risk of acoustic neuroma in the first decade after starting mobile phone use.
  • [MeSH-major] Cell Phones. Neuroma, Acoustic / etiology

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  • [CommentIn] Br J Cancer. 2006 May 8;94(9):1348-9; author reply 1352-3 [16570040.001]
  • [CommentIn] Br J Cancer. 2006 May 8;94(9):1351; author reply 1352-3 [16570042.001]
  • [CommentIn] Br J Cancer. 2006 May 8;94(9):1350; author reply 1352-3 [16570041.001]
  • (PMID = 16136046.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2361634
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4. Schoemaker MJ, Swerdlow AJ, Auvinen A, Christensen HC, Feychting M, Johansen C, Klaeboe L, Lönn S, Salminen T, Tynes T: Medical history, cigarette smoking and risk of acoustic neuroma: an international case-control study. Int J Cancer; 2007 Jan 1;120(1):103-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Medical history, cigarette smoking and risk of acoustic neuroma: an international case-control study.
  • Acoustic neuroma (vestibular schwannoma) is a benign tumor of the vestibulocochlear nerve.
  • Its recorded incidence is increasing but risk factors for this tumor have scarcely been investigated.
  • We conducted a population-based case-control study of risk factors for acoustic neuroma in the UK and Nordic countries, including 563 cases and 2,703 controls.
  • Tumor risk was analyzed in relation to medical history and cigarette smoking.
  • Risk of acoustic neuroma was significantly raised in parous compared with nulliparous women (OR = 1.7, 95% CI: 1.1-2.6), but was not related to age at first birth or number of children.
  • Risk was not associated with a history of allergic disease, past head injury, past diagnosis of a neoplasm or birth characteristics, but was significantly raised for past diagnosis of epilepsy (OR = 2.5, 95% CI: 1.3-4.9).
  • Tumor risk was significantly reduced in subjects who had ever regularly smoked cigarettes (OR = 0.7, 95% CI: 0.6-0.9), but the reduction applied only to current smokers (OR = 0.5, 95% CI: 0.4-0.6), not ex-smokers (OR = 1.0, 95% CI: 0.8-1.3).
  • The reduced risk of acoustic neuroma in smokers and raised risk in parous women might relate to sex hormone levels, or smoking might suppress tumor growth, but effects of parity and smoking on timing of diagnosis of the tumor are also a potential explanation.
  • The raised risk in relation to past diagnosis of epilepsy might be a surveillance artefact or imply that epilepsy and/or antiepileptic medication use predispose to acoustic neuroma.
  • [MeSH-major] Neuroma, Acoustic / etiology. Smoking / adverse effects


5. Dublin A: Acoustic neuroma or vestibular schwannoma? Skull Base; 2009 Sep;19(5):375

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acoustic neuroma or vestibular schwannoma?

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  • (PMID = 20190950.001).
  • [ISSN] 1532-0065
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2765706
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6. Milham S: Mobile phone use and risk of acoustic neuroma: results of the interphone case-control study in five north European countries [corrected]. Br J Cancer; 2006 May 8;94(9):1351; author reply 1352-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mobile phone use and risk of acoustic neuroma: results of the interphone case-control study in five north European countries [corrected].
  • [MeSH-major] Cell Phones. Neuroma, Acoustic / etiology
  • [MeSH-minor] Case-Control Studies. Data Interpretation, Statistical. Disease Outbreaks. Humans. Odds Ratio. Reproducibility of Results. Risk Factors

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  • [CommentOn] Br J Cancer. 2005 Oct 3;93(7):842-8 [16136046.001]
  • [ErratumIn] Br J Cancer. 2006 May 8;94(9):1354
  • (PMID = 16570042.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2361398
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7. Zanetti D, Campovecchi CB, Pasini S, Nassif N: Simultaneous translabyrinthine removal of acoustic neuroma and cochlear implantation. Auris Nasus Larynx; 2008 Dec;35(4):562-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Simultaneous translabyrinthine removal of acoustic neuroma and cochlear implantation.
  • OBJECTIVES: To report of a 65-year-old woman with bilateral Meniere's disease was referred for cochlear implantation (CI) due to severe/profound sensorineural hearing loss.
  • METHODS: During the assessment workup, a vestibular schwannoma in the right ear was found by MR imaging.
  • She underwent a translabyrinthine removal of the acoustic neuroma (AN) with sparing of the cochlear nerve and concurrent ipsilateral CI with a Nucleus Freedom device (Cochlear Ltd., Lane Cove, New South Wales, Australia).
  • CONCLUSION: Cochlear implantation at the time of acoustic neuroma removal with VIII nerve sparing can be a safe and effective hearing restoration procedure.
  • [MeSH-major] Cochlear Implantation. Hearing Loss, Sensorineural / surgery. Neuroma, Acoustic / surgery
  • [MeSH-minor] Aged. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Meniere Disease / diagnosis. Speech Discrimination Tests

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  • (PMID = 18243617.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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8. Rimaaja T, Haanpää M, Blomstedt G, Färkkilä M: Headaches after acoustic neuroma surgery. Cephalalgia; 2007 Oct;27(10):1128-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Headaches after acoustic neuroma surgery.
  • Headache and depression were studied in patients who had undergone operation for acoustic neuroma.
  • Headache after acoustic neuroma operation appears to be a specific subgroup of postcraniotomy headache.
  • [MeSH-major] Craniotomy / adverse effects. Headache / classification. Headache / etiology. Neuroma, Acoustic / surgery. Postoperative Complications

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  • (PMID = 17711494.001).
  • [ISSN] 0333-1024
  • [Journal-full-title] Cephalalgia : an international journal of headache
  • [ISO-abbreviation] Cephalalgia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal
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9. Kundi M: What can be learned from the Japanese study of mobile phone use and acoustic neuroma? Occup Environ Med; 2008 Jun;65(6):428; author reply 428
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] What can be learned from the Japanese study of mobile phone use and acoustic neuroma?
  • [MeSH-major] Cell Phones. Neoplasms, Radiation-Induced / etiology. Neuroma, Acoustic / etiology

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  • [CommentOn] Occup Environ Med. 2006 Dec;63(12):802-7 [16912083.001]
  • (PMID = 18487430.001).
  • [ISSN] 1470-7926
  • [Journal-full-title] Occupational and environmental medicine
  • [ISO-abbreviation] Occup Environ Med
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
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10. Nelson PD, Toledano MB, McConville J, Quinn MJ, Cooper N, Elliott P: Trends in acoustic neuroma and cellular phones: is there a link? Neurology; 2006 Jan 24;66(2):284-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Trends in acoustic neuroma and cellular phones: is there a link?
  • [MeSH-major] Cell Phones / utilization. Neuroma, Acoustic / epidemiology

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  • (PMID = 16434678.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Argiris K, Andreou Z: Re: Evaluation of cost effectiveness for conservative and active management strategies for acoustic neuroma. Clin Otolaryngol; 2010 Feb;35(1):69-70; author reply 70-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Re: Evaluation of cost effectiveness for conservative and active management strategies for acoustic neuroma.
  • [MeSH-major] Neuroma, Acoustic / economics. Neuroma, Acoustic / surgery. Otorhinolaryngologic Surgical Procedures / economics. Otorhinolaryngologic Surgical Procedures / methods

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  • [CommentOn] Clin Otolaryngol. 2009 Oct;34(5):438-46 [19793276.001]
  • (PMID = 20447172.001).
  • [ISSN] 1749-4486
  • [Journal-full-title] Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • [ISO-abbreviation] Clin Otolaryngol
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
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12. Gal TJ, Shinn J, Huang B: Current epidemiology and management trends in acoustic neuroma. Otolaryngol Head Neck Surg; 2010 May;142(5):677-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Current epidemiology and management trends in acoustic neuroma.
  • OBJECTIVE: The objective of this study was to assess the epidemiology of acoustic neuroma and determine current trends in therapy using tumor registry techniques.
  • SUBJECTS AND METHODS: The Surveillance Epidemiology and End Results (SEER) database is a national tumor registry that began to identify and abstract benign and borderline tumors of the brain and central nervous system in the year 2004.
  • Coding for International Classification of Diseases for Oncology (ICD-O-3) codes for schwannoma (9560/0) with collaborative staging (CS) coding for acoustic nerve (72.4) was used to identify acoustic neuromas.
  • Demographic data, tumor size, and treatment data were analyzed.
  • RESULTS: A total of 1621 patients with acoustic neuroma were identified, for an incidence rate of 1.1/100,000.
  • Tumors were equally distributed across gender and tumor laterality, with the majority (84%) occurring in Caucasians.
  • Of tumors less than 2 cm, 27.2 percent were treated with radiotherapy.
  • Statistically significant associations were observed with the increased use of radiotherapy for small (< 2 cm) tumors (P = 0.0001).
  • [MeSH-major] Neuroma, Acoustic / epidemiology. Neuroma, Acoustic / therapy

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  • [Copyright] Copyright 2010 American Academy of Otolaryngology-Head and Neck Surgery Foundation. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20416455.001).
  • [ISSN] 1097-6817
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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13. Stripf T, Mann WJ: [Ocular tilt reaction. A rare complication after acoustic neuroma surgery]. HNO; 2005 Dec;53(12):1077-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ocular tilt reaction. A rare complication after acoustic neuroma surgery].
  • Visual disturbances after acoustic neuroma surgery are very rare complications.
  • We present a patient with diplopia after a middle fossa approach for resection of an acoustic neuroma.
  • It is generally agreed that this reaction is secondary to a dysfunction of the tonic bilateral vestibular inputs that stabilize the eyes and head in a normal upright position in the roll plane.
  • It has also been described after denervation of the utricle and injury of the brain stem.
  • [MeSH-major] Diplopia / diagnosis. Diplopia / etiology. Neuroma, Acoustic / surgery. Neurosurgical Procedures / adverse effects

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  • (PMID = 15660240.001).
  • [ISSN] 0017-6192
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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14. Kernohan MD, Blackmore KJ, Johnson IJ, Zammit-Maempel I: Magnetic resonance imaging: is a single scan ever enough for the diagnosis of acoustic neuroma? J Laryngol Otol; 2006 Dec;120(12):1061-3
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  • [Title] Magnetic resonance imaging: is a single scan ever enough for the diagnosis of acoustic neuroma?
  • The MRI scan was initially negative but when repeated seven years later, following a further deterioration of symptoms, it showed a 2 mm, right-sided acoustic neuroma.
  • This case has great potential significance for the diagnosis of acoustic neuroma, and it may raise medico-legal issues regarding the exclusion of this diagnosis.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Neuroma, Acoustic / diagnosis

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  • (PMID = 17059619.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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15. Andersen HT, Schrøder SA, Bonding P: Unilateral deafness after acoustic neuroma surgery: subjective hearing handicap and the effect of the bone-anchored hearing aid. Otol Neurotol; 2006 Sep;27(6):809-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unilateral deafness after acoustic neuroma surgery: subjective hearing handicap and the effect of the bone-anchored hearing aid.
  • OBJECTIVE: To evaluate the subjective hearing handicap in patients with unilateral deafness after acoustic neuroma surgery and the effect of the Bone-anchored Hearing Aid (BAHA) on test band.
  • STUDY DESIGN: Fifty-nine consecutive patients with unilateral deafness after translabyrintine removal of an acoustic neuroma, treated in Denmark in 2001 and 2002, were included.
  • CONCLUSION: This study shows that unilateral deafness after acoustic neuroma surgery is thought as a handicap in most of the patients and confirms that treatment with the BAHA has positive subjective effects and improves speech discrimination in noise.
  • Data from centers that perform simultaneous acoustic neuroma surgery and implantation for BAHA are necessary for firm conclusions.
  • [MeSH-major] Bone Conduction. Hearing Aids. Hearing Loss, Unilateral / etiology. Hearing Loss, Unilateral / therapy. Neuroma, Acoustic / surgery. Otologic Surgical Procedures / adverse effects

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  • (PMID = 16885786.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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16. Magliulo G, D'Amico R, Celebrini A, Cuiuli G: Postoperative Ramsay-Hunt syndrome after acoustic neuroma resection. Viral reactivation. An Otorrinolaringol Ibero Am; 2005;32(3):253-9
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  • [Title] Postoperative Ramsay-Hunt syndrome after acoustic neuroma resection. Viral reactivation.
  • The aim of this paper is to present a patient suffering from acoustic neuroma and operated on with immediate postoperative hearing and facial function preservation who developed delayed Ramsay-Hunt syndrome.
  • [MeSH-major] Herpes Zoster Oticus / etiology. Herpes Zoster Oticus / virology. Neuroma, Acoustic / surgery. Postoperative Complications

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  • (PMID = 16001695.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antiviral Agents; X4HES1O11F / Acyclovir
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17. Zverina E: [Acoustic neuroma--vestibular schwannoma--personal experience of up-to-date management]. Cas Lek Cesk; 2010;149(6):269-76
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  • [Title] [Acoustic neuroma--vestibular schwannoma--personal experience of up-to-date management].
  • [Transliterated title] Neurinom akustiku--vestibulární schwannom--osobní pohled na nejmodernejsí postupy v jeho lécbe.
  • Acoustic neuroma, properly called vestibular schwannoma, arises from the Schwann cells of the vestibular transitional zone of the vestibulocochlear nerve as the most frequent tumour of the posterior fossa.
  • Its incidence is estimated at 1.2 vestibular schwannoma per a population of 100,000/year.
  • As to size, vestibular schwannoma is classified into grades I to IV.
  • About one third of small vestibular schwannoma show hardly any growth, the larger ones grow aggressively.
  • The author's conclusion is based on 33 years of experience with hundreds of surgically treated vestibular schwannoma (now at the ENT Department of Head and Neck Surgery, CU 1st Medical Faculty and FN Teaching Hospital, Prague Motol).
  • Irradiation for larger vestibular schwannoma is decreasingly efficacious.
  • 3. Microsurgery with intraoperative monitoring of facial and acoustic nerve function offers scope for radical removal of vestibular schwannoma of any size (grades I-IV) and for the preservation of facial nerve function and, of late, hearing, too.
  • [MeSH-major] Neuroma, Acoustic

