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1. Honigmann P, Walz A, Bussmann C, Lerf B: Spontaneous bleeding of an Abrikossoff's tumor--a case report. J Cardiothorac Surg; 2009;4:57

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous bleeding of an Abrikossoff's tumor--a case report.
  • Abrikossoff tumors are a rare tumor entity.
  • The initial CT-scan revealed a solid tumor mass in the right lower bronchus.
  • [MeSH-major] Bronchial Neoplasms / surgery. Granular Cell Tumor / surgery. Hemothorax / surgery. Pneumonectomy / methods

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  • (PMID = 19860925.001).
  • [ISSN] 1749-8090
  • [Journal-full-title] Journal of cardiothoracic surgery
  • [ISO-abbreviation] J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2774303
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2. Meling TR, Fridrich K, Evensen JF, Nedregaard B: Malignant granular cell tumor of the skull base. Skull Base; 2008 Jan;18(1):59-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant granular cell tumor of the skull base.
  • OBJECTIVE AND IMPORTANCE: Malignant granular cell tumors (MGCTs) are extremely rare, high-grade sarcomas of Schwann cell origin.
  • Magnetic resonance imaging (MRI) showed a 5-cm bone-eroding suboccipital tumor and a second tumor, anterocaudal to this, 4 cm in diameter.
  • A 4-cm multinodular tumor was removed, freeing it from the internal jugular vein.
  • A 5-cm suboccipital tumor infiltrated the trapezius, semispinalis capitis, and longissimus capitis muscles.
  • The major and minor rectus capitis muscles were completely engulfed by tumor and their attachments to the occipital bone completely eroded.
  • These muscles were resected with a free margin to remove all tumor tissue.
  • We then removed tumor encasing the right vertebral artery, the medial mastoid process up to the transverse sinus and anteriorly to the stylomastoid foramen, and lastly, the posterior third of the occipital condyle, achieving a gross total removal and no visible residual on postoperative contrast-enhanced MRI.

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  • (PMID = 18592017.001).
  • [ISSN] 1531-5010
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2435465
  • [Keywords] NOTNLM ; Granular cell tumor / malignant / skull base / surgery
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3. Randjelović TD, Stojsić ZM, Gacić JM, Babić DN, Stojiljković MT, Baralić IM, Granić MK, Ivanović NS, Gacić DM: [Multifocal Abrikossoff's granular cell tumour of the oesophagus--case report]. Srp Arh Celok Lek; 2008 Sep-Oct;136(9-10):533-7
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  • [Title] [Multifocal Abrikossoff's granular cell tumour of the oesophagus--case report].
  • INTRODUCTION: Granular cell tumours, relatively uncommon soft tissue tumours, have been a matter of debate among pathologists regarding histogenesis for a long time.
  • CT scan of the chest confirmed luminal narrowing owing to the tumour of the upper oesophagus.
  • A primary biopsy specimen taken from the largest nodules confirmed an unusual pathological finding of the granular cell tumour.
  • The operative specimen consisted of four ovoid tumours alongside the oesophagus (the greatest diameter 0.5-1.8, average 1.25).
  • All verified tumours histologicaly consisted of a spindle-shaped or polygonal cells containing small and large eosinophilic granules and central nuclei.
  • Most tumour cells showed strongly positive immunohistochemical staining for S-100 protein.
  • These tumour cells were partially positive for p-53 and Ki-67.
  • CONCLUSION: Multifocal granular cell tumour of the oesophagus is an unusual finding with low incidence, and rarely caused symptoms.
  • Pathological features and multiplicity of such tumours emphasized malignant predisposition requiring surgical resection of the oesophagus.
  • [MeSH-major] Esophageal Neoplasms / diagnosis. Granular Cell Tumor / diagnosis. Neoplasms, Multiple Primary / diagnosis

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  • (PMID = 19069347.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia
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4. Arai E, Nishida Y, Tsukushi S, Sugiura H, Ishiguro N: Intramuscular granular cell tumor in the lower extremities. Clin Orthop Relat Res; 2010 May;468(5):1384-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramuscular granular cell tumor in the lower extremities.
  • Granular cell tumors are uncommon but typically histologically benign neoplasms that occasionally behave as malignant tumors.
  • Differentiation of benign granular cell tumors from malignant counterparts with radiographic and/or histologic analysis is crucial for physicians.
  • We retrospectively studied five cases of intramuscular granular cell tumors arising in the lower extremities.
  • All tumors had been histologically diagnosed as benign and were resected with a wide surgical margin.
  • Intramuscular granular cell tumors can be diagnosed based on their characteristic MRI features, such as peripheral high intensity on T2-weighed images, and histologic evaluation.
  • The histologic criteria described by Fanburg-Smith et al. can differentiate malignant granular cell tumors from benign tumors.
  • A wide resection seems suitable for most granular cell tumors in the extremities.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Leg
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Prognosis. Retrospective Studies. Time Factors

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  • (PMID = 19760336.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2853648
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5. Eandi JA, Asuncion A, Vandewalker KN, Javidan J: Granular cell tumor of the urinary bladder with pseudoepitheliomatous hyperplasia and colocalization with adenocarcinoma. Int J Urol; 2007 Sep;14(9):862-4
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  • [Title] Granular cell tumor of the urinary bladder with pseudoepitheliomatous hyperplasia and colocalization with adenocarcinoma.
  • Granular cell tumor of the bladder is exceptionally rare, with only 11 cases reported in the published reports.
  • Pseudoepitheliomatous hyperplasia of the overlying squamous epithelium has been observed in non-bladder granular cell tumors.
  • We herein report the first case of bladder granular cell tumor to exhibit pseudoepitheliomatous hyperplasia.
  • This phenomenon is significant as it may potentially lead to difficulty in the distinction between infiltrative squamous cell carcinoma and pseudoepitheliomatous hyperplasia in cases of granular cell tumor of the bladder.
  • This case also represents the first granular cell tumor to demonstrate colocalization with adenocarcinoma of the bladder.
  • Based on our findings and a review of the published reports, management for granular cell tumor of the bladder should involve a course of local resection combined with active surveillance given its typical benign course, albeit with the potential for local recurrence.
  • [MeSH-major] Adenocarcinoma / pathology. Granular Cell Tumor / pathology. Neoplasms, Multiple Primary / pathology. Urinary Bladder Neoplasms / pathology

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  • (PMID = 17760758.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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6. Perçinel S, Savaş B, Yilmaz G, Erinanç H, Küpana Ayva S, Bektaş M, Ensari A: Granular cell tumor of the esophagus: three case reports and review of the literature. Turk J Gastroenterol; 2008 Sep;19(3):184-8
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  • [Title] Granular cell tumor of the esophagus: three case reports and review of the literature.
  • The esophagus is the most common site of origin of gastrointestinal tract granular cell tumors.
  • Approximately 270 cases of esophageal granular cell tumors have been reported in the literature.
  • Most esophageal granular cell tumors are found incidentally during endoscopy.
  • Although granular cell tumor of the esophagus has become easily recognizable by its endoscopic features, it has to be differentiated from other benign and malignant mucosal and submucosal lesions.
  • The majority of esophageal granular cell tumors are asymptomatic and benign; thus, close follow-up of the patients with endoscopy could be considered sufficient as a therapeutic management.
  • Three cases of granular cell tumors with complaints of epigastric discomfort, regurgitation, nausea, and vomiting, which were detected in the lower part of the esophagus on upper gastrointestinal tract endoscopy, are discussed with the most recent literature review on this subject.
  • [MeSH-major] Esophageal Neoplasms / diagnosis. Granular Cell Tumor / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Esophagoscopy. Female. Humans. Male

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  • (PMID = 19115155.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 53
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7. Dudrap E, Lemierre G, Auquit-Auckbur I, Courville P, Milliez PY: [Abrikossoff's tumor: about one case of inter-mammary cutaneous localization and review of literature]. Ann Chir Plast Esthet; 2008 Dec;53(6):521-5
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  • [Title] [Abrikossoff's tumor: about one case of inter-mammary cutaneous localization and review of literature].
  • [Transliterated title] Tumeur d'Abrikossoff : à propos d'une localisation cutanée du sillon intermammaire et revue de la littérature.
  • SUBJECT: Our report concerns a large inter-mammary cutaneous Abrikossoff tumor on a 41-year-old female patient, which has prompted us to review the literature.
  • CASE: It was a low pre-sternal skin tumor; CT-Scanning showed a homogeneous mass 5 cm high, 4 cm wide and 4 cm deep.
  • DISCUSSION: Abrikossoff tumors (or granular cell tumors) are rare ubiquity tumors locating preferably in ENT and oral cavity mucosa.
  • They are overwhelmingly single and benign but on occasion multifocal or malignant.
  • The use of flaps is not advised as it may delay local recidivation diagnosis.
  • CONCLUSION: Abrikossoff tumors require complete exeresis and mandatory histological examination into possible signs of malignity.
  • [MeSH-major] Granular Cell Tumor / surgery. Skin Neoplasms / surgery

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  • (PMID = 18541358.001).
  • [ISSN] 1768-319X
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 14
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8. De Rezende L, Lucendo AJ, Álvarez-Argüelles H: Granular cell tumors of the esophagus: report of five cases and review of diagnostic and therapeutic techniques. Dis Esophagus; 2007 Oct 01;20(5):436-443

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumors of the esophagus: report of five cases and review of diagnostic and therapeutic techniques.

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  • (PMID = 28203918.001).
  • [ISSN] 1442-2050
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Behzatoğlu K, Bahadir B: Malignant granular cell tumor with unusual histological features. Pathol Int; 2007 Feb;57(2):115-9
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  • [Title] Malignant granular cell tumor with unusual histological features.
  • Malignant granular cell tumor, although uncommon, should be differentiated from a number of granular cell-containing tumors.
  • Reported herein is a distinctive variant of malignant granular cell tumor, clinically presenting as a rapidly enlarging scrotal mass, in which some areas morphologically displayed features indistinguishable from Kaposi sarcoma.
  • Cells in areas simulating Kaposi sarcoma were immunohistochemically the same as typical granular cells in other portions of the tumor.
  • The recognition of this pattern is important because it may predominate and overshadow the original nature of tumor.
  • [MeSH-major] Granular Cell Tumor / pathology. Scrotum / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Sarcoma, Kaposi / diagnosis. Sarcoma, Kaposi / pathology

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  • (PMID = 17300677.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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10. Papachristou DJ, Palekar A, Surti U, Cieply K, McGough RL, Rao UN: Malignant granular cell tumor of the ulnar nerve with novel cytogenetic and molecular genetic findings. Cancer Genet Cytogenet; 2009 May;191(1):46-50
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  • [Title] Malignant granular cell tumor of the ulnar nerve with novel cytogenetic and molecular genetic findings.
  • We report an unusual case of ulnar nerve-based malignant granular cell tumor characterized by gains of chromosome 10 and loss of P16 detected by conventional karyotyping and by fluorescence in situ hybridization, respectively, in a 74-year-old male.
  • To our knowledge, these findings have never been reported previously in malignant granular cell tumors.
  • [MeSH-major] Cytogenetic Analysis. Granular Cell Tumor / genetics. Granular Cell Tumor / pathology. Ulnar Nerve / pathology

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  • (PMID = 19389509.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 57285-09-3 / Inhibins; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
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11. Nasser H, Danforth RD Jr, Sunbuli M, Dimitrijevic O: Malignant granular cell tumor: case report with a novel karyotype and review of the literature. Ann Diagn Pathol; 2010 Aug;14(4):273-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant granular cell tumor: case report with a novel karyotype and review of the literature.
  • Malignant granular cell tumor is a rare neoplasm reported to occur at various sites in the body.
  • Histogenesis of these tumors is still vaguely understood; however, their metastatic potential and adverse prognosis is well-described in the literature.
  • To our knowledge, no specific karyotype characterizes these tumors.
  • Hence, the importance of detecting characteristic cytogenetic alterations in these tumors which might serve, in the future, as a possible aid in diagnosis or therapy.
  • We report a new case of malignant granular cell tumor of the thigh with metastases to abdominal wall and both lungs causing severe dyspnea.
  • Cytogenetic analysis demonstrated that 60% of cultured tumor cells display the following karyotype 46,XX,+X,dic(5;15).
  • [MeSH-major] Granular Cell Tumor / genetics. Granular Cell Tumor / pathology. Soft Tissue Neoplasms / genetics. Soft Tissue Neoplasms / pathology

