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1. Staal-Viliare A, Latger-Cannard V, Rault JP, Didion J, Grégoire MJ, Bologna S, Witz B, Jonveaux P, Lecompte T, Rio Y: [A case of de novo acute basophilic leukaemia: diagnostic criteria and review of the literature]. Ann Biol Clin (Paris); 2006 Jul-Aug;64(4):361-5
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  • [Title] [A case of de novo acute basophilic leukaemia: diagnostic criteria and review of the literature].
  • [Transliterated title] A propos d'un cas de leucémie à basophiles de novo: critères diagnostiques et revue de la littérature.
  • We report a case of a de novo acute basophilic leukaemia, revealed by an infectious pneumopathy in a 73 year old man.
  • The blood and bone marrow smears showed a mixture of undifferentiated blast cells and basophiloblasts (high nucleo-cytoplasmic ratio, coarse basophilic cytoplasmic granules), along with basophilic precursors and basophilic polymorphonuclears.
  • All the blasts were MPO negative but positive for the toluidine blue metachromatic coloration, which is considered as consistent with basophilic lineage.
  • Immunophenotypic studies showed myeloid blasts, without maturity marker, CD 117 negative and CD203 cytoplasmic positive, the latter known to be highly representative of the basophilic lineage.
  • This very clear-cut phenotype, associated with the morphology of cells, were arguments to ascertain the basophilic lineage of the blasts without the need of electron microscopic study.
  • This clinical prompted allows us to review the literature on acute basophilic leukaemia and to state on the different diagnostic criteria of this rare disorder.
  • [MeSH-major] Leukemia, Basophilic, Acute / blood. Leukemia, Basophilic, Acute / diagnosis

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  • (PMID = 16829481.001).
  • [ISSN] 0003-3898
  • [Journal-full-title] Annales de biologie clinique
  • [ISO-abbreviation] Ann. Biol. Clin. (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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2. Lippert U, Ferrari DM, Jahn R: Endobrevin/VAMP8 mediates exocytotic release of hexosaminidase from rat basophilic leukaemia cells. FEBS Lett; 2007 Jul 24;581(18):3479-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endobrevin/VAMP8 mediates exocytotic release of hexosaminidase from rat basophilic leukaemia cells.
  • We used permeabilized rat basophilic leukaemia cells as model to identify R-SNAREs (soluble NSF (N-ethylmaleimide-sensitive fusion protein)) mediating exocytosis of hexosaminidase from mast cells.
  • [MeSH-major] Basophils / metabolism. Exocytosis. Hexosaminidases / metabolism. Hexosaminidases / secretion. Leukemia / metabolism. R-SNARE Proteins / metabolism

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  • (PMID = 17618625.001).
  • [ISSN] 0014-5793
  • [Journal-full-title] FEBS letters
  • [ISO-abbreviation] FEBS Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Bacterial Proteins; 0 / R-SNARE Proteins; 0 / Streptolysins; 0 / Vamp8 protein, rat; 0 / Vesicle-Associated Membrane Protein 2; 0 / Vesicle-Associated Membrane Protein 3; 0 / streptolysin O; EC 3.2.1.- / Hexosaminidases; SY7Q814VUP / Calcium
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3. Xu F, Matsuda H, Hata H, Sugawara K, Nakamura S, Yoshikawa M: Structures of new flavonoids and benzofuran-type stilbene and degranulation inhibitors of rat basophilic leukemia cells from the Brazilian herbal medicine Cissus sicyoides. Chem Pharm Bull (Tokyo); 2009 Oct;57(10):1089-95
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  • [Title] Structures of new flavonoids and benzofuran-type stilbene and degranulation inhibitors of rat basophilic leukemia cells from the Brazilian herbal medicine Cissus sicyoides.
  • The inhibitory effects of the isolated constituents on the release of beta-hexosaminidase as a marker of degranulation in rat basophilic leukemia (RBL-2H3) cells were examined.
  • [MeSH-major] Benzofurans / chemistry. Cell Degranulation / drug effects. Cissus / chemistry. Flavonoids / chemistry. Leukemia / metabolism. Stilbenes / chemistry

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  • (PMID = 19801863.001).
  • [ISSN] 1347-5223
  • [Journal-full-title] Chemical & pharmaceutical bulletin
  • [ISO-abbreviation] Chem. Pharm. Bull.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Benzofurans; 0 / Flavonoids; 0 / Stilbenes; EC 3.2.1.52 / beta-N-Acetylhexosaminidases
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4. Okoshi Y, Tahara-Hanaoka S, Nakahashi C, Honda S, Miyamoto A, Kojima H, Nagasawa T, Shibuya K, Shibuya A: Requirement of the tyrosines at residues 258 and 270 of MAIR-I in inhibitory effect on degranulation from basophilic leukemia RBL-2H3. Int Immunol; 2005 Jan;17(1):65-72
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  • [Title] Requirement of the tyrosines at residues 258 and 270 of MAIR-I in inhibitory effect on degranulation from basophilic leukemia RBL-2H3.
  • Here, we demonstrate that the transfectant of rat basophil leukemia RBL-2H3 expressing wild-type MAIR-I is tyrosine phosphorylated and recruits SHP-1 and SHIP upon cross-linking of MAIR-I.
  • [MeSH-minor] Amino Acid Substitution. Animals. Antibodies, Monoclonal / pharmacology. Cell Line, Tumor. Immunoglobulin E / immunology. Leukemia, Basophilic, Acute. Mutation / genetics. Phosphorylation. Protein Tyrosine Phosphatases / metabolism. Rats

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  • (PMID = 15569773.001).
  • [ISSN] 0953-8178
  • [Journal-full-title] International immunology
  • [ISO-abbreviation] Int. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / MAIR-I, rat; 0 / Receptors, IgE; 0 / Receptors, Polymeric Immunoglobulin; 37341-29-0 / Immunoglobulin E; 42HK56048U / Tyrosine; EC 3.1.3.48 / Protein Tyrosine Phosphatases
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5. Mizuno H, Tsuyama N, Date S, Harada T, Masujima T: Live single-cell metabolomics of tryptophan and histidine metabolites in a rat basophil leukemia cell. Anal Sci; 2008 Dec;24(12):1525-7
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  • [Title] Live single-cell metabolomics of tryptophan and histidine metabolites in a rat basophil leukemia cell.
  • The metabolic pathways and the locations of tryptophan and histidine metabolites were traced by this method for a cultured rat basophil leukemia cell line (RBL-2H3).
  • [MeSH-major] Basophils / metabolism. Basophils / pathology. Histidine / metabolism. Leukemia / metabolism. Leukemia / pathology. Metabolomics. Tryptophan / metabolism

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  • (PMID = 19075459.001).
  • [ISSN] 1348-2246
  • [Journal-full-title] Analytical sciences : the international journal of the Japan Society for Analytical Chemistry
  • [ISO-abbreviation] Anal Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 4QD397987E / Histidine; 8DUH1N11BX / Tryptophan
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6. Lichtman MA, Segel GB: Uncommon phenotypes of acute myelogenous leukemia: basophilic, mast cell, eosinophilic, and myeloid dendritic cell subtypes: a review. Blood Cells Mol Dis; 2005 Nov-Dec;35(3):370-83
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  • [Title] Uncommon phenotypes of acute myelogenous leukemia: basophilic, mast cell, eosinophilic, and myeloid dendritic cell subtypes: a review.
  • The potential of the transformed (leukemic) multipotential hematopoietic cell to differentiate and mature along any myeloid lineage forms the basis for the phenotypic classification of acute and chronic myelogenous leukemia.
  • Although most cases of leukemia can be classified phenotypically by the dominant lineage expressed, the genotype within each phenotype is heterogeneous.
  • The least common AML phenotypes are a reflection of the least common blood or marrow cell lineages: acute basophilic, acute mast cell, acute eosinophilic, and acute myeloid dendritic cell leukemia.
  • [MeSH-major] Basophils / pathology. Dendritic Cells / pathology. Eosinophils / pathology. Leukemia, Myeloid, Acute / genetics. Leukemia, Myeloid, Acute / pathology. Mast Cells / pathology. Myeloid Cells / pathology


7. Yasui Y, Sasao E, Sakata M, Matsui N, Fukuishi N, Akagi R, Akagi M: Upregulation of heme oxygenase-1 by degranulation in rat basophilic leukemia cells. Biol Pharm Bull; 2007 Mar;30(3):443-6
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  • [Title] Upregulation of heme oxygenase-1 by degranulation in rat basophilic leukemia cells.
  • To trigger degranulation, rat basophilic leukemia (RBL)-2H3 cells were passively sensitized using an antiserum collected from ovalbumin (OA) immunized-Brown Norway rats, and the cells were stimulated by treatment with OA.
  • [MeSH-major] Cell Degranulation. Heme Oxygenase-1 / metabolism. Leukemia, Basophilic, Acute / metabolism

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  • (PMID = 17329835.001).
  • [ISSN] 0918-6158
  • [Journal-full-title] Biological & pharmaceutical bulletin
  • [ISO-abbreviation] Biol. Pharm. Bull.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / 2',7'-dichlorodihydrofluorescein diacetate; 0 / Azo Compounds; 0 / Enzyme Inhibitors; 0 / Fluoresceins; 0 / Free Radical Scavengers; 0 / Metalloporphyrins; 0 / RNA, Messenger; 0 / Reactive Oxygen Species; 0KAE1U0G7Q / tin mesoporphyrin; 6226-79-5 / ponceau S; 9006-59-1 / Ovalbumin; EC 1.14.99.3 / Heme Oxygenase-1; WYQ7N0BPYC / Acetylcysteine
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8. Yang W, Chen J, Zhou L: Effects of shear stress on intracellular calcium change and histamine release in rat basophilic leukemia (RBL-2H3) cells. J Environ Pathol Toxicol Oncol; 2009;28(3):223-30
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  • [Title] Effects of shear stress on intracellular calcium change and histamine release in rat basophilic leukemia (RBL-2H3) cells.
  • In the present work, a mast cell line (rat basophilic leukemia cells, RBL-2H3) was used in vitro to study cellular responses to the stimulus of shear stress generated by a rotating rotor in a cell dish.
  • [MeSH-minor] Animals. Calcium Channels / drug effects. Calcium Channels / physiology. Calcium Signaling / drug effects. Calcium Signaling / physiology. Cell Line, Tumor. Cell Membrane / drug effects. Cell Membrane / metabolism. Indicators and Reagents / pharmacology. Leukemia, Basophilic, Acute. Microcirculation. Rats. Ruthenium Red / pharmacology. Stress, Mechanical. TRPV Cation Channels / antagonists & inhibitors. TRPV Cation Channels / metabolism

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  • (PMID = 19888909.001).
  • [ISSN] 2162-6537
  • [Journal-full-title] Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer
  • [ISO-abbreviation] J. Environ. Pathol. Toxicol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium Channels; 0 / Indicators and Reagents; 0 / TRPV Cation Channels; 0 / Trpv4 protein, rat; 11103-72-3 / Ruthenium Red; 820484N8I3 / Histamine; SY7Q814VUP / Calcium
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9. Moser AM, Manor E, Narkis G, Kapelushnik J: Imatinib resistant chronic myelogenous leukemia, BCR-ABL positive by chromosome and FISH analyses but negative by PCR, in a child progressing to acute basophilic leukemia: cytogenetic follow-up. Cancer Genet Cytogenet; 2006 Oct 1;170(1):54-7
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  • [Title] Imatinib resistant chronic myelogenous leukemia, BCR-ABL positive by chromosome and FISH analyses but negative by PCR, in a child progressing to acute basophilic leukemia: cytogenetic follow-up.
  • The case of an 11-year-old child with adult-type chronic myeloid leukemia, Philadelphia (BCR-ABL) positive, reverse transcription-polymerase chain reaction negative for the major, minor, and micro breakpoints is presented.
  • In the course of 3 years, the child failed to respond to treatment with hydroxyurea, refused all therapy for 6 months, was intolerant to alpha-interferon and progressed, while on imatinib, to acute basophilic leukemia.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Genes, abl. Leukemia, Basophilic, Acute / surgery. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics. Piperazines / therapeutic use. Pyrimidines / therapeutic use

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  • (PMID = 16965955.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate
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10. Itoh T, Tsukane M, Koike M, Nakamura C, Ohguchi K, Ito M, Akao Y, Koshimizu S, Nozawa Y, Wakimoto T, Nukaya H, Suwa Y: Inhibitory effects of whisky congeners on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice. J Agric Food Chem; 2010 Jun 23;58(12):7149-57
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  • [Title] Inhibitory effects of whisky congeners on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice.
  • [MeSH-minor] Animals. Basophil Degranulation Test. Cell Degranulation / drug effects. Cell Line, Tumor. Disease Models, Animal. Histamine Release / drug effects. Humans. Male. Mice. Mice, Inbred ICR. Quercus / chemistry. Quercus / immunology. Rats. Skin / immunology

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  • (PMID = 20507065.001).
  • [ISSN] 1520-5118
  • [Journal-full-title] Journal of agricultural and food chemistry
  • [ISO-abbreviation] J. Agric. Food Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Plant Extracts; 37341-29-0 / Immunoglobulin E
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11. Itoh T, Ninomiya M, Nozawa Y, Koketsu M: Chalcone glycosides isolated from aerial parts of Brassica rapa L. 'hidabeni' suppress antigen-stimulated degranulation in rat basophilic leukemia RBL-2H3 cells. Bioorg Med Chem; 2010 Oct 1;18(19):7052-7
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  • [Title] Chalcone glycosides isolated from aerial parts of Brassica rapa L. 'hidabeni' suppress antigen-stimulated degranulation in rat basophilic leukemia RBL-2H3 cells.
  • We isolated three chalcone glycosides along with other glycoside constituents from the aerial parts of Brassica rapa L. 'hidabeni' and examined the effects of these compounds on the antigen-stimulated degranulation in rat basophilic leukemia RBL-2H3 cells.

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20801664.001).
  • [ISSN] 1464-3391
  • [Journal-full-title] Bioorganic & medicinal chemistry
  • [ISO-abbreviation] Bioorg. Med. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens; 0 / Biphenyl Compounds; 0 / Chalcones; 0 / Free Radical Scavengers; 0 / Glycosides; 0 / Picrates; 0 / Plant Extracts; 0 / Reactive Oxygen Species; 1898-66-4 / 2,2-diphenyl-1-picrylhydrazyl; EC 1.6.3.1 / NADPH Oxidase
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12. Itoh T, Ohguchi K, Iinuma M, Nozawa Y, Akao Y: Inhibitory effects of polymethoxy flavones isolated from Citrus reticulate on degranulation in rat basophilic leukemia RBL-2H3: enhanced inhibition by their combination. Bioorg Med Chem; 2008 Aug 15;16(16):7592-8
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  • [Title] Inhibitory effects of polymethoxy flavones isolated from Citrus reticulate on degranulation in rat basophilic leukemia RBL-2H3: enhanced inhibition by their combination.
  • It has been reported that flavonoids isolated from several Citrus have been shown to suppress the degranulation as inferred by histamine release in rat basophilic leukemia RBL-2H3 cells.
  • [MeSH-minor] Animals. Calcium / antagonists & inhibitors. Calcium / metabolism. Cell Line, Tumor. Enzyme Activation / drug effects. Histamine Release / drug effects. Immunoblotting. Intracellular Signaling Peptides and Proteins / antagonists & inhibitors. Intracellular Signaling Peptides and Proteins / metabolism. Leukemia, Basophilic, Acute. Phospholipase C gamma / antagonists & inhibitors. Phospholipase C gamma / metabolism. Protein-Tyrosine Kinases / antagonists & inhibitors. Protein-Tyrosine Kinases / metabolism. Rats. Reactive Oxygen Species / metabolism. Receptors, IgG / metabolism. Signal Transduction / drug effects. src-Family Kinases / antagonists & inhibitors. src-Family Kinases / metabolism

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  • (PMID = 18656366.001).
  • [ISSN] 1464-3391
  • [Journal-full-title] Bioorganic & medicinal chemistry
  • [ISO-abbreviation] Bioorg. Med. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Flavones; 0 / Intracellular Signaling Peptides and Proteins; 0 / Reactive Oxygen Species; 0 / Receptors, IgG; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Syk kinase; EC 2.7.10.2 / lyn protein-tyrosine kinase; EC 2.7.10.2 / src-Family Kinases; EC 3.1.4.3 / Phospholipase C gamma; SY7Q814VUP / Calcium
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13. Cho Y, Jang Y, Yang YD, Lee CH, Lee Y, Oh U: TRPM8 mediates cold and menthol allergies associated with mast cell activation. Cell Calcium; 2010 Oct;48(4):202-8
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  • Here, we report that TRPM8 is expressed in the basophilic leukemia mast cell line, RBL-2H3, and that exposure to menthol or low temperatures induced Ca(2+) influx in RBL-2H3 cells, which was reversed by a TRPM8 blocker.

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20934218.001).
  • [ISSN] 1532-1991
  • [Journal-full-title] Cell calcium
  • [ISO-abbreviation] Cell Calcium
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Aniline Compounds; 0 / Fluorescent Dyes; 0 / RNA, Small Interfering; 0 / TRPM Cation Channels; 0 / Xanthenes; 121714-13-4 / Fluo-3; 1490-04-6 / Menthol; SY7Q814VUP / Calcium
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14. Hirayama T, Kawabe T, Matsushima M, Nishimura Y, Kobe Y, Ota Y, Baba K, Takagi K: Ghrelin and obestatin promote the allergic action in rat peritoneal mast cells as basic secretagogues. Peptides; 2010 Nov;31(11):2109-13

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  • Rat peritoneal mast cells and rat basophilic leukemia (RBL-2H3) cells did not express the ghrelin receptor GHSR1a, suggesting that histamine release induced by ghrelin occurs via a receptor-independent mechanism.

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20691233.001).
  • [ISSN] 1873-5169
  • [Journal-full-title] Peptides
  • [ISO-abbreviation] Peptides
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ghrelin; 0 / Peptide Hormones; 0 / Receptors, Ghrelin; 0 / obestatin, rat; EC 2.4.2.31 / Pertussis Toxin
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15. Cui Y, Hou X, Chen J, Xie L, Yang L, Le Y: Sesamin inhibits bacterial formylpeptide-induced inflammatory responses in a murine air-pouch model and in THP-1 human monocytes. J Nutr; 2010 Feb;140(2):377-81
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  • Similarly, sesamin inhibited FPR-transfected rat basophilic leukemia cell [epitope-tagged human FPR (ETFR) cell] migration toward fMLF (P < 0.01).
  • [MeSH-minor] Animals. Bacteria / metabolism. Basophils / drug effects. Bucladesine. Calcium / metabolism. Cell Line. Cell Line, Tumor. Dose-Response Relationship, Drug. Humans. Inflammation / chemically induced. Inflammation / drug therapy. Inflammation / metabolism. Leukemia / drug therapy. Mice. Mice, Inbred C57BL. Mitogen-Activated Protein Kinase 1 / metabolism. Models, Animal. N-Formylmethionine Leucyl-Phenylalanine. NF-kappa B / antagonists & inhibitors. Phosphorylation. Phytotherapy. Rats. Receptors, Formyl Peptide / metabolism. Signal Transduction / drug effects

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  • (PMID = 20032476.001).
  • [ISSN] 1541-6100
  • [Journal-full-title] The Journal of nutrition
  • [ISO-abbreviation] J. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Dioxoles; 0 / Lignans; 0 / NF-kappa B; 0 / Plant Extracts; 0 / Receptors, Formyl Peptide; 59880-97-6 / N-Formylmethionine Leucyl-Phenylalanine; 63X7MBT2LQ / Bucladesine; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 1; S7946O4P76 / sesamin; SY7Q814VUP / Calcium
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16. Young SM, Bologa CM, Fara D, Bryant BK, Strouse JJ, Arterburn JB, Ye RD, Oprea TI, Prossnitz ER, Sklar LA, Edwards BS: Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes. Cytometry A; 2009 Mar;75(3):253-63
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  • U937 cells expressing FPR and rat basophil leukemia (RBL) cells expressing FPRL1 were tested together in a "duplex" format.

