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Items 1 to 61 of about 61
1. Vidyadhara S, Shetty AP, Rajasekaran S: Widespread metastases from acinic cell carcinoma of parotid gland. Singapore Med J; 2007 Jan;48(1):e13-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Widespread metastases from acinic cell carcinoma of parotid gland.
  • Acinic cell carcinoma metastasising to the spine is rare and has been described only once before in the literature.
  • We believe this 40-year-old man to be the first reported case of incompletely resected acinic cell carcinoma of the parotid gland metastasising simultaneously to regional lymph nodes, upper lobes of both lungs, sphenoid bone and dorsal spine with neurological deficits.
  • [MeSH-major] Carcinoma, Acinar Cell / secondary. Lung Neoplasms / secondary. Parotid Neoplasms / pathology. Skull Neoplasms / secondary. Sphenoid Bone. Spinal Neoplasms / secondary. Thoracic Vertebrae

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  • (PMID = 17245497.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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2. Gomez DR, Katabi N, Zhung J, Wolden SL, Zelefsky MJ, Kraus DH, Shah JP, Wong RJ, Ghossein RA, Lee NY: Clinical and pathologic prognostic features in acinic cell carcinoma of the parotid gland. Cancer; 2009 May 15;115(10):2128-37
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  • [Title] Clinical and pathologic prognostic features in acinic cell carcinoma of the parotid gland.
  • BACKGROUND: To the authors' knowledge, the indications for adjuvant treatment in acinic cell carcinoma (AciCC) of the parotid gland have not been elucidated to date.
  • METHODS: Between March of 1989 and August of 2006, 35 patients underwent surgery at Memorial Sloan-Kettering Cancer Center for AciCC of the parotid gland and had their clinical and pathologic features retrospectively analyzed at the primary site.
  • [MeSH-major] Carcinoma, Acinar Cell / diagnosis. Parotid Neoplasms / diagnosis

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  • (PMID = 19309749.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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3. Al-Zaher N, Obeid A, Al-Salam S, Al-Kayyali BS: Acinic cell carcinoma of the salivary glands: a literature review. Hematol Oncol Stem Cell Ther; 2009;2(1):259-64
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  • [Title] Acinic cell carcinoma of the salivary glands: a literature review.
  • Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies.
  • In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.
  • A slowly enlarging mass lesion in the tail of the parotid gland is the most frequent presentation.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 20063555.001).
  • [ISSN] 1658-3876
  • [Journal-full-title] Hematology/oncology and stem cell therapy
  • [ISO-abbreviation] Hematol Oncol Stem Cell Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 59
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4. Moore FR, Bergman S, Geisinger KR: Metastatic hepatocellular carcinoma mimicking acinic cell carcinoma of the parotid gland: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):889-92
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  • [Title] Metastatic hepatocellular carcinoma mimicking acinic cell carcinoma of the parotid gland: a case report.
  • BACKGROUND: Fine needle aspiration (FNA) is becoming increasingly important in the diagnosis of salivary gland lesions.
  • We describe a case where a right cheek/parotid mass was originally diagnosed as acinic cell carcinoma (ACC) upon biopsy.
  • Later, an FNA resampling of the mass was diagnosed as hepatocellular carcinoma (HCC), and indeed, a subsequently performed computed tomography scan showed that the patient had a previously unknown liver mass.
  • The patient shortly thereafter developed an abdominal lesion that upon FNA was found to be cytologically similar to the parotid mass.
  • An FNA resampling of the parotid lesion was then performed, and stains showed that it was also Hep Par 1 positive.
  • CONCLUSION: A right cheek/parotid mass initially diagnosed as ACC was later found to be metastatic HCC.
  • At times, the judicious use of immunohistochemical stains is necessary to distinguish primary salivary gland neoplasias from metastatic tumors.
  • [MeSH-major] Carcinoma, Acinar Cell / diagnosis. Carcinoma, Hepatocellular / pathology. Liver Neoplasms / pathology. Parotid Gland / pathology. Parotid Neoplasms / diagnosis. Parotid Neoplasms / secondary

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  • (PMID = 21053563.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Greig SR, Chaplin JM, McIvor NP, Izzard ME, Taylor G, Wee D: Acinic cell carcinoma of the parotid gland: Auckland experience and literature review. ANZ J Surg; 2008 Sep;78(9):754-8
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  • [Title] Acinic cell carcinoma of the parotid gland: Auckland experience and literature review.
  • Acinic cell carcinoma is an uncommon malignancy of the salivary glands and as such it has been difficult to accurately delineate its natural history.
  • The aim of this study is to assess the behaviour of acinic cell salivary cancer of the parotid gland presenting to a single head and neck surgical unit in Auckland.
  • The study is a structured review of cases of acinic cell carcinoma of the parotid gland presenting from 2000 to 2006 to the Head and Neck Unit at Auckland Hospital, those identified from the pathology database and the Otobase head and neck database.
  • [MeSH-major] Parotid Neoplasms / pathology. Parotid Neoplasms / surgery

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  • (PMID = 18844902.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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6. Smukalla K, Kalinski T, Motsch C: [Distant metastases on acinic cell carcinoma of the parotid gland after 12 years symptom-free interval]. Laryngorhinootologie; 2006 Aug;85(8):586-8
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  • [Title] [Distant metastases on acinic cell carcinoma of the parotid gland after 12 years symptom-free interval].
  • Acinic cell carcinoma of parotid gland as cause of distant metastases are rare.
  • The patient was a 60-year-old woman who had in 1993 a acinic cell carcinoma of right parotid gland.
  • Histologically and immunohistochemically the diagnosis of distant metastase on acinic carcinoma of the parotid gland was confirmed.
  • [MeSH-major] Bone Neoplasms / secondary. Carcinoma, Acinar Cell / secondary. Manubrium. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Female. Follow-Up Studies. Humans. Middle Aged. Neck Dissection. Neoplasm Staging. Osteolysis / diagnosis. Osteolysis / pathology. Osteolysis / surgery. Parotid Gland / pathology. Parotid Gland / surgery. Radionuclide Imaging. Reoperation. Tomography, X-Ray Computed

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  • (PMID = 16883494.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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7. Piechocki MP, Dibbley SK, Lonardo F, Yoo GH: Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu. Int J Cancer; 2008 Apr 15;122(8):1722-9
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  • We observed a decrease in the number and size of lobules and lobular nodules in treated mice with a reduction in the overall disease burden per gland.
  • The development of acinic cell carcinoma in the parotid glands of these animals was also reduced coincident with decreased stromal involvement during progression.
  • [MeSH-minor] Administration, Oral. Animals. Carcinoma, Acinar Cell / drug therapy. Carcinoma, Acinar Cell / prevention & control. Carcinoma, Lobular / drug therapy. Carcinoma, Lobular / prevention & control. Disease Progression. Female. Gene Expression Regulation, Neoplastic. Mice. Mice, Inbred BALB C. Mice, Transgenic. Mitogen-Activated Protein Kinase Kinases / metabolism. Phosphorylation / drug effects. Rats. Signal Transduction / drug effects. Up-Regulation

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  • (PMID = 18076070.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Protein Kinase Inhibitors; 0 / Quinazolines; EC 2.7.10.1 / Erbb2 protein, mouse; EC 2.7.10.1 / Receptor, ErbB-2; EC 2.7.12.2 / Mitogen-Activated Protein Kinase Kinases; S65743JHBS / gefitinib
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8. Carrillo JF, Vázquez R, Ramírez-Ortega MC, Cano A, Ochoa-Carrillo FJ, Oñate-Ocaña LF: Multivariate prediction of the probability of recurrence in patients with carcinoma of the parotid gland. Cancer; 2007 May 15;109(10):2043-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multivariate prediction of the probability of recurrence in patients with carcinoma of the parotid gland.
  • BACKGROUND: Parotid gland carcinoma is an infrequent tumor, and series that report on these neoplasms are relatively scarce in the literature.
  • The objective of the current study was to identify prognostic factors in patients with parotid gland carcinoma and to develop a method for defining the probability of recurrence.
  • METHODS: Patients with parotid gland carcinoma who were treated at the authors' institution from January 1981 through December 2004 and who completed treatment constituted the study group.
  • Mucoepidermoid carcinoma was diagnosed in 34.6% of patients, adenoid cystic was diagnosed in 15.7% of patients, adenocarcinoma was diagnosed in 14.3% of patients, and acinic cell carcinoma was diagnosed in 9.4% of patients.
  • [MeSH-major] Carcinoma / therapy. Neoplasm Recurrence, Local. Parotid Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Logistic Models. Male. Middle Aged. Models, Statistical. Parotid Gland / surgery. Prognosis

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  • [Copyright] (c) 2007 American Cancer Society
  • (PMID = 17410532.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Michail P, Karavokyros I, Pikoulis E, Arvelakis A, Charminis G, Michail O, Theodoros D: Acinic cell carcinoma of the parotid gland in children: a case report and literature review. West Indian Med J; 2008 Jan;57(1):70-2
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  • [Title] Acinic cell carcinoma of the parotid gland in children: a case report and literature review.
  • Parotid acinic cell carcinoma is a rare malignancy in childhood.
  • The radiologic evaluation showed a parotid mass.
  • Tumour resection revealed acinic cell carcinoma of the parotid gland.
  • We review the literature on acinic cell carcinomas of parotid glands in childhood.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19565943.001).
  • [ISSN] 0043-3144
  • [Journal-full-title] The West Indian medical journal
  • [ISO-abbreviation] West Indian Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Jamaica
  • [Number-of-references] 26
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10. Goldman NC, Lee J, Tolley B: Acinic cell carcinoma of the parotid gland. Otolaryngol Head Neck Surg; 2007 Nov;137(5):828-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acinic cell carcinoma of the parotid gland.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Parotid Neoplasms / pathology