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  • (PMID = 20662473.001).
  • [ISSN] 0008-7335
  • [Journal-full-title] Casopís lékar̆ů c̆eských
  • [ISO-abbreviation] Cas. Lek. Cesk.
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Czech Republic
  • [Number-of-references] 50
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18. Brooker J, Burney S, Fletcher J, Dally M: A qualitative exploration of quality of life among individuals diagnosed with an acoustic neuroma. Br J Health Psychol; 2009 Sep;14(Pt 3):563-78
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A qualitative exploration of quality of life among individuals diagnosed with an acoustic neuroma.
  • OBJECTIVES: To explore quality of life outcomes and the factors that influenced adjustment among individuals diagnosed with an acoustic neuroma.
  • METHODS: Twenty-one participants who had been diagnosed with and/or treated for an acoustic neuroma since 2000 attended one of four focus groups.
  • [MeSH-major] Adaptation, Psychological. Neuroma, Acoustic / psychology. Quality of Life / psychology

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  • (PMID = 19055870.001).
  • [ISSN] 1359-107X
  • [Journal-full-title] British journal of health psychology
  • [ISO-abbreviation] Br J Health Psychol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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19. Kondziolka D, Lunsford LD: Future perspectives in acoustic neuroma management. Prog Neurol Surg; 2008;21:247-54
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  • [Title] Future perspectives in acoustic neuroma management.
  • Management options for patients with vestibular schwannomas (acoustic neuromas) include observation, resection, stereotactic radiosurgery, or fractionated radiotherapy.
  • There has been an evolution in available technologies, and an evolution in both patient and physician approaches to the management of this tumor.
  • [MeSH-major] Neuroma, Acoustic / surgery. Radiosurgery / trends

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  • (PMID = 18810226.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 65
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20. Wandong S, Meng L, Xingang L, Yuguang L, Shugan Z, Lei W, Chengyuan W: Cystic acoustic neuroma. J Clin Neurosci; 2005 Apr;12(3):253-5
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  • [Title] Cystic acoustic neuroma.
  • To define the clinical characteristics of cystic acoustic neuroma, we retrospectively analyzed 22 patients with cystic acoustic neuroma and reviewed the literature with regard to clinical manifestation, imaging features, diagnosis, surgical procedures and prognosis.
  • An acoustic neuroma was defined as cystic according to the following criteria: the presence of hypodense/hypointense areas on CT or MRI, the identification of cystic elements at operation and histological verification.
  • At the end of surgery, the facial nerve was anatomically intact in 86.4% of cystic acoustic neuromas.
  • Complete removal of the tumor was achieved in 18 cases (81.8%).
  • We conclude that patients with cystic acoustic neuroma need prompt surgery with special attention paid to the preservation of the facial nerve.
  • [MeSH-major] Neuroma, Acoustic / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Facial Nerve / surgery. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neurosurgical Procedures. Prognosis. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15851076.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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21. Smouha EE, Yoo M, Mohr K, Davis RP: Conservative management of acoustic neuroma: a meta-analysis and proposed treatment algorithm. Laryngoscope; 2005 Mar;115(3):450-4
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  • [Title] Conservative management of acoustic neuroma: a meta-analysis and proposed treatment algorithm.
  • OBJECTIVES/HYPOTHESES: Conservative management is a viable treatment alternative for acoustic neuroma.
  • METHODS: Published studies on conservative management of acoustic neuroma were found using a key word search through PubMed in addition to the bibliographies of these selected studies.
  • A spreadsheet was made to tabulate the selection criteria for conservative management, duration and frequency of follow-up, patient demographics, initial tumor size and rate of growth, change in hearing status, and the need for definitive treatment.
  • The average initial tumor size was 11.8 mm (n = 900); 43% of 1,244 acoustic neuromas showed growth, whereas 57% showed either no growth or tumor regression.
  • CONCLUSIONS: Our meta-analysis supports the role of conservative management of acoustic neuromas in properly selected patients on the basis of a slow overall rate of growth and a substantial incidence of no growth.
  • An algorithm for acoustic neuroma management is proposed based on initial tumor size, patient age, and hearing status.
  • [MeSH-major] Algorithms. Neuroma, Acoustic / therapy

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  • [CommentIn] Laryngoscope. 2005 Sep;115(9):1704; author reply 1704 [16148723.001]
  • (PMID = 15744156.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis
  • [Publication-country] United States
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22. Bergson E, Sataloff RT: Preoperative computerized dynamic posturography as a prognostic indicator of balance function in patients with acoustic neuroma. Ear Nose Throat J; 2005 Mar;84(3):154-6
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  • [Title] Preoperative computerized dynamic posturography as a prognostic indicator of balance function in patients with acoustic neuroma.
  • We conducted a study to determine the prognostic reliability of preoperative computerized dynamic posturography (CDP) in patients undergoing surgical excision of an acoustic neuroma.
  • [MeSH-major] Diagnosis, Computer-Assisted. Neuroma, Acoustic / diagnosis. Neuroma, Acoustic / surgery. Posture. Sensation Disorders / diagnosis
  • [MeSH-minor] Adult. Aged. Cohort Studies. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neurosurgical Procedures / methods. Postural Balance / physiology. Predictive Value of Tests. Preoperative Care / methods. Retrospective Studies. Risk Assessment. Sensitivity and Specificity. Treatment Outcome. Vestibular Function Tests

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  • (PMID = 15871583.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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23. Cokkeser Y, Ilhan A: Late midbrain compression by liquefied fat in a case operated for an acoustic neuroma. Otolaryngol Head Neck Surg; 2006 Nov;135(5):807-9
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  • [Title] Late midbrain compression by liquefied fat in a case operated for an acoustic neuroma.
  • [MeSH-major] Adipose Tissue / transplantation. Fats / adverse effects. Mesencephalon. Neuroma, Acoustic / surgery

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  • (PMID = 17071319.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fats
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24. Trang TT, Megerian CA: I cannot smile or wink anymore: facial nerve weakness after acoustic neuroma surgery. Curr Surg; 2005 Mar-Apr;62(2):156-61; quiz 161

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  • [Title] I cannot smile or wink anymore: facial nerve weakness after acoustic neuroma surgery.

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  • [CommentOn] Laryngoscope. 2000 Sep;110(9):1539-42 [10983957.001]
  • (PMID = 15796934.001).
  • [ISSN] 0149-7944
  • [Journal-full-title] Current surgery
  • [ISO-abbreviation] Curr Surg
  • [Language] eng
  • [Publication-type] Comment; Journal Article
  • [Publication-country] United States
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25. Kim AH, Edwards BM, Telian SA, Kileny PR, Arts HA: Transient evoked otoacoustic emissions pattern as a prognostic indicator for hearing preservation in acoustic neuroma surgery. Otol Neurotol; 2006 Apr;27(3):372-9
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  • [Title] Transient evoked otoacoustic emissions pattern as a prognostic indicator for hearing preservation in acoustic neuroma surgery.
  • OBJECTIVE: To determine whether pre-operative transient otoacoustic emission (TEOAE) patterns are predictive of successful hearing preservation in acoustic neuroma surgery.
  • PATIENTS: A convenience sample was identified in whom pre-operative TEOAE data were available in patients undergoing acoustic neuroma surgery from 1993-2004.
  • Other variables of prognostic significance to hearing preservation in our series included smaller tumor size, tumor location within the IAC, better pre-operative hearing, and shorter latencies on ABR.
  • CONCLUSION: A robust pre-operative TEOAE frequency band pattern may be used as a favorable prognostic indicator for potential hearing preservation in acoustic neuroma surgery.
  • The prognostic value may be enhanced when combined with other prognostic factors such as tumor size, tumor location, pre-operative ABR and audiometric results.
  • [MeSH-major] Auditory Threshold. Hearing Loss / prevention & control. Neuroma, Acoustic / surgery. Otoacoustic Emissions, Spontaneous / physiology
  • [MeSH-minor] Adolescent. Adult. Aged. Facial Nerve Diseases / etiology. Female. Humans. Logistic Models. Male. Middle Aged. Predictive Value of Tests. Preoperative Care. Prognosis. Retrospective Studies. Treatment Outcome

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  • (PMID = 16639277.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Lin V, Jacobson M, Dorion J, Chen J, Nedzelski J: Global assessment of outcomes after varying reinnervation techniques for patients with facial paralysis subsequent to acoustic neuroma excision. Otol Neurotol; 2009 Apr;30(3):408-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Global assessment of outcomes after varying reinnervation techniques for patients with facial paralysis subsequent to acoustic neuroma excision.
  • OBJECTIVE: To determine whether there are objective and/or subjective differences in facial function, tongue function and quality of life in patients who have undergone 1) direct facial-to-facial (Primary, 4 patients), 2) direct facial-to-hypoglossal (End-to-End, 7 patients), 3) end-to-side facial-to-hypoglossal nerve anastomoses with sural nerve/greater auricular nerve interposition (End-to-Side with Interposition Graft, 7 patients), and 4) end-to-side facial-to-hypoglossal nerve anastomoses (End-to-Side, 7 patients) after acoustic neuroma excision.
  • METHODS: Twenty-five patients with complete facial paralysis after acoustic neuroma surgery who have also undergone 1 of 4 types of facial musculature reinnervation volunteered for the study.
  • CONCLUSION: Complete sacrifice of the ipsilateral hypoglossal nerve does present with clinically and statistically significant morbidity in patients.
  • [MeSH-major] Facial Nerve / surgery. Facial Paralysis / etiology. Facial Paralysis / surgery. Neuroma, Acoustic / surgery. Neurosurgical Procedures. Postoperative Complications / surgery
  • [MeSH-minor] Adult. Anastomosis, Surgical. Disability Evaluation. Female. Functional Laterality / physiology. Humans. Hypoglossal Nerve / surgery. Male. Middle Aged. Quality of Life. Retrospective Studies. Surveys and Questionnaires. Tongue / innervation. Tongue / physiology. Treatment Outcome

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  • (PMID = 19318893.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Kalogeridi MA, Georgolopoulou P, Kouloulias V, Kouvaris J, Pissakas G: Long-term follow-up confirms the efficacy of linac radiosurgery for acoustic neuroma and meningioma patients. A single institution's experience. J BUON; 2010 Jan-Mar;15(1):68-73
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  • [Title] Long-term follow-up confirms the efficacy of linac radiosurgery for acoustic neuroma and meningioma patients. A single institution's experience.
  • PURPOSE: To investigate the long-term efficacy and toxicity in a group of consecutive patients treated with linear accelerator (linac) radiosurgery for acoustic neuromas and meningiomas.
  • METHODS: Between 2000 and 2004, 34 patients (median age 65.5 years, range 50-84) with acoustic neuroma or meningioma were treated with linac-based stereotactic radiosurgery with a surface dose of 11-15.5 Gy.
  • Median tumor volume was 5.95cm(3).
  • Nineteen (59%) tumors decreased in size and 13 (41%) remained stable.
  • None of the tumors increased in size in the long-term follow-up, resulting in an overall growth control of 100% for the small number of patients of our study.
  • CONCLUSION: Long-term follow-up confirms the efficacy and low toxicity of linac radiosurgery for neuroma and meningioma patients.
  • [MeSH-major] Meningeal Neoplasms / surgery. Meningioma / surgery. Neuroma, Acoustic / surgery. Particle Accelerators. Radiosurgery / instrumentation
  • [MeSH-minor] Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Radiation Dosage. Time Factors. Tomography, X-Ray Computed. Treatment Outcome. Tumor Burden

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  • (PMID = 20414930.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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28. Nyberg G, Kinnefors A, Gudjonson O, Svedberg A, Edfeldt L, Rask-Andersen H: [Brain stem implant can restore hearing. Treatment of deafness in bilateral acoustic neuroma]. Lakartidningen; 2007 Nov 21-27;104(47):3553-6
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  • [Title] [Brain stem implant can restore hearing. Treatment of deafness in bilateral acoustic neuroma].
  • [Transliterated title] Hjärnstamsimplantat kan återge hörsel. Behandling av dövhet vid dubbelsidiga akustikusneurinom.
  • [MeSH-major] Auditory Brain Stem Implantation. Deafness / surgery. Neurofibromatosis 2 / surgery. Neuroma, Acoustic / surgery
  • [MeSH-minor] Adult. Auditory Brain Stem Implants / adverse effects. Auditory Brain Stem Implants / contraindications. Child. Humans. Magnetic Resonance Imaging. Treatment Outcome

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  • (PMID = 18203590.001).
  • [ISSN] 0023-7205
  • [Journal-full-title] Läkartidningen
  • [ISO-abbreviation] Lakartidningen
  • [Language] swe
  • [Publication-type] Journal Article; Review
  • [Publication-country] Sweden
  • [Number-of-references] 10
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29. Martin TP: Conservative management of acoustic neuroma: a meta-analysis and proposed treatment algorithm. Laryngoscope; 2005 Sep;115(9):1704; author reply 1704
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  • [Title] Conservative management of acoustic neuroma: a meta-analysis and proposed treatment algorithm.
  • [MeSH-major] Neuroma, Acoustic / therapy

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  • [CommentOn] Laryngoscope. 2005 Mar;115(3):450-4 [15744156.001]
  • (PMID = 16148723.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
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30. Hardell L, Hansson Mild K: Mobile phone use and risk of acoustic neuroma: results of the interphone case-control study in five North European countries. Br J Cancer; 2006 May 8;94(9):1348-9; author reply 1352-3
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  • [Title] Mobile phone use and risk of acoustic neuroma: results of the interphone case-control study in five North European countries.
  • [MeSH-major] Cell Phones. Neuroma, Acoustic / etiology

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  • (PMID = 16570040.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
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31. Schwager K, Baier G, Helms J, Hagen R: [Results in otosurgically treated patients with acoustic neuroma. Part 2: Hearing results after middle fossa approach]. Laryngorhinootologie; 2008 Sep;87(9):629-33
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  • [Title] [Results in otosurgically treated patients with acoustic neuroma. Part 2: Hearing results after middle fossa approach].
  • [Transliterated title] Ergebnisse otochirurgisch operierter Patienten mit Akustikusneurinom. Teil 2: Hörergebnisse nach transtemporaler Resektion.
  • BACKGROUND: The surgical therapy of acoustic neuromas has been seen critically lately.
  • There was no difference between tumors confined to the inner ear canal and tumors extending into the cerebello pontine angle.
  • There was also no difference between tumors up to a volume of 100 mm3 and tumors between 100 mm3 and 500 mm3.
  • CONCLUSION: Acoustic neuroma confined to the internal meatus or with little extend into the cerebello pontine angle (i. e. no contact to structures of the brain stem or vessels of the posterior fossa) are feasible for resection via the middle fossa approach.
  • The possibility of hearing preservation and low morbidity makes it the treatment of choice for this group of tumors.
  • [MeSH-major] Hearing / physiology. Neuroma, Acoustic / surgery

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  • (PMID = 18421644.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Germany
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32. Bisi MA, Selaimen CM, Chaves KD, Bisi MC, Grossi ML: Vestibular schwannoma (acoustic neuroma) mimicking temporomandibular disorders: a case report. J Appl Oral Sci; 2006 Dec;14(6):476-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vestibular schwannoma (acoustic neuroma) mimicking temporomandibular disorders: a case report.
  • Approximately 6 to 16% of patients with trigeminal neuralgia symptoms present intracranial tumors, the most common being the vestibular schwannoma (acoustic neuroma).
  • In these cases, magnetic resonance imaging (MRI) has proved to be a useful tool in tumor diagnosis.
  • The purpose of this paper is to demonstrate the relationship among trigeminal neuralgia symptoms, intracranial tumors and temporomandibular dysfunction by presenting a clinical case.

