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1. Tamura K, Tani M, Kinoshita H, Yamaue H: Mesenteric desmoid tumor of the interposed jejunal pouch after total gastrectomy. World J Surg Oncol; 2006;4:27
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenteric desmoid tumor of the interposed jejunal pouch after total gastrectomy.
  • BACKGROUND: Desmoid tumor is a rare entity, and most desmoid tumors are located in abdominal wall or extra-abdominal tissues.
  • Occurrence of desmoid tumor in mesentry is extremely rare.
  • CASE PRESENTATION: we report a mesenteric desmoid tumor in a 73-years-old woman who had undergone total gastrectomy reconstructed with jejunal pouch interposition for gastric carcinoma.
  • After 1 year, a tumor was originating from mesentery of the interposed jejunal pouch was identified, and the patient underwent resection of the large mass which was found to invade pancreas.
  • Histological examination revealed desmoid tumor.
  • CONCLUSION: Desmoid tumor is rare, and it was difficult for the differential diagnosis of desmoid tumor or recurrent tumor.

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  • (PMID = 16740152.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1481628
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2. Jung SH, Paik CN, Jung JH, Lee KM, Chung WC, Yang JM: Simultaneous Colonic Obstruction and Hydroureteronephrosis due to Mesenteric Fibromatosis. Gut Liver; 2009 Sep;3(3):215-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Simultaneous Colonic Obstruction and Hydroureteronephrosis due to Mesenteric Fibromatosis.
  • Mesenteric fibromatosis (MF) is a rare benign mesenchymal lesion that can occur throughout the gastrointestinal tract, especially small bowel.
  • We described a patient that presented with colonic obstruction and hydroureteronephrosis due to MF at sigmoid colon which mimicked submucosal tumor such as gastrointestinal tumor.
  • This case resulted in a positive positron emission tomography scan suggesting malignant neoplasm, but beta-catenin positivity on immunohistochemical staining separated MF from gastrointestinal stromal tumor and sclerosing mesenteritis.

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  • (PMID = 20431749.001).
  • [ISSN] 2005-1212
  • [Journal-full-title] Gut and liver
  • [ISO-abbreviation] Gut Liver
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2852704
  • [Keywords] NOTNLM ; Colonic obstruction / Hydroureteronephrosis / Mesenteric fibromatosis
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3. Choi JY, Kang KM, Kim BS, Kim TH: Mesenteric fibromatosis causing ureteral stenosis. Korean J Urol; 2010 Jul;51(7):501-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenteric fibromatosis causing ureteral stenosis.
  • Mesenteric fibromatosis is a rare benign disease characterized by proliferating fibrous tissue in the bowel mesentery.
  • We report a case of aggressive mesenteric fibromatosis with ureteral stenosis arising in a 46-year-old woman who suffered from intermittent right abdominal pain.
  • Computed tomography revealed a right retroperitoneal mass with right ureteral stenosis at the level of the right common iliac vessel.
  • Pathological examination confirmed mesenteric fibromatosis.

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  • (PMID = 20664786.001).
  • [ISSN] 2005-6745
  • [Journal-full-title] Korean journal of urology
  • [ISO-abbreviation] Korean J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2907502
  • [Keywords] NOTNLM ; Aggressive fibromatosis / Retroperitoneal neoplasms
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4. Sun L, Wu H, Zhuang YZ, Guan YS: A rare case of pregnancy complicated by mesenteric mass: what does chylous ascites tell us? World J Gastroenterol; 2007 Mar 14;13(10):1632-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of pregnancy complicated by mesenteric mass: what does chylous ascites tell us?
  • Mesenteric fibromatosis is a rare benign nonmetastatic neoplasm that appears as a sporadic lesion or occurs in patients with familial polyposis, while chylous ascites associated with aggressive mesenteric fibromatosis during pregnancy has never been reported thus far.
  • Here we present the case of a 28-year old pregnant woman, in whom an aggressive mesenteric fibromatosis with chylous ascites was detected, involving the jejunum, superior mesenteric artery (SMA) and superior mesenteric vein (SMV) and pancreas.
  • The authors report the case for its rarity and emphasize on combining clinicopathological, radiological and immunohistochemistry analysis for management of the disease.
  • [MeSH-major] Chylous Ascites / etiology. Fibromatosis, Abdominal / complications. Fibromatosis, Abdominal / diagnosis. Pregnancy Complications / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging. Mesentery / pathology. Mesentery / radiography. Peritoneal Neoplasms / complications. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / pathology. Pregnancy. Tomography, Spiral Computed

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  • (PMID = 17461463.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4146913
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5. Stoidis CN, Spyropoulos BG, Misiakos EP, Fountzilas CK, Paraskeva PP, Fotiadis CI: Surgical treatment of giant mesenteric fibromatosis presenting as a gastrointestinal stromal tumor: a case report. J Med Case Rep; 2010;4:314
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of giant mesenteric fibromatosis presenting as a gastrointestinal stromal tumor: a case report.
  • INTRODUCTION: Intra-abdominal fibromatosis, usually located at the mesenteric level, is a locally invasive tumor of fibrous origin, with no ability to metastasize, but a tendency to recur.
  • Certain non-typical cases of intra-abdominal fibromatosis with involvement of the bowel wall can be misdiagnosed because of their different biological behavior.
  • CASE PRESENTATION: We describe the case of a 64-year-old Caucasian man presenting with mesenteric fibromatosis and involvement of the bowel wall, who was treated surgically.
  • The macroscopic and microscopic appearance of the lesion mimicked a gastrointestinal stromal tumor, a tumor with potential malignant behavior.
  • CONCLUSION: It is essential to make an early and correct diagnosis in such equivocal cases, so that the appropriate treatment can be chosen and suitable patients admitted to clinical trials if appropriate.
  • New and reliable criteria for discriminating between intra-abdominal fibromatosis and gastrointestinal stromal tumor should be proposed and established because novel sophisticated therapeutic strategies have been introduced in the international literature.

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  • (PMID = 20863383.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2955058
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6. Bethune R, Amin A: Mesenteric fibromatosis: a rare cause of acute abdominal pain. Ann R Coll Surg Engl; 2006 Mar;88(2):1-2
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  • [Title] Mesenteric fibromatosis: a rare cause of acute abdominal pain.
  • A 45-year-old man, with a previous history of astrocytoma, presented with diffuse abdominal pain.
  • A CT scan was non-specific and the pain worsened; his abdomen became peritonitic on examination.
  • An exploratory laparotomy was performed, and a large small bowel mesenteric mass was found together with an associated haematoma.
  • Subsequent histology showed the tumour to be a benign fibromatosis, and the patient recovered uneventfully.
  • There were no reports in the literature of any association between astrocytomas and fibromatosis.
  • Mesenteric fibromatosis is a rare tumour often associated with Gardner's syndrome.
  • [MeSH-major] Abdominal Pain / etiology. Fibroma / complications. Ileal Diseases / complications. Mesentery
  • [MeSH-minor] Acute Disease. Astrocytoma / complications. Colonic Diseases / complications. Diagnosis, Differential. Gastrointestinal Hemorrhage / complications. Hematoma / complications. Humans. Male. Middle Aged

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  • (PMID = 16884606.001).
  • [ISSN] 1478-7083
  • [Journal-full-title] Annals of the Royal College of Surgeons of England
  • [ISO-abbreviation] Ann R Coll Surg Engl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 5
  • [Other-IDs] NLM/ PMC1963641
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7. Shindholimath VV, Kumar V, Chumber S, Bhuvnesh, Srivastava A: Mesenteric fibromatosis with involvement of the gastrointestinal tract. Trop Gastroenterol; 2006 Oct-Dec;27(4):177-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenteric fibromatosis with involvement of the gastrointestinal tract.
  • Primary mesenteric fibromatosis is a rare condition.
  • The aggressive nature of these tumors and the potential for major morbidity secondary to resection makes it a challenging disease for the surgeon.
  • We report a case of mesenteric fibromatosis with involvement of small bowel.
  • [MeSH-major] Duodenal Diseases / etiology. Fibromatosis, Abdominal / complications. Intestinal Fistula / etiology. Mesentery. Peritoneal Neoplasms / complications

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  • (PMID = 17542298.001).
  • [ISSN] 0250-636X
  • [Journal-full-title] Tropical gastroenterology : official journal of the Digestive Diseases Foundation
  • [ISO-abbreviation] Trop Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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8. Ng TY, Yang MD, Chen YF, Chang CH: Resolution of hydronephrosis due to massive mesenteric fibromatosis using cyclo-oxygenase 2 inhibitors. Urology; 2007 Sep;70(3):591.e3-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Resolution of hydronephrosis due to massive mesenteric fibromatosis using cyclo-oxygenase 2 inhibitors.
  • Mesenteric fibromatosis is currently a diagnostic and therapeutic challenge.
  • We report a case of mesenteric fibromatosis in a 29-year-old man with a 2-month history of periumbilical fullness who was discovered to have an abdominal mass with hydronephrosis.
  • To the best of our knowledge, we report the first case of hydronephrosis in a mesenteric fibromatosis with Gardner's syndrome, which was successfully treated with a cyclo-oxygenase 2 inhibitor without surgical removal of the mesenteric fibromatosis.
  • The hydronephrosis and mesenteric fibromatosis improved modestly with long-term celecoxib (200 mg twice daily).
  • [MeSH-minor] Adult. Celecoxib. Gardner Syndrome / diagnosis. Gardner Syndrome / genetics. Humans. Laparotomy. Lithotripsy. Male. Nephrostomy, Percutaneous. Ureteral Calculi / etiology. Ureteral Calculi / therapy

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  • (PMID = 17905129.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclooxygenase 2 Inhibitors; 0 / Pyrazoles; 0 / Sulfonamides; JCX84Q7J1L / Celecoxib
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9. Bertagnolli MM, Morgan JA, Fletcher CD, Raut CP, Dileo P, Gill RR, Demetri GD, George S: Multimodality treatment of mesenteric desmoid tumours. Eur J Cancer; 2008 Nov;44(16):2404-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multimodality treatment of mesenteric desmoid tumours.
  • BACKGROUND: Desmoid tumours are rare neoplasms characterised by clonal proliferation of myofibroblasts that do not metastasise, but often exhibit an infiltrative pattern and functional impairment.
  • A multidisciplinary treatment plan was developed based on primary disease extent, tumour behaviour and resectability.
  • Patients with stable but unresectable disease were observed without treatment.
  • Patients with resectable disease underwent surgery, and patients with unresectable progressing disease received chemotherapy, most commonly liposomal doxorubicin, followed by surgery if chemotherapy rendered the disease resectable.
  • RESULTS: At a median follow-up of 50.0 months (range 4.6-212), 50 patients (96%) have either no recurrence or radiographically stable disease.
  • CONCLUSION: These data indicate that the extent of disease; tumour behaviour and resectability are the important factors when defining a treatment plan for mesenteric desmoid tumours.
  • A multidisciplinary approach of surgery combined with chemotherapy is an effective and function-sparing strategy for managing this disease.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Fibromatosis, Aggressive / drug therapy. Fibromatosis, Aggressive / surgery. Mesentery. Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Doxorubicin / administration & dosage. Female. Fibromatosis, Abdominal / drug therapy. Fibromatosis, Abdominal / surgery. Humans. Male. Middle Aged. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome. Vinblastine / administration & dosage. Vinblastine / analogs & derivatives. Young Adult

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  • (PMID = 18706807.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 5V9KLZ54CY / Vinblastine; 80168379AG / Doxorubicin; Q6C979R91Y / vinorelbine
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10. Iwasa T, Sadamoto Y, Itaba S, Nasu T, Ihara Y, Misawa T, Nakamura K: [A case of mesenteric desmoid tumor]. Nihon Shokakibyo Gakkai Zasshi; 2007 Jun;104(6):804-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of mesenteric desmoid tumor].
  • Abdominal computed tomography showed a tumor, about 5 cm in diameter at the duodeno-jejunal junction.
  • The preoperative diagnosis was submucosal or mesenteric tumor.
  • The tumor derived from the mesenterium and involved the anal side of the small intestine.
  • The tumor was removed with partial excision of the upper jejunum.
  • The diagnosis of mesenteric desmoid tumor was confirmed, histologically.
  • [MeSH-major] Fibromatosis, Abdominal / diagnosis. Ileus / etiology. Mesentery. Peritoneal Neoplasms / diagnosis

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  • (PMID = 17548947.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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11. Lath C, Khanna PC, Gadewar SB, Agrawal D: Inoperable aggressive mesenteric fibromatosis with ureteric fistula. Case report and literature review. Eur J Radiol; 2006 Jul;59(1):117-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inoperable aggressive mesenteric fibromatosis with ureteric fistula. Case report and literature review.
  • The purpose of our report is to illustrate an aggressive case of mesenteric fibromatosis in a 17-year-old girl with a ureteric fistula and to review imaging and pathological features, natural history and treatment options of this disease.
  • Our patient underwent computed tomography that revealed a widespread intra-abdominal mass.
  • Fibromatoses represent a spectrum of uncommon benign conditions characterised by proliferating fibrous tissue.
  • The deep intra-abdominal form of mesenteric fibromatosis (MF), one of the rare subtypes of the 'fibromatoses' or 'desmoid tumours', grows rapidly and may become extensive.
  • Surgery provides good results in limited disease and non-surgical modalities in cases of unresectable and residual disease.
  • [MeSH-major] Fibromatosis, Abdominal / radiography. Fibromatosis, Aggressive / radiography. Mesentery / pathology. Tomography, X-Ray Computed. Ureteral Diseases / radiography. Urinary Fistula / radiography


12. Ballardini P, Gulmini L, Margutti G, Lelli G: Mesenteric fibromatosis in a patient with Camurati-Engelmann disease. A case report and literature review. Tumori; 2005 Nov-Dec;91(6):552-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenteric fibromatosis in a patient with Camurati-Engelmann disease. A case report and literature review.
  • Mesenteric fibromatosis is a rare type of desmoid tumor characterized by local aggressiveness and a tendency to relapse.
  • Camurati-Engelmann disease is a very rare form of bone dysplasia characterized by osteosclerosis of the diaphyses of the long bones.
  • Here we describe the case of a male patient affected by these two rare diseases in association with chronic inflammatory intestinal disease.


13. Huerta S, Heubner DR, Marcus DR: Mesenteric fibromatosis in a young girl without familial adenomatous polyposis. J Pediatr Surg; 2005 May;40(5):e33-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenteric fibromatosis in a young girl without familial adenomatous polyposis.
  • Mesenteric fibromatosis (MF) is a rare, benign tumor commonly associated with Gardner's syndrome.
  • Patients may present with abdominal pain or discomfort when the tumors reach large sizes, which is typical at the time of diagnosis.
  • [MeSH-major] Fibromatosis, Aggressive / surgery. Omentum / surgery. Peritoneal Diseases / surgery


14. Batori M, Chatelou E, Mariotta G, Sportelli G, Straniero A, Casella G, Casella MC: Giant mesenteric fibromatosis. Eur Rev Med Pharmacol Sci; 2005 Jul-Aug;9(4):223-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant mesenteric fibromatosis.
  • Mesenteric fibromatosis is a proliferative fibroblastic neoplasia of the small intestine mesentery which may occur as a unique or multiple formation.
  • Mesenteric fibromatosis represents the 8% of all desmoid neoplasm.
  • Giant mesenteric fibromatosis is uncommon by itself (2-4 case/milion/year).
  • Since the rarity of this tumor and the difficulties in diagnostic and therapeutic ambit, we believe it justified to describe a case of giant mesenteric fibromatosis which came to our observation.

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  • (PMID = 16128042.001).
  • [ISSN] 1128-3602
  • [Journal-full-title] European review for medical and pharmacological sciences
  • [ISO-abbreviation] Eur Rev Med Pharmacol Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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15. Perenze B, Potì O, Margiotta A, Rega D, Marrano N, Minni F: [Mesenteric fibromatosis]. Chir Ital; 2005 Nov-Dec;57(6):717-22
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  • [Title] [Mesenteric fibromatosis].
  • [Transliterated title] La fibromatosi mesenterica.
  • Mesenteric fibromatosis is a rare benign mesenteric tumour, characterised by infiltrative growth and high rates of recurrence.
  • Histological examination is the only diagnostic procedure capable of ruling out a malignant mesenteric neoplasm.
  • It is not always possible to perform a radical removal of the tumour mass because it may have infiltrated important anatomical structures.
  • In the present study the Authors report two cases of mesenteric fibromatosis and analyse the main clinical-diagnostic, therapeutic and prognostic problems posed by these tumours.

