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1. Bansal M, Chaturvedi TP, Bansal R, Kumar M: Acanthomatous ameloblastoma of anterior maxilla. J Indian Soc Pedod Prev Dent; 2010 Jul-Sep;28(3):209-11

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acanthomatous ameloblastoma of anterior maxilla.
  • The unusual case of acanthomatous ameloblastoma occurring in maxillary left anterior region in a 13-year-old female child is presented with chief complaint of swelling in the upper left anterior region since one year and spacing between maxillary left central incisor and canine.
  • Microscopic examination of surgically excised specimen revealed solid epithelial cell nests with peripheral palisading ameloblastic cells and the central squamous cell assemblage that was consistent with the findings of acanthomatous ameloblastoma type.
  • Acanthomatous ameloblastoma is the extremely rare variant.
  • [MeSH-major] Ameloblastoma / pathology. Maxillary Neoplasms / pathology

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  • (PMID = 21157056.001).
  • [ISSN] 0970-4388
  • [Journal-full-title] Journal of the Indian Society of Pedodontics and Preventive Dentistry
  • [ISO-abbreviation] J Indian Soc Pedod Prev Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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2. Mayer MN, Anthony JM: Radiation therapy for oral tumors: canine acanthomatous ameloblastoma. Can Vet J; 2007 Jan;48(1):99-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiation therapy for oral tumors: canine acanthomatous ameloblastoma.
  • [MeSH-major] Acanthoma / veterinary. Ameloblastoma / veterinary. Dog Diseases / radiotherapy. Mouth Neoplasms / veterinary

  • MedlinePlus Health Information. consumer health - Oral Cancer.
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  • (PMID = 17310630.001).
  • [ISSN] 0008-5286
  • [Journal-full-title] The Canadian veterinary journal = La revue vétérinaire canadienne
  • [ISO-abbreviation] Can. Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Canada
  • [Number-of-references] 13
  • [Other-IDs] NLM/ PMC1716740
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3. Reed SD, Fulmer A, Buckholz J, Zhang B, Cutrera J, Shiomitsu K, Li S: Bleomycin/interleukin-12 electrochemogene therapy for treating naturally occurring spontaneous neoplasms in dogs. Cancer Gene Ther; 2010 Jul;17(7):457-64
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Intralesional bleomycin and feline interleukin-12 DNA (fIL-12 DNA) injection combined with translesional electroporation resulted in complete cure of two recurrent World Health Organization stage T(2b)N(0)M(0) oral squamous cell carcinomas (SCCs) and one T(2)N(0)M(0) acanthomatous ameloblastoma.
  • ECGT seems to be a safe and resulted in complete responses in SCC and acanthomatous ameloblastoma.

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  • (PMID = 20150931.001).
  • [ISSN] 1476-5500
  • [Journal-full-title] Cancer gene therapy
  • [ISO-abbreviation] Cancer Gene Ther.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA120895; United States / NCI NIH HHS / CA / 5R01 CA120895; United States / NCI NIH HHS / CA / R01 CA142855; United States / NCI NIH HHS / CA / CA142855-01; United States / NCI NIH HHS / CA / R01 CA142855-01; United States / NCI NIH HHS / CA / R01 CA098928
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 187348-17-0 / Interleukin-12
  • [Other-IDs] NLM/ NIHMS308695; NLM/ PMC3148143
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4. Britt LG, Middleton JR, Warhover TT, Kreeger JM, Branson KR: Acanthomatous ameloblastoma of the maxilla of an adult alpaca. Vet Radiol Ultrasound; 2005 Jan-Feb;46(1):65-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acanthomatous ameloblastoma of the maxilla of an adult alpaca.
  • An ameloblastoma was diagnosed histologically and palliative radiation therapy was attempted.
  • Necropsy findings confirmed an ameloblastoma of acanthomatous type.
  • [MeSH-major] Ameloblastoma / veterinary. Camelids, New World. Maxillary Neoplasms / veterinary