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  • (PMID = 19089251.001).
  • [ISSN] 1678-7765
  • [Journal-full-title] Journal of applied oral science : revista FOB
  • [ISO-abbreviation] J Appl Oral Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Other-IDs] NLM/ PMC4327303
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33. Gouveris H, Mewes T, Maurer J, Mann W: Steroid and vasoactive treatment for acute deafness after attempted hearing preservation acoustic neuroma surgery. ORL J Otorhinolaryngol Relat Spec; 2005;67(1):30-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Steroid and vasoactive treatment for acute deafness after attempted hearing preservation acoustic neuroma surgery.
  • OBJECTIVE: To investigate whether intravenous steroid and vasoactive therapy in the acute postoperative period improves hearing outcome in patients who develop acute deafness after attempted hearing preservation surgery for acoustic neuroma (AN) through a retrosigmoid or a middle cranial fossa approach.
  • [MeSH-major] Anti-Inflammatory Agents / therapeutic use. Deafness / drug therapy. Deafness / etiology. Hydroxyethyl Starch Derivatives / therapeutic use. Neuroma, Acoustic / surgery. Pentoxifylline / therapeutic use. Postoperative Complications. Prednisolone / therapeutic use. Salvage Therapy / methods. Vasodilator Agents / therapeutic use
  • [MeSH-minor] Acute Disease. Drug Therapy, Combination. Evoked Potentials, Auditory, Brain Stem / physiology. Humans. Injections, Intravenous. Retrospective Studies

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  • [Copyright] Copyright (c) 2005 S. Karger AG, Basel.
  • (PMID = 15753619.001).
  • [ISSN] 0301-1569
  • [Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties
  • [ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Hydroxyethyl Starch Derivatives; 0 / Vasodilator Agents; 9PHQ9Y1OLM / Prednisolone; SD6QCT3TSU / Pentoxifylline
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34. Wai Y, Chu J, Wang C, Lin Y, Lin G, Wan Y, Wang J: An integrated diffusion map for the analysis of diffusion properties: a feasibility study in patients with acoustic neuroma. Acad Radiol; 2009 Apr;16(4):428-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An integrated diffusion map for the analysis of diffusion properties: a feasibility study in patients with acoustic neuroma.
  • Diffusion tensor imaging was acquired from nine healthy volunteers and four patients with acoustic neuroma before and 3 months after the stereotactic radiosurgery.
  • Five regions of interest were selected from healthy subjects and the whole tumor from the patients.
  • [MeSH-major] Algorithms. Diffusion Magnetic Resonance Imaging / methods. Image Enhancement / methods. Image Interpretation, Computer-Assisted / methods. Neuroma, Acoustic / diagnosis. Neuroma, Acoustic / surgery. Subtraction Technique

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  • (PMID = 19268854.001).
  • [ISSN] 1878-4046
  • [Journal-full-title] Academic radiology
  • [ISO-abbreviation] Acad Radiol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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35. Liu BY, Tian YJ, Liu W, Liu SL, Qiao H, Zhang JT, Jia GJ: Intraoperative facial motor evoked potentials monitoring with transcranial electrical stimulation for preservation of facial nerve function in patients with large acoustic neuroma. Chin Med J (Engl); 2007 Feb 20;120(4):323-5
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  • [Title] Intraoperative facial motor evoked potentials monitoring with transcranial electrical stimulation for preservation of facial nerve function in patients with large acoustic neuroma.
  • The aim of this study was to investigate the effect of intraoperative facial motor evoked potentials monitoring with transcranial electrical stimulation on preservation of facial nerve function.
  • METHOD: From January to November 2005, 19 patients with large acoustic neuroma were treated using intraoperative facial motor evoked potentials monitoring with transcranial electrical stimulation (TCEMEP) for preservation of facial nerve function.
  • The relationship between the decrease of MEP amplitude after tumor removal and the postoperative function of the facial nerve was analyzed.
  • CONCLUSIONS: Intraoperative TCEMEP can be used to predict postoperative function of the facial nerve.
  • [MeSH-major] Electric Stimulation Therapy. Evoked Potentials, Motor. Facial Nerve / physiopathology. Monitoring, Intraoperative. Neuroma, Acoustic / physiopathology

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  • (PMID = 17374285.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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36. Lunsford LD, Niranjan A, Flickinger JC, Maitz A, Kondziolka D: Radiosurgery of vestibular schwannomas: summary of experience in 829 cases. J Neurosurg; 2005 Jan;102(s_supplement):195-199

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiosurgery of vestibular schwannomas: summary of experience in 829 cases.
  • OBJECT: Management options for vestibular schwannomas (VSs) have greatly expanded since the introduction of stereotactic radiosurgery.
  • Optimal outcomes reflect long-term tumor control, preservation of cranial nerve function, and retention of quality of life.
  • The average tumor volume was 2.5 cm<sup>3</sup>.
  • The median margin dose to the tumor was 13 Gy (range 10-20 Gy).
  • Unchanged hearing preservation was possible in 50 to 77% of patients (up to 90% in those with intracanalicular tumors).
  • Trigeminal symptoms were detected in less than 3% of patients whose tumors reached the level of the trigeminal nerve.
  • Tumor control rates at 10 years were 97% (no additional treatment needed).
  • Gamma knife surgery provides a low risk, minimally invasive treatment option for patients with newly diagnosed or residual vs. Cranial nerve preservation and quality of life maintenance are possible in long-term follow up.

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  • (PMID = 28306432.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / radiosurgery / vestibular schwannoma
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37. Lin VY, Houlden D, Bethune A, Nolan M, Pirouzmand F, Rowed D, Nedzelski JM, Chen JM: A novel method in predicting immediate postoperative facial nerve function post acoustic neuroma excision. Otol Neurotol; 2006 Oct;27(7):1017-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A novel method in predicting immediate postoperative facial nerve function post acoustic neuroma excision.
  • To determine whether the percentage calculated by dividing the amplitude of postexcision direct facial nerve stimulus responses (at pontomedullary junction) by the amplitude of distal ipsilateral transcutaneous (stylomastoid region) maximal stimulus responses and response amplitude progression by increasing stimulus intensities have predictive value for determining normal or near-normal (House-Brackmann Grade 1 or 2) immediate postoperative facial nerve function.
  • Postexcision direct facial nerve stimulation at the pontomedullary junction and transcutaneous maximal facial nerve stimulation at the ipsilateral stylomastoid region and their associated response amplitudes were recorded.
  • PATIENTS AND METHODS: Patients who underwent acoustic neuroma surgery from January 2004 to March 2006 with intraoperative facial nerve monitoring and an intact facial nerve after tumor excision were included.
  • CONCLUSION: The percentage of the response amplitude of direct facial nerve stimulation at the pontomedullary junction when compared with the maximum response amplitude of ipsilateral transcutaneous stimulation at the stylomastoid foramen is a good predictor of normal to near-normal immediate postoperative facial nerve function.
  • Progression of amplitude response also seems to be a good predictor of normal to near-normal immediate postoperative facial nerve function.
  • [MeSH-major] Facial Nerve / physiopathology. Monitoring, Intraoperative. Neuroma, Acoustic / surgery
  • [MeSH-minor] Adult. Aged. Electric Stimulation. Facial Nerve Injuries / prevention & control. Facial Paralysis / prevention & control. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Treatment Outcome

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  • (PMID = 17006353.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Chung WY, Liu KD, Shiau CY, Wu HM, Wang LW, Guo WY, Ming-Tak Ho D, Hung-Chi Pan D: Gamma knife surgery for vestibular schwannoma: 10-year experience of 195 cases. J Neurosurg; 2005 Jan;102(s_supplement):87-97

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gamma knife surgery for vestibular schwannoma: 10-year experience of 195 cases.
  • OBJECT: The authors conducted a study to determine the optimal radiation dose for vestibular schwannoma (VS) and to examine the histopathology in cases of treatment failure for better understanding of the effects of irradiation.
  • Seventy-two patients (37%) had undergone partial or total excision of their tumor prior to gamma knife surgery (GKS).
  • The mean tumor volume was 4.1 cm<sup>3</sup> (range 0.04-23.1 cm<sup>3</sup>).
  • Multiisocenter dose planning placed a prescription dose of 11 to 18.2 Gy on the 50 to 94% isodose located at the tumor margin.
  • At the latest MR imaging assessment decreased or stable tumor volume was demonstrated in 93.6% of the patients.
  • Uncontrolled tumor swelling was noted in five patients at 3.5, 17, 24, 33, and 62 months after GKS, respectively.
  • Histopathological examination of specimens in three cases (one at 62 months after GKS) revealed a long-lasting radiation effect on vessels inside the tumor.
  • A margin 12-Gy dose with homogeneous distribution is effective in preventing tumor progression, while posing no serious threat to normal cranial nerve function.

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  • (PMID = 28306447.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / stereotaxy / vestibular schwannoma
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39. Sameshima T, Fukushima T, McElveen JT Jr, Friedman AH: Critical assessment of operative approaches for hearing preservation in small acoustic neuroma surgery: retrosigmoid vs middle fossa approach. Neurosurgery; 2010 Sep;67(3):640-4; discussion 644-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Critical assessment of operative approaches for hearing preservation in small acoustic neuroma surgery: retrosigmoid vs middle fossa approach.
  • BACKGROUND: For hearing preservation in acoustic neuroma (AN) surgery, the middle fossa (MF) or retrosigmoid (RS) approach can be used.
  • METHODS: We reviewed 504 consecutive AN resections performed between November 1998 and September 2007 and identified 43 MF and 82 RS approaches for tumors smaller than 1.5 cm during hearing preservation surgery.
  • Individual cases were examined postoperatively with respect to hearing ability, facial nerve activity, operative time, blood loss, and symptoms resulting from retraction of the cerebellar or temporal lobes.
  • Temporary facial nerve weakness was more frequent in the MF group (P = .0249).
  • CONCLUSIONS: Although hearing and facial nerve function assessed at approximately 1 year was similar with these 2 approaches, the RS approach provided several advantages over the MF approach for ANs smaller than 1.5 cm.
  • [MeSH-major] Cranial Fossa, Middle / surgery. Cranial Fossa, Posterior / surgery. Craniotomy / methods. Hearing Loss / prevention & control. Neuroma, Acoustic / surgery. Neurosurgical Procedures / methods

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  • (PMID = 20647969.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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40. Parsa AT: Acoustic neuroma. Preface. Neurosurg Clin N Am; 2008 Apr;19(2):xi-xii
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acoustic neuroma. Preface.
  • [MeSH-major] Neuroma, Acoustic / history

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  • (PMID = 18534332.001).
  • [ISSN] 1558-1349
  • [Journal-full-title] Neurosurgery clinics of North America
  • [ISO-abbreviation] Neurosurg. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Editorial; Historical Article; Introductory Journal Article
  • [Publication-country] United States
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41. Lunsford LD: Foreword. Acoustic neuroma. Prog Neurol Surg; 2008;21:XI-XV
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Foreword. Acoustic neuroma.
  • [MeSH-major] Neuroma, Acoustic / surgery. Radiosurgery

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  • (PMID = 19004132.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Introductory Journal Article
  • [Publication-country] Switzerland
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42. Myrseth E, Møller P, Wentzel-Larsen T, Goplen F, Lund-Johansen M: Untreated Vestibular Schwannoma: Vertigo is a Powerful Predictor for Health-Related Quality of Life. Neurosurgery; 2006 Jul 01;59(1):67-76

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Untreated Vestibular Schwannoma: Vertigo is a Powerful Predictor for Health-Related Quality of Life.

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  • (PMID = 28180608.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Hasegawa T, Kida Y, Yoshimoto M, Koike J, Goto K: TABLEEvaluation of Tumor Expansion after Stereotactic Radiosurgery in Patients Harboring Vestibular Schwannomas. Neurosurgery; 2006 Jun 01;58(6):1119-1128

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] TABLEEvaluation of Tumor Expansion after Stereotactic Radiosurgery in Patients Harboring Vestibular Schwannomas.