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  • (PMID = 16400766.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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16. Holubar S, Dwivedi AJ, O'Connor J: Giant mesenteric fibromatosis presenting as small bowel obstruction. Am Surg; 2006 May;72(5):427-9
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  • [Title] Giant mesenteric fibromatosis presenting as small bowel obstruction.
  • Mesenteric fibromatosis is a proliferative fibroblastic neoplasia of the small intestine mesentery that may occur as a unique or multiple formation.
  • Mesenteric fibromatosis is a rare, locally aggressive neoplasm and may present with abdominal discomfort, abdominal pain, weight loss, or symptoms of ureteral obstruction, mesenteric ischemia, or intestinal obstruction.
  • It is of the utmost importance to distinguish mesenteric fibromatosis from gastrointestinal stromal tumors.
  • The involvement of important structures like the superior mesenteric artery and the superior mesenteric vein may pose a challenge during resection, but these tumors can be excised and the vessels repaired primarily.
  • [MeSH-major] Fibromatosis, Abdominal / complications. Fibromatosis, Abdominal / diagnosis. Intestinal Obstruction / etiology
  • [MeSH-minor] Diagnosis, Differential. Gastrointestinal Stromal Tumors / pathology. Humans. Male. Mesentery. Middle Aged. Neoplasm Invasiveness

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  • (PMID = 16719198.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. McCormack D, Kesha K, Tittle SL, Saldinger PF: Mesenteric fibromatosis mimicking a gastrointestinal stromal tumor. Conn Med; 2010 Apr;74(4):197-200
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  • [Title] Mesenteric fibromatosis mimicking a gastrointestinal stromal tumor.
  • Mesenteric fibromatosis is a locally aggressive tumor of the mesentery with a high propensity for bowel involvement.
  • Mesenteric fibromatosis often mimics gastrointestinal stromal tumors in size, location and immunohistochemical features.
  • We report the case of a 30-year-old male who underwent resection of a mesenteric tumor, initially diagnosed as gastrointestinal stromal tumor.
  • The tumor was categorized as high-risk and the patient was treated with chemotherapy.
  • The tumor did not respond to medical management.
  • The patient underwent a second en bloc resection and pathology results were conclusive for mesenteric fibromatosis.
  • This case highlights the significance of accurately differentiating mesenteric fibromatosis from gastrointestinal stromal tumor.
  • Making a concrete diagnosis is often difficult because both gastrointestinal stromal tumors and mesenteric fibromatosis share a number of morphological and immunohistochemical features including CKIT expression.
  • [MeSH-major] Diagnostic Errors. Fibromatosis, Abdominal / diagnosis. Gastrointestinal Stromal Tumors / diagnosis
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Diagnosis, Differential. Humans. Male

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  • (PMID = 20440999.001).
  • [ISSN] 0010-6178
  • [Journal-full-title] Connecticut medicine
  • [ISO-abbreviation] Conn Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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18. Schlemmer M: Desmoid tumors and deep fibromatoses. Hematol Oncol Clin North Am; 2005 Jun;19(3):565-71, vii-viii
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  • [Title] Desmoid tumors and deep fibromatoses.
  • Desmoid tumors (also called deep fibromatoses) are rare benign tumors associated with pregnancy and Gardner syndrome.
  • They arise in the abdominal cavity, in the abdominal wall, or in the extremities/trunk, each with a slightly different biologic behavior.
  • This article highlights the biology and clinical features of desmoid tumors.
  • [MeSH-major] Fibromatosis, Aggressive. Gardner Syndrome

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  • (PMID = 15939197.001).
  • [ISSN] 0889-8588
  • [Journal-full-title] Hematology/oncology clinics of North America
  • [ISO-abbreviation] Hematol. Oncol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 44
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19. Colović R, Grubor N, Radak V, Micev M, Stojković M, Colović N: [Aggressive intraabdominal fibromatosis]. Vojnosanit Pregl; 2006 Sep;63(9):839-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Aggressive intraabdominal fibromatosis].
  • BACKGROUND: Intraabdominal or mesenteric fibromatosis is a rare benign nonmetastatic neoplasm that appears as a sporadic lesion or in patients with familiar polyposis.
  • CASE REPORT: We presented a 22-year-old woman in whom an aggressive intraabdominal fibromatosis had appeared during the first pregnancy as a well circumscribed ovoid tumor, involving the terminal ileum, the caecum, the ascending colon, the right kidney, the ureter, and the right common iliac artery.
  • The tumor was excised with right colectomy, nephroureterectomy and resection of the involved artery using arterial reconstruction with graft interposition.
  • Two years after the surgery the patient developed an inoperable tumor recurrency with a fatal outcome.
  • CONCLUSION: In spite of a successful surgical excision during the original surgery intraabdominal or mesenteric fibromatosis might have an aggressive evolution leading to an inoperable tumor recurrency and a fatal outcome.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Fibromatosis, Aggressive / pathology. Neoplasm Recurrence, Local. Pregnancy Complications, Neoplastic / pathology


20. Basu S, Nair N, Banavali S: Uptake characteristics of fluorodeoxyglucose (FDG) in deep fibromatosis and abdominal desmoids: potential clinical role of FDG-PET in the management. Br J Radiol; 2007 Sep;80(957):750-6
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  • [Title] Uptake characteristics of fluorodeoxyglucose (FDG) in deep fibromatosis and abdominal desmoids: potential clinical role of FDG-PET in the management.
  • In this preliminary report, we explore the uptake pattern of fluorodeoxyglucose (FDG) in fibromatosis and hypothesize the potential clinical role of FDG-positron emission tomography (PET) in the management of this benign but locally aggressive heterogeneous group of soft-tissue tumours.
  • Five patients were studied (two men and three women, age range 23-35 years), among whom were three cases of deep musculoskeletal fibromatosis, one of abdominal fibromatosis (abdominal desmoid) associated with familial adenomatous polyposis (Gardner's syndrome) and one case of both deep musculoskeletal fibromatosis and abdominal desmoid.
  • The maximum standardized uptake value (SUV(max)) observed was up to 4.7; the avidity probably related to the biological aggressiveness and tendency for recurrence, characteristic of fibromatosis.
  • Hence, a baseline FDG-PET can serve a valuable role in monitoring the effect of systemic pharmacotherapy in patients with recurrent progressive disease after unsuccessful local-regional treatment.
  • The findings in this report can be extrapolated and have implications for studying the utility of FDG-PET in defining aggressiveness, guiding biopsy and defining excision site in a large tumour and in monitoring therapy in fibromatosis.
  • [MeSH-minor] Adult. Female. Fibromatosis, Abdominal / complications. Fibromatosis, Abdominal / radiography. Fibromatosis, Abdominal / radionuclide imaging. Gardner Syndrome / complications. Humans. Male. Positron-Emission Tomography. Recurrence. Retrospective Studies

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  • (PMID = 17709361.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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21. Eren S: A sporadic abdominal desmoid tumour case presenting with intermittent intestinal obstruction. Eur J Pediatr Surg; 2005 Jun;15(3):196-9
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  • [Title] A sporadic abdominal desmoid tumour case presenting with intermittent intestinal obstruction.
  • Desmoid tumours, also known as aggressive fibromatoses, are rare lesions having intermediate biological behaviour between benign fibrous lesions and fibrosarcomas.
  • Although abdominal desmoids have an increased incidence in Gardner's syndrome, they are rarely found in isolated form.
  • Although intraabdominal desmoids are usually detected as a solitary lesion in sporadic cases, the case presented here had two mesenteric lesions in the left upper quadrant.
  • [MeSH-major] Fibromatosis, Aggressive / diagnosis. Intestinal Obstruction / complications. Mesentery. Peritoneal Neoplasms / diagnosis

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  • (PMID = 15999314.001).
  • [ISSN] 0939-7248
  • [Journal-full-title] European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie
  • [ISO-abbreviation] Eur J Pediatr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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22. Rajesh A, Sandrasegaran K: Mesenteric desmoid mimicking recurrent testicular cancer. Abdom Imaging; 2005 Nov-Dec;30(6):777-9
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  • [Title] Mesenteric desmoid mimicking recurrent testicular cancer.
  • The detection of a solid abdominal mass after surgery for testicular cancer most frequently represents metastatic disease.
  • We report an unusual case of mesenteric desmoid tumor presenting after retroperitoneal lymph node dissection for metastatic testicular cancer.
  • [MeSH-major] Fibromatosis, Aggressive / radiography. Mesentery. Neoplasm Recurrence, Local / radiography. Peritoneal Neoplasms / radiography. Testicular Neoplasms / radiography

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  • (PMID = 16096867.001).
  • [ISSN] 0942-8925
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Murphey MD, Ruble CM, Tyszko SM, Zbojniewicz AM, Potter BK, Miettinen M: From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics; 2009 Nov;29(7):2143-73
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  • [Title] From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation.
  • Musculoskeletal fibromatoses represent a wide spectrum of fibroblastic and myofibroblastic neoplasms with similar pathologic appearances and variable clinical behavior.
  • Superficial fibromatoses in adults (palmar and plantar) and children (calcifying aponeurotic fibroma, lipofibromatosis, and inclusion body fibromatosis) are often small slow-growing lesions; their diagnosis is suggested by location.
  • Deep fibromatoses in adults (desmoid type and abdominal wall) and children (fibromatosis colli and myofibroma and myofibromatosis) are frequently large and more rapidly enlarging; location of these lesions may be nonspecific.
  • MR imaging findings of predominantly low to intermediate signal intensity, nonenhancing bands of low signal intensity on long repetition time MR images that represent collagenized regions, and extension along fascial planes ("fascial tail" sign) add specificity for diagnosis.
  • Additional features that aid in diagnostic specificity include an abdominal wall location related to pregnancy (abdominal wall fibromatosis), a lower neck location in a young child (fibromatosis colli), an adipose component (lipofibromatosis), or multiple lesions in young children (myofibromatosis).
  • Treatment may be conservative or surgical resection, depending on the specific diagnosis.
  • Recognition that the appearances of the various types of musculoskeletal fibromatoses reflect their pathologic characteristics improves radiologic assessment and helps optimize patient management.
  • [MeSH-major] Bone Diseases / diagnosis. Fibroma / diagnosis. Magnetic Resonance Imaging. Muscular Diseases / diagnosis

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  • (PMID = 19926768.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Spiridakis K, Panagiotakis G, Grigoraki M, Kokkinos I, Papadakis T, Kokkinakis T, Kandylakis S: Isolated giant mesenteric fibromatosis (intra-abdominal desmoid tumors). Case report. G Chir; 2008 Oct;29(10):413-6
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  • [Title] Isolated giant mesenteric fibromatosis (intra-abdominal desmoid tumors). Case report.
  • A rare case of isolated giant mesenteric fibromatosis is presented.
  • The tumor originated from the fibrous mesenteric tissue.
  • The patient underwent laparotomy because of abdominal discomfort and sub-occlusive symptoms due to the giant mass.
  • Differential diagnosis of mesenteric masses is discussed and the Authors also review the literature concerning this rare disease.
  • [MeSH-major] Fibromatosis, Abdominal / diagnosis. Fibromatosis, Abdominal / surgery. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / surgery
  • [MeSH-minor] Adult. Diagnosis, Differential. Fibromatosis, Aggressive / diagnosis. Fibromatosis, Aggressive / surgery. Humans. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18947463.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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25. Rajakannu M, Ananthakrishnan N, Madhavan M: Isolated mesenteric fibromatosis. Trop Gastroenterol; 2008 Jul-Sep;29(3):179-80
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  • [Title] Isolated mesenteric fibromatosis.
  • Fibromatosis is a rare, locally aggressive but non-metastasising fibrous mass often associated with familial adenomatous polyposis in Gardner's Syndrome (GS).
  • Although sporadic cases occur, unlike in GS, they are predominantly extra-abdominal.
  • We report the case of a 40-year-old lady who underwent laparotomy for a large isolated abdominal mass three years after a Whipple's procedure for adenocarcinoma of the distal common bile duct.
  • A spherical, football sized tumour was found in the jejunal mesentery.
  • Resection of the tumour with jejunum was carried out.
  • This case is peculiar in that mesenteric fibromatosis occurred in a patient with prior history of periampullary carcinoma and without history of familial adenomatous polyposis.
  • [MeSH-major] Fibroma / diagnosis. Jejunal Neoplasms / diagnosis

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  • (PMID = 19115615.001).
  • [ISSN] 0250-636X
  • [Journal-full-title] Tropical gastroenterology : official journal of the Digestive Diseases Foundation
  • [ISO-abbreviation] Trop Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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26. Ezumi K, Yamamoto H, Takemasa I, Nomura M, Ikeda M, Sekimoto M, Monden M: Dacarbazine-Doxorubicin therapy ameliorated an extremely aggressive mesenteric desmoid tumor associated with familial adenomatous polyposis: report of a case. Jpn J Clin Oncol; 2008 Mar;38(3):222-6
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  • [Title] Dacarbazine-Doxorubicin therapy ameliorated an extremely aggressive mesenteric desmoid tumor associated with familial adenomatous polyposis: report of a case.
  • After 10 months, we found an intra-abdominal tumor, which grew rapidly to 25 cm in diameter.
  • We performed an emergency operation, which revealed that it was a desmoid tumor derived mainly from colorectal mesenterium.
  • The tumor was removed with three short segments of intestine and the left ureter.
  • A computed tomography (CT) scan done 3 months later showed a 10 cm mesenteric desmoid tumor at the beginning of jejunum, approaching the root of the superior mesenteric artery (SMA).
  • Fortunately, we were able to remove the tumor without injuring the SMA.
  • To our distress, however, another recurrent mesenteric desmoid tumor was discovered in the pelvis one month later, which grew rapidly from 5 cm to 16 cm within 4 months.
  • Finally, when the desmoid occupied the pelvic space, we gave the patient dacarbazine (DTIC) and doxorubicin (DOX).
  • After seven courses, the mesenteric tumor showed an almost complete response (CR).
  • No evidence of further recurrence of mesenteric desmoid has been seen for 4 years.
  • This combination chemotherapy is a promising strategy, even against an extremely aggressive, life-threatening mesenteric desmoid associated with FAP.
  • [MeSH-major] Adenomatous Polyposis Coli / complications. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Dacarbazine / administration & dosage. Doxorubicin / administration & dosage. Fibromatosis, Aggressive / drug therapy. Mesentery. Peritoneal Neoplasms / drug therapy

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  • (PMID = 18304951.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 094ZI81Y45 / Tamoxifen; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; 8A1O1M485B / Imatinib Mesylate
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27. Schlager A, Altchek A, Kalir T, Deligdisch L, Weber KJ: Mesenteric fibromatosis masquerading as an ovarian neoplasm twenty years after Chernobyl radiation exposure. Gynecol Oncol; 2006 Sep;102(3):587-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenteric fibromatosis masquerading as an ovarian neoplasm twenty years after Chernobyl radiation exposure.
  • BACKGROUND: Since their initial description in 1832, desmoid tumors have been reported to occur in virtually every part of the body.
  • Intra-abdominal desmoid tumors, or mesenteric fibromatosis, are often associated with Familial Adenomatous Polyposis mutation in a syndrome known as Gardner's Syndrome.
  • Although sporadic cases of desmoid tumors do occur, unlike Gardner's Syndrome, they predominantly occur extra-abdominally.
  • CASE: Case report of a 61-year-old female who presented with two months of abdominal pain, progressive lower abdominal distension and a 10-15 pound weight gain accompanied by one week of urinary hesitancy and frequency.
  • Patient underwent a diagnostic workup for an ovarian neoplasm, but was found at surgery to have mesentric fibromatosis.
  • CONCLUSION: Although uncommon, mesentric fibromatosis must be considered in the differential diagnosis when evaluating a patient with an abdominal mass of unknown origin.
  • [MeSH-major] Fibromatosis, Abdominal / diagnosis. Fibromatosis, Aggressive / diagnosis. Ovarian Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Power Plants. Radioactive Hazard Release. Ukraine