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20637434.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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12. Canacci AM, Nunez C, Getty P, Abdul-Karim F: Diagnosis of malignant granular cell tumor metastatic to bone by fine needle aspiration cytology: a case report. Acta Cytol; 2010 Mar-Apr;54(2):190-2
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  • [Title] Diagnosis of malignant granular cell tumor metastatic to bone by fine needle aspiration cytology: a case report.
  • BACKGROUND: Malignant granular cell tumor (GCT) is a rare sarcoma that is often difficult to differentiate histologically from its benign counterpart.
  • The patient subse quently underwent curettage of the tumor with prophylactic fixation of the left proximal humerus.
  • CONCLUSION: The diagnosis of metastatic malignant GCT was rendered in this case.
  • The diagnosis necessitates clinical correlation and an understanding of the spectrum of histopathologic changes in GCT and malignant
  • [MeSH-major] Bone Neoplasms / diagnosis. Granular Cell Tumor / diagnosis. Humerus / pathology

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  • (PMID = 20391977.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Gualis J, Carrascal Y, de la Fuente L, Echevarría JR: Heart transplantation treatment for a malignant cardiac granular cell tumor: 33 months of survival. Interact Cardiovasc Thorac Surg; 2007 Oct;6(5):679-81
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  • [Title] Heart transplantation treatment for a malignant cardiac granular cell tumor: 33 months of survival.
  • A malignant granular cell tumor is a high-grade sarcoma with a high rate of metastasis, local recurrence and short survival.
  • We describe a patient who underwent orthotopic heart transplantation due to a metastatic unresectable malignant granular cell tumor.
  • [MeSH-major] Granular Cell Tumor / surgery. Heart Neoplasms / surgery. Heart Transplantation
  • [MeSH-minor] Disease-Free Survival. Female. Humans. Middle Aged. Time Factors. Treatment Outcome

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  • (PMID = 17670739.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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14. Bonfils P, de Preobrajenski N, Elouaret Y, Badoual C, Halimi P, Bigorgne C: [Granular cell tumours (Abrikossoff's tumour) of the parotid region]. Rev Laryngol Otol Rhinol (Bord); 2006;127(3):183-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumours (Abrikossoff's tumour) of the parotid region].
  • [Transliterated title] Tumeur à cellules granuleuses (tumeur d'Abrikossoff) de la loge parotidienne.
  • BACKGROUND: Granular cell tumour (Abrikossoff's tumour) was first described by Abrikossoff in 1926.
  • These tumours are rare and usually presents as a solitary lesion, located mainly in the subcutaneous tissue of the head and neck, and in the oral cavity (tongue).
  • CASE REPORT: We report a rare case of a granular cell tumor of the parotid gland, in a 55-year old woman, who was referred with a left preauricular mass that had rapidly increased in size over 2 months.
  • CONCLUSION: We discuss the classification, pathophysiology and the treatment of granular cell tumours through a review of the literature.
  • [MeSH-major] Granular Cell Tumor / pathology. Granular Cell Tumor / physiopathology. Parotid Neoplasms / pathology. Parotid Neoplasms / physiopathology

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  • (PMID = 17007194.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 13
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15. Pino Rivero V, Marcos García M, Rejas Ugena E, Trinidad Ruiz G, Pardo Romero G, González Palomino A, Gómez de Tejada Romero R, Blasco Huelva A: [Granular cell tumor of the tongue (Abrikossoff's tumor). Report of a case and review of the literature]. An Otorrinolaringol Ibero Am; 2005;32(1):65-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumor of the tongue (Abrikossoff's tumor). Report of a case and review of the literature].
  • [Transliterated title] Tumor de células granulares lingual (tumor de Abrikossoff). Presentación de un caso y revisión de la literatura.
  • Granular cell tumor, myoblastoma or Abrikossoff's tumor is an uncommon benign lesion, usually of slow-growing, that shows a predilection for the oral cavity, especially the tongue.
  • Its real etiopathogenia remains still controversial and in it's histogenesis have been implicated several cell types.
  • We report the case of a 18 years old woman with that diagnosis, confirmed in AP, who was operated by removal of the tumoration that was located in the left half-tongue.
  • [MeSH-major] Granular Cell Tumor / pathology. Tongue Neoplasms / pathology

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  • (PMID = 15803921.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 10
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16. Eriksen JR, Ibsen PH, Gyrtrup HJ: [Granular cell tumor of the colon--Abrikossoff's tumor]. Ugeskr Laeger; 2006 May 22;168(21):2080-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumor of the colon--Abrikossoff's tumor].
  • [Transliterated title] Granularcelletumor i colon--Abrikossoffs tumor.
  • Histopathologic examination of the specimen showed a tubulovillous adenoma with moderate dysplasia and an adjacent 1 x 1 cm submucosal tumor classified as a benign GCT due to the appearance in the light microscope and immunohistochemical analysis.
  • [MeSH-major] Adenoma / pathology. Colonic Neoplasms / pathology. Granular Cell Tumor / pathology

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  • (PMID = 16768929.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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17. Chelly I, Bellil K, Mekni A, Bellil S, Belhadjsalah M, Kchir N, Haouet S, Zitouna MM: Malignant granular cell tumor of the abdominal wall. Pathologica; 2005 Jun;97(3):130-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant granular cell tumor of the abdominal wall.
  • The granular cell tumor is an uncommon tumor that usually appears as a solitary small nodular growth and runs a benign course.
  • The authors report a case of malignant granular cell tumor which was arising in anterior abdominal wall of a 67-year-old woman.
  • Malignant variant is rare and the abdominal wall site is extremely uncommon.
  • [MeSH-major] Abdominal Neoplasms / pathology. Abdominal Wall / pathology. Granular Cell Tumor / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Fatal Outcome. Female. Humans. Neoplasm Invasiveness. Neoplasm Proteins / analysis. Postoperative Complications. Pulmonary Embolism / complications

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  • (PMID = 16259279.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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18. Józefowicz-Korczyńska M, Kozłowski Z, Pietruszewska W, Lukomski M: [Granular-cell myoblastoma of the larynx clinical analysis]. Otolaryngol Pol; 2005;59(6):807-12

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  • [Title] [Granular-cell myoblastoma of the larynx clinical analysis].
  • Clinical date of four cases of granular-cell myoblastoma tumors arising in the larynx and clinical analysis of 11 cases published in Polish literature were reviewed and studied.
  • Granular-cell tumor is a rare, usually benign neoplasm that can occur in various part of the body.
  • The larynx tumor is accounting for 7% to 10% of all reported cases.
  • The tumor was generally presented in patients in their forth and fifth decade.
  • Typically the tumors were painless.
  • Clinically the tumors were considered benign.
  • In one case because the location and size of the tumor subtotal laryngectomy was necessary to conduct.
  • The knowledge about natural history and therapeutic implications of such tumors is essential to choose appropriate therapy and planning surgery.
  • [MeSH-major] Granular Cell Tumor / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 16521442.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 18
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19. Elakkumanan LB, Chhabra A, Bose S, Sharma K: Granular cell myoblastoma of tongue: a rare cause of unanticipated difficult intubation. Middle East J Anaesthesiol; 2010 Feb;20(4):573-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell myoblastoma of tongue: a rare cause of unanticipated difficult intubation.
  • We report a case of granular cell myoblastoma of the tongue, as a cause of an unanticipated impossible intubation.
  • [MeSH-major] Granular Cell Tumor / pathology. Intubation, Intratracheal / methods. Neoplasms, Muscle Tissue / pathology. Tongue Neoplasms / pathology

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  • (PMID = 20394257.001).
  • [ISSN] 0544-0440
  • [Journal-full-title] Middle East journal of anaesthesiology
  • [ISO-abbreviation] Middle East J Anaesthesiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Lebanon
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20. Suzuki S, Maeda S, Sasajima K, Yoshida H, Yokoyama T, Maruyama H, Matsutani T, Liu A, Hosone M, Tanno M, Uchida E: Malignant granular cell tumor in the gluteal region with unusual pathologic features. Int Surg; 2010 Oct-Dec;95(4):360-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant granular cell tumor in the gluteal region with unusual pathologic features.
  • Malignant granular cell tumors (MGCTs) are very rare soft tissue sarcomas.
  • Definite criteria for pathologic diagnosis and the optimal treatment strategy have not been fully established.
  • Here, we describe a 76-year-old woman with a huge MGCT in the right gluteal region, who developed a local recurrence and died from that tumor 14 months after undergoing an operation for the primary tumor.
  • Although microscopic examination revealed that round and granular tumor cells staining for S-100 protein were dominant, components of the spindle cell sarcoma reacting with alpha smooth muscle actin were partially observed.
  • MGCT is believed to originate from Schwann cells; however, pathologic findings in our case showed both Schwannian and non-Schwannian features.
  • [MeSH-major] Buttocks / pathology. Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Soft Tissue Neoplasms / pathology. Soft Tissue Neoplasms / surgery

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  • (PMID = 21309422.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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21. Basu D, Sengupta A, Adhikari D, Dam A, Anwar T: Granular cell myoblastoma of the tongue in a 2-year-old girl: a case report. J Indian Med Assoc; 2010 Mar;108(3):170, 175
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell myoblastoma of the tongue in a 2-year-old girl: a case report.
  • Granular cell tumours are uncommon lesions, although the head and neck region accounts for approximately 50% of all lesions.
  • It is not clear whether or not granular cell tumour is a true neoplasm, a developmental anomaly, or a trauma-induced proliferation.
  • The basic cell of origin is now thought to be neural, although past reports frequently indicated an origin from striated muscle, or less frequently an origin from histiocytes, fibroblasts or pericytes.
  • The tumour generally occurs in middle or older aged adults.
  • More than a third of all granular cell tumours occur on the lingual dorsum, usually as a sessile, painless, somewhat firm, immoveable nodule less than 1.5 cm in greatest diameter.
  • Histochemical and ultrastructural studies propose the origin of the lesion from Schwann cells, striated muscle, mesenchymal cells, histiocytes and epithelial cells.
  • As most of the granular cell tumours are benign, surgical excision of the lesion is the treatment of choice.
  • [MeSH-major] Granular Cell Tumor / pathology. Tongue Neoplasms / pathology

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  • (PMID = 21043356.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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22. Gleason BC, Nascimento AF: HMB-45 and Melan-A are useful in the differential diagnosis between granular cell tumor and malignant melanoma. Am J Dermatopathol; 2007 Feb;29(1):22-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] HMB-45 and Melan-A are useful in the differential diagnosis between granular cell tumor and malignant melanoma.
  • Granular cell tumors (GCTs), especially if atypical or malignant, may share cytomorphologic and architectural features with malignant melanoma, when the latter shows granular cell change.
  • By immunohistochemistry, both tumors are strongly positive for S-100 protein and frequently express other nonspecific markers such as CD68, NSE, and NKIC3.
  • In the current study, we reviewed 60 cases of conventional cutaneous, mucosal, and visceral GCT and studied the use of immunoperoxidase staining for the differential diagnosis between malignant melanoma and GCT.
  • All of the tumors were positive for S-100 protein.
  • Fifty-seven (95%) tumors were negative for Melan-A, one case was focally positive, and two cases showed rare positive tumor cells.
  • None of the tumors expressed HMB-45.
  • In conclusion, GCT and malignant melanoma can be reliably differentiated on the basis of immunohistochemical stains in the majority of cases.
  • Although not always positive in malignant melanoma, in this context, HMB-45 expression seems to be 100% specific for the diagnosis of melanoma.
  • The latter finding highlights the limited specificity of this antibody in the diagnosis of melanocytic tumors.
  • [MeSH-major] Antigens, Neoplasm / metabolism. Granular Cell Tumor / diagnosis. Melanoma / diagnosis. Neoplasm Proteins / metabolism. Skin Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans. MART-1 Antigen. Melanoma-Specific Antigens. Microphthalmia-Associated Transcription Factor / metabolism. Retrospective Studies. S100 Proteins / metabolism. Sensitivity and Specificity

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  • (PMID = 17284958.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Microphthalmia-Associated Transcription Factor; 0 / Neoplasm Proteins; 0 / S100 Proteins
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23. Gomard-Mennesson E, Isaac S, Freymond N, Guibert B, Pacheco Y, Devouassoux G: [Pulmonary metastases from Abrikossoff's tumour. Transformation capability of a benign granular cell tumour]. Rev Mal Respir; 2007 Sep;24(7):900-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pulmonary metastases from Abrikossoff's tumour. Transformation capability of a benign granular cell tumour].
  • [Transliterated title] Métastases pulmonaires d'une tumeur d'Abrikossoff. Transformation ou potentiel évolutif d'une tumeur bénigne à cellules granuleuses.
  • INTRODUCTION: Abrikossoff's tumour or granular cell tumour is usually benign involving multiple anatomical sites, most frequently the head, neck and airways.
  • Occasional observations of aggressive malignant tumours have been reported, associated with a poor prognosis.
  • CASE REPORT: We report the case of a mammary Abrikossoff's tumour, initially considered benign and treated solely by local surgery.
  • Seven years later the tumour was responsible for the development of sub-cutaneous and pulmonary metastases.
  • CONCLUSION: This original observation reports the case of a benign granular cell tumour that underwent malignant transformation after an interval of 7 years as indicated by the clinical progress and the cellular proliferation index Ki-67.
  • [MeSH-major] Breast Neoplasms / pathology. Cell Transformation, Neoplastic / pathology. Granular Cell Tumor / secondary. Lung Neoplasms / secondary
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Follow-Up Studies. Humans. Ki-67 Antigen / analysis. S100 Proteins / analysis. Skin Neoplasms / secondary