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  • (PMID = 28173267.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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44. Schere D, Silberstein SD: Intravenous lidocaine infusion for the treatment of post-acoustic neuroma resection headache: a case report. Headache; 2009 Feb;49(2):302-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intravenous lidocaine infusion for the treatment of post-acoustic neuroma resection headache: a case report.
  • Presentation of a case report of a 47-year-old male with a post-acoustic neuroma resection intractable headache responding to intravenous lidocaine infusion.
  • [MeSH-minor] Analgesics, Opioid / therapeutic use. Humans. Infusions, Intravenous. Male. Mexiletine / therapeutic use. Middle Aged. Neuroma, Acoustic / surgery. Otologic Surgical Procedures / adverse effects

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  • (PMID = 18549411.001).
  • [ISSN] 1526-4610
  • [Journal-full-title] Headache
  • [ISO-abbreviation] Headache
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Analgesics, Opioid; 0 / Anesthetics, Local; 1U511HHV4Z / Mexiletine; 98PI200987 / Lidocaine
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45. Wowra B, Muacevic A, Jess-Hempen A, Hempel JM, Müller-Schunk S, Tonn JC: Outpatient gamma knife surgery for vestibular schwannoma: definition of the therapeutic profile based on a 10-year experience. J Neurosurg; 2005 Jan;102(s_supplement):114-118
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Outpatient gamma knife surgery for vestibular schwannoma: definition of the therapeutic profile based on a 10-year experience.
  • OBJECT: The purpose of the study was to define the therapeutic profile of outpatient gamma knife surgery (GKS) for vestibular schwannoma (VS) by using sequential tumor volumetry to quantify changes following treatment.
  • The actuarial 6-year tumor control rate after a single GKS treatment was 95%.
  • Tumor swelling was observed in 43 patients (38.7%).
  • Recurrence was significantly associated with NF2 (p < 0.003) and the reduced dose (p < 0.03) delivered to these tumors.
  • The incidence of facial nerve neuropathy was mainly determined by surgery prior to GKS (p < 0.0001).
  • Facial nerve radiation toxicity was mild and transient.
  • No permanent facial nerve toxicity was observed.
  • The risk of hearing loss was correlated with age and transient tumor swelling (p < 0.05) but not with dose parameters or NF2.

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  • (PMID = 28306422.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / tumor volumetry / vestibular schwannoma
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46. Patrinou A, Malindretos P, Koutroubas G, Anagnostou N, Argiraki E, Syrganis C: A rare retroperitoneal schwannoma in a patient with neurofibromatosis Type 2. NDT Plus; 2010 Jun;3(3):288-290

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare retroperitoneal schwannoma in a patient with neurofibromatosis Type 2.
  • Neurofibromatosis Type 2 (NF2) is a dominantly inherited tumour-prone disorder, characterized by the development of multiple schwannomas, meningiomas and ependymomas.
  • Vestibular schwannoma (VS) is the hallmark of NF2.
  • Retroperitoneal schwannomas are expected to occur in only 3% of cases.
  • We present the case of a large retroperitoneal schwannoma in a patient with NF2.
  • Brain, orbits, cervical, thoracic and lumbar MRI revealed bilateral VS, multiple meningiomas as well as multiple schwannomas and ependymomas in the cervical, thoracic and lumbar spine.
  • The retroperitoneal mass represents a schwannoma probably derived from an intercostal nerve.

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  • (PMID = 28657039.001).
  • [ISSN] 1753-0784
  • [Journal-full-title] NDT plus
  • [ISO-abbreviation] NDT Plus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; meningioma / neurofibromatosis Type 2 / retroperitoneal / schwannoma
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47. Huang WL, Hsieh MH, Liao SC: Acoustic neuroma identified after electroconvulsive therapy in a patient with recurrent major depression and undifferentiated somatoform disorder. J ECT; 2010 Dec;26(4):330-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acoustic neuroma identified after electroconvulsive therapy in a patient with recurrent major depression and undifferentiated somatoform disorder.
  • Little is known about the safety of electroconvulsive therapy (ECT) in patients with brain tumors, especially in patients with acoustic neuroma, which is difficult to diagnose early.
  • For patients with somatoform disorder, physicians may alter the sensitivity to the somatic complaints, making it even more difficult to make an early diagnosis of "silent" brain tumors.
  • This report describes a rare case involving treatment of refractory major depression and somatoform disorder that developed into increased intracranial pressure after ECT, possibly due to an undiagnosed acoustic neuroma.
  • It is suggested that for patients with refractory major depression with somatoform disorders, the threshold of suspicion for silent tumors should be lowered and pre-ECT brain imaging study should be performed, specifically when the pattern of symptoms of the central nervous system-related somatoform syndrome changes.
  • [MeSH-major] Cranial Nerve Neoplasms / diagnosis. Depressive Disorder, Major / complications. Electroconvulsive Therapy. Neuroma, Acoustic / diagnosis. Somatoform Disorders / complications
  • [MeSH-minor] Anesthesia. Brain / pathology. Drug Resistance. Female. Humans. Intracranial Pressure. Magnetic Resonance Imaging. Middle Aged. Recurrence


48. van Eck AT, Horstmann GA: Increased preservation of functional hearing after gamma knife surgery for vestibular schwannoma. J Neurosurg; 2005 Jan;102(s_supplement):204-206

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Increased preservation of functional hearing after gamma knife surgery for vestibular schwannoma.
  • OBJECT: Gamma knife surgery (GKS) for vestibular schwannoma is still associated with an additional hearing loss of approximately 30%.
  • The mean tumor volume was 2.28 cm<sup>3</sup>.
  • After a mean follow-up duration of 22 months, the magnetic resonance imaging-based tumor control rate was 87%.
  • One patient suffered transient facial nerve impairment.
  • CONCLUSIONS: Reducing the maximum dose to 20 Gy seems to be an effective treatment, which probably increases preservation of functional hearing without sacrificing the high tumor control rates achieved in radiosurgery.
  • Post-radiosurgery tumor swelling occurred in 25% of the cases and was not correlated with hearing deterioration.

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  • (PMID = 28306452.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; acoustic neurinoma / gamma knife surgery / hearing preservation / tumor swelling / vestibular schwannoma
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49. Yang SM, Yu LM, Yu LM, Han DY: [Technique of hearing preservation during acoustic neuroma surgery]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Aug;43(8):564-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Technique of hearing preservation during acoustic neuroma surgery].
  • OBJECTIVE: To explore the possibility of hearing protection in acoustic neurinoma (AN) resection and to evaluate the effect of dynamic auditory monitoring and the effect of oto-endoscope for hearing protection.
  • Maximal diameters of the tumor varied between 12 and 33 millimeters with an average of 19.9 millimeters.
  • All cases were operated on by retrosigmoid approach with routine facial nerve monitoring.
  • RESULTS: In all 18 cases, tumors were resected completely in 16 cases, but sub-totally removed in 2 cases which were II neurofibromatosis.
  • In all 18 cases, there were 5 cases with tumor diameter more than 20 millimeters, in which only 2 cases of them preserved hearing function (2/5).
  • However, 9 cases preserved their hearing function in the other 13 cases whose tumors diameter less than 20 millimeters (69.2%, 9/13).
  • During operative monitoring, when drilling posterior lip of internal auditory canal (IAC), dragging and electric coagulating nearby IAC, especially clamping labyrinthine artery, removing tumor in IAC or electric coagulating arachnoid blood vessel on the top of tumor tissue, the ABR waves were affected greatly.
  • [MeSH-major] Hearing Loss / prevention & control. Neuroma, Acoustic / surgery. Otologic Surgical Procedures

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  • (PMID = 18959258.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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50. Hariharan S, Zhu J, Nadkarni MA, Donahue JE: Metastatic lung cancer in the cerebellopontine angles mimicking bilateral acoustic neuroma. J Clin Neurosci; 2005 Feb;12(2):184-6
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  • [Title] Metastatic lung cancer in the cerebellopontine angles mimicking bilateral acoustic neuroma.
  • Bilateral cerebellopontine angle (CPA) tumors identified on MRI are considered bilateral acoustic neuromas, the definitive diagnostic criterion of neurofibromatosis 2 (NF-2).
  • MRI revealed bilateral enhancing CPA lesions, which were suggestive of acoustic neuromas and a diagnosis of NF-2.
  • Therefore, metastatic carcinoma to the CPA can mimic bilateral acoustic neuromas; imaging studies alone may be insufficient to diagnose NF-2.
  • [MeSH-major] Adenocarcinoma / secondary. Brain Neoplasms / secondary. Cerebellopontine Angle / pathology. Lung Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Neuroma, Acoustic


51. Harsha WJ, Backous DD: Counseling patients on surgical options for treating acoustic neuroma. Otolaryngol Clin North Am; 2005 Aug;38(4):643-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Counseling patients on surgical options for treating acoustic neuroma.
  • The selection of surgical approach for the removal of AN is a complex one, depending on factors related to specific tumor anatomy, patient characteristics, and the familiarity and skill level of the skull base team.Overall, the literature supports that surgical outcomes are acceptable in regard to tumor removal, patient safety, and complication rates.
  • The inconsistent reporting methods in the current literature make it difficult to assess logically the rates for hearing preservation, facial nerve outcome, and complications as controlled for tumor size and other preoperative patient characteristics.
  • The best conclusions would be from prospective surgical trials controlling for patient factors, size of the tumor, and experience of the skull base team.
  • [MeSH-major] Neuroma, Acoustic / surgery. Otorhinolaryngologic Surgical Procedures
  • [MeSH-minor] Cerebrospinal Fluid Otorrhea / etiology. Cerebrospinal Fluid Rhinorrhea. Counseling. Facial Nerve. Humans. Postoperative Complications. Treatment Outcome

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  • (PMID = 16005723.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Cardoso AC, Fernandes YB, Ramina R, Borges G: Acoustic neuroma (vestibular schwannoma): surgical results on 240 patients operated on dorsal decubitus position. Arq Neuropsiquiatr; 2007 Sep;65(3A):605-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acoustic neuroma (vestibular schwannoma): surgical results on 240 patients operated on dorsal decubitus position.
  • OBJECTIVE: To evaluate the result of the surgical treatment of vestibular schwannoma (VS) operated in dorsal decubitus (mastoid position).
  • METHOD: 240 patients with a VS underwent a retrosigmoid craniotomy for tumor resection in dorsal decubitus (mastoid position).
  • RESULTS: Complete tumor removal was achieved in 99% of the cases, with a mortality of 1.6%.
  • The facial nerve function was preserved in 85% of cases and hearing in 40% of the patients (with preoperative hearing) with tumors of up 1.5 cm in diameter.
  • [MeSH-major] Cranial Nerve Neoplasms / surgery. Craniotomy / standards. Neuroma, Acoustic / surgery. Supine Position. Vestibulocochlear Nerve / surgery. Vestibulocochlear Nerve Diseases / surgery

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  • (PMID = 17876399.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Fibrin Tissue Adhesive; 0 / Tissue Adhesives
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53. Perks JR, El-Hamri K, Blackburn TP, Plowman PN: Comparison of radiosurgery planning modalities for acoustic neuroma with regard to conformity and mean target dose. Stereotact Funct Neurosurg; 2005;83(4):165-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of radiosurgery planning modalities for acoustic neuroma with regard to conformity and mean target dose.
  • MATERIALS AND METHODS: Seven patients with acoustic neuromas deemed clinically suitable for linear accelerator or Gamma Knife radiosurgery were planned such that the minimum doses for any plan were equal.
  • [MeSH-major] Neuroma, Acoustic / surgery. Radiosurgery / methods. Radiotherapy Planning, Computer-Assisted

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 16319520.001).
  • [ISSN] 1011-6125
  • [Journal-full-title] Stereotactic and functional neurosurgery
  • [ISO-abbreviation] Stereotact Funct Neurosurg
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Switzerland
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54. Lee DJ, Maseyesva B, Westra W, Long D, Niparko JK, Califano J: Microsatellite analysis of recurrent vestibular schwannoma (acoustic neuroma) following stereotactic radiosurgery. Otol Neurotol; 2006 Feb;27(2):213-9
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  • [Title] Microsatellite analysis of recurrent vestibular schwannoma (acoustic neuroma) following stereotactic radiosurgery.
  • HYPOTHESIS: Genetic and immunohistochemical studies may provide insight into the mechanisms of vestibular schwannoma (VS) recurrence following radiation therapy.
  • BACKGROUND: Stereotactic radiation therapy is an increasingly common alternative to microsurgical resection for the primary management of sporadic vs. The molecular mechanisms associated with recurrent vestibular schwannoma (VS) following radiation therapy are not known.
  • METHODS: Primary or irradiated VS tumors were fresh-frozen at the time of surgical resection and microdissected to undergo DNA extraction.
  • Paired normal and tumor DNA specimens were analyzed for allelic loss by PCR amplification of polymorphic dinucleotide repeat sequences.
  • Deletions on chromosome 10 are seen in both benign and higher-grade meningiomas and intracranial malignancies associated with radiotherapy.
  • [MeSH-major] Chromosomes, Human, Pair 22. Microsatellite Repeats. Neoplasm Recurrence, Local / genetics. Neuroma, Acoustic / genetics. Neuroma, Acoustic / surgery. Radiosurgery
  • [MeSH-minor] Base Sequence. Chi-Square Distribution. Chromosomes, Human, Pair 10. DNA Mutational Analysis. DNA, Neoplasm / blood. DNA, Neoplasm / chemistry. DNA, Neoplasm / genetics. DNA, Neoplasm / isolation & purification. Gene Expression Regulation, Neoplastic. Genes, bcl-2 / genetics. Genes, p53 / genetics. Humans. Immunohistochemistry. Loss of Heterozygosity. Neurofibromin 2 / analysis. Neurofibromin 2 / genetics

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  • (PMID = 16436992.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Neurofibromin 2
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55. Kano H, Kondziolka D, Khan A, Flickinger JC, Lunsford LD: Predictors of hearing preservation after stereotactic radiosurgery for acoustic neuroma. J Neurosurg; 2009 Oct;111(4):863-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictors of hearing preservation after stereotactic radiosurgery for acoustic neuroma.
  • OBJECT: Many patients with acoustic neuromas (ANs) have hearing function at diagnosis and desire to maintain it.
  • To date, radiosurgical techniques have been focused on conformal irradiation of the tumor mass, with less attention to inner ear structures for which there was scant radiobiological information.
  • The authors of this study evaluated tumor control and hearing preservation as they relate to tumor volume, imaging characteristics, and nerve and cochlear radiation dose following stereotactic radiosurgery (SRS) using the Gamma Knife.
  • The median tumor volume was 0.75 cm(3) (range 0.07-7.7 cm(3)), and the median radiation dose to the tumor margin was 12.5 Gy (range 12-13 Gy).
  • At diagnosis, a greater distance from the lateral tumor to the end of the internal auditory canal correlated with better hearing function.
  • Significant prognostic factors for serviceable hearing preservation were (all pre-SRS) GR Class I hearing, an SDS >or= 80%, a PTA < 20 dB, a patient age < 60 years, an intracanalicular tumor location, and a tumor volume < 0.75 cm(3).
  • Tumor volume and anatomy relate to the hearing level before radiosurgery and influence technique.
  • [MeSH-major] Hearing Loss / prevention & control. Neuroma, Acoustic / surgery. Radiosurgery / methods

