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36. Nalesso A, Viel G, Cecchetto G, Frison G, Ferrara SD: Analysis of the alcohol biomarker phosphatidylethanol by NACE with on-line ESI-MS. Electrophoresis; 2010 Apr;31(7):1227-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The effects of variable percentages of ACN, MeOH, 2-propanol, dichloromethane, along with variable concentrations of ammonium acetate were investigated for the separation of Peth.
  • Collectively, a separation medium composed of ACN (45% v/v), 2-propanol (20% v/v), dichloromethane (20% v/v), MeOH (10% v/v), water (5% v/v), and ammonium acetate (25 mM) was chosen.

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  • (PMID = 20196026.001).
  • [ISSN] 1522-2683
  • [Journal-full-title] Electrophoresis
  • [ISO-abbreviation] Electrophoresis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Acetonitriles; 0 / Biomarkers; 0 / Glycerophospholipids; 0 / phosphatidylethanol; Y4S76JWI15 / Methanol; Z072SB282N / acetonitrile
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37. Kodama S, Taga A, Yamamoto A, Ito Y, Honda Y, Suzuki K, Yamashita T, Kemmei T, Aizawa S: Enantioseparation of DL-isocitric acid by a chiral ligand exchange CE with Ni(II)-D-quinic acid system. Electrophoresis; 2010 Oct;31(21):3586-91
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  • The optimum running conditions for the analysis of D- and L-isocitric acids along with citric acid, an isomer of isocitric acid, were found to be a BGE (pH 5.0) containing 30% ACN, 20 mM acetic acid, 20 mM NiSO(4), and 80 mM D-quinic acid.

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  • (PMID = 20925051.001).
  • [ISSN] 1522-2683
  • [Journal-full-title] Electrophoresis
  • [ISO-abbreviation] Electrophoresis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Cation Exchange Resins; 0 / Cations, Divalent; 0 / Isocitrates; 058C04BGYI / Quinic Acid; 320-77-4 / isocitric acid; 7OV03QG267 / Nickel
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38. Biesaga M, Ochnik U, Pyrzynska K: Fast analysis of prominent flavonoids in tomato using a monolithic column and isocratic HPLC. J Sep Sci; 2009 Aug;32(15-16):2835-40
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  • The concentration of organic modifier (methanol and ACN) was tested in order to obtain the best resolution.

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  • (PMID = 19575378.001).
  • [ISSN] 1615-9314
  • [Journal-full-title] Journal of separation science
  • [ISO-abbreviation] J Sep Sci
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Flavanones; 0 / Flavonoids; 0 / Kaempferols; 0 / Plant Extracts; 5G06TVY3R7 / Rutin; 731P2LE49E / kaempferol; 76XC01FTOJ / myricetin; 9IKM0I5T1E / Quercetin; HN5425SBF2 / naringenin; N7TD9J649B / naringin; Y4S76JWI15 / Methanol
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39. Acosta GA, del Fresno M, Paradis-Bas M, Rigau-DeLlobet M, Côté S, Royo M, Albericio F: Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins. J Pept Sci; 2009 Oct;15(10):629-33
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  • This manuscript shows that ACN can be an excellent choice for the coupling of hindered amino acids as illustrated by the coupling of Fmoc-amino acids on free amino acids anchored on a BAL synthesis.
  • Furthermore, ACN can be a good alternative for solid-phase peptide synthesis in the absence of DMF (washings, removal of Fmoc, and coupling).

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  • [Copyright] 2009 European Peptide Society and John Wiley & Sons, Ltd.
  • (PMID = 19634177.001).
  • [ISSN] 1099-1387
  • [Journal-full-title] Journal of peptide science : an official publication of the European Peptide Society
  • [ISO-abbreviation] J. Pept. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Acetonitriles; 0 / Amino Acids; 0 / Fluorenes; 0 / N(alpha)-fluorenylmethyloxycarbonylamino acids; 0 / Peptides; 0 / Polystyrenes; 0 / Solvents; 0 / aminomethyl-ChemMatrix resin; 0 / polyethylene glycol-polystyrene; 30IQX730WE / Polyethylene Glycols; Z072SB282N / acetonitrile
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40. Feiden S, Sartorius E, Feiden W: [The role of diagnostic neuropathology in familial tumour syndromes]. Pathologe; 2010 Oct;31(6):464-70
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  • Furthermore, tumour location and patient age may point to a familial tumour syndrome as in the case of neurofibromatosis type 2 (NF2) with typical bilateral vestibular schwannoma in young age.
  • [MeSH-minor] Central Nervous System Neoplasms / genetics. Central Nervous System Neoplasms / pathology. Chromosome Mapping. Chromosomes, Human, Pair 16. Chromosomes, Human, Pair 17. Chromosomes, Human, Pair 22. Chromosomes, Human, Pair 9. Genes, Neurofibromatosis 1. Genes, Neurofibromatosis 2. Humans. Li-Fraumeni Syndrome / genetics. Li-Fraumeni Syndrome / pathology. Neurofibromatosis 1 / genetics. Neurofibromatosis 1 / pathology. Neurofibromatosis 2 / genetics. Neurofibromatosis 2 / pathology. Neuroma, Acoustic / genetics. Neuroma, Acoustic / pathology. Peripheral Nervous System Neoplasms / genetics. Peripheral Nervous System Neoplasms / pathology. Rhabdoid Tumor / genetics. Rhabdoid Tumor / pathology. Teratoma / genetics. Teratoma / pathology. Tuberous Sclerosis / genetics. Tuberous Sclerosis / pathology