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  • (PMID = 17967654.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Kim SA, Mathog RH: Acinic cell carcinoma of the parotid gland: a 15-year review limited to a single surgeon at a single institution. Ear Nose Throat J; 2005 Sep;84(9):597-602
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acinic cell carcinoma of the parotid gland: a 15-year review limited to a single surgeon at a single institution.
  • The course of acinic cell carcinoma of the parotid gland following surgical and nonsurgical interventions is variable.
  • During that time, we found no recurrences of acinic cell carcinoma and no evidence of metastatic disease.
  • Therefore, we conclude that acinic cell carcinoma can be successfully treated with a superficial or total parotidectomy with sparing of the facial nerve.
  • [MeSH-major] Carcinoma, Acinar Cell / diagnosis. Carcinoma, Acinar Cell / therapy. Parotid Gland / surgery. Parotid Neoplasms / diagnosis. Parotid Neoplasms / therapy

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  • (PMID = 16261761.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Varsegi MF, Ravis SM, Hattab EM, Henley JD, Billings SD: Widespread cutaneous metastases from acinic cell carcinoma 20 years after primary presentation. J Cutan Pathol; 2008 Jun;35(6):591-3
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  • [Title] Widespread cutaneous metastases from acinic cell carcinoma 20 years after primary presentation.
  • Acinic cell carcinoma is a rare, low-grade malignant salivary gland neoplasm.
  • We present a case of widespread cutaneous metastasis from acinic cell carcinoma arising in a 59-year-old woman with a history of acinic cell carcinoma of the parotid gland 20 years prior to her cutaneous disease.
  • To our knowledge, is the first report of widespread cutaneous metastasis from acinic cell carcinoma.
  • [MeSH-major] Carcinoma, Acinar Cell / secondary. Parotid Neoplasms / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biopsy. Cell Nucleus / pathology. Cytoplasmic Granules / pathology. Female. Humans. Middle Aged. Periodic Acid-Schiff Reaction

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  • (PMID = 18261112.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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13. Sato T, Kamata SE, Kawabata K, Nigauri T, Mitani H, Beppu T, Sato M: Acinic cell carcinoma of the parotid gland in a child. Pediatr Surg Int; 2005 May;21(5):377-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acinic cell carcinoma of the parotid gland in a child.
  • Acinic cell carcinoma of the parotid gland in children is an extremely rare occurrence.
  • We present a 13-year-old girl with acinic cell carcinoma of the parotid gland.
  • Removal of the superficial lobe of the parotid gland (superficial parotidectomy) was performed because the tumor was completely encapsulated by fibrous tissue and had not invaded the deep parotid gland.
  • [MeSH-major] Carcinoma, Acinar Cell / surgery. Parotid Neoplasms / surgery

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  • [Cites] Int J Pediatr Otorhinolaryngol. 1987 Oct;13(3):279-92 [3679684.001]
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  • (PMID = 15806422.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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14. González-Peramato P, Jiménez-Heffernan JA, López-Ferrer P, Vicandi B, Viguer JM: Fine needle aspiration cytology of dedifferentiated acinic cell carcinoma of the parotid gland: a case report. Acta Cytol; 2006 Jan-Feb;50(1):105-8
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  • [Title] Fine needle aspiration cytology of dedifferentiated acinic cell carcinoma of the parotid gland: a case report.
  • BACKGROUND: Dedifferentiation of acinic cell carcinoma (ACC) to undifferentiated carcinoma occurs rarely and entails a poor prognosis.
  • CASE: An 85-year-old man presented with 2 nodular areas in the right parotid area.
  • They were distributed in small and larger, branching groups with acinic morphology.
  • A cytologic diagnosis of "salivary carcinoma with coexisting areas of acinic cell differentiation and high grade, undifferentiated carcinoma" was given.
  • Histopathology revealed a well-differentiated ACC with areas of high grade undifferentiated carcinoma (dedifferentiated ACC).
  • [MeSH-major] Carcinoma / diagnosis. Carcinoma, Acinar Cell / diagnosis. Epithelial Cells / pathology. Parotid Gland / pathology. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Biopsy, Fine-Needle. Cell Differentiation. Humans. Male

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  • (PMID = 16514851.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Spencer ML, Neto AG, Fuller GN, Luna MA: Intracranial extension of acinic cell carcinoma of the parotid gland. Arch Pathol Lab Med; 2005 Jun;129(6):780-2
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  • [Title] Intracranial extension of acinic cell carcinoma of the parotid gland.
  • We report the case of a 47-year-old woman who experienced multiple recurrences of acinic cell carcinoma, lung metastasis, and intracranial extension of the tumor during a 32-year period.
  • In this report, the clinical, microscopic, histochemical, and electron microscopy features of this acinic cell carcinoma are described, and a review of published information about this neoplasm is presented.
  • [MeSH-major] Brain Neoplasms / secondary. Carcinoma, Acinar Cell / secondary. Neoplasm Recurrence, Local / pathology. Parotid Neoplasms / pathology

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  • (PMID = 15913428.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Cohn ML, Elliott DD, El-Naggar AK: Metastatic acinic cell carcinoma in a neurofibroma mistaken for carcinosarcoma. Head Neck; 2005 Jan;27(1):76-80
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  • [Title] Metastatic acinic cell carcinoma in a neurofibroma mistaken for carcinosarcoma.
  • BACKGROUND: Tumor-to-tumor metastasis is a rare, but well-recognized, entity most commonly involving metastatic carcinoma to a mesenchymal neoplasm.
  • We report a case of acinic cell carcinoma of the parotid gland metastatic to a neurofibroma.
  • METHODS AND RESULTS: A 55-year-old man with a history of a high-grade acinic cell carcinoma of the parotid was seen with a mass at the surgical site and metastatic foci in the scalp 10 months postoperatively.
  • The resection specimen revealed a spindle cell lesion with metastatic foci of high-grade adenocarcinoma, initially diagnosed as a carcinosarcoma.
  • The bland morphology and S-100-positive expression of the spindle cell lesion confirmed the diagnosis of neurofibroma.
  • CONCLUSION: To our knowledge, this is the first reported case of acinic cell carcinoma metastatic to a neurofibroma, an important entity in the differential diagnosis of biphasic tumors of the head and neck.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Carcinosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Neurofibroma / pathology. Parotid Neoplasms / pathology. Salivary Gland Neoplasms / pathology

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  • [Copyright] Copyright 2004 Wiley Periodicals, Inc.
  • (PMID = 15565563.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Delides A, Velegrakis G, Kontogeorgos G, Karagianni E, Nakas D, Helidonis E: Familial bilateral acinic cell carcinoma of the parotid synchronous with pituitary adenoma: case report. Head Neck; 2005 Sep;27(9):825-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Familial bilateral acinic cell carcinoma of the parotid synchronous with pituitary adenoma: case report.
  • BACKGROUND: Acinic cell carcinoma is a common neoplasm of the salivary glands that occurs predominately in the parotid.
  • METHODS: History files and histologic reports of a patient with bilateral multifocal acinic cell carcinoma of the parotid and a synchronous pituitary adenoma, and of the patient's sister and his father, also treated for parotid tumours, were retrieved.
  • RESULTS: There was one recurrence of acinic cell carcinoma in the family.
  • CONCLUSIONS: This is the 17th case of bilateral acinic cell carcinoma of the parotid gland and the second reported case with a familial recurrence.
  • [MeSH-major] Adenoma / diagnosis. Carcinoma, Acinar Cell / diagnosis. Neoplasms, Multiple Primary / diagnosis. Parotid Neoplasms / diagnosis. Pituitary Neoplasms / diagnosis

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  • [Copyright] (c) 2005 Wiley Periodicals, Inc.
  • (PMID = 15920750.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Lin WN, Huang HC, Wu CC, Liao CT, Chen IH, Kan CJ, Huang SF: Analysis of acinic cell carcinoma of the parotid gland - 15 years experience. Acta Otolaryngol; 2010 Dec;130(12):1406-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Analysis of acinic cell carcinoma of the parotid gland - 15 years experience.
  • CONCLUSION: In our experience, the prognosis for parotid gland acinic cell carcinoma (AciCC) is good.
  • OBJECTIVES: AciCC is a rare tumor in parotid gland malignancy.
  • [MeSH-major] Carcinoma, Acinar Cell / surgery. Parotid Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Disease-Free Survival. Dose Fractionation. Female. Follow-Up Studies. Humans. Lymphatic Irradiation. Male. Middle Aged. Neoplasm Staging. Parotid Gland / pathology. Parotid Gland / surgery. Prognosis. Radiotherapy, Adjuvant. Retrospective Studies. Young Adult

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  • (PMID = 20809887.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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19. Jamieson L, Taylor SM, Smith A, Bullock MJ, Davis M: Metastatic acinic cell carcinoma of the parotid gland with ectopic ACTH syndrome. Otolaryngol Head Neck Surg; 2007 Jan;136(1):149-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic acinic cell carcinoma of the parotid gland with ectopic ACTH syndrome.
  • [MeSH-major] ACTH Syndrome, Ectopic / complications. Carcinoma, Acinar Cell / complications. Carcinoma, Acinar Cell / secondary. Parotid Neoplasms / complications. Parotid Neoplasms / pathology
  • [MeSH-minor] Fatal Outcome. Female. Humans. Liver Neoplasms / secondary. Middle Aged. Parotid Gland / surgery