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  • (PMID = 16678243.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Seinfeld J, Kleinschmidt-Demasters BK, Tayal S, Lillehei KO: Desmoid-type fibromatoses involving the brachial plexus: treatment options and assessment of c-KIT mutational status. J Neurosurg; 2006 May;104(5):749-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoid-type fibromatoses involving the brachial plexus: treatment options and assessment of c-KIT mutational status.
  • OBJECT: Desmoid-type fibromatoses are a locally invasive soft-tissue lesion that is most commonly encountered in abdominal sites.
  • The tumor also affects head and neck areas, particularly the supraclavicular region, where it may encase and distort the brachial plexus and compromise neurovascular structures.
  • Neurosurgeons may be called on to treat desmoid-type fibromatoses in these sites.
  • The authors describe their experience in treating four patients with desmoid-type fibromatoses involving the brachial plexus and report the results of immunohistochemical analysis of the tumors.
  • Intraoperative identification of the site of tumor origin from musculoaponeurotic tissues by the neurosurgeon was necessary in two of the four cases to achieve a correct frozen section or final pathological diagnosis.
  • Immunostaining for c-KIT (CD117) was undertaken in all cases in light of a previous report of positive CD117 immunoreactivity in abdominal desmoid-type fibromatoses.
  • With the combination of surgery and radiation therapy, local disease control was achieved in three of the four patients.
  • CONCLUSIONS: This represents the first report of c-KIT sequencing in desmoid-type fibromatoses and suggests a possible biological basis for continuing to explore the use of adjuvant imatinib mesylate therapy.
  • [MeSH-major] Brachial Plexus Neuropathies / surgery. DNA Mutational Analysis. Fibromatosis, Aggressive / surgery. Peripheral Nervous System Neoplasms / surgery. Proto-Oncogene Proteins c-kit / genetics
  • [MeSH-minor] Adult. Base Pair Mismatch / genetics. Benzamides. Brachial Plexus / pathology. Brachial Plexus / surgery. Chemotherapy, Adjuvant. Combined Modality Therapy. Exons / genetics. Female. Humans. Imatinib Mesylate. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / genetics. Neoplasm Recurrence, Local / surgery. Piperazines / therapeutic use. Polymerase Chain Reaction. Pyrimidines / therapeutic use. Reoperation

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  • [CommentIn] J Neurosurg. 2007 Aug;107(2):473-5; author reply 475 [17695408.001]
  • (PMID = 16703880.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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29. Shah M, Azam B: Case report of an intra-abdominal desmoid tumour presenting with bowel perforation. Mcgill J Med; 2007 Jul;10(2):90-2
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  • [Title] Case report of an intra-abdominal desmoid tumour presenting with bowel perforation.
  • Desmoid tumours are benign tumours originating from the musculoaponeurotic structures of the body.
  • Here we present a case report of a young gentleman who presented with an acute surgical abdomen and subsequently underwent a laparotomy and was found to have an inflammatory mass.
  • Histological analysis of this mass revealed mesenteric fibromatosis (desmoid tumour).
  • It is rare for mesenteric fibromatosis to present with intestinal perforation and only one case been reported in the literature thus far (1).

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  • [Cites] Front Radiat Ther Oncol. 2001;35:107-19 [11351941.001]
  • [Cites] Arch Pathol. 1961 Feb;71:214-21 [13706852.001]
  • [Cites] Am J Gastroenterol. 1992 Oct;87(10):1503-5 [1415113.001]
  • [Cites] Dis Colon Rectum. 2005 Jun;48(6):1275-81 [15793634.001]
  • [Cites] Am J Clin Oncol. 2005 Apr;28(2):211-5 [15803019.001]
  • [Cites] Dig Dis Sci. 2006 Jan;51(1):68-9 [16416214.001]
  • [Cites] Int J Clin Oncol. 2006 Apr;11(2):150-2 [16622751.001]
  • [Cites] Surgeon. 2006 Apr;4(2):114-6 [16623170.001]
  • (PMID = 18523540.001).
  • [ISSN] 1201-026X
  • [Journal-full-title] McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students
  • [ISO-abbreviation] Mcgill J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2323473
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30. Speake D, Evans DG, Lalloo F, Scott NA, Hill J: Desmoid tumours in patients with familial adenomatous polyposis and desmoid region adenomatous polyposis coli mutations. Br J Surg; 2007 Aug;94(8):1009-13
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  • [Title] Desmoid tumours in patients with familial adenomatous polyposis and desmoid region adenomatous polyposis coli mutations.
  • BACKGROUND: :The aim of this study was to determine the proportion of patients with familial adenomatous polyposis (FAP) who had mutations in the desmoid region of the adenomatous polyposis coli (APC) gene that phenotypically expresses desmoid disease, and to determine the role for surgery in these patients.
  • RESULTS: Of 363 patients with FAP, 47 from ten families had APC mutations in the desmoid region 3' to codon 1399.
  • Of 22 patients undergoing surgery, 16 developed desmoids, and of these 12 had mesenteric desmoid disease.
  • Complications from mesenteric desmoids were death (two patients), enterectomy (three), local resection (three), fistula (one), cholangitis and local resection (one), bowel obstruction (one) and bowel and ureteric obstruction (one).
  • CONCLUSION: In individuals with 3' APC mutations, abdominal surgery is associated with a 65 per cent risk of developing mesenteric desmoids.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Fibromatosis, Aggressive / genetics. Genes, APC. Mesentery. Mutation / genetics. Peritoneal Neoplasms / genetics

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  • [Copyright] Copyright (c) 2007 British Journal of Surgery Society Ltd.
  • (PMID = 17410559.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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31. Levy AD, Rimola J, Mehrotra AK, Sobin LH: From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics; 2006 Jan-Feb;26(1):245-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Mesenteric fibromatosis, sclerosing mesenteritis, inflammatory pseudotumor, and extrapleural solitary fibrous tumor constitute a loosely associated group of benign fibrous tumors and tumorlike lesions of the mesentery.
  • Mesenteric fibromatosis is a locally aggressive, benign proliferative process that may occur sporadically or in association with familial adenomatous polyposis.
  • It most frequently manifests as a focal mesenteric mass and may simulate lymphoma, metastatic disease, or a soft-tissue sarcoma.
  • Sclerosing mesenteritis is a rare idiopathic disorder that most commonly produces a stellate mass within the mesentery and should be differentiated from metastatic disease, specifically metastatic carcinoid, because it frequently responds to conservative or medical management.
  • Inflammatory pseudotumor (inflammatory myofibroblastic tumor) is a benign, chronic inflammatory disorder of unknown cause that manifests as a solid mesenteric mass, indistinguishable from malignancy.
  • Extrapleural solitary fibrous tumor is a tumor of submesothelial origin that is identical to the solitary fibrous tumor of the pleura.
  • When located in the mesentery or peritoneal cavity, extrapleural solitary fibrous tumor has an imaging pattern that must be differentiated from metastatic disease, soft-tissue sarcomas, and other benign and malignant neoplasms of the mesentery and peritoneum.
  • Knowledge of this group of benign fibrous tumors and tumorlike lesions of the mesentery is important in the preoperative evaluation of a mesenteric mass.
  • [MeSH-major] Mesentery. Peritoneal Diseases / diagnosis. Peritoneal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child. Female. Fibroma / diagnosis. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Panniculitis, Peritoneal / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 16418255.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 57
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32. Whittle P C, Sánchez R L, Albarracin G J, Hepp K J: [Retroperitoneal fibromatosis: report of a case]. Rev Med Chil; 2006 Jan;134(1):85-9
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  • [Title] [Retroperitoneal fibromatosis: report of a case].
  • [Transliterated title] Fibromatosis mesentérica: caso clínico-imagenológico y revisión bibliográfica.
  • We report a 42 years old female that presented with abdominal pain and no palpable mass.
  • Imaging abdominal ultrasound, CAT scan and magnetic resonance showed a solid tumor located in the retroperitoneum.
  • The patient was operated on excising the tumor.
  • Pathological examination of the surgical piece disclosed a retroperitoneal fibromatosis or desmoid tumor.
  • [MeSH-major] Fibromatosis, Abdominal / diagnosis. Retroperitoneal Neoplasms / diagnosis

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  • (PMID = 16532167.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Chile
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33. Sudan D, DiBaise J, Torres C, Thompson J, Raynor S, Gilroy R, Horslen S, Grant W, Botha J, Langnas A: A multidisciplinary approach to the treatment of intestinal failure. J Gastrointest Surg; 2005 Feb;9(2):165-76; discussion 176-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fifty patients (children=30, adults=20) underwent surgical procedures to restore intestinal continuity (n=5), repair enterocutaneous fistulas (n=5), resect dysmotile or strictured/obstructed bowel segments or mesenteric desmoid tumors (n=7), stricturoplasty (n=2), Bianchi tapering and lengthening (n=20), serial transverse enteroplasty (n=8), and other operations (n=8).
  • Patient deaths occurred primarily in those listed or eligible for transplantation and were related to advanced liver disease (n=3), gastrointestinal hemorrhage (n=1), or line sepsis (n=1).

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  • (PMID = 15694812.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Eren S: A sporadic abdominal desmoid tumour case presenting with intermittent intestinal obstruction. Eur J Pediatr Surg; 2007 Aug;17(4):285-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A sporadic abdominal desmoid tumour case presenting with intermittent intestinal obstruction.
  • Desmoid tumours, also known as aggressive fibromatosis, are rare lesions with an intermediate biological behaviour between benign fibrous lesions and fibrosarcomas.
  • Although abdominal desmoids have an increased incidence in Gardner's syndrome, they are rarely found in an isolated form.
  • We report the findings of a barium study, ultrasound, computed tomography and magnetic resonance imaging in a nine-year-old boy with intermittent nausea and vomiting, diagnosed as having a desmoid tumour.
  • Although intra-abdominal desmoids are usually detected as a solitary lesion in sporadic cases, the presented case had two mesenteric lesions in the left upper quadrant.
  • [MeSH-major] Abdominal Neoplasms / complications. Digestive System Surgical Procedures / methods. Fibromatosis, Aggressive / complications. Intestinal Obstruction / etiology
  • [MeSH-minor] Child. Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 17806029.001).
  • [ISSN] 0939-7248
  • [Journal-full-title] European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie
  • [ISO-abbreviation] Eur J Pediatr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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35. Rakha EA, Kandil MA, El-Santawe MG: Gigantic recurrent abdominal desmoid tumour: a case report. Hernia; 2007 Apr;11(2):193-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gigantic recurrent abdominal desmoid tumour: a case report.
  • Deeply seated fibromatosis or desmoid tumour (DT) is a rare entity characterized by benign proliferation of fibroblasts.
  • Although non-malignant, this tumour can be life-threatening due to its invasive property and high recurrence rate.
  • We report a unique case of a huge recurrent abdominal DT (36 cm in diameter, 25 kg in weight) that caused pressure necrosis and sloughing of the overlying anterior abdominal wall, and produced a large fungating mass protruding outside the abdomen.
  • Although preoperative neoadjuvant therapies were all ineffective, radical surgical removal of the tumour was successful.
  • The procedure was followed by an excellent clinical recovery and the patient is still alive with no evidence of recurrent disease after a 6-year follow-up.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 17149531.001).
  • [ISSN] 1265-4906
  • [Journal-full-title] Hernia : the journal of hernias and abdominal wall surgery
  • [ISO-abbreviation] Hernia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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36. Coco DP, Hirsch MS, Hornick JL: Smoothelin is a specific marker for smooth muscle neoplasms of the gastrointestinal tract. Am J Surg Pathol; 2009 Dec;33(12):1795-801
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The purpose of this study was to determine whether immunostaining for smoothelin could help distinguish smooth muscle neoplasms from their morphologic mimics, particularly KIT-negative gastrointestinal stromal tumors (GISTs), desmin-positive GISTs, and desmoid fibromatosis.
  • A total of 150 mesenchymal neoplasms of the GI tract, abdominal cavity, and retroperitoneum were retrieved from consult and surgical pathology archives, including 54 GISTs (8 KIT-negative; 13 desmin-positive), 17 GI leiomyosarcomas (LMS), 11 GI mural leiomyomas, 13 leiomyomas of the muscularis mucosae, 12 gastric schwannomas, 15 inflammatory myofibroblastic tumors, 9 cases of mesenteric desmoid fibromatosis, 10 dedifferentiated liposarcomas, and 9 malignant peripheral nerve sheath tumors.
  • None of the GISTs, desmoid tumors, inflammatory myofibroblastic tumors, schwannomas, dedifferentiated liposarcomas, or malignant peripheral nerve sheath tumors showed cytoplasmic reactivity for smoothelin.
  • Nuclear expression of smoothelin was not detected in any of the other tumor types examined.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cytoskeletal Proteins / analysis. Gastrointestinal Neoplasms / chemistry. Muscle Proteins / analysis. Smooth Muscle Tumor / chemistry
  • [MeSH-minor] Cell Differentiation. Cell Nucleus / chemistry. Cytoplasm / chemistry. Desmin / analysis. Diagnosis, Differential. Humans. Immunohistochemistry. Neoplasm Staging. Predictive Value of Tests. Proto-Oncogene Proteins c-kit / analysis. Sensitivity and Specificity

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  • (PMID = 19950405.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cytoskeletal Proteins; 0 / Desmin; 0 / Muscle Proteins; 0 / SMTN protein, human; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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37. Tulchinsky H, Keidar A, Strul H, Goldman G, Klausner JM, Rabau M: Extracolonic manifestations of familial adenomatous polyposis after proctocolectomy. Arch Surg; 2005 Feb;140(2):159-63; discussion 164
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Twelve patients had 14 desmoid tumors: 7 were treated surgically and 7 medically (these patients received celecoxib and tamoxifen citrate therapy).
  • Two patients died--one of a huge mesenteric desmoid tumor and the other of an aggressive mesenteric malignant fibrous histiocytoma.
  • CONCLUSIONS: Long-term morbidity and mortality were strongly related to the development of mesenteric tumors and ampullary-duodenal polyps.
  • Early detection of desmoid tumors, duodenal, pouch, and rectal cuff adenomas by periodic computed tomography, gastroduodenoscopy, and pouchoscopy, respectively, may allow control by medical therapy, endoscopy, or limited surgical procedures.
  • In most patients control of desmoid tumors was achieved using a combination of celecoxib and tamoxifen citrate therapy.
  • [MeSH-minor] Adolescent. Adult. Celecoxib. Colorectal Neoplasms / drug therapy. Colorectal Neoplasms / radiography. Comorbidity. Drug Therapy, Combination. Endoscopy, Digestive System. Female. Fibromatosis, Aggressive / drug therapy. Fibromatosis, Aggressive / radiography. Fibromatosis, Aggressive / surgery. Humans. Male. Middle Aged. Pyrazoles / therapeutic use. Retrospective Studies. Sulfonamides / therapeutic use. Tamoxifen / therapeutic use

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  • (PMID = 15723997.001).
  • [ISSN] 0004-0010
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Pyrazoles; 0 / Sulfonamides; 094ZI81Y45 / Tamoxifen; JCX84Q7J1L / Celecoxib
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38. Sakorafas GH, Nissotakis C, Peros G: Abdominal desmoid tumors. Surg Oncol; 2007 Aug;16(2):131-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abdominal desmoid tumors.
  • Desmoid tumors are rare, benign, fibromatous lesions that are the result of abnormal proliferation of myofibroblasts.
  • Desmoid tumors can be classified as extra-abdominal and abdominal.
  • Abdominal desmoid tumors are either superficial or intraabdominal.
  • These tumors are associated with a high recurrence rates, even if their microscopic characters indicate a benign disease; their biologic behavior often indicates rather a "malignant" disease, which can cause even the death.
  • Intraabdominal desmoid tumors can engulf surrounding viscera and vessels, thereby greatly complicating their surgical treatment.
  • [MeSH-major] Abdominal Neoplasms / pathology. Abdominal Neoplasms / therapy. Fibromatosis, Aggressive / pathology. Fibromatosis, Aggressive / therapy
  • [MeSH-minor] Algorithms. Diagnosis, Differential. Diagnostic Imaging. Genetic Testing. Humans. Medical History Taking