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  • [Cites] Genet Med. 2010 Jan;12(1):1-11 [20027112.001]
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  • (PMID = 20848106.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
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71. Sarmento B, Ribeiro A, Veiga F, Ferreira D: Development and validation of a rapid reversed-phase HPLC method for the determination of insulin from nanoparticulate systems. Biomed Chromatogr; 2006 Sep;20(9):898-903
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  • A reversed-phase (RP) C18 column and gradient elution with a mobile phase composed of acetonitrile (ACN) and 0.1% aqueous trifluoroacetic acid (TFA) solution at a flow rate of 1 mL/min was used.
  • The gradient changed from 30:70 (ACN:TFA, v/v) to 40:60 (v/v) in 5 min followed by isocratic elution at 40:60 (v/v) for a further five minutes.

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  • [Copyright] Copyright 2006 John Wiley & Sons, Ltd.
  • (PMID = 16389645.001).
  • [ISSN] 0269-3879
  • [Journal-full-title] Biomedical chromatography : BMC
  • [ISO-abbreviation] Biomed. Chromatogr.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Insulin
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72. Xia Y: [Bilateral acoustic neuromas]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Mar;43(3):237-40
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  • [Title] [Bilateral acoustic neuromas].

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  • (PMID = 18630294.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Journal Article
  • [Publication-country] China
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73. Li Y, Luo Y, Wu S, Gao Y, Liu Y, Zheng D: Nucleic acids in protein samples interfere with phosphopeptide identification by immobilized-metal-ion affinity chromatography and mass spectrometry. Mol Biotechnol; 2009 Sep;43(1):59-66
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  • Acetonitrile (ACN) precipitation, a simple and efficient procedure, was established to remove nucleic acids from the protein samples.
  • We showed that ACN precipitation approximately doubled the phosphopeptide number identified by IMAC and mass spectrometry, indicating that nucleic acid removal significantly improves the identification of phosphopeptides.

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  • (PMID = 19412670.001).
  • [ISSN] 1073-6085
  • [Journal-full-title] Molecular biotechnology
  • [ISO-abbreviation] Mol. Biotechnol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Complex Mixtures; 0 / Metals; 0 / Nucleic Acids; 0 / Phosphopeptides; 0 / Proteins
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7
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4. Guan J, Yang J, Bi Y, Shi S, Yan F, Li F: Determination of the enantiomeric impurity in S-(-)pantoprazole using high performance liquid chromatography with sulfobutylether-beta-cyclodextrin as chiral additive. J Sep Sci; 2008 Feb;31(2):288-93
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  • The influences of type and concentration of CD, ACN content and buffer pH of mobile phase on the resolution and retention of enantiomers were investigated.
  • A baseline resolution of pantoprazole enantiomers was achieved on a Spherigel C18 column (150 mm x 4.6 mm, 5 microm) using ACN and 10 mM phosphate buffer (pH 2.5) containing 10 mM SBE-beta-CD (15:85 v/v) as mobile phase with a flow rate of 0.9 mL/min at 20 degrees C.

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  • (PMID = 18196525.001).
  • [ISSN] 1615-9306
  • [Journal-full-title] Journal of separation science
  • [ISO-abbreviation] J Sep Sci
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / 2-Pyridinylmethylsulfinylbenzimidazoles; 0 / Anti-Ulcer Agents; 0 / SBE4-beta-cyclodextrin; 0 / beta-Cyclodextrins; D8TST4O562 / pantoprazole
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75. Kokkonen M, Jestoi M: Determination of ergot alkaloids from grains with UPLC-MS/MS. J Sep Sci; 2010 Aug;33(15):2322-7
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  • The analytes were extracted from the sample matrix with ACN/ammonium carbonate solution.

