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1. Loh JK, Hwang SL, Tsai KB, Kwan AL, Howng SL: Sphenoid ridge lymphoplasmacyte-rich meningioma. J Formos Med Assoc; 2006 Jul;105(7):594-8
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for lymphoplasmacyte-rich meningioma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sphenoid ridge lymphoplasmacyte-rich meningioma.
  • There are numerous histologic variants of meningioma.
  • Among the more uncommon are intracranial masses composed of meningiomatous and plasma cell-lymphocytic elements.
  • We report a 22-year-old woman with lymphoplasmacyte-rich meningioma who initially presented with dizziness and progressive headache.
  • Neuroradiologic images revealed typical meningiomas of the sphenoid ridge with extensive perifocal edema.
  • Complete macroscopic removal of the tumor was performed.
  • Histologic examination revealed a meningioma with massive infiltrates of plasma cells and lymphocytes.
  • Brain computed tomography on the 6th postoperative day revealed total removal of the tumor with marked reduction of brain edema.
  • Complete resolution of symptoms occurred with no evidence of tumor recurrence during 2 years of follow-up.

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  • (PMID = 16877241.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Singapore
  • [Number-of-references] 19
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2. Nohara H, Furuya K, Kawahara N, Iijima A, Yako K, Shibahara J, Kirino T: Lymphoplasmacyte-rich meningioma with atypical invasive nature. Neurol Med Chir (Tokyo); 2007 Jan;47(1):32-5
Genetic Alliance. consumer health - Meningioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoplasmacyte-rich meningioma with atypical invasive nature.
  • A 12-year-old boy presented with a lymphoplasmacyte-rich (LPR) meningioma in the posterior fossa.
  • The tumor was subtotally removed.
  • Histological examination showed the tumor had invaded the normal brain tissue despite its benign grade in the World Health Organization classification.
  • The Ki-67 staining index using MIB-1 monoclonal antibody was relatively high. (18)F-2-fluoro-2-deoxy-D-glucose positron emission tomography revealed high uptake in the tumor.
  • These findings indicate the atypical nature of LPR meningioma.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology. Plasma Cells
  • [MeSH-minor] Adolescent. Humans. Male. Neoplasm Invasiveness

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  • (PMID = 17245013.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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3. García-Purriños FJ, Rosell Cervilla A, Lemberg P, Calvo Moya J: [Nasal malignant meningioma]. Acta Otorrinolaringol Esp; 2005 Oct;56(8):373-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Nasal malignant meningioma].
  • [Transliterated title] Meningioma maligno nasal. manejo de un caso y revisión de la literatura.
  • Extracraneal meningiomas represent 2% of all meningiomas and can appear in different locations including paranasales sinuses.
  • There are no statistics regarding ectopic malignant meningiomas, but they are considered extremely rare.
  • We present a patient with a malignant meningioma of the etmoidal sinus, his treatment and the evolution over a five year period.
  • [MeSH-major] Meningioma / pathology. Nose Neoplasms / pathology

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  • (PMID = 16285437.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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4. Marcelissen TA, de Bondt RB, Lammens M, Manni JJ: Primary temporal bone secretory meningioma presenting as chronic otitis media. Eur Arch Otorhinolaryngol; 2008 Jul;265(7):843-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary temporal bone secretory meningioma presenting as chronic otitis media.
  • We report an extremely rare case of a secretory meningioma primarily involving the temporal bone.
  • Diagnostic investigations revealed a tumor arising from the temporal bone without signs of intracranial involvement.
  • Histopathological examination showed a meningioma of the secretory type.
  • The tumor was partially resected and serial imaging at follow-up revealed no extension of the tumor.
  • Secretory meningioma is a rare meningioma subtype and extracranial presentation in the temporal bone is very unusual.
  • We present the first case of a primary temporal bone secretory meningioma in the otorhinolaryngological literature.
  • [MeSH-major] Meningeal Neoplasms / complications. Meningeal Neoplasms / pathology. Meningioma / complications. Meningioma / pathology. Otitis Media with Effusion / diagnosis. Otitis Media with Effusion / etiology. Temporal Lobe / pathology
  • [MeSH-minor] Audiometry, Pure-Tone. Chronic Disease. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Middle Aged

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  • [Cites] Laryngoscope. 1983 Nov;93(11 Pt 1):1397-404 [6633109.001]
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  • (PMID = 18172659.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2440930
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5. Marrero CL, Domínguez J, Ramos R, Gómez J, Lourido JA: [Intraventricular meningioma: case report in infancy]. Neurocirugia (Astur); 2005 Dec;16(6):523-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intraventricular meningioma: case report in infancy].
  • [Transliterated title] Meningioma intraventricular. Presentación de un caso en la infancia
  • Meningiomas are infrequent tumours in infancy but when they appear in this age group, the intraventricular location is more frequent than in adults.
  • We report the case of a 5-year-old girl with intracranial hypertension and a VI nerve palsy.
  • Computed tomography and magnetic resonance imaging of the brain revealed a tumoral lesion involving the right lateral ventricle with intense enhancement after contrast administration.
  • Histological diagnosis was of atypical meningioma.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Lateral Ventricles / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis

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  • (PMID = 16378135.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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6. Arias Marzán F, de Lucas Carmona G, Alvarez Flórez M, Febles García P: [Extracranial meningiomas of the paranasal sinuses]. Acta Otorrinolaringol Esp; 2010 May-Jun;61(3):238-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Extracranial meningiomas of the paranasal sinuses].
  • [Transliterated title] Meningioma primario extracraneal de senos paranasales.
  • Extracraneal meningiomas are infrequent and their localization in the paranasal sinuses is rare.
  • We present the case of a patient with a primary meningioma of the paranasal sinuses.
  • [MeSH-major] Meningioma. Paranasal Sinus Neoplasms

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  • [Copyright] Copyright 2009 Elsevier España, S.L. All rights reserved.
  • (PMID = 20452881.001).
  • [ISSN] 1988-3013
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 21
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7. Arrese T, González P, Ramos A, Ruiz J, Lobato RD: [Idiopathic hypertrophic pachymeningitis of the cavernous sinus mimicking meningioma with complete occlusion of the carotid artery]. Neurocirugia (Astur); 2005 Feb;16(1):63-6
MedlinePlus Health Information. consumer health - Meningitis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Idiopathic hypertrophic pachymeningitis of the cavernous sinus mimicking meningioma with complete occlusion of the carotid artery].
  • [Transliterated title] Paquimeningitis crónica hipertrófica del seno cavernoso simulando meningioma con oclusión completa de la arteria carótida.
  • We present the case of a patient with IHPM who was diagnosed of meningioma and showed a complete occlusion of the intracavernous carotid artery.
  • This 42 years old woman was sent to our hospital to be treated radiosurgicaly with the diagnosis of meningioma.
  • The diagnosis was based on MRI findings and on the temporal resistance to corticoid treatment.
  • The differential diagnosis between meningioma and IHPM may be complex because of the similarities in image findings and the temporal resistance to corticosteroids shown by IHPM, thus we emphasize the usefulness of the SPECT to differentiate between inflammation and tumor in this clinical setting.
  • In addition, our patient showed a total occlusion of the intracavernous carotid artery and, as far as we know, this is the first case with such a finding reported in the literature.
  • [MeSH-major] Cavernous Sinus / metabolism. Cavernous Sinus / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Meningitis / diagnosis
  • [MeSH-minor] Adult. Anti-Inflammatory Agents / therapeutic use. Brain / pathology. Brain / radionuclide imaging. Carotid Stenosis / diagnosis. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Tomography, Emission-Computed, Single-Photon

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  • (PMID = 15756414.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents
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8. Mattozo CA, De Salles AA, Klement I, Gorgulho AA, Cabatan-Awang C, Timothy S, Selch M: 821 Stereotactic Radiation for Aggressive Meningiomas According to the WHO 2000 Classification. Neurosurgery; 2005 Aug 01;57(2):402

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 821 Stereotactic Radiation for Aggressive Meningiomas According to the WHO 2000 Classification.

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  • (PMID = 28184766.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Natarajan SK, Sekhar LN, Wright DC, Farrokhi F, Schessel D: Patients' Outcome at Long-term Follow-up after Aggressive Microsurgical Resection of Petroclival Meningiomas 905. Neurosurgery; 2006 Aug 01;59(2):489

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Patients' Outcome at Long-term Follow-up after Aggressive Microsurgical Resection of Petroclival Meningiomas 905.

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  • (PMID = 28180743.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Aghi MK, Curry WT, Carter B, Barker FG: High Incidence of Obesity and Obesity-related Postoperative Complications in Male Patients with Meningiomas 900. Neurosurgery; 2006 Aug 01;59(2):487-488

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High Incidence of Obesity and Obesity-related Postoperative Complications in Male Patients with Meningiomas 900.

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  • (PMID = 28180725.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Danish SF, Zager EL: Cervical Spine Meningioma Presenting as Otalgia: Case Report. Neurosurgery; 2005 Mar 01;56(3):E621

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cervical Spine Meningioma Presenting as Otalgia: Case Report.

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  • (PMID = 28184664.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Nakamura M, Roser F, Jacobs C, Vorkapic P, Samii M: Medial Sphenoid Wing Meningiomas. Neurosurgery; 2006 Apr 01;58(4):626-639

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Medial Sphenoid Wing Meningiomas.

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  • (PMID = 28180543.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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13. Henzel M, Gross MW, Hamm K, Surber G, Kleinert G, Failing T, Strassmann G, Engenhart-Cabillic R: Significant Tumorvolume Reduction Of Meningiomas Afterstereotactic Radiotherapy: Results Of A Prospective Multicenter Study. Neurosurgery; 2006 Dec 01;59(6):1188-1194

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Significant Tumorvolume Reduction Of Meningiomas Afterstereotactic Radiotherapy: Results Of A Prospective Multicenter Study.

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  • (PMID = 28180780.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Colombo F, Casentini L, Cavedon C, Scalchi P, Cora S, Francescon P: Cyberknife Radiosurgery for Benign Meningiomas: Short-term Results in 199 Patients. Neurosurgery; 2009 Feb 01;64(suppl_2):A7-A13

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cyberknife Radiosurgery for Benign Meningiomas: Short-term Results in 199 Patients.

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  • (PMID = 28173326.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Ketter R: Correspondence of Tumor Localization with Tumor Recurrence and Cytogenetic Progression in Meningiomas. Neurosurgery; 2009 Jun 01;64(6):E1206

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correspondence of Tumor Localization with Tumor Recurrence and Cytogenetic Progression in Meningiomas.

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  • (PMID = 28173325.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Jouanneau E, Tovar RA, Desuzinges C, Frappaz D, Louis-Tisserand G, Sunyach MP, Jouvet A, Sindou M: Very Late Frontal Relapse of Medulloblastoma Mimicking a Meningioma in an Adult. Neurosurgery; 2006 Apr 01;58(4):E789

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Very Late Frontal Relapse of Medulloblastoma Mimicking a Meningioma in an Adult.