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  • (PMID = 19284227.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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56. Fortnum H, O'Neill C, Taylor R, Lenthall R, Nikolopoulos T, Lightfoot G, O'Donoghue G, Mason S, Baguley D, Jones H, Mulvaney C: The role of magnetic resonance imaging in the identification of suspected acoustic neuroma: a systematic review of clinical and cost effectiveness and natural history. Health Technol Assess; 2009 Mar;13(18):iii-iv, ix-xi, 1-154
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  • [Title] The role of magnetic resonance imaging in the identification of suspected acoustic neuroma: a systematic review of clinical and cost effectiveness and natural history.
  • OBJECTIVE(S): To evaluate the clinical effectiveness and cost-effectiveness of a range of diagnostic strategies for investigating patients with unilateral hearing loss and/or tinnitus, with a view to confirming or eliminating a diagnosis of acoustic neuroma, and to describe the natural history of acoustic neuroma.
  • ABR has high sensitivity compared with MR imaging for acoustic neuromas greater than 1 cm in size but not for smaller neuromas.
  • Non-contrast-enhanced MR imaging was found to be a more cost-effective test for acoustic neuroma than GdT1W MR imaging.
  • The incidence of acoustic neuroma has increased over the last 30 years, with the median age at diagnosis remaining at 55 years.
  • The pattern and rate of growth of acoustic neuroma are highly variable and currently unpredictable.
  • Given the recent improvement in resolution and reduction in cost of MR imaging, ABR can no longer be considered appropriate as the primary test used to screen for acoustic neuroma.
  • Based on a cost-effectiveness model developed to reflect UK practice it was concluded that a diagnostic algorithm that deploys non-contrast MR imaging as an initial imaging screen in the investigation of acoustic neuroma is less costly than and likely to be as effective as available contrast MR imaging.
  • [MeSH-major] Neuroma, Acoustic / diagnosis. Neuroma, Acoustic / economics
  • [MeSH-minor] Age Distribution. Cost-Benefit Analysis. Evoked Potentials, Auditory, Brain Stem. Hearing Tests. Humans. Incidence. Magnetic Resonance Imaging. Prevalence. Reproducibility of Results. Technology Assessment, Biomedical

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  • (PMID = 19358774.001).
  • [ISSN] 2046-4924
  • [Journal-full-title] Health technology assessment (Winchester, England)
  • [ISO-abbreviation] Health Technol Assess
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 244
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57. Bird PA, MacFarlane MR: Management of unilateral vestibular schwannoma/acoustic neuroma. N Z Med J; 2007;120(1265):U2805
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of unilateral vestibular schwannoma/acoustic neuroma.
  • [MeSH-major] Neuroma, Acoustic / therapy

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  • (PMID = 18264185.001).
  • [ISSN] 1175-8716
  • [Journal-full-title] The New Zealand medical journal
  • [ISO-abbreviation] N. Z. Med. J.
  • [Language] eng
  • [Publication-type] Editorial; Review
  • [Publication-country] New Zealand
  • [Number-of-references] 6
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58. Orabi AA, D'Souza AR, Walsh RR, Irving RM: The influence of the Internet on decision making in acoustic neuroma. J Laryngol Otol; 2005 Oct;119(10):806-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The influence of the Internet on decision making in acoustic neuroma.
  • OBJECTIVE: To determine the access to and the use of the Internet by acoustic neuroma patients as a medical information source, and the influence of the Internet on decision-making, as well as the patients' views on the quality of particular sites.
  • MATERIALS AND METHODS: A retrospective 27-item questionnaire was sent to 138 consecutive acoustic neuroma patients diagnosed between 1997 and 2002.
  • Twenty-four per cent accessed the Internet to obtain information about acoustic neuromas.
  • Acoustic neuroma specialists and ENT surgeons in general should familiarize themselves with related websites so that patients can then be directed to high-quality sites.
  • [MeSH-major] Decision Making. Information Services / utilization. Internet / utilization. Neuroma, Acoustic / therapy

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  • (PMID = 16259658.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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59. Samkange-Zeeb F, Schlehofer B, Schüz J, Schlaefer K, Berg-Beckhoff G, Wahrendorf J, Blettner M: Occupation and risk of glioma, meningioma and acoustic neuroma: results from a German case-control study (interphone study group, Germany). Cancer Epidemiol; 2010 Feb;34(1):55-61
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  • [Title] Occupation and risk of glioma, meningioma and acoustic neuroma: results from a German case-control study (interphone study group, Germany).
  • BACKGROUND: Several epidemiological studies have investigated the association between occupation and brain tumour risk, but results have been inconclusive.
  • We investigated the association between six occupational categories defined a priori: chemical, metal, agricultural, construction, electrical/electronic and transport, and the risk of glioma, meningioma and acoustic neuroma.
  • RESULTS: Most of the observed odds ratios were close to 1.0 for ever having worked in the six occupational sectors and risk of glioma, meningioma and acoustic neuroma.
  • [MeSH-major] Brain Neoplasms / epidemiology. Glioma / epidemiology. Meningeal Neoplasms / epidemiology. Meningioma / epidemiology. Neuroma, Acoustic / epidemiology. Occupational Diseases / epidemiology


60. Shaffer BT, Cohen MS, Bigelow DC, Ruckenstein MJ: Validation of a disease-specific quality-of-life instrument for acoustic neuroma: the Penn Acoustic Neuroma Quality-of-Life Scale. Laryngoscope; 2010 Aug;120(8):1646-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Validation of a disease-specific quality-of-life instrument for acoustic neuroma: the Penn Acoustic Neuroma Quality-of-Life Scale.
  • OBJECTIVES/HYPOTHESIS: To design and validate the first disease-specific quality-of-life instrument for acoustic neuroma, the Penn Acoustic Neuroma Quality-of-Life (PANQOL) scale.
  • METHODS: One hundred forty-three patients with acoustic neuromas completed the 80-question preliminary instrument and the general Short Form-36 Health Survey (SF-36).
  • PANQOL face domain scores showed significant differences across the House-Brackmann grading system scores and correlated inversely with tumor size.
  • The PANQOL scale discriminated acoustic neuroma cases from controls better than the SF-36.
  • CONCLUSIONS: We have developed the first validated disease-specific quality of life instrument for patients with acoustic neuromas.
  • Given the lack of a validated equivalent, this tool has the potential to become a critical outcome measure for studies evaluating treatment of patients with acoustic neuromas.
  • [MeSH-major] Health Status Indicators. Neuroma, Acoustic / diagnosis. Quality of Life

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  • (PMID = 20641085.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] United States
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61. Piedra MP, Scheithauer BW, Driscoll CL, Link MJ: Primary Melanocytic Tumor of the Cerebellopontine Angle Mimicking a Vestibular Schwannoma. Neurosurgery; 2006 Jul 01;59(1):E206

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary Melanocytic Tumor of the Cerebellopontine Angle Mimicking a Vestibular Schwannoma.

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  • (PMID = 28180621.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Cafer S, Bayramoglu I, Uzum N, Yilmaz M, Memis L, Uygur K: Expression and clinical significance of Ki-67, oestrogen and progesterone receptors in acoustic neuroma. J Laryngol Otol; 2008 Feb;122(2):125-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression and clinical significance of Ki-67, oestrogen and progesterone receptors in acoustic neuroma.
  • OBJECTIVE: The objective was to assess the presence of Ki-67, and oestrogen and progesterone hormone receptors as well as their clinical correlates in acoustic neuroma.
  • METHODS: Medical records of 59 patients who were operated on for acoustic neuroma between 1995 and 2003 were evaluated retrospectively.
  • Formaldehyde-fixed paraffin-embedded archival acoustic neuroma specimens of the patients were used for immunohistochemical assessments of oestrogen and progesterone hormone receptors, and Ki-67 proliferative marker.
  • CONCLUSION: Oestrogen is not an important hormone in acoustic neuroma due to the absence of oestrogen receptor expression in the tissue samples.
  • Since the progesterone receptor is expressed in all acoustic neuroma samples, further studies are necessary to find out about the inhibitory effect of antiprogesterone treatment on acoustic neuroma growth, which may be important particularly in elderly people or high-risk patients.
  • Although Ki-67 is expressed in the majority of acoustic neuromas, it is not an important marker in clinical practice due to a lack of any correlation with the clinical parameters.
  • [MeSH-major] Biomarkers, Tumor / chemistry. Ki-67 Antigen / metabolism. Neuroma, Acoustic / metabolism. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Cell Nucleus / metabolism. Disease Progression. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Male. Middle Aged. Retrospective Studies

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  • (PMID = 17666143.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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63. Wilson CM, Ronan SL: Rehabilitation postfacial reanimation surgery after removal of acoustic neuroma: a case study. J Neurol Phys Ther; 2010 Mar;34(1):41-9
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  • [Title] Rehabilitation postfacial reanimation surgery after removal of acoustic neuroma: a case study.
  • The purpose of this case study was to describe the details of a physical therapy evaluation and intervention for a patient who underwent facial muscle transfer after resection of acoustic neuroma.
  • [MeSH-major] Facial Paralysis / rehabilitation. Neuroma, Acoustic / surgery. Physical Therapy Modalities. Postoperative Complications / rehabilitation

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  • (PMID = 20212367.001).
  • [ISSN] 1557-0584
  • [Journal-full-title] Journal of neurologic physical therapy : JNPT
  • [ISO-abbreviation] J Neurol Phys Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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64. Salahaldin AH, Bener A: Long-term and frequent cellular phone use and risk of acoustic neuroma. Int Tinnitus J; 2006;12(2):145-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term and frequent cellular phone use and risk of acoustic neuroma.
  • Human exposure to radio frequency radiation has increased dramatically during recent years from widespread use of mobile phones, and in some studies this exposure has been linked to the development of acoustic neuroma.
  • The aim of our study was to describe the epidemiology of acoustic neuroma in a newly developed country, Qatar.
  • We reviewed all cases of acoustic neuroma registered at the Hamad Medical Corporation during the period 2004-2005.
  • During the study period, we diagnosed acoustic neuroma in 13 patients (10 women, median age 55 years, and 3 men, median age 49 years).
  • Most of the cell phones were used daily for an average of 14 times per day (range, 8-20 times) and had been used for the duration of more than 5 years, with the exception of 3 patients who had used the cell phone excessively (> 20 minutes per call more than five times daily) owing to the nature of their jobs.
  • In conclusion, the incidence of acoustic neuroma in Qatar is slightly higher than that in other countries.
  • [MeSH-major] Cell Phones / utilization. Neuroma, Acoustic / etiology

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  • (PMID = 17260880.001).
  • [ISSN] 0946-5448
  • [Journal-full-title] The international tinnitus journal
  • [ISO-abbreviation] Int Tinnitus J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Filipo R, Attanasio G, De Seta E, Viccaro M: Post-operative Herpes simplex virus encephalitis after surgical resection of acoustic neuroma: a case report. J Laryngol Otol; 2005 Jul;119(7):558-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Post-operative Herpes simplex virus encephalitis after surgical resection of acoustic neuroma: a case report.
  • The appearance of a strong headache followed by impairment of consciousness and hypertone of arms and legs complicated the post-operative course in a 33-year-old patient who underwent surgical removal of an acoustic neuroma.
  • Several brain magnetic resonance imaging (MRI) and computed tomography scans performed in the first week after onset of symptoms of infection did not establish a proper diagnosis.
  • Diffusion-weighted MRI detected brain abnormalities on the fourth day after onset of symptoms, and polymerase chain reaction identification of HSV 1 DNA confirmed the diagnosis.
  • [MeSH-major] Encephalitis, Herpes Simplex / etiology. Neuroma, Acoustic / surgery. Postoperative Complications / etiology


66. Chang SD, Gibbs IC, Sakamoto GT, Lee E, Oyelese A, Adler JR Jr: Staged stereotactic irradiation for acoustic neuroma. Neurosurgery; 2005 Jun;56(6):1254-61; discussion 1261-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Staged stereotactic irradiation for acoustic neuroma.
  • OBJECTIVE: Stereotactic radiosurgery has proven effective in the treatment of acoustic neuromas.
  • Prior reports using single-stage radiosurgery consistently have shown excellent tumor control, but only up to a 50 to 73% likelihood of maintaining hearing at pretreatment levels.
  • Staged, frame-based radiosurgery using 12-hour interfraction intervals previously has been shown by our group to achieve excellent tumor control while increasing the rate of hearing preservation at 2 years to 77%.
  • The arrival of CyberKnife (Accuray, Inc., Sunnyvale, CA) image-guided radiosurgery now makes it more practical to treat acoustic neuroma with a staged approach.
  • In this retrospective study, we report our experience with staged radiosurgery for managing acoustic neuromas.
  • METHODS: Since 1999, the CyberKnife has been used to treat more than 270 patients with acoustic neuroma at Stanford University.
  • Among the treated patients, the mean transverse tumor diameter was 18.5 mm, whereas the total marginal dose was either 18 or 21 Gy using three 6- or 7-Gy fractions.
  • Only one treated tumor (2%) progressed after radiosurgery; 29 (48%) of 61 decreased in size and 31 (50%) of the 61 tumors were stable.
  • In no patients did new trigeminal dysfunction develop, nor did any patient experience permanent injury to their facial nerve; two patients experienced transient facial twitching that resolved in 3 to 5 months.
  • CONCLUSION: Although still preliminary, these results indicate that improved tumor dose homogeneity and a staged treatment regimen may improve hearing preservation in acoustic neuroma patients undergoing stereotactic radiosurgery.
  • [MeSH-major] Cranial Nerve Neoplasms / surgery. Neuroma, Acoustic / surgery. Radiosurgery / methods