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  • [Copyright] 2008 International Society for Advancement of Cytometry.
  • [Cites] Mol Pharmacol. 2007 Apr;71(4):1061-74 [17229869.001]
  • [Cites] Bioorg Med Chem Lett. 2006 Jul 15;16(14):3713-8 [16697190.001]
  • [Cites] Mol Cancer Ther. 2007 Oct;6(10):2618-25 [17938258.001]
  • [Cites] J Neurooncol. 2008 Jan;86(1):47-53 [17611713.001]
  • [Cites] Mol Pharmacol. 2008 Aug;74(2):392-402 [18458054.001]
  • [Cites] J Exp Med. 2000 Apr 3;191(7):1197-208 [10748237.001]
  • [Cites] Mol Cell. 2000 May;5(5):831-40 [10882119.001]
  • [Cites] Clin Immunol. 2000 Sep;96(3):236-42 [10964542.001]
  • [Cites] J Exp Med. 2000 Oct 2;192(7):1069-74 [11015447.001]
  • [Cites] J Neuroimmunol. 2000 Nov 1;111(1-2):102-8 [11063827.001]
  • [Cites] J Immunol. 2001 Feb 1;166(3):1448-51 [11160182.001]
  • [Cites] J Neurosci. 2001 Jan 15;21(2):RC123 [11160457.001]
  • [Cites] Cytometry. 2001 May 1;44(1):83-90 [11309812.001]
  • [Cites] Cytokine Growth Factor Rev. 2001 Mar;12(1):91-105 [11312121.001]
  • [Cites] J Biol Chem. 2001 Jun 29;276(26):23645-52 [11316806.001]
  • [Cites] FASEB J. 2001 Nov;15(13):2454-62 [11689470.001]
  • [Cites] Trends Biotechnol. 2002 Jan;20(1):9-12 [11742671.001]
  • [Cites] Int Immunopharmacol. 2002 Jan;2(1):1-13 [11789660.001]
  • [Cites] Nat Biotechnol. 2002 Feb;20(2):155-62 [11821861.001]
  • [Cites] Trends Immunol. 2002 Nov;23(11):541-8 [12401407.001]
  • [Cites] Blood. 2003 Feb 15;101(4):1572-81 [12393391.001]
  • [Cites] Cytometry A. 2003 May;53(1):55-65 [12701132.001]
  • [Cites] J Immunol. 2003 Aug 15;171(4):2050-6 [12902510.001]
  • [Cites] Mol Pharmacol. 2004 Nov;66(5):1213-22 [15308762.001]
  • [Cites] J Immunol. 1975 Jun;114(6):1831-7 [165239.001]
  • [Cites] Proc Natl Acad Sci U S A. 1975 Mar;72(3):1059-62 [1093163.001]
  • [Cites] J Exp Med. 1982 Jan 1;155(1):264-75 [6274994.001]
  • [Cites] J Biol Chem. 1984 May 10;259(9):5430-9 [6371005.001]
  • [Cites] J Recept Res. 1988;8(1-4):533-46 [3385692.001]
  • [Cites] Annu Rev Immunol. 1991;9:617-48 [1910690.001]
  • [Cites] J Biol Chem. 1992 Apr 15;267(11):7637-43 [1373134.001]
  • [Cites] Biochem Biophys Res Commun. 1992 Apr 30;184(2):582-9 [1374236.001]
  • [Cites] Genomics. 1992 Jun;13(2):437-40 [1612600.001]
  • [Cites] Int Immunol. 1993 Oct;5(10):1239-49 [7505609.001]
  • [Cites] Annu Rev Immunol. 1994;12:593-633 [8011292.001]
  • [Cites] J Exp Med. 1995 Jul 1;182(1):207-17 [7540650.001]
  • [Cites] J Immunol. 1995 Oct 1;155(7):3292-5 [7561021.001]
  • [Cites] J Neuroimmunol. 1995 Aug;61(1):71-8 [7560015.001]
  • [Cites] Nature. 1996 Mar 28;380(6572):345-7 [8598929.001]
  • [Cites] J Mol Cell Cardiol. 1997 Mar;29(3):881-94 [9152849.001]
  • [Cites] Pharmacol Ther. 1997;74(1):73-102 [9336017.001]
  • [Cites] J Exp Med. 1998 Apr 20;187(8):1285-94 [9547339.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 May 26;95(11):6448-53 [9600986.001]
  • [Cites] Cytometry. 1998 Oct 1;33(2):234-43 [9773885.001]
  • [Cites] J Exp Med. 1999 Jan 18;189(2):395-402 [9892621.001]
  • [Cites] Curr Opin Hematol. 1999 Jan;6(1):15-24 [9915549.001]
  • [Cites] J Exp Med. 1999 Feb 15;189(4):657-62 [9989980.001]
  • [Cites] J Immunol. 1999 May 15;162(10):5924-30 [10229829.001]
  • [Cites] J Natl Cancer Inst. 2005 Jun 1;97(11):823-35 [15928303.001]
  • [Cites] J Biomol Screen. 2005 Jun;10(4):374-82 [15964939.001]
  • [Cites] Mol Pharmacol. 2005 Nov;68(5):1301-10 [16118363.001]
  • [Cites] Nat Methods. 2006 May;3(5):361-8 [16628206.001]
  • [Cites] Mol Pharmacol. 2007 Oct;72(4):976-83 [17652444.001]
  • (PMID = 18785269.001).
  • [ISSN] 1552-4930
  • [Journal-full-title] Cytometry. Part A : the journal of the International Society for Analytical Cytology
  • [ISO-abbreviation] Cytometry A
  • [Language] ENG
  • [Grant] United States / NIMH NIH HHS / MH / U54 MH074425; United States / NIMH NIH HHS / MH / R03 MH076381-01; United States / NIMH NIH HHS / MH / MH076381-01; United States / NIMH NIH HHS / MH / R03 MH076381; United States / NIMH NIH HHS / MH / U54 MH074425-01
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chemotactic Factors; 0 / FPR2 protein, human; 0 / Fluorescent Dyes; 0 / Ligands; 0 / Molecular Probes; 0 / Receptors, Formyl Peptide; 0 / Receptors, Lipoxin
  • [Other-IDs] NLM/ NIHMS76367; NLM/ PMC2645486
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17. Fowler CJ, Ghafouri N: Does the hydrolysis of 2-arachidonoylglycerol regulate its cellular uptake? Pharmacol Res; 2008 Jul;58(1):72-6
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  • The selective fatty acid amide hydrolase inhibitor URB597 (3'-(aminocarbamoyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate) completely blocked the hydrolysis of anandamide and reduced its uptake by about half in RBL2H3 basophilic leukaemia cells.

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  • (PMID = 18675915.001).
  • [ISSN] 1043-6618
  • [Journal-full-title] Pharmacological research
  • [ISO-abbreviation] Pharmacol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Arachidonic Acids; 0 / Benzamides; 0 / Biphenyl Compounds; 0 / Cannabinoid Receptor Modulators; 0 / Carbamates; 0 / Endocannabinoids; 0 / Glycerides; 0 / Polyunsaturated Alkamides; 0 / URB602; 0 / cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester; 53847-30-6 / 2-arachidonylglycerol; 94421-68-8 / anandamide; EC 3.5.- / Amidohydrolases; EC 3.5.1.- / fatty-acid amide hydrolase
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18. Ong HL, Cheng KT, Liu X, Bandyopadhyay BC, Paria BC, Soboloff J, Pani B, Gwack Y, Srikanth S, Singh BB, Gill DL, Ambudkar IS: Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. J Biol Chem; 2007 Mar 23;282(12):9105-16
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

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  • Store-operated calcium entry (SOCE) is a ubiquitous mechanism that is mediated by distinct SOC channels, ranging from the highly selective calcium release-activated Ca2+ (CRAC) channel in rat basophilic leukemia and other hematopoietic cells to relatively Ca2+-selective or non-selective SOC channels in other cells.

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  • [Cites] J Biol Chem. 1999 Dec 24;274(52):37370-8 [10601307.001]
  • [Cites] Biochim Biophys Acta. 2006 Nov;1763(11):1147-60 [17034882.001]
  • [Cites] J Biol Chem. 2000 Feb 4;275(5):3403-11 [10652333.001]
  • [Cites] J Biol Chem. 2000 Apr 21;275(16):11934-42 [10766822.001]
  • [Cites] Circ Res. 2001 Jan 19;88(1):84-7 [11139478.001]
  • [Cites] Annu Rev Immunol. 2001;19:497-521 [11244045.001]
  • [Cites] FASEB J. 2001 Jul;15(9):1652-4 [11427516.001]
  • [Cites] J Exp Med. 2002 Mar 18;195(6):673-81 [11901194.001]
  • [Cites] Biochim Biophys Acta. 2002 Apr 1;1596(1):131-7 [11983428.001]
  • [Cites] Nat Cell Biol. 2002 Nov;4(11):E263-72 [12415286.001]
  • [Cites] J Biol Chem. 2003 Mar 28;278(13):11337-43 [12536150.001]
  • [Cites] Nat Rev Mol Cell Biol. 2003 Jul;4(7):517-29 [12838335.001]
  • [Cites] J Biol Chem. 2003 Jul 18;278(29):27208-15 [12732636.001]
  • [Cites] J Biol Chem. 2003 Jul 18;278(29):26629-38 [12736256.001]
  • [Cites] J Biol Chem. 2003 Aug 29;278(35):33492-500 [12766172.001]
  • [Cites] Cell. 2003 Sep 19;114(6):777-89 [14505576.001]
  • [Cites] Sci STKE. 2004 Jul 27;2004(243):pe34 [15280576.001]
  • [Cites] Physiol Rev. 1997 Oct;77(4):901-30 [9354808.001]
  • [Cites] J Biol Chem. 1998 Dec 11;273(50):33295-304 [9837902.001]
  • [Cites] Am J Physiol. 1999 Apr;276(4 Pt 1):C969-79 [10199829.001]
  • [Cites] J Membr Biol. 2004 Jul 15;200(2):93-104 [15520907.001]
  • [Cites] Sci STKE. 2005 Feb 22;2005(272):re3 [15728426.001]
  • [Cites] Physiol Rev. 2005 Apr;85(2):757-810 [15788710.001]
  • [Cites] J Cell Biol. 2005 May 9;169(3):435-45 [15866891.001]
  • [Cites] J Biol Chem. 2005 Jun 3;280(22):21600-6 [15834157.001]
  • [Cites] Curr Biol. 2005 Jul 12;15(13):1235-41 [16005298.001]
  • [Cites] J Biol Chem. 2005 Aug 19;280(33):29559-69 [15972814.001]
  • [Cites] Pflugers Arch. 2005 Oct;451(1):53-60 [15965706.001]
  • [Cites] Pflugers Arch. 2005 Oct;451(1):116-24 [16044307.001]
  • [Cites] Thromb Haemost. 2005 Oct;94(4):839-45 [16270640.001]
  • [Cites] Sci STKE. 2005 Dec 6;2005(313):pe53 [16333017.001]
  • [Cites] Trends Pharmacol Sci. 2006 Jan;27(1):25-32 [16337693.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4040-5 [16537481.001]
  • [Cites] J Pharmacol Exp Ther. 2006 May;317(2):488-99 [16415091.001]
  • [Cites] Nature. 2006 May 11;441(7090):179-85 [16582901.001]
  • [Cites] Science. 2006 May 26;312(5777):1220-3 [16645049.001]
  • [Cites] Nat Cell Biol. 2006 Jul;8(7):771-3 [16733527.001]
  • [Cites] J Biol Chem. 2006 Jul 28;281(30):20661-5 [16766533.001]
  • [Cites] J Biol Chem. 2006 Aug 25;281(34):24979-90 [16807233.001]
  • [Cites] Nat Cell Biol. 2006 Sep;8(9):1003-10 [16906149.001]
  • [Cites] J Cell Biol. 2006 Sep 11;174(6):803-13 [16966422.001]
  • [Cites] J Cell Biol. 2006 Sep 11;174(6):815-25 [16966423.001]
  • [Cites] Nature. 2006 Sep 14;443(7108):230-3 [16921383.001]
  • [Cites] Nature. 2006 Sep 14;443(7108):226-9 [16921385.001]
  • [Cites] J Biol Chem. 2006 Sep 22;281(38):28254-64 [16870612.001]
  • [Cites] Curr Biol. 2006 Oct 24;16(20):2073-9 [16978865.001]
  • [ErratumIn] J Biol Chem. 2007 Sep 14;282(37):27556. Gill, Donald [corrected to Gill, Donald L]
  • (PMID = 17224452.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] ENG
  • [Grant] United States / NIDCR NIH HHS / DE / R01 DE017102-06A1; United States / NIDCR NIH HHS / DE / R01 DE017102; United States / NIDCR NIH HHS / DE / R01 DE017102-03; United States / NCRR NIH HHS / RR / RR017699-077011; United States / NIDCR NIH HHS / DE / R01 DE017102-01A1; United States / NIDCR NIH HHS / DE / R01 DE017102-02; United States / NIDCR NIH HHS / DE / DE017102; United States / NCRR NIH HHS / RR / P20 RR017699; United States / NIGMS NIH HHS / GM / GM07525; United States / NCRR NIH HHS / RR / P20 RR017699-077011; United States / NIDCR NIH HHS / DE / R01 DE017102-05
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium Channels; 0 / Membrane Glycoproteins; 0 / Membrane Proteins; 0 / Neoplasm Proteins; 0 / ORAI1 protein, human; 0 / STIM1 protein, human; 0 / Stim1 protein, mouse; 67526-95-8 / Thapsigargin; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ NIHMS112595; NLM/ PMC3309402
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19. Lehmann K, Schweimer K, Reese G, Randow S, Suhr M, Becker WM, Vieths S, Rösch P: Structure and stability of 2S albumin-type peanut allergens: implications for the severity of peanut allergic reactions. Biochem J; 2006 May 1;395(3):463-72
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  • Even though IgE antibody-binding capacity was reduced by protease treatment, the mediator release from a functional equivalent of a mast cell or basophil, the humanized RBL (rat basophilic leukaemia) cell, demonstrated that this reduction in IgE antibody-binding capacity does not necessarily translate into reduced allergenic potency.

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  • [Cites] J Allergy Clin Immunol. 1991 Aug;88(2):172-9 [1880317.001]
  • [Cites] J Protein Chem. 2000 May;19(4):249-54 [11043929.001]
  • [Cites] J Mol Biol. 1993 Jun 5;231(3):877-87 [8515457.001]
  • [Cites] Eur J Biochem. 1994 Dec 1;226(2):413-22 [8001559.001]
  • [Cites] Structure. 1995 Feb 15;3(2):189-99 [7735835.001]
  • [Cites] Protein Sci. 1996 Apr;5(4):565-77 [8845747.001]
  • [Cites] J Mol Graph. 1996 Feb;14(1):33-8, 27-8 [8744570.001]
  • [Cites] J Mol Graph. 1996 Feb;14(1):51-5, 29-32 [8744573.001]
  • [Cites] Biochemistry. 1996 Dec 10;35(49):15672-82 [8961930.001]
  • [Cites] Planta. 1996;200(4):373-9 [9004547.001]
  • [Cites] J Am Chem Soc. 2001 May 2;123(17):3903-18 [11457140.001]
  • [Cites] Allergy. 2002 Mar;57(3):228-35 [11906337.001]
  • [Cites] Nat Rev Immunol. 2002 Jun;2(6):446-53 [12093011.001]
  • [Cites] J Biol Chem. 2002 Sep 20;277(38):35267-73 [12011089.001]
  • [Cites] Curr Opin Immunol. 2002 Dec;14(6):718-27 [12413521.001]
  • [Cites] Biochem Soc Trans. 2002 Nov;30(Pt 6):906-10 [12440943.001]
  • [Cites] J Allergy Clin Immunol. 2002 Dec;110(6):915-20 [12464959.001]
  • [Cites] Int Arch Allergy Immunol. 2003 May;131(1):14-8 [12759484.001]
  • [Cites] Protein Expr Purif. 2003 Oct;31(2):250-9 [14550644.001]
  • [Cites] Biochemistry. 2003 Dec 2;42(47):13839-47 [14636051.001]
  • [Cites] J Biomol NMR. 2004 May;29(1):93-4 [15017144.001]
  • [Cites] J Allergy Clin Immunol. 2004 May;113(5):805-19; quiz 820 [15131561.001]
  • [Cites] Biochemistry. 2004 Jun 8;43(22):6976-86 [15170335.001]
  • [Cites] Immunochemistry. 1972 Oct;9(10):1021-30 [4538963.001]
  • [Cites] J Agric Food Chem. 1979 May-Jun;27(3):500-3 [582177.001]
  • [Cites] J Mol Biol. 1985 Jun 5;183(3):499-502 [4020867.001]
  • [Cites] Structure. 1997 Feb 15;5(2):291-306 [9032083.001]
  • [Cites] Pept Res. 1996 Nov-Dec;9(6):308-14 [9048425.001]
  • [Cites] Arch Biochem Biophys. 1997 Jun 15;342(2):244-53 [9186485.001]
  • [Cites] J Allergy Clin Immunol. 1997 Jun;99(6 Pt 1):744-51 [9215240.001]
  • [Cites] Biochemistry. 1997 Nov 4;36(44):13503-11 [9354618.001]
  • [Cites] Clin Rev Allergy Immunol. 1997 Winter;15(4):375-87 [9484575.001]
  • [Cites] Electrophoresis. 1997 Dec;18(15):2714-23 [9504803.001]
  • [Cites] J Mol Biol. 1998 Feb 20;276(2):437-48 [9512714.001]
  • [Cites] Nat Biotechnol. 1996 Oct;14(10):1269-73 [9631091.001]
  • [Cites] Nahrung. 1998 Aug;42(3-4):125-7 [9739551.001]
  • [Cites] Nat Struct Biol. 1998 Dec;5(12):1065-74 [9846877.001]
  • [Cites] J Clin Invest. 1999 Feb;103(4):535-42 [10021462.001]
  • [Cites] Int Arch Allergy Immunol. 1999 Feb-Apr;118(2-4):313-4 [10224425.001]
  • [Cites] Allergy. 1999 Apr;54(4):380-5 [10371098.001]
  • [Cites] Int Arch Allergy Immunol. 1999 Aug;119(4):265-74 [10474031.001]
  • [Cites] J Allergy Clin Immunol. 2004 Dec;114(6):1410-7 [15577846.001]
  • [Cites] Int Arch Allergy Immunol. 2005 Jan;136(1):16-22 [15591809.001]
  • [Cites] Mol Nutr Food Res. 2004 Oct;48(5):390-9 [15672479.001]
  • [Cites] Allergy. 2005 Aug;60(8):1021-8 [15969682.001]
  • [Cites] Allergy Asthma Proc. 2005 Mar-Apr;26(2):145-7 [15971474.001]
  • [Cites] Eur J Biochem. 2000 Feb;267(4):1117-24 [10672021.001]
  • [Cites] Acta Crystallogr D Biol Crystallogr. 2000 Mar;56(Pt 3):287-93 [10713515.001]
  • [Cites] J Allergy Clin Immunol. 2000 Mar;105(3):582-6 [10719311.001]
  • [Cites] Protein Expr Purif. 2000 Aug;19(3):419-24 [10910733.001]
  • [Cites] J Allergy Clin Immunol. 2000 Aug;106(2):228-38 [10932064.001]
  • [Cites] J Allergy Clin Immunol. 1992 Dec;90(6 Pt 1):962-9 [1460200.001]
  • (PMID = 16372900.001).
  • [ISSN] 1470-8728
  • [Journal-full-title] The Biochemical journal
  • [ISO-abbreviation] Biochem. J.
  • [Language] eng
  • [Databank-accession-numbers] PDB/ 1W2Q
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 2S Albumins, Plant; 0 / Allergens; 0 / Antigens, Plant; 0 / Ara h 2 allergen, Arachis hypogaea; 0 / Ara h 6 allergen, Arachis hypogaea; 0 / Glycoproteins; 0 / Plant Proteins; 37341-29-0 / Immunoglobulin E; EC 3.4.- / Peptide Hydrolases
  • [Other-IDs] NLM/ PMC1462689
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20. Zhou Y, Bian X, Le Y, Gong W, Hu J, Zhang X, Wang L, Iribarren P, Salcedo R, Howard OM, Farrar W, Wang JM: Formylpeptide receptor FPR and the rapid growth of malignant human gliomas. J Natl Cancer Inst; 2005 Jun 1;97(11):823-35
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  • Endogenous FPR agonist activity released by necrotic tumor cells was assessed by measuring FPR activation in an FPR-transfected basophil leukemia cell line and live U-87 cells.

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  • (PMID = 15928303.001).
  • [ISSN] 1460-2105
  • [Journal-full-title] Journal of the National Cancer Institute
  • [ISO-abbreviation] J. Natl. Cancer Inst.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CO / N01-CO-12400
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Small Interfering; 0 / Receptors, Formyl Peptide; 0 / Vascular Endothelial Growth Factor A
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21. Ueda N, Tsuboi K, Lambert DM: A second N-acylethanolamine hydrolase in mammalian tissues. Neuropharmacology; 2005 Jun;48(8):1079-85
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  • The inhibitor was a useful tool to distinguish the acid amidase from FAAH with rat basophilic leukemia (RBL-1) cells that express both the enzymes.

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  • (PMID = 15910884.001).
  • [ISSN] 1873-7064
  • [Journal-full-title] Neuropharmacology
  • [ISO-abbreviation] Neuropharmacology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Arachidonic Acids; 0 / Endocannabinoids; 0 / Ethanolamines; 0 / Organophosphonates; 0 / Palmitic Acids; 0 / methyl arachidonylfluorophosphonate; 57KD15003I / Phenylmethylsulfonyl Fluoride; 6R8T1UDM3V / palmidrol; EC 3.5.- / Amidohydrolases; EC 3.5.1.- / N-acylethanolamine amidohydrolase; EC 3.5.1.- / fatty-acid amide hydrolase; T8ID5YZU6Y / Dithiothreitol
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22. Hashimoto Y, Arai I, Tanaka M, Nakaike S: Prostaglandin D2 inhibits IgE-mediated scratching by suppressing histamine release from mast cells. J Pharmacol Sci; 2005 May;98(1):90-3
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  • Effects of prostaglandin (PG) D(2), PGE(2), and PGI(2) on itch-associated scratching responses of mice and histamine release from the rat basophilic leukemia cell line RBL-2H3 were examined.

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  • (PMID = 15879676.001).
  • [ISSN] 1347-8613
  • [Journal-full-title] Journal of pharmacological sciences
  • [ISO-abbreviation] J. Pharmacol. Sci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 37341-29-0 / Immunoglobulin E; RXY07S6CZ2 / Prostaglandin D2
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23. Jolly PS, Bektas M, Watterson KR, Sankala H, Payne SG, Milstien S, Spiegel S: Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors. Blood; 2005 Jun 15;105(12):4736-42
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  • Surprisingly, overexpression of SphK1 in rat basophilic leukemia (RBL)-2H3 mast cells impaired degranulation as well as migration toward antigen.