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  • (PMID = 28180554.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Tlachacova D, Schmitt M, Novotny J Jr, Novotny J, Majali M, Liscak R: A comparison of the gamma knife model C and the Automatic Positioning System with Leksell model B. J Neurosurg; 2005 Jan;102(s_supplement):25-28

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Data were analyzed in patients in whom the following diagnoses had been made: vestibular schwannoma, pituitary adenoma, meningioma, solitary metastasis, and other benign and malignant solitary tumors.
  • CONCLUSIONS: With the C model there was a better conformity for most treated targets, such as vestibular schwannomas (p = 0.005) and meningiomas (p = 0.015).

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  • (PMID = 28306471.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; conformity index / extracranial exposure / staff exposure / stereotactic radiosurgery
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18. Saavedra D, Guevara-Salazar P, Escobar-Arriaga E, Martinez-Rumayor A, Rembao D, Calderon A, Sotelo J, Arrieta O: Angiogenesis and expression of estrogen and progesterone receptors as predictive factors of recurrence in meningiomas: A long-term prospective study. J Clin Oncol; 2009 May 20;27(15_suppl):e13013

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiogenesis and expression of estrogen and progesterone receptors as predictive factors of recurrence in meningiomas: A long-term prospective study.
  • : e13013 Background: Meningioma is a bening tumor, with a high rate of recurrence after surgery (80%); the most important relapse predictive factor is the extent of surgical resection; other potentially predictive factors have been studied with poor results.
  • Angiogenesis has an important role in growth and spread of neoplasic cells; previous studies have shown a high incidence of cyclin E (CE), estrogen, and progesterone receptors (ER, PR) in meningiomas.
  • The aim of this prospective study was to evaluate the prognostic significance of clinical-pathological factors (CPF), vascular density index (VDI), cell proliferation index (CPI), CE, ER, and PR tissue expression in meningioma recurrence of patients submitted to surgical resection.
  • METHODS: From January 1995 to December 2000, we enrolled 42 patients with histopathological diagnosis of meningioma and treated only with surgical resection.
  • Tumor VDI, CPI, CE, ER, and PR tissue expression were evaluated by immunohistochemistry in patients with or without recurrence.
  • Recurrence of meningioma was found in 17 patients (40%).
  • CONCLUSIONS: Patients with partially resected meningioma and high VDI have an increased recurrence risk and could benefit of additional therapeutic measures.

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  • (PMID = 27962822.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Huffmann BC, Reinacher PC, Gilsbach JM: Gamma knife surgery for atypical meningiomas. J Neurosurg; 2005 Jan;102(s_supplement):283-286

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gamma knife surgery for atypical meningiomas.
  • OBJECT: Complete resection is the optimal treatment for atypical meningiomas (AMs) but its feasibility depends on the tumor site.
  • Four patients had residual lesions and 10 patients had recurrent tumors after one or more microsurgical interventions.
  • Three patients were treated twice with GKS because of tumor tissue outside the treatment volume, either at the margin or at a distant location.
  • Ten tumors shrank 6 to 12 months after GKS, 10 remained stable, and one grew.
  • CONCLUSIONS: After early tumor shrinkage, high recurrence rates were demonstrated both at the treatment margin and at distant locations in cases treated for AM.

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  • (PMID = 28306448.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; atypical meningioma / gamma knife surgery / radiosurgery
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20. Shehaby AE, Ganz JC, Reda WA, Hafez A: Temporary symptomatic swelling of meningiomas following gamma knife surgery. J Neurosurg; 2005 Jan;102(s_supplement):293-296

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Temporary symptomatic swelling of meningiomas following gamma knife surgery.
  • ✓ In two patients in whom gamma knife surgery was performed for meningiomas clinically significant volume increases were observed in the first 3 months after treatment.

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  • (PMID = 28306463.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; complication / dexamethasone / meningioma / tumor swelling
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21. Norden AD, Raizer JJ, Lamborn KR, Abrey LE, Chang SM, Gilbert MR, Cloughesy TF, Prados MD, Lieberman F, Wen P: Phase II trials of erlotinib or gefitinib in patients with recurrent meningiomas. J Clin Oncol; 2009 May 20;27(15_suppl):2062

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase II trials of erlotinib or gefitinib in patients with recurrent meningiomas.
  • : 2062 Background: No effective treatment is available for recurrent meningiomas when surgical and radiation options are exhausted.
  • The epidermal growth factor receptor (EGFR) is often over-expressed in meningiomas and may promote tumor growth.
  • In open label, single arm phase II studies of the EGFR inhibitors gefitinib (NABTC 00-01) and erlotinib (NABTC 01-03) for recurrent malignant gliomas, we included exploratory subsets of recurrent meningioma patients.
  • METHODS: Patients with recurrent histologically confirmed meningiomas and no more than two previous chemotherapy regimens were treated with gefitinib 500 mg/day or erlotinib 150 mg/day until tumor progression or unacceptable toxicity.
  • Eight patients (32%) had benign tumors, 9 (36%) atypical, and eight (32%) malignant.
  • For benign tumors, the 6-month progression-free survival (PFS6) was 29%, 12-month PFS (PFS12) 0%, 6-month overall survival (OS6) 63%, and 12-month OS (OS12) 50%.
  • For atypical/malignant tumors, PFS6 was 25%, PFS12 19%, OS6 81%, and OS12 68%.
  • Of 21 evaluable patients, there were no responses; eight patients (38%) had stable disease, and 13 (62%) had progressive disease.
  • CONCLUSIONS: Neither gefitinib nor erlotinib appear to have significant activity against recurrent meningioma.
  • The role of EGFR inhibitors in meningiomas is unclear but evaluation of EGFR inhibitors in combination with other targeted molecular agents may be warranted.

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  • (PMID = 27964693.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Shuto T, Inomori S, Fujino H, Nagano H, Hasegawa N, Kakuta Y: Cyst formation following gamma knife surgery for intracranial meningioma. J Neurosurg; 2005 Jan;102(s_supplement):134-139

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cyst formation following gamma knife surgery for intracranial meningioma.
  • OBJECT: The authors conducted a study to evaluate the clinical significance of cyst formation or enlargement after gamma knife surgery (GKS) for intracranial benign meningiomas.
  • METHODS: The medical records of 160 patients with 184 tumors were examined for those with follow-up data of more than 2 years among 270 patients who underwent GKS for intracranial meningiomas between February 1992 and November 2001.
  • The tumor location was the sphenoid ridge in one case, petroclival in two, tentorium in one, and parasagittal region in one.
  • The mean tumor volume was 10.5 cm<sup>3</sup>, the mean margin dose was 13.4 Gy (median 14 Gy), and the mean maximum dose was 27.5 Gy (median 24.1 Gy).
  • At the time of GKS three tumors were associated with cyst, of which two enlarged after radiosurgery.
  • Histological examination demonstrated various findings such as tumor necrosis, proliferation of small vessels, vascular obliteration, and hemosiderin deposits.
  • CONCLUSIONS: New cyst formation following GKS for benign intracranial meningioma is relatively rare; however, both preexisting and newly developed cysts tend to enlarge after GKS and often require surgery.

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  • (PMID = 28306456.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; cyst / gamma knife surgery / meningioma
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23. Taking contraceptive pill may increase meningioma risk. Nurs Stand; 2010 Oct 20;25(7):17

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Taking contraceptive pill may increase meningioma risk.
  • : Use of exogenous hormones, especially current use, appears to increase the risk of meningioma, but is not associated with glioma.

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  • (PMID = 28019590.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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24. Linskey ME, Davis SA, Ratanatharathorn V: Relative roles of microsurgery and stereotactic radiosurgery for the treatment of patients with cranial meningiomas: a single-surgeon 4-year integrated experience with both modalities. J Neurosurg; 2005 Jan;102(s_supplement):59-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relative roles of microsurgery and stereotactic radiosurgery for the treatment of patients with cranial meningiomas: a single-surgeon 4-year integrated experience with both modalities.
  • OBJECT: The authors sought to assess the respective roles of microsurgery and gamma knife surgery (GKS) in the treatment of patients with meningiomas.
  • METHODS: The authors culled from a 4-year prospective database data on 74 cases of meningiomas.
  • The mean tumor coverage was 94.7%, and the mean conformity index was 1.76.
  • Significant differences between the two treatment groups (GKS compared with microsurgery) included age (mean 60 compared with 50.7 years), volume (mean 7.85 cm<sup>3</sup> compared with 44.4 cm<sup>3</sup>), treatment history (55.3% compared with 14.3%), and tumor location (cavernous sinus/petroclival, 14 compared with three).
  • In patients with benign meningiomas GKS tumor control was 96.8% with one recurrence at the margin.
  • CONCLUSIONS: Both GKS and microsurgery serve important roles in the overall management of patients with meningiomas.

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  • (PMID = 28306454.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / meningioma / microsurgery / skull base surgery / stereotaxy
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25. Feigl GC, Bundschuh O, Gharabaghi A, Samii M, Horstmann GA: Volume reduction in meningiomas after gamma knife surgery. J Neurosurg; 2005 Jan;102(s_supplement):189-194

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Volume reduction in meningiomas after gamma knife surgery.
  • OBJECT: The purpose of this study was to evaluate the volume-reducing effects of gamma knife surgery (GKS) of meningiomas with and without previous surgical treatment.
  • METHODS: A group of 127 patients with a mean age of 57.1 years (range 9-81 years) with 142 meningiomas (128 World Health Organization Grade I and 14 Grade II) were included in this study.
  • The management strategy reduces tumor volume with surgery when necessary (81 patients).
  • Stereotactic GKS with a Gamma Knife model C was performed in all tumors of suitable size.
  • Magnetic resonance imaging follow-up examinations with volumetric tumor analysis was performed 6 months after treatment and annually thereafter.
  • The mean tumor volume was 5.9 cm<sup>3</sup> (range < 5 to > 40 cm<sup>3</sup>).
  • A reduction in volume occurred in 117 (82.4%) of all tumors, and in 20 tumors (14.1%) growth ceased.
  • The overall tumor control rate of 96.4%.
  • Only five tumors (3.5%) showed a volume increase.
  • CONCLUSIONS: Gamma knife surgery was effective in reducing meningioma volume at short-term follow up.

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  • (PMID = 28306469.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife / meningioma / radiosurgery / tumor control / volume reduction
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26. Kwon Y, Bae JS, Kim JM, Lee DH, Kim SY, Ahn JS, Kim JH, Kim CJ, Kwun BD, Lee JK: Visual changes after gamma knife surgery for optic nerve tumors. J Neurosurg; 2005 Jan;102(s_supplement):143-146

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Visual changes after gamma knife surgery for optic nerve tumors.
  • Tumors involving the optic nerve (optic glioma, optic nerve sheath meningioma) are benign but difficult to treat.