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  • (PMID = 20572264.001).
  • [ISSN] 1615-9314
  • [Journal-full-title] Journal of separation science
  • [ISO-abbreviation] J Sep Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ergot Alkaloids
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91. Beaudry F, Ferland CE, Vachon P: Identification, characterization and quantification of specific neuropeptides in rat spinal cord by liquid chromatography electrospray quadrupole ion trap mass spectrometry. Biomed Chromatogr; 2009 Sep;23(9):940-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Samples were chromatographed using a microbore C(8) 100 x 1 mm column and a 19 min linear gradient (0:100 --> 40:60; ACN:0.2% formic acid in water) at a flow rate of 75 microL/min for a total run time of 32 min.

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  • [Copyright] Copyright (c) 2009 John Wiley & Sons, Ltd.
  • (PMID = 19358311.001).
  • [ISSN] 1099-0801
  • [Journal-full-title] Biomedical chromatography : BMC
  • [ISO-abbreviation] Biomed. Chromatogr.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neuropeptides; 33507-63-0 / Substance P; 74913-18-1 / Dynorphins; 83652-28-2 / Calcitonin Gene-Related Peptide
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92. Jamróz B, Lachowska M, Niemczyk K, Morawski K, Bartoszewicz R, Pierchała K: [Possibility of hearing preservation treatment by patient suffered from neurofibromatosis type 2: case report]. Otolaryngol Pol; 2010 Mar-Apr;64(2):114-7
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  • The main tumor of cerebellopontine angle are vestibular schwannoma (80-90%).
  • Most of them are unilateral lesion but 5% of them are bilateral pathological mass.
  • The aim of the study is case report of the patient suffered from bilateral vestibular schwannoma.
  • [MeSH-major] Cochlear Implantation / methods. Cranial Nerve Neoplasms / surgery. Hearing Loss, Bilateral / prevention & control. Neurofibromatosis 2 / surgery

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  • (PMID = 20568541.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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93. Chung WC, Tso SC, Sze ST: Separation of polar mushroom toxins by mixed-mode hydrophilic and ionic interaction liquid chromatography-electrospray ionization-mass spectrometry. J Chromatogr Sci; 2007 Feb;45(2):104-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • At a high acetonitrile (ACN) concentration, hydrophilic interaction dominates, and all analytes under study demonstrate a much higher affinity with the stationary phase.
  • Valley-to-valley separation is achieved upon the optimatizatiqn of the mobile phase (comprising of ACN, MeOH, and ammonium formate buffer at pH approximately 3.5) and the solvent gradient.

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  • (PMID = 17425140.001).
  • [ISSN] 0021-9665
  • [Journal-full-title] Journal of chromatographic science
  • [ISO-abbreviation] J Chromatogr Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Buffers; 0 / Salts; 0 / Toxins, Biological
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94. Gritti F, Guiochon G: The adsorption mechanism of nortryptiline on C18-bonded Discovery. J Chromatogr A; 2005 Nov 18;1095(1-2):27-39
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  • The adsorption isotherms of an ionizable compound, nortriptyline, were accurately measured by frontal analysis (FA) on a C(18)-Discovery column, first without buffer (in an aqueous solution of acetonitrile at 15%, v/v of ACN), then with a buffer (in 28%, v/v ACN solution).

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  • (PMID = 16275280.001).
  • [ISSN] 0021-9673
  • [Journal-full-title] Journal of chromatography. A
  • [ISO-abbreviation] J Chromatogr A
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Acetonitriles; 0 / Buffers; 0 / Formates; 0 / Phosphates; 64-18-6 / formic acid; BL03SY4LXB / Nortriptyline; Z072SB282N / acetonitrile
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95. Viñas P, Aguinaga N, Campillo N, Hernández-Córdoba M: Comparison of stir bar sorptive extraction and membrane-assisted solvent extraction for the ultra-performance liquid chromatographic determination of oxazole fungicide residues in wines and juices. J Chromatogr A; 2008 Jun 20;1194(2):178-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The analytes were separated on a rapid resolution C(18) column (50 mm x 4.6 mm, I.D., 1.8 microm) thermostated at 50 degrees C with isocratic elution using a 50/50 (v/v) water/acetonitrile (ACN) mobile phase at a flow-rate of 1 mL min(-1) and detected by diode-array detection (DAD).
  • Liquid desorption was performed with 100 microL of a 80/20 (v/v) ACN/water solution in a desorption time of 15 min.

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  • (PMID = 18471821.001).
  • [ISSN] 0021-9673
  • [Journal-full-title] Journal of chromatography. A
  • [ISO-abbreviation] J Chromatogr A
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Fungicides, Industrial; 0 / Oxazoles
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96. Alves de Almeida A, Scarminio IS: Statistical mixture design optimization of extraction media and mobile phase compositions for the characterization of green tea. J Sep Sci; 2007 Feb;30(3):414-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The optimum compositions of solvent to extract chemical substances from green tea and for mobile phase chromatographic analysis were ethyl acetate/ ethanol/dichloromethane (20:5:75 v/v/v) and MeOH/ACN/water (7.5:57.5:35 v/v/v), respectively.