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  • (PMID = 17925675.001).
  • [ISSN] 0761-8425
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / S100 Proteins
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24. Mahoney A, Garg A, Wolpowitz D, Mahalingam M: Atypical granular cell tumor-apropos of a case with indeterminate malignant potential. Am J Dermatopathol; 2010 Jun;32(4):370-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical granular cell tumor-apropos of a case with indeterminate malignant potential.
  • Malignant granular cell tumor is relatively uncommon, constituting 1%-2% of all granular cell tumors.We describe a case of a 53-year-old woman who presented with a 4.5 X 5.5-cm nodule on her left lower abdomen.
  • An initial punch biopsy revealed a pandermal infiltrate of epithelioid cells with finely granular cytoplasm and vesicular nuclei-histologic features consistent with a granular cell tumor.
  • Given the large size of the neoplasm, an excisional biopsy was recommended that revealed in addition to the above, focal ulceration, epithelioid cells with vesicular nuclei and prominent nucleoli, increased mitotic activity, pleomorphism, and epidermotropism with pagetoid spread-features that were histologically concerning for malignant transformation.
  • [MeSH-major] Granular Cell Tumor / pathology. Skin Neoplasms / pathology

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  • (PMID = 20514678.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Spinzi G, Fante MD, Masci E, Buffoli F, Colombo E, Fiori G, Ravelli P, Ceretti E, Minoli G, SIED Lombardia Working Group, Italy: Lack of colonic neoplastic lesions in patients under 50 yr of age with hematochezia: a multicenter prospective study. Am J Gastroenterol; 2007 Sep;102(9):2011-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Malignant polyps were found in two patients (0.6%), aged 30-40 yr, one in the rectum and one in the sigmoid.
  • A malignant polyp of the cecum was found in a 41-yr-old patient.
  • Another, aged 47, had a malignant granular-cell tumor of the rectum.
  • [MeSH-major] Colonic Neoplasms / diagnosis. Gastrointestinal Hemorrhage / etiology. Rectal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Colonoscopy. Female. Humans. Intestinal Diseases / complications. Intestinal Diseases / diagnosis. Male. Middle Aged. Sigmoid Neoplasms / complications. Sigmoid Neoplasms / diagnosis

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  • (PMID = 17521401.001).
  • [ISSN] 0002-9270
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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26. Rudisaile SN, Hurt MA, Santa Cruz DJ: Granular cell atypical fibroxanthoma. J Cutan Pathol; 2005 Apr;32(4):314-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell atypical fibroxanthoma.
  • We report on two patients with granular cell atypical fibroxanthoma.
  • Microscopically, these neoplasms showed a dermal proliferation of pleomorphic granular cells with irregular hyperchromatic nuclei, multinucleated cells, and scattered mitoses.
  • The differential diagnosis of granular cells in neoplasms containing cytological pleomorphism is challenging in view of the many different neoplasms that may present with granular cytoplasm.
  • These include the conventional granular cell tumor and its malignant form, leiomyoma, leiomyosarcoma, dermatofibroma, dermatofibrosarcoma protuberans, and angiosarcoma.
  • [MeSH-major] Granular Cell Tumor / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Biomarkers, Tumor. Humans. Immunohistochemistry. Male. Mohs Surgery. Treatment Outcome

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  • (PMID = 15769283.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 25
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27. Mnasri H, Bouchoucha S: Granular cell tumour of the perianal region: which therapeutic attitude? Acta Chir Belg; 2005 Feb;105(1):112-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumour of the perianal region: which therapeutic attitude?
  • Granular cell tumours are uncommon soft tissue tumours that could be located anywhere throughout the body.
  • Most of time they are benign but the diagnosis of malignancy is difficult to establish on histology: this is why the therapeutic decision is not easy to take in particular for some locations.
  • We report the case of a 18-year old man: he presented, in the perianal region, a granular cell tumour of uncertain malignant potential (so far the first case described in the literature) for which we decided a conservative surgical treatment that failed.
  • [MeSH-major] Anus Neoplasms / surgery. Granular Cell Tumor / surgery

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  • (PMID = 15790218.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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28. Betlach J, Kohout A, Spacek J: [Primitive nonneural granular cell tumor of skin (case report)]. Cesk Patol; 2006 Oct;42(4):191-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primitive nonneural granular cell tumor of skin (case report)].
  • Primitive nonneural granular cell tumor was recognized in an 82-year-old man, mimicking a granuloma in the scalp.
  • Despite its disturbing cytomorphology, this histogenetically enigmatic tumor with unusual immunoprophile (NK1-C3, CD 68 and NSE positivity; S-100 protein negativity) behaves indolently.
  • [MeSH-major] Granular Cell Tumor / pathology. Scalp. Skin Neoplasms / pathology

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  • (PMID = 17171975.001).
  • [ISSN] 1210-7875
  • [Journal-full-title] Československá patologie
  • [ISO-abbreviation] Cesk Patol
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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29. Colella R, Sidoni A, Bellezza G, Cavaliere A: A unique simultaneous occurrence of paratracheal granular cell tumor and papillary thyroid carcinoma. Int J Surg Pathol; 2007 Jan;15(1):82-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A unique simultaneous occurrence of paratracheal granular cell tumor and papillary thyroid carcinoma.
  • We report an unusual case of granular cell tumor in the paratracheal region detected during total thyroidectomy for papillary carcinoma and clinically misdiagnosed as tracheal infiltration of thyroid neoplasia.
  • Histologically, the granular cell tumor had infiltrated the thyroid gland close behind the papillary carcinoma.
  • At immunohistochemical investigation, the cells showed diffuse positivity for S-100, neuron-specific enolase, and CD68, and surprisingly, positivity also for galectin-3 and HBME-1.
  • A granular cell tumor should also be considered in the cytologic differential diagnosis of the thyroid and paratracheal nodules.
  • [MeSH-major] Carcinoma, Papillary / pathology. Granular Cell Tumor / pathology. Neoplasms, Multiple Primary / pathology. Thyroid Neoplasms / pathology. Tracheal Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Metastasis / pathology

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  • (PMID = 17172506.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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30. Yilmaz AD, Unlu RE, Orbay H, Sensoz O: Recurrent granular cell tumor: how to treat. J Craniofac Surg; 2007 Sep;18(5):1187-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent granular cell tumor: how to treat.
  • Granular cell tumor is an uncommon lesion usually located in the head and neck region (50%) with a female sex predominance.
  • Granular cell tumor has a peculiar clinical behavior ranging from clearly benign, locally aggressive, or manifestly malignant.
  • In this article, we present a case of recurrent benign granular cell tumor with the discussion of the treatment modalities.
  • The mass was excised two times at different centers and diagnosed as granular cell tumor after the pathologic examination.
  • [MeSH-major] Granular Cell Tumor / pathology. Head and Neck Neoplasms / pathology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 17912112.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. White JB, Glade R, Rossi CT, Bielamowicz S: Granular cell tumors of the larynx: diagnosis and management. J Voice; 2009 Jul;23(4):516-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumors of the larynx: diagnosis and management.
  • In this case study, a retrospective review of chart and literature was done to discuss the presentation and treatment of granular cell tumors of the larynx.
  • One patient was diagnosed and treated successfully with surgical resection of a laryngeal granular cell tumor.
  • Granular cell tumors should be considered in the differential diagnosis of laryngeal masses, particularly in the posterior glottis.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Granular Cell Tumor / therapy. Laryngeal Neoplasms / diagnosis. Laryngeal Neoplasms / therapy
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Larynx / pathology. Larynx / surgery. Recovery of Function. Treatment Outcome. Voice

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  • (PMID = 18346870.001).
  • [ISSN] 1873-4588
  • [Journal-full-title] Journal of voice : official journal of the Voice Foundation
  • [ISO-abbreviation] J Voice
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 9
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32. El Aouni N, Laurent I, Terrier P, Mansouri D, Suciu V, Delaloge S, Vielh P: Granular cell tumor of the breast. Diagn Cytopathol; 2007 Nov;35(11):725-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the breast.
  • We report a case of a 43-yr-old woman with a granular cell tumor of the breast.
  • The tumor was dense with ill-defined borders at mammography and hypoechoic, hypovascular, and poorly limited at ultrasonography.
  • Cytologic examination revealed the presence of highly cellular material, composed of both large cohesive groups and single cells often admixed with connective tissue.
  • These cells had ill-defined abundant granular cytoplasm and bland regular small nuclei.
  • The cytological diagnosis of granular cell tumor of the breast was confirmed by histological examination of the surgical specimen following a breast lumpectomy.
  • [MeSH-major] Breast Neoplasms / pathology. Granular Cell Tumor / pathology

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17924412.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Poyraz CE, Kiratli H, Söylemezoğlu F: Granular cell tumor of the inferior rectus muscle. Korean J Ophthalmol; 2009 Mar;23(1):43-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the inferior rectus muscle.
  • Excisional biopsy of the mass revealed granular cell tumor composed of S-100 positive cells with acidophilic granular cytoplasm and a peripheral lymphocytic infiltration.
  • Granular cell tumor, which is very rare in the orbit, should be considered in the differential diagnosis of tumors adjacent to or within the extraocular muscles, particularly in the inferior orbit.
  • [MeSH-major] Eye Neoplasms / pathology. Granular Cell Tumor / pathology. Muscle Neoplasms / pathology. Oculomotor Muscles / pathology
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Middle Aged

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  • [Cites] Plast Reconstr Surg. 1969 Mar;43(3):315-7 [4305121.001]
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  • (PMID = 19337479.001).
  • [ISSN] 2092-9382
  • [Journal-full-title] Korean journal of ophthalmology : KJO
  • [ISO-abbreviation] Korean J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2655740
  • [Keywords] NOTNLM ; Extraocular muscle / Granular cell tumor / Inferior rectus / Magnetic resonance imaging / Orbit
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34. Patel A, Lefemine V, Yousuf SM, Abou-Samra W: Granular cell tumour of the pectoral muscle mimicking breast cancer. Cases J; 2008;1(1):142

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumour of the pectoral muscle mimicking breast cancer.
  • Histological examination revealed this to be a benign granular cell tumour.Granular cell tumour is a rare tumour that very occasionally presents within the breast.
  • It is possibly of Schwann cell origin.
  • Tumour cells showing positive immunostaining for S-100 and PAS is in keeping with the diagnosis.