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  • (PMID = 15693563.001).
  • [ISSN] 1058-8183
  • [Journal-full-title] Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
  • [ISO-abbreviation] Vet Radiol Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Adebiyi KE, Ugboko VI, Omoniyi-Esan GO, Ndukwe KC, Oginni FO: Clinicopathological analysis of histological variants of ameloblastoma in a suburban Nigerian population. Head Face Med; 2006;2:42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological analysis of histological variants of ameloblastoma in a suburban Nigerian population.
  • BACKGROUND: This study was carried out to establish the relative incidence and provide clinico-pathologic information on the various histological types of ameloblastoma seen at the Obafemi Awolowo University Teaching Hospital complex, Ile-Ife in order to provide a baseline data which will be of significance to the pathologist and clinician.
  • METHODS: Clinico-pathologic data on a total of 77 histologically diagnosed cases of ameloblastoma archieved at the Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife over a 15 year period were obtained and analysed descriptively.
  • RESULTS: Follicular ameloblastoma was the most common histological type (50 cases, 64.9%), followed by plexiform ameloblastoma (10 cases, 13.0%).
  • 4 (5.2%) cases of desmoplastic and 3 (3.9%) cases of acanthomatous ameloblastoma were seen while the basal cell variant accounted for 2 (2.6%) cases.
  • Ameloblastoma occurred over an age range of 11 to 70 years with a peak age incidence in the 3rd decade.
  • CONCLUSION: This study provides a baseline data on variants of ameloblastoma as obtained in a suburban Nigerian population.
  • Since variants of ameloblastoma differ in biologic behaviour, the data collected in this study provides clinicopathologic information which is of significance to the pathologist and clinician.
  • [MeSH-major] Ameloblastoma / pathology. Jaw Neoplasms / pathology. Suburban Population

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  • (PMID = 17125498.001).
  • [ISSN] 1746-160X
  • [Journal-full-title] Head & face medicine
  • [ISO-abbreviation] Head Face Med
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1675998
  • [General-notes] NLM/ Original DateCompleted: 20070724
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6. Kelly JM, Belding BA, Schaefer AK: Acanthomatous ameloblastoma in dogs treated with intralesional bleomycin. Vet Comp Oncol; 2010 Jun;8(2):81-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acanthomatous ameloblastoma in dogs treated with intralesional bleomycin.
  • Acanthomatous ameloblastoma (AA) is a benign gingival tumour that often invades bone.
  • [MeSH-major] Ameloblastoma / veterinary. Antibiotics, Antineoplastic / therapeutic use. Bleomycin / therapeutic use. Dog Diseases / drug therapy. Gingival Neoplasms / veterinary

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  • (PMID = 20579320.001).
  • [ISSN] 1476-5829
  • [Journal-full-title] Veterinary and comparative oncology
  • [ISO-abbreviation] Vet Comp Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 11056-06-7 / Bleomycin
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7. Siar CH, Nakano K, Ng KH, Tomida M, Nagatsuka H, Kawakami T: Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1. Eur J Med Res; 2010 Apr 8;15(4):180-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histopathologically, SOT can be easily misdiagnosed as an acanthomatous ameloblastoma.

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  • (PMID = 20554499.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Calcium-Binding Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / NOTCH1 protein, human; 0 / NOTCH3 protein, human; 0 / NOTCH4 protein, human; 0 / Proto-Oncogene Proteins; 0 / Receptor, Notch1; 0 / Receptors, Notch; 0 / delta protein; 134324-36-0 / Serrate proteins
  • [Other-IDs] NLM/ PMC3401003
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8. Murray RL, Aitken ML, Gottfried SD: The use of rim excision as a treatment for canine acanthomatous ameloblastoma. J Am Anim Hosp Assoc; 2010 Mar-Apr;46(2):91-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The use of rim excision as a treatment for canine acanthomatous ameloblastoma.
  • This study reviews rim excision as a treatment for canine acanthomatous ameloblastomas (CAA) in dogs with <3 mm of bone involvement.
  • [MeSH-major] Ameloblastoma / veterinary. Dog Diseases / surgery. Gingival Neoplasms / veterinary

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  • (PMID = 20194363.001).
  • [ISSN] 1547-3317
  • [Journal-full-title] Journal of the American Animal Hospital Association
  • [ISO-abbreviation] J Am Anim Hosp Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Atalay B, Soluk M, Brkić A, Emes Y, Cetin O, Olgac V: Desmoplastic ameloblastoma. J Craniofac Surg; 2009 Nov;20(6):2256-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic ameloblastoma.
  • Ameloblastoma is a rare benign odontogenic epithelial tumor characterized by abnormal cell growth, which easily infiltrates and destroys surrounding bony tissues.
  • One of the 3 clinical variants of ameloblastoma is desmoplastic type, with involvement of the maxillary arch more often than the mandible.
  • Its histopathologic variant characterized by extensive squamous metaplasia, islands of tumor cells, and sometimes keratin formation is known as desmoplastic acanthomatous ameloblastoma.The aim of this report was to present an unusual case of symphysis located desmoplastic acanthomatous ameloblastoma in a 56-year-old female patient, who was experiencing laryngeal carcinoma 2 years ago.
  • [MeSH-major] Ameloblastoma / pathology. Mandibular Neoplasms / pathology. Neoplasms, Second Primary / pathology