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  • (PMID = 28306473.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / optic glioma / optic nerve sheath meningioma
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27. Shehaby AE, Ganz JC, Reda WA, Hafez A: Mechanisms of edema after gamma knife surgery for meningiomas. J Neurosurg; 2005 Jan;102(s_supplement):1-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mechanisms of edema after gamma knife surgery for meningiomas.
  • ✓ The authors describe two patients in whom tumor swelling and brain swelling (and possible tumor swelling), respectively, developed after undergoing gamma knife surgery.
  • One had a skull defect with a palpable parasagittal tumor.
  • One had neurofibromatosis Type 2 with multiple tumors, one of which was parasagittal.

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  • (PMID = 28306444.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; complications / dexamethasone / gamma knife surgery / meningioma
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28. Kim DG, Kim CH, Chung HT, Paek SH, Jeong SS, Han DH, Jung HW: Gamma knife surgery of superficially located meningioma. J Neurosurg; 2005 Jan;102(s_supplement):255-258

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gamma knife surgery of superficially located meningioma.
  • OBJECT: The authors analyzed tumor control rates and complications in patients with superficially located meningiomas after gamma knife surgery (GKS).
  • The median tumor volume was 4.7 cm<sup>3</sup>, and the mean margin dose was 16 Gy at the 50% isodose line.
  • The tumor shrank in eight cases, was stable in 17, and enlarged in one; thus 25 (95%) of 26 tumors were controlled.
  • High signal was associated with a high integral dose and a large tumor volume.
  • Tumor shrinkage at the last follow-up examination was more prominent in the patients with symptomatic high signal (p = 0.03).
  • CONCLUSIONS: There was a good tumor control rate with a high complication rate.

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  • (PMID = 28306457.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; edema / gamma knife surgery / meningioma / peritumoral / superficial
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29. Swinnen LJ, Rankin C, Rushing EJ, Laura HF, Damek DM, Barger GR: Phase II study of hydroxyurea for unresectable meningioma (Southwest Oncology Group S9811). J Clin Oncol; 2009 May 20;27(15_suppl):2063

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase II study of hydroxyurea for unresectable meningioma (Southwest Oncology Group S9811).
  • : 2063 Background: Meningiomas account for 15%-18% of CNS tumors.
  • Tumor location may make further resection hazardous.
  • Induction of apoptosis was furthermore demonstrated with HU in primary benign meningioma explant cultures.
  • The S9811 phase II trial was undertaken to estimate the objective response rate, if any, of unresectable benign meningioma to this HU regimen.
  • METHODS: Eligibility required unresectable, measurable, residual or recurrent, histologically-proven benign meningioma.
  • Progressive tumor or progressive neurologic deficit was required.
  • HU 20 mg/kg/day po was given for up to 2 years if there was no progressive disease.
  • Response assessment showed CR+PR 0% (95% CI 0-12%); SD 71% (95% CI 51-87%); PD 21% (95% CI 8-41%); undetermined 7%.
  • CONCLUSIONS: Chronic HU therapy for unresectable benign meningioma resulted in an estimated objective response rate of < 12%.
  • Whether the stable disease rate seen differs in any way from what can be expected from the natural history of meningioma cannot be determined from this phase II study design.

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  • (PMID = 27964694.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Hosler MR, Turbin RE, Cho ES, Wolansky LJ, Frohman LP: Idiopathic hypertrophic pachymeningitis mimicking lymphoplasmacyte-rich meningioma. J Neuroophthalmol; 2007 Jun;27(2):95-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Idiopathic hypertrophic pachymeningitis mimicking lymphoplasmacyte-rich meningioma.
  • A 28-year-old woman with a 6-year history of optic neuropathy and 8 years of hearing loss had enhancing dural lesions around the brain stem and in both internal auditory canals on MRI.
  • Histopathology from cranial procedures performed in 1990 and 1993 was originally interpreted as inflammatory meningioma, now known as lymphoplasmacyte-rich meningioma (LRM).
  • The review led to a pathologic diagnosis of idiopathic hypertrophic pachymeningitis (IHP).
  • [MeSH-major] Dura Mater / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Meningitis / diagnosis. Plasma Cells / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Hypertrophy. Magnetic Resonance Imaging

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  • [CommentIn] J Neuroophthalmol. 2007 Jun;27(2):89-90 [17548989.001]
  • (PMID = 17548991.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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31. Shivane AG, Chakrabarty A, Baborie A, Thiryayi W, Donaldson MH, Ross S: A rare case of recurrent secretory meningioma with malignant transformation. Br J Neurosurg; 2006 Aug;20(4):250-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of recurrent secretory meningioma with malignant transformation.
  • A 72-year-old woman previously operated for a sphenoid-ridge meningioma, now presented with double vision.
  • Histology showed a secretory meningioma with an epithelial-appearing, malignant component.
  • Malignant transformation in a secretory meningioma is not known.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 16954080.001).
  • [ISSN] 0268-8697
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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32. Avninder S, Gupta V, Sharma KC: Lymphoplasmacyte-rich meningioma at the foramen magnum. Br J Neurosurg; 2008 Oct;22(5):702-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoplasmacyte-rich meningioma at the foramen magnum.
  • We report a case of lymphoplasmacyte-rich meningioma (LPM) in a 22-year-old woman who presented with headache, hemiparesis and hypoaesthesia.
  • MRI revealed a meningioma at the foramen magnum region that was resected by far-lateral approach.
  • [MeSH-major] Foramen Magnum / pathology. Lymphocytes / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology

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  • (PMID = 18661316.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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33. Ghosal N, Furtado SV, Santosh V, Sridhar M, Hegde AS: Co-existing fibrous dysplasia and atypical lymphoplasmacyte-rich meningioma. Neuropathology; 2007 Jun;27(3):269-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Co-existing fibrous dysplasia and atypical lymphoplasmacyte-rich meningioma.
  • We report an unusual and extremely rare case of coexisting fibrous dysplasia of the sphenoid sinus with atypical lymphoplasmacyte rich meningioma (World Health Organization Grade II), right frontal lobe in a 25-year-old male.
  • On histopathology the frontal lobe lesion showed a tumor composed of cells with vesicular nuclei, focal nuclear pleomorphism, a mitotic rate of = 4/10 high power field and a single focus of necrosis.
  • Although no definite causative factors are described for the coexistence of these tumors, however, a common yet undetermined denominator in the origin has been proposed in the literature.
  • [MeSH-major] Fibrous Dysplasia, Monostotic / complications. Fibrous Dysplasia, Monostotic / pathology. Meningeal Neoplasms / complications. Meningeal Neoplasms / pathology. Meningioma / complications. Meningioma / pathology

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  • (PMID = 17645241.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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34. Cenacchi G, Ferri GG, Salfi N, Tarantino L, Modugno GC, Ceroni AR, Martinelli GN: Secretory meningioma of the middle ear: a light microscopic, immunohistochemical and ultrastructural study of one case. Neuropathology; 2008 Feb;28(1):69-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secretory meningioma of the middle ear: a light microscopic, immunohistochemical and ultrastructural study of one case.
  • A probable diagnosis of left secretory otitis media with effusion was formulated.
  • The histopathologic, immunohistochemical and ultrastructural response was secretory meningioma, a rare variant of conventional meningothelial meningioma in atypical sites.
  • [MeSH-major] Ear, Middle / ultrastructure. Meningeal Neoplasms / ultrastructure. Meningioma / ultrastructure
  • [MeSH-minor] Aged. Carcinoembryonic Antigen / metabolism. Diagnosis, Differential. Female. Hearing Loss / etiology. Humans. Immunohistochemistry. Mucin-1 / metabolism. Otitis Media / pathology. Tomography, X-Ray Computed

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  • (PMID = 18181836.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Mucin-1
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35. Ferchichi L, Bellil S, Ben Hammouda K, Bellil K, Mekni A, Bettaieb I, Haouet S, Khaldi MM, Zitouna K, Kchir N: Anaplastic secretory meningioma: a case report. Pathologica; 2006 Apr;98(2):153-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anaplastic secretory meningioma: a case report.
  • Secretory meningiomas are rare histological subtypes of meningiomas with benign biological behaviour.
  • In this study, the authors describe the first case of secretory meningioma with many mitotic figures and brain invasion, and discuss the clinicopathologic features including immunohistochemical staining profile and ultrastructural appearance of this tumour.
  • A case of a 54-year-old man diagnosed with an intracranial tumour located in the left frontal lobe is presented.
  • The histological diagnosis was secretory meningioma with many mitotic figures, a high MIB-1 labeling index and a brain invasion.
  • [MeSH-major] Frontal Lobe / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Carcinoembryonic Antigen / analysis. Combined Modality Therapy. Cranial Irradiation. Humans. Keratins / analysis. Ki-67 Antigen / analysis. Male. Middle Aged. Mitotic Index. Mucin-1 / analysis. Neoplasm Invasiveness. Neoplasm Proteins / analysis. Neoplasm Recurrence, Local / radiotherapy. Radiotherapy, Adjuvant

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  • (PMID = 16929789.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Ki-67 Antigen; 0 / Mucin-1; 0 / Neoplasm Proteins; 68238-35-7 / Keratins
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36. Marosi C, Hassler M, Roessler K, Reni M, Sant M, Mazza E, Vecht C: Meningioma. Crit Rev Oncol Hematol; 2008 Aug;67(2):153-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meningioma.
  • Meningiomas are mostly benign tumours originating from the arachnoid cap cells, represent 13-26% of all intracranial tumours.
  • Five-year survival for typical meningiomas exceeds 80%, but is poorer (5-year survival <60%) in malignant and atypical meningiomas.
  • Radiotherapy is currently used in the clinical practice in atypical, malignant or recurrent meningioma at a total dose of 45-60Gy.
  • Radiosurgery has gained more and more importance in the management of meningiomas, especially in meningiomas that cannot be completely resected as for many skull base meningiomas.
  • Medical therapy for patients with recurrent, progressive and symptomatic disease after repeated surgery, radiosurgery and radiotherapy is investigational.
  • [MeSH-major] Meningeal Neoplasms / therapy. Meningioma / therapy
  • [MeSH-minor] Combined Modality Therapy. Humans. Neoplasm Staging. Prognosis. Risk Factors