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  • [Cites] J Biol Chem. 2002 Sep 20;277(38):35257-62 [12124383.001]
  • [Cites] Annu Rev Immunol. 2005;23:127-59 [15771568.001]
  • [Cites] Nat Rev Mol Cell Biol. 2003 May;4(5):397-407 [12728273.001]
  • [Cites] Prog Lipid Res. 2003 Jul;42(4):344-57 [12790117.001]
  • [Cites] EMBO J. 2003 Oct 15;22(20):5491-500 [14532121.001]
  • [Cites] J Biol Chem. 2003 Nov 21;278(47):46452-60 [12963721.001]
  • [Cites] Nature. 2004 Jan 22;427(6972):355-60 [14737169.001]
  • [Cites] Circ Res. 2004 Apr 2;94(6):724-34 [15059942.001]
  • [Cites] J Exp Med. 2004 Apr 5;199(7):959-70 [15067032.001]
  • [Cites] Am J Physiol Cell Physiol. 2004 May;286(5):C1130-8 [15075212.001]
  • [Cites] Semin Cell Dev Biol. 2004 Jun;15(3):309-23 [15125894.001]
  • [Cites] J Biol Chem. 2004 May 14;279(20):20555-8 [15023998.001]
  • [Cites] Curr Opin Cell Biol. 2004 Apr;16(2):162-8 [15196559.001]
  • [Cites] Nat Immunol. 2004 Jul;5(7):713-20 [15184895.001]
  • [Cites] J Leukoc Biol. 2004 Jul;76(1):30-5 [14982946.001]
  • [Cites] Nat Rev Cancer. 2004 Aug;4(8):604-16 [15286740.001]
  • [Cites] Nature. 1993 Oct 7;365(6446):557-60 [8413613.001]
  • [Cites] J Cell Biol. 1999 Nov 1;147(3):545-58 [10545499.001]
  • [Cites] Cancer Res. 1999 Dec 15;59(24):6185-91 [10626811.001]
  • [Cites] J Biol Chem. 2000 Oct 27;275(43):33945-50 [10944534.001]
  • [Cites] Curr Biol. 2000 Nov 30;10(23):1527-30 [11114522.001]
  • [Cites] J Neurochem. 2001 Mar;76(5):1573-84 [11238741.001]
  • [Cites] FASEB J. 2001 Dec;15(14):2649-59 [11726541.001]
  • [Cites] J Biol Chem. 2002 Feb 22;277(8):6667-75 [11741921.001]
  • [Cites] Science. 2002 Apr 12;296(5566):346-9 [11923495.001]
  • [Cites] J Biol Chem. 2002 May 10;277(19):17255-62 [11856736.001]
  • [Cites] J Biol Chem. 2002 Jun 14;277(24):21453-7 [11967257.001]
  • [Cites] Nature. 1996 Apr 18;380(6575):634-6 [8602265.001]
  • [Cites] Nature. 1996 Jun 27;381(6585):800-3 [8657285.001]
  • [Cites] J Biol Chem. 1998 May 15;273(20):12576-83 [9575218.001]
  • [Cites] J Immunol. 1998 May 15;160(10):5136-44 [9590266.001]
  • [Cites] Anal Biochem. 1999 Jul 15;272(1):80-6 [10405296.001]
  • [Cites] J Exp Med. 1999 Jul 5;190(1):1-8 [10429665.001]
  • [Cites] J Biol Chem. 2003 Feb 21;278(8):6282-90 [12480944.001]
  • (PMID = 15741218.001).
  • [ISSN] 0006-4971
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / AIS0094; United States / NCI NIH HHS / CA / P30 CA16059
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cross-Linking Reagents; 0 / Culture Media, Serum-Free; 0 / Ligands; 0 / Proto-Oncogene Proteins; 0 / Receptors, IgE; 0 / Receptors, Lysosphingolipid; 37341-29-0 / Immunoglobulin E; 37589-80-3 / Guanosine 5'-O-(3-Thiotriphosphate); EC 2.7.1.- / Phosphotransferases (Alcohol Group Acceptor); EC 2.7.1.- / sphingosine kinase; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 1; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 3; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases; EC 3.6.5.1 / GTP-Binding Protein alpha Subunit, Gi2; EC 3.6.5.1 / GTP-Binding Protein alpha Subunits, Gi-Go; EC 3.6.5.1 / GTP-Binding Protein alpha Subunits, Gq-G11; EC 3.6.5.1 / Gnai2 protein, rat; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ PMC1894993
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24. Morikawa T, Xu F, Matsuda H, Yoshikawa M: Structures of novel norstilbene dimer, longusone A, and three new stilbene dimers, longusols A, B, and C, with antiallergic and radical scavenging activities from Egyptian natural medicine Cyperus longus. Chem Pharm Bull (Tokyo); 2010 Oct;58(10):1379-85
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  • Among the isolates, longusol B (IC(50)=96 µM), luteolin (3.0 µM), resveratrol (17 µM), piceatannol (24 µM), and cassigarols E (84 µM) and G (84 µM) were found to inhibit the release of β-hexosaminidase, as a marker of antigen-induced degranulations, in rat basophilic leukemia (RBL-2H3) cells.

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  • (PMID = 20930408.001).
  • [ISSN] 1347-5223
  • [Journal-full-title] Chemical & pharmaceutical bulletin
  • [ISO-abbreviation] Chem. Pharm. Bull.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Anti-Allergic Agents; 0 / Free Radical Scavengers; 0 / Stilbenes; EC 3.2.1.52 / beta-N-Acetylhexosaminidases
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25. Baumann MJ, Eggel A, Amstutz P, Stadler BM, Vogel M: DARPins against a functional IgE epitope. Immunol Lett; 2010 Oct 30;133(2):78-84
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  • Furthermore, anti-IgE DARPins were shown to inhibit proinflammatory mediator release from rat basophilic leukemia cells expressing human high-affinity IgE receptors with higher efficacy than the monoclonal anti-IgE antibody omalizumab.

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  • [Copyright] Copyright © 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20673836.001).
  • [ISSN] 1879-0542
  • [Journal-full-title] Immunology letters
  • [ISO-abbreviation] Immunol. Lett.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies, Anti-Idiotypic; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / DARPin E2 79; 0 / Epitopes, B-Lymphocyte; 0 / Immunoglobulin Constant Regions; 0 / Recombinant Fusion Proteins; 2P471X1Z11 / Omalizumab; 37341-29-0 / Immunoglobulin E
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26. Ye N, Wang MW, Qin J, Lin B: Microfluidic devices for characterizing the agonist of formyl peptide receptor in RBL-FPR cells. Biomed Microdevices; 2010 Jun;12(3):513-21
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  • This work proposed a microfluidic-based method to characterize FPR-related cellular events in response to small peptides, N-formyl-Met-Leu-Phe (fMLF), in rat basophilic leukemia cell line RBL-2H3 expressing human FPR (RBL-FPR).
  • [MeSH-major] Drug Evaluation, Preclinical / instrumentation. Immunoassay / instrumentation. Leukemia, Basophilic, Acute / immunology. Microfluidic Analytical Techniques / instrumentation. Protein Interaction Mapping / instrumentation. Receptors, Formyl Peptide / drug effects. Receptors, Formyl Peptide / immunology

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  • (PMID = 20195765.001).
  • [ISSN] 1572-8781
  • [Journal-full-title] Biomedical microdevices
  • [ISO-abbreviation] Biomed Microdevices
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Formyl Peptide
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27. Heneberg P, Dráberová L, Bambousková M, Pompach P, Dráber P: Down-regulation of protein-tyrosine phosphatases activates an immune receptor in the absence of its translocation into lipid rafts. J Biol Chem; 2010 Apr 23;285(17):12787-802
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  • We found that exposure of rat basophilic leukemia cells or mouse bone marrow-derived mast cells to PTP inhibitors, H(2)O(2) or pervanadate, induced phosphorylation of the Fc epsilonRI subunits, similarly as Fc epsilonRI triggering.

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  • [Cites] J Immunol. 2005 Oct 1;175(7):4543-54 [16177098.001]
  • [Cites] Nat Immunol. 2005 Nov;6(11):1168-76 [16200067.001]
  • [Cites] Nat Rev Immunol. 2006 Mar;6(3):218-30 [16470226.001]
  • [Cites] Mol Pharmacol. 2006 Apr;69(4):1347-55 [16391241.001]
  • [Cites] Physiology (Bethesda). 2006 Dec;21:430-9 [17119156.001]
  • [Cites] Annu Rev Immunol. 2007;25:473-523 [17291189.001]
  • [Cites] J Lipid Res. 2007 Jun;48(6):1325-35 [17387221.001]
  • [Cites] Free Radic Biol Med. 2007 Jul 1;43(1):100-10 [17561098.001]
  • [Cites] Cell Signal. 2007 Nov;19(11):2400-12 [17716862.001]
  • [Cites] J Immunol. 2007 Nov 15;179(10):7059-71 [17982097.001]
  • [Cites] J Cell Biol. 2000 May 29;149(5):1131-42 [10831616.001]
  • [Cites] FEBS Lett. 2000 Jun 16;475(2):121-6 [10858501.001]
  • [Cites] J Biol Chem. 2000 Nov 10;275(45):34976-82 [10956655.001]
  • [Cites] J Struct Biol. 2000 Dec;132(3):201-10 [11243889.001]
  • [Cites] J Cell Biol. 2001 Jan 22;152(2):325-34 [11266449.001]
  • [Cites] Nat Rev Mol Cell Biol. 2000 Oct;1(1):31-9 [11413487.001]
  • [Cites] J Cell Biol. 2001 Aug 6;154(3):645-58 [11489921.001]
  • [Cites] Mol Cell Biol. 2001 Nov;21(21):7117-36 [11585896.001]
  • [Cites] Mol Cell Biol. 2001 Dec;21(24):8318-28 [11713268.001]
  • [Cites] Mol Cell. 2002 Feb;9(2):387-99 [11864611.001]
  • [Cites] Int Arch Allergy Immunol. 2002 Aug;128(4):253-63 [12218363.001]
  • [Cites] Mol Immunol. 2002 Sep;38(16-18):1259-68 [12217393.001]
  • [Cites] J Immunol. 2002 Nov 15;169(10):5866-73 [12421969.001]
  • [Cites] Nat Immunol. 2002 Dec;3(12):1129-34 [12447370.001]
  • [Cites] J Immunol. 2003 Oct 1;171(7):3585-93 [14500655.001]
  • [Cites] Cell. 2003 Nov 14;115(4):377-88 [14622593.001]
  • [Cites] J Immunol. 2003 Dec 1;171(11):6119-27 [14634127.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1886-91 [14762163.001]
  • [Cites] Eur J Immunol. 2004 Jun;34(6):1627-36 [15162432.001]
  • [Cites] Eur J Immunol. 2004 Aug;34(8):2209-19 [15259018.001]
  • [Cites] J Exp Med. 2004 Oct 18;200(8):1001-13 [15477348.001]
  • [Cites] J Immunol Methods. 2007 Dec 1;328(1-2):139-51 [17900607.001]
  • [Cites] ACS Chem Biol. 2007 Oct 19;2(10):674-84 [18041817.001]
  • [Cites] FEBS J. 2008 Jan;275(1):69-88 [18067579.001]
  • [Cites] Annu Rev Immunol. 2008;26:29-55 [18303998.001]
  • [Cites] J Biol Chem. 2008 Sep 12;283(37):25544-56 [18617527.001]
  • [Cites] J Immunol. 2008 Oct 15;181(8):5414-24 [18832698.001]
  • [Cites] Cell. 2009 Jan 23;136(2):352-63 [19167335.001]
  • [Cites] Immunol Rev. 2009 Mar;228(1):149-69 [19290926.001]
  • [Cites] EMBO Rep. 2004 Aug;5(8):812-7 [15247926.001]
  • [Cites] J Immunol. 2000 Feb 1;164(3):1521-8 [10640770.001]
  • [Cites] Exp Cell Res. 1977 Feb;104(2):255-62 [65285.001]
  • [Cites] Proc Natl Acad Sci U S A. 1979 Sep;76(9):4498-502 [291981.001]
  • [Cites] J Immunol. 1980 Jun;124(6):2728-37 [7373045.001]
  • [Cites] Eur J Immunol. 1981 Apr;11(4):317-23 [6166481.001]
  • [Cites] Eur J Immunol. 1981 Jun;11(6):527-9 [6790293.001]
  • [Cites] J Histochem Cytochem. 1988 Sep;36(9):1197-202 [3403970.001]
  • [Cites] Mol Immunol. 1988 Jul;25(7):647-61 [2971137.001]
  • [Cites] J Biol Chem. 1990 Feb 15;265(5):2896-902 [2154464.001]
  • [Cites] Biochemistry. 1990 Nov 6;29(44):10240-5 [2176864.001]
  • [Cites] Nature. 1992 Jan 2;355(6355):78-80 [1370575.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10306-10 [1279675.001]
  • [Cites] Biochem J. 1994 Sep 15;302 ( Pt 3):867-74 [7524478.001]
  • [Cites] Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11246-50 [7526393.001]
  • [Cites] J Biol Chem. 1995 Sep 15;270(37):21902-6 [7545170.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9201-5 [7568101.001]
  • [Cites] Immunology. 1996 Jan;87(1):141-8 [8666426.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7865-70 [8755568.001]
  • [Cites] J Biol Chem. 1997 Jan 10;272(2):843-51 [8995372.001]
  • [Cites] J Biol Chem. 1997 Feb 14;272(7):4276-80 [9020144.001]
  • [Cites] Eur J Immunol. 1997 Jan;27(1):321-8 [9022035.001]
  • [Cites] J Immunol. 1997 Nov 1;159(9):4426-34 [9379041.001]
  • [Cites] J Cell Biol. 1997 Dec 15;139(6):1447-54 [9396750.001]
  • [Cites] Cell. 1998 Jan 9;92(1):83-92 [9489702.001]
  • [Cites] J Mol Biol. 1998 Feb 13;276(1):1-6 [9514733.001]
  • [Cites] J Biol Chem. 1998 Apr 17;273(16):10036-45 [9545350.001]
  • [Cites] Structure. 1998 Mar 15;6(3):249-54 [9551546.001]
  • [Cites] Biochemistry. 1998 Apr 21;37(16):5633-42 [9548949.001]
  • [Cites] J Biol Chem. 1999 Jan 15;274(3):1753-8 [9880557.001]
  • [Cites] J Biol Chem. 2004 Nov 19;279(47):48751-9 [15361524.001]
  • [Cites] Methods. 2005 Jan;35(1):37-43 [15588984.001]
  • [Cites] Arch Biochem Biophys. 2005 Feb 1;434(1):11-5 [15629103.001]
  • [Cites] Cell. 2005 Jun 3;121(5):667-70 [15935753.001]
  • [Cites] Curr Med Chem. 2005;12(16):1859-71 [16101506.001]
  • (PMID = 20157115.001).
  • [ISSN] 1083-351X
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] ENG
  • [Grant] Canada / Canadian Institutes of Health Research / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens; 0 / Enzyme Inhibitors; 0 / Oxidants; 0 / Receptors, IgE; 0 / pervanadate; 3WHH0066W5 / Vanadates; BBX060AN9V / Hydrogen Peroxide; EC 2.7.10.2 / lyn protein-tyrosine kinase; EC 2.7.10.2 / src-Family Kinases; EC 3.1.3.48 / Protein Tyrosine Phosphatases
  • [Other-IDs] NLM/ PMC2857068
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28. Chen HJ, Shih CK, Hsu HY, Chiang W: Mast cell-dependent allergic responses are inhibited by ethanolic extract of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) testa. J Agric Food Chem; 2010 Feb 24;58(4):2596-601
The Lens. Cited by Patents in .

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  • The purpose of this study was to investigate the effects of adlay (Job's tears, Coix lachryma-jobi L. var. ma-yuen Stapf) testa against beta-hexosaminidase release as a marker of degranulation in rat basophilic leukemia (RBL)-2H3 cells.
  • [MeSH-minor] Acetophenones / pharmacology. Animals. Cell Line, Tumor / drug effects. Cell Line, Tumor / immunology. Coumaric Acids / pharmacology. Ethanol. Extracellular Signal-Regulated MAP Kinases / antagonists & inhibitors. Extracellular Signal-Regulated MAP Kinases / drug effects. Leukemia, Basophilic, Acute. Phosphorylation / drug effects. Rats. Signal Transduction / drug effects. Signal Transduction / physiology. beta-N-Acetylhexosaminidases / drug effects. beta-N-Acetylhexosaminidases / secretion

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  • (PMID = 20102206.001).
  • [ISSN] 1520-5118
  • [Journal-full-title] Journal of agricultural and food chemistry
  • [ISO-abbreviation] J. Agric. Food Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acetophenones; 0 / Coumaric Acids; 0 / Plant Extracts; 3K9958V90M / Ethanol; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 3.2.1.52 / beta-N-Acetylhexosaminidases; G1L3HT4CMH / 4-hydroxyacetophenone; IBS9D1EU3J / 4-coumaric acid
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29. Haberman Y, Ziv I, Gorzalczany Y, Hirschberg K, Mittleman L, Fukuda M, Sagi-Eisenberg R: Synaptotagmin (Syt) IX is an essential determinant for protein sorting to secretory granules in mast cells. Blood; 2007 Apr 15;109(8):3385-92
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  • We now show that synaptotagmin (Syt) IX, a Syt homologue that is required for recycling from the endocytic recycling compartment (ERC) in rat basophilic leukemia (RBL-2H3) cultured mast cells, is involved in segregating recycling proteins from the SGs.

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  • (PMID = 17164344.001).
  • [ISSN] 0006-4971
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Protein Complex 1; 0 / Membrane Glycoproteins; 0 / Tgoln2 protein, rat; 134193-27-4 / Synaptotagmins; EC 3.6.5.2 / ADP-Ribosylation Factor 1
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30. Collaco CR, Hochman DJ, Goldblum RM, Brooks EG: Effect of sodium sulfite on mast cell degranulation and oxidant stress. Ann Allergy Asthma Immunol; 2006 Apr;96(4):550-6
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  • OBJECTIVE: To investigate the cellular responses of sulfite on cultured mast cells (rat basophilic leukemia [RBL-2H3] cells) and human peripheral blood basophils.

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  • (PMID = 16680925.001).
  • [ISSN] 1081-1206
  • [Journal-full-title] Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • [ISO-abbreviation] Ann. Allergy Asthma Immunol.
  • [Language] eng
  • [Grant] United States / PHS HHS / / T32-07524
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Reactive Oxygen Species; 0 / Sulfites; 333DO1RDJY / Serotonin; EC 1.6.3.1 / NADPH Oxidase; EC 3.2.1.52 / beta-N-Acetylhexosaminidases; VTK01UQK3G / sodium sulfite
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31. Koumura T, Nakamura C, Nakagawa Y: Role of calcium-induced mitochondrial hydroperoxide in induction of apoptosis of RBL2H3 cells with eicosapentaenoic acid treatment. Free Radic Res; 2005 Oct;39(10):1083-9
Hazardous Substances Data Bank. HYDROGEN PEROXIDE .

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  • Eicosapentaenoic acid (EPA) was previously shown to induce caspase-independent apoptosis in rat basophilic leukemia cells (RBL2H3 cells) by translocation of apoptosis-inducing factor (AIF) [Free Radic Res (2005) 39, 225-235].

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  • (PMID = 16298733.001).
  • [ISSN] 1071-5762
  • [Journal-full-title] Free radical research
  • [ISO-abbreviation] Free Radic. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 11103-72-3 / Ruthenium Red; 139890-68-9 / 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester; 526U7A2651 / Egtazic Acid; 9007-43-6 / Cytochromes c; AAN7QOV9EA / Eicosapentaenoic Acid; BBX060AN9V / Hydrogen Peroxide; EC 1.11.1.12 / phospholipid-hydroperoxide glutathione peroxidase; EC 1.11.1.9 / Glutathione Peroxidase; SY7Q814VUP / Calcium
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32. Semenova SB, Fomina AF, Vassilieva IO, Negulyaev YA: Properties of Mg(2+)-dependent cation channels in human leukemia K562 cells. J Cell Physiol; 2005 Dec;205(3):372-8
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  • [Title] Properties of Mg(2+)-dependent cation channels in human leukemia K562 cells.
  • Here we present a single channel study of endogenously expressed Mg(2+)-dependent cation channels in the human myeloid leukemia K562 cells.
  • The Mg(2+)-dependent cation channels described in this study differ from the MIC channels described in human T-cells, Jurkat, and rat basophilic leukemia (RBL) cells in their I-V relationships, kinetic parameters and dependence on intracellular divalent cations.
  • [MeSH-major] Cations / metabolism. Ion Channels / metabolism. Leukemia, Myeloid / metabolism. Magnesium / metabolism

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  • [Copyright] (c) 2005 Wiley-Liss, Inc.
  • (PMID = 15895364.001).
  • [ISSN] 0021-9541
  • [Journal-full-title] Journal of cellular physiology
  • [ISO-abbreviation] J. Cell. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium Channels; 0 / Cations; 0 / Ion Channels; 0 / RNA, Messenger; 0 / TRPV Cation Channels; 0 / TRPV6 protein, human; I38ZP9992A / Magnesium; SY7Q814VUP / Calcium
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33. Blonski WC, Katzka DA, Lichtenstein GR, Metz DC: Idiopathic gastric acid hypersecretion presenting as a diarrheal disorder and mimicking both Zollinger-Ellison syndrome and Crohn's disease. Eur J Gastroenterol Hepatol; 2005 Apr;17(4):441-4
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  • [Title] Idiopathic gastric acid hypersecretion presenting as a diarrheal disorder and mimicking both Zollinger-Ellison syndrome and Crohn's disease.
  • Many gastric acid hypersecretory states (basal acid output of greater than 15.0 mEq/h) exist for which the etiology is known, such as Zollinger-Ellison syndrome, systemic mastocytosis, antral exclusion, antral predominant Helicobacter pylori gastritis (antral G cell hyperplasia), chronic gastric outlet obstruction, short gut syndrome and basophilic leukemias.