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  • (PMID = 19934686.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Brooks JK, Al-Mubarak H, Ribera MJ, Cohen PD, Ross DS, Scheper MA: Diminutive, interradicular "hybrid" desmoplastic/acanthomatous ameloblastoma. Quintessence Int; 2010 Mar;41(3):209-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diminutive, interradicular "hybrid" desmoplastic/acanthomatous ameloblastoma.
  • This article reports an atypical case of a small, painful ameloblastoma arising between the roots of the mandibular left canine and lateral incisor in a 66-year-old female.
  • Histopathology revealed a "hybrid" ameloblastoma with a pronounced desmoplastic pattern and acanthomatous changes.
  • [MeSH-major] Ameloblastoma / pathology. Mandibular Neoplasms / pathology

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  • (PMID = 20213021.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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11. Force J: Diagnostic imaging in veterinary dental practice. Canine acanthomatous ameloblastoma. J Am Vet Med Assoc; 2009 Nov 1;235(9):1045-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic imaging in veterinary dental practice. Canine acanthomatous ameloblastoma.
  • [MeSH-major] Acanthoma / veterinary. Ameloblastoma / veterinary. Diagnostic Imaging / veterinary. Dog Diseases / diagnosis

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  • (PMID = 19878000.001).
  • [ISSN] 0003-1488
  • [Journal-full-title] Journal of the American Veterinary Medical Association
  • [ISO-abbreviation] J. Am. Vet. Med. Assoc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Martano M, Damiano S, Restucci B, Paciello O, Russo V, Maiolino P: Nuclear morphometry in canine acanthomatous ameloblastomas and squamous cell carcinomas. Eur J Histochem; 2006 Apr-Jun;50(2):125-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nuclear morphometry in canine acanthomatous ameloblastomas and squamous cell carcinomas.
  • The aim of this study was to evaluate whether morphometrical analysis can be of diagnostic value for canine acanthomatous ameloblastoma.
  • We calculated, by means of an automated image analyser, some morphometric nuclear parameters, in particular: mean nuclear area (MNA), mean nuclear perimeter (MNP), maximum and minimum diameters (MDx and MDm) coefficient of variation of the nuclear area (NACV), largest to smallest dimension ratio (LS ratio), and form factor (FF), in 8 canine acanthomatous ameloblastomas, and we compared these morphometric data to those of 13 squamous cell carcinomas of canine gingiva.
  • The results indicated a progressive increase of the MNA, NACV, MNP and MDm proceeding from acanthomatous ameloblastomas (MNA: 42.11+/-8.74; NACV: 28,36+/-7,23; MNP: 24.18+/- 2.68; MDm: 5.69+/-0.49) to squamous cell carcinomas (MNA:49,69+/-9,10; NACV: 30,89+/-7,75; MNP: 25.63+/-2.54; MDm: 6.64+/-0.73).
  • On the contrary, the LS ratio and the FF resulted greater in acanthomatous ameloblastomas (LS ratio: 1,63+/-0,12; FF: 1,13+/-0,002) than in SCCs (LS ratio: 1,40+/-0,12; FF:0.91+/-0.38).
  • Moreover, the MNA, MNP,MDx and MDm resulted similar (MNA: p=0.89; MNP: p=0,65; MDm: p=0,16; MDx: p=0,13) in a subset of four acanthomatous ameloblastomas with cellular atypia (MNA:49,01+/-6,88; MNP: 26,28+/-1,99; MDm: 6.08+/-0.41; MDx: 10.18+/-0.88) and in squamous cell carcinomas (MNA:49.69+/-9,10; MNP: 25.63+/-2.54; MDm: 6.64+/-0.73; MDx: 9.26+/-1.05).
  • While the NACV values resulted higher in typical acanthomatous ameloblastoma (29,99+/-6,06) than in atypical acanthomatous ameloblastoma (26,74+/-8,84) and similar to those of the SCCs (30,89+/-7,75).
  • These results seem to confirm that acanthomatous ameloblastoma is a malignant or potentially malignant lesion and emphasizes that nuclear morphometry analysis can be an useful diagnostic and prognostic method in canine oral pathology.
  • [MeSH-major] Ameloblastoma / veterinary. Carcinoma, Squamous Cell / veterinary. Cell Nucleus / pathology. Dog Diseases / diagnosis. Gingiva / pathology. Jaw Neoplasms / veterinary