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  • [Cites] Br J Radiol. 2007 Dec;80(960):970-4 [17940129.001]
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  • (PMID = 18775077.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2538504
  •  go-up   go-down


35. Rego A, Amado J, Esteves I, Almeida J, Furtado A, Couceiro A, Moura e Sá J: [Endobronchial granular cell tumor - what approach to take]. Rev Port Pneumol; 2006 Jul-Aug;12(4):463-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endobronchial granular cell tumor - what approach to take].
  • [Transliterated title] Tumor de células granulares endobrônquico - Como abordamos?
  • Granular cell tumor is a mesenchymal neoplasm almost always benign, with tendency to recurrence.
  • The authors describe two cases of endobronchial granular cell tumours, discuss the particularities of this pathology as well as the treatment options, with particular attention to the use of endobronchial excision and criotherapy.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Bronchial Neoplasms / therapy. Granular Cell Tumor / diagnosis. Granular Cell Tumor / therapy

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  • (PMID = 16969575.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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36. Ahdoot M, Rodgers IR: Granular cell tumor of the orbit: magnetic resonance imaging characteristics. Ophthal Plast Reconstr Surg; 2005 Sep;21(5):395-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the orbit: magnetic resonance imaging characteristics.
  • The tumor proved to be a granular cell tumor.
  • Granular cell tumors are rare neoplasms that may affect the orbit, lacrimal apparatus, conjunctiva, and caruncle.
  • This is the first report describing the MRI characteristics of orbital granular cell tumors.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Orbit / pathology. Orbital Neoplasms / diagnosis

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  • (PMID = 16234712.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Lee EJ, Choo HJ, Kim DW, Yoon JH, Cha SS, Lee WJ, Yoon HK: A retroperitoneal granular cell tumour that mimics pancreatic cancer. Br J Radiol; 2009 Aug;82(981):e194-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A retroperitoneal granular cell tumour that mimics pancreatic cancer.
  • Granular cell tumour is a rare disorder that is characterised by an oval-shaped tumour that has with eosinophilic granules within the tumour cells.
  • It is extremely rare to find this disease arising from the retroperitoneum.
  • We report here on a case of a 46-year-old man with a retroperitoneal granular cell tumour that mimics pancreatic cancer, and describe the CT and MRI findings.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Pancreatic Neoplasms / diagnosis. Retroperitoneal Neoplasms / diagnosis
  • [MeSH-minor] Contrast Media. Diagnosis, Differential. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Retroperitoneal Space. Tomography, Spiral Computed / methods

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  • (PMID = 19729550.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media
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38. Marangi GF, Toto V, Poccia I, Gigliofiorito P, Brunetti B, Persichetti P: Multiple localization of granular cell tumour: a case report. Cases J; 2009;2:8751

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple localization of granular cell tumour: a case report.
  • INTRODUCTION: Granular cell tumour, also known as Abrikossoff's tumour, is a rare entity occurring in the skin as well as in internal organs, more common among the third to fifth decade of life.
  • It has often been described as a peripheral neuroectodermal tumour and its clinical behaviour is usually benign although malignant and multifocal forms are also known to occur.
  • CASE PRESENTATION: We report a case of multiple granular cell tumour in a 17-year-old Caucasian woman who presented with a nodular lesion in the popliteal cave, diagnosed as an Abrikossoff's Tumour, followed 2 years later by another soft tissue mass in the neck.
  • CONCLUSION: This case is quite rare: only a few cases were presented in literature with an extended period of time before the clinical presentation of subsequent disease.

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  • [Cites] Hum Pathol. 1994 Nov;25(11):1172-8 [7959661.001]
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  • (PMID = 20184692.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2827134
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39. Newman E, Eichenfield LF: Granular cell tumor on the palm of an 8-year-old girl. Pediatr Dermatol; 2010 Nov-Dec;27(6):656-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor on the palm of an 8-year-old girl.
  • Granular cell tumors are rare benign peripheral nerve neoplasms that are most commonly reported on the tongue and oral mucosa.
  • We report a child with a granular cell tumor of the palm that required removal by an orthopedic hand surgeon.
  • [MeSH-major] Granular Cell Tumor / pathology. Hand. Peripheral Nervous System Neoplasms / pathology

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  • [Copyright] © 2010 Wiley Periodicals, Inc.
  • (PMID = 21510018.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Bekteshi E, Toth JW, Benninghoff MG, Kang J, Betancourt M: Granular cell tumor of trachea. J Bronchology Interv Pulmonol; 2009 Jan;16(1):68-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of trachea.
  • Granular cell tumors of the tracheobronchial tree are rare benign lesions of neurogenic origin.
  • These benign tumors mostly involve the skin, oral cavity, or esophagus.
  • There is no consensus regarding treatment of granular cell tumors.

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  • (PMID = 23168477.001).
  • [ISSN] 1944-6586
  • [Journal-full-title] Journal of bronchology & interventional pulmonology
  • [ISO-abbreviation] J Bronchology Interv Pulmonol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. Scaranelo AM, Bukhanov K, Crystal P, Mulligan AM, O'Malley FP: Granular cell tumour of the breast: MRI findings and review of the literature. Br J Radiol; 2007 Dec;80(960):970-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumour of the breast: MRI findings and review of the literature.
  • Granular cell tumours (GCTs) are uncommon, usually benign neoplasms that can mimic malignancy on breast imaging.
  • We report a case of granular cell tumour of the breast presenting as a suspicious lesion on breast imaging, and review the MRI features of GCTs.
  • [MeSH-major] Breast Neoplasms / diagnosis. Granular Cell Tumor / diagnosis

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  • (PMID = 17940129.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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42. Dhingra M, Pantola C, Agarwal A: Congenital granular cell tumor of the alveolar ridge. Indian J Pathol Microbiol; 2010 Apr-Jun;53(2):327-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital granular cell tumor of the alveolar ridge.
  • Congenital epulis or neonatal granular cell tumor is a tumor whose histogenesis has long been debated.
  • It is dissimilar to other granular cell tumors; the latter having derivation from Schwann cells and hence being S-100 positive.
  • We report a case of congenital granular cell tumor in a newborn female child that was uneventfully operated.
  • [MeSH-major] Alveolar Process / pathology. Gingival Neoplasms / diagnosis. Gingival Neoplasms / pathology. Granular Cell Tumor / diagnosis. Granular Cell Tumor / pathology

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  • (PMID = 20551547.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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43. Sailors JL, French SW: The unique simultaneous occurrence of granular cell tumor, gastrointestinal stromal tumor, and gastric adenocarcinoma. Arch Pathol Lab Med; 2005 May;129(5):e121-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The unique simultaneous occurrence of granular cell tumor, gastrointestinal stromal tumor, and gastric adenocarcinoma.
  • Granular cell tumors are generally benign oncocytoid lesions of schwannian origin that are often incidental findings in many locations.
  • Gastrointestinal stromal tumors occur in older adults and express the c-Kit protein (CD117).
  • Both of these tumors have been described in association with many other entities; however, they have never been reported to occur jointly.
  • This report is prompted by the simultaneous appearance of 2 granular cell tumors, a gastrointestinal stromal tumor, and a gastric adenocarcinoma in a 65-year-old woman with a history of breast carcinoma and granular cell tumor.
  • To our knowledge, this is the first case report of these tumors occurring simultaneously.
  • [MeSH-major] Adenocarcinoma / pathology. Gastrointestinal Neoplasms / pathology. Granular Cell Tumor / pathology. Neoplasms, Multiple Primary / pathology. Stomach Neoplasms / pathology. Stromal Cells / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Female. Humans. Immunohistochemistry

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  • (PMID = 15859656.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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44. Kondo T, Kajimoto S, Okuda H, Toma H, Tanabe K: A case of granular cell tumor of the bladder successfully managed with extraperitoneal laparoscopic surgery. Int J Urol; 2006 Jun;13(6):827-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of granular cell tumor of the bladder successfully managed with extraperitoneal laparoscopic surgery.
  • Granular cell tumor is a benign neoplasm which frequently occurs in the oral cavity, skin, and subcutaneous tissue.
  • Granular cell tumor of the bladder is an extremely rare disease, and only nine cases have been reported.
  • We present here an additional case of granular cell tumor occurring in the bladder.
  • Unlike the other tumors reported, this tumor extruded into the Retzius' cavity.
  • Therefore, the tumor was successfully excised through extraperitoneal laparoscopic surgery.
  • The small tumor located in Retzius' cavity could be managed with extraperitoneal laparoscopic surgery.
  • [MeSH-major] Granular Cell Tumor / therapy. Laparoscopy. Urinary Bladder Neoplasms / therapy

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  • (PMID = 16834673.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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45. Hülagü S, Sentürk O, Aygün C, Gürbüz Y, Kocaman O, Celebi A, Konduk T: Granular cell tumor of esophagus removed with endoscopic submucosal dissection. Turk J Gastroenterol; 2007 Sep;18(3):188-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of esophagus removed with endoscopic submucosal dissection.
  • Granular cell tumors of the esophagus are rare neoplasms and their diagnosis is mainly based on histopathologic examination of endoscopic biopsies.
  • In this case report, we describe a granular cell tumor of the esophagus in an adult patient and briefly discuss the literature concerning clinicopathologic aspects and management of these uncommon tumors.
  • In this patient, we describe the removal of the tumor by endoscopic submucosal dissection technique.
  • [MeSH-major] Dissection / methods. Endoscopy, Gastrointestinal / methods. Esophageal Neoplasms / surgery. Granular Cell Tumor / surgery. Mucous Membrane / surgery

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  • [CommentIn] Turk J Gastroenterol. 2007 Sep;18(3):135-8 [17891685.001]
  • (PMID = 17891693.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Viscosupplements; 9004-61-9 / Hyaluronic Acid
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46. Golio DI, Prabhu S, Hauck EF, Esmaeli B: Surgical resection of locally advanced granular cell tumor of the orbit. J Craniofac Surg; 2006 May;17(3):594-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical resection of locally advanced granular cell tumor of the orbit.
  • We report a case of locally advanced granular cell tumor of the orbit treated by a multidisciplinary surgical approach.
  • A 49-year-old woman with a recently biopsied granular cell tumor of the orbit was referred to our tertiary care cancer center for evaluation of a right-sided globe ptosis and a palpable mass in the right orbit that had been present for approximately two years.
  • Histologic evaluation of the mass revealed solid nests of polygonal cells that had centrally located, round nuclei with abundant eosinophilic granular cytoplasm.
  • During the most recent follow-up visit six months after surgery, the patient had no clinical evidence of tumor recurrence, had minimal residual ptosis and exposure keratopathy, and had stable visual function.
  • [MeSH-major] Granular Cell Tumor / surgery. Orbital Neoplasms / surgery
  • [MeSH-minor] Biopsy. Cell Nucleus / ultrastructure. Craniotomy. Cytoplasmic Granules / ultrastructure. Exophthalmos / surgery. Female. Frontal Bone / surgery. Humans. Middle Aged. Oculomotor Muscles / surgery. Orbit / surgery. S100 Proteins / analysis. Tomography, X-Ray Computed. Zygoma / surgery

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  • (PMID = 16770206.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / S100 Proteins
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47. Levavi H, Sabah G, Kaplan B, Tytiun Y, Braslavsky D, Gutman H: Granular cell tumor of the vulva: six new cases. Arch Gynecol Obstet; 2006 Jan;273(4):246-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the vulva: six new cases.
  • Granular cell tumors are rare neoplastic skin and soft tissue lesions: only 1-2% are malignant.
  • We present our experience with granular cell tumors of the vulva in six patients, all of whom had wide local excisions and were followed-up in our outpatient clinic for 3-171 months.
  • None of the others has evidence of the disease.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Foot Diseases / surgery. Humans. Middle Aged. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery. Toes / surgery

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  • (PMID = 16133461.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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48. Lauwers K, Bestman TJ, Bergmans G, Molderez C: Granular cell tumour of the male breast. Acta Chir Belg; 2008 Jan-Feb;108(1):112-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumour of the male breast.
  • Granular cell tumour (GCT) is a rare neoplasm that can be found in multiple sites throughout the body.
  • In general, it appears as a singular benign lesion, although it can be multi-focal and rare cases with malignant behaviour have been reported.
  • We report a rare case of granular cell tumour of the nipple in the male breast, treated by wide local excision.
  • [MeSH-major] Breast Neoplasms, Male / surgery. Granular Cell Tumor / surgery

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  • (PMID = 18411585.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Belgium
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49. Kutuya N, Akiduki A: Radiologic appearance of a bronchial granular cell tumor with secondary obstructive changes. Clin Imaging; 2010 Mar-Apr;34(2):148-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiologic appearance of a bronchial granular cell tumor with secondary obstructive changes.
  • Bronchial granular cell tumor is a rare neoplasm.
  • This report describes a 16-year-old female with this tumor in the right upper lobe.
  • The tumor completely occluded the bronchial lumen and thus caused obstructive changes of the lung distal to the tumor.
  • [MeSH-major] Bronchial Diseases / etiology. Bronchial Diseases / radiography. Bronchial Neoplasms / complications. Bronchial Neoplasms / radiography. Granular Cell Tumor / complications. Granular Cell Tumor / radiography