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  • (PMID = 17210357.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Tavora F, Rassaei N, Shilo K, Foss RD, Galvin JR, Travis WD, Franks TJ: Occult primary parotid gland acinic cell adenocarcinoma presenting with extensive lung metastasis. Arch Pathol Lab Med; 2007 Jun;131(6):970-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Occult primary parotid gland acinic cell adenocarcinoma presenting with extensive lung metastasis.
  • Acinic cell adenocarcinoma is a malignant salivary gland neoplasm with a relatively low rate of lymphangitic spread to regional lymph nodes.
  • We encountered an unusual example of acinic cell adenocarcinoma that initially presented in the lung, whereas the primary parotid carcinoma, despite extensive clinical evaluation, only became apparent 1 year after initial diagnosis.
  • The histologic, immunohistochemical, and ultrastructural features of the tumor in the parotid gland and lung were similar.
  • This presentation is unique, showing that peripheral lung tumors of salivary gland type are likely to be metastatic, and careful clinical evaluation is warranted in establishing their primary site of origin.
  • [MeSH-major] Carcinoma, Acinar Cell / secondary. Lung Neoplasms / secondary. Parotid Neoplasms / pathology

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  • (PMID = 17550329.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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21. Drut R, Giménez PO: Acinic cell carcinoma of salivary gland with massive deposits of globular amyloid. Int J Surg Pathol; 2008 Apr;16(2):202-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acinic cell carcinoma of salivary gland with massive deposits of globular amyloid.
  • We present the case of a 23-year-old woman with a parotid gland tumor, the fine-needle aspiration biopsy smears of which showed epithelial cells with wide cytoplasm, isolated or arranged in micropapillary groups together with psammoma bodies.
  • The surgical specimen contained a 5-cm tumor with the histologic features of an acinic cell carcinoma (ACC) with papillary areas.
  • Huge globular amyloid deposits, the suggested name for this material irrespective of the type of amyloid, have not been previously reported in ACC of salivary gland.
  • [MeSH-major] Amyloid / metabolism. Carcinoma, Acinar Cell / pathology. Parotid Neoplasms / pathology

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  • (PMID = 18417682.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amyloid; 0 / Biomarkers, Tumor; 0 / Coloring Agents; 3U05FHG59S / Congo Red
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22. Yildirim N, Oksüzoğlu B, Vural M, Han O, Zengin N: Case report: cavernous sinus metastasis of the parotid carcinoma: a very unusual case. J Neurooncol; 2005 Jun;73(2):181-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case report: cavernous sinus metastasis of the parotid carcinoma: a very unusual case.
  • Cavernous sinus is an uncommon site of metastasis for the head and neck tumors, and especially for the tumors of parotid gland.
  • The case reported here is the second reported case of parotid carcinoma metastatic to the cavernous sinus, proven by histopathology.
  • Also it is the first reported parotid gland acinic cell carcinoma metastasis to the cavernous sinus.
  • [MeSH-major] Brain Neoplasms / secondary. Carcinoma, Acinar Cell / secondary. Cavernous Sinus / pathology. Parotid Neoplasms / pathology

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  • [Cites] Head Neck. 1990 Sep-Oct;12(5):426-9 [2211104.001]
  • [Cites] Otolaryngol Head Neck Surg. 2001 Nov;125(5):567-8 [11700465.001]
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  • (PMID = 15981110.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Chidzonga MM, Makunike-Mutasa R: Acinic cell carcinoma of the submandibular salivary gland presenting as a large cyst. Int J Oral Maxillofac Surg; 2007 Dec;36(12):1215-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acinic cell carcinoma of the submandibular salivary gland presenting as a large cyst.
  • Acinic cell carcinomas are rare tumours of salivary gland origin, most commonly seen in middle-aged women and predominantly in the parotid gland.
  • The case of a long-standing, predominantly cystic, acinic cell carcinoma located in the submandibular gland of a child is presented here.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Submandibular Gland Neoplasms / pathology

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  • (PMID = 17629459.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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24. Suh SI, Seol HY, Kim TK, Lee NJ, Kim JH, Kim KA, Woo JS, Lee JH: Acinic cell carcinoma of the head and neck: radiologic-pathologic correlation. J Comput Assist Tomogr; 2005 Jan-Feb;29(1):121-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acinic cell carcinoma of the head and neck: radiologic-pathologic correlation.
  • OBJECTIVE: To describe and correlate the imaging and pathologic findings of acinic cell carcinoma (ACC) in the head and neck.
  • RESULTS: The lesions in the superficial lobe of the parotid gland were solid (n=7), cystic (n=1), and cystic mass with mural nodule (n=1) on CT.
  • All solid masses in the parotid gland (n=7) included focal low-attenuating portions on CT, which were microcyst, hemorrhage, or necrosis on pathologic examination.
  • Internal hemorrhage on the MR images was seen in a parapharyngeal and a parotid lesion.
  • [MeSH-major] Carcinoma, Acinar Cell / radiography. Head and Neck Neoplasms / radiography
  • [MeSH-minor] Adult. Aged. Child, Preschool. Diagnosis, Differential. Female. Hemorrhage / pathology. Hemorrhage / radiography. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Necrosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / radiography. Palatal Neoplasms / pathology. Palatal Neoplasms / radiography. Parotid Neoplasms / pathology. Parotid Neoplasms / radiography. Pharyngeal Neoplasms / pathology. Pharyngeal Neoplasms / radiography. Retrospective Studies. Submandibular Gland Neoplasms / pathology. Submandibular Gland Neoplasms / radiography. Tomography, X-Ray Computed

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  • (PMID = 15665697.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Negahban S, Daneshbod Y, Khademi B, Seif I: Papillary cystic acinic cell carcinoma with many psammoma bodies, so-called psammoma body-rich papillary cystic acinic cell carcinoma: report of a case with fine needle aspiration findings. Acta Cytol; 2009 Jul-Aug;53(4):440-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papillary cystic acinic cell carcinoma with many psammoma bodies, so-called psammoma body-rich papillary cystic acinic cell carcinoma: report of a case with fine needle aspiration findings.
  • Psammoma bodies are infrequent in salivary gland aspirates.
  • We present a case of papillary cystic acinic cell carcinoma with many psammoma bodies and discuss the diagnostic pitfalls with other salivary gland tumors.
  • Physical examination demonstrated a 2 x 2-cm, nontender, rubbery mass inferior to the auricle in the left parotid area.
  • Sonography showed a 2-cm, cystic mass in the left parotid.
  • A preliminary diagnosis of papillary cystic salivary gland neoplasm was made and supeficial parotidectomy performed.
  • A diagnosis of papillary cystic acinic cell carcinoma with many psammoma bodies was made.
  • Aspiration cytology of papillary cystic acinic cell carcinoma with many psammoma bodies can be confused with more common tumors, such as cystic mixed tumor and adenoid cystic carcinoma with cannonballs, low grade mucoepidermoid carcinoma or cystic papillary carcinoma of the thyroid.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Carcinoma, Papillary / pathology. Diagnosis, Differential. Female. Humans

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  • (PMID = 19697733.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Neto AG, Pineda-Daboin K, Spencer ML, Luna MA: Sinonasal acinic cell carcinoma: a clinicopathologic study of four cases. Head Neck; 2005 Jul;27(7):603-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sinonasal acinic cell carcinoma: a clinicopathologic study of four cases.
  • BACKGROUND: Acinic cell carcinoma is a low-grade malignant epithelial salivary gland neoplasm with a predilection for the parotid gland.
  • To date, only 11 cases of sinonasal acinic cell carcinomas have been reported in the English-language literature.
  • We present the clinicopathologic features of four sinonasal acinic cell carcinomas.
  • METHODS: The demographic data and pathologic material of four patients with sinonasal acinic cell carcinoma identified from the files of the Department of Pathology at The University of Texas M. D.
  • CONCLUSIONS: Sinonasal acinic cell carcinoma is a distinct low-grade carcinoma that can be distinguished from other neoplasms by light microscopy and histochemical staining methods.
  • Pathologists and surgeons should be aware of the occurrence of this type of salivary gland neoplasm in the sinonasal tract.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Nose Neoplasms / pathology

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  • (PMID = 15900565.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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27. da Silva AA, Graner E, Jorge J, Vargas PA, Lopes MA: Intraoral acinic cell carcinoma: case report and review of the literature. Gen Dent; 2008 Nov-Dec;56(7):e43-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoral acinic cell carcinoma: case report and review of the literature.
  • Acinic cell carcinoma (ACC) is an uncommon salivary gland tumor that primarily affects the parotid gland.
  • [MeSH-major] Carcinoma, Acinar Cell / diagnosis. Mouth Neoplasms / diagnosis