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  • (PMID = 17396601.001).
  • [ISSN] 1615-9306
  • [Journal-full-title] Journal of separation science
  • [ISO-abbreviation] J Sep Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Plant Extracts; 0 / Solvents; 0 / Tea
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97. Sämann PG, Tully C, Spoormaker VI, Wetter TC, Holsboer F, Wehrle R, Czisch M: Increased sleep pressure reduces resting state functional connectivity. MAGMA; 2010 Dec;23(5-6):375-89
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among the spontaneously fluctuating resting state networks, the default mode network (DMN) and its anticorrelated network (ACN) hold key functions in segregating internally and externally directed awareness.
  • We used independent component and cross-correlation analysis to study functional connectivity (fc), focusing on the DMN and ACN.
  • RESULTS: After PSD, focal reductions of auto-correlation strength were detected in the posterior and anterior midline node of the DMN and in the lateral parietal and insular nodes of the ACN.
  • Cross-correlation analysis confirmed reduced cortico-cortical connectivity within and between the DMN and ACN.
  • CONCLUSIONS: Increased sleep pressure is reflected in reduced fc of main DMN and ACN nodes during rest.

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  • (PMID = 20473549.001).
  • [ISSN] 1352-8661
  • [Journal-full-title] Magma (New York, N.Y.)
  • [ISO-abbreviation] MAGMA
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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98. Tadesse M, Gulliksen B, Strøm MB, Styrvold OB, Haug T: Screening for antibacterial and antifungal activities in marine benthic invertebrates from northern Norway. J Invertebr Pathol; 2008 Nov;99(3):286-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lyophilized material from seven species of ascidians, six sponges and one soft alcyonid coral were extracted with 60% acidified acetonitrile (ACN).
  • After separation into an ACN-rich phase (ACN-extract) and an aqueous phase, and subsequent solid-phase extraction of the aqueous phase, fractions differing in polarity were obtained and screened for antibacterial and antifungal activities, along with the more lipophilic ACN-extracts.

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  • (PMID = 18621054.001).
  • [ISSN] 1096-0805
  • [Journal-full-title] Journal of invertebrate pathology
  • [ISO-abbreviation] J. Invertebr. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Antifungal Agents; 0 / Tissue Extracts
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99. Jiao ZQ, Guo YC, Xu Y: [The effects of acrylonitrile on cell apoptosis, proliferation and related genes expression of rat normal and tumor glial cells]. Zhonghua Yu Fang Yi Xue Za Zhi; 2008 Jun;42(6):405-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To study the effect of acrylonitrile (ACN) to cell growth, apoptosis, proliferation and related gene expression of rat normal glial cells (DI TNC1) and tumor glial cells (C6).
  • METHODS: The concentration of ACN on DI TNC1 and C6 were 25, 50 and 75 microg/ml.
  • RESULTS: After treatment of DI TNC1 cell with 25,50 and 75 microg/ml ACN, the DNA synthesis index were decreased 93.1%, 81.3% and 74.9% as compared to control respectively, the apoptosis index was increased 118%, 122% and 143% as compared to controls respectively.
  • The DNA synthesis and apoptosis indexes of C6 cell showed no change after treatment with ACN.
  • The cell cycle and apoptosis pathway related genes, such as cyclin and p53, also showed changes after treatment with ACN.
  • CONCLUSION: ACN inhibited the cell proliferation of DI TNC1, induced the apoptosis of DI TNC1 and had no effect on cell proliferation and apoptosis of C6 cells, and the related regulation gene expression changes further confirmed the results.

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  • (PMID = 19035041.001).
  • [ISSN] 0253-9624
  • [Journal-full-title] Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
  • [ISO-abbreviation] Zhonghua Yu Fang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Air Pollutants; MP1U0D42PE / Acrylonitrile
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100. Nabetani T, Kim YJ, Watanabe M, Ohashi Y, Kamiguchi H, Hirabayashi Y: Improved method of phosphopeptides enrichment using biphasic phosphate-binding tag/C18 tip for versatile analysis of phosphorylation dynamics. Proteomics; 2009 Dec;9(24):5525-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The improvement in selectivity for phosphopeptides was achieved by using a 40% ACN solution under the phosphopeptides binding conditions.

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  • (PMID = 19834909.001).
  • [ISSN] 1615-9861
  • [Journal-full-title] Proteomics
  • [ISO-abbreviation] Proteomics
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Phosphopeptides; 0 / Proteome; 0 / Tumor Necrosis Factor-alpha
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