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  • (PMID = 18342535.001).
  • [ISSN] 1040-8428
  • [Journal-full-title] Critical reviews in oncology/hematology
  • [ISO-abbreviation] Crit. Rev. Oncol. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Number-of-references] 184
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37. Tirakotai W, Mennel HD, Celik I, Hellwig D, Bertalanffy H, Riegel T: Secretory meningioma: immunohistochemical findings and evaluation of mast cell infiltration. Neurosurg Rev; 2006 Jan;29(1):41-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secretory meningioma: immunohistochemical findings and evaluation of mast cell infiltration.
  • Secretory meningiomas constitute a relatively rare subtype of meningiomas, accounting for only 1.1% at our institution, with a 6:1 predominance of female patients.
  • This study aimed to obtain more information about the immunohistochemical characteristics of this histological entity, and to analyse the effects of histological factors such as the presence of mast cells on the radiological evidence of surrounding tumour oedema that frequently occurred in this subtype of meningioma.
  • Fourteen cases of secretory meningioma were examined.
  • In order to perform the quantitative evaluation of mast cells in secretory meningiomas in a comparison with other meningiomas, 14 non-secretory meningiomas were randomly selected and used as a control group.
  • The immunohistochemical staining of carcinoembryonic antigen was positive within the secretory droplets and the cells surrounding them in all cases.
  • Ki 67 (MIB 1) proliferative index mean values were 2.4%, indicating low expression in all secretory meningiomas.
  • Moreover, from our statistical analysis, there is no clear-cut pattern of various types of cytokeratins emerging in secretory meningiomas.
  • The secretory meningiomas were characterized by a significantly increased number of mast cells as compared with non-secretory meningiomas of different grades.
  • [MeSH-major] Mast Cells / chemistry. Mast Cells / pathology. Meningeal Neoplasms / chemistry. Meningeal Neoplasms / immunology. Meningioma / chemistry. Meningioma / immunology
  • [MeSH-minor] Actins / analysis. Adult. Aged. Brain Edema / epidemiology. Brain Edema / pathology. Carcinoembryonic Antigen / analysis. Cell Movement. Cell Proliferation. Female. Humans. Immunohistochemistry. Incidence. Keratins / analysis. Ki-67 Antigen / analysis. Male. Middle Aged. Mucin-1 / analysis. Pericytes / pathology. Vimentin / analysis

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  • (PMID = 16010579.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins; 0 / Carcinoembryonic Antigen; 0 / Ki-67 Antigen; 0 / Mucin-1; 0 / Vimentin; 68238-35-7 / Keratins
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38. Ereño C, Izquierdo AP, Basurko JM, Bilbao FJ, López JI: Temporal bone secretory meningioma presenting as a middle ear mass. Pathol Res Pract; 2006;202(6):481-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Temporal bone secretory meningioma presenting as a middle ear mass.
  • CT scan revealed a tumor occupying the mastoid, middle ear, and external auditory canal.
  • After surgical removal, a typical secretory meningioma was diagnosed.
  • The histological hallmark and the immunohistochemical profile of secretory meningiomas are reviewed.
  • The differential diagnosis of this tumor in this location is also commented on.
  • As far as we know, primary temporal bone meningiomas with secretory histology have not been previously reported in the medical literature.
  • [MeSH-major] Ear Neoplasms / diagnosis. Ear, Middle / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology. Skull Neoplasms / pathology. Temporal Bone / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans

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  • (PMID = 16517091.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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39. Hirunwiwatkul P, Trobe JD, Blaivas M: Lymphoplasmacyte-rich meningioma mimicking idiopathic hypertrophic pachymeningitis. J Neuroophthalmol; 2007 Jun;27(2):91-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoplasmacyte-rich meningioma mimicking idiopathic hypertrophic pachymeningitis.
  • Brain MRI showed meningeal thickening that involved the optic nerves and chiasm and enveloped and displaced the brainstem as far caudally as the foramen magnum.
  • The diffuse extensive nature of the lesion suggested an inflammatory process such as idiopathic hypertrophic pachymeningitis (IHP), but anterior temporal brain biopsy disclosed a relatively high proportion of meningothelial cells with islands of polyclonal inflammatory reaction consistent with a diagnosis of lymphoplasmacyte-rich meningioma (LRM), a rare variant.
  • [MeSH-major] Dura Mater / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Meningitis / diagnosis. Plasma Cells / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Hypertrophy. Magnetic Resonance Imaging. Male

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  • [CommentIn] J Neuroophthalmol. 2007 Jun;27(2):89-90 [17548989.001]
  • (PMID = 17548990.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Llauger J, Aixut S, Cañete N, Palmer J, Solà M, Bagué S: Meningioma of the scapula. Skeletal Radiol; 2008 Feb;37(2):169-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meningioma of the scapula.
  • Meningiomas account for approximately 15% of all intracranial tumors and are the most common non-glial primary tumors of the central nervous system.
  • Most meningiomas are benign neoplasms with characteristic imaging features.
  • Primary extradural meningiomas account for only 1-2% of all meningiomas.
  • They must be differentiated from intradural meningiomas with secondary extradural extension and/or metastases.
  • The vast majority of extradural meningiomas are found in the skull or in the head and neck region.
  • We report on an extremely rare case of primary extradural meningioma that was located in the scapula.
  • To the best of our knowledge, this form of presentation of an extradural meningioma has not been previously described.
  • [MeSH-major] Bone Neoplasms / diagnosis. Meningioma / diagnosis. Scapula / pathology. Scapula / radiography
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Rare Diseases. Shoulder Pain / etiology. Tomography, X-Ray Computed

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  • (PMID = 18030466.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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41. Papacocea T, Roşca T, Bădărău A, Papacocea R, Ciornei C, Ion AD: [Cystic meningioma]. Chirurgia (Bucur); 2009 Jan-Feb;104(1):99-103
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cystic meningioma].
  • [Transliterated title] Meningiom chistic--prezentare de caz.
  • Cystic meningioma represent a rare entity, accounting 1.7 to 11.7% from the total intracranial meningiomas.
  • The anatomo-pathological result: meningothelial meningioma.
  • [MeSH-major] Cysts. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis

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  • (PMID = 19388576.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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42. Matyja E, Naganska E, Zabek M, Jagielski J: Meningioma with the unique coexistence of secretory and lipomatous components: a case report with immunohistochemical and ultrastructural study. Clin Neuropathol; 2005 Nov-Dec;24(6):257-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meningioma with the unique coexistence of secretory and lipomatous components: a case report with immunohistochemical and ultrastructural study.
  • Meningiomas exhibit a broad spectrum of differentiation potency corresponding to different histological subtypes.
  • The separate secretory or lipomatous transformation of meningothelial cells is uncommonly encountered in meningiomas classified into distinct secretory or lipomatous variants.
  • We report an exceptional case of secretory meningioma associated with extensive lipomatous component in a 58-year-old woman.
  • CT scan and MRI of the brain showed a well-defined tumor mass in the right temporal lobe with areas of adipose tissue and extensive surrounding brain edema.
  • Microscopically, the tumor was composed of two components: whorls of meningothelial cells with numerous PAS-positive hyaline inclusions (pseudopsammoma bodies) and numerous mature adipocyte-like cells.
  • The hyaline inclusions and tumor cells surrounding them showed strong immunoreactivity for EMA and CEA.
  • Ultrastructural findings confirmed both secretory and lipomatous differentiation of tumor cells.
  • The present case of meningioma demonstrates a unique coexistence of secretory and lipomatous meningothelial components, reflecting the multipotency of phenotypic transformation of primary meningothelial cells.
  • [MeSH-major] Meningeal Neoplasms / metabolism. Meningeal Neoplasms / pathology. Meningioma / metabolism. Meningioma / pathology

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  • [CommentIn] Clin Neuropathol. 2006 Jul-Aug;25(4):204 [16866303.001]
  • (PMID = 16320819.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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43. Hokazono K, Moura FC, Monteiro ML: [Optic nerve meningioma mimicking progression of glaucomatous axonal damage: a case report]. Arq Bras Oftalmol; 2008 Sep-Oct;71(5):725-8
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  • [Title] [Optic nerve meningioma mimicking progression of glaucomatous axonal damage: a case report].
  • [Transliterated title] Meningioma do nervo óptico simulando progressão de dano axonal glaucomatoso: relato de caso.
  • To report a case of an optic nerve sheath meningioma located at the optic canal area mimicking the progression of a glaucomatous axonal damage.
  • A computerized tomography scan of the orbit was normal but a high-resolution magnetic resonance imaging demonstrated an optic nerve sheath meningioma located at the optic canal area.
  • [MeSH-major] Glaucoma / diagnosis. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Optic Nerve Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 19039473.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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44. Alonso Seco A, Polo López R, Labatut Pesce T, Fogué Calvo L: [Meningioma of the internal auditory canal: A rare entity]. Acta Otorrinolaringol Esp; 2010 Sep-Oct;61(5):387-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Meningioma of the internal auditory canal: A rare entity].
  • [Transliterated title] Meningioma del conducto auditivo interno: una rara entidad.
  • The final histopathological analysis revealed it to be a meningioma.
  • [MeSH-major] Ear Neoplasms. Ear, Inner. Meningioma

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  • [Copyright] Copyright © 2009 Elsevier España, S.L. All rights reserved.
  • (PMID = 19914594.001).
  • [ISSN] 1988-3013
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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45. Braham E, Bellil S, Ben Hamouda K, Bettaieb I, Mekni A, Bellil K, Haouet S, Zitouna M, Kchir N: [Chordoid meningioma. Two cases]. Neurochirurgie; 2007 Feb;53(1):39-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Chordoid meningioma. Two cases].
  • Chordoid meningioma is an uncommon histopathological variant of meningioma frequently confused with chordoma.
  • We report two cases of chordoid meningioma occurring in two women aged 47 and 63 years.
  • Both women presented neurological signs without systemic disease.
  • Histopathologic findings were consistent with chordoid meningioma.
  • [MeSH-major] Chordoma / surgery. Meningeal Neoplasms / surgery. Meningioma / surgery
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Epilepsy, Tonic-Clonic / etiology. Female. Humans. Magnetic Resonance Imaging. Meninges / pathology. Meninges / surgery. Middle Aged. Mucin-1 / analysis. Neurologic Examination. Tomography, X-Ray Computed. Vimentin / analysis

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  • (PMID = 17337015.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Mucin-1; 0 / Vimentin
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46. Singh SK, Ojha BK, Chandra A, Rastogi M, Husain M, Husain N: Scalp meningioma. Indian J Dermatol; 2008;53(4):196-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scalp meningioma.
  • Primary extracranial meningiomas occur very rarely.
  • We present a rare case of extracranial meningioma of the transitional variant which was excised satisfactorily.
  • There was no suggestion of any connection to the intracranial compartment or cranial nerves.
  • This rare diagnosis should nonetheless be kept in the differential diagnosis of scalp tumors.