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  • (PMID = 15918941.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
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67. Tufarelli D, Meli A, Labini FS, Badaracco C, De Angelis E, Alesii A, Falcioni M, Sanna M: Balance impairment after acoustic neuroma surgery. Otol Neurotol; 2007 Sep;28(6):814-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Balance impairment after acoustic neuroma surgery.
  • OBJECTIVE: The aim of this study was to assess the incidence of balance problems after acoustic neuroma surgery, evaluating whether disequilibrium is disabling.
  • PATIENTS: A group of 386 patients who underwent acoustic neuroma surgery.
  • INTERVENTIONS: Patients were selected from a population of 459 subjects who had undergone surgery for acoustic neuroma.
  • CONCLUSION: Disequilibrium influences handicap and disability after acoustic neuroma surgery.
  • [MeSH-major] Cranial Nerve Neoplasms / complications. Cranial Nerve Neoplasms / surgery. Neuroma, Acoustic / complications. Neuroma, Acoustic / surgery. Postoperative Complications / physiopathology. Postural Balance / physiology. Vestibulocochlear Nerve Diseases / complications. Vestibulocochlear Nerve Diseases / surgery
  • [MeSH-minor] Adult. Disability Evaluation. Dizziness / physiopathology. Female. Humans. Male. Middle Aged. Surveys and Questionnaires. Vestibular Function Tests

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  • (PMID = 17948359.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Scarlett A, Bird P, Macfarlane M: Conductive hearing loss after removal of acoustic neuroma. Otol Neurotol; 2008 Jun;29(4):553-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conductive hearing loss after removal of acoustic neuroma.
  • OBJECTIVE: To report 4 patients who have developed a conductive and/or mixed hearing loss due to dehiscence of the inner ear after retrosigmoid approach for removal of acoustic neuroma.
  • PATIENTS: Four patients who presented with conductive and/or mixed hearing loss after retrosigmoid approach for removal of acoustic neuroma.
  • CONCLUSION: The occurrence of conductive hearing loss after the surgical removal of an acoustic neuroma has not previously been documented.
  • Computed tomographic scan of the temporal bones showing inner ear dehiscence may explain this finding.
  • [MeSH-major] Cranial Nerve Neoplasms / complications. Cranial Nerve Neoplasms / surgery. Hearing Loss, Conductive / etiology. Hearing Loss, Conductive / physiopathology. Neuroma, Acoustic / complications. Neuroma, Acoustic / surgery. Postoperative Complications / physiopathology. Vestibulocochlear Nerve Diseases / complications. Vestibulocochlear Nerve Diseases / surgery
  • [MeSH-minor] Acoustic Impedance Tests. Adult. Aged. Audiometry. Female. Hearing Aids. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Otologic Surgical Procedures. Otoscopy. Petrous Bone / pathology. Speech Perception. Tomography, X-Ray Computed

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  • (PMID = 18451754.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Baier G, Schwager K, Helms J, Hagen R: [Results in otosurgically treated patients with acoustic neuroma. Part 1: Facial nerve function after translabyrinthine and middle fossa resection]. Laryngorhinootologie; 2008 Aug;87(8):565-72
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  • [Title] [Results in otosurgically treated patients with acoustic neuroma. Part 1: Facial nerve function after translabyrinthine and middle fossa resection].
  • [Transliterated title] Ergebnisse otochirurgisch operierter Patienten mit Akustikusneurinom. Fazialisfunktion nach translabyrinthärer und transtemporaler resektion.
  • BACKGROUND: Regardless of all efforts to preserve a residual hearing, facial nerve function is still the primary issue for patients with acoustic neuromas.
  • There was no difference between intrameatal tumors and tumors extending beyond the porus.
  • Regular facial nerve function was seen in 93 %, postoperatively.
  • CONCLUSION: Acoustic neuroma confined to the internal meatus or with minor extension into the cerebello-pontine angle (i. e. no contact to structures of the brain stem or vessels of the posterior fossa) are feasible for resection via a middle fossa or translabyrinthine approach.
  • The possibility of hearing preservation combined with low morbidity and good results of facial nerve function makes these approaches the treatment of choice for this group of tumors.
  • [MeSH-major] Ear, Inner / surgery. Facial Nerve Injuries / diagnosis. Facial Paralysis / diagnosis. Neuroma, Acoustic / surgery. Postoperative Complications / diagnosis. Temporal Bone / surgery

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  • (PMID = 18421647.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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70. Ray J, D'Souza AR, Chavda SV, Walsh AR, Irving RM: Dissemination of fat in CSF: a common finding following translabyrinthine acoustic neuroma surgery*. Clin Otolaryngol; 2005 Oct;30(5):405-8
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  • [Title] Dissemination of fat in CSF: a common finding following translabyrinthine acoustic neuroma surgery*.
  • DESIGN: A retrospective review of translabyrinthine acoustic neuroma removal with free fat autograft obliteration of the temporal bone defect between the years 1997 and 2000.
  • [MeSH-major] Fats / analysis. Neuroma, Acoustic / surgery

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  • (PMID = 16232242.001).
  • [ISSN] 1749-4478
  • [Journal-full-title] Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • [ISO-abbreviation] Clin Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Fats
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71. Douglas SA, Yeung P, Daudia A, Gatehouse S, O'Donoghue GM: Spatial hearing disability after acoustic neuroma removal. Laryngoscope; 2007 Sep;117(9):1648-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spatial hearing disability after acoustic neuroma removal.
  • OBJECTIVES/HYPOTHESIS: Previous studies on hearing loss (HL) after acoustic neuroma removal concentrate mainly on pure-tone hearing results rather than hearing disability.
  • Our objectives were to use the Speech, Spatial and Qualities of Hearing scale (SSQ), a comprehensively validated questionnaire, to characterize and quantify the auditory disabilities that patients experience with a profound unilateral HL after acoustic neuroma removal.
  • STUDY DESIGN: Forty-four patients with profound unilateral HL after acoustic neuroma surgery completed the SSQ.
  • RESULTS: In comparison with controls, with use of analysis of variance, acoustic neuroma patients scored poorly on all items except for the identification of sounds and objects (P = .123).
  • [MeSH-major] Hearing Loss, Unilateral / etiology. Neuroma, Acoustic / surgery. Postoperative Complications

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  • (PMID = 18062043.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / K24 AR02098; United States / NIADDK NIH HHS / AM / N01 AM62271; United States / NIAMS NIH HHS / AR / N01 AR22200; United States / NIAMS NIH HHS / AR / N01 AR22201; United States / NIAMS NIH HHS / AR / N01 AR72233
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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72. Bluhm EC, Zahm SH, Fine HA, Black PM, Loeffler JS, Shapiro WR, Selker RG, Inskip PD: Personal hair dye use and risks of glioma, meningioma, and acoustic neuroma among adults. Am J Epidemiol; 2007 Jan 1;165(1):63-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Personal hair dye use and risks of glioma, meningioma, and acoustic neuroma among adults.
  • Risks for brain tumors are not well understood.
  • The authors investigated associations between use of synthetic hair dyes and risk of brain tumors in a hospital-based case-control study.
  • The study included adults newly diagnosed with glioma (n = 489), meningioma (n = 197), or acoustic neuroma (n = 96) between 1994 and 1998 at three urban US hospitals and 799 controls.
  • There was no consistent pattern of elevated odds ratios for glioma, meningioma, or acoustic neuroma with use or prolonged use of permanent, semipermanent, temporary, or gradual hair dyes.
  • Although use of permanent brown hair dye for 20 or more years was associated with glioma among women, the estimate was imprecise (odds ratio = 3.8, 95% confidence interval: 1.2, 12.5) and was based on just 13 exposed cases; thus, this could be a chance finding.
  • Overall, there was little consistent evidence for an association of synthetic hair dye use with glioma, meningioma, or acoustic neuroma.
  • [MeSH-major] Brain Neoplasms / epidemiology. Environmental Exposure / adverse effects. Glioma / epidemiology. Hair Dyes / toxicity. Meningioma / epidemiology. Neuroma, Acoustic / epidemiology


73. Lei T, Li L: [Prevention of facial nerve injury in acoustic neuroma microsurgery]. Zhonghua Wai Ke Za Zhi; 2008 Jan 1;46(1):58-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prevention of facial nerve injury in acoustic neuroma microsurgery].
  • OBJECTIVE: To summarize and analyse the techniques of avoiding facial nerve injury during acoustic neuroma microsurgery.
  • METHODS: One hundred and eighty patients with large acoustic neuroma (> or =4 cm) and 70 patients with medium acoustic neuroma (2.4-4.0 cm) were diagnosed by MRI/ CT scan before operation and confirmed by postoperative pathologic examination.
  • All of patients were treated by sub-occipital retrosigmoid approach for tumor removal and facial nerve reservation during operation.
  • The relationships among the bone, arachnoid, nerve and vascular anatomy were particularly observed during the operation.
  • After decompression of the tumor, the origination and location of the facial nerve as well as the relationship between the tumor and the facial nerve should be identified.
  • The patients were followed-up from 6 months to 1 year postoperatively and assessed by House-Brackmann facial nerve function grading system.
  • RESULTS: Total tumor resection was achieved in 240 of 250 cases (96%) and subtotal in 10 cases including 1 case died because of cerebellar encephalomalacia after operation.
  • According to the House-Brackmann facial nerve function grading, recovery of normal function (grade I) was achieved in 214 cases (85.6%), grade II in 25 cases (10%), grade III in 5 cases (2.09%) and grade IV in 5 cases (2.09%).
  • CONCLUSION: Microneurosurgical techniques are helpful for total resection of acoustic neuroma and keeping facial nerve anatomic intact.
  • [MeSH-major] Facial Nerve Injuries / prevention & control. Intraoperative Complications / prevention & control. Microsurgery / methods. Neuroma, Acoustic / surgery

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  • (PMID = 18510007.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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74. Wiet RJ, Kazan RP, Ciric I, Littlefield PD: Acoustic neuroma (vestibular schwannoma) revision. Otolaryngol Clin North Am; 2006 Aug;39(4):751-62, vii
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acoustic neuroma (vestibular schwannoma) revision.
  • The authors present their experience of more than 25 years, now in excess of 1200 patients, with cerebellopontine angle tumors.
  • This article focuses on the management of planned subtotal resection of acoustic tumors in five subjects, and unexpected "residual" discovered by MRI scanning in 10 cases, which represents, to the best of the authors' knowledge, a residual rate of 1% of operated patients.
  • The rate of residual tumor is as high as 19% in some series and, in part, depends on the surgical approach.
  • For the purpose of this article, the authors did not include their cases of neurofibromatosis, because these tumors behave differently than unilateral sporadic schwannomas.
  • [MeSH-major] Neuroma, Acoustic / surgery
  • [MeSH-minor] Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm, Residual. Reoperation. Retrospective Studies. Time Factors. Treatment Outcome

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  • (PMID = 16895783.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Naguib MB, Cokkeser Y, Sanna M: Management of acoustic neuroma in the only hearing ear. Eur Arch Otorhinolaryngol; 2005 Feb;262(2):127-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of acoustic neuroma in the only hearing ear.
  • Patients with acoustic neuroma in their only hearing ear are not frequently seen in clinical practice.
  • In this study we report on five cases of acoustic neuroma in an only hearing ear.
  • Our decision for conservative management of those patients with regular follow-up using auditory brain stem response and magnetic resonance imaging is discussed.
  • [MeSH-major] Ear Neoplasms / complications. Ear Neoplasms / surgery. Hearing Loss, Unilateral / complications. Neuroma, Acoustic / complications. Neuroma, Acoustic / surgery

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  • (PMID = 15747105.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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76. Day AS, Wang CT, Chen CN, Young YH: Correlating the cochleovestibular deficits with tumor size of acoustic neuroma. Acta Otolaryngol; 2008 Jul;128(7):756-60
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  • [Title] Correlating the cochleovestibular deficits with tumor size of acoustic neuroma.
  • CONCLUSION: The tumor size of acoustic neuroma correlates with cochleovestibular deficits.
  • Those tumors with global frequency hearing loss, bilateral gaze nystagmus, or absent caloric and VEMP responses may indicate a tumor size >2.5 cm.
  • OBJECTIVE: This study aimed to investigate the correlation between cochleovestibular deficits and the size of acoustic neuroma.
  • PATIENTS AND METHODS: A total of 44 patients with acoustic neuroma were enrolled in this study.
  • Pure tone audiometry, electronystagmography, caloric test, vestibular evoked myogenic potential (VEMP) test, and MRI were conducted.
  • RESULTS: There is a trend of correlation between tumor size and audiographic configuration, with small-sized tumor in normal and rising types, medium-sized tumor in mid- and high-frequency hearing loss, and large-sized tumor in flat and deafness types.
  • Five patients with bilateral gaze nystagmus had significantly larger tumor size than those without nystagmus.
  • When 1 and 0 are used to represent abnormal and normal responses, respectively, the relationship between tumor size and vestibular function can be expressed as: tumor size (cm)=1.43 (caloric response)+1.35 (VEMP response), indicating that the estimated tumor size for those with abnormal caloric or VEMP responses increased by 1.43 or 1.35 cm, respectively.
  • [MeSH-major] Cochlea / physiopathology. Hearing Loss / physiopathology. Neuroma, Acoustic / physiopathology. Ocular Motility Disorders / physiopathology. Vestibule, Labyrinth / physiopathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Audiometry. Diagnosis, Differential. Electronystagmography. Evoked Potentials. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Nystagmus, Optokinetic. Prognosis. Severity of Illness Index. Vestibular Function Tests

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  • (PMID = 18568517.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
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77. Forssén UM, Lönn S, Ahlbom A, Savitz DA, Feychting M: Occupational magnetic field exposure and the risk of acoustic neuroma. Am J Ind Med; 2006 Feb;49(2):112-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Occupational magnetic field exposure and the risk of acoustic neuroma.
  • BACKGROUND: Acoustic neuroma is the intracranial tumor subtype showing the highest relative risk in relation to ionizing radiation but other environmental risk factors are largely unknown.
  • CONCLUSION: This study is the largest ever on acoustic neuroma and the first study to evaluate this tumor subtype specifically in relation to extremely low frequency magnetic fields.
  • The results do not support the hypothesis that 50 Hz magnetic fields increase the risk of acoustic neuroma.
  • [MeSH-major] Electromagnetic Fields / adverse effects. Neuroma, Acoustic / epidemiology. Occupational Exposure / adverse effects