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  • (PMID = 17719772.001).
  • [ISSN] 0960-7404
  • [Journal-full-title] Surgical oncology
  • [ISO-abbreviation] Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 86
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39. Kourda N, Ben Slama S, Mrabet N, Sayari S, Zouache A, Ben Jilani SB, Zermani R: [Abdominal desmoid tumor: pathologic and therapeutic concepts]. Tunis Med; 2008 Oct;86(10):916-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Abdominal desmoid tumor: pathologic and therapeutic concepts].
  • [Transliterated title] Tumeur desmoide abdominale: concepts histopathologiques et therapeutiques.
  • BACKGROUND: Abdominal desmoid tumors arise in young adults between 20 and 40 years.
  • METHODS: From 1990 to 2004, three cases of abdominal desmoid tumors were diagnosed in the Pathologic laboratory of the Charles Nicole Hospital of Tunis.
  • CONCLUSION: Abdominal desmoid tumors are locally aggressive but never give metastasis.
  • [MeSH-major] Abdominal Neoplasms / pathology. Abdominal Neoplasms / therapy. Fibromatosis, Aggressive / pathology. Fibromatosis, Aggressive / therapy

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  • (PMID = 19472812.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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40. Ko SF, Lin JW, Ng SH, Huang CC, Wan YL, Huang HY, Sheen-Chen SM: Spontaneous isolated mesenteric fibromatosis: sonographic and computed tomographic findings with pathologic correlation. Ultrasound Med Biol; 2006 Aug;32(8):1141-9
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  • [Title] Spontaneous isolated mesenteric fibromatosis: sonographic and computed tomographic findings with pathologic correlation.
  • Eight cases of spontaneous isolated mesenteric fibromatosis (SIMF) were retrospectively reviewed.
  • Clinical presentations included palpable abdominal mass (n = 6), abdominal pain (n = 4), gastrointestinal bleeding (n = 2) and acute abdomen (n = 1).
  • On sonography and computed tomography (CT), eight SIMFs (size range 3 to 24 cm, mean 14.8 cm) were categorized into four morphologic patterns: well-defined inhomogeneous, well-defined homogeneous, well-defined cystic or infiltrative mesenteric mass patterns.
  • Well-defined inhomogeneous SIMF (n = 3) was correlated with the histopathologic finding of bundles of fibroblasts with unevenly intermingled hyaline and/or myxoid degeneration areas, whereas well-defined homogeneous SIMF (n = 2) showed scarce degenerative changes.
  • One SIMF presented as an infiltrative mesenteric mass and the patient died 10 months after diagnosis.
  • Both cases of cystic SIMFs showed tumor recurrences and one patient died after 84 months.
  • The other five patients were cured by radical tumor resection.
  • In summary, sonography, similar to CT, is also useful for evaluating SIMF with protean morphologic features, ascribing to the underlying histopathologic changes with varied degrees of hyaline, myxoid or cystic degenerations.
  • [MeSH-major] Fibromatosis, Abdominal / ultrasonography. Mesentery / ultrasonography

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  • (PMID = 16875948.001).
  • [ISSN] 0301-5629
  • [Journal-full-title] Ultrasound in medicine & biology
  • [ISO-abbreviation] Ultrasound Med Biol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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41. Rampone B, Pedrazzani C, Marrelli D, Pinto E, Roviello F: Updates on abdominal desmoid tumors. World J Gastroenterol; 2007 Dec 7;13(45):5985-8
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  • [Title] Updates on abdominal desmoid tumors.
  • Desmoid tumor is a monoclonal, fibroblastic proliferation arising in musculoaponeurotic structures.
  • Abdominal desmoid occurs sporadically, in association with some familial syndromes and often represents a clinical dilemma for surgeons.
  • The enigmatic biology and anatomical location of abdominal desmoids make treatment recommendations difficult.
  • [MeSH-major] Fibromatosis, Abdominal / therapy. Neoplasm Recurrence, Local

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  • (PMID = 18023087.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 50
  • [Other-IDs] NLM/ PMC4250878
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42. Tanaka K, Yoshikawa R, Yanagi H, Gega M, Fujiwara Y, Hashimoto-Tamaoki T, Hirota S, Tsujimura T, Tomita N: Regression of sporadic intra-abdominal desmoid tumour following administration of non-steroidal anti-inflammatory drug. World J Surg Oncol; 2008;6:17
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regression of sporadic intra-abdominal desmoid tumour following administration of non-steroidal anti-inflammatory drug.
  • BACKGROUND: Desmoid tumours or fibromatoses are rare entities characterized by the benign proliferation of fibroblasts, which can be life-threatening due to their locally aggressive properties.
  • Surgery is widely accepted as the first line of treatment for extra-abdominal desmoids; however, it is not recommended for intra-abdominal desmoids because of the high-risk of recurrence and difficulties with the operation.
  • Here, we report on a patient with sporadic intra-abdominal desmoid tumours, who showed partial response following the intake of non-steroidal anti-inflammatory drugs.
  • Computed tomography showed an abnormal multilocular soft-tissue mass (95 x 70 mm) in the right pelvis, which was revealed by biopsy to be a desmoid tumour.
  • Immunohistochemical analysis showed that the tumour cells expressed vimentin, but not smooth-muscle actin, CD34, or desmin.
  • Two years after the commencement of non-steroidal anti-inflammatory drug administration, computed tomography showed a decrease in tumour size (63 x 49 mm), and the disappearance of intratumoural septa.
  • CONCLUSION: Our case report suggests that non-steroidal anti-inflammatory drug treatment should be taken into consideration for use as first-line treatment in patients with sporadic intra-abdominal desmoid tumours.
  • [MeSH-major] Abdominal Neoplasms / drug therapy. Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Fibromatosis, Abdominal / drug therapy. Fibromatosis, Aggressive / drug therapy

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  • (PMID = 18257933.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal
  • [Other-IDs] NLM/ PMC2270274
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43. Lund H, Ekvall BF: [Mesenteric fibromatosis]. Ugeskr Laeger; 2009 Nov 23;171(48):3539-40
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  • [Title] [Mesenteric fibromatosis].
  • [Transliterated title] Mesenteriel fibromatose.
  • Mesenterial fibromatosis is a benign proliferating neoplasia that originates from the mesenterium or retroperitoneum.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Intestine, Small / pathology. Mesentery. Neoplasm Recurrence, Local

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  • (PMID = 19944057.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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44. Lahat G, Nachmany I, Itzkowitz E, Abu-Abeid S, Barazovsky E, Merimsky O, Klauzner J: Surgery for sporadic abdominal desmoid tumor: is low/no recurrence an achievable goal? Isr Med Assoc J; 2009 Jul;11(7):398-402
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  • [Title] Surgery for sporadic abdominal desmoid tumor: is low/no recurrence an achievable goal?
  • BACKGROUND: Sporadic abdominal desmoid tumors are rare and data on these tumors as a distinct disease entity are lacking.
  • Previous abdominal surgery, trauma, pregnancy and estrogen intake are considered risk factors.
  • OBJECTIVES: To evaluate outcomes of surgery for this rare disease.
  • METHODS: Since 1995, 16 patients with pathologically confirmed desmoid tumor were operated on in our center.
  • All patients presented with an isolated mass; 7 (50%) originated in the abdominal wall, 6 (37.5%) were retroperitoneal and 3 were (18.8%) mesenteric.
  • CONCLUSIONS: The perception of sporadic abdominal desmoids as tumors with a high recurrence rate (20-70%) is probably incorrect.
  • [MeSH-major] Abdominal Neoplasms / surgery. Fibromatosis, Aggressive / surgery

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  • (PMID = 19911489.001).
  • [ISSN] 1565-1088
  • [Journal-full-title] The Israel Medical Association journal : IMAJ
  • [ISO-abbreviation] Isr. Med. Assoc. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Israel
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45. Collins D, Myers E, Kavanagh D, Lennon G, McDermott E: Mesenteric desmoid tumor causing ureteric obstruction. Int J Urol; 2008 Mar;15(3):261-2
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  • [Title] Mesenteric desmoid tumor causing ureteric obstruction.
  • Desmoid tumors are rare, accounting for just 0.03% of all neoplasms and less than 3% of all soft tissue tumors.
  • We describe the case of a 16-year-old female who presented with hydronephroureter secondary to an intra-abdominal desmoid tumor.
  • This case report draws the attention of urologists to the diagnostic dilemma and therapeutic challenges associated with an intra-abdominal mass causing ureteral obstruction especially in young patients.
  • [MeSH-major] Fibromatosis, Aggressive / complications. Mesentery. Peritoneal Neoplasms / complications. Ureteral Obstruction / etiology

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  • (PMID = 18304225.001).
  • [ISSN] 1442-2042
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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46. Tan CH, Pua U, Liau KH, Lee HY: Mesenteric desmoid tumour masquerading as a fat-containing cystic mass. Br J Radiol; 2010 Oct;83(994):e200-3
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  • [Title] Mesenteric desmoid tumour masquerading as a fat-containing cystic mass.
  • Mesenteric desmoid tumour (MDT) is an uncommon neoplasm that typically presents as a solid soft-tissue mass on cross-sectional imaging.
  • [MeSH-major] Cysts / radiography. Fibromatosis, Abdominal / radiography. Mesenteric Cyst / radiography
  • [MeSH-minor] Abdominal Pain / etiology. Diagnosis, Differential. Female. Humans. Middle Aged. Tomography, X-Ray Computed. Vomiting / etiology

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  • (PMID = 20846976.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3473748
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47. Pho LN, Coffin CM, Burt RW: Abdominal desmoid in familial adenomatous polyposis presenting as a pancreatic cystic lesion. Fam Cancer; 2005;4(2):135-8
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  • [Title] Abdominal desmoid in familial adenomatous polyposis presenting as a pancreatic cystic lesion.
  • An abdominal CT scan detected a cystic pancreatic lesion of unknown etiology.
  • Histopathological examination of the resected specimen showed a benign pancreatic cyst and fibrous plaque with desmoid fibromatosis adherent to the surface of the pancreas, serosa of the stomach, and colon.
  • The fibrous plaque was histologically identical to the fibrous mesenteric plaque known to occur in FAP and associated mesenteric fibromatosis.
  • We present pathologic evidence that the pancreatic cyst formation was induced by FAP-associated desmoid invasion.
  • Desmoid growth should be considered in the differential diagnosis of a pancreatic cystic mass lesion in patients with FAP or its Gardner syndrome variant.
  • This case report provides the first pathologic evidence for benign epithelial cyst formation in the pancreas caused by fibromatosis invasion of that organ as a part of FAP.
  • [MeSH-major] Adenomatous Polyposis Coli / complications. Adenomatous Polyposis Coli / pathology. Fibromatosis, Aggressive / complications. Fibromatosis, Aggressive / diagnosis. Pancreatic Cyst / diagnosis. Pancreatic Cyst / etiology
  • [MeSH-minor] Adolescent. Chest Pain. Diagnosis, Differential. Humans. Male. Weight Loss

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  • (PMID = 15951964.001).
  • [ISSN] 1389-9600
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P01 CA 73992; United States / NCI NIH HHS / CA / P30 CA 42014; United States / NCI NIH HHS / CA / R01 CA 40641
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Netherlands
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48. Efstratiadis G, Garyfallos A, Tsiaousis G, Jiavazis I, Deretzi G, Leontsini M, Venizelos I, Memmos D: Necrotic vasculitis in a patient with abdominal fibromatosis and Guillain-Barré syndrome. Ren Fail; 2006;28(8):743-7
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  • [Title] Necrotic vasculitis in a patient with abdominal fibromatosis and Guillain-Barré syndrome.
  • Tomographic investigation revealed abdominal and retroperitoneal fibromatosis.
  • [MeSH-major] Fibromatosis, Abdominal / complications. Guillain-Barre Syndrome / complications. Vasculitis / pathology
  • [MeSH-minor] Aged. Antibodies, Antineutrophil Cytoplasmic / blood. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / blood. CA-125 Antigen / blood. Cyclophosphamide / administration & dosage. Female. Humans. Kidney / pathology. Methylprednisolone / administration & dosage. Necrosis / complications. Tomography, X-Ray Computed. Ultrasonography, Interventional


49. White JA, Todd PA, Yee JL, Kalman-Bowlus A, Rodgers KS, Yang X, Wong SW, Barry P, Lerche NW: Prevalence of viremia and oral shedding of rhesus rhadinovirus and retroperitoneal fibromatosis herpesvirus in large age-structured breeding groups of rhesus macaques (Macaca mulatta). Comp Med; 2009 Aug;59(4):383-90
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  • [Title] Prevalence of viremia and oral shedding of rhesus rhadinovirus and retroperitoneal fibromatosis herpesvirus in large age-structured breeding groups of rhesus macaques (Macaca mulatta).
  • We performed a cross-sectional study to estimate the prevalence of 2 gamma-2-herpesviruses, rhesus rhadinovirus (RRV) and retroperitoneal fibromatosis herpesvirus (RFHV), in breeding colonies of rhesus macaques.

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  • (PMID = 19712580.001).
  • [ISSN] 1532-0820
  • [Journal-full-title] Comparative medicine
  • [ISO-abbreviation] Comp. Med.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / RR00169; United States / NCRR NIH HHS / RR / P51 RR000163; United States / NCRR NIH HHS / RR / RR00163; United States / NCRR NIH HHS / RR / P51 RR000169; United States / NCRR NIH HHS / RR / K01 RR000163; United States / NCI NIH HHS / CA / R01 CA075922; United States / NCI NIH HHS / CA / CA75922
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers
  • [Other-IDs] NLM/ PMC2779215
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50. Kreuzberg B, Koudelova J, Ferda J, Treska V, Spidlen V, Mukensnabl P: Diagnostic problems of abdominal desmoid tumors in various locations. Eur J Radiol; 2007 May;62(2):180-5
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  • [Title] Diagnostic problems of abdominal desmoid tumors in various locations.
  • BACKGROUND: Abdominal desmoid tumor is one of the forms of deep (musculoaponeurotic) fibromatosis.
  • It occurs more often as a desmoid tumor in the abdominal wall, less often in various intra-abdominal locations.
  • In this work, we performed retrospective study concerning diagnostic problems of this disease with the use of imaging techniques.
  • RESULTS: The findings were typical only in the case with the lesion located in the abdominal wall, three described cases of the intra-abdominal desmoid provided a broad range of differentially diagnostic possibilities (metastases, GIT tumors, lymphomas, etc.).
  • In particular, the findings in infiltrative processes in intra-abdominal location and retroperitoneal involvement were less typical.
  • CONCLUSION: The possibility of the occurrence of intra-abdominal desmoid tumor must be considered particularly in younger individuals with rapidly growing tumorous process, which does not immediately arise from the surrounding organs (digestive tract, internal genitalia, etc.
  • ), and is located in the abdominal wall or in the abdominal cavity.
  • [MeSH-major] Fibromatosis, Abdominal / diagnosis. Fibromatosis, Aggressive / diagnosis
  • [MeSH-minor] Abdominal Cavity / pathology. Abdominal Wall / pathology. Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Tomography, X-Ray Computed