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  • [Cites] Cytopathology. 1999 Feb;10(1):54-60 [10068888.001]
  • [Cites] J Dermatol. 1995 Aug;22(8):611-9 [7560462.001]
  • [Cites] J Cutan Pathol. 1989 Apr;16(2):72-80 [2474587.001]
  • [Cites] Neuroradiology. 1974;6(5):246-53 [4810615.001]
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  • [Cites] Neurol India. 2000 Mar;48(1):94-5 [10751830.001]
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  • [Cites] Cancer. 1974 Sep;34(3):728-44 [4851231.001]
  • (PMID = 19882035.001).
  • [ISSN] 1998-3611
  • [Journal-full-title] Indian journal of dermatology
  • [ISO-abbreviation] Indian J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2763757
  • [Keywords] NOTNLM ; Ectopic / meningioma / scalp / transitional
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47. Agrawal V, Ludwig N, Agrawal A, Bulsara KR: Intraosseous intracranial meningioma. AJNR Am J Neuroradiol; 2007 Feb;28(2):314-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraosseous intracranial meningioma.
  • Primary intraosseous lytic meningiomas are rare tumors, with only 16 cases described in the literature.
  • We present a case in which CT and MR imaging with contrast agent helped diagnose preoperatively an enlarging skull mass as a primary intraosseous lytic meningioma in a 70-year-old woman.
  • [MeSH-major] Meningioma / pathology. Meningioma / radiography. Skull Neoplasms / pathology. Skull Neoplasms / radiography

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  • (PMID = 17297003.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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48. Cuccurullo L, Parlato C, Luongo M, Accardo M: Ultrastructural profile of microcystic meningioma. Pathologica; 2009 Jun;101(3):115-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrastructural profile of microcystic meningioma.
  • OBJECTIVE: Microcystic meningioma was originally classified as a subtype of meningioma by the World Health Organization classification of brain tumours in 1993, and accounts for 1.6% of intracranial meningiomas.
  • This subtype is a variety of meningioma in which micro- and macro-cysts are diffuse.
  • The morphologic characteristics are well defined, while the histogenetic mechanism that give rise to these patterns remain unclear.
  • MATERIALS AND METHODS: The authors present an electron microscopic study of an unusual case of fronto-temporal microcystic meningioma, manifesting as history of headache, right paresis and dysphasia in a 73-year-old female.
  • [MeSH-major] Meningeal Neoplasms / ultrastructure. Meningioma / ultrastructure

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  • (PMID = 19886545.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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49. Magliulo G, Alla FR, Colicchio G, Trasimeni G: Geniculate ganglion meningioma. Skull Base; 2010 May;20(3):185-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Geniculate ganglion meningioma.
  • The geniculate ganglion is an unusual location for an intratemporal/intracranial meningioma.
  • We present a case of meningioma intrinsic to the geniculate ganglion that presented peculiar features on high-resolution computed tomography (HRCT) and magnetic resonance imaging.
  • Although intracranial meningiomas can have calcifications within the mass, none of the cases of geniculate ganglion meningiomas described in the literature presented with calcifications.
  • The presence of calcifications led us to suspect a meningioma of the geniculate segment, which was confirmed at histological examination.

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  • [Cites] AJNR Am J Neuroradiol. 2003 Sep;24(8):1642-5 [13679286.001]
  • [Cites] Skull Base. 2001 Nov;11(4):297-302 [17167632.001]
  • [Cites] AJNR Am J Neuroradiol. 1995 May;16(5):1144-6 [7639141.001]
  • [Cites] Am J Otol. 1997 May;18(3):393-7 [9149837.001]
  • [Cites] Pediatr Radiol. 1997 Nov;27(11):847-9 [9361041.001]
  • (PMID = 21318036.001).
  • [ISSN] 1532-0065
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3037106
  • [Keywords] NOTNLM ; Geniculate ganglion / facial graft / meningioma / skull base surgery
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50. Llorente-González S, Arbizu-Duralde A, Pastora-Salvador N: [Fractionated stereotactic radiotherapy in optic nerve sheath meningioma]. Arch Soc Esp Oftalmol; 2008 Jul;83(7):441-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Fractionated stereotactic radiotherapy in optic nerve sheath meningioma].
  • [Transliterated title] Radioterapia fraccionada estereotáctica en el meningioma del nervio óptico.
  • CASE REPORT: A 56-year-old woman with a right optic nerve sheath meningioma and visual loss, was treated with fractionated stereotactic radiotherapy.
  • DISCUSSION: Currently there are many different alternatives available for the management of an optic nerve sheath meningioma: observation, surgery, conventional radiotherapy and fractionated stereotactic radiotherapy.
  • The last of these treatments has been demonstrated to preserve or improve vision in 2 out of 3 treated patients, with fewer side effects, and has not been associated with recurrent disease or tumor progression.
  • [MeSH-major] Meningioma / surgery. Optic Nerve Neoplasms / surgery. Radiosurgery

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  • (PMID = 18592446.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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51. Khong SY, Leach J, Greenwood C: Meningioma mimicking puerperal psychosis. Obstet Gynecol; 2007 Feb;109(2 Pt2):515-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meningioma mimicking puerperal psychosis.
  • BACKGROUND: Meningiomas are slow-growing benign brain tumors.
  • Meningioma was diagnosed by computed tomography and treated successfully with steroids, anticonvulsant, and craniotomy.
  • Neuroimaging should be performed in the presence of any neurologic abnormality to exclude intracranial lesions such as meningioma.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Psychotic Disorders / etiology. Puerperal Disorders / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Pregnancy. Pregnancy Trimester, Third

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  • (PMID = 17267878.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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52. Friis M, Klokker M, Fugleholm K: [Ménière's-like symptoms following meningioma]. Ugeskr Laeger; 2010 Apr 12;172(15):1136-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ménière's-like symptoms following meningioma].
  • [Transliterated title] Menière-lignende symptomer efter meningeom.
  • A 36-year-old woman who presented with a right sided hearing loss, tinnitus and attacks of dizziness was initially diagnosed with Ménière's disease.
  • A meningioma was found along the posterior surface of the petrosal bone, centred partly on the external aperture of the vestibular aqueduct with no relation to the meatal canal.
  • [MeSH-major] Meniere Disease / etiology. Meningeal Neoplasms / complications. Meningioma / complications
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging

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  • (PMID = 20427006.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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53. Cotrina Monroy AP, López López A, Ruiz Solis S, Gómez Embuena A: [Incidental finding of a meningioma-en-plaque in a patient with prostate adenocarcinoma]. Rev Esp Med Nucl; 2010 Sep-Oct;29(5):254-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Incidental finding of a meningioma-en-plaque in a patient with prostate adenocarcinoma].
  • [Transliterated title] Hallazgo incidental de un meningioma en placa en un paciente con adenocarcinoma de próstata.
  • Meningiomas-en-plaques (MEP) are characterized by an area of hyperostosis and constitute a diagnostic challenge, especially when associated with other underlying conditions, and may mimic other clinical conditions.
  • We present a case of a large MEP, which was an incidental finding on a scintigraphy study of a patient with prostate adenocarcinoma, this finding being histologically confirmed.
  • [MeSH-major] Adenocarcinoma / radionuclide imaging. Incidental Findings. Meningeal Neoplasms / radionuclide imaging. Meningioma / radionuclide imaging. Neoplasms, Multiple Primary / radionuclide imaging. Prostatic Neoplasms / radionuclide imaging
  • [MeSH-minor] Aged. Craniocerebral Trauma / radionuclide imaging. Diagnosis, Differential. Diagnostic Errors. Exophthalmos / etiology. Headache / etiology. Humans. Magnetic Resonance Imaging. Male. Osteitis Deformans / radionuclide imaging. Radiopharmaceuticals. Skull Neoplasms / radionuclide imaging. Skull Neoplasms / secondary. Technetium Tc 99m Medronate. Tomography, X-Ray Computed

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  • [Copyright] Copyright © 2009 Elsevier España, S.L. y SEMNIM. All rights reserved.
  • (PMID = 20398966.001).
  • [ISSN] 0212-6982
  • [Journal-full-title] Revista española de medicina nuclear
  • [ISO-abbreviation] Rev Esp Med Nucl
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; X89XV46R07 / Technetium Tc 99m Medronate
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54. Claus EB, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M, Black PM: Epidemiology of intracranial meningioma. Neurosurgery; 2005 Dec;57(6):1088-95; discussion 1088-95
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiology of intracranial meningioma.
  • Meningiomas are the most frequently reported primary intracranial neoplasms, accounting for approximately 25% of all such lesions diagnosed in the United States.
  • Few studies have examined the risk factors associated with a diagnosis of meningioma with two categories of exposure, hormones (both endogenous and exogenous) and radiation, most strongly associated with meningioma risk.
  • Limited data are also available on long-term outcomes for meningioma patients, although it is clear that the disease is associated with significant morbidity and mortality.
  • Recent legislation passed in the United States (The Benign Brain Tumor Cancer Registries Amendment Act [H.R.
  • 5204]) mandates registration of benign brain tumors such as meningioma.
  • This will increase the focus on this disease over the coming years as well as likely increase the reported prevalence of the disease.
  • The increased emphasis on research dedicated to the study of brain tumors coupled with the advent of new tools in genetic and molecular epidemiology make the current era an ideal time to advance knowledge for intracranial meningioma.
  • This review highlights current knowledge of meningioma epidemiology and new directions for research efforts in this field.

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  • (PMID = 16331155.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R25 CA089017; United States / NCI NIH HHS / CA / 5R25-CA089017-03; United States / NCI NIH HHS / CA / P50-CA097257; United States / NCI NIH HHS / CA / R01-CA52689
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 76
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55. Kalamarides M, Peyre M, Giovannini M: Meningioma mouse models. J Neurooncol; 2010 Sep;99(3):325-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meningioma mouse models.
  • Meningiomas, although mostly benign, may sometimes present aggressive features and raise issues concerning alternative treatment options besides surgery.
  • In order to gain new insights in meningioma biology and develop alternative treatments, several meningioma mouse models have been engineered during the past two decades.
  • As rodents very rarely develop spontaneous meningiomas, animal models have been first developed by implanting human meningioma cells derived from a primary tumor and meningioma cell lines subcutaneously into athymic mice.
  • Induction of de novo meningiomas in rodents with mutagens, such as nitrosourea, has also been reported.
  • Advances in our understanding of molecular genetics of meningioma have pinpointed the central role of NF2 tumor suppressor gene in the pathogenesis of those tumors.
  • These discoveries have led to the creation of a genetically engineered model utilizing conditional mutagenesis to specifically inactivate the mouse Nf2 gene in arachnoidal cells, resulting in the formation of intracranial meningothelial hyperplasia and meningiomas and thus reproducing the main mechanism of human meningeal tumorigenesis.
  • This powerful new technology significantly improves on prior models and may open avenues of investigation never before possible in meningioma research.
  • We present here a review of current meningioma mouse models used in translational therapeutics with associated imaging and pre-clinical studies.
  • [MeSH-major] Disease Models, Animal. Meningeal Neoplasms / pathology. Meningioma / pathology

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  • (PMID = 20734219.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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56. Thakorlal A, Wong DC, Anderson RJ: Incidental finding of meningioma on bone scintigraphy. Australas Radiol; 2005 Jun;49(3):238-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidental finding of meningioma on bone scintigraphy.
  • An incidental finding of an intracranial posterior fossa meningioma detected by bone scintigraphy is presented.
  • Most of the published literature on the diagnosis of meningioma is on the use of CT and MRI.
  • There is limited published literature on the detection of meningioma with bone scintigraphy.
  • [MeSH-major] Bone and Bones / radionuclide imaging. Meningeal Neoplasms / radionuclide imaging. Meningioma / radionuclide imaging