78. Hours M, Bernard M, Arslan M, Montestrucq L, Richardson L, Deltour I, Cardis E: Can loud noise cause acoustic neuroma? Analysis of the INTERPHONE study in France. Occup Environ Med; 2009 Jul;66(7):480-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Can loud noise cause acoustic neuroma? Analysis of the INTERPHONE study in France.
  • OBJECTIVES: To investigate possible associations between risk of acoustic neuroma and exposure to loud noise in leisure and occupational settings.
  • The cases were the 108 subjects diagnosed with acoustic neuroma between 1 June 2000 and 31 August 2003.
  • RESULTS: Acoustic neuroma was found to be associated with loud noise exposure (odds ratio (OR) = 2.55; 95% CI 1.35 to 4.82), both in leisure settings, particularly when listening to loud music (OR = 3.88; 95% CI 1.48 to 10.17) and at work (OR = 2.26; 95% CI 1.08 to 4.72).
  • CONCLUSION: The present results agree with other recent reports implicating loud noise in the risk of acoustic neuroma.
  • [MeSH-major] Environmental Exposure / adverse effects. Neuroma, Acoustic / etiology. Noise / adverse effects

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  • (PMID = 19289391.001).
  • [ISSN] 1470-7926
  • [Journal-full-title] Occupational and environmental medicine
  • [ISO-abbreviation] Occup Environ Med
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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79. Edwards CG, Schwartzbaum JA, Nise G, Forssén UM, Ahlbom A, Lönn S, Feychting M: Occupational noise exposure and risk of acoustic neuroma. Am J Epidemiol; 2007 Dec 1;166(11):1252-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Occupational noise exposure and risk of acoustic neuroma.
  • A small number of prior epidemiologic studies of occupational noise exposure based on self-report have suggested an association with acoustic neuroma.
  • The goal of the present study was to further examine the association between noise exposure and acoustic neuroma by using an objective measure of exposure in the form of a job exposure matrix.
  • A total of 793 acoustic neuroma cases aged 21-84 years were identified between 1987 and 1999 from the Swedish Cancer Registry.
  • Contrary to previous study results, the present findings did not demonstrate an increased acoustic neuroma risk related to occupational noise exposure even after allowing for a long latency period.
  • [MeSH-major] Neuroma, Acoustic / etiology. Noise, Occupational / adverse effects. Occupational Exposure / adverse effects

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  • (PMID = 17804860.001).
  • [ISSN] 1476-6256
  • [Journal-full-title] American journal of epidemiology
  • [ISO-abbreviation] Am. J. Epidemiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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80. Takebayashi T, Akiba S, Kikuchi Y, Taki M, Wake K, Watanabe S, Yamaguchi N: Mobile phone use and acoustic neuroma risk in Japan. Occup Environ Med; 2006 Dec;63(12):802-7
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  • [Title] Mobile phone use and acoustic neuroma risk in Japan.
  • To examine the relation between mobile phone use and acoustic neuroma, a case-control study was initiated.
  • One hundred and one acoustic neuroma cases, who were 30-69 years of age and resided in the Tokyo area, and 339 age, sex, and residency matched controls were interviewed using a common computer assisted personal interview system.
  • RESULTS: Fifty one cases (52.6%) and 192 controls (58.2%) were regular mobile phone users on the reference date, which was set as one year before the diagnosis, and no significant increase of acoustic neuroma risk was observed, with the odds ratio (OR) being 0.73 (95% CI 0.43 to 1.23).
  • No exposure related increase in the risk of acoustic neuroma was observed when the cumulative length of use (<4 years, 4-8 years, >8 years) or cumulative call time (<300 hours, 300-900 hours, >900 hours) was used as an exposure index.
  • CONCLUSIONS: These results suggest that there is no significant increase in the risk of acoustic neuroma in association with mobile phone use in Japan.
  • [MeSH-major] Cell Phones. Neoplasms, Radiation-Induced / etiology. Neuroma, Acoustic / etiology

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  • (PMID = 16912083.001).
  • [ISSN] 1470-7926
  • [Journal-full-title] Occupational and environmental medicine
  • [ISO-abbreviation] Occup Environ Med
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2078004
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81. Nascentes SM, Paulo EA, de Andrade EC, da Silva AL, Vassoler TM, Scanavini AB: Sudden deafness as a presenting symptom of acoustic neuroma: case report. Braz J Otorhinolaryngol; 2007 Sep-Oct;73(5):713-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sudden deafness as a presenting symptom of acoustic neuroma: case report.
  • Vestibular schwannoma, also known as acoustic neurinoma, is the most frequent tumor of the cerebellopontine angle, and represents 9% of all intracranial tumors.
  • The patients responded to therapy with Prednisone and Pentoxifylline after the diagnosis of acoustic neurinoma by imaging exams.
  • [MeSH-major] Deafness / etiology. Neuroma, Acoustic / complications. Tinnitus / etiology


82. Minovi A, Mangold R, Kollert M, Hofmann E, Draf W, Bockmühl U: [Functional results, cognitive and effective quality of life disturbances after trans-temporal resection of acoustic neuroma]. Laryngorhinootologie; 2005 Dec;84(12):915-20
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  • [Title] [Functional results, cognitive and effective quality of life disturbances after trans-temporal resection of acoustic neuroma].
  • BACKGROUND: The aim of the study was to evaluate postoperative hearing, facial nerve function, quality of life (QOL), affective status and neuropsychological performance after trans-temporal removal of acoustic neuromas (AN).
  • One year postoperatively facial nerve function was excellent in 93.3 % of the patients (grade I and II).
  • However, facial nerve dysfunction did not lead to QOL effect.
  • [MeSH-major] Cognition Disorders / etiology. Deafness / etiology. Facial Paralysis / etiology. Neuroma, Acoustic / surgery. Postoperative Complications / etiology. Quality of Life / psychology. Temporal Lobe / surgery
  • [MeSH-minor] Adult. Aged. Depressive Disorder / etiology. Depressive Disorder / psychology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Reoperation

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  • (PMID = 16358202.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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83. Dizdarević K, Link MJ: [Operative treatment of the vestibular schwannoma (acoustic neuroma): correlation between the microsurgical approach and cranial nerve lesion]. Med Arh; 2005;59(3):160-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Operative treatment of the vestibular schwannoma (acoustic neuroma): correlation between the microsurgical approach and cranial nerve lesion].
  • [Transliterated title] Schwannoma vestibulare (neurinoma acustici)--operativni tretman: korelacija izmedu vrste mikroneurohirurskog pristupa i lezije kranijalnih nerava.
  • INTRODUCTION: Vestibular schwannoma (VS) is a benign tumour of cerebellopontine angle which total microsurgical resection is considered as a complex surgery.
  • Through analyzed series of operated patients (MJLink), we evaluated the correlation of VII and VIII nerves postoperative lesion with different operative approaches.
  • House-Brackmann grading scale is used for VII nerve deficit appraisal.
  • However, the most frequently used microsurgical approaches (retrosigmoid, translabyrinthine and extradural subtemporal) are still connected with certain morbidity rate, especially regarding the postoperative VII and VIII nerves lesion.
  • [MeSH-major] Microsurgery. Neuroma, Acoustic / surgery. Vestibulocochlear Nerve Injuries
  • [MeSH-minor] Facial Nerve Injuries / etiology. Humans. Intraoperative Complications


84. Parietti-Winkler C, Gauchard GC, Simon C, Perrin PP: Sensorimotor postural rearrangement after unilateral vestibular deafferentation in patients with acoustic neuroma. Neurosci Res; 2006 Jun;55(2):171-81
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  • [Title] Sensorimotor postural rearrangement after unilateral vestibular deafferentation in patients with acoustic neuroma.
  • Unilateral vestibular lesion, as acoustic neuroma and its surgical removal, leads to impaired balance control.
  • After initial vertigo and postural instability corresponding to unilateral vestibular deafferentation, improvement in symptoms and global balance functions occurs by a process called vestibular compensation.
  • In this respect, this prospective study aimed to assess the differential contribution of sensory inputs to the regulation of posture during the recovery process after acoustic neuroma removal.
  • Twenty-seven patients with acoustic neuroma underwent vestibular and posturographic testings, shortly before and 8 days, 1 month and 3 months after surgical removal of the tumour.
  • Immediately after vestibular deafferentation, vestibular function was asymmetrical, postural performances were altered, especially in eyes closed conditions and in sensory challenged situations.
  • One month, and more particularly 3 months after surgery, restoration and even improvement of vestibular and balance performances occurred, associated with a lower number of falls, development of more appropriate sensorimotor strategies and better resolution of sensorial conflicts.
  • Postural perturbations are related to erroneous vestibular afferences, leading to incoherence in information about head position and interference with somatosensory and visual pathways.
  • [MeSH-major] Denervation. Neuroma, Acoustic / surgery. Postural Balance / physiology. Posture / physiology. Vestibule, Labyrinth / innervation
  • [MeSH-minor] Adult. Analysis of Variance. Female. Functional Laterality. Humans. Male. Middle Aged. Nonlinear Dynamics. Otologic Surgical Procedures / methods. Prospective Studies. Vestibular Function Tests

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  • (PMID = 16621077.001).
  • [ISSN] 0168-0102
  • [Journal-full-title] Neuroscience research
  • [ISO-abbreviation] Neurosci. Res.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Ireland
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85. Hamann C, Rudolf J, von Specht H, Freigang B: [Vestibular evoked muscle potentials dependency on neural origin and the location of an acoustic neuroma]. HNO; 2005 Aug;53(8):690-4
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  • [Title] [Vestibular evoked muscle potentials dependency on neural origin and the location of an acoustic neuroma].
  • INTRODUCTION: Most acoustic neuromas (AN) originate from the inferior vestibular nerve (IVN).
  • Vestibular evoked myogenic potentials (VEMP) are accepted as the only unilateral test for the function of the sacculus and the IVN.
  • METHODS: The influence of the origin from the IVN and superior vestibular nerve (SVN), and the position of the AN in relation to the internal auditory canal on VEMPs was investigated.
  • [MeSH-major] Acoustic Stimulation / methods. Evoked Potentials, Auditory. Neuroma, Acoustic / diagnosis. Vestibular Function Tests / methods. Vestibulocochlear Nerve Diseases / diagnosis

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  • (PMID = 15558221.001).
  • [ISSN] 0017-6192
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Germany
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86. Brooker JE, Fletcher JM, Dally MJ, Briggs RJ, Cousins VC, Smee RI, Malham GM, Kennedy RJ, Burney S: Quality of life among acoustic neuroma patients managed by microsurgery, radiation, or observation. Otol Neurotol; 2010 Aug;31(6):977-84
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  • [Title] Quality of life among acoustic neuroma patients managed by microsurgery, radiation, or observation.
  • OBJECTIVE: The main aim of this study was to examine differences in quality of life (QoL) among acoustic neuroma patients across the management options of microsurgery, radiation, and observation.
  • PATIENTS: Participants included 180 adults diagnosed with, or treated for, a unilateral acoustic neuroma within 5 years of questionnaire distribution.
  • INTERVENTION(S): Patients' acoustic neuromas were managed with microsurgery, radiation, or observation.
  • CONCLUSION: This is only the second study to use multivariate statistical techniques and a large sample to examine QoL across the acoustic neuroma management options of microsurgery, radiation, and observation.
  • [MeSH-major] Cranial Nerve Neoplasms / psychology. Neuroma, Acoustic / psychology. Otologic Surgical Procedures. Quality of Life
  • [MeSH-minor] Adult. Aged. Disease Progression. Female. Glasgow Outcome Scale. Humans. Logistic Models. Male. Microsurgery. Middle Aged. Surveys and Questionnaires. Treatment Outcome. Young Adult

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  • (PMID = 20601919.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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87. Mazzoni A, Dubey SP, Poletti AM, Colombo G: Sporadic acoustic neuroma in pediatric patients. Int J Pediatr Otorhinolaryngol; 2007 Oct;71(10):1569-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sporadic acoustic neuroma in pediatric patients.
  • OBJECTIVE: Sporadic acoustic neuroma, usually occur between the ages of 40 and 70 years, are very rare in children.
  • We review the experiences of 10 cases of sporadic (non-NF2) acoustic neuromas in pediatric patients.
  • Among these almost 900 cases were acoustic neuromas.
  • The diameter of the tumors varied widely with minimum of 10 mm to maximum up to 60 mm.
  • Five patients each underwent resection of the tumor by translabyrinthine and retrosigmoid approach, respectively.
  • Postoperatively seven cases the facial nerve recovered to grade I, and one each to grade II and grade VI of House-Brackmann classification.
  • The youngest patient with largest tumor diameter of 60 mm developed transient hemiparesis in the immediate postoperative period and he recovered fully in due course.
  • CONCLUSION: We found preservation of facial nerve function is more easier than hearing in this group of patients.
  • [MeSH-major] Neuroma, Acoustic / epidemiology

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  • (PMID = 17643497.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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88. Bartoszewicz R, Niemczyk K, Marchel A, Kowalska M: [Sudden deafness as a presentation of acoustic neuroma]. Pol Merkur Lekarski; 2005 Sep;19(111):307-8
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  • [Title] [Sudden deafness as a presentation of acoustic neuroma].
  • [Transliterated title] Nagła głuchota w symptomatologii guzów nerwu VIII.
  • Acoustic neuroma should always be considered in the differential diagnosis.
  • The authors analysed symptoms occurring in the group of 89 patients, diagnosed with acoustic neuroma.
  • A special attention was paid to the role of sudden deafness as a clinical manifestation of the VIIIth nerve pathology.
  • [MeSH-major] Deafness / etiology. Headache / etiology. Hearing Loss, Sensorineural / etiology. Neuroma, Acoustic / complications. Neuroma, Acoustic / diagnosis. Tinnitus / etiology