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  • [CommentIn] Eur J Gastroenterol Hepatol. 2005 Dec;17(12):1433 [16292103.001]
  • [CommentIn] Eur J Gastroenterol Hepatol. 2005 Sep;17(9):1001 [16093882.001]
  • (PMID = 15756097.001).
  • [ISSN] 0954-691X
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Ulcer Agents; 0 / Gastrins; KG60484QX9 / Omeprazole
  • [Number-of-references] 28
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34. Tiede LM, Nichols MG: Photobleaching of reduced nicotinamide adenine dinucleotide and the development of highly fluorescent lesions in rat basophilic leukemia cells during multiphoton microscopy. Photochem Photobiol; 2006 May-Jun;82(3):656-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Photobleaching of reduced nicotinamide adenine dinucleotide and the development of highly fluorescent lesions in rat basophilic leukemia cells during multiphoton microscopy.
  • The loss of fluorescence because of multiphoton photobleaching was measured by repetitively imaging individual planes within rat basophilic leukemia cells.
  • [MeSH-major] Leukemia, Basophilic, Acute / pathology. NAD / radiation effects. Photobleaching

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  • (PMID = 16426080.001).
  • [ISSN] 0031-8655
  • [Journal-full-title] Photochemistry and photobiology
  • [ISO-abbreviation] Photochem. Photobiol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / F32 CA 72225; United States / NCRR NIH HHS / RR / RR04224
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0U46U6E8UK / NAD
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35. Harata G, He F, Takahashi K, Hosono A, Kawase M, Kubota A, Hiramatsu M, Kaminogawa S: Bifidobacterium suppresses IgE-mediated degranulation of rat basophilic leukemia (RBL-2H3) cells. Microbiol Immunol; 2010;54(1):54-7

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  • [Title] Bifidobacterium suppresses IgE-mediated degranulation of rat basophilic leukemia (RBL-2H3) cells.
  • Sixteen heat-killed bifidobacteria isolated from human intestine and a probiotic strain Lactobacillus GG were tested for their ability to influence IgE-mediated degranulation of rat basophilic leukemia (RBL-2H3) cells in vitro.
  • [MeSH-major] Basophils / immunology. Bifidobacterium / physiology. Immunoglobulin E / immunology. Leukemia, Basophilic, Acute / immunology
  • [MeSH-minor] Animals. Basophil Degranulation Test. Cell Line, Tumor. Humans. Intestines / microbiology. Lactobacillus / physiology. Rats. Signal Transduction

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  • (PMID = 20055943.001).
  • [ISSN] 0385-5600
  • [Journal-full-title] Microbiology and immunology
  • [ISO-abbreviation] Microbiol. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 37341-29-0 / Immunoglobulin E
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36. Kato N, Nakanishi M, Hirashima N: Flotillin-1 regulates IgE receptor-mediated signaling in rat basophilic leukemia (RBL-2H3) cells. J Immunol; 2006 Jul 1;177(1):147-54
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  • [Title] Flotillin-1 regulates IgE receptor-mediated signaling in rat basophilic leukemia (RBL-2H3) cells.
  • Cross-linking of high-affinity IgE receptors by multivalent Ag on mast cells (rat basophilic leukemia (RBL)-2H3) induces the phosphorylation of ITAM motifs of an IgE receptor by Src family tyrosine kinase, Lyn.
  • We obtained flotillin-1 knockdown (KD)(2) rat basophilic leukemia (RBL)-2H3 cells, which express a low level of flotillin-1.
  • [MeSH-minor] Animals. Calcium / metabolism. Calcium Signaling / physiology. Cell Degranulation / physiology. Cell Line, Tumor. Enzyme Activation / physiology. Extracellular Signal-Regulated MAP Kinases / metabolism. Leukemia, Basophilic, Acute / enzymology. Leukemia, Basophilic, Acute / immunology. Leukemia, Basophilic, Acute / metabolism. Membrane Microdomains / enzymology. Membrane Microdomains / immunology. Membrane Microdomains / metabolism. Phosphorylation. Rats. Transfection. Tyrosine / metabolism. src-Family Kinases / metabolism

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  • (PMID = 16785509.001).
  • [ISSN] 0022-1767
  • [Journal-full-title] Journal of immunology (Baltimore, Md. : 1950)
  • [ISO-abbreviation] J. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Membrane Proteins; 0 / Receptors, IgE; 0 / flotillins; 42HK56048U / Tyrosine; EC 2.7.10.2 / lyn protein-tyrosine kinase; EC 2.7.10.2 / src-Family Kinases; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; SY7Q814VUP / Calcium
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37. Barth EE, Hallworth R, Nichols MG: A comparison of the sensitivity of photodamage assays in rat basophilic leukemia cells. Photochem Photobiol; 2005 May-Jun;81(3):556-62
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  • [Title] A comparison of the sensitivity of photodamage assays in rat basophilic leukemia cells.
  • Photodamage was induced in rat basophilic leukemia cells by either 254-nm UVC light exposure or rose bengal photosensitization.
  • [MeSH-major] Cell Division / radiation effects. Leukemia / pathology. Rose Bengal / toxicity. Ultraviolet Rays / adverse effects

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  • (PMID = 15773792.001).
  • [ISSN] 0031-8655
  • [Journal-full-title] Photochemistry and photobiology
  • [ISO-abbreviation] Photochem. Photobiol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fluoresceins; 0 / Fluorescent Dyes; 0 / Photosensitizing Agents; 1N3CZ14C5O / Rhodamine 123; 1ZPG1ELY14 / Rose Bengal; 36015-30-2 / Propidium; EC 3.1.- / Esterases; G34N38R2N1 / Bromodeoxyuridine; V0YM2B16TS / fluorexon
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38. Pidala J, Pinilla-Ibarz J, Cualing HD: A case of acute basophilic leukemia arising from chronic myelogenous leukemia with development of t(7;8)(q32;q13). Cancer Genet Cytogenet; 2008 Apr 1;182(1):46-9
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  • [Title] A case of acute basophilic leukemia arising from chronic myelogenous leukemia with development of t(7;8)(q32;q13).
  • Acute basophilic leukemia (ABL) is an uncommon form of acute myelogenous leukemia recently recognized as a distinct entity in the World Health Organization classification of myeloid malignancies.
  • A case is presented of ABL arising from chronic myelogenous leukemia with development of t(7;8)(q32;q13).
  • [MeSH-major] Chromosomes, Human, Pair 7. Chromosomes, Human, Pair 8. Leukemia, Basophilic, Acute / genetics. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications. Translocation, Genetic


39. Kokandakar HR, Tembhare PR, Mamoon A, Mulay VM, Bhople KS: Acute basophilic leukaemia: a case report. Indian J Pathol Microbiol; 2007 Apr;50(2):443-6

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  • [Title] Acute basophilic leukaemia: a case report.
  • Acute basophilic leukaemia is an uncommon form of acute leukaemia, rarely occurring as de novo disease.
  • We present a case of acute basophilic leukaemia with (11q23)-MLL gene rearrangement, in an 18-year-old male with review of literature and discussion of diagnostic criteria.
  • [MeSH-major] Leukemia, Basophilic, Acute / diagnosis
  • [MeSH-minor] Adolescent. Coloring Agents. Gene Rearrangement. Histone-Lysine N-Methyltransferase. Humans. Male. Myeloid-Lymphoid Leukemia Protein / genetics. Staining and Labeling. Tolonium Chloride

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  • (PMID = 17883105.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / MLL protein, human; 149025-06-9 / Myeloid-Lymphoid Leukemia Protein; 15XUH0X66N / Tolonium Chloride; EC 2.1.1.43 / Histone-Lysine N-Methyltransferase
  • [Number-of-references] 11
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40. Yanase Y, Hiragun T, Kaneko S, Gould HJ, Greaves MW, Hide M: Detection of refractive index changes in individual living cells by means of surface plasmon resonance imaging. Biosens Bioelectron; 2010 Oct 15;26(2):674-81

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  • The SPRI sensor could detect reactions of individual rat basophilic leukemia (RBL-2H3) cells, mouse keratinocyte (PAM212) cells, and human epidermal carcinoma (A431) cells in response to either specific or non-specific stimuli, such as antigen, phorbol ester or epidermal growth factor, with or without their inhibitors, resembling signals obtained by a conventional SPR sensor.

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  • [Copyright] Copyright © 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20673712.001).
  • [ISSN] 1873-4235
  • [Journal-full-title] Biosensors & bioelectronics
  • [ISO-abbreviation] Biosens Bioelectron
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0501494
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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41. Ferreres F, Pereira DM, Gil-Izquierdo A, Valentão P, Botelho J, Mouga T, Andrade PB: HPLC-PAD-atmospheric pressure chemical ionization-MS metabolite profiling of cytotoxic carotenoids from the echinoderm Marthasterias glacialis (spiny sea-star). J Sep Sci; 2010 Aug;33(15):2250-7
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  • The purified carotenoid fraction displayed a strong cell proliferation inhibition against rat basophilic leukemia RBL-2H3 (IC(25)=268 microg/mL) cancer cell line.

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  • (PMID = 20574958.001).
  • [ISSN] 1615-9314
  • [Journal-full-title] Journal of separation science
  • [ISO-abbreviation] J Sep Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 36-88-4 / Carotenoids
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42. Tanifuji S, Aizu-Yokota E, Funakoshi-Tago M, Sonoda Y, Inoue H, Kasahara T: Licochalcones suppress degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells. Int Immunopharmacol; 2010 Jul;10(7):769-76
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  • We examined the effects of Lico A and related chalcones on degranulation in a rat basophilic leukemia cell line, RBL-2H3.

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  • [Copyright] 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20399908.001).
  • [ISSN] 1878-1705
  • [Journal-full-title] International immunopharmacology
  • [ISO-abbreviation] Int. Immunopharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Chalcones; 42HK56048U / Tyrosine; 58749-22-7 / licochalcone A; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; SY7Q814VUP / Calcium
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43. Yamada P, Iijima R, Han J, Shigemori H, Yokota S, Isoda H: Inhibitory effect of acteoside isolated from Cistanche tubulosa on chemical mediator release and inflammatory cytokine production by RBL-2H3 and KU812 cells. Planta Med; 2010 Oct;76(14):1512-8
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  • Wight on the basophilic cell-mediated allergic reaction.
  • The effect of acteoside on β-hexosaminidase release and intracellular [Ca (2+)] I level from rat basophilic leukemia (RBL-2H3) cells was determined.
  • Also, ELISA was used to determine the level of histamine, tumor necrosis factor (TNF)- α, and interleukin (IL)-4 on human basophilic (KU812) cells.
  • The effect of acteoside on basophilic cell viability was determined using the 3-[4,5-dimethylthiazolyl]-2,5-diphenyltetrazolium bromide (MTT) assay.
  • Our findings provide evidence that acteoside inhibits basophilic cell-derived immediate-type and delayed-type allergic reactions.
  • This is the first report describing antiallergic activity of acteoside extracted from CISTANCHE TUBULOSA on basophilic cells.

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  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 20354949.001).
  • [ISSN] 1439-0221
  • [Journal-full-title] Planta medica
  • [ISO-abbreviation] Planta Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anti-Allergic Agents; 0 / Catechols; 0 / Glucosides; 0 / Glycosides; 0 / IL4 protein, human; 0 / Phenols; 0 / Tumor Necrosis Factor-alpha; 0 / cistanoside A; 207137-56-2 / Interleukin-4; 37H9VM9WZL / Calcimycin; 61276-17-3 / acteoside; 820484N8I3 / Histamine; 82854-37-3 / echinacoside; EC 3.2.1.52 / beta-N-Acetylhexosaminidases; NI40JAQ945 / Tetradecanoylphorbol Acetate; SY7Q814VUP / Calcium
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44. Kaneko M, Kanesaka M, Yoneyama M, Tominaga T, Jirillo E, Kumazawa Y: Inhibitory effects of fermented grape marc from Vitis vinifera Negroamaro on antigen-induced degranulation. Immunopharmacol Immunotoxicol; 2010 Sep;32(3):454-61
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  • To investigate the antiallergic effects of fermented grape marc from Negroamaro (N-FGM), we examined antigen (Ag)-induced degranulation of rat basophilic leukemia (RBL-2H3) cells.
  • [MeSH-minor] Animals. Antigens / immunology. Basophil Degranulation Test. Fermentation. Immunoglobulin E / immunology. Intracellular Signaling Peptides and Proteins / metabolism. Phosphorylation. Protein-Tyrosine Kinases / metabolism. Rats. Syk Kinase. Tumor Cells, Cultured

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  • (PMID = 20100066.001).
  • [ISSN] 1532-2513
  • [Journal-full-title] Immunopharmacology and immunotoxicology
  • [ISO-abbreviation] Immunopharmacol Immunotoxicol
  • [Language] eng
  • [Grant] United Kingdom / Biotechnology and Biological Sciences Research Council / / BB/D008123/1
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Allergic Agents; 0 / Antigens; 0 / Intracellular Signaling Peptides and Proteins; 37341-29-0 / Immunoglobulin E; 9IKM0I5T1E / Quercetin; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.2 / Syk Kinase; EC 2.7.10.2 / Syk protein, rat
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45. Gadermaier G, Jahn-Schmid B, Vogel L, Egger M, Himly M, Briza P, Ebner C, Vieths S, Bohle B, Ferreira F: Targeting the cysteine-stabilized fold of Art v 1 for immunotherapy of Artemisia pollen allergy. Mol Immunol; 2010 Mar;47(6):1292-8
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  • Mediator release assays using rat basophil leukemia cells showed that these variants displayed a 1x10(5)-fold reduced allergenic potency as compared to wild-type protein.

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  • [Copyright] Copyright 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 20022115.001).
  • [ISSN] 1872-9142
  • [Journal-full-title] Molecular immunology
  • [ISO-abbreviation] Mol. Immunol.
  • [Language] eng
  • [Grant] Austria / Austrian Science Fund FWF / / P 20011
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Allergens; 0 / Antibodies; 0 / Antigens, Plant; 0 / Art v 1 protein, mugwort; 0 / Mutant Proteins; 0 / Plant Proteins; 37341-29-0 / Immunoglobulin E; K848JZ4886 / Cysteine
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46. Cohen R, Torres A, Ma HT, Holowka D, Baird B: Ca2+ waves initiate antigen-stimulated Ca2+ responses in mast cells. J Immunol; 2009 Nov 15;183(10):6478-88
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  • Using single cell stimulation by IgE-specific Ag and high-speed imaging of conventional or genetically encoded Ca(2+) sensors in rat basophilic leukemia and bone marrow-derived rat mast cells, we observe Ca(2+) waves that originate most frequently from the tips of extended cell protrusions, as well as Ca(2+) oscillations throughout the cell that usually follow the initiating Ca(2+) wave.
  • Initiating Ca(2+) waves are observed in most rat basophilic leukemia cells stimulated with soluble Ag and are sensitive to inhibitors of Ca(2+) release from endoplasmic reticulum stores and to extracellular Ca(2+), but they do not depend on store-operated Ca(2+) entry.

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  • [Cites] J Allergy Clin Immunol. 2006 Jun;117(6):1214-25; quiz 1226 [16750977.001]
  • [Cites] Science. 2006 Jul 14;313(5784):229-33 [16840702.001]
  • [Cites] Cell Calcium. 2006 Nov-Dec;40(5-6):405-12 [17030366.001]
  • [Cites] J Physiol. 2007 Jan 1;578(Pt 1):55-67 [17038427.001]
  • [Cites] Cell Calcium. 2007 Jun;41(6):525-36 [17324458.001]
  • [Cites] Cell Calcium. 2007 Aug;42(2):111-21 [17445883.001]
  • [Cites] Gastroenterology. 2007 Jul;133(1):256-67 [17631147.001]
  • [Cites] Cell Calcium. 2007 Sep;42(3):333-9 [17343911.001]
  • [Cites] Cell. 2007 Dec 14;131(6):1047-58 [18083096.001]
  • [Cites] J Immunol. 2008 Feb 15;180(4):2233-9 [18250430.001]
  • [Cites] Biochem Pharmacol. 2008 Apr 1;75(7):1492-503 [18243160.001]
  • [Cites] Nat Rev Immunol. 2008 Jun;8(6):478-86 [18483499.001]
  • [Cites] Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17238-44 [19004813.001]
  • [Cites] J Biol Chem. 1999 Nov 26;274(48):34272-6 [10567402.001]
  • [Cites] Cell Calcium. 1999 Dec;26(6):261-9 [10668564.001]
  • [Cites] J Physiol. 2001 Feb 1;530(Pt 3):417-29 [11158273.001]
  • [Cites] EMBO J. 2001 Jan 15;20(1-2):65-76 [11226156.001]
  • [Cites] J Physiol. 2001 Apr 1;532(Pt 1):55-71 [11283225.001]
  • [Cites] J Biol Chem. 2001 May 11;276(19):15945-52 [11278938.001]
  • [Cites] J Cell Sci. 2001 Jun;114(Pt 12):2213-22 [11493661.001]
  • [Cites] Am J Physiol. 1998 Sep;275(3 Pt 1):C848-56 [9730970.001]
  • [Cites] J Biol Chem. 1998 Sep 25;273(39):25020-30 [9737958.001]
  • [Cites] Trends Pharmacol Sci. 1998 Sep;19(9):370-5 [9786025.001]
  • [Cites] Arch Dermatol Res. 1999 Jun;291(6):318-24 [10421057.001]
  • [Cites] EMBO J. 1999 Oct 1;18(19):5285-99 [10508162.001]
  • [Cites] Mol Cell. 1999 Sep;4(3):423-9 [10518223.001]
  • [Cites] J Biol Chem. 1999 Oct 22;274(43):30784-93 [10521469.001]
  • [Cites] Biochim Biophys Acta. 2004 Dec 6;1742(1-3):3-7 [15590051.001]
  • [Cites] Nature. 2005 Mar 3;434(7029):99-104 [15744307.001]
  • [Cites] J Physiol. 2001 Oct 1;536(Pt 1):3-19 [11579153.001]
  • [Cites] J Neurochem. 2001 Oct;79(1):98-109 [11595762.001]
  • [Cites] Trends Pharmacol Sci. 2001 Nov;22(11):580-6 [11698102.001]
  • [Cites] J Cell Sci. 2001 Nov;114(Pt 22):3979-89 [11739630.001]
  • [Cites] Receptors Channels. 2001;7(6):429-39 [11918346.001]
  • [Cites] Cell Calcium. 2002 Oct;32(4):217-29 [12379182.001]
  • [Cites] J Immunol. 2002 Dec 15;169(12):6743-52 [12471105.001]
  • [Cites] J Immunol. 2003 Jan 1;170(1):64-72 [12496384.001]
  • [Cites] Cell Calcium. 2003 Aug;34(2):131-44 [12810055.001]
  • [Cites] Eur J Clin Invest. 2003 Jul;33(7):601-10 [12814398.001]
  • [Cites] J Biol Chem. 2003 Jul 25;278(30):27540-7 [12746430.001]
  • [Cites] J Exp Med. 2004 Apr 5;199(7):959-70 [15067032.001]
  • [Cites] Acta Pathol Microbiol Scand. 1966;66(3):303-12 [4162018.001]
  • [Cites] Proc Natl Acad Sci U S A. 1977 Feb;74(2):623-7 [322135.001]
  • [Cites] Eur J Immunol. 1981 Apr;11(4):317-23 [6166481.001]
  • [Cites] Proc Natl Acad Sci U S A. 1985 Jun;82(11):3871-5 [3923482.001]
  • [Cites] J Biol Chem. 1986 Sep 5;261(25):11823-31 [2943732.001]
  • [Cites] Proc Natl Acad Sci U S A. 1988 Mar;85(6):1854-8 [3162312.001]
  • [Cites] J Biol Chem. 1989 Aug 5;264(22):13267-72 [2526814.001]
  • [Cites] J Biol Chem. 1990 Jan 15;265(2):678-84 [2404009.001]
  • [Cites] Cell Calcium. 1990 Feb-Mar;11(2-3):145-55 [2141302.001]
  • [Cites] Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9883-7 [1946414.001]
  • [Cites] Nature. 1992 Jan 23;355(6358):353-6 [1309940.001]
  • [Cites] Proc Biol Sci. 1991 Dec 23;246(1317):269-74 [1686093.001]
  • [Cites] Biochemistry. 1992 Jun 16;31(23):5350-6 [1534998.001]
  • [Cites] Blood. 1994 Jan 1;83(1):72-83 [7506083.001]
  • [Cites] Ital J Anat Embryol. 1993 Oct-Dec;98(4):243-58 [8018016.001]
  • [Cites] J Immunol. 1995 Mar 1;154(5):2393-402 [7532669.001]
  • [Cites] J Biol Chem. 1995 Apr 7;270(14):8102-7 [7713913.001]
  • [Cites] J Physiol. 1995 Feb 1;482 ( Pt 3):533-53 [7738847.001]
  • [Cites] Mol Biol Cell. 1995 Jul;6(7):825-39 [7579697.001]
  • [Cites] Hear Res. 1995 Aug;88(1-2):36-46 [8576001.001]
  • [Cites] J Cell Biol. 1996 Sep;134(6):1427-39 [8830772.001]
  • [Cites] FASEB J. 1996 Nov;10(13):1505-17 [8940296.001]
  • [Cites] J Physiol. 1997 Mar 1;499 ( Pt 2):291-306 [9080360.001]
  • [Cites] J Immunol. 1997 Apr 15;158(8):3805-12 [9103447.001]
  • [Cites] J Biochem. 1997 Sep;122(3):498-505 [9348075.001]
  • [Cites] Physiol Rev. 1997 Oct;77(4):1033-79 [9354811.001]
  • [Cites] Cell. 1997 Oct 31;91(3):367-73 [9363945.001]
  • [Cites] J Biol Chem. 1997 Dec 12;272(50):31225-9 [9395446.001]
  • [Cites] Immunology. 1998 Apr;93(4):533-9 [9659226.001]
  • [Cites] J Immunol. 2009 Feb 1;182(3):1770 [19155527.001]
  • [Cites] Crit Rev Immunol. 2009;29(2):155-86 [19496745.001]
  • [Cites] Mol Biol Cell. 2009 Jan;20(1):389-99 [18987344.001]
  • [Cites] Blood. 2005 Jun 1;105(11):4282-9 [15718418.001]
  • [Cites] J Immunol. 2005 Aug 15;175(4):2123-31 [16081778.001]
  • [Cites] Cell Calcium. 2005 Dec;38(6):581-92 [16219349.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4753-8 [16537386.001]
  • (PMID = 19864608.001).
  • [ISSN] 1550-6606
  • [Journal-full-title] Journal of immunology (Baltimore, Md. : 1950)
  • [ISO-abbreviation] J. Immunol.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI022449; United States / NIAID NIH HHS / AI / R01 AI022449-23; United States / NIAID NIH HHS / AI / AI022449
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium Channel Blockers; 0 / Estrenes; 0 / Phosphodiesterase Inhibitors; 0 / Pyrrolidinones; 0 / TRPC Cation Channels; 0 / TRPC3 cation channel; 0 / transient receptor potential cation channel, subfamily C, member 1; 112648-68-7 / 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione; 37341-29-0 / Immunoglobulin E; I9ZF7L6G2L / Nifedipine; NGZ37HRE42 / Sphingosine; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ NIHMS265600; NLM/ PMC3037335
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47. Schulmeister U, Hochwallner H, Swoboda I, Focke-Tejkl M, Geller B, Nystrand M, Härlin A, Thalhamer J, Scheiblhofer S, Keller W, Niggemann B, Quirce S, Ebner C, Mari A, Pauli G, Herz U, Valenta R, Spitzauer S: Cloning, expression, and mapping of allergenic determinants of alphaS1-casein, a major cow's milk allergen. J Immunol; 2009 Jun 1;182(11):7019-29
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  • The allergenic activity of ralphaS1-casein and the alphaS1-casein-derived peptides was determined using rat basophil leukemia cells transfected with human FcepsilonRI, which had been loaded with the patients' serum IgE.
  • Our results demonstrate that ralphaS1-casein as well as alphaS1-casein-derived peptides exhibit IgE reactivity, but mainly the intact ralphaS1-casein induced strong basophil degranulation.

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  • (PMID = 19454699.001).
  • [ISSN] 1550-6606
  • [Journal-full-title] Journal of immunology (Baltimore, Md. : 1950)
  • [ISO-abbreviation] J. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Allergens; 0 / Caseins; 0 / DNA, Complementary; 0 / Epitopes; 0 / Peptide Fragments; 0 / Receptors, IgE; 37341-29-0 / Immunoglobulin E
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48. Lim H, Son KH, Bae KH, Hung TM, Kim YS, Kim HP: 5-lipoxygenase-inhibitory constituents from Schizandra fructus and Magnolia flos. Phytother Res; 2009 Oct;23(10):1489-92
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  • The compounds including schizandrins, schisandrols, gomisins, fargesin, eudesmin and lirioresinol B dimethyl ether, inhibited 5-LOX-catalysed leukotriene production from A23187-treated rat basophilic leukemia (RBL-1) cells at concentrations of 1-100 microm.

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  • [Copyright] (c) 2009 John Wiley & Sons, Ltd.
  • (PMID = 19277963.001).
  • [ISSN] 1099-1573
  • [Journal-full-title] Phytotherapy research : PTR
  • [ISO-abbreviation] Phytother Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Allergic Agents; 0 / Cyclooctanes; 0 / Leukotrienes; 0 / Lignans; 0 / Lipoxygenase Inhibitors; 0 / Plant Extracts; 0 / schisandrol A; 31C4KY9ESH / Nitric Oxide; EC 1.14.13.39 / Nitric Oxide Synthase Type II; EC 1.14.99.1 / Cyclooxygenase 2; K7Q1JQR04M / Dinoprostone
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49. Muik M, Fahrner M, Derler I, Schindl R, Bergsmann J, Frischauf I, Groschner K, Romanin C: A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels. J Biol Chem; 2009 Mar 27;284(13):8421-6
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  • Expressing OASF in rat basophilic leukemia (RBL) mast cells demonstrated its enhanced plasma membrane targeting associated with 2.5-fold larger CRAC currents in comparison with the complete STIM1 C terminus.