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  • (PMID = 15932468.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; X89XV46R07 / Technetium Tc 99m Medronate
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57. Norden AD, Drappatz J, Wen PY: Advances in meningioma therapy. Curr Neurol Neurosci Rep; 2009 May;9(3):231-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Advances in meningioma therapy.
  • Meningiomas are the most common primary brain tumors in adults.
  • Surgical resection is curative when complete removal of a benign meningioma is possible.
  • Incompletely resected tumors and high-grade lesions are frequently treated with fractionated radiotherapy or stereotactic radiosurgery.
  • High-grade meningiomas tend to recur following maximal treatment with surgery and radiation.
  • Chemotherapeutic agents, including hydroxyurea, have been used for recurrent disease with marginal efficacy.
  • As the molecular pathogenesis of meningiomas is elucidated, targeted drug therapies may prove useful.
  • [MeSH-major] Meningeal Neoplasms / therapy. Meningioma / therapy

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  • (PMID = 19348712.001).
  • [ISSN] 1534-6293
  • [Journal-full-title] Current neurology and neuroscience reports
  • [ISO-abbreviation] Curr Neurol Neurosci Rep
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 81
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58. van der Meij JJ, Boomars KA, van den Bosch JM, van Boven WJ, de Bruin PC, Seldenrijk CA: Primary pulmonary malignant meningioma. Ann Thorac Surg; 2005 Oct;80(4):1523-5
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  • [Title] Primary pulmonary malignant meningioma.
  • Primary pulmonary meningiomas are relatively rare and mostly benign.
  • To exclude pulmonary metastasis of an intracranial meningioma, imaging studies of the brain should be performed.
  • We believe that only one primary pulmonary malignant meningioma in which a metastasis from the brain was excluded has been reported.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Bronchial Neoplasms / pathology. Meningioma / diagnosis. Meningioma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Esophageal Neoplasms / pathology. Female. Humans. Liver Neoplasms / secondary. Magnetic Resonance Imaging. Meningeal Neoplasms / diagnosis. Neoplasm Invasiveness. Pleural Neoplasms / pathology. Treatment Outcome

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  • (PMID = 16181912.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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59. Moradi A, Semnani V, Djam H, Tajodini A, Zali AR, Ghaemi K, Nikzad N, Madani-Civi M: Pathodiagnostic parameters for meningioma grading. J Clin Neurosci; 2008 Dec;15(12):1370-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathodiagnostic parameters for meningioma grading.
  • Meningiomas are usually slow-growing benign tumors, for which complete removal can be difficult and recurrence is an issue.
  • In this study the relationship between pathodiagnostic parameters, histological grade, and MIB-1 monoclonal antibody expression in meningioma diagnosed over 10 years in Shohada Hospital, Tehran, was assessed.
  • Between January 1997 and December 2006, a total of 4885 intracranial tumors were diagnosed at Shohada Hospital, 378 (7.74%) of which were meningiomas.
  • The mean age of patients with meningiomas was 49.11+/-12.99 years (range 6-78 years, median=50); females outnumbered males by a ratio of 1.7 to 1.
  • Convexity meningiomas were most common, followed by meningiomas of the sphenoid ridge and cerebellopontine angle.
  • There was no relationship between the location of the tumor and the histopathological features.
  • Histopathological study of completely resected meningiomas showed that loss of architecture, frequent mitotic figures, a high cellularity, increased nucleo-cytoplasmic ratio, a prominent nucleolus, brain invasion, and necrosis were correlated with the grade of the meningiomas.
  • Overall, the mitotic count was the most important marker for tumor grade.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningioma / diagnosis

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  • (PMID = 18819804.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] EC 6.3.2.19 / MIB1 ligase, human; EC 6.3.2.19 / Ubiquitin-Protein Ligases
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60. Nicula C, Călugăru M, Roşca G, Blidaru M: [Choroidal melanoma associated with intracerebral meningioma]. Oftalmologia; 2006;50(3):52-7
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  • [Title] [Choroidal melanoma associated with intracerebral meningioma].
  • [Transliterated title] Melanom malign coroidian asociat cu meningiom intracerebral - caz clinic-.
  • The authors present the case of a female patient with intraocular malignant melanoma associated with intracerebral meningioma, diagnosed by the preoperative evaluation.
  • [MeSH-major] Choroid Neoplasms. Melanoma. Meningeal Neoplasms. Meningioma. Neoplasms, Multiple Primary

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  • (PMID = 17144507.001).
  • [ISSN] 1220-0875
  • [Journal-full-title] Oftalmologia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Oftalmologia
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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61. Dutta D, Lee HN, Munshi A, Gupta T, Kane S, Sridhar E, Jalali R: Intracerebral cystic rhabdoid meningioma. J Clin Neurosci; 2009 Aug;16(8):1073-4
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  • [Title] Intracerebral cystic rhabdoid meningioma.
  • An MRI of the brain revealed a left temporal intracerebral cystic lesion with rim enhancement.
  • The patient was diagnosed as having an intracerebral cystic rhabdoid meningioma.
  • Cystic intracerebral rhabdoid meningiomas are rare.
  • We discuss the clinical picture of this patient with reference to the published literature on this uncommon diagnosis.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / therapy. Meningioma / diagnosis. Meningioma / therapy. Rhabdoid Tumor / diagnosis. Rhabdoid Tumor / therapy
  • [MeSH-minor] Adult. Brain / pathology. Brain / radiation effects. Brain / surgery. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging

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  • (PMID = 19427788.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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62. Yang X, Gao X, Wang S: Primary mediastinal malignant meningioma. Eur J Cardiothorac Surg; 2009 Jul;36(1):217-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mediastinal malignant meningioma.
  • Primary ectopic meningiomas are extremely rare tumors of controversial origin and they are usually limited to the head and neck region.
  • There has not been any official report regarding primary mediastinal malignant meningioma until today.
  • Because of its rarity and potential value, we report here a case of primary mediastinal malignant meningioma, which turns out to be the first reported case of this type of meningioma.
  • The clinical features, treatment plans, pathological findings, as well as prognosis of a case of primary mediastinal malignant meningioma were carefully analyzed and the literature on ectopic meningioma was reviewed.
  • The diagnosis of ectopic meningioma can only be established based on microscopic and immunohistochemical findings.
  • Surgery is the treatment of choice for ectopic meningioma and postoperative radiotherapy should be managed for patients with suspected invasive meningioma.
  • [MeSH-major] Mediastinal Neoplasms / radiography. Meningioma / radiography

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  • (PMID = 19410481.001).
  • [ISSN] 1873-734X
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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63. Zhao JQ, Liang BL, Shen J, Tan XP, Zhang XH: [Proton spectroscopy findings of meningioma]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2005 Mar;36(2):253-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Proton spectroscopy findings of meningioma].
  • OBJECTIVE: To evaluate the characteristics of 1HMRSI and its diagnostic value on meningioma.
  • METHODS: The findings of conventional MRI and of 1HMRSI from 11 cases of clinically proven meningiomas and from 12 normal volunteers were comparatively analyzed.
  • The imaging sequences included T1-weighted imaging and T2-weighted imaging; additionally T1-weighted imaging with injection of the contrast agent of Gd-DTPA was performed in all meningioma cases.
  • RESULTS: On conventional pre-contrast MRI, the signals in 8 meningioma cases showed medium or faintly low intensities and in 3 cases showed mixed intensities on T1WI.
  • After injection of Gd-DTPA, the solid portion of tumors exhibited obvious enhancement in all meningioma cases.
  • "Dural trail sign" was revealed in 7 cases.
  • Peri-tumor edema was evident in 11 meningioma cases.
  • Compared with control group, 1HMRSI of all meningiomas revealed different spectral peaks, including absent acetylaspartate (NAA), prominent choline (Cho), and reduced phosphocreatine (Pcr).
  • The peak of lactate (Lac) was visualized in 2 meningioma cases.
  • CONCLUSION: Most cases of meningioma can be diagnosed with conventional magnetic resonance imaging (MRI).
  • 1HMRSI can yield more informative findings about meningioma via the observed metabolic materials changes in tumor cells.
  • So conventional MRI is the most important technology for diagnosing meningioma and 1HMRS combined with MRI can improve the diagnostic accuracy.
  • 1HMRSI can be an important supplemental means in the diagnosis of meningiomas.
  • [MeSH-major] Magnetic Resonance Spectroscopy. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis

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  • (PMID = 15807281.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Protons
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64. Henon A, Colombat M, Rodallec M, Redondo A, Feydy A: [Intraosseous meningioma of the skull: radiologic pathologic correlation]. J Radiol; 2005 Jan;86(1):83-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intraosseous meningioma of the skull: radiologic pathologic correlation].
  • Intraosseous meningiomas are rare ectopic meningiomas.
  • The authors report the case of a hyperostotic intraosseous meningioma of the parietal bone without dural extension.
  • [MeSH-major] Meningioma / pathology. Meningioma / radiography. Skull Neoplasms / pathology. Skull Neoplasms / radiography

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  • (PMID = 15785422.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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65. Palimento D, Picchio M: Meningioma of the mediastinum causing spontaneous hemothorax. Ann Thorac Surg; 2006 May;81(5):1903-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meningioma of the mediastinum causing spontaneous hemothorax.
  • Ectopic meningiomas are extremely rare.
  • Mediastinal tumors may rarely cause spontaneous hemothorax.
  • We report a case of angioblastic meningioma of the posterior mediastinum causing spontaneous hemothorax.
  • [MeSH-major] Hemothorax / etiology. Mediastinum. Meningioma / complications. Thoracic Neoplasms / complications

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  • (PMID = 16631706.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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66. Goldsmith B, McDermott MW: Meningioma. Neurosurg Clin N Am; 2006 Apr;17(2):111-20, vi
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meningioma.
  • Total excision is an appropriate treatment option for patients with benign meningiomas that are resectable with minimal morbidity.
  • Fractionated conformal radiotherapy is an appropriate primary treatment option for patients with benign meningiomas of all sizes and all sites.
  • It is particularly appropriate and preferred for optic nerve sheath meningiomas, for which there are few alternatives.
  • After subtotal resection, it is appropriate to offer single-fraction radiosurgery or multifraction radiotherapy, depending on the size, location, and extent of residual tumor, so as to achieve progression-free survival and cause-specific survival rates comparable to those of other approaches.
  • [MeSH-major] Meningeal Neoplasms. Meningioma
  • [MeSH-minor] Dose Fractionation. Humans. Magnetic Resonance Imaging. Neoplasm Staging. Neurosurgical Procedures / methods. Radiosurgery / instrumentation. Survival Rate