89. Jalloh I, Guilfoyle MR, Lloyd SK, Macfarlane R, Smith C: Reactivation and centripetal spread of herpes simplex virus complicating acoustic neuroma resection. Surg Neurol; 2009 Nov;72(5):502-4
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  • [Title] Reactivation and centripetal spread of herpes simplex virus complicating acoustic neuroma resection.
  • CASE DESCRIPTION: A 44-year-old man underwent uneventful resection of an acoustic neuroma.
  • [MeSH-major] Encephalitis, Herpes Simplex / etiology. Facial Nerve Diseases / complications. Neuroma, Acoustic / complications. Neuroma, Acoustic / surgery. Neurosurgical Procedures / adverse effects. Simplexvirus / genetics
  • [MeSH-minor] Acyclovir / therapeutic use. Adult. Antiviral Agents / therapeutic use. Consciousness Disorders / virology. DNA, Viral / analysis. Facial Nerve / surgery. Facial Nerve / virology. Fever / virology. Humans. Magnetic Resonance Imaging. Male. Recurrence. Tomography, X-Ray Computed. Vestibulocochlear Nerve / pathology. Vestibulocochlear Nerve / radiography. Vestibulocochlear Nerve / surgery. Vomiting / virology

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  • (PMID = 19631366.001).
  • [ISSN] 1879-3339
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antiviral Agents; 0 / DNA, Viral; X4HES1O11F / Acyclovir
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90. Xue B, Yang J: [The characteristics of VEMP in patients with acoustic neuroma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Jan;22(1):22-5
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  • [Title] [The characteristics of VEMP in patients with acoustic neuroma].
  • OBJECTIVE: To establish the normal value of the vestibular evoked myogenic potential (VEMP), and to determine the characteristics of VEMP in patients with acoustic neuroma (AN) and to explore the significance of VEMP in diagnosis of AN.
  • VEMP was investigated in 14 patients with AN who underwent surgery during the period of 2006-2007 as well as auditory brainstem response (ABR) and vestibular caloric test.
  • [MeSH-major] Evoked Potentials, Auditory. Neuroma, Acoustic / physiopathology
  • [MeSH-minor] Acoustic Stimulation. Adult. Case-Control Studies. Electromyography. Female. Humans. Male. Middle Aged. Vestibular Function Tests. Young Adult

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  • (PMID = 18338565.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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91. Wackym PA: Stereotactic radiosurgery, microsurgery, and expectant management of acoustic neuroma: basis for informed consent. Otolaryngol Clin North Am; 2005 Aug;38(4):653-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stereotactic radiosurgery, microsurgery, and expectant management of acoustic neuroma: basis for informed consent.
  • Stereotactic radio-surgery, like any other treatment modality, has advantages and disadvantages that must be discussed with a patient who has an acoustic neuroma or other skull base tumor.
  • [MeSH-major] Neuroma, Acoustic / surgery. Otorhinolaryngologic Surgical Procedures. Radiosurgery

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  • (PMID = 16005724.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 36
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92. Tlachacova D, Schmitt M, Novotny J Jr, Novotny J, Majali M, Liscak R: A comparison of the gamma knife model C and the Automatic Positioning System with Leksell model B. J Neurosurg; 2005 Jan;102(s_supplement):25-28
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  • Data were analyzed in patients in whom the following diagnoses had been made: vestibular schwannoma, pituitary adenoma, meningioma, solitary metastasis, and other benign and malignant solitary tumors.
  • CONCLUSIONS: With the C model there was a better conformity for most treated targets, such as vestibular schwannomas (p = 0.005) and meningiomas (p = 0.015).

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  • (PMID = 28306471.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; conformity index / extracranial exposure / staff exposure / stereotactic radiosurgery
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93. Kalogeridi MA, Georgolopoulou P, Kouloulias V, Kouvaris J, Pissakas G: Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: the Greek experience. J Cancer Res Ther; 2009 Jan-Mar;5(1):8-13
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  • [Title] Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: the Greek experience.
  • PURPOSE: To estimate the value of LINAC-based stereotactic radiosurgery (SRS) for the long-term local control of unilateral acoustic neuromas.
  • MATERIALS AND METHODS: Twenty patients (median age 66; range 57-80 years) with unilateral acoustic neuroma underwent LINAC-based SRS from May 2000 through June 2004 with a dose of 11-12 Gy.
  • The follow-up consisted of repeat imaging studies and clinical examination for assessment of facial and trigeminal nerve function at 6-month intervals for the first year and yearly thereafter.
  • RESULTS: Eleven tumors (58%) decreased in size and eight (42%) remained stable.
  • One tumor showed a minor increase in size on the MRI done 6 months after SRS in comparison with the pretreatment MRI; however, a subsequent decrease was noticed on the next radiographic assessment and the tumor remained stable from then on.
  • None of the tumors increased in size in the long-term follow-up, thus giving an overall growth control of 100% for the patients in this study.
  • CONCLUSION: LINAC-based SRS with 11-12 Gy provides excellent tumor control in acoustic neuroma and has low toxicity even after long-term follow-up.
  • [MeSH-major] Neuroma, Acoustic / surgery. Radiosurgery

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  • (PMID = 19293482.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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94. Tufarelli D, Meli A, Alesii A, De Angelis E, Badaracco C, Falcioni M, Sanna M: Quality of life after acoustic neuroma surgery. Otol Neurotol; 2006 Apr;27(3):403-9
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  • [Title] Quality of life after acoustic neuroma surgery.
  • OBJECTIVE: The aim of this study is to assess patients' quality of life after acoustic neuroma surgery, and if some patients' characteristics, parameters of tumor and surgical parameters affect patients' quality of life.
  • PATIENTS: A group of 386 patients who underwent acoustic neuroma surgery.
  • INTERVENTION: Patients included were derived from a population of 459 subjects operated for acoustic neuroma by the Otologic Group of Piacenza.
  • Our data indicate that an early surgical approach for intrameatal tumor is better than waiting for an increase in the tumor size.
  • A "wait-and-scan" strategy for extrameatal neuromas which do not affect the brainstem is preferable, since these patients have a worsening of their quality of life after surgery independently of the tumor size.
  • [MeSH-major] Neuroma, Acoustic / surgery. Postoperative Complications / psychology. Quality of Life

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  • (PMID = 16639281.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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95. Saito AI, Morris CG, Ito K, Watanabe F, Karasawa K, Mendenhall WM, Naoi Y: Comparing size evaluation methods for acoustic neuroma after stereotactic radiosurgery. Radiat Med; 2007 Aug 1;25(7):339-45
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  • [Title] Comparing size evaluation methods for acoustic neuroma after stereotactic radiosurgery.
  • PURPOSE: Acoustic neuroma tumor size may be evaluated using several methods.
  • MATERIALS AND METHODS: A retrospective analysis of pre- and posttreatment magnetic resonance (MR) scans was performed on 15 acoustic neuroma patients with a history of stereotactic radiosurgery who had been followed for more than 2 years.
  • Tumor size was measured on each MR scan using three methods, where the extracanalicular (EX) and intracanalicular (IN) portions were measured separately.
  • Size differences between follow-up MR scans separated by more than 2 years were calculated for each method, and we evaluated whether the tumors progressed, remained stable, or regressed.
  • CONCLUSION: A significant difference between the tumor size measuring methods was observed.
  • To strengthen specificity when evaluating tumor size difference, a measuring method using two or more parameters is recommended.
  • [MeSH-major] Magnetic Resonance Imaging. Neuroma, Acoustic / pathology. Neuroma, Acoustic / surgery. Radiosurgery / methods
  • [MeSH-minor] Adult. Aged. Artifacts. Disease Progression. Female. Humans. Male. Middle Aged. Reproducibility of Results. Retrospective Studies. Stereotaxic Techniques. Treatment Outcome

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  • (PMID = 17705004.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
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96. Yu LM, Yang SM, Han DY, Yu LM, Yang WY: [Preliminary study of intraoperative auditory monitoring techniques in acoustic neuroma surgery]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2006 May;41(5):335-40
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  • [Title] [Preliminary study of intraoperative auditory monitoring techniques in acoustic neuroma surgery].
  • OBJECTIVE: To investigate the value of intraoperative auditory monitoring techniques in acoustic neuroma surgery.
  • METHODS: Ten cases with acoustic neuroma were resected with retrosigmoid approach.
  • The hearing was preserved in 2 cases, which had class A hearing post operation with tumor size <2 cm.
  • In another case, the waves of I, III could be evoked after the tumor resection with the disappearance of wave V.
  • The 6 out of 8 cases showed up CAP (waves I ) waveform.
  • The CAP amplitudes decreased significantly in 4 cases and even dropped to zero while dissecting the tumor at the lateral end of the internal auditory canal (IAC) or clamping the internal auditory artery (IAA) during operation.
  • In one case, although the cochlear nerve was cut down, the CAP could still be recorded after the tumor resection.
  • However, the CAP amplitudes was dropped to zero while pressurized and pulled cochlea nerve of brainstem lateral and the wave disappeared post-operation in another cases.
  • One of them showed low amplitude of CAP wave when the tumor partially removed.
  • CONCLUSIONS: In combination with ABR monitoring, ECochG proved to be a useful supplementary tool for hearing preservation in acoustic neurinoma surgery.
  • Drilling of the IAC and tumor removal at the lateral end of the IAC were the most critical steps for achieving hearing preservation.
  • The surgeon's experience are the most significant factors influencing the hearing outcome after removal of acoustic neuroma.
  • [MeSH-major] Cochlear Nerve / physiopathology. Monitoring, Intraoperative / methods. Neuroma, Acoustic / physiopathology
  • [MeSH-minor] Adolescent. Adult. Audiometry, Evoked Response. Evoked Potentials, Auditory, Brain Stem. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 16848284.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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97. Inoue HK: Low-dose radiosurgery for large vestibular schwannomas: long-term results of functional preservation. J Neurosurg; 2005 Jan;102(s_supplement):111-113

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low-dose radiosurgery for large vestibular schwannomas: long-term results of functional preservation.
  • OBJECT: The author conducted a study to assess the long-term results obtained in patients who underwent GKS for large vestibular schwannomas (> cochlear nerve functions were evaluated.
  • METHODS: Twenty consecutive large tumors in 18 patients (including two cases of neurofibromatosus Type 2 [NF2]) were followed for more than 6 years.
  • There were eight tumors that were more than 4 cm in maximum diameter.
  • Microsurgery had already been performed prior to GKS in 11 patients (nine recurrent and two residual tumors).
  • Fourteen of 15 tumors were stable or decreased in size.
  • Facial nerve function was preserved in all patients and hearing preserved in four of five patients with cochlear nerve function prior to radiosurgery.
  • CONCLUSIONS: Gamma knife surgery seems to have a place in the low-dose treatment of selected large vestibular schwannoma in patients with a reasonable chance of retaining facial function and pretreatment hearing level.

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  • (PMID = 28306427.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; facial function / gamma knife surgery / outcome / vestibular schwannoma
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98. Jaspers GW, Stegenga B: [Trigeminal neuralgia by an acoustic neuroma. The need of imaging]. Ned Tijdschr Tandheelkd; 2005 Jun;112(6):231-3
MedlinePlus Health Information. consumer health - Trigeminal Neuralgia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Trigeminal neuralgia by an acoustic neuroma. The need of imaging].
  • [Transliterated title] Trigeminusneuralgie door een neurinoom van de nervus acusticus. De noodzaak van beeldvormend onderzoek.
  • In a 43-year old female with neuralgia of the second and third branch of the trigeminal nerve, the diagnosis was made on the basis of clinical findings.
  • This investigation showed an acoustic neuroma in the cerebellopontine angle.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Neuroma, Acoustic / complications. Neuroma, Acoustic / diagnosis. Trigeminal Neuralgia / diagnosis. Trigeminal Neuralgia / etiology


99. del Río L, Lassaletta L, Alfonso C, Sarriá MJ, Gavilán J: [Clinical tumoral size dissociation in acoustic neuroma: reality or measure distortion?]. Acta Otorrinolaringol Esp; 2006 Oct;57(8):345-9
MedlinePlus Health Information. consumer health - Acoustic Neuroma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical tumoral size dissociation in acoustic neuroma: reality or measure distortion?].
  • [Transliterated title] Disociación clínica-tamaño tumoral en el neurinoma del acúistico: realidad o problema de medida?
  • INTRODUCTION: In this study we have analyzed (i) the audiometric frequencies more often affected in acoustic neuroma (AN), (ii) the percentage of patients presenting normal hearing and those with sudden hearing loss, (iii) if there is a correlation between tumor size and hearing loss, and (iv) the relationship between clinical and radiological parameters and audiological data.
  • RESULTS: The highest threshold in the tumor's ear was found at 8000 Hz, and the highest interaural difference at 4000 Hz.
  • No significant association was found between tumor size and hearing loss, preoperative facial palsy or Vth cranial nerve deficit.
  • There was a significant association between the degree of hearing loss and Vth cranial nerve deficit, and between hearing loss and preoperative facial palsy.
  • CONCLUSIONS: The association between hearing loss and Vth cranial nerve deficit, and between hearing loss and preoperative facial palsy is independent the size of the tumour.
  • [MeSH-major] Hearing Loss / etiology. Neuroma, Acoustic / complications. Neuroma, Acoustic / pathology

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  • (PMID = 17117690.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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100. Boisson-Bertrand D, Laxenaire MC, Mertes PM: Recovery after prolonged anaesthesia for acoustic neuroma surgery: desflurane versus isoflurane. Anaesth Intensive Care; 2006 Jun;34(3):338-42
Hazardous Substances Data Bank. Desflurane .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recovery after prolonged anaesthesia for acoustic neuroma surgery: desflurane versus isoflurane.
  • In this study, 33 patients were randomly assigned to receive desflurane (D) or isoflurane (I) for acoustic neuroma surgery.
  • The results indicate that desflurane is associated with similar operating conditions and faster postoperative recovery following acoustic neuroma surgery.
  • [MeSH-major] Anesthesia Recovery Period. Anesthesia, Inhalation. Anesthetics, Inhalation. Isoflurane / analogs & derivatives. Neuroma, Acoustic / surgery

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  • MedlinePlus Health Information. consumer health - Acoustic Neuroma.
  • Hazardous Substances Data Bank. Isoflurane .
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  • (PMID = 16802487.001).
  • [ISSN] 0310-057X
  • [Journal-full-title] Anaesthesia and intensive care
  • [ISO-abbreviation] Anaesth Intensive Care
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Anesthetics, Inhalation; CRS35BZ94Q / desflurane; CYS9AKD70P / Isoflurane
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