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  • (PMID = 16864123.001).
  • [ISSN] 1121-760X
  • [Journal-full-title] European journal of histochemistry : EJH
  • [ISO-abbreviation] Eur J Histochem
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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13. Reed SD, Fulmer A, Buckholz J, Zhang B, Cutrera J, Shiomitsu K, Li S: Bleomycin/interleukin-12 electrochemogenetherapy for treating naturally occurring spontaneous neoplasms in dogs. Cancer Gene Ther; 2010 Aug;17(8):571-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Intralesional bleomycin (BLM) and feline interleukin-12 DNA injection combined with translesional electroporation resulted in complete cure of two recurrent World Health Organization stage T(2b)N(0)M(0) oral squamous cell carcinomas (SCCs) and one T(2)N(0)M(0) acanthomatous ameloblastoma.
  • ECGT seems to be a safe and resulted in complete responses in SCC and acanthomatous ameloblastoma.

  • MedlinePlus Health Information. consumer health - Genes and Gene Therapy.
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  • Hazardous Substances Data Bank. BLEOMYCIN .
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  • [RetractionIn] Cancer Gene Ther. 2010 Nov;17(11):826 [20953214.001]
  • (PMID = 20414325.001).
  • [ISSN] 1476-5500
  • [Journal-full-title] Cancer gene therapy
  • [ISO-abbreviation] Cancer Gene Ther.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA098928; United States / NCI NIH HHS / CA / R01 CA142855; United States / NCI NIH HHS / CA / 5R01CA120895; United States / PHS HHS / / T-32
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Retracted Publication
  • [Publication-country] England
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 187348-17-0 / Interleukin-12; 9007-49-2 / DNA
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14. Fujita S, Seki S, Fujiwara M, Ikeda T: Midkine expression correlating with growth activity and tooth morphogenesis in odontogenic tumors. Hum Pathol; 2008 May;39(5):694-700

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ameloblastoma showed MK localization in the peripheral columnar cells in budding processes from the parenchyma, which frequently expressed proliferating cell nuclear antigen.
  • MK was also preferentially expressed in keratinized cells in acanthomatous ameloblastoma and keratocystic odontogenic tumor.
  • [MeSH-minor] Adolescent. Adult. Aged. Ameloblastoma / pathology. Ameloblastoma / physiopathology. Female. Humans. Male. Middle Aged. Odontoma / pathology. Odontoma / physiopathology

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  • (PMID = 18329695.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MDK protein, human; 0 / Nerve Growth Factors
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15. Krishnapillai R, Angadi PV: A clinical, radiographic, and histologic review of 73 cases of ameloblastoma in an Indian population. Quintessence Int; 2010 May;41(5):e90-100

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A clinical, radiographic, and histologic review of 73 cases of ameloblastoma in an Indian population.
  • The present study was undertaken to retrospectively compare the clinical, radiologic, and histopathologic features of 73 cases of ameloblastoma in Indians.
  • METHOD AND MATERIALS: Biopsy records of 73 histologically diagnosed cases of ameloblastoma over an 18-year period were retrieved and analyzed for age, sex, site distribution, clinical presentation, radiologic features, and histopathology.
  • RESULTS: Ameloblastoma accounted for 60.3% of all odontogenic tumors in this study, with a mean age of presentation of 30.2 years.
  • Radiologically, ameloblastoma presented as either unilocular or multilocular radiolucency, with a significant age difference noted between unilocular and multilocular lesions.
  • The most common histologic type in contrast to other studies was unicystic ameloblastoma followed by follicular and acanthomatous ameloblastoma.
  • Recurrence was seen in 13.3% of patients, predominantly in males, in the molar-ramus area, and the common histologic type was follicular ameloblastoma followed by unicystic ameloblastoma.
  • CONCLUSION: The finding of unicystic ameloblastoma being the second most common recurrent variant of ameloblastoma, especially when associated with cyst wall invasion or intramural proliferation, may warrant a more aggressive treatment than traditional enucleation/curettage for this entity to prevent recurrence.
  • [MeSH-major] Ameloblastoma / pathology. Jaw Neoplasms / pathology