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  • (PMID = 21444272.001).
  • [ISSN] 0363-6771
  • [Journal-full-title] General dentistry
  • [ISO-abbreviation] Gen Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Tanahashi C, Yabuki S, Akamine N, Yatabe Y, Ichihara S: Pure acinic cell carcinoma of the breast in an 80-year-old Japanese woman. Pathol Int; 2007 Jan;57(1):43-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pure acinic cell carcinoma of the breast in an 80-year-old Japanese woman.
  • Acinic cell carcinoma of the breast is an uncommon neoplasm.
  • Since the first case of this rare variant of breast carcinoma was reported in 1996, only 10 cases have been reported in the English-language literature.
  • Reported herein is the first case of primary acinic cell carcinoma of the breast in a Japanese woman.
  • Microscopically, the tumor was predominantly made up of a monotonous proliferation of cells with a finely granular cytoplasm, resembling acinic cells of the parotid gland.
  • In spite of extensive sampling, no common histological patterns of breast carcinoma such as in situ and invasive ductal carcinoma were recognized in the present case, indicating that the present case was pure acinic cell carcinoma.
  • In addition, the immunohistochemical profile of this tumor was identical to that of the acinic cell carcinoma of the salivary gland: estrogen receptor, progesterone receptor, HER2 and cytokeratin (CK)20 were negative and amylase and CK7 were positive.
  • [MeSH-major] Breast Neoplasms / diagnosis. Breast Neoplasms / pathology. Carcinoma, Acinar Cell / diagnosis. Carcinoma, Acinar Cell / pathology


29. Cho JH, Yoon SY, Bae EY, Lee CN, Lee JD, Cho SH: Acinic cell carcinoma on the lower lip resembling a mucocele. Clin Exp Dermatol; 2005 Sep;30(5):490-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acinic cell carcinoma on the lower lip resembling a mucocele.
  • Positive staining was observed with Periodic acid-Shiff, and immunohistochemistry for cytokeratin, alpha-1 antitrypsin, and S-100 protein resulting in a final diagnosis of acinic cell carcinoma.
  • Acinic cell carcinoma represents a well-established, although uncommon, entity in the classification of neoplasms of salivary gland origin.
  • The parotid salivary gland is the most frequent site of acinic cell carcinoma, whereas the lip is a particularly unusual site.
  • Given these findings, we suggest that acinic cell carcinoma should be considered in the differential diagnosis of any mucocele-like mass on the lower lip.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Lip Neoplasms / pathology. Mucocele / pathology

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  • (PMID = 16045674.001).
  • [ISSN] 0307-6938
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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30. Johnykutty S, Miller CH, Hoda RS, Giampoli EJ: Fine-needle aspiration of dedifferentiated acinic cell carcinoma: Report of a case with cyto-histological correlation. Diagn Cytopathol; 2009 Oct;37(10):763-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration of dedifferentiated acinic cell carcinoma: Report of a case with cyto-histological correlation.
  • Dedifferentiated Acinic Cell Carcinoma (DAcCC) is a rare salivary gland malignancy.
  • [MeSH-major] Parotid Neoplasms / pathology
  • [MeSH-minor] Aged. Biopsy, Fine-Needle. Carcinoma, Acinar Cell / pathology. Carcinoma, Acinar Cell / surgery. Cell Differentiation. Female. Humans. Lymphatic Metastasis / pathology

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19526576.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Mazouzi A, Benjelloun H, Benchekroun N, Acharki A, Benider A: [Clear cell carcinoma of the parotid gland]. Ann Otolaryngol Chir Cervicofac; 2005 Jun;122(3):142-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clear cell carcinoma of the parotid gland].
  • OBJECTIVES: Clear cell carcinomas of the parotid gland are hardly reported only fifty cases are known.
  • They are characterized by a proliferation of acinic epithelial cells and of clear myo epithelial cells.
  • The diagnosis was established by the parotid biopsy in 2 cases and after surgery in the third case.
  • CONCLUSION: With an in-depth analysis we can notice that clear cell carcinomas of the parotid gland are rare and mostly occur to old patients.
  • [MeSH-major] Adenocarcinoma, Clear Cell / surgery. Parotid Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Biopsy. Female. Humans. Immunohistochemistry. Male. Middle Aged. Parotid Gland / pathology. Parotid Gland / surgery. Prognosis

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  • (PMID = 16142093.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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32. Roy S, Dhingra KK, Gupta P, Khurana N, Gupta B, Meher R: Acinic cell carcinoma with extensive neuroendocrine differentiation: a diagnostic challenge. Head Neck Pathol; 2009 Jun;3(2):163-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acinic cell carcinoma with extensive neuroendocrine differentiation: a diagnostic challenge.
  • Primary salivary gland carcinoma with neuroendocrine differentiation is of rare occurrence, especially so in the parotid gland.
  • Amongst the various reported primary tumors with neuroendocrine differentiation, acinic cell carcinoma (ACC) one such tumor.
  • Initial histopathological examination of the tumor was suggestive of neuroendocrine carcinoma.
  • The possibility of neuroendocrine differentiation in a primary salivary gland tumor should be kept in mind whenever a salivary gland tumor shows only neuroendocrine histology.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Parotid Neoplasms / pathology

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  • [Cites] Pathobiology. 1990;58(4):212-20 [1701303.001]
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  • (PMID = 19644544.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Acinic cell / Carcinoma / Chromogranin / Neuroendocrine / Parotid / Warthin’s
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33. Prieto-Rodríguez M, Artés-Martínez MJ, Navarro-Hervás M, Camañas-Sanz A, Vera-Sempere FJ: Cytological characteristics of acinic cell carcinoma (ACC) diagnosed by fine-needle aspiration biopsy (FNAB). A study of four cases. Med Oral Patol Oral Cir Bucal; 2005 Mar-Apr;10(2):103-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytological characteristics of acinic cell carcinoma (ACC) diagnosed by fine-needle aspiration biopsy (FNAB). A study of four cases.
  • OBJECTIVE: To present the cytopathological characteristics of acinic cell carcinoma (ACC) as well as its cyto-histological correlation, commenting on the differential diagnostic problems of this entity based on four observations studied using fine-needle aspiration biopsy (FNAB).
  • CLINICAL CASES: Two males of 52 and 53 years of age, one 79 year-old woman and a girl of 12 years of age, who presented tumors located in the parotid area (cases 1, 2 and 4) and at the laterocervical level (case 3).
  • In 3 patients, the FNAB was, together with the image studies, the first diagnostic indication; case 3 corresponding to a puncture of metastatic laterocervical adenopathies in a patient with a history of parotid ACC.
  • DISCUSSION: FNAB provides essential information on the diagnostic-therapeutic management of salivary gland tumors; this methodology is highly sensitive in its diagnostic efficacy.
  • The diagnosis of ACCs frequently presents difficulties, owing to the great cytologic similarity of the tumor cells with the normal acinar component of the salivary gland.
  • The differential diagnosis is considered, fundamentally, with clear cell carcinomas, mucoepidermoid carcinomas, Warthin s tumor, and oncocytomas.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology

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  • (PMID = 15735541.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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34. Chan WH, Lee KW, Chiang FY, Ho KY, Chai CY, Kuo WR: Features of parotid gland diseases and surgical results in southern Taiwan. Kaohsiung J Med Sci; 2010 Sep;26(9):483-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Features of parotid gland diseases and surgical results in southern Taiwan.
  • Various parotid gland diseases are seen clinically, including inflammation, sialolithiasis, and benign and malignant tumors.
  • Here, we investigated the relationship between tumor characteristics and pathology, and considered whether the former could be used to differentiate malignant from benign parotid gland diseases.
  • In malignant disease, the most common was acinic cell carcinoma (8 cases, 22.9%).
  • Compared with benign disease, malignant parotid gland disease more often presents as a hard, painful, fixed and large mass (> 3 cm), and more often involves the deep lobe of the parotid gland.
  • However, there was no difference in transient facial palsy rate between benign and malignant parotid gland disease, although parotid gland cancer had a higher incidence of permanent facial palsy postoperatively.
  • [MeSH-major] Parotid Diseases / pathology. Parotid Diseases / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Male. Middle Aged. Parotid Gland / pathology. Parotid Gland / surgery. Postoperative Complications / epidemiology. Retrospective Studies. Taiwan / epidemiology. Treatment Outcome. Young Adult

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  • [Copyright] Copyright © 2010 Elsevier. Published by Elsevier B.V. All rights reserved.
  • [CommentIn] Kaohsiung J Med Sci. 2012 Jun;28(6):350-1 [22632893.001]
  • (PMID = 20837345.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China (Republic : 1949- )
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35. van Tongeren J, Creytens DH, Meulemans EV, de Bondt RB, de Jong J, Manni JJ: Synchronous bilateral epithelial-myoepithelial carcinoma of the parotid gland: case report and review of the literature. Eur Arch Otorhinolaryngol; 2009 Sep;266(9):1495-500
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous bilateral epithelial-myoepithelial carcinoma of the parotid gland: case report and review of the literature.
  • Synchronous bilateral malignancy in the parotid glands is extremely rare.
  • The most common synchronous bilateral malignancies are acinic cell carcinoma.
  • Epithelial-myoepithelial carcinoma is an uncommon neoplasm comprising 1% of all salivary gland tumours.
  • In this case report, we describe, to our best of knowledge, the first case of a patient with a synchronous bilateral epithelial-myoepithelial carcinoma of the parotid gland.
  • Imaging studies like ultrasonography are mandatory for both parotid glands and upper necks in the clinical presence of a unilateral parotid gland tumour.
  • [MeSH-major] Carcinoma / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 18841376.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 35
  • [Other-IDs] NLM/ PMC2718197
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36. Lima RA, Tavares MR, Dias FL, Kligerman J, Nascimento MF, Barbosa MM, Cernea CR, Soares JR, Santos IC, Salviano S: Clinical prognostic factors in malignant parotid gland tumors. Otolaryngol Head Neck Surg; 2005 Nov;133(5):702-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical prognostic factors in malignant parotid gland tumors.
  • OBJECTIVE: To analyze the factors in parotid malignant epithelial tumors influencing recurrences and disease-specific survival.
  • RESULTS: Forty patients had mucoepidermoid carcinoma, 18 patients adenocarcinoma NOS, 18 patients acinic cell carcinoma, 15 patients adenoid cystic carcinoma, 11 patients malignant mixed tumor, 11 patients salivary duct carcinoma, and 13 patients other pathology.
  • [MeSH-major] Adenocarcinoma / mortality. Adenocarcinoma / therapy. Neoplasm Invasiveness / pathology. Parotid Neoplasms / mortality. Parotid Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Child. Child, Preschool. Cohort Studies. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Multivariate Analysis. Neck Dissection / methods. Neoplasm Staging. Parotid Gland / radiation effects. Parotid Gland / surgery. Probability. Proportional Hazards Models. Radiotherapy, Adjuvant. Retrospective Studies. Risk Assessment. Sex Factors. Survival Analysis. Time Factors. Treatment Outcome