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  • (PMID = 17321093.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
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51. Pérez García FJ, Pinto Blazquez J, Rodríguez Martínez JJ, Gutiérrez García R, Jorge Barreiro JI, Velasco Alonso J: [Mesenteric desmoid tumor mimicking a testicular cancer recurrence]. Arch Esp Urol; 2007 Jul-Aug;60(6):703-6
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  • [Title] [Mesenteric desmoid tumor mimicking a testicular cancer recurrence].
  • [Transliterated title] Tumor desmoide mesentérico simulando una recidiva de cáncer testicular.
  • OBJECTIVE: Report of one case of desmoid tumor in a patient who had been treated of a testicular seminoma 26 months before, with excision of a retroperitoneal mass and chemotherapy.
  • On followup he presented with a mesenteric abdominal mass which was clinically labeleled as a recurrence of the seminoma.
  • RESULTS: Histologically it was reported as a mesenteric desmoid tumor.
  • Differential diagnosis with gastrointestinal stromal tumor was performed with immunohistochemical studies.
  • CONCLUSIONS: Desmoid tumor is rare.
  • There are few cases reported in patients with history of previous testicular tumor.
  • It should be included in the differential diagnosis of testicular tumor recurrences.
  • [MeSH-major] Fibromatosis, Aggressive / diagnosis. Mesentery. Peritoneal Neoplasms / diagnosis. Seminoma / diagnosis. Testicular Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 17847750.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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52. Agaimy A, Wünsch PH: Distribution of neural cell adhesion molecule (NCAM/CD56) in gastrointestinal stromal tumours and their intra-abdominal mesenchymal mimics. J Clin Pathol; 2008 Apr;61(4):499-503
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  • [Title] Distribution of neural cell adhesion molecule (NCAM/CD56) in gastrointestinal stromal tumours and their intra-abdominal mesenchymal mimics.
  • METHODS: 275 histologically and immunohistochemically well characterised primary and metastatic intra-abdominal mesenchymal lesions were analysed by conventional immunohistochemistry, with emphasis on GIST and GI smooth muscle neoplasms.
  • Mesenteric fibromatoses, angiosarcoma/Kaposi sarcoma, reactive tumefactive fibrogenic lesions and 12/13 primary anorectal and oesophageal melanomas were negative.
  • CD56 plays a limited role in the differential diagnosis of GIST.
  • [MeSH-major] Antigens, CD56 / metabolism. Biomarkers, Tumor / metabolism. Gastrointestinal Stromal Tumors / metabolism. Neoplasm Proteins / metabolism
  • [MeSH-minor] Diagnosis, Differential. Fibrosarcoma / diagnosis. Fibrosarcoma / metabolism. Humans. Melanoma / diagnosis. Melanoma / metabolism. Melanoma / secondary. Neoplasms, Muscle Tissue / diagnosis. Neoplasms, Muscle Tissue / metabolism. Nerve Sheath Neoplasms / metabolism. Prognosis

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  • (PMID = 17923471.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD56; 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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53. Viriyaroj V, Yingsakmongkol N, Pasukdee P, Rermluk N: A large abdominal desmoid tumor associated with pregnancy. J Med Assoc Thai; 2009 Jun;92 Suppl 3:S72-5
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  • [Title] A large abdominal desmoid tumor associated with pregnancy.
  • Desmoid tumors are rare, benign tumors with locally aggressive behavior which originate from fascial or musculoaponeurotic structure.
  • The etiology of desmoid tumors are uncertain but may be related to operation, trauma or hormonal factors.
  • The authors report a 17-year old woman, gravida 1, para 1 with a mass at her lower abdominal wall during the fifth month of gestation.
  • She was biopsied during delivery in another hospital but was not given a definite diagnosis.
  • The tumor measured 28 x 21 x 18 centimeters in size and 4,900 g in weight.
  • Complete surgical excision was performed The pathological report was desmoid tumor (aggressive fibromatosis).
  • She had no post-operative complication and no recurrent tumor in the 8 months after operation.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Fibromatosis, Aggressive / diagnosis. Pregnancy Complications

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  • (PMID = 19702071.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
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54. Jalini L, Hemming D, Bhattacharya V: Intraabdominal desmoid tumour presenting with perforation. Surgeon; 2006 Apr;4(2):114-6
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  • [Title] Intraabdominal desmoid tumour presenting with perforation.
  • We present a rare case of a desmoid tumour presenting with perforation of the small bowel.
  • Although desmoid is classified pathologically as a benign tumour, its infiltrative nature leads to a locally aggressive mass, which can invade surrounding structures and organs making surgical resection difficult.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Intestinal Perforation / etiology. Intestine, Small. Mesentery. Peritoneal Neoplasms / pathology

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  • (PMID = 16623170.001).
  • [ISSN] 1479-666X
  • [Journal-full-title] The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
  • [ISO-abbreviation] Surgeon
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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55. Bölke E, Krasniqi H, Lammering G, Engers R, Matuschek C, Gripp S, Gerber PA, Fischer G, Peiper M, Shaikh S, Budach W, Orth K: Chest wall and intrathoracic desmoid tumors: surgical experience and review of the literature. Eur J Med Res; 2009 Jun 18;14(6):240-3
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  • [Title] Chest wall and intrathoracic desmoid tumors: surgical experience and review of the literature.
  • Desmoid tumors are fibroblastic/myofibroblastic neoplasms, which originate from musculo-aponeurotic structures and are classified as deep fibromatoses.
  • Despite their benign histologic appearance and lack of metastatic potential, desmoid tumors may cause aggres?sive local infiltrations and compression of surrounding structures.
  • Radical tumor resection with free margins remains the first therapy of choice.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Fibromatosis, Aggressive / pathology. Thoracic Neoplasms / pathology. Thoracic Wall / pathology

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  • (PMID = 19541583.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 31
  • [Other-IDs] NLM/ PMC3352015
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56. Burnside KL, Ryan JT, Bielefeldt-Ohmann H, Gregory Bruce A, Thouless ME, Tsai CC, Rose TM: RFHVMn ORF73 is structurally related to the KSHV ORF73 latency-associated nuclear antigen (LANA) and is expressed in retroperitoneal fibromatosis (RF) tumor cells. Virology; 2006 Oct 10;354(1):103-15
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  • [Title] RFHVMn ORF73 is structurally related to the KSHV ORF73 latency-associated nuclear antigen (LANA) and is expressed in retroperitoneal fibromatosis (RF) tumor cells.
  • Retroperitoneal fibromatosis herpesvirus (RFHV), the macaque homolog of the human rhadinovirus, Kaposi's sarcoma-associated herpesvirus (KSHV), was first identified in retroperitoneal fibromatosis (RF) tumor lesions of macaques with simian AIDS.
  • Immunohistochemical and immunofluorescence analysis revealed that RFHVMn LANA is a nuclear antigen which is highly expressed in RF spindloid tumor cells.
  • [MeSH-major] Antigens, Viral / genetics. Fibroma / virology. Nuclear Proteins / genetics. Open Reading Frames. Retroperitoneal Neoplasms / virology. Rhadinovirus / genetics
  • [MeSH-minor] Amino Acid Sequence. Animals. Antibodies, Monoclonal. Cell Nucleus / chemistry. Cloning, Molecular. DNA, Viral / chemistry. DNA, Viral / genetics. Immunohistochemistry. Macaca nemestrina. Microscopy, Fluorescence. Molecular Sequence Data. Protein Structure, Secondary. Protein Structure, Tertiary. Sequence Analysis, DNA. Sequence Homology, Amino Acid. Tumor Cells, Cultured

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  • (PMID = 16879850.001).
  • [ISSN] 0042-6822
  • [Journal-full-title] Virology
  • [ISO-abbreviation] Virology
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / DE07023; United States / NIAID NIH HHS / AI / K02 AI49275; United States / NCRR NIH HHS / RR / RR13154
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, Viral; 0 / DNA, Viral; 0 / Nuclear Proteins; 0 / latency-associated nuclear antigen
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57. Kato Y, Tsuyuki A, Kikuchi K, Kurihara N, Fujishiro Y: Mesenteric fibromatosis successfully resected with duodeno-jejunectomy and nephrectomy. Hepatogastroenterology; 2005 Nov-Dec;52(66):1730-3
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  • [Title] Mesenteric fibromatosis successfully resected with duodeno-jejunectomy and nephrectomy.
  • We report a rare case of intra-abdominal fibromatosis of the jejunal mesentery.
  • A 71-year-old man, who was incidentally diagnosed with left hydronephrosis, was found to have a tumor near the duodeno-jejunal junction.
  • The tumor appeared to invade the intestinal wall and was obstructing the left ureter.
  • The tumor was indefinite in diagnosis preoperatively.
  • The patient underwent an en-bloc excision of the tumor by a partial duodeno-jejunectomy combined with a left nephrectomy.
  • Microscopic examination of the tumor showed that non-dysplastic fibroblasts proliferating in the jejunal mesentery had infiltrated into the adjacent small intestines and ureter, resulting in a diagnosis of intra-abdominal fibromatosis.
  • This diagnosis was supported by findings of immunohistochemical analyses showing positive staining for vimentin and smooth muscle actin and negativity for keratin, CD34, C-kit and S-100.
  • To our knowledge, this is the first documented case of intra-abdominal fibromatosis of the jejunal mesentery completely resected with the operative procedure described herein.
  • In cases of a preoperatively undiagnosed retroperitoneal or mesenteric tumor that invades adjacent structures, it is important to consider intra-abdominal fibromatosis as a possible differential diagnosis.
  • [MeSH-major] Fibromatosis, Abdominal / surgery. Kidney Neoplasms / secondary. Kidney Neoplasms / surgery. Neoplasm Invasiveness / pathology. Peritoneal Neoplasms / surgery
  • [MeSH-minor] Aged. Anastomosis, Surgical. Biopsy, Needle. Duodenum / surgery. Follow-Up Studies. Humans. Hydronephrosis / diagnosis. Hydronephrosis / surgery. Immunohistochemistry. Jejunum / surgery. Magnetic Resonance Imaging / methods. Male. Mesentery / pathology. Neoplasm Staging. Nephrectomy / methods. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16334767.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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58. Giuliani A, Demoro M, Ciardi A, Scimó M, Galati F, Lonardo MT, Galati G: Mesenteric fibromatosis. Case report. J Exp Clin Cancer Res; 2007 Sep;26(3):425-8
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  • [Title] Mesenteric fibromatosis. Case report.
  • Deep fibromatosis is a rare locally aggressive but not metastasizing proliferation.
  • Intra-abdominal fibromatosis (IAF) occurs either in association with Gardner's syndrome or as a sporadic event and presents in most cases differential diagnostic problems with myofibroblastic or fibroblastic tumors, characterized by a more aggressive biological behaviour such as gastrointestinal stromal tumors (GISTs).
  • In absence of loco-regional and/or distant metastasis differential diagnosis may be difficult and represents a topical issue, since it influences treatment choice.
  • We describe the case of a patient with sporadic IAF in which the tumor locally involved the mesentery and presented no loco-regional and distant spread.
  • Definitive diagnosis was made, postoperatively, on the basis of immunohistochemical findings.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Fibroma / diagnosis. Mesentery
  • [MeSH-minor] Diagnosis, Differential. Gardner Syndrome / pathology. Humans. Male. Middle Aged

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  • (PMID = 17987807.001).
  • [ISSN] 0392-9078
  • [Journal-full-title] Journal of experimental & clinical cancer research : CR
  • [ISO-abbreviation] J. Exp. Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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59. Philipp-Staheli J, Marquardt T, Thouless ME, Bruce AG, Grant RF, Tsai CC, Rose TM: Genetic variability of the envelope gene of Type D simian retrovirus-2 (SRV-2) subtypes associated with SAIDS-related retroperitoneal fibromatosis in different macaque species. Virol J; 2006 Mar 06;3:11
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  • [Title] Genetic variability of the envelope gene of Type D simian retrovirus-2 (SRV-2) subtypes associated with SAIDS-related retroperitoneal fibromatosis in different macaque species.
  • SAIDS is often accompanied by retroperitoneal fibromatosis (RF), an aggressive fibroproliferative disorder reminiscent of Kaposi's sarcoma in patients with HIV-induced AIDS.

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  • (PMID = 16515713.001).
  • [ISSN] 1743-422X
  • [Journal-full-title] Virology journal
  • [ISO-abbreviation] Virol. J.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / RR13154; United States / NCRR NIH HHS / RR / P51 RR000166; United States / NIAID NIH HHS / AI / K02 AI49275; United States / NCRR NIH HHS / RR / R01 RR013154; United States / NIAID NIH HHS / AI / K02 AI049275; United States / NCRR NIH HHS / RR / RR00166
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Viral Envelope Proteins
  • [Other-IDs] NLM/ PMC1450265
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60. Koh PK, Loi C, Cao X, Cheah PY, Ho KS, Ooi BS, Tang CL, Eu KW: Mesenteric desmoid tumors in Singapore familial adenomatous polyposis patients: clinical course and genetic profile in a predominantly Chinese population. Dis Colon Rectum; 2007 Jan;50(1):75-82
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  • [Title] Mesenteric desmoid tumors in Singapore familial adenomatous polyposis patients: clinical course and genetic profile in a predominantly Chinese population.
  • PURPOSE: This study examined the mutational profile of the adenomatous polyposis coli gene in relation to the development of desmoid tumors in familial adenomatous polyposis patients from a predominantly Chinese population.
  • Identification of specific adenomatous polyposis coli gene mutation was performed and clinical course of associated desmoid disease obtained from case records and a computerized database.
  • The clinical course of desmoid tumors can be divided into stable (n=11), variable (n=3), progressive (n=6), and aggressive growth (n=3).
  • Only 3 (13 percent) patients with aggressive tumor growth required chemotherapy.
  • The most common complications related to the mesenteric desmoids were intestinal obstruction (21.7 percent), ureteric obstruction (17.4 percent), and encasement of superior mesenteric vessels (13 percent).
  • CONCLUSION: The clinical course of desmoids in an individual familial adenomatous polyposis patient remains unpredictable and no reliable genetic marker is available for prognostication in desmoid disease.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Fibromatosis, Abdominal / genetics

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  • (PMID = 17082890.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Codon
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61. Carlson JW, Fletcher CD: Immunohistochemistry for beta-catenin in the differential diagnosis of spindle cell lesions: analysis of a series and review of the literature. Histopathology; 2007 Oct;51(4):509-14
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  • [Title] Immunohistochemistry for beta-catenin in the differential diagnosis of spindle cell lesions: analysis of a series and review of the literature.
  • AIMS: Nuclear staining for beta-catenin by immunohistochemistry is being used increasingly to diagnose desmoid tumours (deep fibromatoses), especially where the differential diagnosis includes other abdominal spindle cell neoplasms.
  • This study aimed to define the prevalence of beta-catenin positivity in desmoid tumours and other morphologically similar spindle cell neoplasms.
  • Nuclear immunopositivity was detected in 80% of cases of sporadic desmoid fibromatosis (24/30) and in 67% of tumours in patients with familial adenomatous polyposis (8/12).
  • Nuclear positivity was also present in 14/25 superficial fibromatoses (56%), 3/10 low-grade myofibroblastic sarcomas (30%), 5/23 solitary fibrous tumours (22%), 1/5 infantile fibrosarcomas (20%), 1/18 desmoplastic fibroblastomas (6%) and 1/21 gastrointestinal stromal tumours (5%).
  • No nuclear immunoreactivity was present in neurofibromas (0/26), schwannomas (0/25), nodular fasciitis (0/19), leiomyosarcomas (0/16), inflammatory myofibroblastic tumours (0/12), fibromas of tendon sheath (0/9), lipofibromatoses (0/5), Gardner fibromas (0/4), calcifying aponeurotic fibromas (0/4) or fibromatosis colli (0/1).
  • CONCLUSION: Nuclear staining for beta-catenin is supportive, but not definitive, of the diagnosis of desmoid fibromatosis.
  • No significant difference in immunoreactivity was observed between sporadic and familial desmoid fibromatoses. beta-Catenin negativity does not preclude the diagnosis of fibromatosis.
  • [MeSH-major] Abdominal Neoplasms / chemistry. Sarcoma / chemistry. beta Catenin / analysis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Cell Nucleus / chemistry. Cell Nucleus / pathology. Diagnosis, Differential. Fibromatosis, Abdominal / diagnosis. Fibromatosis, Abdominal / pathology. Humans. Immunohistochemistry