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  • (PMID = 20376369.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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16. Madarame H, Enaga S: Peripheral acanthomatous ameloblasoma in a rabbit with review of previous submissions of the Armed Forces Institute of Pathology Wednesday Slide Conference. J Vet Med Sci; 2009 Jul;71(7):987-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peripheral acanthomatous ameloblasoma in a rabbit with review of previous submissions of the Armed Forces Institute of Pathology Wednesday Slide Conference.
  • A case of peripheral acanthomatous ameloblasoma of the angulus orisa in a 6-year-old female rabbit was described.
  • Acanthomatous ameloblasoma in the submucosa of the angulus orisa has not been described and it may develop from an ectopic rest of odontogenic tissue.

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  • (PMID = 19652491.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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17. Correnti M, Rossi M, Avila M, Perrone M, Rivera H: Human papillomavirus in ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Sep;110(3):e20-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Human papillomavirus in ameloblastoma.
  • Of the histological variants, the plexiform represented 3 (17%) of the 18, 2 (11%) were follicular, 2 (11%) were acanthomatous, and 1 (6%) was desmoplastic.
  • [MeSH-major] Alphapapillomavirus / isolation & purification. Ameloblastoma / virology. Mandibular Neoplasms / virology. Papillomavirus Infections / diagnosis

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20727492.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral
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18. Huang IY, Lai ST, Chen CH, Chen CM, Wu CW, Shen YH: Surgical management of ameloblastoma in children. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Oct;104(4):478-85

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of ameloblastoma in children.
  • OBJECTIVE: The purpose of this study was to report experience in the treatment of ameloblastoma in Taiwanese children and to discuss the treatment regimen.
  • STUDY DESIGN: Fifteen patients, all younger than 18 years of age, with a diagnosis of ameloblastoma in our department between January 1991 and December 2004 were selected for study.
  • Of the histologic types, 5 were plexiform, 3 were mixed type, and 3 were acanthomatous type.
  • CONCLUSIONS: Good results can be achieved in the treatment of ameloblastoma in children using conservative surgery.
  • [MeSH-major] Ameloblastoma / surgery. Mandibular Neoplasms / surgery. Oral Surgical Procedures / methods

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  • (PMID = 17524681.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Punnya AV, Rekha K: "Ameloblastoma with mucous cells": review of literature and presentation of 2 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Dec;106(6):e20-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] "Ameloblastoma with mucous cells": review of literature and presentation of 2 cases.
  • Ameloblastoma, a relatively rare benign odontogenic tumor; originates from the odontogenic epithelium and has been studied extensively for its unique clinicopathologic features.
  • It usually exhibits a range of histopathologic features, such as follicular, plexiform, acanthomatous, granular, basal cell, and desmoplastic variants, which are well recognized.
  • The occurrence of mucous cells in ameloblastoma is an exceptionally rare phenomenon and to date only 4 well established cases have been reported.
  • In the present paper, 2 more cases of ameloblastoma showing evidence of mucous cells are reported, along with a review of pertinent literature.
  • A brief clinicopathologic analysis of all the reported cases, an insight into possible histogenesis of these cells in ameloblastoma, and diagnostic difficulties encountered due to this finding are also discussed.
  • An interesting finding in our review is that all of the the cases of ameloblastoma exhibiting mucous cells occurred in the anterior region of the jaw with a predilection to mandible.
  • [MeSH-major] Ameloblastoma / pathology. Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology

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  • (PMID = 19000605.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucins
  • [Number-of-references] 28
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20. Barboza CA, Pereira Pinto L, Freitas Rde A, Costa Ade L, Souza LB: Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor. Braz Dent J; 2005;16(1):56-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor.
  • In this study, proliferating cell nuclear antigen (PCNA) and p53 protein expressions were analyzed in 16 cases of ameloblastoma and 8 cases of adenomatoid odontogenic tumor (AOT).
  • The cases of ameloblastoma consisted of solid type tumors and histologic arrangements of different subtypes were observed.
  • The odontogenic tumors were grouped as follows: follicular ameloblastoma (n=7), plexiform ameloblastoma (n=4), acanthomatous + follicular ameloblastoma (n=3), basal cell ameloblastoma (n=2), adenomatoid odontogenic tumor (n=8).
  • PCNA immunohistochemical expression revealed stronger quantitative labeling index for the follicular ameloblastoma, while for p53 protein the strongest quantitative labeling index was detected in the plexiform type.
  • Nevertheless, statistical analysis using ANOVA and Tukey's test did not detect significant differences (p>0.05) among the histologic subtypes of ameloblastoma.
  • The findings of this study suggest that the different histologic patterns of ameloblastoma did not show a direct correlation with their clinical behavior and consequently with the prognosis of the cases.
  • The results also indicated that the ameloblastoma has greater proliferative potential than the AOT, which can contribute to explain its more aggressive and invasive characteristics.
  • [MeSH-major] Ameloblastoma / metabolism. Odontogenic Tumors / metabolism. Proliferating Cell Nuclear Antigen / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis