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  • (PMID = 16274796.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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37. Cheuk DK, Shek TW, Chan GC, Lau YL, Ha SY, Chiang AK: Parotid acinar cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer; 2008 Mar;50(3):636-9
Hazardous Substances Data Bank. METHOTREXATE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parotid acinar cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia.
  • Salivary gland tumors account for about 6% of the second cancers.
  • The majority of these are mucoepidermoid carcinomas (MEC) of the parotid gland.
  • We report the clinical and pathological features of a rarer histological type, acinic cell carcinoma (ACC), in a childhood acute lymphoblastic leukemia (ALL) survivor.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Carcinoma, Acinar Cell / etiology. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / etiology. Parotid Neoplasms / etiology. Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Whole-Body Irradiation / adverse effects
  • [MeSH-minor] 6-Mercaptopurine / administration & dosage. 6-Mercaptopurine / adverse effects. Adenoma, Sweat Gland / etiology. Adenoma, Sweat Gland / surgery. Asparaginase / administration & dosage. Asparaginase / adverse effects. Child, Preschool. Combined Modality Therapy / adverse effects. Cyclophosphamide / administration & dosage. Cyclophosphamide / adverse effects. Cytarabine / administration & dosage. Cytarabine / adverse effects. Daunorubicin / administration & dosage. Daunorubicin / adverse effects. Epirubicin / administration & dosage. Epirubicin / adverse effects. Etoposide / administration & dosage. Etoposide / adverse effects. Follow-Up Studies. Humans. Male. Methotrexate / administration & dosage. Methotrexate / adverse effects. Prednisolone / administration & dosage. Prednisolone / adverse effects. Recurrence. Remission Induction. Survivors. Sweat Gland Neoplasms / etiology. Sweat Gland Neoplasms / surgery. Vincristine / administration & dosage. Vincristine / adverse effects

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 16865683.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 04079A1RDZ / Cytarabine; 3Z8479ZZ5X / Epirubicin; 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; E7WED276I5 / 6-Mercaptopurine; EC 3.5.1.1 / Asparaginase; YL5FZ2Y5U1 / Methotrexate; ZS7284E0ZP / Daunorubicin; UKALL X protocol
  • [Number-of-references] 17
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38. Kawahara A, Harada H, Mihashi H, Akiba J, Kage M: Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review. Diagn Cytopathol; 2010 May;38(5):377-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review.
  • Cystadenocarcinoma is a rare malignant tumor, with an estimated incidence of 2% of malignant salivary gland tumors.
  • A 23-year-old man presented with an asymptomatic mass in the left parotid gland that had been present for 2 years.
  • Preoperative fine-needle aspiration cytology (FNAC) showed a small number of tumor cell clusters in the cystic fluid.
  • The papillary-cystic variant of acinic cell carcinoma (ACC-PCV) was suggested from these findings on FNAC.
  • As tumor cells with a small vacuolated, soap-bubble appearance of the cytoplasm are common findings of both cystadenocarcinoma and ACC-PCV, they are of little use for differentiation; however, they are so characteristic that the majority of benign salivary gland lesions with cystic structures can be excluded, if enough attention is paid.
  • [MeSH-major] Cyst Fluid / cytology. Cystadenocarcinoma / diagnosis. Cystadenocarcinoma / pathology. Diagnostic Errors. Parotid Gland / pathology. Parotid Neoplasms / diagnosis. Parotid Neoplasms / pathology

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  • (PMID = 19927358.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 110
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39. Vageli D, Sourvinos G, Ioannou M, Koukoulis GK, Spandidos DA: High-risk human papillomavirus (HPV) in parotid lesions. Int J Biol Markers; 2007 Oct-Dec;22(4):239-44
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High-risk human papillomavirus (HPV) in parotid lesions.
  • Although several studies have reported that oropharyngeal infection with HPV may predispose to tumorigenesis, little is known about the etiological factors of salivary gland tumors and the presence of HPV.
  • We studied 9 parotid lesions for HPV infection including an oncocytoma, an acinic cell carcinoma, a high-grade adenocarcinoma, a low-grade polymorphous adenocarcinoma, a Warthin's tumor and 2 pleomorphic adenomas, a lymphoepithelial cyst and a lipoma of the parotid gland.
  • Seven of the 9 parotid lesions were HPV positive while 6 of these 7 had been infected by HPV16 and/or HPV18 oncogenic types.
  • Finally, in situ PCR indicated that HPV16 amplification occurred in the salivary gland tumors.
  • This is the first time that highrisk HPV genotypes are detected in these histological types of parotid lesions, suggesting the possible involvement of the virus in the disease.
  • [MeSH-major] Papillomaviridae / metabolism. Papillomavirus Infections / virology. Parotid Gland / pathology. Parotid Neoplasms / virology. Salivary Gland Neoplasms / virology

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  • [CommentIn] Int J Biol Markers. 2011 Oct-Dec;26(4):278-80 [22180174.001]
  • (PMID = 18161653.001).
  • [ISSN] 0393-6155
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / DNA Probes, HPV
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40. Chahwala Q, Siddaraju N, Singh N, Goneppanavar M, Basu D: Fine needle aspiration cytology of oncocytic lipoadenoma of the parotid gland: report of a rare case. Acta Cytol; 2009 Jul-Aug;53(4):437-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration cytology of oncocytic lipoadenoma of the parotid gland: report of a rare case.
  • BACKGROUND: Oncocytic lipoadenoma is an uncommon benign salivary gland tumor.
  • CASE: A 50-year-old woman presented with a slow-growing swelling in the left parotid region that was clinically interpreted as a soft tissue tumor, with a differential of neurofibroma/lipoma.
  • A remote possibility of acinic cell carcinoma with oncocytic features was also suggested.
  • CONCLUSION: Both cytopathologists and histopathologists need to be aware of oncocytic lipoadenoma of the salivary gland in order to diagnose it precisely.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19697732.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Habermann CR, Arndt C, Graessner J, Diestel L, Petersen KU, Reitmeier F, Ussmueller JO, Adam G, Jaehne M: Diffusion-weighted echo-planar MR imaging of primary parotid gland tumors: is a prediction of different histologic subtypes possible? AJNR Am J Neuroradiol; 2009 Mar;30(3):591-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diffusion-weighted echo-planar MR imaging of primary parotid gland tumors: is a prediction of different histologic subtypes possible?
  • BACKGROUND AND PURPOSE: Our aim was to determine the value of echo-planar diffusion-weighted MR imaging (epiDWI) in differentiating various types of primary parotid gland tumors.
  • MATERIALS AND METHODS: One hundred forty-nine consecutive patients with suspected tumors of the parotid gland were examined with an epiDWI sequence by using a 1.5T unit.
  • RESULTS: In 136 patients, a primary parotid gland tumor was confirmed by histology.
  • Mucoepidermoid carcinomas, acinic cell carcinomas, and basal cell adenocarcinomas were not differentiable from Warthin tumors (P = .094, .396, and .604, respectively).
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Echo-Planar Imaging. Myoepithelioma / pathology. Parotid Gland / pathology
  • [MeSH-minor] Adenolymphoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / pathology. Carcinoma, Mucoepidermoid / pathology. Diagnosis, Differential. Female. Humans. Lipoma / pathology. Male. Middle Aged. Prospective Studies. Salivary Gland Neoplasms / pathology. Young Adult