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  • [Cites] Biophys J. 2001 Oct;81(4):2395-402 [11566809.001]
  • [Cites] Curr Biol. 2007 May 1;17(9):794-800 [17442569.001]
  • [Cites] Cell Calcium. 2003 May-Jun;33(5-6):311-21 [12765678.001]
  • [Cites] Biophys J. 2003 Jun;84(6):3992-4010 [12770904.001]
  • [Cites] Nat Rev Mol Cell Biol. 2003 Jul;4(7):517-29 [12838335.001]
  • [Cites] Annu Rev Physiol. 1990;52:415-30 [1691906.001]
  • [Cites] Nature. 1992 Jan 23;355(6358):353-6 [1309940.001]
  • [Cites] Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6295-9 [8392195.001]
  • [Cites] Biochem J. 1999 Aug 15;342 ( Pt 1):119-23 [10432308.001]
  • [Cites] Physiol Rev. 2005 Apr;85(2):757-810 [15788710.001]
  • [Cites] J Cell Biol. 2005 May 9;169(3):435-45 [15866891.001]
  • [Cites] Curr Biol. 2005 Jul 12;15(13):1235-41 [16005298.001]
  • [Cites] Nature. 2006 May 11;441(7090):179-85 [16582901.001]
  • [Cites] Science. 2006 May 26;312(5777):1220-3 [16645049.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9357-62 [16751269.001]
  • [Cites] J Biol Chem. 2006 Aug 25;281(34):24979-90 [16807233.001]
  • [Cites] Nat Neurosci. 2006 Sep;9(9):1108-16 [16921373.001]
  • [Cites] Nat Cell Biol. 2006 Sep;8(9):1003-10 [16906149.001]
  • [Cites] J Cell Biol. 2006 Sep 11;174(6):803-13 [16966422.001]
  • [Cites] J Cell Biol. 2006 Sep 11;174(6):815-25 [16966423.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16704-9 [17075073.001]
  • [Cites] J Physiol. 2006 Nov 15;577(Pt 1):31-44 [16959851.001]
  • [Cites] J Biol Chem. 2006 Nov 24;281(47):35855-62 [17020874.001]
  • [Cites] Biochem J. 2007 Jul 15;405(2):199-221 [17590154.001]
  • [Cites] Cell Calcium. 2007 Aug;42(2):123-32 [17382385.001]
  • [Cites] J Gen Physiol. 2007 Nov;130(5):525-40 [17968026.001]
  • [Cites] J Biol Chem. 2008 Mar 21;283(12):8014-22 [18187424.001]
  • [Cites] Biochem Biophys Res Commun. 2008 Apr 25;369(1):240-6 [18166150.001]
  • [Cites] J Biol Chem. 2008 Jun 20;283(25):17662-71 [18420579.001]
  • [Cites] Mol Biol Cell. 2008 Jul;19(7):2802-17 [18448669.001]
  • [Cites] Nature. 2008 Jul 24;454(7203):538-42 [18596693.001]
  • [Cites] Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13668-73 [18757751.001]
  • [Cites] Channels (Austin). 2008 Jul-Aug;2(4):261-8 [18769136.001]
  • [Cites] J Cell Sci. 2008 Oct 1;121(Pt 19):3133-9 [18765567.001]
  • [Cites] Nature. 2008 Nov 6;456(7218):116-20 [18820677.001]
  • [Cites] Mol Cell. 2008 Nov 7;32(3):439-48 [18995841.001]
  • [Cites] J Physiol. 2008 Nov 15;586(Pt 22):5383-401 [18832420.001]
  • [Cites] Cell. 2003 Feb 21;112(4):441-51 [12600309.001]
  • (PMID = 19189966.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ P18169/ P18280/ P21118
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium Channels; 0 / Membrane Glycoproteins; 0 / Membrane Proteins; 0 / Neoplasm Proteins; 0 / ORAI1 protein, human; 0 / Orai1 protein, rat; 0 / STIM1 protein, human; 0 / Stim1 protein, rat; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ PMC2659200
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50. Torres AJ, Vasudevan L, Holowka D, Baird BA: Focal adhesion proteins connect IgE receptors to the cytoskeleton as revealed by micropatterned ligand arrays. Proc Natl Acad Sci U S A; 2008 Nov 11;105(45):17238-44
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

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  • Patterned surfaces that present specific ligands in spatially defined arrays are used to examine structural linkages between clustered IgE receptors (IgE-Fc epsilonRI) and the cytoskeleton in rat basophilic leukemia (RBL) mast cells.
  • Significantly, the most prominent rat basophilic leukemia cell integrin (alpha5) avoids the patterned regions occupied by the ligands and associates preferentially with exposed regions of the silicon substrate.

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  • [Cites] Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13798-803 [15356342.001]
  • [Cites] Biosens Bioelectron. 2004 Nov 1;20(4):791-6 [15522594.001]
  • [Cites] Biochim Biophys Acta. 2005 Dec 30;1746(3):252-9 [16054713.001]
  • [Cites] Trends Cell Biol. 2006 Sep;16(9):453-60 [16893648.001]
  • [Cites] Biochem J. 2007 Apr 15;403(2):275-81 [17233630.001]
  • [Cites] J Biol Chem. 2007 Sep 14;282(37):27181-91 [17640867.001]
  • [Cites] J Cell Biol. 2007 Nov 19;179(4):733-46 [18025306.001]
  • [Cites] Semin Cancer Biol. 2008 Feb;18(1):65-76 [18023204.001]
  • [Cites] Annu Rev Biophys. 2008;37:265-88 [18573082.001]
  • [Cites] Immunology. 1999 Oct;98(2):253-7 [10540224.001]
  • [Cites] Curr Opin Cell Biol. 2000 Feb;12(1):133-9 [10679361.001]
  • [Cites] J Cell Sci. 2000 Mar;113 ( Pt 6):1009-19 [10683149.001]
  • [Cites] J Biomed Mater Res. 2001 Jun 15;55(4):487-95 [11288076.001]
  • [Cites] Int Arch Allergy Immunol. 2001 Jun;125(2):152-9 [11435732.001]
  • [Cites] Br J Pharmacol. 2002 Jul;136(6):837-46 [12110608.001]
  • [Cites] Nat Rev Mol Cell Biol. 2002 Aug;3(8):586-99 [12154370.001]
  • [Cites] Bioorg Med Chem Lett. 2003 Sep 15;13(18):3111-4 [12941345.001]
  • [Cites] J Exp Med. 2004 Jun 7;199(11):1491-502 [15173205.001]
  • [Cites] Mol Immunol. 2004 Jul;41(8):817-29 [15234561.001]
  • [Cites] Physiol Rev. 2004 Oct;84(4):1315-39 [15383653.001]
  • [Cites] J Immunol. 1992 Jul 15;149(2):615-21 [1378072.001]
  • [Cites] Mol Immunol. 1994 May;31(7):519-29 [8190127.001]
  • [Cites] J Allergy Clin Immunol. 1994 Sep;94(3 Pt 2):625-8 [8083471.001]
  • [Cites] J Immunol. 1994 Nov 15;153(10):4655-62 [7963537.001]
  • [Cites] J Physiol Pharmacol. 1994 Dec;45(4):501-16 [7537125.001]
  • [Cites] Biochemistry. 1996 Apr 30;35(17):5518-27 [8611543.001]
  • [Cites] J Cell Biol. 1996 Sep;134(6):1427-39 [8830772.001]
  • [Cites] Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1919-24 [9050880.001]
  • [Cites] Biochemistry. 1997 Jun 17;36(24):7447-56 [9200693.001]
  • [Cites] J Biol Chem. 1997 Oct 10;272(41):25753-60 [9325302.001]
  • [Cites] J Immunol. 1999 Feb 15;162(4):2243-50 [9973500.001]
  • [Cites] J Cell Biol. 1999 May 17;145(4):877-87 [10330413.001]
  • [Cites] Annu Rev Immunol. 1999;17:931-72 [10358778.001]
  • [Cites] J Cell Biol. 1988 Mar;106(3):925-30 [2450101.001]
  • (PMID = 19004813.001).
  • [ISSN] 1091-6490
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI018306; United States / NIAID NIH HHS / AI / AI18306
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Ligands; 0 / Paxillin; 0 / RNA, Small Interfering; 0 / Receptors, IgE; 0 / Talin; 125361-02-6 / Vinculin; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ PMC2582307
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51. Jensen BM, Swindle EJ, Iwaki S, Gilfillan AM: Generation, isolation, and maintenance of rodent mast cells and mast cell lines. Curr Protoc Immunol; 2006 Sep;Chapter 3:Unit 3.23
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  • In addition to human mast cells, the major cell culture systems employed to investigate these responses are rat and mouse peritoneal mast cells, mouse bone-marrow-derived mast cells, the rat basophilic leukemia cell line RBL-2H3, and the mouse MC/9 mast cell line.

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  • (PMID = 18432974.001).
  • [ISSN] 1934-368X
  • [Journal-full-title] Current protocols in immunology
  • [ISO-abbreviation] Curr Protoc Immunol
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / ZIA AI000965-04; United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, IgE
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52. Leung WH, Bolland S: The inositol 5'-phosphatase SHIP-2 negatively regulates IgE-induced mast cell degranulation and cytokine production. J Immunol; 2007 Jul 1;179(1):95-102
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  • Coimmunoprecipitation experiments in rat basophilic leukemia (RBL 2H3) cells show that SHIP-2 interacts with the FcepsilonRI beta-chain, Gab2 and Lyn and that unlike SHIP-1, it does not associate with SHC in mast cells.


53. Zhu CB, Steiner JA, Munn JL, Daws LC, Hewlett WA, Blakely RD: Rapid stimulation of presynaptic serotonin transport by A(3) adenosine receptors. J Pharmacol Exp Ther; 2007 Jul;322(1):332-40
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  • Using rat basophilic leukemia 2H3 cell line (RBL-2H3), we previously established that activation of A(3) adenosine receptors (A(3)AR) stimulates SERT activity via both PKG and p38 MAPK (Zhu et al., 2004a).

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  • (PMID = 17460150.001).
  • [ISSN] 0022-3565
  • [Journal-full-title] The Journal of pharmacology and experimental therapeutics
  • [ISO-abbreviation] J. Pharmacol. Exp. Ther.
  • [Language] eng
  • [Grant] United States / NIDA NIH HHS / DA / DA07390
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptor, Adenosine A3; 0 / Serotonin Plasma Membrane Transport Proteins; 152918-18-8 / N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine; 20125-40-0 / N-(1-methyl-2-phenylethyl)adenosine; 333DO1RDJY / Serotonin; 35920-39-9 / Adenosine-5'-(N-ethylcarboxamide); EC 2.7.11.12 / Cyclic GMP-Dependent Protein Kinases; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases; K72T3FS567 / Adenosine
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54. Lessmann E, Leitges M, Huber M: A redundant role for PKC-epsilon in mast cell signaling and effector function. Int Immunol; 2006 May;18(5):767-73
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  • A critical role of PKC-epsilon in antigen-triggered activation of various signaling pathways was observed in basophilic leukemia cells.


55. Rettig JR, Folch A: Large-scale single-cell trapping and imaging using microwell arrays. Anal Chem; 2005 Sep 1;77(17):5628-34
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  • We have characterized microwell occupancy by cells for a range of microwell dimensions and seeding parameters and optimized it for fibroblasts (as a model of adherent cell) and rat basophilic leukemia cells (as a model of nonadherent cell).

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  • (PMID = 16131075.001).
  • [ISSN] 0003-2700
  • [Journal-full-title] Analytical chemistry
  • [ISO-abbreviation] Anal. Chem.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / R21DC006465
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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56. Källquist L, Rosén H, Nordenfelt P, Calafat J, Janssen H, Persson AM, Hansson M, Olsson I: Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells. Exp Cell Res; 2010 Nov 15;316(19):3182-96
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  • The NE aminoacid residue Y199 of a proposed NE sorting motif that interacts with AP-3 [2] was not required for proNE processing, sorting or endocytosis in rat basophilic leukemia (RBL) cells expressing heterologous Y199-deleted proNE; this suggests operation of another AP-3-link for proNE targeting.

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20828556.001).
  • [ISSN] 1090-2422
  • [Journal-full-title] Experimental cell research
  • [ISO-abbreviation] Exp. Cell Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Protein Complex 3; 0 / Antigens, CD; 0 / Antigens, CD63; 0 / CD63 protein, human; 0 / Cd63 protein, rat; 0 / Enzyme Precursors; 0 / Platelet Membrane Glycoproteins; 42HK56048U / Tyrosine; EC 3.4.21.37 / Leukocyte Elastase; EC 3.4.21.76 / Myeloblastin; EC 5.2.1.- / Tacrolimus Binding Proteins
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57. Nakamura R, Nakamura R, Watanabe K, Oka K, Ohta S, Mishima S, Teshima R: Effects of propolis from different areas on mast cell degranulation and identification of the effective components in propolis. Int Immunopharmacol; 2010 Sep;10(9):1107-12
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  • The amount of released beta-hexosaminidase via high-affinity IgE receptor I (Fc epsilon RI) from rat basophilic leukemia (RBL-2H3) cells was used as an index of degranulation.

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  • [Copyright] (c) 2010 Elsevier B.V. All rights reserved.
  • [CommentIn] Int Immunopharmacol. 2011 Sep;11(9):1386-7 [21481329.001]
  • (PMID = 20601180.001).
  • [ISSN] 1878-1705
  • [Journal-full-title] International immunopharmacology
  • [ISO-abbreviation] Int. Immunopharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Allergic Agents; 0 / Chemokine CCL2; 0 / Cytokines; 0 / Flavonoids; 0 / Kaempferols; 0 / Plant Extracts; 0 / Receptors, IgE; 207137-56-2 / Interleukin-4; 3CN01F5ZJ5 / chrysin; 731P2LE49E / kaempferol; 9009-62-5 / Propolis; EC 3.2.1.52 / beta-N-Acetylhexosaminidases
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58. Huelsenbeck SC, Klose I, Reichenbach M, Huelsenbeck J, Genth H: Distinct kinetics of (H/K/N)Ras glucosylation and Rac1 glucosylation catalysed by Clostridium sordellii lethal toxin. FEBS Lett; 2009 Oct 6;583(19):3133-9
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  • Alternative Ras antibodies including the K-Ras(Mab F234) antibody or the v-H-Ras(Mab Y13-159) antibody recognize Ras proteins regardless of glucosylation. (H/K)Ras are further shown to be more efficaciously glucosylated by TcsL than Rac1 in rat basophilic leukemia cells as well as in a cell-free system.

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  • (PMID = 19744486.001).
  • [ISSN] 1873-3468
  • [Journal-full-title] FEBS letters
  • [ISO-abbreviation] FEBS Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies; 0 / Bacterial Toxins; 0 / lethal toxin LT, Clostridium sordellii; EC 3.6.5.2 / rac1 GTP-Binding Protein; EC 3.6.5.2 / ras Proteins
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59. Sakai S, Sugawara T, Matsubara K, Hirata T: Inhibitory effect of carotenoids on the degranulation of mast cells via suppression of antigen-induced aggregation of high affinity IgE receptors. J Biol Chem; 2009 Oct 9;284(41):28172-9
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  • Fucoxanthin, astaxanthin, zeaxanthin, and beta-carotene significantly inhibited the antigen-induced release of beta-hexosaminidase in rat basophilic leukemia 2H3 cells and mouse bone marrow-derived mast cells.

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  • [Cites] Nat Rev Immunol. 2006 Mar;6(3):218-30 [16470226.001]
  • [Cites] Biosci Biotechnol Biochem. 2007 Apr;71(4):1069-72 [17420600.001]
  • [Cites] Blood. 2000 Mar 1;95(5):1752-7 [10688834.001]
  • [Cites] J Histochem Cytochem. 2000 Dec;48(12):1705-16 [11101638.001]
  • [Cites] Spectrochim Acta A Mol Biomol Spectrosc. 2000 Dec;56(14):2799-809 [11145347.001]
  • [Cites] J Biochem. 2001 Jun;129(6):861-8 [11388899.001]
  • [Cites] J Nutr. 2001 Nov;131(11):2921-7 [11694619.001]
  • [Cites] Neurochem Res. 2001 Oct;26(10):1139-44 [11700956.001]
  • [Cites] Mol Cell Biol. 2001 Dec;21(24):8318-28 [11713268.001]
  • [Cites] J Nutr. 2001 Dec;131(12):3303-6 [11739884.001]
  • [Cites] J Nutr. 2002 May;132(5):946-51 [11983819.001]
  • [Cites] Mol Cell Biol. 2002 Jun;22(12):3970-80 [12024011.001]
  • [Cites] Nat Immunol. 2002 Aug;3(8):741-8 [12089510.001]
  • [Cites] Mol Immunol. 2002 Sep;38(16-18):1247-52 [12217391.001]
  • [Cites] Invest Ophthalmol Vis Sci. 2003 Jun;44(6):2694-701 [12766075.001]
  • [Cites] Mol Cells. 2003 Aug 31;16(1):97-105 [14503852.001]
  • [Cites] J Immunol. 2004 Apr 1;172(7):4486-92 [15034065.001]
  • [Cites] Blood. 2004 Jul 1;104(1):207-14 [15010370.001]
  • [Cites] Biol Pharm Bull. 2004 Jul;27(7):978-84 [15256726.001]
  • [Cites] Biophys J. 1984 Jun;45(6):1203-9 [6743750.001]
  • [Cites] J Immunol. 1989 May 15;142(10):3440-6 [2785556.001]
  • [Cites] J Immunol. 1990 Sep 1;145(5):1463-8 [2200824.001]
  • [Cites] J Biol Chem. 1993 Feb 5;268(4):2280-3 [8381401.001]
  • [Cites] Biochem Biophys Res Commun. 1996 Jun 14;223(2):245-9 [8670267.001]
  • [Cites] J Biol Chem. 1997 Feb 14;272(7):4276-80 [9020144.001]
  • [Cites] Nature. 1997 Jun 5;387(6633):569-72 [9177342.001]
  • [Cites] J Cell Sci. 1998 Aug;111 ( Pt 16):2385-96 [9683633.001]
  • [Cites] Physiol Rev. 1999 Oct;79(4):1089-125 [10508230.001]
  • [Cites] J Allergy Clin Immunol. 2004 Nov;114(5):1085-92 [15536414.001]
  • [Cites] Int Arch Allergy Immunol. 2005 Apr;136(4):311-9 [15722642.001]
  • [Cites] Int Immunol. 2005 Sep;17(9):1249-55 [16103029.001]
  • [Cites] Exp Mol Med. 2005 Aug 31;37(4):323-34 [16155409.001]
  • [Cites] Exp Eye Res. 2005 Oct;81(4):422-8 [15950219.001]
  • [Cites] J Immunol. 2005 Dec 1;175(11):7602-10 [16301670.001]
  • [Cites] J Biol Chem. 2005 Dec 2;280(48):40261-70 [16176929.001]
  • [Cites] Biochim Biophys Acta. 2005 Dec 30;1746(3):252-9 [16054713.001]
  • [Cites] Acta Biochim Pol. 2006;53(3):475-84 [16964324.001]
  • [Cites] J Agric Food Chem. 2006 Dec 27;54(26):9805-10 [17177505.001]
  • [Cites] Free Radic Biol Med. 2006 May 15;40(10):1820-6 [16678020.001]
  • (PMID = 19700409.001).
  • [ISSN] 1083-351X
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens; 0 / Monoterpenes; 0 / Receptors, IgE; 36-88-4 / Carotenoids; EC 3.2.1.52 / beta-N-Acetylhexosaminidases
  • [Other-IDs] NLM/ PMC2788868
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60. Matsushima M, Takagi K, Ogawa M, Hirose E, Ota Y, Abe F, Baba K, Hasegawa T, Hasegawa Y, Kawabe T: Heme oxygenase-1 mediates the anti-allergic actions of quercetin in rodent mast cells. Inflamm Res; 2009 Oct;58(10):705-15
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  • OBJECTIVE AND DESIGN: We investigated the involvement of heme oxygenase (HO)-1 in the anti-allergic action of quercetin against degranulation of rat basophilic leukemia (RBL-2H3) cells, rat peritoneal mast cells, and mouse bone marrow-derived mast cells.
  • [MeSH-minor] Animals. Bilirubin / pharmacology. Carbon Monoxide / pharmacology. Cells, Cultured. Disease Models, Animal. Enzyme Inhibitors / pharmacology. Heme Oxygenase (Decyclizing) / metabolism. Leukemia, Basophilic, Acute / metabolism. Leukemia, Basophilic, Acute / pathology. Metalloporphyrins / pharmacology. Mice. Mice, Inbred BALB C. NF-E2-Related Factor 2 / metabolism. Protoporphyrins / pharmacology. Rats. Rats, Wistar