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  • (PMID = 16113935.001).
  • [ISSN] 0103-6440
  • [Journal-full-title] Brazilian dental journal
  • [ISO-abbreviation] Braz Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / Tumor Suppressor Protein p53
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21. Dennis MS, Rudnick EF, Giashuddin S, Powers CN, Reiter ER: Pathology quiz case. Ameloblastoma, acanthomatous type. Arch Otolaryngol Head Neck Surg; 2007 Nov;133(11):1167-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathology quiz case. Ameloblastoma, acanthomatous type.
  • [MeSH-major] Ameloblastoma / pathology. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 18025326.001).
  • [ISSN] 0886-4470
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Cairns L, Naidu A, Robinson CM, Sloan P, Wright JM, Hunter KD: CD56 (NCAM) expression in ameloblastomas and other odontogenic lesions. Histopathology; 2010 Oct;57(4):544-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of this study was to describe the expression of CD56 in odontogenic lesions with particular reference to the differential diagnosis of ameloblastoma and odontogenic keratocyst.
  • Immunoreactivity was lost in areas of inflammation, acanthomatous differentiation, in areas of cystic change and upon fusion with overlying surface epithelium.
  • CONCLUSIONS:   CD56 expression in odontogenic epithelium is highly suggestive of ameloblastoma and can help in differentiating this from odontogenic keratocyst.
  • [MeSH-major] Ameloblastoma / metabolism. Antigens, CD56 / biosynthesis. Odontogenic Tumors / metabolism

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  • [Copyright] © 2010 Blackwell Publishing Limited.
  • (PMID = 20875069.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD56; 0 / Biomarkers, Tumor; 0 / NCAM1 protein, human
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23. Kumamoto H, Ooya K: Immunohistochemical detection of BH3-only proteins in ameloblastic tumors. Oral Dis; 2008 Sep;14(6):550-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acanthomatous ameloblastomas showed no reactivity for Bid, Bim, Bad, Noxa, or Puma in keratinizing cells, whereas granular cells in granular cell ameloblastomas reacted with these BH3-only proteins.
  • Distinctive expression patterns of these BH3-only proteins in ameloblastoma variants suggest that the BH3-only proteins might be involved in tumor cell differentiation of ameloblastomas.
  • [MeSH-major] Ameloblastoma / pathology. Apoptosis Regulatory Proteins / analysis. Proto-Oncogene Proteins c-bcl-2 / analysis

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  • (PMID = 18826384.001).
  • [ISSN] 1601-0825
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / BAD protein, human; 0 / BBC3 protein, human; 0 / BH3 Interacting Domain Death Agonist Protein; 0 / BID protein, human; 0 / Bcl-2-like protein 11; 0 / Membrane Proteins; 0 / PMAIP1 protein, human; 0 / Proto-Oncogene Proteins; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / bcl-Associated Death Protein; 68238-35-7 / Keratins
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24. Kumamoto H, Ohki K, Ooya K: Expression of p63 and p73 in ameloblastomas. J Oral Pathol Med; 2005 Apr;34(4):220-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Immunoreactivity for p63 and p73 was evident in epithelial cells neighboring the basement membrane in developing and neoplastic odontogenic tissues. p63 expression in desmoplastic ameloblastomas was significantly higher than in acanthomatous and granular cell ameloblastomas, and ameloblastic carcinomas showed higher p63 expression than metastasizing ameloblastomas. p73 expression was significantly higher in plexiform ameloblastomas than in follicular ameloblastomas, and basal cell ameloblastomas showed higher p73 expression than granular cell ameloblastomas. mRNA transcripts for Delta Np63 and TAp73 were detected in all developing and neoplastic odontogenic tissues.
  • TAp63 mRNA was expressed in five of eight tooth germs, 16 of 34 ameloblastomas, and one of one malignant ameloblastoma, whereas Delta Np73 mRNA was recognized in one of eight tooth germs, nine of 34 ameloblastomas, and one of one malignant ameloblastoma.
  • [MeSH-major] Ameloblastoma / genetics. Apoptosis / genetics. DNA-Binding Proteins / genetics. Genes, Tumor Suppressor. Nuclear Proteins / genetics. Phosphoproteins / genetics. Trans-Activators / genetics. Tumor Suppressor Proteins / genetics