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20189081.001).
  • [ISSN] 1873-4499
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Ihara K, Ito H, Nakajima Y, Fukaya E, Nakazawa H, Nozaki M: Granular cell tumor of the suprasternal space. J Dermatol; 2010 Oct;37(10):900-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the suprasternal space.
  • A case of granular cell tumor (GCT) was reported.
  • The tumor was excised with several millimeters margin of normal tissue above the deep cervical fascia and the wound was closed primarily.
  • Histological examination on hematoxylin-eosin stain showed a tumor growth in the mid- to deep dermis and eosinophilic small granules that were consistent with granular cell tumors.
  • We experienced a case of a granular cell tumor occurring in the suprasternal space and report the importance of including it in the differential diagnosis of subcutaneous soft tissue tumors.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Skin Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • [Copyright] © 2010 Japanese Dermatological Association.
  • (PMID = 20860741.001).
  • [ISSN] 1346-8138
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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51. Caltabiano R, Cappellani A, Di Vita M, Lanzafame S: The unique simultaneous occurrence of a squamous cell carcinoma and a granular cell tumor of the tongue at the same site: a histological and immunohistochemical study. J Craniofac Surg; 2008 Nov;19(6):1691-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The unique simultaneous occurrence of a squamous cell carcinoma and a granular cell tumor of the tongue at the same site: a histological and immunohistochemical study.
  • We report a case of a 47-year-old man with a granular cell tumor (GCT) of the tongue colocalized with a squamous cell carcinoma.
  • Furthermore, we performed an immunohistochemical analysis with p63 to distinguish pseudoepitheliomatous hyperplasia from invasive squamous cell carcinoma.
  • Clinicians and pathologists must be made aware of this potential diagnostic pitfall so that the workup of a tongue lesion does not end prematurely with a benign diagnosis of granular cell tumor with overlying pseudoepitheliomatous hyperplasia.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Granular Cell Tumor / pathology. Neoplasms, Multiple Primary / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Cell Nucleus / ultrastructure. Cytoplasm / ultrastructure. Epithelium / pathology. Follow-Up Studies. Humans. Hyperplasia. Immunohistochemistry. Male. Membrane Proteins / analysis. Middle Aged. Mouth Mucosa / pathology. Neoplasm Invasiveness. S100 Proteins / analysis

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  • (PMID = 19098584.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CKAP4 protein, human; 0 / Membrane Proteins; 0 / S100 Proteins
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52. Ishibashi H, Ota S, Hirose M, Tanio N, Fukuchi K, Muro H, Nakajima N: [Granular cell tumor in the mediastinum; report of a case]. Kyobu Geka; 2010 Jun;63(6):496-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumor in the mediastinum; report of a case].
  • Granular cell tumor is found in various organs but is rare in the mediastinum.
  • We report a case of 21-year-old woman with a granular cell tumor in the left upper mediastinum.
  • Chest computed tomography (CT) showed a 30 x 20 mm well circumscribed tumor in the left upper mediastinum.
  • Tumor resection was performed.
  • It was found that the tumor involved the sympathetic nerve.
  • Histopathologically, the tumor consisted of cells with eosinophilic granules and diagnosed as a granular cell tumor.
  • [MeSH-major] Granular Cell Tumor / pathology. Mediastinal Neoplasms / pathology

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  • (PMID = 20533744.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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53. Novakov-Mikić A, Ivanović L, Lucić M, Kiralj A, Koprivsek K, Vucković N: [Prenatal diagnosis of granular cell myoblastoma--a case report]. Med Pregl; 2006 Nov-Dec;59(11-12):573-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prenatal diagnosis of granular cell myoblastoma--a case report].
  • INTRODUCTION: The aim of this paper is to present a case of prenatal diagnosis of a congenital tumor of the oral cavity diagnosed at 28 weeks of gestation.
  • CASE REPORT: After the diagnosis of oral cavity tumor was made by 21) ultrasound, a 3D scan was performed, which confirmed the diagnosis revealing a peduncle at the upper border of maxilla.
  • Magnetic resonance imaging was performed, confirming the diagnosis and the site of the tumor.
  • Regular three-week follow-up scans were performed to follow the growth of the tumor, as well as the state of the amniotic fluid.
  • No tumor growth was detected, and the amniotic fluid volume was normal until 39 weeks of gestation.
  • Cesarean section was scheduled, due to the risk of tumor disruption during a vaginal delivery.
  • The histopathological diagnosis was: granular cell myoblastoma.
  • The female newborn was developing normally, and at 5 months of age there were no traces of scarring at the place of the tumor.
  • CONCLUSION: In cases of prenatal diagnosis of tumors of the oral cavity, where development of polyhydramnios can be expected, as well as difficulties with feeding and breathing after birth, it is important to make a plan for adequate follow-up and prompt surgical treatment immediately after birth.
  • [MeSH-major] Granular Cell Tumor / congenital. Mouth Neoplasms / congenital. Mouth Neoplasms / diagnosis
  • [MeSH-minor] Female. Fetal Diseases / diagnosis. Humans. Infant, Newborn. Magnetic Resonance Imaging. Pregnancy. Ultrasonography, Prenatal

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  • (PMID = 17633900.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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54. Thacker MM, Humble SD, Mounasamy V, Temple HT, Scully SP: Case report. Granular cell tumors of extremities: comparison of benign and malignant variants. Clin Orthop Relat Res; 2007 Feb;455:267-73

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case report. Granular cell tumors of extremities: comparison of benign and malignant variants.
  • Granular cell tumors are uncommon soft tissue neoplasms that arise from cells of neural origin.
  • We present three patients with this rare tumor: one with a benign tumor, one with a malignant tumor, and one with a histologically benign tumor that later metastasized to the lung.
  • We studied the difficulty in differentiating between the benign and malignant variants using only histology.
  • [MeSH-major] Granular Cell Tumor / pathology

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  • (PMID = 16936589.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
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55. López-Jornet P: Granular cell tumor of the tongue. N Y State Dent J; 2008 Aug-Sep;74(5):71-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the tongue.
  • Granular cell tumor is an uncommon benign hamartomatous lesion occurring in almost any part of the body.
  • Granular cell lesions may be found in other diverse sites, such as the jaw, skin, gastrointestinal tract and respiratory tract.
  • In this paper, we report the occurrence of an oral granular cell tumor affecting the tongue of a 45-year-old male patient.
  • [MeSH-major] Granular Cell Tumor / pathology. Tongue Neoplasms / pathology

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  • (PMID = 18982973.001).
  • [ISSN] 0028-7571
  • [Journal-full-title] The New York state dental journal
  • [ISO-abbreviation] N Y State Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. Zaidi AH, Ashraf M, Mamoon N, Amin MU: Granular cell tumour of the common bile duct. J Coll Physicians Surg Pak; 2007 Sep;17(9):572-3

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  • [Title] Granular cell tumour of the common bile duct.
  • Granular cell tumors (GCTs) are rare soft tissue neoplasms and occur in different parts of the body.
  • We report a case of granular cell tumour of common bile duct (CBD) in a 39 years old lady, presenting with obstructive jaundice.
  • Complete surgical excision of the tumour was done.

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  • (PMID = 17903412.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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57. Rao D, Rylander H, Drees R, Schwarz T, Steinberg H: Granular cell tumor in a lumbar spinal nerve of a dog. J Vet Diagn Invest; 2010 Jul;22(4):638-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor in a lumbar spinal nerve of a dog.
  • Histopathological evaluation with immunohistochemistry revealed sheets of round to polygonal cells with diffuse granular cytoplasm demonstrating diastase-resistant periodic acid-Schiff reactivity and positive immunoexpression of S100 and neuron-specific enolase.
  • Based on gross, histological, and immunohistochemical evidence, the masses were diagnosed as granular cell tumor.
  • [MeSH-major] Dog Diseases / diagnostic imaging. Granular Cell Tumor / veterinary. Spinal Cord Neoplasms / veterinary. Spinal Nerves / pathology

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  • (PMID = 20622241.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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58. Yoon Y, Curry K: Concurrence of granular cell tumor and Mycobacterium tuberculosis. South Med J; 2005 Oct;98(10):1034-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrence of granular cell tumor and Mycobacterium tuberculosis.
  • Granular cell tumors (GCT) are rare, usually benign neoplasms of Schwann cell origin.
  • This report reviews the literature regarding GCT and presents this unusual case of granular cell tumor co-occurring with active tuberculosis.
  • [MeSH-major] Granular Cell Tumor / complications. Tuberculosis / complications

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  • (PMID = 16295820.001).
  • [ISSN] 0038-4348
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antitubercular Agents; 2KNI5N06TI / Pyrazinamide; 8G167061QZ / Ethambutol; V83O1VOZ8L / Isoniazid; VJT6J7R4TR / Rifampin
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59. Menon G, Easwer HV, Radhakrishnan VV, Nair S: Symptomatic granular cell tumour of the pituitary. Br J Neurosurg; 2008 Feb;22(1):126-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic granular cell tumour of the pituitary.
  • Granular cell tumours (GCT) and pituicytomas are rare tumours seen in the sellar suprasellar region which are believed to arise from either the infundibulum or the posterior lobe of the pituitary gland.
  • We report the case of a 42-year-old male with a granular cell neoplasm of the sellar suprasellar region and attempt to discuss the controversies shrouding this distinct clinicopathological entity.
  • [MeSH-major] Adenoma / diagnosis. Central Nervous System Cysts / diagnosis. Granular Cell Tumor / diagnosis. Pituitary Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Optic Atrophy / etiology. Pituitary Gland / pathology. Recovery of Function / physiology. Treatment Outcome. Visual Acuity / physiology

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  • (PMID = 17952719.001).
  • [ISSN] 0268-8697
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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60. Storck C, Savic S, Egli J, Fischer C, Wolfensberger M: [Granular cell tumor of the larynx: a case report]. HNO; 2008 Dec;56(12):1229-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumor of the larynx: a case report].
  • Granular cell tumors are benign subcutaneous or submucosal lesions of neurogenic origin.
  • However, only about 200 cases of laryngeal granular cell tumors have been reported so far.
  • Most laryngeal granular cell tumors are located in the posterior part of the vocal fold and in the posterior commissure.
  • Differentiation from inflammatory as well as from malignant lesions is possible only by biopsy.
  • However, tumor extension and expected morbidity of the surgery will inevitably influence the extent of the resection.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Laryngeal Neoplasms / diagnosis. Laryngeal Neoplasms / therapy

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  • (PMID = 18340420.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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61. Fitzhugh VA, Maniar KP, Gurudutt VV, Rivera M, Chen H, Wu M: Fine-needle aspiration biopsy of granular cell tumor of the tongue: a technique for the aspiration of oral lesions. Diagn Cytopathol; 2009 Nov;37(11):839-42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration biopsy of granular cell tumor of the tongue: a technique for the aspiration of oral lesions.
  • Granular cell tumor is most commonly located in the tongue.
  • We report a case of FNAB of a granular cell tumor of the tongue in a 29-year-old man with an unusual presenting history and without symptoms.
  • The diagnosis was made based on the cytomorphology of the direct smears and immunohistochemistry on cell block material.
  • We will also describe cytologic features of the neoplasm, differential diagnosis, and our technique for obtaining the material, as we feel this can be repeated by experienced cytopathologists.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Granular Cell Tumor / pathology. Tongue Neoplasms / pathology

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  • (PMID = 19526573.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Mandara MT, Ricci G, Sforna M: A cerebral granular cell tumor in a cat. Vet Pathol; 2006 Sep;43(5):797-800
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A cerebral granular cell tumor in a cat.
  • A cerebral granular cell tumor is described in a 6-year-old, short-haired, female cat.
  • The tumor was observed above the corpus callosum and completely infiltrating the third ventricle.
  • Histologic examination revealed that the tumor was characterized by large cells containing densely packed intracytoplasmic granules and expressed psammoma body-like patterns and cholesterinic degeneration.
  • Immunohistochemical analysis revealed granular neoplastic cells that were diffusely and strongly vimentin-positive, while they did not express cytokeratins, lysozyme, and synaptophysin.
  • Based on morphologic and immunohistochemical findings, the tumor under study was considered to be of meningeal origin arising directly from the meninges or from meningeal elements scattered in the tela choroidea of the third ventricle roof.
  • [MeSH-major] Brain Neoplasms / veterinary. Cat Diseases / pathology. Granular Cell Tumor / veterinary

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  • (PMID = 16966466.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Sidwell RU, Rouse P, Owen RA, Green JS: Granular cell tumor of the scrotum in a child with Noonan syndrome. Pediatr Dermatol; 2008 May-Jun;25(3):341-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the scrotum in a child with Noonan syndrome.
  • Granular cell tumor is a rare neoplasm thought to be of neural origin, composed of cells with distinctive granular cytoplasm.
  • Granular cell tumors most often arise on the tongue, but can occur at any body site, and therefore initial presentation to dermatologists is common.
  • We report a granular cell tumor of the scrotum in a child with Noonan syndrome, known to have a mutation in the PTPN11 gene.
  • No previous reports of granular cell tumor of the scrotum in a child are found.
  • The tumor is usually benign; however, it can have a high local recurrence rate (variable between 2% and 50% dependent on whether initial excision is complete and on the occurrence of an infiltrative growth pattern) and therefore long-term follow-up is necessary.
  • This case highlights the occurrence of granular cell tumor, a diagnosis not to be missed by the dermatologist.
  • In addition, we postulate the possible role of PTPN11 mutations in the development of granular cell tumor.
  • [MeSH-major] Genital Neoplasms, Male / genetics. Granular Cell Tumor / genetics. Mutation. Noonan Syndrome / complications. Protein Tyrosine Phosphatase, Non-Receptor Type 11 / genetics