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  • (PMID = 19131405.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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42. Salgarelli AC, Capparè P, Bellini P, Collini M: Usefulness of fine-needle aspiration in parotid diagnostics. Oral Maxillofac Surg; 2009 Dec;13(4):185-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Usefulness of fine-needle aspiration in parotid diagnostics.
  • Among head and neck sites, the parotid gland is unique in the number, diversity, and peculiarity of its pathological processes.
  • This complexity has prompted a great deal of discussion regarding the application of FNA to parotid masses, primarily focusing on the reliability of FNA as a diagnostic tool in guiding patient management.
  • METHODS: This review presents an analysis of the usefulness of FNA in differential diagnosis of parotid pathologies.
  • RESULTS: Recent studies have confirmed a wide range of accuracy rates for FNA evaluation of parotid masses, varying from 79% to 97%.
  • FNA is notoriously unreliable in recognising the malignant nature of parotid carcinoma providing its precise classification and establishing its grade.
  • A few malignant neoplasms are particularly prone to diagnostic error: acinic cell carcinoma is frequently interpreted as benign, and low-grade lymphomas are often discounted as inflammatory processes.
  • For planning the extent of surgery of malignant parotid tumours, the histological subtype and/or grade should be determined; therefore, a histological diagnosis by frozen section analysis is required.
  • Regardless of whether FNA is used routinely or selectively in patients with parotid masses, the findings should contribute to, and not replace, the overall diagnostic impression.
  • [MeSH-major] Biopsy, Fine-Needle. Parotid Diseases / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19821124.001).
  • [ISSN] 1865-1569
  • [Journal-full-title] Oral and maxillofacial surgery
  • [ISO-abbreviation] Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 51
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43. Du LX, Yuan JP, Guan H, Zhang WD, Liang BL: [Magnetic resonance imaging for diagnosis of parotid malignant tumors and the pathological basis]. Nan Fang Yi Ke Da Xue Xue Bao; 2010 May;30(5):1107-10
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  • [Title] [Magnetic resonance imaging for diagnosis of parotid malignant tumors and the pathological basis].
  • OBJECTIVE: To investigate magnetic resonance imaging (MRI) features of parotid malignant tumors and study their pathological basis.
  • METHODS: Forty-seven patients with parotid malignant tumors confirmed by surgery (41 patients) or biopsy (6 patients) were enrolled in this study.
  • Each of the MRI features was analyzed retrospectively and the typical MRI findings of common parotid malignant tumors were summarized.
  • RESULTS: MRI allowed accurate diagnosis of parotid malignant tumors.
  • Four patients with low-grade mucoepidermoid carcinoma showed well-defined tumor margin and were difficult to distinguish from benign tumors.
  • Six patients with high-grade mucoepidermoid carcinoma had obscure margin of the tumor which easily underwent necrosis with liable lymph node involvement.
  • The 8 cases of adenoid cystic carcinoma was characterized by extensive invasion surrounding the parotid gland.
  • The 4 cases of acinic cell carcinoma showed either regular or irregular tumor morphology, presenting with high signal intensity on T1WI and T(2)WI.
  • CONCLUSION: MRI is an important modality for the diagnosis of parotid malignant tumors.
  • Most of the common parotid malignant tumors have characteristic MRI and pathological features, which make possible their differential diagnosis.
  • [MeSH-major] Magnetic Resonance Imaging. Parotid Neoplasms / diagnosis. Parotid Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / pathology. Female. Humans. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 20501408.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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44. Shen JX, Fan WJ, Lu YC, Xiao P: [Malignant epithelial parotid tumors: CT imaging and histopathologic correlation]. Ai Zheng; 2007 Jul;26(7):762-6
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  • [Title] [Malignant epithelial parotid tumors: CT imaging and histopathologic correlation].
  • BACKGROUND & OBJECTIVE: Malignant epithelial parotid tumors have various histopathologic types.
  • Computed tomography (CT) has been widely used to detect parotid masses.
  • This study was to analyze CT features of malignant epithelial parotid tumors to evaluate the diagnostic value of CT in the characterization of malignant epithelial parotid tumors.
  • METHODS: CT reports of 29 patients with malignant epithelial parotid tumors (8 at low grade and 21 at intermediate or high grade), confirmed by histopathology in Cancer Center of Sun Yat-sen University, were reviewed.
  • RESULTS: Of the 8 cases at low grade, 4 were well-differentiated mucoepidermoid carcinoma, 3 were acinic cell carcinoma, and 1 was epithelial-myoepithelial carcinoma; 3 had sharp margin, 3 had partly unsharp margin, and 2 had unsharp margin; 5 had regular contour, and 3 had irregular contour; all were enhanced obviously; 2 showed homogeneous appearance, and 6 showed inhomogeneous appearance with low-density areas; none had adjacent infiltration; 3 had lymph node metastasis.
  • Of the 21 cases at intermediate or high grade, 5 were poorly-differentiated squamous cell carcinoma, 8 were malignant pleomorphic adenoma, 2 were adenocarcinoma, 1 was lymph-epithelial carcinoma, 4 were mucoepidermoid carcinoma, and 1 was adenoidcystic carcinoma; 5 had sharp margin, 7 had partly unsharp margin, and 9 had unsharp margin; 10 had regular contour, and 11 had irregular contour; 17 were enhanced obviously, and the 4 cases of malignant pleomorphic adenoma were enhanced slightly; 9 showed homogeneous appearance, and 12 showed inhomogeneous appearance with low-density areas; 8 had adjacent infiltration (the fat space between tumor and the parotid bed disappeared); 6 had lymph node metastasis.
  • CONCLUSIONS: To some extent, CT features of malignant epithelial parotid tumors are correlated to the differentiation of tumor cells.
  • [MeSH-major] Carcinoma / pathology. Carcinoma / radiography. Parotid Neoplasms / pathology. Parotid Neoplasms / radiography. Tomography, X-Ray Computed
  • [MeSH-minor] Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / radiography. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Mucoepidermoid / pathology. Carcinoma, Mucoepidermoid / radiography. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / radiography. Female. Follow-Up Studies. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Neoplasm Staging. Parotid Gland / pathology. Parotid Gland / radiography. Young Adult

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  • (PMID = 17626755.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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45. Alphs HH, Eisele DW, Westra WH: The role of fine needle aspiration in the evaluation of parotid masses. Curr Opin Otolaryngol Head Neck Surg; 2006 Apr;14(2):62-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of fine needle aspiration in the evaluation of parotid masses.
  • Among head and neck sites, the parotid gland stands apart for the number, diversity and peculiarity of pathologic processes to target this structure.
  • This matchless complexity has prompted a thoughtful discussion regarding the application of the fine needle aspiration to parotid masses--a discussion that has primarily focused on the reliability of the fine needle aspiration as a diagnostic tool, and on its utility in guiding patient management.
  • RECENT FINDINGS: Recent studies have confirmed a high overall accuracy rate for fine needle aspiration evaluation of parotid masses, ranging from 90 to 95%.
  • Fine needle aspiration is notoriously unreliable in recognizing the malignant nature of the parotid carcinoma, providing its precise classification, and establishing its grade.
  • Acinic cell carcinoma is frequently interpreted as benign or even nonneoplastic; and low-grade lymphomas are often discounted as inflammatory processes.
  • SUMMARY: Parotid gland masses are not particularly conducive to diagnostic accuracy and precision by fine needle aspiration.
  • Whether one uses the fine needle aspiration routinely or selectively in patients with parotid masses, the fine needle aspiration findings should contribute to, not displace, the overall diagnostic impression.
  • [MeSH-major] Biopsy, Fine-Needle. Parotid Diseases / pathology
  • [MeSH-minor] Diagnosis, Differential. Frozen Sections. Humans. Parotid Neoplasms / pathology

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  • (PMID = 16552260.001).
  • [ISSN] 1068-9508
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 28
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46. Miliauskas JR, Hunt JL: Primary unilateral multifocal pleomorphic adenoma of the parotid gland: molecular assessment and literature review. Head Neck Pathol; 2008 Dec;2(4):339-42
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  • [Title] Primary unilateral multifocal pleomorphic adenoma of the parotid gland: molecular assessment and literature review.
  • Multiple separate tumors developing in a single salivary gland is rare in previously untreated patients.
  • Tumors that can be multicentric include Warthin tumor, oncocytoma, basal cell adenoma and acinic cell carcinoma.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Loss of Heterozygosity. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 20614306.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  • [Other-IDs] NLM/ PMC2807582
  • [Keywords] NOTNLM ; Multifocal / Parotid gland / Pleomorphic adenoma
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47. Whitt JC, Schafer DR, Callihan MD: Multiple malignant salivary gland neoplasms: mucoepidermoid carcinoma of palate and adenoid cystic carcinoma of floor of mouth. Head Neck Pathol; 2008 Mar;2(1):41-8
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  • [Title] Multiple malignant salivary gland neoplasms: mucoepidermoid carcinoma of palate and adenoid cystic carcinoma of floor of mouth.
  • Salivary gland tumors usually occur as single lesions.
  • We report a case of an adult male who presented with a mucoepidermoid carcinoma involving the minor salivary glands of the palate at age 57 years, followed by an adenoid cystic carcinoma of the floor of mouth at age 63 years.
  • There are 31 acceptable cases of multiple malignant salivary gland neoplasms reported in the world literature.
  • Bilateral acinic cell adenocarcinoma was the most frequent combination of multiple salivary gland malignancy, accounting for 14 cases (10 synchronous and four metachronous).
  • All involved the parotid glands bilaterally with the exception of one case that involved parotid and submandibular gland.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / pathology. Mouth Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Palatal Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

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  • (PMID = 20614341.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2807610
  • [Keywords] NOTNLM ; Metachronous neoplasms / Multiple malignant salivary gland neoplasms / Salivary gland neoplasms / Salivary gland tumors / Synchronous neoplasms
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48. Sakamoto K, Chijiwa H, Miyajima Y, Umeno H, Nakashima T: [A retrospective study of malignant parotid tumors]. Nihon Jibiinkoka Gakkai Kaiho; 2006 Feb;109(2):103-11