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  • (PMID = 16793503.001).
  • [ISSN] 1042-3680
  • [Journal-full-title] Neurosurgery clinics of North America
  • [ISO-abbreviation] Neurosurg. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 56
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67. Shelekhova KV: [Extracranial meningioma: morphological and histogenetical aspects and relations with perineurioma]. Arkh Patol; 2010 May-Jun;72(3):12-6
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  • [Title] [Extracranial meningioma: morphological and histogenetical aspects and relations with perineurioma].
  • The clinicomorphological, immunohistochemical, and ultrastructural characteristics of 11 cases of extracranial meningioma versus 79 soft tissue perineuriomas were studied.
  • Considering the point of view that arachnoid and perineurial cells are anatomically, embryologically, and functionally related, it is most possible that extracranial meningiomas may be derived from perineurial cells (or their progenitor cell) rather than from displaced arachnoid cells.
  • [MeSH-major] Ear Neoplasms / pathology. Meningioma / pathology. Nerve Sheath Neoplasms / pathology. Nose Neoplasms / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 20734826.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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68. Karikari IO, Syed NA, Cummings TJ: Secretory meningiomas of the orbit. Orbit; 2009;28(6):408-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secretory meningiomas of the orbit.
  • Meningiomas are histologically heterogeneous tumors with at least 15 different subtypes.
  • The secretory meningioma is a well-differentiated variant, is relatively rare.
  • Orbital involvement of secretory meningiomas is rarity.
  • We report two cases of secretory meningiomas of orbit and review of current literature.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Female. Humans. Immunoenzyme Techniques. Magnetic Resonance Imaging. Middle Aged. Tomography, X-Ray Computed. Visual Acuity

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  • (PMID = 19929671.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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69. Manzano-Palomo MS, Egido JA: [Pontine stroke secondary to a foramen magnum meningioma]. Rev Neurol; 2005 Jun 1-15;40(11):668-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pontine stroke secondary to a foramen magnum meningioma].
  • [Transliterated title] Ictus pontino secundario a meningioma de foramen magno.
  • INTRODUCTION: Meningioma is one of the most frequent tumours affecting the central nervous system, with an estimated incidence of between 15 and 20% of all brain tumours.
  • A computerised tomography scan of the brain revealed a lacunar infarct in said location, with no other appreciable damage.
  • Magnetic resonance imaging of the head revealed a foramen magnum meningioma, with vertebrobasilar vascular distortion.
  • CONCLUSIONS: The case reported here is unique, since it describes a meningioma of the posterior fossa that appears in the form of the initial symptoms of a pontine stroke due to a vascular disorder.
  • [MeSH-major] Cerebral Infarction / etiology. Foramen Magnum. Meningeal Neoplasms / complications. Meningioma / complications. Pons / blood supply

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  • (PMID = 15948070.001).
  • [ISSN] 0210-0010
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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70. Ong L, Ferrucci S: Tuberculum sellae meningioma associated with lymphomatoid papulosis. Optometry; 2005 Mar;76(3):165-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tuberculum sellae meningioma associated with lymphomatoid papulosis.
  • BACKGROUND: Meningiomas involving the tuberculum sellae and planum sphenoidale typically cause visual loss by affecting the optic nerve and anterior chiasm.
  • We present a case of a tuberculum sellae meningioma concurrent with lymphomatoid papulosis, a T-cell lymphomatoid skin disorder.
  • MRI revealed a meningioma arising from the tuberculum sellae and planum sphenoidale region.
  • The meningioma was partially resected nine days later Visual field performed 18 days postoperatively demonstrated an overall depression in the right eye and no defect in the left eye.
  • CONCLUSION: Meningiomas are generally benign tumors that can cause symptoms if vital structures are compromised.
  • Altered visual function and optic atrophy may be the only presentation of intracranial and orbital tumors.
  • Intracranial meningiomas may be associated with systemic conditions that can infiltrate the optic nerve, including lymphocytic disorders.
  • Lymphomatoid papulosis (LyP) is a rare cutaneous disorder involving infiltrating clonal T-cells that has been associated with disseminated lymphomatic skin tumors.
  • It is unclear if there is a direct association between LyP and meningiomas.
  • [MeSH-major] Lymphomatoid Papulosis / complications. Meningeal Neoplasms / complications. Meningioma / complications. Optic Atrophy / etiology. Sella Turcica / pathology. Vision Disorders / etiology

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  • (PMID = 15786635.001).
  • [ISSN] 1529-1839
  • [Journal-full-title] Optometry (St. Louis, Mo.)
  • [ISO-abbreviation] Optometry
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Commins DL, Atkinson RD, Burnett ME: Review of meningioma histopathology. Neurosurg Focus; 2007;23(4):E3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Review of meningioma histopathology.
  • The histological appearance of a meningioma is an important predictor of tumor behavior and is frequently a factor in decisions concerning therapy.
  • Although the latest edition is an improvement over previous grading schemes, the WHO scheme still fails to fully address a variety of important issues regarding the relationship between meningioma histological characteristics and behavior.
  • In particular, routine histological examination fails to identify the subset of Grade I tumors that behave aggressively.
  • It is hoped that an understanding of the genetic changes that underlie tumor progression will improve healthcare professionals' ability to predict the behavior of meningiomas.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Anaplasia / pathology. Antibodies, Antinuclear / metabolism. Antibodies, Monoclonal / metabolism. Humans. Neoplasm Invasiveness

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  • (PMID = 17961040.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / MIB-1 antibody
  • [Number-of-references] 48
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72. Petrulionis M, Valeviciene N, Paulauskiene I, Bruzaite J: Primary extracranial meningioma of the sinonasal tract. Acta Radiol; 2005 Jul;46(4):415-8
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  • [Title] Primary extracranial meningioma of the sinonasal tract.
  • Meningiomas occurring outside the cerebrospinal axis can be primary at an extracranial site (nasal cavity, paranasal sinuses, and nasopharynx) or secondary extending from an intracranial lesion.
  • Magnetic resonance imaging findings of an 8-year-old child with primary meningioma before and after surgery have been reviewed and compared to computed tomography and histological evaluation.
  • After physical and radiological examination, a tumor comprising the left lower, middle turbinate, and ethmoidal cells was found and radically extirpated.
  • On histological examination, the tumor was identified as meningothelial meningioma.
  • On the basis of the clinical, radiological, and histological features, the tumor was diagnosed as extracranial meningioma of the sinonasal tract.
  • A follow-up examination 6 months later revealed no evidence of recurrence of the tumor.
  • [MeSH-major] Meningioma / diagnosis. Paranasal Sinus Neoplasms / diagnosis. Paranasal Sinuses / pathology. Paranasal Sinuses / radiography

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  • (PMID = 16134320.001).
  • [ISSN] 0284-1851
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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73. Genol I, Troyano J, Ariño M, Iglesias I, Arriola P, García-Sánchez J: [Meningocele, glioma and optic nerve meningioma: differential diagnosis and treatment]. Arch Soc Esp Oftalmol; 2009 Nov;84(11):563-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Meningocele, glioma and optic nerve meningioma: differential diagnosis and treatment].
  • [Transliterated title] Meningocele, glioma y meningioma del nervio óptico: diagnóstico diferencial y tratamiento.
  • PURPOSE: After studying 3 clinical cases, we have reviewed the clinical and radiological characteristics of meningocele, meningioma and optic nerve glioma.
  • The differential diagnosis and therapeutic management are also discussed.
  • METHODS: Review of three clinical reports of three patients seen in our unit and a bibliographic search concerning the diagnosis and therapeutic management of these three entities at the present time.
  • RESULTS: Differential diagnosis has to be based on a wide range of parameters: epidemiologic (age, race, sex, prevalence of the tumors), clinical (visual acuity, perimetry, Hertel exophthalmometry and funduscopy) and radiologic (computed tomography and magnetic resonance).
  • CONCLUSION: A correct differential diagnosis is mandatory to be able to individualize the treatment for each entity (Arch Soc Esp Oftalmol 2009; 84: 563-568).
  • [MeSH-major] Meningioma / diagnosis. Meningioma / therapy. Meningocele / diagnosis. Meningocele / therapy. Optic Nerve Neoplasms / diagnosis. Optic Nerve Neoplasms / therapy
  • [MeSH-minor] Adult. Child, Preschool. Diagnosis, Differential. Female. Humans. Male. Optic Nerve Glioma / diagnosis. Optic Nerve Glioma / therapy

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  • (PMID = 19967609.001).
  • [ISSN] 1989-7286
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 21
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74. Schmidt JH, Soll NH, Svane-Knudsen V: [Meningioma as the cause of ear problems]. Ugeskr Laeger; 2010 Feb 8;172(6):462-3
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  • [Title] [Meningioma as the cause of ear problems].
  • [Transliterated title] Meningiom som årsag til øregener.
  • A 45-year-old woman with long-term unilateral ear problems, hearing loss, vertigo and tinnitus was diagnosed with a meningioma in the middle ear.
  • Magnetic resonance imagining (MRI) revealed that the meningioma penetrated the petrous bone into the middle ear.
  • The meningioma was removed to avoid further hearing loss.
  • [MeSH-major] Ear Diseases / etiology. Meningeal Neoplasms / complications. Meningioma / complications

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  • (PMID = 20146913.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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75. Chamberlain MC, Glantz MJ: Cerebrospinal fluid-disseminated meningioma. Cancer; 2005 Apr 1;103(7):1427-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebrospinal fluid-disseminated meningioma.
  • BACKGROUND: Intracranial meningiomas are common and comprise 20% of all primary brain tumors.
  • Meningiomas infrequently metastasize; however, to the authors' knowledge there are limited data regarding the spread of disease through cerebrospinal fluid (CSF).
  • METHODS: Eight of 200 consecutive patients (4%) with meningiomas manifested CSF dissemination.
  • Multiple sites of metastases were seen in all patients and were both within the nervous system (subarachnoid or ventricular tumor: intracranial in eight patients, spinal cord in four patients) and extraneural (subcutaneous, cervical lymph nodes, orbit, or pulmonary in five patients).
  • The best response was stable disease in seven patients and progressive disease in one patient.
  • The median survival was 5.5 months, and 3 patients were alive with disease at the time of last follow-up.
  • CONCLUSIONS: The treatment of CSF-disseminated meningioma, although feasible and comparatively nontoxic, was associated with modest outcomes despite combined systemic and intraventricular chemotherapy.
  • [MeSH-major] Meningioma / secondary
  • [MeSH-minor] Adult. Aged. Antineoplastic Agents / therapeutic use. Brain Neoplasms / pathology. Brain Neoplasms / secondary. Central Nervous System Neoplasms / secondary. Cerebrospinal Fluid / cytology. Female. Humans. Lung Neoplasms / secondary. Lymphatic Metastasis. Male. Middle Aged. Skin Neoplasms / secondary. Spinal Cord Neoplasms / secondary