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  • [Cites] Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):155-60 [15499042.001]
  • [Cites] Chest. 2005 Dec;128(6):4030-5 [16354877.001]
  • [Cites] Biochem Pharmacol. 2005 Jan 1;69(1):41-8 [15588712.001]
  • [Cites] Pharmacol Rev. 2000 Dec;52(4):673-751 [11121513.001]
  • [Cites] J Pharmacol Exp Ther. 2005 Feb;312(2):686-93 [15537827.001]
  • [Cites] Cancer Res. 1991 Feb 1;51(3):974-8 [1988141.001]
  • [Cites] Hepatology. 2004 Aug;40(2):424-33 [15368447.001]
  • [Cites] Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G695-703 [16537973.001]
  • [Cites] Biochem Pharmacol. 2005 Jun 15;69(12 ):1839-51 [15876423.001]
  • [Cites] Clin Exp Allergy. 2000 Apr;30(4):501-8 [10718847.001]
  • [Cites] Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2965-9 [8385353.001]
  • [Cites] Life Sci. 1999;65(4):337-53 [10421421.001]
  • [Cites] Biochem Pharmacol. 2003 Nov 1;66(9):1821-32 [14563492.001]
  • [Cites] Nature. 2003 Dec 18;426(6968):787-8; discussion 788 [14685225.001]
  • [Cites] J Biol Chem. 1997 Jul 18;272(29):18411-7 [9218484.001]
  • [Cites] Inflamm Res. 2004 Mar;53 Suppl 1:S9-S10 [15054594.001]
  • [Cites] Biochem Pharmacol. 1999 Apr 15;57(8):941-9 [10086329.001]
  • [Cites] Br Med Bull. 2000;56(4):936-55 [11359630.001]
  • [Cites] FASEB J. 2003 Nov;17 (14 ):2133-5 [12958158.001]
  • [Cites] Am J Physiol Heart Circ Physiol. 2002 Sep;283(3):H861-70 [12181112.001]
  • [Cites] Peptides. 2002 Aug;23(8):1507-15 [12182955.001]
  • [Cites] Mol Cell Biochem. 2006 Oct;291(1-2):21-8 [16625420.001]
  • [Cites] Mol Cell Biochem. 2003 Jan;243(1-2):153-60 [12619901.001]
  • [Cites] Nature. 1981 Jan 15;289(5794):186-7 [6161310.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Jul 17;98 (15):8798-803 [11447290.001]
  • [Cites] Biochim Biophys Acta. 1977 Aug 15;469(1):52-60 [70222.001]
  • [Cites] J Clin Invest. 2006 Mar;116(3):808-16 [16485041.001]
  • [Cites] Clin Exp Allergy. 2001 Sep;31(9):1470-7 [11591199.001]
  • [Cites] Biochem J. 2003 May 1;371(Pt 3):887-95 [12570874.001]
  • [Cites] Pharmacol Res. 2006 Feb;53(2):113-22 [16243536.001]
  • [Cites] Eur J Pharmacol. 2006 Feb 17;532(1-2):178-86 [16480975.001]
  • [Cites] Am J Physiol Cell Physiol. 2006 Apr;290(4):C1092-9 [16291820.001]
  • [Cites] Am J Respir Crit Care Med. 2005 Sep 15;172(6):660-70 [15901614.001]
  • [Cites] Nucleic Acids Res. 1998 Dec 1;26(23):5480-5 [9826775.001]
  • [Cites] Nat Med. 2000 Apr;6(4):422-8 [10742149.001]
  • [Cites] Biochem Pharmacol. 2000 Oct 15;60(8):1121-8 [11007950.001]
  • [Cites] Oncogene. 2001 Jun 28;20(29):3906-17 [11439354.001]
  • [Cites] J Immunol. 2000 Dec 1;165(11):6545-52 [11086097.001]
  • [Cites] Pharmacol Rev. 2003 Sep;55(3):551-71 [12869663.001]
  • [Cites] Int J Tissue React. 1996;18(1):1-21 [8880375.001]
  • [Cites] J Epidemiol Community Health. 2004 Apr;58(4):288-9 [15026440.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2004 Jul;287(1):L26-34 [15003924.001]
  • [Cites] Peptides. 2002 Oct;23(10):1713-7 [12383857.001]
  • [Cites] Inflamm Res. 1998;47 Suppl 1:S7-8 [9561391.001]
  • (PMID = 19390785.001).
  • [ISSN] 1420-908X
  • [Journal-full-title] Inflammation research : official journal of the European Histamine Research Society ... [et al.]
  • [ISO-abbreviation] Inflamm. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Enzyme Inhibitors; 0 / Metalloporphyrins; 0 / NF-E2-Related Factor 2; 0 / Protoporphyrins; 14325-05-4 / tin protoporphyrin IX; 7U1EE4V452 / Carbon Monoxide; 9IKM0I5T1E / Quercetin; EC 1.14.14.18 / Heme Oxygenase (Decyclizing); EC 1.14.14.18 / Heme Oxygenase-1; EC 1.14.14.18 / heme oxygenase-2; RFM9X3LJ49 / Bilirubin
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61. Shaik GM, Dráberová L, Heneberg P, Dráber P: Vacuolin-1-modulated exocytosis and cell resealing in mast cells. Cell Signal; 2009 Aug;21(8):1337-45
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  • Here we show that in rat basophilic leukemia (RBL-2H3) cells activated by the high-affinity IgE receptor (FcepsilonRI) triggering vacuolin-1 enhanced exocytosis.

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  • (PMID = 19376224.001).
  • [ISSN] 1873-3913
  • [Journal-full-title] Cellular signalling
  • [ISO-abbreviation] Cell. Signal.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Heterocyclic Compounds with 4 or More Rings; 0 / Receptors, IgE; 0 / vacuolin-1; SY7Q814VUP / Calcium
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62. Nowak-Wegrzyn AH, Bencharitiwong R, Schwarz J, David G, Eggleston P, Gergen PJ, Liu AH, Pongracic JA, Sarpong S, Sampson HA: Mediator release assay for assessment of biological potency of German cockroach allergen extracts. J Allergy Clin Immunol; 2009 Apr;123(4):949-955.e1
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  • OBJECTIVE: We investigated the utility of a mediator release assay based on rat basophil leukemia (RBL) cells for comparing the potency of German cockroach extracts.

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  • [Cites] J Allergy Clin Immunol. 1997 May;99(5):583-6 [9155821.001]
  • [Cites] Allergy. 2008 Mar;63(3):310-26 [18269676.001]
  • [Cites] Science. 1998 Jul 24;281(5376):568-72 [9677201.001]
  • [Cites] J Allergy Clin Immunol. 1998 Oct;102(4 Pt 1):563-70 [9802363.001]
  • [Cites] J Allergy Clin Immunol. 1999 Mar;103(3 Pt 1):501-6 [10069886.001]
  • [Cites] Allergy. 1999 May;54(5):446-54 [10380775.001]
  • [Cites] J Allergy Clin Immunol. 1999 Oct;104(4 Pt 1):842-6 [10518830.001]
  • [Cites] Cytometry B Clin Cytom. 2005 Mar;64(1):28-33 [15668987.001]
  • [Cites] J Allergy Clin Immunol. 2005 Apr;115(4):803-9 [15806002.001]
  • [Cites] Clin Immunol. 2005 Jun;115(3):302-12 [15893698.001]
  • [Cites] Clin Exp Allergy. 2007 Jan;37(1):141-50 [17210052.001]
  • [Cites] J Allergy Clin Immunol. 2007 Feb;119(2):270-7; quiz 278-9 [17166574.001]
  • [Cites] Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M. 2006;(95):117-27; discussion 127, 155 [17393731.001]
  • [Cites] J Allergy Clin Immunol. 2007 Apr;119(4):769-79 [17337297.001]
  • [Cites] J Investig Allergol Clin Immunol. 2000 Jan-Feb;10(1):24-9 [10780796.001]
  • [Cites] Allergy. 2000 May;55(5):476-83 [10843429.001]
  • [Cites] Int Arch Allergy Immunol. 2000 Aug;122(4):264-9 [10971117.001]
  • [Cites] Clin Exp Allergy. 2000 Nov;30(11):1583-9 [11069567.001]
  • [Cites] J Allergy Clin Immunol. 2001 Mar;107(3):419-28 [11240940.001]
  • [Cites] Clin Rev Allergy Immunol. 2001 Oct;21(2-3):141-52 [11725602.001]
  • [Cites] Am J Respir Crit Care Med. 2002 Feb 1;165(3):391-7 [11818327.001]
  • [Cites] Clin Exp Allergy. 2002 May;32(5):721-7 [11994096.001]
  • [Cites] Allergy. 2003 Jan;58(1):38-45 [12580805.001]
  • [Cites] J Immunol Methods. 2003 Mar 1;274(1-2):37-45 [12609531.001]
  • [Cites] J Allergy Clin Immunol. 2003 Apr;111(4):777-83 [12704357.001]
  • [Cites] Allergy. 2003 Oct;58(10):1037-43 [14510723.001]
  • [Cites] J Allergy. 1970 Jun;45(6):347-54 [4192485.001]
  • [Cites] J Allergy Clin Immunol. 1974 Sep;54(3):157-64 [4854999.001]
  • [Cites] Int Arch Allergy Appl Immunol. 1977;55(1-6):215-6 [73510.001]
  • [Cites] J Allergy Clin Immunol. 1982 Nov;70(5):343-52 [7130550.001]
  • [Cites] J Allergy Clin Immunol. 1986 Apr;77(4):555-7 [2420851.001]
  • [Cites] EMBO J. 1988 Dec 20;7(13):4101-9 [2977332.001]
  • [Cites] Allergy. 1990 Apr;45(3):231-5 [2183646.001]
  • [Cites] N Engl J Med. 1997 May 8;336(19):1356-63 [9134876.001]
  • [Cites] Allergy. 2005 Aug;60(8):1021-8 [15969682.001]
  • [Cites] Curr Opin Allergy Clin Immunol. 2006 Jun;6(3):226-33 [16670519.001]
  • [Cites] Allergy. 2006 Aug;61(8):988-95 [16867053.001]
  • [Cites] Clin Exp Allergy. 2007 Jul;37(7):1033-9 [17581196.001]
  • [Cites] J Allergy Clin Immunol. 2007 Jul;120(1):113-20 [17531297.001]
  • [Cites] J Allergy Clin Immunol. 2008 Jan;121(1):240-5 [17936887.001]
  • [Cites] Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M. 1997;(91):203-8 [9383911.001]
  • (PMID = 19348929.001).
  • [ISSN] 1097-6825
  • [Journal-full-title] The Journal of allergy and clinical immunology
  • [ISO-abbreviation] J. Allergy Clin. Immunol.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / K23 AI059318-01A1; United States / NIAID NIH HHS / AI / N01-AI-25482; United States / NIAID NIH HHS / AI / N01 AI025496; United States / NIAID NIH HHS / AI / AI 059318; United States / NIAID NIH HHS / AI / N01AI25496; United States / NIAID NIH HHS / AI / N01 AI025482; United States / NIAID NIH HHS / AI / K23 AI059318; United States / NIAID NIH HHS / AI / N01AI25482; United States / NIAID NIH HHS / AI / AI059318-01A1; United States / NIAID NIH HHS / AI / N01-AI-25496
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Allergens; 0 / Receptors, IgE; 37341-29-0 / Immunoglobulin E; EC 3.2.1.- / Hexosaminidases
  • [Other-IDs] NLM/ NIHMS109184; NLM/ PMC2952833
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63. Sun J, Wu Y, Wang J, Ma F, Liu X, Li Q: Novel translationally controlled tumor protein homologue in the buccal gland secretion of Lampetra japonica. Biochimie; 2008 Nov-Dec;90(11-12):1760-8

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  • It mediated histamine release from rat basophilic leukemia (RBL-2H3) cells.

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  • (PMID = 18822340.001).
  • [ISSN] 1638-6183
  • [Journal-full-title] Biochimie
  • [ISO-abbreviation] Biochimie
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Recombinant Proteins; 0 / tumor protein, translationally-controlled 1
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64. Ryu H, Walker JK, Kim S, Koo N, Barak LS, Noguchi T, Kang BY, Kim KM: Regulation of M2-type pyruvate kinase mediated by the high-affinity IgE receptors is required for mast cell degranulation. Br J Pharmacol; 2008 Jul;154(5):1035-46
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  • EXPERIMENTAL APPROACH: In rat basophilic leukaemia (RBL-2H3) cells, the effects of directly inhibiting M2PK or preventing the FcvarepsilonRI-mediated inhibition of M2PK (disinhibition) on degranulation was measured by hexosaminidase release.

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  • [Cites] Cesk Dermatol. 1982 Feb;57(1):23-6 [7074695.001]
  • [Cites] Planta Med. 2006 Jun;72(7):659-61 [16636972.001]
  • [Cites] Methods Enzymol. 1982;90 Pt E:150-65 [7154944.001]
  • [Cites] J Biol Chem. 1986 Oct 15;261(29):13807-12 [3020052.001]
  • [Cites] FASEB J. 1988 Jul;2(10):2605-8 [3384240.001]
  • [Cites] FEBS Lett. 1988 Dec 19;242(1):194-8 [2462512.001]
  • [Cites] Nature. 1989 Jan 12;337(6203):187-9 [2521376.001]
  • [Cites] J Biol Chem. 1989 Feb 5;264(4):2363-7 [2914912.001]
  • [Cites] Nature. 1989 Mar 30;338(6214):383-4 [2927501.001]
  • [Cites] J Pharmacol Exp Ther. 1990 May;253(2):688-97 [2338654.001]
  • [Cites] Przegl Dermatol. 1989 Sep-Dec;76(5-6):381-5 [2641806.001]
  • [Cites] Nature. 1992 Jan 2;355(6355):78-80 [1370575.001]
  • [Cites] Crit Rev Oncog. 1992;3(1-2):91-115 [1532331.001]
  • [Cites] J Biol Chem. 1993 Feb 5;268(4):2280-3 [8381401.001]
  • [Cites] Proc Natl Acad Sci U S A. 1993 May 15;90(10):4674-8 [7685108.001]
  • [Cites] J Biol Chem. 1993 Nov 5;268(31):23318-24 [7693687.001]
  • [Cites] J Biol Chem. 1993 Dec 5;268(34):25846-56 [7503989.001]
  • [Cites] Mol Cell Biol. 1995 Jul;15(7):3813-22 [7791788.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7686-9 [7644477.001]
  • [Cites] J Biol Chem. 1997 Mar 7;272(10):6805-11 [9045715.001]
  • [Cites] J Immunol. 1998 May 15;160(10):5136-44 [9590266.001]
  • [Cites] Am J Physiol. 1999 Apr;276(4 Pt 2):R1214-21 [10198406.001]
  • [Cites] Adv Immunol. 2000;76:325-55 [11079101.001]
  • [Cites] Endocrinology. 2001 Mar;142(3):1057-64 [11181519.001]
  • [Cites] Biochemistry. 2001 Jun 5;40(22):6589-97 [11380253.001]
  • [Cites] Nat Immunol. 2002 Aug;3(8):741-8 [12089510.001]
  • [Cites] Nat Immunol. 2002 Aug;3(8):707-8 [12145654.001]
  • [Cites] Neurochem Res. 2002 Sep;27(9):947-52 [12396106.001]
  • [Cites] J Inherit Metab Dis. 2002 Sep;25(5):333-46 [12408183.001]
  • [Cites] Curr Opin Immunol. 2002 Dec;14(6):688-93 [12413516.001]
  • [Cites] Arch Pharm Res. 2004 Jan;27(1):94-8 [14969346.001]
  • [Cites] Acta Pharmacol Toxicol (Copenh). 1967;25:Suppl 4:35 [4171624.001]
  • [Cites] J Allergy Clin Immunol. 1975 Oct;56(4):253-61 [51862.001]
  • [Cites] Clin Exp Immunol. 1976 Oct;26(1):162-8 [63342.001]
  • [Cites] Acta Biochim Pol. 1976;23(4):285-91 [1035019.001]
  • [Cites] Hoppe Seylers Z Physiol Chem. 1977 Aug;358(8):1047-55 [200542.001]
  • [Cites] Biull Eksp Biol Med. 1978 Sep;86(9):347-9 [100150.001]
  • [Cites] J Immunol. 1979 Oct;123(4):1445-50 [479592.001]
  • [Cites] Annu Rev Biochem. 1980;49:459-87 [6250446.001]
  • [Cites] J Immunol. 1981 Aug;127(2):546-50 [6166675.001]
  • [Cites] Int Arch Allergy Immunol. 1999 Jun;119(2):95-100 [10394100.001]
  • [Cites] J Biol Chem. 1999 Oct 1;274(40):28371-8 [10497197.001]
  • [Cites] Biochem Biophys Res Commun. 2004 Dec 3;325(1):117-23 [15522209.001]
  • [Cites] Proteomics. 2006 Jan;6(2):623-31 [16342142.001]
  • [Cites] J Immunol. 2006 Jun 15;176(12):7243-53 [16751367.001]
  • [Cites] Methods Enzymol. 1982;90 Pt E:140-9 [7154943.001]
  • (PMID = 18587448.001).
  • [ISSN] 0007-1188
  • [Journal-full-title] British journal of pharmacology
  • [ISO-abbreviation] Br. J. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Receptors, IgE; 9006-59-1 / Ovalbumin; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.1.40 / Pyruvate Kinase; EC 2.7.10.2 / src-Family Kinases; EC 2.7.11.13 / Protein Kinase C; EC 3.2.1.- / Hexosaminidases; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ PMC2451040
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65. Wagner S, Radauer C, Bublin M, Hoffmann-Sommergruber K, Kopp T, Greisenegger EK, Vogel L, Vieths S, Scheiner O, Breiteneder H: Naturally occurring hypoallergenic Bet v 1 isoforms fail to induce IgE responses in individuals with birch pollen allergy. J Allergy Clin Immunol; 2008 Jan;121(1):246-52

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  • Isoform structures were compared and related to IgE-binding inhibitory capacities and induction of mediator release in human Fcvarepsilon receptor transformed rat basophilic leukemia cells.

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  • (PMID = 17889932.001).
  • [ISSN] 1097-6825
  • [Journal-full-title] The Journal of allergy and clinical immunology
  • [ISO-abbreviation] J. Allergy Clin. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Allergens; 0 / Antibodies, Blocking; 0 / Antigens, Plant; 0 / Immunoglobulin G; 0 / Plant Proteins; 0 / Protein Isoforms; 126161-14-6 / Bet v 1 allergen, Betula; 37341-29-0 / Immunoglobulin E
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66. Thors L, Eriksson J, Fowler CJ: Inhibition of the cellular uptake of anandamide by genistein and its analogue daidzein in cells with different levels of fatty acid amide hydrolase-driven uptake. Br J Pharmacol; 2007 Nov;152(5):744-50
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  • BACKGROUND AND PURPOSE: Genistein, a tyrosine kinase inhibitor used to block caveolae dependent endocytosis, reduces the cellular uptake of anandamide in RBL2H3 basophilic leukaemia cells.

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  • [Cites] J Biol Chem. 1999 Oct 29;274(44):31119-22 [10531298.001]
  • [Cites] Br J Pharmacol. 2007 Apr;150(7):951-60 [17325653.001]
  • [Cites] Chem Phys Lipids. 2000 Nov;108(1-2):123-34 [11106786.001]
  • [Cites] J Biol Chem. 2001 Mar 9;276(10):6967-73 [11118429.001]
  • [Cites] J Biol Chem. 2002 Apr 19;277(16):13673-81 [11834728.001]
  • [Cites] Biochem J. 2002 Oct 1;367(Pt 1):203-8 [12095417.001]
  • [Cites] FEBS Lett. 2002 Nov 6;531(2):343-7 [12417339.001]
  • [Cites] Nat Med. 2003 Jan;9(1):76-81 [12461523.001]
  • [Cites] J Cell Sci. 2003 Dec 1;116(Pt 23):4707-14 [14600257.001]
  • [Cites] Br J Pharmacol. 2004 Feb;141(3):457-67 [14718261.001]
  • [Cites] Eur J Pharm Sci. 2004 Jun;22(2-3):181-9 [15158903.001]
  • [Cites] Biochemistry. 2004 Jun 29;43(25):8184-90 [15209515.001]
  • [Cites] Eur J Neurosci. 2004 Jul;20(2):459-66 [15233754.001]
  • [Cites] J Biochem Biophys Methods. 2004 Aug 31;60(2):171-7 [15262451.001]
  • [Cites] J Biol Chem. 2004 Oct 1;279(40):41991-7 [15292270.001]
  • [Cites] Biochem J. 1974 Jun;139(3):715-20 [4854723.001]
  • [Cites] J Biol Chem. 1985 Nov 15;260(26):14145-9 [4055775.001]
  • [Cites] J Biol Chem. 1987 Apr 25;262(12):5592-5 [3106339.001]
  • [Cites] Biochem Pharmacol. 1993 Sep 1;46(5):791-6 [8373432.001]
  • [Cites] Nature. 1994 Dec 15;372(6507):686-91 [7990962.001]
  • [Cites] J Biol Chem. 1997 Feb 7;272(6):3315-23 [9013571.001]
  • [Cites] Neurosci Lett. 1998 Oct 2;254(3):137-40 [10214976.001]
  • [Cites] Pharmacol Ther. 2004 Nov;104(2):117-35 [15518883.001]
  • [Cites] Life Sci. 2005 Feb 25;76(15):1747-57 [15698853.001]
  • [Cites] Cell Mol Life Sci. 2005 Feb;62(3):386-95 [15723173.001]
  • [Cites] Chem Phys Lipids. 2005 Apr;134(2):131-9 [15784231.001]
  • [Cites] J Neurosci Res. 2005 Jul 15;81(2):275-83 [15920744.001]
  • [Cites] APMIS. 2005 May;113(5):332-9 [16011659.001]
  • [Cites] Histochem Cell Biol. 2005 Jun;123(6):613-20 [15889267.001]
  • [Cites] J Lipid Res. 2005 Aug;46(8):1652-9 [15930521.001]
  • [Cites] Life Sci. 2005 Aug 19;77(14):1584-604 [15979096.001]
  • [Cites] J Biol Chem. 2006 Apr 7;281(14):9066-75 [16461355.001]
  • [Cites] J Am Chem Soc. 2006 Aug 2;128(30):9699-704 [16866524.001]
  • [Cites] Br J Pharmacol. 2006 Sep;149(1):73-81 [16865094.001]
  • [Cites] Pharmacol Res. 2006 Dec;54(6):481-5 [16997568.001]
  • [Cites] Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):407-23 [16736384.001]
  • [Cites] Cell Mol Life Sci. 2007 Jan;64(2):219-29 [17187172.001]
  • [Cites] J Pharmacol Exp Ther. 2000 Mar;292(3):960-7 [10688610.001]
  • (PMID = 17676056.001).
  • [ISSN] 0007-1188
  • [Journal-full-title] British journal of pharmacology
  • [ISO-abbreviation] Br. J. Pharmacol.
  • [Language] ENG
  • [Grant] United States / NIDA NIH HHS / DA / DA009789-12A17961; United States / NIDA NIH HHS / DA / P01 DA009789; United States / NIDA NIH HHS / DA / P01 DA009789-12A17961
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Arachidonic Acids; 0 / Benzamides; 0 / Carbamates; 0 / Endocannabinoids; 0 / Isoflavones; 0 / Polyunsaturated Alkamides; 0 / Protein Kinase Inhibitors; 0 / cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester; 10028-17-8 / Tritium; 6287WC5J2L / daidzein; 94421-68-8 / anandamide; DH2M523P0H / Genistein; EC 3.5.- / Amidohydrolases; EC 3.5.1.- / fatty-acid amide hydrolase
  • [Other-IDs] NLM/ PMC2190009
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67. Matsui T, Ito C, Itoigawa M, Okada T, Furukawa H: Anti-inflammatory activity of phenylpropanoids and phytoquinoids from Illicium species in RBL-2H3 cells. Planta Med; 2007 Jun;73(7):662-5
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  • Two phenylpropanoids, 1-allyl-3,5-dimethoxy-4-(3-methyl-but-2-enyloxy)benzene ( 4) and 4-allyl-2,6-dimethoxy-3-(3-methyl-2-butenyl)phenol ( 6), and two phytoquinoids, 4 R-(-)-illicinone-A ( 7) and 2 S,4 R-(-)-illicinone-B ( 8), isolated from plants of the ILLICIUM species significantly inhibited histamine release from rat basophilic leukemia (RBL-2H3) cells stimulated with A23187.