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A retrospective study of malignant parotid tumors].
  • The clinical features of 74 patients (39 men, 35 women; mean age, 62 years) with malignant parotid tumors were retrospectively investigated.
  • Tumors located in both lobes of the parotid gland were the most frequent type of tumor (49%).
  • Histopathologically, sixteen tumor types were observed; mucoepidermoid carcinoma was the most common.
  • As for the major histopathologic types, the five-year survival rates were 69% for mucoepidermoid carcinoma, 48% for adenocarcinoma, 71% for adenoid cystic carcinoma, and 100% for acinic cell carcinoma and malignant mixed tumor.
  • A total parotidectomy with total removal of the facial nerve seemed necessary for T3 and T4 cases, especially those with adenocarcinoma or mucoepidermoid carcinoma.
  • Modified neck dissection may be necessary for N0 cases, especially those with adenocarcinoma, adenoid cystic carcinoma or undifferentiated carcinoma.
  • [MeSH-major] Parotid Neoplasms

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  • (PMID = 16529017.001).
  • [ISSN] 0030-6622
  • [Journal-full-title] Nihon Jibiinkoka Gakkai kaiho
  • [ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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49. Zhang S, Bao R, Abreo F: Papillary oncocytic cystadenoma of the parotid glands: a report of 2 cases with varied cytologic features. Acta Cytol; 2009 Jul-Aug;53(4):445-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papillary oncocytic cystadenoma of the parotid glands: a report of 2 cases with varied cytologic features.
  • BACKGROUND: Papillary cystadenoma is a rare salivary gland neoplasm, and oncocytic change can be focal or marked.
  • Papillary oncocytic cystadenoma has been reported mainly in the minor salivary glands and occasionally in the parotid glands.
  • CASES: A 26-year-old female presented with a 2.4-cm, cystic right parotid gland mass present for 4 months.
  • A 52-year-old male presented with a 1.5-cm, cystic left parotid mass enlarging for the past few months.
  • CONCLUSION: Papillary cystadenoma is rare in the parotid glands, and cytologic features may vary.
  • Warthin's tumor, oncocytoma, intraductal papilloma and acinic cell carcinoma may arise in the differential diagnosis.
  • In cases with extensive necrotic debris and metaplastic squamous cells, branchial cyst and cystic metastatic squamous carcinoma may also need to be considered.
  • [MeSH-major] Cystadenoma, Papillary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19697734.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Nagliati M, Bolner A, Vanoni V, Tomio L, Lay G, Murtas R, Deidda MA, Madeddu A, Delmastro E, Verna R, Gabriele P, Amichetti M: Surgery and radiotherapy in the treatment of malignant parotid tumors: a retrospective multicenter study. Tumori; 2009 Jul-Aug;95(4):442-8

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  • [Title] Surgery and radiotherapy in the treatment of malignant parotid tumors: a retrospective multicenter study.
  • AIMS AND BACKGROUND: Major salivary gland cancers are rare, with many histologic types and subtypes.
  • The low incidence and heterogeneity of primary parotid carcinomas makes their outcome difficult to evaluate.
  • The present study reviews the experience of three Italian institutions in the treatment of primary parotid carcinomas in order to describe the clinicopathological presentation and treatment options with emphasis on radiotherapy and to analyze the factors influencing survival.
  • METHODS AND STUDY DESIGN: The records of 110 patients with primary parotid neoplastic lesions treated at three Italian institutions from 1993 to 2004 were retrospectively reviewed.
  • The most frequent histologies were adenoid cystic carcinoma (n = 16), mucoepidermoid carcinoma (n = 15), and acinic cell carcinoma (n = 15).
  • CONCLUSIONS: The treatment of salivary gland malignancies remains primarily surgical.
  • [MeSH-major] Parotid Neoplasms / radiotherapy. Parotid Neoplasms / surgery

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  • (PMID = 19856654.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Italy
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51. Luukkaa H, Klemi P, Leivo I, Koivunen P, Laranne J, Mäkitie A, Virtaniemi J, Hinkka S, Grénman R: Salivary gland cancer in Finland 1991--96: an evaluation of 237 cases. Acta Otolaryngol; 2005 Feb;125(2):207-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Salivary gland cancer in Finland 1991--96: an evaluation of 237 cases.
  • CONCLUSION: In this material consisting of various salivary gland carcinomas, stage I, male gender and age were the most powerful predictors of patient outcome.
  • OBJECTIVES: To retrieve the records of all salivary gland cancer (SGC) patients diagnosed in Finland between 1991 and 1996 and to evaluate the incidence, histological type and location of SGC, the treatment given and the outcome.
  • The commonest tumor location was the parotid gland (n = 152; 64%), followed by the minor salivary glands (n =46; 19%), the submandibular gland (n =38; 16%) and the sublingual gland (n = 1; 0.4%).
  • The most frequent histological types of SGC were adenoid cystic carcinoma (n =65; 27%), mucoepidermoid carcinoma (n =45; 19%) and acinic cell carcinoma (n =41; 17%).
  • Of the commonest tumor types, the best 5-year relative survival rate was for patients with acinic cell carcinoma (96%), followed by those with mucoepidermoid (79%) and adenoid cystic carcinoma (74%).
  • [MeSH-major] Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma / epidemiology. Carcinoma / mortality. Carcinoma / surgery. Female. Finland / epidemiology. Humans. Incidence. Male. Middle Aged. Neoplasm Staging. Parotid Neoplasms / epidemiology. Parotid Neoplasms / mortality. Parotid Neoplasms / surgery. Population Surveillance / methods. Survival Rate

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  • (PMID = 15880955.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
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52. Andreadis D, Epivatianos A, Poulopoulos A, Nomikos A, Papazoglou G, Antoniades D, Barbatis C: Detection of C-KIT (CD117) molecule in benign and malignant salivary gland tumours. Oral Oncol; 2006 Jan;42(1):57-65
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  • [Title] Detection of C-KIT (CD117) molecule in benign and malignant salivary gland tumours.
  • In the present study we analysed the expression of this molecule in salivary gland tumours.
  • Archival formalin-fixed, paraffin-embedded sections of 40 benign and 57 malignant salivary gland tumours were retrieved and retrospectively studied immunohistochemically using a polyclonal C-KIT antibody in an Envision/HRP technique.
  • In addition five samples of chronic submandibular sialadenitis, five normal minor salivary glands and parotid or submandibular gland tissue adjacent to benign tumour were also studied.
  • C-KIT expression was observed in cases of adenoid cystic, acinic cell polymorphous low grade, epithelial-myoepithelial, carcinosarcoma and basal cell adenocarcinomas, as in luminal cells of pleomorphic adenomas, in serous acinar and only in intercalated and a small number of striated ductal cells of inflammatory salivary gland tissue, whereas normal salivary lobules were generally negative except a weak positivity of intercalated cells.
  • Contrary to other reports, this study suggests that, C-KIT protein does not appear to be an exclusively specific marker for benign or malignant salivary gland neoplasms, but may be useful in differential diagnosis of adenoid cystic carcinoma from polymorphous low grade adenocarcinoma.
  • Furthermore its expression in serous acinar cells in sialadenitis and intercalated ductal cells in normal and inflammatory lesions may indicate a possible participation in pathogenesis of both neoplastic and non-neoplastic salivary gland diseases.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Adenoid Cystic / chemistry. Proto-Oncogene Proteins c-kit / analysis. Salivary Gland Neoplasms / chemistry

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  • (PMID = 16140564.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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53. Shapiro NL, Bhattacharyya N: Clinical characteristics and survival for major salivary gland malignancies in children. Otolaryngol Head Neck Surg; 2006 Apr;134(4):631-4
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  • [Title] Clinical characteristics and survival for major salivary gland malignancies in children.
  • OBJECTIVE: Determine presentation and survival rates for malignant pediatric salivary gland neoplasms.
  • METHODS: All cases of malignant neoplasms involving the parotid or submandibular gland in patients ages birth to 18 years were extracted from the Surveillance, Epidemiology, and End Results database (1988-2001).
  • RESULTS: 113 primary salivary gland malignancies (103 parotid, 10 submandibular) were identified.
  • Among parotid tumors, there were 44 (43%) mucoepidermoid carcinomas and 35 (34%) acinic cell carcinomas.
  • At a mean follow-up of 69.4 months, 6 (5.8%) patients with parotid malignancy were deceased; none of the submandibular malignancies were fatal.
  • Mean Kaplan-Meier survival for parotid gland lesions was 153 months, with rhabdomyosarcomas exhibiting significantly worse survivals as compared to other malignancies (P < 0.001, log-rank test).
  • CONCLUSIONS: Both epithelial and mesenchymal tumors present in the pediatric salivary gland.
  • Survival for both parotid and submandibular gland malignancies is good in children.
  • [MeSH-major] Carcinoma, Acinar Cell / mortality. Carcinoma, Mucoepidermoid / mortality. Salivary Gland Neoplasms / mortality

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  • (PMID = 16564387.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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54. Skálová A, Vanecek T, Sima R, Laco J, Weinreb I, Perez-Ordonez B, Starek I, Geierova M, Simpson RH, Passador-Santos F, Ryska A, Leivo I, Kinkor Z, Michal M: Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: a hitherto undescribed salivary gland tumor entity. Am J Surg Pathol; 2010 May;34(5):599-608
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: a hitherto undescribed salivary gland tumor entity.
  • We present a series of 16 salivary gland tumors with histomorphologic and immunohistochemical features reminiscent of secretory carcinoma of the breast.
  • This is a hitherto undescribed and distinctive salivary gland neoplasm, with features resembling both salivary acinic cell carcinoma (AciCC) and low-grade cystadenocarcinoma, and displaying strong similarities to breast secretory carcinoma.
  • For this tumor, we propose a designation mammary analogue secretory carcinoma of salivary glands (MASC).
  • Thirteen cases occurred in the parotid gland, and one each in the minor salivary glands of the buccal mucosa, upper lip, and palate.
  • This translocation was not found in any conventional salivary AciCC (12 cases), nor in other tumor types including pleomorphic adenoma (1 case) and low-grade cribriform cystadenocarcinoma (1 case), whereas ETV6-NTRK3 gene rearrangements were proven in all 3 tested cases of mammary secretory carcinoma.
  • [MeSH-major] Cystadenocarcinoma / genetics. Oncogene Proteins, Fusion / genetics. Salivary Gland Neoplasms / genetics