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  • (PMID = 15752257.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Nuclear Proteins; 0 / Phosphoproteins; 0 / Protein Isoforms; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Protein p53; 0 / Tumor Suppressor Proteins; 0 / tumor suppressor protein p73
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25. Kumamoto H, Ooya K: Immunohistochemical detection of beta-catenin and adenomatous polyposis coli in ameloblastomas. J Oral Pathol Med; 2005 Aug;34(7):401-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Follicular ameloblastomas and acanthomatous ameloblastomas tended to show high nuclear beta-catenin expression and low APC reactivity, as compared with other ameloblastoma variants.
  • [MeSH-major] Adenomatous Polyposis Coli Protein / analysis. Ameloblastoma / chemistry. Cytoskeletal Proteins / analysis. Jaw Neoplasms / chemistry. Trans-Activators / analysis

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  • (PMID = 16011608.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Adenomatous Polyposis Coli Protein; 0 / CTNNB1 protein, human; 0 / CTNNB1 protein, mouse; 0 / Cytoskeletal Proteins; 0 / Trans-Activators; 0 / beta Catenin
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26. Leocata P, Villari D, Fazzari C, Lentini M, Fortunato C, Nicòtina PA: Syndecan-1 and Wingless-type protein-1 in human ameloblastomas. J Oral Pathol Med; 2007 Aug;36(7):394-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: SDC1 and Wnt1 expressions were investigated in 29 ameloblastoma subtypes and seven tooth buds.
  • It also showed epithelial tumour cells in the acanthomatous and plexiform subtypes, and it often occurred in stellate reticulum cells and basal ameloblasts of tooth buds.
  • [MeSH-major] Ameloblastoma / pathology. Syndecan-1 / analysis. Wnt1 Protein / analysis

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  • (PMID = 17617831.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / SDC1 protein, human; 0 / Syndecan-1; 0 / WNT1 protein, human; 0 / Wnt1 Protein
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27. Fulco GM, Nonaka CF, Souza LB, Miguel MC, Pinto LP: Solid ameloblastomas - Retrospective clinical and histopathologic study of 54 cases. Braz J Otorhinolaryngol; 2010 Mar-Apr;76(2):172-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Recently, the World Health Organization (WHO) excluded the desmoplastic pattern from the histopathological spectrum of solid ameloblastomas and classified it as a distinct variant, named desmoplastic ameloblastoma.
  • The most frequent histological patterns in solid ameloblastomas were follicular (77.6%), acanthomatous (69.4%), and plexiform (65.3%).
  • [MeSH-major] Ameloblastoma / pathology. Jaw Neoplasms / pathology

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  • (PMID = 20549076.001).
  • [ISSN] 1808-8686
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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28. Kumamoto H, Ooya K: Expression of bone morphogenetic proteins and their associated molecules in ameloblastomas and adenomatoid odontogenic tumors. Oral Dis; 2006 Mar;12(2):163-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acanthomatous ameloblastomas showed increased BMP-7 reactivity in keratinizing cells.
  • [MeSH-major] Ameloblastoma / pathology. Bone Morphogenetic Proteins / analysis. Odontogenic Tumors / pathology