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  • (PMID = 18577039.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.1.3.48 / PTPN11 protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatase, Non-Receptor Type 11
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64. Stock D, McKee P, Donley B, Lakin R, Goldblum J, Howard M: Granular cell tumor of the toe: a case report. J Foot Ankle Surg; 2009 May-Jun;48(3):358-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the toe: a case report.
  • The authors present a case of a granular cell tumor of the second digit that was treated with a partial digit amputation.
  • Radiographs, magnetic resonance images, and, finally, ultrasound images were used to confirm the presence of an underlying mass, and biopsy confirmed the diagnosis of granular cell tumor.
  • [MeSH-major] Granular Cell Tumor / pathology. Soft Tissue Neoplasms / pathology. Toes / pathology

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  • (PMID = 19423037.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Popovic V, Pekic S, Skender-Gazibara M, Salehi F, Kovacs K: A large sellar granular cell tumor in a 21-year-old woman. Endocr Pathol; 2007;18(2):91-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A large sellar granular cell tumor in a 21-year-old woman.
  • We report here the case of a 21-year-old woman with a large sellar tumor, extending to the suprasellar area associated with growth hormone deficiency, hypogonadism, hypocorticism, and hyperprolactinemia.
  • Transsphenoidal surgery was performed, and histologic, immunohistochemical, and electron microscopic study lead to the diagnosis of granular cell tumor.
  • These tumors are, in most cases, very small and are found incidentally at autopsy of older patients.
  • Our case is exceptional because the tumor developed in a young woman, extended to the suprasellar region, and caused clinical symptoms.
  • [MeSH-major] Granular Cell Tumor / pathology. Pituitary Neoplasms / pathology. Sella Turcica / pathology

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  • (PMID = 17916999.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hormones; 12629-01-5 / Human Growth Hormone
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66. Devi K, Mohanty P, Mohanty L, Bhuyan P, Mishra A, Hazra K: Cytodiagnosis of granular cell tumor: a case report. Indian J Pathol Microbiol; 2007 Jan;50(1):61-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytodiagnosis of granular cell tumor: a case report.
  • Fine needle aspiration diagnosis was benign granular cell tumor which was confirmed by histopathology.
  • Since it is an uncommon tumor, of controversial histogenesis, it is being reported here.
  • [MeSH-major] Granular Cell Tumor / diagnosis

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  • (PMID = 17474262.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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67. Popovska S: [Granular cell tumor of the breast--review of the literature and research for a period of 5 years]. Khirurgiia (Sofiia); 2006;(1):53-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumor of the breast--review of the literature and research for a period of 5 years].
  • Granular cell tumor is relatively rare neoplasm, and always benign in its prognostic behavior.
  • Location of this tumor in the breast presents serious problems for differential diagnosis, both from a clinical point of view and at gross pathologic examination, because of its resemblance to carcinoma.
  • Most granular cell tumors appear to be derived from Schwann cells of peripheral nerves, but many different lesions in the breast show granular cell changes.
  • The authors describe four typical cases of breast granular cell tumors that occurred in patients of different ages, and discuss the most important problems concerning this lesion.
  • [MeSH-major] Breast Neoplasms / pathology. Granular Cell Tumor / pathology

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  • (PMID = 18771140.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Bulgaria
  • [Number-of-references] 11
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68. Irizarry-Rovira AR, Lennox AM, Ramos-Vara JA: Granular cell tumor in the testis of a rabbit: cytologic, histologic, immunohistochemical, and electron microscopic characterization. Vet Pathol; 2008 Jan;45(1):73-7
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  • [Title] Granular cell tumor in the testis of a rabbit: cytologic, histologic, immunohistochemical, and electron microscopic characterization.
  • Pathologic evaluation (exfoliative cytology, histopathology, immunohistochemistry, electron microscopy) indicated that the tumor was an intratesticular granular cell tumor.
  • Granular cell tumor has not been described in rabbits before and has not been described in the testes of animals or postnatal humans.
  • Granular cell tumor should be included as a differential diagnosis of testicular tumors, particularly Leydig cell tumor, because of potential histologic similarities.
  • [MeSH-major] Granular Cell Tumor / veterinary. Rabbits. Testicular Neoplasms / veterinary

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  • (PMID = 18192581.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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69. Irshad A, Pope TL, Ackerman SJ, Panzegrau B: Characterization of sonographic and mammographic features of granular cell tumors of the breast and estimation of their incidence. J Ultrasound Med; 2008 Mar;27(3):467-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization of sonographic and mammographic features of granular cell tumors of the breast and estimation of their incidence.
  • OBJECTIVE: The purpose of this series was to review the spectrum of sonographic and mammographic features of granular cell tumors (GCTs) of the breast and to compare their frequency relative to breast carcinoma.
  • Mammograms were reviewed for tumor size, location, margin characteristics, spiculations, and calcifications.
  • RESULTS: Of 10 GCT cases, 9 tumors occurred in female patients, and 1 occurred in a male patient.
  • All 7 tumors visualized on sonography were hypoechoic masses.
  • Of 8 tumors visualized on mammography, 5 were spiculated, and 3 were well circumscribed.
  • Calcifications were not visualized in any tumor.
  • CONCLUSIONS: Granular cell tumors of the breast are rare neoplasms with a relative frequency of 6.7 per thousand breast carcinomas in our series, which was higher than reported in literature.
  • [MeSH-major] Breast Neoplasms / radiography. Breast Neoplasms / ultrasonography. Granular Cell Tumor / radiography. Granular Cell Tumor / ultrasonography. Mammography. Ultrasonography, Mammary

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  • (PMID = 18314525.001).
  • [ISSN] 0278-4297
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Filipovski V, Banev S, Janevska V, Dukova B: Granular cell tumor of the breast: a case report and review of literature. Cases J; 2009;2:8551

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the breast: a case report and review of literature.
  • Histological evaluation revealed a rare benign neoplasm - granular cell tumor.Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast.
  • The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin.
  • The main histological feature is granular cytoplasm of the tumor cells.From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound.

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  • [Cites] Arch Pathol Lab Med. 1992 Feb;116(2):206-8 [1733419.001]
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  • (PMID = 19918386.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769456
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71. Ramaswamy PV, Storm CA, Filiano JJ, Dinulos JG: Multiple granular cell tumors in a child with Noonan syndrome. Pediatr Dermatol; 2010 Mar-Apr;27(2):209-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple granular cell tumors in a child with Noonan syndrome.
  • Granular cell tumors are benign neurally derived neoplasms, involving cutaneous and subcutaneous tissues; and typically occur as solitary lesions.
  • Multiple granular cell tumors occur in 10% of affected individuals, but are in children.
  • Children with underlying somatic and genetic syndromes, including neurofibromatosis and Noonan syndrome, appear to be at higher risk of developing multiple granular cell tumors.
  • Skin biopsy assists in diagnosis, since granular cell tumors have a similar appearance to other cutaneous nodules.
  • Painful or rapidly growing granular cell tumors should be excised and asymptomatic non-growing granular cell tumors may be observed.
  • Children with multiple granular cell tumors should have a complete physical examination to rule out an underlying genetic syndrome.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Neoplasms, Multiple Primary / diagnosis. Noonan Syndrome / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 20537083.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.1.3.48 / PTPN11 protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatase, Non-Receptor Type 11
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72. Zagólski O, Gajda M, Czajecki K: [Granular cell tumor of the larynx--literature review and case report]. Przegl Lek; 2007;64(9):598-600

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumor of the larynx--literature review and case report].
  • [Transliterated title] Guz ziarnistokomórkowy krtani--przeglad piśmiennictwa i opis przypadku.
  • Granular cell tumor (Abrikosov's tumor) of the larynx is a very uncommon lesion.
  • The exact origin of granular cell tumor is still unclear, however most authors believe it to be a neoplastic process derived from neuroectoderm.
  • The majority of reported tumors were removed by microlaryngoscopy.
  • No tumor was observed.
  • Applying Kleinsasser procedure, a tumor 3 mm in diameter covered with normal mucosa was found growing in the posterior wall of the bottom of the right ventricle.
  • The tumor as well as hypertrophic mucosa of the vocal folds were removed.
  • Histopathological examination of the operative specimen revealed a granular cell tumor and chronic laryngitis.
  • Immunohistochemically tumor cells were positive for S-100.
  • CONCLUSION: Surgical removal of the laryngeal granular cell tumor with indications and extent of the resection like in benign tumors, was therapeutically efficient in the presented case.
  • [MeSH-major] Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Laryngeal Neoplasms / pathology. Laryngeal Neoplasms / surgery

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  • (PMID = 18510083.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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73. Kanno A, Satoh K, Hirota M, Hamada S, Umino J, Itoh H, Masamune A, Egawa S, Motoi F, Unno M, Ishida K, Shimosegawa T: Granular cell tumor of the pancreas: A case report and review of literature. World J Gastrointest Oncol; 2010 Feb 15;2(2):121-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the pancreas: A case report and review of literature.
  • Granular cell tumors, also called Abrikossof's tumors, were originally described by Abrikossof A in 1926.
  • The first case of a pancreatic granular cell tumor was described in 1975 and only 6 cases have been reported.
  • We describe a case of granular cell tumor in the pancreas showing pancreatic duct obstruction.
  • Histological examination showed that the tumor consisted of a nested growth of large tumor cells with ample granular cytoplasm and small round nuclei.
  • The tumor cells expressed S-100 protein and were stained with neuron-specific enolase and periodic acid-Schiff, but were negative for desmin, vimentin, and cytokeratin.
  • The resected tumor was diagnosed as a granular cell tumor.
  • To our knowledge, this is the seventh case of Granular cell tumor of the pancreas to be reported.

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  • (PMID = 21160931.001).
  • [ISSN] 1948-5204
  • [Journal-full-title] World journal of gastrointestinal oncology
  • [ISO-abbreviation] World J Gastrointest Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2999167
  • [Keywords] NOTNLM ; Diagnosis / Distal pancreatectomy / Granular cell tumor / Pancreas
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74. Tamborini F, Cherubino M, Scamoni S, Valdatta LA: Granular cell tumor of the toe: a case report. Dermatol Res Pract; 2010;2010

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the toe: a case report.
  • Granular cell tumor is a rare tumor of unknown etiology that more commonly affects the oral cavity but can also occur at other sites.
  • The majorities of granular cell tumors are benign and present as a singular dermal nodule.
  • We discuss a case of granular cell tumor of the fourth toe in a 54-year-old patient that was treated with conservative surgery, instead of amputation, and reconstruction with a dermal regeneration template.

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  • (PMID = 20862204.001).
  • [ISSN] 1687-6113
  • [Journal-full-title] Dermatology research and practice
  • [ISO-abbreviation] Dermatol Res Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2938433
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75. Stieglitz F, Kitz R, Schäfers HJ, Eickmeier O, Rose M, Fellbaum C, Zielen S: Granular cell tumor of the trachea in a child. Ann Thorac Surg; 2005 Feb;79(2):e15-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the trachea in a child.
  • Granular cell tumors are uncommon benign neoplasms.
  • We present the case of a 14-year-old girl with a granular cell tumor of the trachea.
  • The tumor was incidentally found at bronchoscopy performed to exclude suspected foreign body aspiration.
  • Biopsies revealed the histologic pattern of a benign granular cell tumor.
  • She has not had any recurrence of the tumor during 3 years of follow-up.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Granular Cell Tumor / surgery. Tracheal Neoplasms / diagnosis. Tracheal Neoplasms / surgery
  • [MeSH-minor] Adolescent. Biopsy. Bronchoscopy. Cough / etiology. Diagnosis, Differential. Female. Foreign-Body Reaction / diagnosis. Humans. Pneumonia, Aspiration / diagnosis

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  • (PMID = 15680798.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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76. Baloch ZW, Martin S, Livolsi VA: Granular cell tumor of the thyroid: a case report. Int J Surg Pathol; 2005 Jul;13(3):291-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the thyroid: a case report.
  • We report a rare case of granular cell tumor (GCT) arising within the thyroid parenchyma.
  • The differential diagnosis of GCT in thyroid includes all oncocytic/Hürthle cell lesions of the thyroid, medullary carcinoma and metastasis.
  • The classic histomorphologic features and immunohistochemistry are helpful in arriving at the correct diagnosis.
  • [MeSH-major] Granular Cell Tumor / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Biomarkers, Tumor / analysis. Carcinoma, Medullary / diagnosis. Carcinoma, Medullary / secondary. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged. Thyroidectomy