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  • (PMID = 17538871.001).
  • [ISSN] 0032-0943
  • [Journal-full-title] Planta medica
  • [ISO-abbreviation] Planta Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Plant Extracts
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68. Teshima R, Amano F, Nakamura R, Tanaka Y, Sawada J: Effects of polyunsaturated fatty acids on calcium response and degranulation from RBL-2H3 cells. Int Immunopharmacol; 2007 Feb;7(2):205-10
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  • To investigate the biological activity of various polyunsaturated fatty acids (PUFAs) on the allergic reaction, we examined the effects of six PUFAs and two saturated fatty acids on calcium response and degranulation from rat basophilic leukemia (RBL-2H3) cells.

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  • (PMID = 17178388.001).
  • [ISSN] 1567-5769
  • [Journal-full-title] International immunopharmacology
  • [ISO-abbreviation] Int. Immunopharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Allergic Agents; 0 / Fatty Acids, Unsaturated; 85166-31-0 / Inositol 1,4,5-Trisphosphate; SY7Q814VUP / Calcium
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69. Chikamatsu S, Furuno T, Kinoshita Y, Inoh Y, Hirashima N, Teshima R, Nakanishi M: Effects of Cot expression on the nuclear translocation of NF-kappaB in RBL-2H3 cells. Mol Immunol; 2007 Mar;44(7):1490-7
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  • Here we have shown that Cot kinase activity is intimately involved in the high affinity receptor for IgE (FcvarepsilonRI)-mediated nuclear translocation of NF-kappaB1 independent of NF-kappaB-inducing kinase (NIK) in rat basophilic leukemia (RBL-2H3) cells.

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  • (PMID = 17049604.001).
  • [ISSN] 0161-5890
  • [Journal-full-title] Molecular immunology
  • [ISO-abbreviation] Mol. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Luminescent Proteins; 0 / NF-kappa B; 0 / Proto-Oncogene Proteins; 0 / Receptors, IgE; 0 / red fluorescent protein; 147336-22-9 / Green Fluorescent Proteins; EC 2.7.11.25 / MAP Kinase Kinase Kinases; EC 2.7.11.25 / Map3k8 protein, rat
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70. Buku A, Condie BA, Price JA, Mezei M: [Ala12]MCD peptide: a lead peptide to inhibitors of immunoglobulin E binding to mast cell receptors. J Pept Res; 2005 Sep;66(3):132-7
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  • In contrast to MCD peptide, [Ala12]MCD showed a 50% inhibition of IgE binding to the Fc epsilon RI alpha mast cell receptor by using rat basophilic leukemia (RBL-2H3) mast cells and fluorescence polarization.

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  • (PMID = 16083440.001).
  • [ISSN] 1397-002X
  • [Journal-full-title] The journal of peptide research : official journal of the American Peptide Society
  • [ISO-abbreviation] J. Pept. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Peptides; 0 / Receptors, Cell Surface; 32908-73-9 / mast cell degranulating peptide; 37341-29-0 / Immunoglobulin E; EC 3.2.1.52 / beta-N-Acetylhexosaminidases; OF5P57N2ZX / Alanine
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71. Avril T, Freeman SD, Attrill H, Clarke RG, Crocker PR: Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation. J Biol Chem; 2005 May 20;280(20):19843-51
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  • To investigate the role of these motifs in Siglec-5-dependent signaling, we used transfected rat basophil leukemia cells as a model system.

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  • (PMID = 15769739.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Intracellular Signaling Peptides and Proteins; 0 / Lectins; 0 / Recombinant Fusion Proteins; 0 / SIGLEC5 protein, human; 42HK56048U / Tyrosine; 9007-49-2 / DNA; EC 3.1.3.48 / PTPN11 protein, human; EC 3.1.3.48 / PTPN6 protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatase, Non-Receptor Type 11; EC 3.1.3.48 / Protein Tyrosine Phosphatase, Non-Receptor Type 6; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.1.3.48 / Ptpn11 protein, rat; EC 3.1.3.48 / Ptpn6 protein, rat
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72. Onnis V, Congiu C, Björklund E, Hempel F, Söderström E, Fowler CJ: Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors. J Med Chem; 2010 Mar 11;53(5):2286-98
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  • The compound was also able to inhibit the FAAH activity in rat basophilic leukemia cells as assessed by measuring either the hydrolysis of anandamide, the FAAH-dependent cellular accumulation of anandamide, or the FAAH-dependent recycling of tritium to the cell membranes.

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  • (PMID = 20143779.001).
  • [ISSN] 1520-4804
  • [Journal-full-title] Journal of medicinal chemistry
  • [ISO-abbreviation] J. Med. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Analgesics; 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Arachidonic Acids; 0 / Benzoates; 0 / Endocannabinoids; 0 / Enzyme Inhibitors; 0 / Polyunsaturated Alkamides; 0 / Pyridines; 94421-68-8 / anandamide; EC 3.5.- / Amidohydrolases; EC 3.5.1.- / fatty-acid amide hydrolase
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73. Jung ID, Lee HS, Lee HY, Choi OH: FcepsilonRI-mediated mast cell migration: signaling pathways and dependence on cytosolic free Ca2+ concentration. Cell Signal; 2009 Nov;21(11):1698-705
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  • IgE-sensitized rat basophilic leukemia (RBL)-2H3 mast cells have been shown to migrate towards antigen.

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  • [Cites] Immunity. 2007 Mar;26(3):287-97 [17346996.001]
  • [Cites] Cell Calcium. 2009 Feb;45(2):99-108 [18675457.001]
  • [Cites] J Clin Pathol. 2007 Jun;60(6):600-7 [17557865.001]
  • [Cites] Int Ophthalmol. 2007 Aug;27(4):235-9 [17464452.001]
  • [Cites] Nature. 1999 Nov 25;402(6760 Suppl):B24-30 [10586892.001]
  • [Cites] Curr Opin Immunol. 2000 Dec;12(6):624-31 [11102764.001]
  • [Cites] Leuk Res. 2001 Jul;25(7):511-8 [11377675.001]
  • [Cites] J Immunol. 2001 Aug 15;167(4):2298-304 [11490018.001]
  • [Cites] Hum Pathol. 2001 Nov;32(11):1174-83 [11727255.001]
  • [Cites] Science. 2001 Nov 30;294(5548):1875-8 [11729304.001]
  • [Cites] J Biol Chem. 2002 May 10;277(19):17255-62 [11856736.001]
  • [Cites] J Biol Chem. 2002 Jul 12;277(28):25152-9 [12006579.001]
  • [Cites] Curr Opin Immunol. 2002 Dec;14(6):688-93 [12413516.001]
  • [Cites] Cell. 2002 Nov 15;111(4):529-41 [12437926.001]
  • [Cites] J Exp Med. 2003 Jun 2;197(11):1453-65 [12782712.001]
  • [Cites] EMBO J. 2003 Oct 15;22(20):5491-500 [14532121.001]
  • [Cites] Methods Mol Biol. 2004;249:153-66 [14573898.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12911-6 [14569021.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2323-7 [14983008.001]
  • [Cites] J Exp Med. 2004 Apr 5;199(7):959-70 [15067032.001]
  • [Cites] Blood. 2004 Apr 15;103(8):3093-101 [15070690.001]
  • [Cites] J Biochem. 2004 Jun;135(6):673-81 [15213242.001]
  • [Cites] Mol Cell Biol. 2004 Oct;24(19):8765-77 [15367693.001]
  • [Cites] FEBS Lett. 1991 Sep 2;289(1):47-50 [1832647.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9686-90 [1409683.001]
  • [Cites] Anal Biochem. 1994 Dec;223(2):306-12 [7887476.001]
  • [Cites] J Biol Chem. 1995 Apr 28;270(17):10272-7 [7730331.001]
  • [Cites] J Cell Biol. 1995 Jul;130(1):193-206 [7790372.001]
  • [Cites] Nature. 1996 Apr 18;380(6575):634-6 [8602265.001]
  • [Cites] J Biol Chem. 1998 Jan 30;273(5):2910-6 [9446602.001]
  • [Cites] FEBS Lett. 1999 Jan 22;443(1):25-30 [9928946.001]
  • [Cites] Mol Pharmacol. 1999 May;55(5):787-94 [10220556.001]
  • [Cites] J Biol Chem. 1999 Aug 20;274(34):23940-7 [10446161.001]
  • [Cites] Blood. 2005 Apr 15;105(8):3222-9 [15637135.001]
  • [Cites] Blood. 2005 Jun 15;105(12):4736-42 [15741218.001]
  • [Cites] Methods Mol Biol. 2006;315:13-34 [16110146.001]
  • [Cites] Methods Mol Biol. 2006;315:105-12 [16110152.001]
  • [Cites] Cell Calcium. 2005 Dec;38(6):581-92 [16219349.001]
  • [Cites] J Biol Chem. 2006 Feb 3;281(5):2515-25 [16316995.001]
  • [Cites] Immunol Res. 2006;34(2):97-115 [16760571.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16394-9 [17050692.001]
  • [Cites] Blood. 2008 Apr 15;111(8):4193-200 [18178871.001]
  • [Cites] Blood. 2008 Aug 15;112(4):1269-79 [18524989.001]
  • [Cites] J Biol Chem. 2007 Apr 20;282(16):12058-65 [17311928.001]
  • (PMID = 19632319.001).
  • [ISSN] 1873-3913
  • [Journal-full-title] Cellular signalling
  • [ISO-abbreviation] Cell. Signal.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL068879-02; United States / NHLBI NIH HHS / HL / R01 HL068879-04; United States / NHLBI NIH HHS / HL / R01 HL068879-05; United States / NHLBI NIH HHS / HL / HL068879-04; United States / NHLBI NIH HHS / HL / HL068879-02; United States / NHLBI NIH HHS / HL / HL068879-05; United States / NHLBI NIH HHS / HL / HL068879-03; United States / NHLBI NIH HHS / HL / R01 HL68879; United States / NHLBI NIH HHS / HL / R01 HL068879-03; United States / NHLBI NIH HHS / HL / R01 HL068879
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Lysophospholipids; 0 / Receptors, IgE; 0 / Receptors, Lysosphingolipid; 26993-30-6 / sphingosine 1-phosphate; 37341-29-0 / Immunoglobulin E; EC 2.4.2.31 / Pertussis Toxin; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; NGZ37HRE42 / Sphingosine; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ NIHMS139214; NLM/ PMC2752894
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74. Matsui T, Ito C, Itoigawa M, Okada T, Furukawa H: Effect of natsudaidain isolated from Citrus plants on TNF-alpha and cyclooxygenase-2 expression in RBL-2H3 cells. J Pharm Pharmacol; 2009 Jan;61(1):109-14
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  • METHODS: We investigated the inhibitory effects of natsudaidain, which is a polymethoxyflavone isolated from Citrus plants, on histamine release, tumour necrosis factor-alpha production and cyclooxygenase-2 expression in Ca ionophore-stimulated rat basophilic leukemia cells (A23187-stimulated RBL-2H3 cells) by spectrofluorometric, ELISA and immunoblotting methods.

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  • (PMID = 19126304.001).
  • [ISSN] 0022-3573
  • [Journal-full-title] The Journal of pharmacy and pharmacology
  • [ISO-abbreviation] J. Pharm. Pharmacol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Flavones; 0 / Flavonoids; 0 / Ionophores; 0 / RNA, Messenger; 0 / Tumor Necrosis Factor-alpha; 35154-55-3 / natsudaidain; 37H9VM9WZL / Calcimycin; D65ILJ7WLY / nobiletin; EC 1.14.99.1 / Cyclooxygenase 2; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases
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75. Matsui T, Nunomura S, Shimokawa T, Yoshimaru T, Ra C: Functionality of the IgA Fc receptor (FcalphaR, CD89) is down-regulated by extensive engagement of FcepsilonRI. Clin Immunol; 2008 Oct;129(1):155-62
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  • Transfected rat basophilic leukemia cell line (RBL-2H3) co-expressing FcepsilonRI and FcalphaR was analyzed for effects of simultaneous receptor engagement by their specific antibodies on degranulation and signaling.

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  • (PMID = 18700185.001).
  • [ISSN] 1521-7035
  • [Journal-full-title] Clinical immunology (Orlando, Fla.)
  • [ISO-abbreviation] Clin. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD; 0 / Bicyclo Compounds, Heterocyclic; 0 / Fc(alpha) receptor; 0 / Receptors, Fc; 0 / Receptors, IgE; 0 / Thiazolidines; 76343-94-7 / latrunculin B; EC 3.1.3.- / Phosphoric Monoester Hydrolases; EC 3.1.3.56 / inositol-polyphosphate 5-phosphatase
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76. Huang LS, Kim MR, Sok DE: Regulation of lipoxygenase activity by polyunsaturated lysophosphatidylcholines or their oxygenation derivatives. J Agric Food Chem; 2008 Sep 10;56(17):7808-14

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  • Likewise, arachidonoyl lysoPC and docosahexaenoyl lysoPC also inhibited 5-LOX activity from rat basophilic leukemia cells-2H3 (RBL-2H3) with IC50 values (50% inhibitory concentration) of 18.5 +/- 3.06 and 30.6 +/- 1.06 microM, respectively.
  • [MeSH-minor] Animals. Arachidonate 5-Lipoxygenase / metabolism. Cell Line, Tumor. Leukemia, Basophilic, Acute. Lipoxygenase Inhibitors / pharmacology. Rats. Solanum tuberosum / enzymology. Soybeans / enzymology

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  • (PMID = 18680379.001).
  • [ISSN] 1520-5118
  • [Journal-full-title] Journal of agricultural and food chemistry
  • [ISO-abbreviation] J. Agric. Food Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lipoxygenase Inhibitors; 0 / Lysophosphatidylcholines; EC 1.13.11.12 / Lipoxygenase; EC 1.13.11.34 / Arachidonate 5-Lipoxygenase
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77. Yamada P, Zarrouk M, Kawasaki K, Isoda H: Inhibitory effect of various Tunisian olive oils on chemical mediator release and cytokine production by basophilic cells. J Ethnopharmacol; 2008 Mar 5;116(2):279-87

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  • [Title] Inhibitory effect of various Tunisian olive oils on chemical mediator release and cytokine production by basophilic cells.
  • To investigate the antiallergic effect of virgin olive oil samples from five principal olive varieties grown in various regions of Tunisia, we used the type I allergy reaction model using rat basophilic leukemia (RBL-2H3) cells and different dilutions of olive oil samples to determine beta-hexosaminidase release inhibition at two different response stages.
  • Moreover, we investigated the effect of olive oil samples on histamine release and production of cytokines by activated human basophilic (KU812) cells.
  • [MeSH-major] Leukemia, Basophilic, Acute / metabolism. Plant Oils / pharmacology. Tumor Necrosis Factor-alpha / biosynthesis

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  • (PMID = 18178046.001).
  • [ISSN] 0378-8741
  • [Journal-full-title] Journal of ethnopharmacology
  • [ISO-abbreviation] J Ethnopharmacol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Inflammation Mediators; 0 / Olive Oil; 0 / Plant Oils; 0 / Tumor Necrosis Factor-alpha; 207137-56-2 / Interleukin-4; EC 3.2.1.52 / beta-N-Acetylhexosaminidases
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78. Arthur JF, Shen Y, Kahn ML, Berndt MC, Andrews RK, Gardiner EE: Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane. J Biol Chem; 2007 Oct 19;282(42):30434-41
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  • To identify the thiol involved in disulfide bond formation, wild-type or mutant GPVI, where two available sulfhydryls (Cys-274 and Cys-338) were individually mutated to serine, was expressed in rat basophilic leukemia cells.

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  • (PMID = 17690106.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Crotalid Venoms; 0 / Dipeptides; 0 / Disulfides; 0 / Intracellular Signaling Peptides and Proteins; 0 / Lectins, C-Type; 0 / Ligands; 0 / N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide; 0 / Platelet Glycoprotein GPIIb-IIIa Complex; 0 / Platelet Membrane Glycoproteins; 0 / Protease Inhibitors; 0 / platelet membrane glycoprotein VI; 37206-04-5 / convulxin; 9007-34-5 / Collagen; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Syk kinase; EC 2.7.10.2 / src-Family Kinases; EC 3.4.- / Metalloproteases
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79. Tefferi A, Elliott MA, Pardanani A: Atypical myeloproliferative disorders: diagnosis and management. Mayo Clin Proc; 2006 Apr;81(4):553-63
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  • The World Health Organization system for classification of tumors of the hematopoietic system divides myeloid disorders into acute myeloid leukemia and chronic myeloid disorders based on the presence or absence, respectively, of acute myeloid leukemia--defining morphological and cytogenetic features including the presence of 20% or more myeloblasts in either the bone marrow or the peripheral blood.
  • Classic MPD includes polycythemia vera, essential thrombocythemia, myelofibrosis with myeloid metaplasia, and chronic myeloid leukemia.
  • The current review focuses on the diagnosis and treatment of both molecularly defined and clinicopathologically assigned categories of atypical MPD: chronic myelomonocytic leukemia, juvenile myelomonocytic leukemia, chronic neutrophilic leukemia, chronic basophilic leukemia, chronic eosinophilic leukemia, idiopathic eosinophilia including hypereosinophilic syndrome, systemic mastocytosis, unclassified MPD, and eosinophilic/mast cell disorders associated with mutations of platelet-derived growth factor receptors alpha (PDGFRA) and beta (PDGFRB), FGFR1, and KIT.

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  • (PMID = 16610578.001).
  • [ISSN] 0025-6196
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 173
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80. Bandbon Balenga NA, Thalhamer J, Weiss R: Bicistronic expression plasmid encoding allergen and anti-IgE single chain variable fragment antibody as a novel DNA vaccine for allergy therapy and prevention. Med Hypotheses; 2006;67(1):71-4
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  • Also, rat basophil leukemia cell assay (using RBL-2H3 cells) can show the amount of functional IgE in sera as basophil mediator release is regarded as an indicator of the allergic hypersensitive reactions.

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  • (PMID = 16513289.001).
  • [ISSN] 0306-9877
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Antibodies, Anti-Idiotypic; 0 / Immunoglobulin Variable Region; 0 / Vaccines, DNA; 0 / anti-IgE antibodies; 37341-29-0 / Immunoglobulin E
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81. Nunomura S, Kitanaka S, Ra C: 3-O-(2,3-dimethylbutanoyl)-13-O-decanoylingenol from Euphorbia kansui suppresses IgE-mediated mast cell activation. Biol Pharm Bull; 2006 Feb;29(2):286-90
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  • We recently found that 3-O-(2,3-dimethylbutanoyl)-13-O-decanoylingenol (DBDI), purified from the Euphorbia kansui L., inhibits degranulation in rat basophilic leukemia 2H3 cells upon aggregation of the FcepsilonRI.

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  • (PMID = 16462033.001).
  • [ISSN] 0918-6158
  • [Journal-full-title] Biological & pharmaceutical bulletin
  • [ISO-abbreviation] Biol. Pharm. Bull.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / 3-O-(2,3-dimethylbutanoyl)-13-O-decanoylingenol; 0 / Diterpenes; 0 / Eicosanoids; 0 / Receptors, IgE; 37341-29-0 / Immunoglobulin E; EC 3.2.1.52 / beta-N-Acetylhexosaminidases; SY7Q814VUP / Calcium
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82. Hepp R, Puri N, Hohenstein AC, Crawford GL, Whiteheart SW, Roche PA: Phosphorylation of SNAP-23 regulates exocytosis from mast cells. J Biol Chem; 2005 Feb 25;280(8):6610-20
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  • We have investigated the molecular mechanisms of regulated exocytosis in mast cells and find that SNAP-23 is phosphorylated when rat basophilic leukemia mast cells are triggered to degranulate.
  • Regulated exocytosis studies revealed that overexpression of SNAP-23 phosphorylation mutants inhibited exocytosis from rat basophilic leukemia mast cells, demonstrating that phosphorylation of SNAP-23 on Ser(120) and Ser(95) modulates regulated exocytosis by mast cells.