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  • (PMID = 16476038.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / BMP2 protein, human; 0 / BMP4 protein, human; 0 / BMP7 protein, human; 0 / Bone Morphogenetic Protein 2; 0 / Bone Morphogenetic Protein 4; 0 / Bone Morphogenetic Protein 7; 0 / Bone Morphogenetic Proteins; 0 / Core Binding Factor Alpha 1 Subunit; 0 / Sp7 protein, human; 0 / Transcription Factors; 0 / Transforming Growth Factor beta; EC 2.7.11.30 / Bone Morphogenetic Protein Receptors, Type I; EC 2.7.11.30 / Bone Morphogenetic Protein Receptors, Type II
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29. González-Alva P, Tanaka A, Oku Y, Miyazaki Y, Okamoto E, Fujinami M, Yoshida N, Kikuchi K, Ide F, Sakashita H, Kusama K: Enhanced expression of podoplanin in ameloblastomas. J Oral Pathol Med; 2010 Jan;39(1):103-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Immunoreactivity for E-cadherin was weak or negative in keratinizing cells of acanthomatous AMs, suggesting terminal differentiation of the tumor cells.
  • [MeSH-major] Ameloblastoma / pathology. Membrane Glycoproteins / analysis

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  • (PMID = 19691459.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Cadherins; 0 / Membrane Glycoproteins; 0 / PDPN protein, human; 0 / Vimentin
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30. Kumamoto H, Ooya K: Detection of mitochondria-mediated apoptosis signaling molecules in ameloblastomas. J Oral Pathol Med; 2005 Oct;34(9):565-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Keratinizing cells in acanthomatous ameloblastomas and granular cells in granular cell ameloblastomas showed a decrease or loss of immunoreactivity for these mitochondria-mediated apoptosis signaling molecules.
  • [MeSH-major] Ameloblastoma / pathology. Apoptosis / physiology. Intracellular Signaling Peptides and Proteins / analysis. Mitochondria / physiology. Signal Transduction / physiology

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  • (PMID = 16138896.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / AIFM1 protein, human; 0 / APAF1 protein, human; 0 / Apoptosis Inducing Factor; 0 / Apoptotic Protease-Activating Factor 1; 0 / Flavoproteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / Proteins; 9007-43-6 / Cytochromes c; EC 3.4.22.- / CASP9 protein, human; EC 3.4.22.- / Caspase 9; EC 3.4.22.- / Caspases
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31. Kumamoto H, Ooya K: Immunohistochemical detection of phosphorylated Akt, PI3K, and PTEN in ameloblastic tumors. Oral Dis; 2007 Sep;13(5):461-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Plexiform ameloblastomas showed significantly higher expression of PI3K than follicular ameloblastomas, and PI3K immunoreactivity in ameloblastomas without cellular variation was significantly higher than that in acanthomatous ameloblastomas.
  • [MeSH-major] Ameloblastoma / chemistry. Jaw Neoplasms / chemistry. Membrane Proteins / analysis. Oncogene Protein v-akt / analysis. PTEN Phosphohydrolase / analysis

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  • (PMID = 17714348.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Membrane Proteins; EC 2.7.11.1 / Oncogene Protein v-akt; EC 3.1.3.48 / TPTE protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
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32. Kumamoto H, Ooya K: Immunohistochemical detection of MT1-MMP, RECK, and EMMPRIN in ameloblastic tumors. J Oral Pathol Med; 2006 Jul;35(6):345-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Follicular ameloblastomas showed significantly lower expression of RECK than plexiform ameloblastomas, and immunoreactivity for RECK in acanthomatous ameloblastomas was slightly lower than that in other cellular variants.
  • [MeSH-major] Ameloblastoma / chemistry. Antigens, CD147 / analysis. Jaw Neoplasms / chemistry. Matrix Metalloproteinases / analysis. Membrane Glycoproteins / analysis. Tooth Germ / chemistry

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  • (PMID = 16762015.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / RECK protein, human; 136894-56-9 / Antigens, CD147; EC 3.4.24.- / Matrix Metalloproteinases; EC 3.4.24.- / Matrix Metalloproteinases, Membrane-Associated
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33. Kumamoto H, Ooya K: Immunohistochemical detection of phosphorylated JNK, p38 MAPK, and ERK5 in ameloblastic tumors. J Oral Pathol Med; 2007 Oct;36(9):543-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Expression of p-p38 MAPK was found in epithelial or neoplastic cells in tooth germs and ameloblastic tumors except for two ameloblastomas, and increased expression was found in keratinizing cells of acanthomatous ameloblastomas.
  • [MeSH-major] Ameloblastoma / enzymology. Jaw Neoplasms / enzymology. Mitogen-Activated Protein Kinases / metabolism. Tooth Germ / enzymology

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  • (PMID = 17850438.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] EC 2.7.11.24 / JNK Mitogen-Activated Protein Kinases; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 7; EC 2.7.11.24 / Mitogen-Activated Protein Kinases; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases
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