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  • (PMID = 17711447.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / beta Catenin
  • [Number-of-references] 19
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62. Leithner A, Gapp M, Radl R, Pascher A, Krippl P, Leithner K, Windhager R, Beham A: Immunohistochemical analysis of desmoid tumours. J Clin Pathol; 2005 Nov;58(11):1152-6
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  • [Title] Immunohistochemical analysis of desmoid tumours.
  • BACKGROUND/AIMS: Although the standard treatment for desmoid tumours is complete surgical resection with wide margins, the optimal adjuvant treatment for recurrent or inoperable disease is unclear, often being based on sporadic immunohistochemical reports with a low number of cases.
  • METHODS: One hundred and sixteen tissue samples from 80 patients (49 female, 31 male; mean age, 34 years; range, 0-83) with desmoid tumours (46 extra-abdominal, 21 abdominal, 13 intra-abdominal) were tested for oestrogen receptors alpha and beta, progesterone and androgen receptors, and somatostatin, in addition to HER2, cathepsin D, Ki-67, and c-KIT by immunohistochemistry.
  • Positive staining for the androgen receptor was found in six extra-abdominal cases.
  • Staining for oestrogen receptor beta was positive in four extra-abdominal, two abdominal, and one intra-abdominal case.
  • Staining for somatostatin was positive in six extra-abdominal, two abdominal, and one intra-abdominal case, and staining for cathepsin D was positive in all cases.
  • Positive staining for Ki-67 was found in 14 extra-abdominal, three abdominal, and three intra-abdominal cases.
  • C-KIT was detectable in one abdominal case only.
  • CONCLUSIONS: The data from this immunohistochemical study show that the published effects of antioestrogens and imatinib mesylate in the treatment of aggressive fibromatoses may not be attributable to oestrogen receptor alpha or c-KIT expression.
  • [MeSH-major] Biomarkers, Tumor / analysis. Fibromatosis, Aggressive / metabolism. Soft Tissue Neoplasms / chemistry
  • [MeSH-minor] Abdominal Neoplasms / chemistry. Abdominal Neoplasms / drug therapy. Abdominal Neoplasms / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Cathepsin D / analysis. Chemotherapy, Adjuvant. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Ki-67 Antigen / analysis. Male. Middle Aged. Neoplasm Proteins / analysis. Proto-Oncogene Proteins c-kit / analysis. Receptors, Androgen / analysis. Receptors, Estrogen / analysis. Receptors, Progesterone / analysis. Somatostatin / analysis

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  • (PMID = 16254103.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Neoplasm Proteins; 0 / Receptors, Androgen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 51110-01-1 / Somatostatin; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 3.4.23.5 / Cathepsin D
  • [Other-IDs] NLM/ PMC1770757
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63. Durno C, Monga N, Bapat B, Berk T, Cohen Z, Gallinger S: Does early colectomy increase desmoid risk in familial adenomatous polyposis? Clin Gastroenterol Hepatol; 2007 Oct;5(10):1190-4
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  • [Title] Does early colectomy increase desmoid risk in familial adenomatous polyposis?
  • BACKGROUND & AIMS: Desmoid tumors are non-metastasizing fibromatoses that occur in 10%-20% of subjects with familial adenomatous polyposis (FAP).
  • Intra-abdominal desmoid tumors are a major cause of mortality in FAP.
  • FAP-associated desmoid tumors are linked to trauma, particularly abdominal surgery, family history of desmoids, hormonal factors, and the location of the APC mutation.
  • The aim of this study was to determine whether colectomy earlier in life is a risk factor for the development of desmoid tumors.
  • METHODS: An analysis was made of the association between development of desmoid and age at colectomy, family history of desmoids, gender, and APC mutation in FAP patients in the Registry (1980-2005) at Mount Sinai Hospital, Toronto, Ontario, Canada.
  • Desmoid prevalence was 14% (n = 121).
  • Female patients who had an early colectomy were more than 2 times more likely to develop a desmoid, compared with women who had a colectomy at >18 years (P = .01).
  • Early colectomy did not increase risk of developing a desmoid in male patients (P = .42).
  • Patients with a mutation after codon 1399 were found to have 4 times greater chance of developing a desmoid.
  • Female patients who had an early colectomy are at significantly greater risk of developing a desmoid compared with female patients who had a colectomy in adulthood.
  • [MeSH-major] Abdominal Neoplasms / etiology. Adenomatous Polyposis Coli / surgery. Colectomy / adverse effects. Fibromatosis, Aggressive / etiology

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  • (PMID = 17916546.001).
  • [ISSN] 1542-7714
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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64. Bruce AG, Bakke AM, Bielefeldt-Ohmann H, Ryan JT, Thouless ME, Tsai CC, Rose TM: High levels of retroperitoneal fibromatosis (RF)-associated herpesvirus in RF lesions in macaques are associated with ORF73 LANA expression in spindleoid tumour cells. J Gen Virol; 2006 Dec;87(Pt 12):3529-38
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  • [Title] High levels of retroperitoneal fibromatosis (RF)-associated herpesvirus in RF lesions in macaques are associated with ORF73 LANA expression in spindleoid tumour cells.
  • In macaques, the RV1 lineage is represented by retroperitoneal fibromatosis (RF) herpesvirus (RFHV), the homologue of KSHV, whilst the RV2 lineage is represented by rhesus rhadinovirus (RRV), a more distantly related virus.
  • The RV1 loads were 220- to 4300-fold higher in RF tumours than in spleen, showing a strong tumour association (mean loads of 1 800 000 vs 2900 copies per 10(6) cells in tumours and spleen, respectively).
  • Immunostaining with antibodies reactive against RFHV ORF73 latency-associated nuclear antigen (LANA) showed intense nuclear staining of the spindleoid RF tumour cells.
  • Correlation of viral load and the number of LANA-positive cells indicated that RF tumour cells contained multiple copies of the RFHV genome per cell.
  • [MeSH-major] Antigens, Viral / biosynthesis. DNA, Viral / analysis. Herpesviridae Infections / virology. Nuclear Proteins / biosynthesis. Retroperitoneal Neoplasms / virology. Rhadinovirus / physiology. Simian Acquired Immunodeficiency Syndrome / complications. Tumor Virus Infections / virology
  • [MeSH-minor] Animals. Disease Models, Animal. Immunohistochemistry. Macaca mulatta. Macaca nemestrina. Polymerase Chain Reaction / methods. Spleen / virology. Statistics as Topic

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  • (PMID = 17098967.001).
  • [ISSN] 0022-1317
  • [Journal-full-title] The Journal of general virology
  • [ISO-abbreviation] J. Gen. Virol.
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / K02 AI49275; United States / NCRR NIH HHS / RR / RR00166; United States / NCRR NIH HHS / RR / RR13154
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Viral; 0 / DNA, Viral; 0 / Nuclear Proteins; 0 / latency-associated nuclear antigen
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65. Ferenc T, Stalińska L, Turant M, Sygut J, Tosik D, Dziki A, Kulig A: Analysis of TGF-beta protein expression in aggressive fibromatosis (desmoid tumor). Pol J Pathol; 2006;57(2):77-81
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  • [Title] Analysis of TGF-beta protein expression in aggressive fibromatosis (desmoid tumor).
  • Aggressive fibromatosis, usually termed desmoid tumor, develops from muscle connective tissue, fasciae and aponeuroses.
  • Aggressive fibromatosis located in various parts of the body demonstrates differentiated biological behavior.
  • Abnormalities in TGF-beta expression are very common in many disease processes, including neoplasms.
  • Immunohistochemical analysis employing a monoclonal antibody against TGF-beta was performed on archival material, consisting of 38 cases of aggressive fibromatosis, among which 23 represented abdominal, 11 extra-abdominal and 4 intra-abdominal localizations.
  • The average percentage of cells positively stained for TGF-beta protein was 40.2% in the group of extra-abdominal, 58.5% in the group of abdominal and 72.8% in the group of intra-abdominal localizations.
  • There were significant differences observed between the analyzed groups of desmoid tumor (p<0.05).
  • A positive cytoplasmic reaction for TGF-beta was noted in 65.8% (25/38) of the aggressive fibromatoses.
  • Overexpression of TGF-beta protein was noted in 39.5% (15/38) of the aggressive fibromatoses.
  • High expression noticed in desmoid fibroblasts might indicate that this protein plays a crucial role in the development of aggressive fibromatosis.
  • [MeSH-major] Abdominal Neoplasms / metabolism. Fibromatosis, Aggressive / metabolism. Transforming Growth Factor beta / metabolism
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Cell Count. Cytoplasm / metabolism. Cytoplasm / pathology. Fibroblasts / metabolism. Fibroblasts / pathology. Humans. Image Processing, Computer-Assisted. Immunoenzyme Techniques

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  • (PMID = 17019969.001).
  • [ISSN] 1233-9687
  • [Journal-full-title] Polish journal of pathology : official journal of the Polish Society of Pathologists
  • [ISO-abbreviation] Pol J Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Transforming Growth Factor beta
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66. Ferenc T, Sygut J, Kopczyński J, Mayer M, Latos-Bieleńska A, Dziki A, Kulig A: Aggressive fibromatosis (desmoid tumors): definition, occurrence, pathology, diagnostic problems, clinical behavior, genetic background. Pol J Pathol; 2006;57(1):5-15
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  • [Title] Aggressive fibromatosis (desmoid tumors): definition, occurrence, pathology, diagnostic problems, clinical behavior, genetic background.
  • Aggressive fibromatosis, usually called desmoid tumor develops from muscle connective tissue, fasciae and aponeuroses.
  • As regards the site, aggressive fibromatoses can be divided into: extra-abdominal in the area of the shoulder and pelvic girdle or chest and neck wall; abdominal in abdominal wall muscles; intra-abdominal concerning pelvis, mesentery connective tissue or retroperitoneal space.
  • Desmoid tumor is a neoplasm which rarely turns malignant and is non-metastasizing but demonstrates ability to local infiltration into tissue and is characterized by high risk of recurrence (25-65%) after surgical treatment.
  • Desmoid tumor etiology is uncertain.
  • Most sporadic cases of aggressive fibromatosis contain a somatic mutation in either the adenomatous polyposis coli (APC) or beta-catenin genes.
  • In about 10-15 per cent of patients with familial adenomatous polyposis (FAP), aggressive fibromatosis is a parenteral manifestation of this familial syndrome conditioned by APC gene mutation.
  • Abdomen injury--most frequently due to surgery is said to play an important role in the initiation of fibrous tissue proliferative process in the cases of abdominal and intra abdominal forms.
  • [MeSH-major] Fibromatosis, Aggressive. Mesoderm / pathology

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  • (PMID = 16739877.001).
  • [ISSN] 1233-9687
  • [Journal-full-title] Polish journal of pathology : official journal of the Polish Society of Pathologists
  • [ISO-abbreviation] Pol J Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Poland
  • [Number-of-references] 93
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67. Shi B, Zhu Y, Xu Z, Liu Y, Zheng B, Qi T: Aggressive fibromatosis in the urological system. Report of two adult patients and review of the literature. Urol Int; 2007;78(1):93-6
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  • [Title] Aggressive fibromatosis in the urological system. Report of two adult patients and review of the literature.
  • Aggressive fibromatoses (AF) are locally aggressive neoplasms that do not metastasize but are frequently associated with one or more recurrences and subsequent associated morbidity.
  • AF in the urological system is quite rare and has mainly been described in single case reports or as isolated cases in a large series of extra-abdominal desmoid tumors.
  • [MeSH-major] Fibromatosis, Aggressive / diagnosis. Genital Neoplasms, Male / diagnosis. Scrotum. Urinary Bladder Neoplasms / diagnosis
  • [MeSH-minor] Adult. Cystoscopy. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Tomography, X-Ray Computed. Urography. Urologic Surgical Procedures, Male / methods


68. Matono H, Oda Y, Nakamori M, Tamiya S, Yamamoto H, Yokoyama R, Saito T, Iwamoto Y, Tsuneyoshi M: Correlation between beta-catenin widespread nuclear expression and matrix metalloproteinase-7 overexpression in sporadic desmoid tumors. Hum Pathol; 2008 Dec;39(12):1802-8
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  • [Title] Correlation between beta-catenin widespread nuclear expression and matrix metalloproteinase-7 overexpression in sporadic desmoid tumors.
  • Desmoid tumors (desmoid-type fibromatoses) are locally aggressive soft tissue tumors associated with the Wnt/beta-catenin signaling pathway (APC-beta-catenin-Tcf pathway).
  • Matrix metalloproteinase-7, which is one of the target genes of the Wnt/beta-catenin signaling pathway, has been reported to play an important role in tumor progression.
  • We examined the immunohistochemical expression of beta-catenin and matrix metalloproteinase-7 in 72 samples (63 primary and 9 recurrent samples, 63 patients) of sporadic desmoid tumors without familial adenomatous polyposis, and the genetic alteration of the beta-catenin gene in 33 frozen materials (22 primary and 11 recurrent samples, 22 patients).
  • Immunohistochemically, there was a statistically significant correlation between widespread nuclear expression of beta-catenin and overexpression of matrix metalloproteinase-7 (P < .01 in extra-abdominal desmoid, Fisher test).
  • Our results suggest that the matrix metalloproteinase-7 gene may be up-regulated by mutated or continuously elevated beta-catenin protein and that the matrix metalloproteinase-7 gene may also be targeted in the Wnt/beta-catenin signaling pathway in sporadic desmoid tumors.
  • [MeSH-major] Fibromatosis, Aggressive / metabolism. Gene Expression Regulation, Neoplastic. Matrix Metalloproteinase 7 / metabolism. Soft Tissue Neoplasms / metabolism. beta Catenin / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. Cell Nucleus / metabolism. Child. Child, Preschool. Female. Humans. Infant. Male. Middle Aged. Mutation, Missense. RNA, Messenger / metabolism. RNA, Neoplasm / analysis. Reverse Transcriptase Polymerase Chain Reaction. Young Adult

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  • (PMID = 18715618.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CTNNB1 protein, human; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / beta Catenin; EC 3.4.24.23 / MMP7 protein, human; EC 3.4.24.23 / Matrix Metalloproteinase 7
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69. Orzechowska BU, Manoharan M, Sprague J, Estep RD, Axthelm MK, Wong SW: Viral interleukin-6 encoded by rhesus macaque rhadinovirus is associated with lymphoproliferative disorder (LPD). J Med Primatol; 2009 Oct;38 Suppl 1:2-7
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  • [Title] Viral interleukin-6 encoded by rhesus macaque rhadinovirus is associated with lymphoproliferative disorder (LPD).
  • BACKGROUND: Rhesus macaques (RM) co-infected with simian immunodeficiency virus (SIV) and rhesus macaque rhadinovirus (RRV) develop abnormal cellular proliferations characterized as extra-nodal lymphoma and retroperitoneal fibromatosis (RF).
  • CONCLUSIONS: Our data support the idea that vIL-6 may be critical to the development and progression of lymphoproliferative disorder in RRV/SIV-infected RM.

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  • (PMID = 19863672.001).
  • [ISSN] 1600-0684
  • [Journal-full-title] Journal of medical primatology
  • [ISO-abbreviation] J. Med. Primatol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA132638; United States / NCI NIH HHS / CA / R01 CA075922-13; United States / NCRR NIH HHS / RR / P51 RR000163; United States / NCI NIH HHS / CA / CA075922-13; United States / NCI NIH HHS / CA / R01 CA132638-03; United States / NCRR NIH HHS / RR / RR00163; United States / NCI NIH HHS / CA / CA 75922; United States / NCRR NIH HHS / RR / K01 RR000163; United States / NCI NIH HHS / CA / R01 CA075922; United States / NCI NIH HHS / CA / CA132638-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Interleukin-6
  • [Other-IDs] NLM/ NIHMS262273; NLM/ PMC3022225
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70. Westmoreland SV, Mansfield KG: Comparative pathobiology of Kaposi sarcoma-associated herpesvirus and related primate rhadinoviruses. Comp Med; 2008 Feb;58(1):31-42
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  • Recently several new species-specific rhadinoviruses of Old World primates have been described, including retroperitoneal fibromatosis herpesvirus and rhesus rhadinovirus (Cercopithecine herpesvirus 17).
  • This review examines the comparative pathobiology of KSHV, discusses the role of macaque rhadinoviruses as models of human disease, and outlines the derivation of specific pathogen-free animals.