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  • (PMID = 16086088.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 19
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77. Godoy G, Mufarrij PW, Tsou HC, Torre P, Taneja SS: Granular cell tumor of scrotum: a rare tumor of the male external genitalia. Urology; 2008 Sep;72(3):716.e7-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of scrotum: a rare tumor of the male external genitalia.
  • We report a rare case of granular cell tumor in the scrotum.
  • Granular cell tumors are soft-tissue neoplasms originating from Schwann cells that rarely affect male external genitalia.
  • Although never previously reported in the male external genitalia, malignant variants exist in 2% of cases.
  • Because the clinical presentation is not specific, the diagnosis of malignant granular cell tumors can be made only by the pathologist.
  • [MeSH-major] Genital Neoplasms, Male / diagnosis. Genital Neoplasms, Male / pathology. Granular Cell Tumor / diagnosis. Granular Cell Tumor / pathology. Scrotum / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Humans. Male. Medical Oncology / methods. Middle Aged. Schwann Cells / pathology

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  • (PMID = 18384852.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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78. Abraham T, Jackson B, Davis L, Yu J, Peterson C: Mohs surgical treatment of a granular cell tumor on the toe of a child. Pediatr Dermatol; 2007 May-Jun;24(3):235-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mohs surgical treatment of a granular cell tumor on the toe of a child.
  • Granular cell tumors are uncommon, usually benign tumors of neural origin.
  • We report a granular cell tumor on the distal toe of a 5-year-old child, removed with Mohs surgery.
  • Review of the English language literature revealed four previously reported granular cell tumors treated with Mohs micrographic surgery, none of which was in a child.
  • [MeSH-major] Granular Cell Tumor / surgery. Mohs Surgery. Skin Neoplasms / surgery. Toes / surgery

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  • (PMID = 17542870.001).
  • [ISSN] 0736-8046
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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79. Narasimhan K, Arneja JS, Rabah R: Treatment of congenital epulis (granular cell tumour) with excision and gingivoperiosteoplasty. Can J Plast Surg; 2007;15(4):215-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of congenital epulis (granular cell tumour) with excision and gingivoperiosteoplasty.
  • Congenital epulis, or granular cell tumour, is a rare, benign intraoral tumour present on the mucosa of the alveolar ridge, with the potential to interfere with respiration and feeding.
  • The management of the alveolar deficiency associated with this tumour has not previously been addressed.
  • The differential diagnosis and complications of this tumour are discussed.

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  • (PMID = 19554180.001).
  • [ISSN] 1195-2199
  • [Journal-full-title] The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique
  • [ISO-abbreviation] Can J Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2696006
  • [Keywords] NOTNLM ; Epulis / Gingivoperiosteoplasty
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80. Bilanović D, Boricić I, Zdravković D, Randjelović T, Stanisavljević N, Toković B: Granular cell tumor of the common hepatic duct presenting as cholangiocarcinoma and acute acalculous cholecystitis. Acta Chir Iugosl; 2008;55(4):99-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the common hepatic duct presenting as cholangiocarcinoma and acute acalculous cholecystitis.
  • Granular cell tumors (GCT) are rare benign tumors.
  • Most researches favour a Schwann cell origin.
  • Firm tumor mass was found above the conjunction of cystic duct and common hepatic duct (CHD) that caused obstruction and gallblader empyema.
  • The patient underwent radical surgical procedure because Klatskin tumor was clinically suspected.
  • Patohystology and immunohistochemistry confirmed granular cell tumor.
  • Granular cell tumors are rarely diagnosed preoperatively.
  • [MeSH-major] Acalculous Cholecystitis / diagnosis. Bile Duct Neoplasms / diagnosis. Cholangiocarcinoma / diagnosis. Granular Cell Tumor / diagnosis. Hepatic Duct, Common
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans

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  • (PMID = 19245149.001).
  • [ISSN] 0354-950X
  • [Journal-full-title] Acta chirurgica Iugoslavica
  • [ISO-abbreviation] Acta Chir Iugosl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Serbia
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81. Dimosthenous K, Righi A: Granular cell tumor of the parotid gland: an exceptionally rare occurrence. Int J Surg Pathol; 2008 Apr;16(2):213-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the parotid gland: an exceptionally rare occurrence.
  • The authors report on a case of a granular cell tumor of the parotid gland, which constitutes an extremely rare neoplasm.
  • The infiltrative growth of the tumor may pose the question of malignancy, especially on frozen section.
  • [MeSH-major] Granular Cell Tumor / pathology. Parotid Gland / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnostic Errors / prevention & control. Female. Frozen Sections. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18387991.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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82. Yang WT, Edeiken-Monroe B, Sneige N, Fornage BD: Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation. J Clin Ultrasound; 2006 May;34(4):153-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation.
  • PURPOSE: To describe the sonographic and mammographic appearance of granular cell tumors (GCTs) of the breast in 6 patients with pathological correlation.
  • METHODS: A search was conducted of the cyto-histopathological database in a single institution from 1990 to 2004 for breast lesions given the diagnosis of GCT of the breast.
  • The cytomorphological features of GCT included sheets of large granular cells intersected by arborizing thin-walled blood vessels.
  • The cells had round to oval nuclei, inconspicuous nucleoli, and abundant, ill-defined granular cytoplasm.
  • [MeSH-major] Breast Neoplasms / radiography. Breast Neoplasms / ultrasonography. Carcinoma / diagnosis. Granular Cell Tumor / radiography. Granular Cell Tumor / ultrasonography. Mammography. Ultrasonography, Doppler
  • [MeSH-minor] Adolescent. Adult. Age of Onset. Diagnosis, Differential. Female. Humans. Middle Aged

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  • [Copyright] Copyright 2006 Wiley Periodicals, Inc.
  • (PMID = 16615051.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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83. Vaos G, Zavras N, Priftis K, Pierrakos P: Bronchial granular cell tumor in a child: impact of diagnostic delay on the type of surgical resection. J Pediatr Surg; 2006 Jul;41(7):1326-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bronchial granular cell tumor in a child: impact of diagnostic delay on the type of surgical resection.
  • Bronchial granular cell tumor is an uncommon tumor in young children.
  • Recurrent pneumonia in the same site should raise suspicion of an obstructing granular cell tumor of the bronchus.
  • We present a 10-year-old girl with an 18-month history of recurrent pneumonia caused by obstruction of the main lingular bronchus by this type of tumor.
  • In our patient, an upper left lobectomy was only technically feasible instead of a lingulectomy alone because of the spread pulmonary inflammation and the depth of bronchial wall invasion by the tumor.
  • Delayed diagnosis resulted in a more extensive pulmonary resection.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Granular Cell Tumor / diagnosis

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  • (PMID = 16818074.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Joung MK, Lee YJ, Chung CU, Lee JE, Jung SS, Kim SY, Kim JO: A case of granular cell tumor of the trachea. Korean J Intern Med; 2007 Jun;22(2):101-5
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  • [Title] A case of granular cell tumor of the trachea.
  • The pathologic findings showed a benign granular cell tumor.
  • The respiratory symptoms resolved after biopsying the tumor.
  • On follow up, there were no signs of recurrence of the granular cell tumor after a period of 24 months.
  • [MeSH-major] Chest Pain / diagnosis. Granular Cell Tumor / diagnosis. Hemoptysis. Tracheal Neoplasms / diagnosis

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  • [Cites] Am J Otolaryngol. 2004 Jul-Aug;25(4):270-3 [15239036.001]
  • [Cites] Tumori. 1994 Jun 30;80(3):224-8 [8053081.001]
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  • (PMID = 17616025.001).
  • [ISSN] 1226-3303
  • [Journal-full-title] The Korean journal of internal medicine
  • [ISO-abbreviation] Korean J. Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2687619
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85. Lazar AJ, Fletcher CD: Primitive nonneural granular cell tumors of skin: clinicopathologic analysis of 13 cases. Am J Surg Pathol; 2005 Jul;29(7):927-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primitive nonneural granular cell tumors of skin: clinicopathologic analysis of 13 cases.
  • A rare subset of distinctive cutaneous nonneural granular cell tumors was described by LeBoit et al in 1991 and termed "primitive polypoid granular-cell tumor."
  • Herein, we report our experience with 13 similar, distinctive nonneural granular cell tumors.
  • Clinically described as smooth, nontender cutaneous nodules, the tumors ranged in size from 0.2 to 2.8 cm (median, 0.8 cm) and were present from months to years before excision.
  • All the tumors were well circumscribed and composed of spindled to ovoid cells with abundant granular, eosinophilic cytoplasm and vesicular nuclei with small prominent nucleoli.
  • However, one tumor (case no. 11) gave rise to a local lymph node metastasis 25 months after presentation, but the patient is currently disease-free 70 months after lymphadenectomy.
  • These cutaneous granular tumors do not appear to be neural or Schwannian in nature, but their precise line of differentiation is unknown.
  • [MeSH-major] Granular Cell Tumor / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor. Child. Female. Humans. Immunohistochemistry. Lymphatic Metastasis / pathology. Male. Middle Aged. Treatment Outcome

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  • (PMID = 15958858.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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86. Kondi-Pafiti A, Kairi-Vassilatou E, Liapis A, Bakalianou K, Iavazzo Ch, Hasiakos D: Granular cell tumor of the female genital system. Clinical and pathologic characteristics of five cases and literature review. Eur J Gynaecol Oncol; 2010;31(2):222-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the female genital system. Clinical and pathologic characteristics of five cases and literature review.
  • The clinical and pathological characteristics of a rare granular cell tumor that developed in the vulva (4 cases) and the breast (1 case) offive women aged 35-52 years are reported.
  • The differential diagnosis from skin carcinomas, melanoma and various soft tissue tumors is emphasized.
  • [MeSH-major] Breast Neoplasms / pathology. Granular Cell Tumor / pathology. Vulvar Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Middle Aged. Prognosis. Treatment Outcome

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  • (PMID = 20527248.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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87. Yang JH, Mitchell KB, Poppas DP: Granular cell tumor of the glans penis in a 9-year-old boy. Urology; 2008 Mar;71(3):546.e1-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the glans penis in a 9-year-old boy.
  • Granular cell tumor of the penis is a rare lesion, especially in the pediatric population.
  • We present a case of a 9-year-old white boy with a granular cell tumor of the glans penis, as well as a review of literature.
  • [MeSH-major] Granular Cell Tumor. Penile Neoplasms

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  • (PMID = 18342206.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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88. Patti R, Almasio PL, Di Vita G: Granular cell tumor of stomach: a case report and review of literature. World J Gastroenterol; 2006 Jun 7;12(21):3442-5
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  • [Title] Granular cell tumor of stomach: a case report and review of literature.
  • Granular cell tumor (GCT) was described for the first time by Abrikosoff in 1926.
  • It is a relatively rare neoplasm that may occur at many sites, but most commonly in the skin or soft tissues.
  • The occurrence of GCT in the gastrointestinal tract is rare, accounting approximately for 8% of all tumors, among which the most common site is the esophagus, whereas gastric localization is very rare.
  • Although GCTs are usually clinically and histologically benign, some malignant cases have been reported.
  • Histologically, these tumors consist of polygonal and fusiform cells disposed in compact "nests" and immunohistochemical staining for S-100 protein supports the proposed derivation from Schwann cells.
  • A correct preoperative diagnosis of this tumor can only be made in 50% of all patients and it is always based on endoscopic biopsy.
  • In this study, the authors reported a case of a 49-year-old woman with a solitary granular cell tumor of the stomach with infiltrative pattern, successfully treated with surgical resection.
  • A review of literature is also presented with emphasis on diagnostic criteria concerning the malignant form.
  • [MeSH-major] Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Stomach Neoplasms / pathology. Stomach Neoplasms / surgery

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  • [Cites] Am J Gastroenterol. 1994 Dec;89(12):2259-60 [7977263.001]
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  • (PMID = 16733867.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / S100 Proteins
  • [Number-of-references] 17
  • [Other-IDs] NLM/ PMC4087881
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89. Epstein DS, Pashaei S, Hunt E Jr, Fitzpatrick JE, Golitz LE: Pustulo-ovoid bodies of Milian in granular cell tumors. J Cutan Pathol; 2007 May;34(5):405-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pustulo-ovoid bodies of Milian in granular cell tumors.
  • BACKGROUND: Granular cell tumors (GCTs) are benign neural tumors with a distinct histologic appearance on light microscopy, characterized by eosinophilic cytoplasmic granules.
  • METHODS: We examined the sections of 47 cases of GCT stained with hematoxylin and eosin to determine the frequency of POB within this tumor.
  • When grouped according to clinical characteristics, there was an even distribution of POB by age, sex and site of the tumor.
  • CONCLUSIONS: In our series, POB were present in varying numbers in all the tumors studied.
  • [MeSH-major] Granular Cell Tumor / pathology. Inclusion Bodies / pathology. Skin Neoplasms / pathology