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  • (PMID = 15611044.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Membrane Proteins; 0 / Qa-SNARE Proteins; 0 / R-SNARE Proteins; 0 / SNARE Proteins; 0 / Snap23 protein, rat; 0 / Vesicular Transport Proteins; 452VLY9402 / Serine
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83. Qu X, Li Y, Liu J, Xu L, Zhang Y, Hu X, Hou K, Liu Y: Cbl-b promotes chemotherapy-induced apoptosis in rat basophilic leukemia cells by suppressing PI3K/Akt activation and enhancing MEK/ERK activation. Mol Cell Biochem; 2010 Jul;340(1-2):107-14
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  • [Title] Cbl-b promotes chemotherapy-induced apoptosis in rat basophilic leukemia cells by suppressing PI3K/Akt activation and enhancing MEK/ERK activation.
  • [MeSH-major] Adaptor Proteins, Signal Transducing / metabolism. Antimetabolites, Antineoplastic / pharmacology. Antineoplastic Agents, Phytogenic / pharmacology. Apoptosis / drug effects. Extracellular Signal-Regulated MAP Kinases / metabolism. Leukemia, Basophilic, Acute / enzymology. Mitogen-Activated Protein Kinase Kinases / metabolism. Phosphatidylinositol 3-Kinases / metabolism. Proto-Oncogene Proteins c-akt / metabolism. Proto-Oncogene Proteins c-cbl / metabolism

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  • [Cites] J Immunol. 2006 Nov 1;177(9):5980-9 [17056522.001]
  • [Cites] Blood. 2004 Mar 1;103(5):1779-86 [14604964.001]
  • [Cites] Nature. 2000 Jan 13;403(6766):211-6 [10646608.001]
  • [Cites] Leukemia. 2007 Sep;21(9):1921-30 [17581609.001]
  • [Cites] Cancer Res. 2007 Feb 1;67(3):1203-11 [17283156.001]
  • [Cites] Oncogene. 1995 Jun 15;10(12):2367-77 [7784085.001]
  • [Cites] J Biol Chem. 2001 Feb 16;276(7):4872-8 [11087752.001]
  • [Cites] J Immunol. 2008 Oct 15;181(8):5331-9 [18832689.001]
  • [Cites] Cancer. 2003 Oct 1;98(7):1521-30 [14508841.001]
  • [Cites] Blood. 2007 Aug 1;110(3):1022-4 [17475912.001]
  • [Cites] Biochem Biophys Res Commun. 2008 Feb 29;367 (1):183-9 [18164258.001]
  • [Cites] Cancer Res. 2008 Aug 1;68(15):6271-80 [18676851.001]
  • [Cites] Eur J Haematol. 2003 Apr;70(4):219-24 [12656744.001]
  • [Cites] FEBS Lett. 2009 Jul 7;583(13):2255-62 [19508871.001]
  • [Cites] J Pathol. 2009 Jun;218(2):248-55 [19274672.001]
  • [Cites] J Biol Chem. 2005 Sep 9;280(36):31498-507 [16014620.001]
  • [Cites] Br J Haematol. 2005 Jun;129(5):677-86 [15916691.001]
  • [Cites] Biochim Biophys Acta. 2006 Sep;1763(9):958-68 [16905201.001]
  • [Cites] Oncogene. 2002 Feb 21;21(9):1423-33 [11857085.001]
  • [Cites] Mol Cancer Ther. 2008 Oct;7(10 ):3141-9 [18852117.001]
  • [Cites] Nat Immunol. 2001 Sep;2(9):870-5 [11526404.001]
  • [Cites] Immunity. 2007 May;26(5):567-78 [17493844.001]
  • [Cites] Nature. 2000 Jan 13;403(6766):216-20 [10646609.001]
  • [Cites] Mutagenesis. 2006 Mar;21(2):105-14 [16500949.001]
  • [Cites] Biochem Biophys Res Commun. 1995 Aug 24;213(3):837-44 [7654245.001]
  • [Cites] Neoplasia. 2008 Oct;10 (10 ):1083-91 [18813358.001]
  • (PMID = 20177738.001).
  • [ISSN] 1573-4919
  • [Journal-full-title] Molecular and cellular biochemistry
  • [ISO-abbreviation] Mol. Cell. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents, Phytogenic; 0 / Enzyme Inhibitors; 04079A1RDZ / Cytarabine; 6PLQ3CP4P3 / Etoposide; EC 2.3.2.27 / Proto-Oncogene Proteins c-cbl; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 2.7.12.2 / Mitogen-Activated Protein Kinase Kinases; EC 6.3.2.19 / Cblb protein, rat
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84. Evans NE, Forth MK, Simpson AK, Mason MJ: Inhibition by calyculin A and okadaic acid of the Ca(2+) release-activated Ca(2+) entry pathway in rat basophilic leukemia cells: evidence for regulation by type 1/2A serine/threonine phosphatase activity. Biochim Biophys Acta; 2005 Dec 10;1718(1-2):32-43
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  • [Title] Inhibition by calyculin A and okadaic acid of the Ca(2+) release-activated Ca(2+) entry pathway in rat basophilic leukemia cells: evidence for regulation by type 1/2A serine/threonine phosphatase activity.
  • Using a combination of fluorescence measurements of intracellular Ca(2+) ion concentration ([Ca(2+)](i)) and membrane potential we have investigated the sensitivity to serine/threonine phosphatase inhibition of Ca(2+) entry stimulated by activation of the Ca(2+) release-activated Ca(2+) (CRAC) entry pathway in rat basophilic leukemia cells.
  • [MeSH-minor] Animals. Boron Compounds / pharmacology. Cations, Divalent / metabolism. Cells, Cultured. Ion Transport / drug effects. Leukemia, Basophilic, Acute. Manganese / metabolism. Membrane Potentials / drug effects. Protein Phosphatase 1. Rats. Thapsigargin / pharmacology

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  • (PMID = 16297373.001).
  • [ISSN] 0006-3002
  • [Journal-full-title] Biochimica et biophysica acta
  • [ISO-abbreviation] Biochim. Biophys. Acta
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / 2-aminoethoxydiphenyl borate; 0 / Boron Compounds; 0 / Cations, Divalent; 0 / Enzyme Inhibitors; 0 / Oxazoles; 101932-71-2 / calyculin A; 1W21G5Q4N2 / Okadaic Acid; 42Z2K6ZL8P / Manganese; 67526-95-8 / Thapsigargin; EC 3.1.3.16 / Phosphoprotein Phosphatases; EC 3.1.3.16 / Protein Phosphatase 1; SY7Q814VUP / Calcium
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85. Hochwallner H, Schulmeister U, Swoboda I, Balic N, Geller B, Nystrand M, Härlin A, Thalhamer J, Scheiblhofer S, Niggemann B, Quirce S, Ebner C, Mari A, Pauli G, Herz U, van Tol EA, Valenta R, Spitzauer S: Microarray and allergenic activity assessment of milk allergens. Clin Exp Allergy; 2010 Dec;40(12):1809-18

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  • The allergenic activity of the individual allergens was tested using patients' sera for loading rat basophil leukaemia cells (RBL) expressing the α-chain of the human receptor FcεRI.

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  • [Copyright] © 2010 Blackwell Publishing Ltd.
  • (PMID = 20860558.001).
  • [ISSN] 1365-2222
  • [Journal-full-title] Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • [ISO-abbreviation] Clin. Exp. Allergy
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Allergens; 0 / Antigens, CD; 0 / Fc(alpha) receptor; 0 / Milk Proteins; 0 / Receptors, Fc; 37341-29-0 / Immunoglobulin E
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86. Chandrasekaran CV, Gupta A, Agarwal A: Effect of an extract of Andrographis paniculata leaves on inflammatory and allergic mediators in vitro. J Ethnopharmacol; 2010 May 27;129(2):203-7
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  • MATERIALS AND METHODS: Effect of an extract of Andrographis paniculata leaves (AP) was studied on inhibition of LPS induced NO, PGE(2), IL-1 beta and IL-6 in J774A.1 murine macrophages; A23187 induced LTB(4) and TXB(2) in HL-60 promyelocytic leukemic cells and histamine in RBL-2H3 rat basophilic leukemia cells.

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  • [Copyright] Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20307638.001).
  • [ISSN] 1872-7573
  • [Journal-full-title] Journal of ethnopharmacology
  • [ISO-abbreviation] J Ethnopharmacol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Anti-Inflammatory Agents; 0 / Inflammation Mediators; 0 / Lipopolysaccharides; 0 / Plant Extracts; 1HGW4DR56D / Leukotriene B4; 37H9VM9WZL / Calcimycin
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87. Motojima H, Yamada P, Han J, Ozaki M, Shigemori H, Isoda H: Properties of fulvic acid extracted from excess sludge and its inhibiting effect on beta-hexosaminidase release. Biosci Biotechnol Biochem; 2009 Oct;73(10):2210-6

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  • The biological properties of fulvic acid from excess sludge and solubilized excess sludge showed an inhibitory effect on beta-hexosaminidase release at the antigen-antibody binding stage and antigen-receptor binding stage by using rat basophilic leukemia cells.

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  • (PMID = 19809201.001).
  • [ISSN] 1347-6947
  • [Journal-full-title] Bioscience, biotechnology, and biochemistry
  • [ISO-abbreviation] Biosci. Biotechnol. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies; 0 / Benzopyrans; 0 / Sewage; EC 3.2.1.52 / beta-N-Acetylhexosaminidases; XII14C5FXV / fulvic acid
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88. Borges JP, Culerrier R, Aldon D, Barre A, Benoist H, Saurel O, Milon A, Didier A, Rougé P: GATEWAY technology and E. coli recombinant system produce a properly folded and functional recombinant allergen of the lipid transfer protein of apple (Mal d 3). Protein Expr Purif; 2010 Apr;70(2):277-82

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  • The reactivity of rMal d 3 towards IgE from apple allergic patients and in vitro degranulation activity measured on transformed rat basophil leukemia cells expressing the human Fc epsilon RI alpha-subunit of rMal d 3 is similar to those of the native allergen purified from apple fruits.

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  • [Copyright] (c) 2009 Elsevier Inc. All rights reserved.
  • (PMID = 19778615.001).
  • [ISSN] 1096-0279
  • [Journal-full-title] Protein expression and purification
  • [ISO-abbreviation] Protein Expr. Purif.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Allergens; 0 / Antigens, Plant; 0 / Carrier Proteins; 0 / Mal d 3 allergen; 0 / Recombinant Proteins; 0 / lipid transfer protein
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89. Blanc F, Bernard H, Alessandri S, Bublin M, Paty E, Leung SA, Patient KA, Wal JM: Update on optimized purification and characterization of natural milk allergens. Mol Nutr Food Res; 2008 Nov;52 Suppl 2:S166-75
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  • The purified proteins also demonstrated the ability to provoke the degranulation of humanized rat basophilic leukaemia cells.

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  • (PMID = 18504704.001).
  • [ISSN] 1613-4133
  • [Journal-full-title] Molecular nutrition & food research
  • [ISO-abbreviation] Mol Nutr Food Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Allergens; 0 / Caseins; 0 / Lactoglobulins; 9013-90-5 / Lactalbumin
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90. Curtis T, Naal RM, Batt C, Tabb J, Holowka D: Development of a mast cell-based biosensor. Biosens Bioelectron; 2008 Feb 28;23(7):1024-31
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  • Rat basophilic leukemia (RBL) mast cells offer excellent potential for biosensor applications because they are robust and undergo a dramatic exocytotic response within minutes of antigen addition.

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  • [Cites] Ann Biomed Eng. 1999 Nov-Dec;27(6):697-711 [10625143.001]
  • [Cites] Immunol Rev. 2007 Jun;217:269-79 [17498065.001]
  • [Cites] Immunol Lett. 2001 Jan 15;75(3):185-9 [11166374.001]
  • [Cites] J Immunol Methods. 2001 May 1;251(1-2):81-91 [11292484.001]
  • [Cites] Water Res. 2001 Jun;35(9):2207-18 [11358300.001]
  • [Cites] Trends Biotechnol. 2001 Aug;19(8):304-9 [11451472.001]
  • [Cites] Mol Biotechnol. 2001 Oct;19(2):125-31 [11725482.001]
  • [Cites] J Immunol. 2003 Dec 1;171(11):6119-27 [14634127.001]
  • [Cites] Biochim Biophys Acta. 2004 Mar 11;1697(1-2):39-51 [15023349.001]
  • [Cites] J Exp Med. 1974 Dec 1;140(6):1676-95 [4214891.001]
  • [Cites] Nature. 1975 Aug 7;256(5517):495-7 [1172191.001]
  • [Cites] Nature. 1978 Oct 26;275(5682):761-2 [703844.001]
  • [Cites] J Immunol. 1980 Feb;124(2):775-80 [7188700.001]
  • [Cites] J Immunol. 1980 Jun;124(6):2728-37 [7373045.001]
  • [Cites] Eur J Immunol. 1981 Apr;11(4):317-23 [6166481.001]
  • [Cites] Eur J Immunol. 1981 Jun;11(6):527-9 [6790293.001]
  • [Cites] J Biol Chem. 1984 Jun 10;259(11):7129-36 [6202691.001]
  • [Cites] J Biol Chem. 1989 Nov 25;264(33):19730-9 [2531141.001]
  • [Cites] Science. 1990 Sep 21;249(4975):1431-3 [1698311.001]
  • [Cites] Biochemistry. 1992 Jun 16;31(23):5350-6 [1534998.001]
  • [Cites] Nature. 1993 Jan 28;361(6410):315-25 [8381210.001]
  • [Cites] J Immunol. 1993 May 1;150(9):4072-83 [8473750.001]
  • [Cites] Immunol Today. 1993 May;14(5):222-6 [8517921.001]
  • [Cites] J Clin Invest. 1997 Jan 15;99(2):315-24 [9006000.001]
  • [Cites] Annu Rev Immunol. 1999;17:931-72 [10358778.001]
  • [Cites] Biosens Bioelectron. 2004 Nov 1;20(4):791-6 [15522594.001]
  • [Cites] Nat Methods. 2006 Nov;3(11):887-9 [17060912.001]
  • [Cites] Biosens Bioelectron. 2007 Feb 15;22(7):1205-17 [16934970.001]
  • [Cites] J Cell Sci. 2000 Nov;113 Pt 21:3839-50 [11034911.001]
  • (PMID = 18055192.001).
  • [ISSN] 0956-5663
  • [Journal-full-title] Biosensors & bioelectronics
  • [ISO-abbreviation] Biosens Bioelectron
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / AI022449-13; United States / NIAID NIH HHS / AI / R01 AI022449; United States / NIAID NIH HHS / AI / AI 22449; United States / NIAID NIH HHS / AI / R01 AI022449-13
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS40874; NLM/ PMC2269709
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91. Alvarez-Errico D, Sayós J, López-Botet M: The IREM-1 (CD300f) inhibitory receptor associates with the p85alpha subunit of phosphoinositide 3-kinase. J Immunol; 2007 Jan 15;178(2):808-16
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  • In the present study, immunoprecipitation analysis revealed that both the p85alpha subunit of PI3K and Src homology region 2 domain-containing phosphatase-1 could be recruited by IREM-1 in transfected cells as well as in the U937 monocytic leukemia cells, which constitutively express the receptor.
  • By assaying the ability of different IREM-1 mutants to regulate the secretion of beta-hexosaminidase induced via FcRepsilonI in rat basophilic leukemia cells, both Y205 and Y249 appeared crucial for IREM-1-mediated inhibition.
  • Remarkably, engagement of an IREM-1 mutant (Y(205,249,284)F), which did not recruit Src homology region 2 domain-containing phosphatase-1 and lost its inhibitory function, induced rat basophilic leukemia cell degranulation.

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  • (PMID = 17202342.001).
  • [ISSN] 0022-1767
  • [Journal-full-title] Journal of immunology (Baltimore, Md. : 1950)
  • [ISO-abbreviation] J. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Surface; 0 / CD300C protein, human; 0 / GRB2 Adaptor Protein; 0 / Membrane Glycoproteins; 0 / Protein Subunits; 0 / Receptors, IgE; 42HK56048U / Tyrosine; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 3.1.3.16 / Protein Phosphatase 1; EC 3.1.3.48 / Protein Tyrosine Phosphatase, Non-Receptor Type 6
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92. Parusel I, Kahl S, Braasch F, Glowacki G, Halverson GR, Reid ME, Schawalder A, Ortolan E, Funaro A, Malavasi F, Hardie D, Halder S, Buckley CD, Haag F, Koch-Nolte F: A panel of monoclonal antibodies recognizing GPI-anchored ADP-ribosyltransferase ART4, the carrier of the Dombrock blood group antigens. Cell Immunol; 2005 Jul-Aug;236(1-2):59-65
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  • The mAbs reacted weakly also with human umbilical vein endothelial cells and the basophilic leukemia KU-812.

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  • (PMID = 16168396.001).
  • [ISSN] 0008-8749
  • [Journal-full-title] Cellular immunology
  • [ISO-abbreviation] Cell. Immunol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL54459
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Cell Cycle Proteins; 0 / GML protein, human; 0 / GPI-Linked Proteins; 0 / Membrane Proteins; 0 / Neoplasm Proteins; EC 2.4.2.- / ADP Ribose Transferases; EC 2.4.2.31 / ART4 protein, human
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93. Linhart B, Hartl A, Jahn-Schmid B, Verdino P, Keller W, Krauth MT, Valent P, Horak F, Wiedermann U, Thalhamer J, Ebner C, Kraft D, Valenta R: A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination. J Allergy Clin Immunol; 2005 May;115(5):1010-6
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  • Immune responses to the hybrid molecule were studied in BALB/c mice and rat basophil leukemia assays.
  • IgG antibodies induced by vaccination with the hybrid blocked immediate allergic reactions, as demonstrated by rat basophil degranulation assays in a murine model of grass pollen allergy.

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  • (PMID = 15867859.001).
  • [ISSN] 0091-6749
  • [Journal-full-title] The Journal of allergy and clinical immunology
  • [ISO-abbreviation] J. Allergy Clin. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Allergens; 0 / Epitopes, B-Lymphocyte; 0 / Immunoglobulin G; 0 / Recombinant Fusion Proteins; 0 / Vaccines; 0 / Vaccines, DNA
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94. Edel JB, Wu M, Baird B, Craighead HG: High spatial resolution observation of single-molecule dynamics in living cell membranes. Biophys J; 2005 Jun;88(6):L43-5
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  • In this letter we describe a study in which we incubate rat basophilic leukemia cells with a fluorescently labeled cell membrane component on a surface containing zero-mode waveguides (ZMWs).

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  • [Cites] Biochem J. 2004 Jul 1;381(Pt 1):13-8 [15128287.001]
  • [Cites] Methods. 2003 Jan;29(1):74-85 [12543073.001]
  • [Cites] Cytometry. 1999 Jul 1;36(3):176-82 [10404965.001]
  • [Cites] Methods. 2003 Feb;29(2):142-52 [12606220.001]
  • [Cites] Inflamm Res. 1997 Sep;46(9):354-60 [9339391.001]
  • [Cites] Science. 2003 Jan 31;299(5607):682-6 [12560545.001]
  • (PMID = 15821167.001).
  • [ISSN] 0006-3495
  • [Journal-full-title] Biophysical journal
  • [ISO-abbreviation] Biophys. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carbocyanines; 0 / Fluorescent Dyes; 40957-95-7 / 3,3'-dioctadecylindocarbocyanine
  • [Other-IDs] NLM/ PMC1305672
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95. Aneiros E, Philipp S, Lis A, Freichel M, Cavalié A: Modulation of Ca2+ signaling by Na+/Ca2+ exchangers in mast cells. J Immunol; 2005 Jan 1;174(1):119-30
The Lens. Cited by Patents in .

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  • Using rat basophilic leukemia (RBL) mast cells and murine bone marrow-derived mast cells, we examine the role of Na(+)/Ca(2+) exchangers.

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  • (PMID = 15611234.001).
  • [ISSN] 0022-1767
  • [Journal-full-title] Journal of immunology (Baltimore, Md. : 1950)
  • [ISO-abbreviation] J. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Sodium-Calcium Exchanger
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96. Jala VR, Shao WH, Haribabu B: Phosphorylation-independent beta-arrestin translocation and internalization of leukotriene B4 receptors. J Biol Chem; 2005 Feb 11;280(6):4880-7
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  • These mutants expressed in rat basophilic leukemia RBL-2H3 cells bound LTB4 with similar affinity and activated all of the known functional activities of BLT1, albeit at different levels.

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  • (PMID = 15561704.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / AI-43184; United States / NIAID NIH HHS / AI / AI-52381
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Arrestins; 0 / Epitopes; 0 / Ligands; 0 / Receptors, Leukotriene B4; 0 / beta-arrestin; 147336-22-9 / Green Fluorescent Proteins; EC 3.2.1.52 / beta-N-Acetylhexosaminidases; OF5P57N2ZX / Alanine; SY7Q814VUP / Calcium
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97. Kim Y, Eom S, Kim K, Lee YS, Choe J, Hahn JH, Lee H, Kim YM, Ha KS, Ro JY, Jeoung D: Transglutaminase II interacts with rac1, regulates production of reactive oxygen species, expression of snail, secretion of Th2 cytokines and mediates in vitro and in vivo allergic inflammation. Mol Immunol; 2010 Feb;47(5):1010-22
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  • Antigen stimulation induced expression and activity of TGase II by activation of NF-kappaB in rat basophilic leukemia (RBL2H3) cells.

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  • [Copyright] (c) 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 20004474.001).
  • [ISSN] 1872-9142
  • [Journal-full-title] Molecular immunology
  • [ISO-abbreviation] Mol. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens; 0 / Cadherins; 0 / Carcinogens; 0 / Cytokines; 0 / NF-kappa B; 0 / Neuropeptides; 0 / Rac1 protein, mouse; 0 / Reactive Oxygen Species; EC 2.3.2.- / transglutaminase 2; EC 2.3.2.13 / Transglutaminases; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.5.1.98 / Histone Deacetylases; EC 3.5.1.98 / histone deacetylase 3; EC 3.6.1.- / GTP-Binding Proteins; EC 3.6.1.- / Rac1 protein, rat; EC 3.6.5.2 / rac GTP-Binding Proteins; EC 3.6.5.2 / rac1 GTP-Binding Protein; EC 5.3.- / Intramolecular Oxidoreductases; EC 5.3.99.3 / prostaglandin-E synthase; K7Q1JQR04M / Dinoprostone; NI40JAQ945 / Tetradecanoylphorbol Acetate
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98. Blanc F, Adel-Patient K, Drumare MF, Paty E, Wal JM, Bernard H: Capacity of purified peanut allergens to induce degranulation in a functional in vitro assay: Ara h 2 and Ara h 6 are the most efficient elicitors. Clin Exp Allergy; 2009 Aug;39(8):1277-85

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  • OBJECTIVES: We optimized an in vitro functional assay to assess the capacity of peanut allergens to degranulate humanized rat basophilic leukaemia cells, RBL SX-38 cells, after sensitization by serum IgE from peanut-allergic patients.
  • [MeSH-major] 2S Albumins, Plant / immunology. Allergens / immunology. Antigens, Plant / immunology. Basophil Degranulation Test. Glycoproteins / immunology. Peanut Hypersensitivity / immunology

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  • (PMID = 19538351.001).
  • [ISSN] 1365-2222
  • [Journal-full-title] Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • [ISO-abbreviation] Clin. Exp. Allergy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 2S Albumins, Plant; 0 / Allergens; 0 / Antigens, Plant; 0 / Ara h 2 allergen, Arachis hypogaea; 0 / Ara h 6 allergen, Arachis hypogaea; 0 / Glycoproteins; 0 / Receptors, IgE; 37341-29-0 / Immunoglobulin E
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99. Chen BH, Wu PY, Chen KM, Fu TF, Wang HM, Chen CY: Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger). J Nat Prod; 2009 May 22;72(5):950-3
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  • In the present study on five pure phenolic compounds (1-5) isolated from the rhizomes of Zingiber officinale (ginger) and investigated for their antiallergic potency, rat basophilic leukemia (RBL-2H3) cells were incubated with these compounds and the release of beta-hexosaminidase was measured kinetically.

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  • (PMID = 19271742.001).
  • [ISSN] 1520-6025
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Allergic Agents; 0 / Phenols
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100. Lim H, Son KH, Chang HW, Bae K, Kang SS, Kim HP: Anti-inflammatory activity of pectolinarigenin and pectolinarin isolated from Cirsium chanroenicum. Biol Pharm Bull; 2008 Nov;31(11):2063-7
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  • In order to identify the active anti-inflammatory ingredient(s) in Cirsium chanroenicum (Compositae), its methanol extract and several solvent fractions were prepared; the methanol extract and the ethylacetate fraction inhibited cyclooxygenase-2 (COX-2)-mediated prostaglandin E2 (PGE2) and 5-lipoxygenase (5-LOX)-mediated leukotriene (LT) production in lipopolysaccharide-treated RAW 264.7 cells and A23187-treated rat basophilic leukemia (RBL-1) cells, respectively.

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  • (PMID = 18981574.001).
  • [ISSN] 0918-6158
  • [Journal-full-title] Biological & pharmaceutical bulletin
  • [ISO-abbreviation] Biol. Pharm. Bull.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Chromones; 0 / Leukotrienes; 0 / NF-kappa B; 0 / pectolinarigenin; 28978-02-1 / pectolinarin; EC 1.13.11.34 / Arachidonate 5-Lipoxygenase; EC 1.14.99.1 / Cyclooxygenase 2; K7Q1JQR04M / Dinoprostone
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