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  • (PMID = 19793454.001).
  • [ISSN] 1532-0820
  • [Journal-full-title] Comparative medicine
  • [ISO-abbreviation] Comp. Med.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / RR00168; United States / NCRR NIH HHS / RR / RR16020; United States / NCRR NIH HHS / RR / P51 RR000168; United States / NCRR NIH HHS / RR / K26 RR000168; United States / NCRR NIH HHS / RR / U42 RR016020
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Interferon Regulatory Factor-1; 0 / Interferon Regulatory Factors; 0 / MicroRNAs; 0 / RNA, Viral; 0 / Viral Proteins; 0 / interferon regulatory factor-4
  • [Number-of-references] 93
  • [Other-IDs] NLM/ PMC2703163
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71. Bungay AW, Smith AJ, Hsieh E, Saibil FG: The association between Crohn's disease and desmoid tumors: a novel case and review of the literature. J Crohns Colitis; 2010 Jun;4(2):207-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The association between Crohn's disease and desmoid tumors: a novel case and review of the literature.
  • They occur in association with familial adenomatous polyposis (FAP), but they may also occur in the post-traumatic peri-partum or post-abdominal surgery setting, and a few present spontaneously.
  • We describe a 50 year old male not known to have Crohn's disease and without FAP who presented with multiple desmoids.
  • Investigation of post-operative diarrhea confirmed a diagnosis of Crohn's disease.
  • This is the first report of a male patient, who had never undergone prior abdominal surgery, presenting with Crohn's disease and abdominal desmoid tumors.
  • The reasons why Crohn's disease and desmoids may be associated are explored, focusing particularly on alternations in the fibrogenic cytokine TGF-β now known to be involved in the pathogenesis of both diseases.

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  • [Copyright] Copyright © 2009. Published by Elsevier B.V.
  • (PMID = 21122508.001).
  • [ISSN] 1876-4479
  • [Journal-full-title] Journal of Crohn's & colitis
  • [ISO-abbreviation] J Crohns Colitis
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Transforming Growth Factor beta
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72. Suresh CS, Ali AA: Desmoid tumor of the tongue. Med Oral Patol Oral Cir Bucal; 2008 Dec;13(12):E761-4
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  • [Title] Desmoid tumor of the tongue.
  • Desmoid tumors are rare neoplasms accounting for 0.03% of all neoplasms and have an estimated incidence of 2 to 4 per million per year.
  • World Health Organization currently refers to all of the deep types of fibromatosis as desmoid-type of fibromatoses.
  • The term "desmoid" refers to the hard, tendon-like appearance of the tumor.
  • About fifty percent of desmoid tumors arise in the abdominal region.
  • The extra-abdominal desmoid tumors present a difficult problem in recognition and management especially because of the striking discrepancy between its deceptively harmless microscopic appearance and its potential to attain a large size, to recur, and to infiltrate neighboring tissues in the manner of a fibrosarcoma.
  • Desmoid tumors are very rare in the oral cavity with less than 5% of cases constituting oral soft tissue fibromatosis.
  • A 22-year old mentally retarded female patient with desmoid tumor occurring in the tongue is presented here.
  • [MeSH-major] Fibromatosis, Aggressive / pathology. Tongue Neoplasms / pathology

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  • (PMID = 19047962.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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73. Rosato L, Mondini G, Serbelloni M, Bertone P, Orlassino R, Cossavella D: [Intra-abdominal desmoid tumors: rare but important disease]. G Chir; 2007 Jan-Feb;28(1-2):20-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intra-abdominal desmoid tumors: rare but important disease].
  • Desmoid tumors are rare benign neoplasms with high tendency to local recurrence, and they can be divided into extra- and intra-abdominal types (mesenteric fibromatosis).
  • Six patients (3 men and 3 women) affected by extra-abdominal desmoid tumors have been treated with radical excision.
  • In two patients desmoid was intra-abdominal:.
  • 1) a 55 years old man admitted for acute abdomen and submitted, in emergency, to a laparotomy with excision of a mesenteric abscess including a jejunal loop at about one meter from Treitz;.
  • 2) 52 years old man, submitted to an elective excision of a capsulated neoplasm of the little omentum, which had caused an oppressive abdominal pain.
  • In both cases the hystological diagnosis has been desmoid tumor.
  • Surgical treatment of desmoid tumors must aim at radical excision to avoid frequent recurrences (25-65%); these have stimulated the research of other kinds of treatments, since a new surgical operation itself can lead to a further recurrence.
  • Radiotherapy has been investigated with results in 79-96% of cases, antiestrogenic therapy has been used with success in 51% of patients, and high dose tamoxifen seemed to obtain a stable disease in non operable cases.
  • Conclusive results on the efficacy of these treatments have not been obtained yet, because of the rarity of the desmoid tumors even in greater Centres.
  • [MeSH-major] Fibromatosis, Abdominal / surgery. Mesentery. Peritoneal Neoplasms / surgery
  • [MeSH-minor] Abdominal Neoplasms / pathology. Abdominal Neoplasms / surgery. Aged. Female. Fibromatosis, Aggressive / surgery. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 17313728.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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74. Khan M, Bozas G, Cooke J, Wedgwood K, Maraveyas A: Mesenteric desmoid tumor developing on the site of an excised gastrointestinal stromal tumor. Rare Tumors; 2010;2(2):e33
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  • [Title] Mesenteric desmoid tumor developing on the site of an excised gastrointestinal stromal tumor.
  • We present a case of a rare and unusual occurrence of a desmoid tumor at the site of a resected gastrointestinal stromal tumor and mimicking a recurrence, with a brief discussion of the management of desmoid tumors.

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  • (PMID = 21139835.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994513
  • [Keywords] NOTNLM ; gastrointestinal stromal tumor. / mesenteric desmoid tumor
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75. de Ferro SM, Suspiro A, Fidalgo P, Lage P, Rodrigues P, Fragoso S, Vitoriano I, Baltazar C, Albuquerque C, Bettencourt A, Leitão CN: Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case. Dis Colon Rectum; 2009 Apr;52(4):742-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case.
  • MYH-associated polyposis is an inherited autosomal recessive disease, linked to biallelic germline MYH mutations, which predisposes to the development of multiple colorectal adenomas and cancer.
  • When he was 39 years old, he developed three synchronous jejunal adenocarcinomas and a mesenteric desmoid tumor.
  • Similar to patients with familial adenomatous polyposis, desmoid tumors also may be part of the clinical spectrum of MYH-associated polyposis and may prove to be a significant clinical problem in patients submitted to prophylactic colectomy.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Colorectal Neoplasms / genetics. Fibromatosis, Aggressive / genetics. Jejunal Neoplasms / genetics. Neoplasms, Multiple Primary / genetics. Peritoneal Neoplasms / genetics
  • [MeSH-minor] Adenocarcinoma / genetics. Adenoma / genetics. Adult. DNA Glycosylases / genetics. Duodenal Neoplasms / genetics. Genetic Predisposition to Disease. Germ-Line Mutation. Humans. Intestinal Neoplasms / genetics. Intestinal Obstruction / etiology. Liver Neoplasms / secondary. Male. Mesentery. Mutation. Phenotype. Syndrome


76. Rifaat MA, Abdel Gawad WS: The use of tensor fascia lata pedicled flap in reconstructing full thickness abdominal wall defects and groin defects following tumor ablation. J Egypt Natl Canc Inst; 2005 Sep;17(3):139-48
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  • [Title] The use of tensor fascia lata pedicled flap in reconstructing full thickness abdominal wall defects and groin defects following tumor ablation.
  • As a pedicled flap its reach to the lower abdomen and groin made it an attractive option for reconstructing soft tissue defects after tumor ablation.
  • Also, the adequacy of the fascia lata as a sole substitute for abdominal wall muscles has been disputable.
  • PATIENTS AND METHODS: From April 2001 to April 2004, 12 pedicled TFL flaps were used to reconstruct 5 central abdominal wall full thickness defects and 6 groin soft tissue defects following tumor resection.
  • In one case, bilateral flaps were used to reconstruct a large central abdominal wall defect.
  • From the abdominal wall defects group, all repairs were enforced primarily with a prolene mesh except for one patient who was the first in this study.
  • Patients presenting with groin defects required coverage of exposed vessels following tumor resection.
  • RESULTS: The resulting soft tissue defects in this study were due to resection of 4 abdominal wall desmoid tumors, a colonic carcinoma infiltrating the abdominal wall, 4 primary groin soft tissue sarcomas, a metastatic SCC of the leg to groin nodes, and a primary SCC of the groin.
  • Three of those cases developed in flaps reconstructing abdominal wall defects, and one case developed in a flap used to cover a groin defect.
  • Out of the 5 cases that underwent abdominal wall reconstruction, one case developed ventral hernia, in which bilateral TFL flaps were used without mesh enforcement.
  • Only one patient died of distant metastasis of a SCC of the groin skin, 8 months postoperatively and another 2 patients with abdominal desmoid tumors developed local recurrence.
  • A pedicled flap would be appropriate for lower abdominal wall defects, and is better islanded to achieve extra mobilization and allow a tension free closure, while for groin defects, simple flap transposition should be enough.
  • Nevertheless, reconstruction for full thickness abdominal wall defects by this flap is a static reconstruction.
  • [MeSH-major] Abdominal Wall / surgery. Groin / surgery. Neoplasms / surgery. Surgical Flaps
  • [MeSH-minor] Abdominal Neoplasms / surgery. Adult. Fascia Lata. Female. Humans. Male. Middle Aged. Reconstructive Surgical Procedures

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  • (PMID = 16799651.001).
  • [ISSN] 1110-0362
  • [Journal-full-title] Journal of the Egyptian National Cancer Institute
  • [ISO-abbreviation] J Egypt Natl Canc Inst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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77. Yang JL, Wang J, Zhou XY, Li XQ, Hou YY, Zhu XZ: [Clinicopathologic and genetic studies of desmoid-type fibromatosis]. Zhonghua Bing Li Xue Za Zhi; 2006 Mar;35(3):145-50
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  • [Title] [Clinicopathologic and genetic studies of desmoid-type fibromatosis].
  • OBJECTIVE: To study the clinicopathological and genetic features of desmoid-type fibromatosis, and to investigate the feasibility of detecting trisomy 8 in formalin fixed, paraffin embedded (FFPE) tissue by fluorescence in-situ hybridization (FISH).
  • Histopathologic and immunohistochemical evaluations were available in 69 cases, and ultrastructural evaluation was done in 2 cases of desmoid-type fibromatosis.
  • Clinically, there were 44 extra-abdominal tumors, 28 abdominal wall tumors and 23 intra-abdominal lesions mostly involving the mesentery.
  • Histologically, desmoid-type fibromatoses showed longitudinal fascicles of spindle fibroblasts and myofibroblasts in a predominantly collagenous background.
  • The tumor cells stained positive for vimentin, alpha-smooth muscle actin, desmin, and beta-catenin (47.8%, 33/69).
  • Ultrastructurally, most tumor cells had features of fibroblasts, including rich endoplasmic reticulum and Golgi apparatus.
  • Some tumor cells were myofibroblast-like cells exhibiting intercellular junctions, fibronexous junctions and stress fibers.
  • Trisomy 8 was detected in 6 of 20 cases of desmoid-type fibromatosis including 5 of the 8 recurrent tumors but only one of the 12 primary tumors.
  • The latter tumor also recurred three years later.
  • CONCLUSIONS: Desmoid-type fibromatosis is an intermediate (locally aggressive) tumor that occurs predominantly in young females.
  • Trisomy 8 can be detected in FFPE tissue by FISH, and its presence serves as a useful predictor of tumor recurrence and may define a subtype of desmoid-type fibromatosis with high recurrence rate.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Fibromatosis, Aggressive / pathology. Peritoneal Neoplasms / pathology. Trisomy

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  • (PMID = 16630502.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Actins; 0 / Desmin; 0 / Vimentin; 0 / beta Catenin
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78. Jain P, Shah P, Bhansali M: Unusual presentation of an uncommon abdominal pathology. Ann R Coll Surg Engl; 2010 Oct;92(7):W19-21
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  • [Title] Unusual presentation of an uncommon abdominal pathology.
  • Desmoid tumour is a non-encapsulated locally invasive tumour, originating from fibroblasts, which has ubiquitous distribution in the body.
  • A case of a 75-year-old man, presenting with high-grade fever, dull aching abdominal pain and weight loss, suspected to be due to malignancy, is reported.
  • Histological analysis revealed mesenteric fibromatosis (desmoid tumour).
  • To the best of our knowledge, this is the first case on colonic perforation secondary to desmoid tumour.
  • [MeSH-major] Colonic Neoplasms / diagnosis. Fibromatosis, Aggressive / diagnosis
  • [MeSH-minor] Abdomen, Acute / etiology. Aged. Humans. Intestinal Perforation / etiology. Intestinal Perforation / surgery. Male. Tomography, X-Ray Computed

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  • (PMID = 20825702.001).
  • [ISSN] 1478-7083
  • [Journal-full-title] Annals of the Royal College of Surgeons of England
  • [ISO-abbreviation] Ann R Coll Surg Engl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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79. Nieuwenhuis MH, Hartgrink HH, Meijer S, Menko FH, Vasen HF: [Desmoid tumour as indication of familial adenomatous polyposis]. Ned Tijdschr Geneeskd; 2010;154:A2235
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  • [Title] [Desmoid tumour as indication of familial adenomatous polyposis].
  • In two patients, a man aged 43 and a woman aged 40 years, who presented with a desmoid tumour, familial adenomatous polyposis (FAP) was diagnosed three and six years later, respectively.
  • Desmoid-type fibromatoses usually develop sporadically, but may also be an extracolonic manifestation of FAP.
  • All patients with desmoids diagnosed who are under age 60, or with desmoids located intra-abdominally or in the abdominal wall, should be referred for colonic and genetic evaluation.
  • In all further patients with a desmoid tumour, the possibility of FAP should be considered and patient data and the family history should be evaluated thoroughly.
  • [MeSH-major] Adenomatous Polyposis Coli / diagnosis. Adenomatous Polyposis Coli / pathology. Fibromatosis, Aggressive / diagnosis. Fibromatosis, Aggressive / pathology
  • [MeSH-minor] Adult. Colonic Neoplasms / diagnosis. Colonic Neoplasms / secondary. Colonic Neoplasms / surgery. Female. Genes, APC. Genetic Predisposition to Disease. Humans. Male. Mutation. Neoplasm Metastasis. Rectal Neoplasms / diagnosis. Rectal Neoplasms / secondary. Rectal Neoplasms / surgery

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  • (PMID = 20977806.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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80. Durkin AJ, Korkolis DP, Al-Saif O, Zervos EE: Full-term gestation and transvaginal delivery after wide resection of an abdominal desmoid tumor during pregnancy. J Surg Oncol; 2005 Feb 1;89(2):86-90
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  • [Title] Full-term gestation and transvaginal delivery after wide resection of an abdominal desmoid tumor during pregnancy.
  • A 29-year-old female was diagnosed with a symptomatic, extra-abdominal desmoid tumor during the first trimester of pregnancy.
  • Preoperative diagnosis was confirmed by core-needle biopsy of the lesion.
  • At 20-weeks gestation, wide local resection of the tumor with disease-free margins, as well as abdominal wall reconstruction with polytetrafluoroethylene (PTFE) mesh was successfully undertaken.
  • Histological examination of the tumor ex vivo confirmed that the lesion was a desmoid tumor consisting of spindle cells with dense infiltrating collagenous fibers.
  • This case illustrates the probable contribution of estrogens towards desmoid tumor development, the durability of abdominal wall reconstruction when subjected to the extraordinary strain of both a gravid uterus and labor, as well as the safety and efficacy of aggressive surgical therapy during pregnancy.
  • [MeSH-major] Abdominal Wall / surgery. Delivery, Obstetric. Fibromatosis, Abdominal / surgery. Pregnancy Complications, Neoplastic / surgery


81. Weiss ES, Burkart AL, Yeo CJ: Fibromatosis of the remnant pancreas after pylorus-preserving pancreaticoduodenectomy. J Gastrointest Surg; 2006 May;10(5):679-88
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  • [Title] Fibromatosis of the remnant pancreas after pylorus-preserving pancreaticoduodenectomy.
  • Intra-abdominal fibromatosis or desmoid tumors are rare forms of connective tissue cellular dysplasia characterized by proliferation of fibroblasts and abundant collagen.
  • Sporadic intra-abdominal desmoids involving the pancreas are quite rare, as only six previously reported cases exist.
  • In this report we present a seventh case of a sporadic intraabdominal desmoid involving the pancreas.
  • The patient, a 63-year-old white man, developed the desmoid tumor following a pylorus-preserving pancreaticoduodenectomy for an insulinoma.
  • Finally, we present a complete review of the six previous cases of sporadic pancreatic fibromatosis.
  • [MeSH-minor] Fibromatosis, Aggressive / pathology. Humans. Male. Middle Aged. Tomography, X-Ray Computed / methods

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  • (PMID = 16773761.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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82. Al-Otaibi ML, Turcotte RE, Hings I, Beaudet J, Isler M, Nahal A, Wong C: Low-dose chemotherapy for extra-abdominal desmoid tumor. Saudi Med J; 2008 Dec;29(12):1730-4
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  • [Title] Low-dose chemotherapy for extra-abdominal desmoid tumor.
  • OBJECTIVE: To assess the outcome of patients with extra-abdominal desmoid tumor treated with low dose chemotherapy (methotrexate and vinblastine) both for tumor response and treatment related toxicity.
  • METHODS: We retrospectively reviewed the outcome of 12 patients who underwent low dose chemotherapy for extra abdominal desmoid of different locations.
  • We evaluated the patients for their compliance, tumor response, complications of treatment, and impact of treatment on symptoms.
  • RESULTS: Disease related morbidity included pain in 7 patients, functional limitation in 7 and cosmetic defects in 3.
  • The mean tumor size was 11 cm (3-20 cm).