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  • (PMID = 17448196.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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90. Dogramaci Y, Kalaci A, Sevinc TT, Hakverdi S, Canda S, Yanat AN: Granular cell tumor of the posterior tibial nerve as a rare cause of heel pain: a case report. J Am Podiatr Med Assoc; 2009 May-Jun;99(3):254-7
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  • [Title] Granular cell tumor of the posterior tibial nerve as a rare cause of heel pain: a case report.
  • Granular cell tumor of peripheral nerves is extremely rare.
  • We present the case of a patient with a well-capsulated intraneural granular cell tumor involving the posterior tibial nerve, who presented with chronic heel pain mimicking plantar fasciitis.
  • Histopathologic examination showed a granular cell tumor, which is extremely rare in the peripheral nerves.
  • Posterior tibial nerve lesions at the leg should be kept in mind in the differential diagnosis of patients with persistent heel and foot pain.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Heel. Pain / etiology. Peripheral Nervous System Neoplasms / diagnosis. Tibial Nerve
  • [MeSH-minor] Adult. Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male

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  • (PMID = 19448179.001).
  • [ISSN] 8750-7315
  • [Journal-full-title] Journal of the American Podiatric Medical Association
  • [ISO-abbreviation] J Am Podiatr Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Reuhl J, Fink T, Glees M, Bernd L, Fisseler-Eckhoff A: [An unusual complication after an insect bite? Diagnostic procedures in a case of granular cell tumor]. Pathologe; 2007 Jul;28(4):273-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [An unusual complication after an insect bite? Diagnostic procedures in a case of granular cell tumor].
  • Granular cell tumors are, in almost all cases, benign soft tissue tumors, although malignant variants have rarely been described in a variety of anatomical locations.
  • In the case presented here, a so-called atypical granular cell tumor was diagnosed based on two criteria, being differentiated from the usual histological findings by enhanced mitotic activity and focal spindle cell proliferation.
  • Further suspicious characters of the tumor were its size of 13x10x5 cm on MRT as well as its long-term clinical course (1.5 years).
  • The diagnostic procedures undergone until resection of the tumor, including the macroscopic and histological findings, are presented.
  • The diagnosis can be made with certainty by using conventional histology in combination with immunohistochemistry.
  • The tumor cells react positively with antibodies against S-100 protein, NSE, laminin, myelin proteins and myelin-associated glycoproteins.
  • These staining patterns underscore the neural origin of the tumor tissue.
  • In this case a mitotic frequency of two per ten high power fields and focal spindle cells led to the diagnosis of an atypical granular cell tumor, whereas the criteria for a malignant variant were not met.
  • [MeSH-major] Bites and Stings / complications. Bites and Stings / pathology. Granular Cell Tumor / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Animals. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged. Mitosis

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  • (PMID = 16555043.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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92. Daniels JS: Granular cell tumour of tongue: A case report. Saudi Dent J; 2009 Jul;21(2):75-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumour of tongue: A case report.
  • Granular cell tumour, also known as Abrikossoff tumour, is a relatively uncommon benign neoplasm, which is more commonly found in females in the 4th to 6th decades of life even though it can occur in all ages.
  • Intraoral lesions represent about 70% of the granular cell tumours of the head and neck, and account for 1/3 of all cases affecting the whole body.
  • Although majority of granular cell tumours are benign, some are clinically aggressive and a few frankly malignant forms have been reported.
  • A case of granular cell tumour which occurred on the midline area of the dorsum of the posterior 1/3 of the tongue is reported in a 20-year-old female patient.
  • It is interesting because the patient was younger than the average age of occurrence and the tumour occurred in a similar site to that of a lingual thyroid.

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  • (PMID = 23960463.001).
  • [ISSN] 1013-9052
  • [Journal-full-title] The Saudi dental journal
  • [ISO-abbreviation] Saudi Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Other-IDs] NLM/ PMC3722994
  • [Keywords] NOTNLM ; Dorsum of posterior one-third of tongue / Granular cell tumour / Lingual thyroid / Pseudoepitheliomatous hyperplasia / Squamous cell carcinoma of tongue
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93. Honda K, Tanaka S, Kishimoto M, Iwai K, Tamaki H, Asato R, Ito J: Granular cell tumor of hypopharynx: report of a rare case. Acta Otolaryngol Suppl; 2007 Feb;(557):73-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of hypopharynx: report of a rare case.
  • Granular cell tumor is a rare tumor, probably of Schwann cell origin.
  • We report the seventh case of hypopharyngeal granular cell tumor.
  • Immunohistochemical staining for S100 protein is helpful for the correct diagnosis.
  • [MeSH-major] Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Hypopharyngeal Neoplasms / pathology. Hypopharyngeal Neoplasms / surgery

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  • (PMID = 17453450.001).
  • [ISSN] 0365-5237
  • [Journal-full-title] Acta oto-laryngologica. Supplementum
  • [ISO-abbreviation] Acta Otolaryngol Suppl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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94. Mogorovich A, Giannarini G, De Maria M, Manassero F, Selli C: Granular cell tumour of the urinary bladder: a case report and review of the literature. Arch Ital Urol Androl; 2007 Mar;79(1):43-4
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  • [Title] Granular cell tumour of the urinary bladder: a case report and review of the literature.
  • Granular cell tumor of the urinary bladder is an exceedingly rare disease, with only 10 cases reported so far in literature.
  • We report a case of granular cell neoplasm of the bladder incidentally found in a 44-year-old woman during an abdominal ultrasound examination for evaluation of stress urinary incontinence.
  • The patient underwent a transurethral resection of the mass and histological examination revealed the presence of a granular cell tumor.

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  • (PMID = 17484407.001).
  • [ISSN] 1124-3562
  • [Journal-full-title] Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
  • [ISO-abbreviation] Arch Ital Urol Androl
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins; 0 / S100A1 protein; EC 4.2.1.11 / Phosphopyruvate Hydratase
  • [Number-of-references] 6
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95. Li X, Parke RB, Rushton JR, Sienko A, Zhai QJ: An unusually large granular cell tumor of the pharynx: a case report and literature review. Int J Clin Exp Pathol; 2009;2(3):300-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An unusually large granular cell tumor of the pharynx: a case report and literature review.
  • We report a granular cell tumor of the pharynx in a 53 year-old woman who presented with a large retropharyngeal mass.
  • Histologically, the tumor is composed of diffusely arranged oval and spindle cells with abundant eosinophilic granular cytoplasm and mildly pleomorphic nuclei without necrosis or mitoses.
  • Immunostains show the tumor cells to be positive for S-100, vimentin, non-specific esterase and focally positive for inhibin.
  • In addition to its unusual location, this tumor is extremely large while most granular cell tumors are small (<2 cm).
  • This case represents a unique example of a large granular cell tumor at a rare location: the pharynx.

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  • (PMID = 19079624.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2600466
  • [Keywords] NOTNLM ; Granular cell tumor / pharynx
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96. Lucendo AJ, De Rezende L, Martín-Plaza J, Larrauri J: Esophageal granular cell tumor and eosinophilic esophagitis: two interesting entities identified in the same patient. Case Rep Gastroenterol; 2008;2(1):33-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Esophageal granular cell tumor and eosinophilic esophagitis: two interesting entities identified in the same patient.
  • Endoscopy detected a submucosal tumor in the upper third of the esophagus, which was typified, via biopsy, as a granular cell tumor with benign characteristics and probably responsible for the symptoms.
  • Esophageal manometry identified a motor disorder affecting the esophageal body.
  • This is the first documented case of the link between granular cell tumors and Eosinophilic esophagitis, two different disorders which could cause dysphagia in young patients.

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  • (PMID = 21490835.001).
  • [ISSN] 1662-0631
  • [Journal-full-title] Case reports in gastroenterology
  • [ISO-abbreviation] Case Rep Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3075163
  • [Keywords] NOTNLM ; Dysphagia / Eosinophilic esophagitis / Esophagus / Granular cell tumors
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97. Nagaraj PB, Ongole R, Bhujanga-Rao BR: Granular cell tumor of the tongue in a 6-year-old girl--a case report. Med Oral Patol Oral Cir Bucal; 2006 Mar;11(2):E162-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the tongue in a 6-year-old girl--a case report.
  • Granular cell tumor is a relatively uncommon benign hamartomatous lesion occurring in almost any part of the body.
  • Granular cell lesions may be found in other diverse sites such as the jaw, skin, gastro intestinal tract and respiratory tract.
  • However, histochemical and ultra structural studies propose the origin of the lesion from schwann cells, striated muscle, mesenchymal cells, histiocytes and epithelial cells.
  • The tumor generally occurs in middle or older aged adults.
  • As most of the granular cell tumors are benign, surgical excision of the lesion is the treatment of choice.
  • We describe a case of granular cell tumor of the tongue in a 6 year old girl along with a brief review of literature on granular cell tumors.
  • [MeSH-major] Granular Cell Tumor. Tongue Neoplasms

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  • (PMID = 16505796.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 15
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98. Pérez Valcárcel J, Sánchez Arca ME, Sousa Escandón A, Uribarri González CV: [Granular cell tumour of prostate diagnosed by transrectal biopsy. Which therapeutic attitude?]. Actas Urol Esp; 2006 Nov-Dec;30(10):1031-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumour of prostate diagnosed by transrectal biopsy. Which therapeutic attitude?].
  • [Transliterated title] Tumor de células granulares de próstata diagnosticado en biopsia transrectal. Qué actitud tomar?
  • Granular cell tumour (GCT) is not an uncommon tumour of neural origin usually located on subcutaneous tissues and oral cavity.
  • The clinicpathological dilemma originated after this diagnosis is discused and the most suitable follow-up is proposed.
  • [MeSH-major] Granular Cell Tumor / pathology. Prostatic Neoplasms / pathology

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  • (PMID = 17253072.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 11
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99. Veit AC, Painter JT, Miller RA, Hardisty JF, Dixon D: Characterization of uterine granular cell tumors in B6C3F1 mice: a histomorphologic, immunohistochemical, and ultrastructural study. Vet Pathol; 2008 Sep;45(5):654-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization of uterine granular cell tumors in B6C3F1 mice: a histomorphologic, immunohistochemical, and ultrastructural study.
  • The granular cell tumor is most often a benign neoplasm of uncertain origin.
  • Four uterine granular cell tumors in control and treated female B6C3F1 mice were identified in chronic studies at the National Toxicology Program.
  • Two tumors occurred in untreated control animals and 2 in treated animals receiving different compounds.
  • The main histomorphologic feature of tumor cells was the presence of abundant cytoplasmic eosinophilic granules that stained positive for periodic acid-Schiff with diastase resistance.
  • Tumors varied in appearance and were comprised of sheets and nests of round to polygonal cells with distinct borders.
  • Occasional multinucleated giant cells were observed.
  • Tumors were pale pink and homogeneous with trichrome stain and negative with toluidine blue.
  • Three tumors had positive to weakly positive immunoreactivity for desmin, and 1 was positive for alpha smooth muscle actin.
  • Expression of S-100, wide-spectrum cytokeratin, and neuron-specific enolase was negative for all tumors.
  • The characteristics of these uterine granular cell tumors were suggestive of a myogenic origin.
  • [MeSH-major] Granular Cell Tumor / veterinary. Uterine Neoplasms / veterinary

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  • (PMID = 18725470.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z99 ES999999
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS103826; NLM/ PMC2691646
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100. Aneiros-Fernandez J, Arias-Santiago S, Husein-Elahmed H, Ovalle F, Siendones MI, Aneiros-Cachaza J: Cutaneous granular cell tumor of the breast: a clinical diagnostic pitfall. J Clin Med Res; 2010 Aug 18;2(4):185-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous granular cell tumor of the breast: a clinical diagnostic pitfall.
  • We report the clinical-morphological study of a granular cell tumor in dermal/hypodermal junction and subcutaneous fat left breast of an 83-year-old woman with a family history of breast carcinoma.
  • The histopathology study showed a proliferation of cells with ample and granular cytoplasm that were positive for S100, CD 68 and inhibin and negative for hormonal receptors.
  • KEYWORDS: Granular cell tumor; Breast; Differential diagnosis; Cutaneous.

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  • (PMID = 21629537.001).
  • [ISSN] 1918-3011
  • [Journal-full-title] Journal of clinical medicine research
  • [ISO-abbreviation] J Clin Med Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC3104657
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