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  • [CommentIn] Am J Surg Pathol. 2011 Oct;35(10):1600-2 [21934478.001]
  • (PMID = 20410810.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / ETV6-NTRK3 fusion protein, human; 0 / Oncogene Proteins, Fusion; 0 / RNA, Neoplasm
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55. Leivo I, Jee KJ, Heikinheimo K, Laine M, Ollila J, Nagy B, Knuutila S: Characterization of gene expression in major types of salivary gland carcinomas with epithelial differentiation. Cancer Genet Cytogenet; 2005 Jan 15;156(2):104-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization of gene expression in major types of salivary gland carcinomas with epithelial differentiation.
  • Gene expression profiles were studied in 13 cases of salivary gland carcinoma including mucoepidermoid carcinoma (MEC), acinic cell carcinoma (ACC), and salivary duct carcinoma (SDC) using a cDNA array.
  • The small number of similarly deregulated genes in these carcinoma entities suggests an extensive genetic variation between them.
  • This result agrees with the great histopathological diversity of different entities of salivary gland carcinoma.
  • Furthermore, diversity in gene expression between the carcinoma types was identified also by hierarchical clustering.
  • Each carcinoma entity was clustered together but MEC, SDC, and ACC were separated from each other.
  • In MEC, overexpressed genes included those of cell proliferation (IL-6 and SFN) and cell adhesion (SEMA3F and COL6A3), whereas many underexpressed genes were related to DNA modification (NTHL1 and RBBP4).
  • An intermediate filament protein of basal epithelial cells, cytokeratin 14 (KRT14) was clearly differently expressed between the 3 types of carcinoma, and can be used as an aid in their differential diagnosis.
  • [MeSH-major] Epithelial Cells / pathology. Gene Expression Regulation, Neoplastic. Parotid Neoplasms / genetics. Salivary Gland Neoplasms / genetics


56. Craver RD, Fonseca P, Carr R: Pediatric epithelial salivary gland tumors: spectrum of histologies and cytogenetics at a children's hospital. Pediatr Dev Pathol; 2010 Sep-Oct;13(5):348-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric epithelial salivary gland tumors: spectrum of histologies and cytogenetics at a children's hospital.
  • There are conflicting reports regarding the relative frequency of benign and malignant epithelial salivary gland tumors in children.
  • A retrospective 14 year review of epithelial salivary gland tumors encountered at a children's hospital identified 13 tumors: 12 PAs and 1 acinic cell carcinoma (ACC).
  • Tumors arose in the parotid (7) and other sites (2 submandibular, 4 minor).
  • [MeSH-major] Adenoma, Pleomorphic / genetics. Adenoma, Pleomorphic / pathology. Salivary Gland Neoplasms / genetics. Salivary Gland Neoplasms / pathology

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  • (PMID = 20055685.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / HMGA2 Protein; 0 / PLAG1 protein, human
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57. Giannini PJ, Shetty KV, Horan SL, Reid WD, Litchmore LL: Adenoid cystic carcinoma of the buccal vestibule: A case report and review of the literature. Oral Oncol; 2006 Nov;42(10):1029-32
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  • [Title] Adenoid cystic carcinoma of the buccal vestibule: A case report and review of the literature.
  • Minor salivary gland tumors of the buccal vestibule are relatively rare.
  • Adenoid cystic carcinoma is the fifth most common salivary gland malignancy following mucoepidermoid carcinoma, adenocarcinoma not otherwise specified (NOS), acinic cell adenocarcinoma and polymorphous low-grade adenocarcinoma (PLGA).
  • Greater than half of adenoid cystic carcinomas occur in the parotid and submandibular glands.
  • Adenoid cystic carcinoma tends to have a protracted clinical course with wide infiltration and late distant metastases.
  • We present a case of an adenoid cystic carcinoma of the buccal vestibule in a 59-year-old Caucasian female patient that she had been aware of for 15 years.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Mouth Neoplasms / pathology. Salivary Gland Neoplasms / pathology


58. Aydin E, Turkoglu S, Ozen O, Akkuzu B: Mucinous cystadenocarcinoma of a minor salivary gland in the upper lip: case report. Auris Nasus Larynx; 2005 Sep;32(3):301-4
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  • [Title] Mucinous cystadenocarcinoma of a minor salivary gland in the upper lip: case report.
  • Mucinous cystadenocarcinoma of the salivary gland is a rare entity that has only recently been described.
  • Only a small proportion of salivary gland tumors are adenocarcinomas.
  • Most mucinous cystadenocarcinomas affect the major salivary glands, particularly the parotid.
  • The differential diagnosis includes mucoepidermoid carcinoma, acinic cell carcinoma, salivary duct carcinoma, nasal adenocarcinoma, and metastatic carcinoma.
  • The pathological diagnosis was low-grade mucinous cystadenocarcinoma of a minor salivary gland.
  • [MeSH-major] Cystadenocarcinoma, Mucinous / diagnosis. Cystadenocarcinoma, Mucinous / pathology. Lip / surgery. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / pathology

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  • (PMID = 15923100.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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59. Vacchi-Suzzi M, Bocciolini C, Bertarelli C, Dall'Olio D: Ki-67 proliferation rate as a prognostic marker in major salivary gland carcinomas. Ann Otol Rhinol Laryngol; 2010 Oct;119(10):677-83

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ki-67 proliferation rate as a prognostic marker in major salivary gland carcinomas.
  • OBJECTIVES: The study was performed to evaluate the prognostic relevance of cell proliferation associated with Ki-67/ Mib-1 immunostaining in malignant tumors of the major salivary glands.
  • METHODS: Cell proliferation was evaluated by Mib-1 antibody against Ki-67 antigen in 41 patients with cancer of the parotid or submandibular glands, including 14 acinic cell carcinomas, 12 ductal carcinomas, 7 mucoepidermoid carcinomas, 5 carcinomas ex pleomorphic adenoma, 1 adenoid cystic carcinoma, 1 undifferentiated carcinoma, and 1 polymorphous low-grade adenocarcinoma.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers / analysis. Carcinoma, Acinar Cell / mortality. Carcinoma, Adenoid Cystic / mortality. Carcinoma, Ductal / mortality. Carcinoma, Mucoepidermoid / mortality. Disease-Free Survival. Female. Humans. Immunohistochemistry. Male. Middle Aged. Parotid Neoplasms / mortality. Prognosis. Salivary Gland Neoplasms / mortality. Submandibular Gland Neoplasms / mortality

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  • (PMID = 21049853.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Ki-67 Antigen
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60. Boukheris H, Curtis RE, Land CE, Dores GM: Incidence of carcinoma of the major salivary glands according to the WHO classification, 1992 to 2006: a population-based study in the United States. Cancer Epidemiol Biomarkers Prev; 2009 Nov;18(11):2899-906
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence of carcinoma of the major salivary glands according to the WHO classification, 1992 to 2006: a population-based study in the United States.
  • Squamous cell (IR, 3.44) and mucoepidermoid (IR, 3.23) carcinomas occurred most frequently among males, whereas mucoepidermoid (IR, 2.67), acinic cell (IR, 1.57), and adenoid cystic (IR, 1.40) carcinomas were most common among females.
  • Mucoepidermoid, acinic cell, and adenoid cystic carcinomas predominated in females through age approximately 50 years; thereafter, IRs of acinic cell and adenoid cystic carcinomas were nearly equal among females and males, whereas IRs of mucoepidermoid carcinoma among males exceeded IRs among females (IRR, 1.57; 95% CI, 1.38-1.78).
  • Adenoid cystic carcinoma occurred equally in the submandibular and parotid glands, and other M-SGC histologic subtypes evaluated had 77% to 98% lower IRs in the submandibular gland.
  • [MeSH-major] Salivary Gland Neoplasms / classification. Salivary Gland Neoplasms / epidemiology

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  • (PMID = 19861510.001).
  • [ISSN] 1538-7755
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 CP010183-05
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS144622; NLM/ PMC2779732
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61. Jung YH, Hah JH, Sung MW, Kim KH: Parotidotomy approach for a midcheek mass: a new surgical strategy. Laryngoscope; 2010 Mar;120(3):495-9
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  • The parotid gland was fully bisected along the course of the zygomatic and buccal branches of the facial nerve to provide access to the midcheek mass.
  • The bisected parotid gland was repositioned after mass excision.
  • The parotidotomy approach was accomplished in two cases with a malignant tumor (one acinic cell carcinoma, one low-grade mucoepidermoid carcinoma), four with a benign tumor (two pleomorphic adenoma, one basal cell adenoma, one facial nerve schwannoma), and in one case with a chronic inflammatory lesion (chronic sialadenitis).

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  • (PMID = 20058313.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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