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  • (PMID = 19082222.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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83. Bhattacharya B, Dilworth HP, Iacobuzio-Donahue C, Ricci F, Weber K, Furlong MA, Fisher C, Montgomery E: Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions. Am J Surg Pathol; 2005 May;29(5):653-9
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  • [Title] Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions.
  • Deep fibromatoses (desmoid tumors) are clonal myofibroblastic proliferations that are prone to aggressive local recurrences but that do not metastasize.
  • Virtually all deep fibromatoses have somatic beta-catenin or adenomatous polyposis coli (APC) gene mutations leading to intranuclear accumulation of beta-catenin.
  • Since low-grade sarcomas in general lack beta-catenin and since reactive proliferations would not be expected to have it, we predicted that nuclear beta-catenin expression would be detected in deep fibromatoses but absent in other entities in the differential diagnosis.
  • We evaluated the role of beta-catenin to help differentiate distinguish deep fibromatoses from congeners.
  • Formalin-fixed, paraffin-embedded sections from 21 lesions from 20 patients with deep fibromatoses were stained with monoclonal beta-catenin antibody (Transduction Laboratories) and compared with low-grade fibromyxoid sarcoma (n=12), leiomyosarcoma (n=10), various other fibrosarcoma variants (n=13, including 3 myofibrosarcomas, 3 sclerosing epithelioid fibrosarcomas, 5 low-grade fibrosarcomas, 1 classic fibrosarcoma arising in dermatofibrosarcoma protuberans, 1 inflammatory myxohyaline tumor/myxoinflammatory fibroblastic sarcoma), myofibroma/myofibromatosis (n=12), nodular fasciitis (n=11), and scars (n=9).
  • All 21 examples of deep fibromatosis displayed nuclear beta-catenin (focal nuclear staining in one case to 90% staining).
  • All other lesions tested (n=67) lacked nuclear labeling for beta-catenin, showing only cytoplasmic accumulation. beta-Catenin immunohistochemistry separates deep fibromatosis from entities in the differential diagnosis, a finding that can be exploited for diagnosis.
  • Most fibromatoses have diffuse nuclear staining although occasional examples only focally label.
  • [MeSH-major] Cell Nucleus / pathology. Cytoskeletal Proteins / metabolism. Fibroblasts / pathology. Fibromatosis, Abdominal / pathology. Sarcoma / pathology. Trans-Activators / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Child. Cicatrix / metabolism. Cicatrix / pathology. Cytoplasm / metabolism. Cytoplasm / pathology. Diagnosis, Differential. Fasciitis / metabolism. Fasciitis / pathology. Female. Humans. Male. Middle Aged. beta Catenin

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  • (PMID = 15832090.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CTNNB1 protein, human; 0 / Cytoskeletal Proteins; 0 / Trans-Activators; 0 / beta Catenin
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84. Janitzky A, Porsch M, Daher M, Küster D, Liehr UB: [Aggressive fibromatosis (desmoid tumor) : A rare differential diagnosis of metastasis of renal cell carcinoma]. Urologe A; 2010 Jan;49(1):81-3
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  • [Title] [Aggressive fibromatosis (desmoid tumor) : A rare differential diagnosis of metastasis of renal cell carcinoma].
  • [Transliterated title] Aggressive Fibromatose (Desmoidfibromatose) : Seltene Differentialdiagnose einer Nierenzellkarzinommetastase.
  • We report the case of a 65-year-old woman with an aggressive fibromatosis of the rectus abdominis muscle suspicious for a metastasis of renal cell carcinoma after tumor nephrectomy 3 years previously.
  • Aggressive fibromatoses (desmoid tumors) are rare semimalignant tumors of the connective tissue with local infiltration and destruction of tissue.
  • Complete resection is essential to avoid tumor relapse.
  • Aggressive fibromatosis must be considered in the differential diagnosis of renal cell carcinoma metastasis.
  • [MeSH-major] Abdominal Muscles / pathology. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Fibromatosis, Abdominal / diagnosis. Kidney Neoplasms / diagnosis. Muscle Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans


85. Lee BD, Lee W, Oh SH, Min SK, Kim EC: A case report of Gardner syndrome with hereditary widespread osteomatous jaw lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Mar;107(3):e68-72
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  • Gardner syndrome (GS) is an abnormality of familial adenomatous polyposis accompanied by characteristic jaw lesions.
  • Gardner syndrome intestinal polyps have a 100% risk of undergoing malignant transformation; consequently, early identification and surgical intervention of the disease are important to prolong the life of the patient.
  • Familial adenomatous polyposis, osteomatous jaw and ocular lesions, several dental abnormalities, and an abdominal desmoid tumor are the characteristic features of this case.
  • [MeSH-minor] Cementoma / diagnosis. Diagnosis, Differential. Ethmoid Sinus. Female. Genetic Diseases, Inborn. Humans. Middle Aged. Odontoma / etiology. Orbital Neoplasms / etiology. Paranasal Sinus Neoplasms / etiology

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  • (PMID = 19157925.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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86. Umbach JL, Strelow LI, Wong SW, Cullen BR: Analysis of rhesus rhadinovirus microRNAs expressed in virus-induced tumors from infected rhesus macaques. Virology; 2010 Sep 30;405(2):592-9
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  • Using deep sequencing, we analyzed the pattern of small RNA expression in vivo using latently RRV-infected B-cell lymphoma and retroperitoneal fibromatosis tissues.

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
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  • (PMID = 20655562.001).
  • [ISSN] 1096-0341
  • [Journal-full-title] Virology
  • [ISO-abbreviation] Virology
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA132638; United States / NIAID NIH HHS / AI / R01-AI067968; United States / NIAID NIH HHS / AI / R01 AI067968; United States / NCI NIH HHS / CA / CA075922-14; United States / NCRR NIH HHS / RR / P51 RR000163; United States / NCI NIH HHS / CA / R01 CA132638-03; United States / NCI NIH HHS / CA / R01-CA075922; United States / NCI NIH HHS / CA / R01 CA075922-14; United States / NCI NIH HHS / CA / T32 CA009111; United States / NCRR NIH HHS / RR / K01 RR000163; United States / NCI NIH HHS / CA / T32-CA009111; United States / NCRR NIH HHS / RR / RR000163; United States / NCI NIH HHS / CA / R01 CA075922; United States / NCI NIH HHS / CA / CA132638-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MicroRNAs; 0 / RNA, Viral
  • [Other-IDs] NLM/ NIHMS219827; NLM/ PMC2923253
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87. Bielefeldt-Ohmann H, Barouch DH, Bakke AM, Bruce AG, Durning M, Grant R, Letvin NL, Ryan JT, Schmidt A, Thouless ME, Rose TM: Intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (Macaca mulatta). Vet Pathol; 2005 May;42(3):391-6
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  • Polymerase chain reaction analysis of DNA from tumor and spleen tissue revealed abundant, preferential presence of retroperitoneal fibromatosis herpesvirus, the macaque homologue of the Kaposi sarcoma-associated herpesvirus (human herpesvirus-8), in the tumors.
  • This was corroborated by demonstration of viral latent nuclear antigen-1 in the nuclei of a majority of the spindeloid tumor cells.
  • Low levels of an additional macaque herpesvirus, rhesus rhadinovirus, were also detected in the spleen and tumor tissues.

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  • (PMID = 15872392.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / K02-AI49275; United States / NIAID NIH HHS / AI / N01-AI-15431; United States / NCRR NIH HHS / RR / P51RR00166; United States / NCRR NIH HHS / RR / R01-RR13154
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Nuclear; 0 / DNA Primers; 0 / Vimentin
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88. Bruce AG, Bakke AM, Thouless ME, Rose TM: Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons. Virol J; 2005 Jan 05;2:2
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  • These primers showed little similarity to the corresponding sequences of the macaque RV1 rhadinoviruses, retroperitoneal fibromatosis herpesvirus Macaca nemestrina (RFHVMn) and Macaca mulatta (RFHVMm).

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  • (PMID = 15634356.001).
  • [ISSN] 1743-422X
  • [Journal-full-title] Virology journal
  • [ISO-abbreviation] Virol. J.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / RR13154; United States / NCRR NIH HHS / RR / P51 RR000166; United States / NCRR NIH HHS / RR / R24 RR023343; United States / NIAID NIH HHS / AI / K02 AI49275; United States / NCRR NIH HHS / RR / R01 RR013154; United States / NIAID NIH HHS / AI / K02 AI049275; United States / NCRR NIH HHS / RR / RR00166
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC544863
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89. Yang CH, Sheen-Chen SM, Lu CC, Ko SF, Eng HL: Computed tomographic presentation of mesenteric fibromatosis. Dig Dis Sci; 2005 Feb;50(2):348-50
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  • [Title] Computed tomographic presentation of mesenteric fibromatosis.

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  • (PMID = 15745099.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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90. Azizi L, Balu M, Belkacem A, Lewin M, Tubiana JM, Arrivé L: MRI features of mesenteric desmoid tumors in familial adenomatous polyposis. AJR Am J Roentgenol; 2005 Apr;184(4):1128-35
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  • [Title] MRI features of mesenteric desmoid tumors in familial adenomatous polyposis.
  • [MeSH-major] Adenomatous Polyposis Coli / surgery. Fibromatosis, Abdominal / pathology. Magnetic Resonance Imaging. Mesentery / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans


91. Doi J, Morita S: A case of mesenteric desmoid tumor of the jejunum. Jpn J Clin Oncol; 2009 Dec;39(12):859
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  • [Title] A case of mesenteric desmoid tumor of the jejunum.
  • [MeSH-major] Fibromatosis, Abdominal / epidemiology. Peritoneal Neoplasms / epidemiology

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  • (PMID = 19942588.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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92. Lo KW: Mesenteric fibromatosis as a potential source of false-positive interpretation of FDG-PET: report of a case. Dis Colon Rectum; 2007 Jun;50(6):924-6
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  • [Title] Mesenteric fibromatosis as a potential source of false-positive interpretation of FDG-PET: report of a case.

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  • (PMID = 17205200.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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93. Gómez Cabeza de Vaca V, Molina García D, Cañete Gómez J, López Bernal F, Flores Cortés M, Palacios González C, Prendes Sillero E, Pareja Ciuró F: [Mesenteric fibromatosis: a rare entity]. Rev Esp Enferm Dig; 2009 Jul;101(7):506-7
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  • [Title] [Mesenteric fibromatosis: a rare entity].
  • [Transliterated title] Fibromatosis mesentérica en el contexto de postoperatorio de colecistitits aguda.
  • [MeSH-minor] Acute Disease. Aged. Cholecystitis / surgery. Female. Humans. Postoperative Complications / diagnosis. Postoperative Complications / surgery

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  • (PMID = 19642844.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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94. Xu HM, Han JG, Ma SZ, Zhao B, Pang GY, Wang ZJ: Treatment of massive desmoid tumour and abdominal wall reconstructed with meshes in Gardner's Syndrome. J Plast Reconstr Aesthet Surg; 2010 Jun;63(6):1058-60
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  • [Title] Treatment of massive desmoid tumour and abdominal wall reconstructed with meshes in Gardner's Syndrome.
  • [MeSH-major] Abdominal Wall. Fibromatosis, Abdominal / pathology. Fibromatosis, Abdominal / surgery. Gardner Syndrome / surgery. Reconstructive Surgical Procedures / methods. Surgical Mesh

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  • (PMID = 19527947.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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95. Ayhan S, Temız P, Kurt K: Mesenteric fibromatosis: a case report. Turk J Gastroenterol; 2010 Jun;21(2):193-5
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  • [Title] Mesenteric fibromatosis: a case report.

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  • (PMID = 20872340.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Turkey
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96. Solazzo M, Marcianò P, Benzi F, Puccio F: Ileal resection and small bowel transplantation for large mesenteric desmoid tumor. Tech Coloproctol; 2005 Apr;9(1):72-3
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  • [Title] Ileal resection and small bowel transplantation for large mesenteric desmoid tumor.
  • [MeSH-major] Fibromatosis, Aggressive / surgery. Ileum / surgery. Intestine, Small / transplantation. Mesentery. Peritoneal Neoplasms / surgery

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  • (PMID = 15884154.001).
  • [ISSN] 1123-6337
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Italy
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97. Prat A, Peralta S, Cuéllar H, Ocaña A: Hepatic pneumatosis as a complication of an abdominal desmoid tumor. J Clin Oncol; 2007 Mar 1;25(7):897-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic pneumatosis as a complication of an abdominal desmoid tumor.
  • [MeSH-major] Fibromatosis, Abdominal / complications. Liver Diseases / etiology
  • [MeSH-minor] Adult. Gases. Humans. Male. Radiography, Abdominal. Tomography, X-Ray Computed

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  • (PMID = 17327611.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gases
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98. Polat C, Aktepe F, Turel S, Yazicioglu B, Ozkececi T, Arikan Y: A giant mesenteric fibromatosis case presenting with mechanical intestinal obstruction and successfully resected with partial duodeno-jejunectomy and right hemicolectomy. Clinics (Sao Paulo); 2010;65(1):110-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A giant mesenteric fibromatosis case presenting with mechanical intestinal obstruction and successfully resected with partial duodeno-jejunectomy and right hemicolectomy.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Intestinal Obstruction / etiology. Mesentery / pathology. Peritoneal Neoplasms / pathology
  • [MeSH-minor] Colectomy / methods. Diagnosis, Differential. Duodenum / surgery. Humans. Jejunum / surgery. Male. Middle Aged

  • Genetic Alliance. consumer health - Fibromatosis.
  • MedlinePlus Health Information. consumer health - Intestinal Obstruction.
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  • (PMID = 20126354.001).
  • [ISSN] 1980-5322
  • [Journal-full-title] Clinics (São Paulo, Brazil)
  • [ISO-abbreviation] Clinics (Sao Paulo)
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Brazil
  • [Other-IDs] NLM/ PMC2815273
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99. McGregor JC: Extra abdominal desmoid tumour--a long term follow up--further comment. J Plast Reconstr Aesthet Surg; 2006;59(2):208
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extra abdominal desmoid tumour--a long term follow up--further comment.
  • [MeSH-major] Fibromatosis, Aggressive / therapy. Soft Tissue Neoplasms / therapy

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  • [CommentOn] Br J Plast Surg. 2004 Jun;57(4):362-5 [15145742.001]
  • (PMID = 16703872.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Netherlands
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