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  • [Copyright] Copyright 2005 American Cancer Society.
  • (PMID = 15690330.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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76. Ohba S, Yoshida K, Akiyama T, Ikeda E, Kawase T: Lipomatous meningioma. J Clin Neurosci; 2007 Oct;14(10):1003-6
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  • [Title] Lipomatous meningioma.
  • We present a case of intracranial lipomatous meningioma in the parietal convexity in a 64-year-old woman.
  • Gross total removal of the tumor was performed.
  • Histopathologically, the tumor was a meningioma with mixed transitional and lipomatous patterns.
  • We review previous reports of lipomatous meningioma and discuss its clinical presentations and pathology.
  • [MeSH-major] Lipoma / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Ki-67 Antigen / metabolism. Magnetic Resonance Imaging. Middle Aged. Mucin-1 / analysis. Mucin-1 / metabolism. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / physiopathology. Neurosurgical Procedures. Parietal Lobe / pathology. Parietal Lobe / physiopathology. Tomography, X-Ray Computed. Vimentin / analysis. Vimentin / metabolism

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  • (PMID = 17240148.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Mucin-1; 0 / Vimentin
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77. Etienne-Mastroianni B, Girard N, Ginguene C, Tronc F, Vasiljevic A, Vallee B, Cordier JF: [Pulmonary metastases from malignant meningioma]. Rev Mal Respir; 2010 Sep;27(7):764-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pulmonary metastases from malignant meningioma].
  • INTRODUCTION: Pulmonary metastases from meningioma are rare and present with specific clinical and radiological features.
  • The diagnostic and therapeutic management of metastatic meningioma illustrate the concept of orphan thoracic oncology.
  • CASE REPORT: We report the case of a 58-year-old male, former smoker, with a previous history of atypical meningioma and resected lung adenocarcinoma.
  • Pathological examination of metastasectomy specimens revealed metastatic malignant meningioma.
  • CONCLUSIONS: Pulmonary metastases may occur in malignant meningioma.
  • [MeSH-major] Lung Neoplasms / secondary. Meningeal Neoplasms / pathology. Meningioma / secondary

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  • [Copyright] Copyright © 2010 SPLF. Published by Elsevier Masson SAS. All rights reserved.
  • (PMID = 20863979.001).
  • [ISSN] 1776-2588
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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78. Rowsell C, Sirbovan J, Rosenblum MK, Perez-Ordoñez B: Primary chordoid meningioma of lung. Virchows Arch; 2005 Mar;446(3):333-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary chordoid meningioma of lung.
  • Primary meningiomas of the lung are rare.
  • Most pulmonary meningiomas are typical syncytial or transitional meningiomas with smaller numbers of fibrous-type tumors.
  • Herein, we report an unusual pulmonary tumor with the microscopic, immunohistochemical, and ultrastructural characteristics of a chordoid meningioma.
  • The tumor was composed of cords and fascicles of small- to medium-sized spindle and epithelioid cells with eosinophilic cytoplasm and round nuclei with finely dispersed chromatin.
  • The tumor cells were surrounded by an abundant mucoid, vacuolated stroma.
  • The periphery of the tumor was enveloped by a significant lymphoplasmacytic infiltrate.
  • The unusual morphology of the tumor caused significant diagnostic difficulties.
  • The differential diagnosis included inflammatory myofibroblastic tumor, spindle cell myoepithelioma, and extraskeletal myxoid chondrosarcoma.
  • To the best of our knowledge, this is possibly the first description of an extracranial or intrapulmonary chordoid meningioma.
  • [MeSH-major] Lung Neoplasms / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry. Male. Microscopy, Electron, Transmission. Middle Aged

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  • (PMID = 15714337.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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79. Moalla J, Charfeddine I, Mnejja M, Hasnaoui M, Chakroun A, Boudaoura MZ, Ghorbel A: [Frontal pneumosinus dilatans associated with multiple cerebral meningioma]. Ann Otolaryngol Chir Cervicofac; 2008 Feb;125(1):30-4
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  • [Title] [Frontal pneumosinus dilatans associated with multiple cerebral meningioma].
  • OBSERVATION: A man, 50 years old, presented frontal pneumosinus dilatans associated with multiple cerebral meningiomas, one of which was appended in the nasal cavity revealed by frontal deformation and nasal obstruction.
  • CT and MRI confirmed the diagnosis.
  • The patient was operated in the neurosurgery department, via the bicoronal approach, allowing the removal of meningioma and osteodural repair of the skull base.
  • Its association with cerebral meningioma has been described in the medical literature.
  • [MeSH-major] Air. Frontal Sinus / radiography. Meningeal Neoplasms / complications. Meningeal Neoplasms / pathology. Meningioma / complications. Meningioma / radiography. Paranasal Sinus Diseases / complications. Paranasal Sinus Diseases / radiography

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  • (PMID = 18313639.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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80. Hwang SL, Liu CS, Su YF, Shen WJ, Chuo CY, Liu GC, Howng SL, Lee KS: Giant nondural-based cauda equina meningioma with multiple cysts. J Neurooncol; 2005 Sep;74(2):173-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant nondural-based cauda equina meningioma with multiple cysts.
  • A very rare case of a giant nondural-based cauda equina meningioma with multiple cysts was presented.
  • Spinal meningioma most commonly occurs in the thoracic or cervical region and typically adheres to the dura.
  • Only six cases of nondural-based meningioma have been reported in English literature.
  • These patients were predominantly female and younger than those with typical intraspinal meningioma.A 46-year-old woman had a 4-year history of lower back pain and right leg pain.
  • Magnetic resonance imaging revealed a giant cauda equina tumor with multiple cysts from T(12) to L(4).
  • Following laminectomies from T(11) to L(5) and intradural exposure, the tumor was found to be draped loosely by the roots of the cauda equina and attached to a root without any firm connection with dura mater.
  • Complete removal of the tumor was achieved after microdissection of arachnoid and sacrifice of an involved rootlet of the cauda equina.
  • The appearance of tumor was that of a typical neurilemmoma.
  • However, histological and immunohistochemical analyses were consistent with meningioma.
  • Nondural-based intraspinal meningiomas are very rare, particularly a giant tumor with multiple cysts as our presenting case.
  • Most of the patients were female and were young, suggesting that the nondural-based cauda equina meningiomas are age- and sex-related.
  • An accurate preoperative and operative diagnosis are difficult.
  • Care must be taken in the management of cauda equina tumors resembling neurilemmoma which may in fact represent meningioma, particularly in the younger female.
  • [MeSH-major] Cauda Equina. Cysts / diagnosis. Dura Mater / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Peripheral Nervous System Neoplasms / diagnosis

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  • (PMID = 16132526.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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81. Cai R, Barnett GH, Novak E, Chao ST, Suh JH: Principal risk of peritumoral edema after stereotactic radiosurgery for intracranial meningioma is tumor-brain contact interface area. Neurosurgery; 2010 Mar;66(3):513-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Principal risk of peritumoral edema after stereotactic radiosurgery for intracranial meningioma is tumor-brain contact interface area.
  • OBJECTIVE: Stereotactic radiosurgery (SRS) of meningiomas is associated with posttreatment peritumoral edema (PTE).
  • The purpose of this study was to evaluate the prevalence and risk factors of post-SRS PTE for intracranial meningiomas.
  • METHODS: A total of 163 patients with 182 meningiomas treated with SRS were retrospectively reviewed.
  • Tumors were divided into 4 pre-SRS groups according to whether they had undergone previous surgery and whether they had preexisting PTE.
  • Several risk factors were investigated by univariate and multivariate analysis in all tumors, tumors without previous surgery, tumors without preexisting PTE, and preexisting PTE.
  • RESULTS: Of 182 tumors, 45 (24.7%) developed post-SRS PTE.
  • Compared with tumors without preexisting PTE, the odds of developing post-SRS PTE in tumors with preexisting PTE were 6.0 times higher in all tumors, and 6.9 times higher in tumors without previous surgery.
  • A 1-cm2 increase in tumor-brain contact interface area increased the odds of developing post-SRS PTE by 17% in all tumors, 16% in tumors without previous surgery, and 26% in tumors without preexisting PTE.
  • Of 118 tumors without previous surgery, 13 had preexisting PTE, the existence of which had a significant relationship to both tumor-brain contact interface area and tumor volume.
  • CONCLUSION: Post-SRS PTE is common in patients with meningioma.
  • Tumor-brain contact interface area and preexisting PTE were the most significant risk factors for post-SRS PTE.
  • Tumor volume and tumor-brain contact interface area were significant risk factors for the development of preexisting PTE.
  • [MeSH-major] Edema / etiology. Meningeal Neoplasms / surgery. Meningioma / surgery. Postoperative Complications / etiology. Radiosurgery / adverse effects
  • [MeSH-minor] Aged. Dose-Response Relationship, Radiation. Female. Follow-Up Studies. Humans. Logistic Models. Magnetic Resonance Imaging / methods. Male. Middle Aged. Neoplasm Recurrence, Local / etiology. Neoplasms, Radiation-Induced / etiology. Retrospective Studies. Risk Factors


82. Bollag RJ, Vender JR, Sharma S: Anaplastic meningioma: progression from atypical and chordoid morphotype with morphologic spectral variation at recurrence. Neuropathology; 2010 Jun;30(3):279-87
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  • [Title] Anaplastic meningioma: progression from atypical and chordoid morphotype with morphologic spectral variation at recurrence.
  • The current WHO 2007 classification divides meningiomas into a 3-grade prognostic hierarchy.
  • Recent literature evokes two pathways to disease progression in meningiomas akin to a comparable paradigm in gliomas, but without similar prognostic connotation: de novo anaplastic meningioma (better prognosis), and transformed meningioma (worse prognosis).
  • We present two adult cases of transformed meningiomas that display a spectrum of morphologic progression.
  • Case 1 at presentation showed a random admixture of meningothelial, atypical and anaplastic meningioma.
  • The tumor recurred as anaplastic meningioma.
  • Case 2 presented as a chordoid meningioma, but recurred as anaplastic meningioma mainly at the invasive front in transition with residual chordoid pattern.
  • Of interest, portions of tumor also showed papillary configuration.
  • In accordance with the dire prognosis for anaplastic meningioma, both patients succumbed to their disease within 2 months of recurrence.
  • The present study highlights two main points: First, that proper recognition of focal high-grade areas in a heterogeneous low-grade meningioma (case 1) provides critical morphologic clues to spatial histologic progression and predicts aggressive biologic behavior, as evidenced by progression to frankly anaplastic meningioma at recurrence.
  • Second, the presence of papillary in addition to anaplastic areas, in the recurrence of a previously diagnosed chordoid meningioma supports the ostensibly heightened transforming potential of grade II meningiomas, but also reflects on the morphologic heterogeneity of high-grade meningiomas, and their potentially diverse pathways of progression.
  • We propose that grading of meningiomas as outlined by WHO is of more critical prognostic import than histologic sub-typing, and must include a thorough survey of the tumor-brain interface.
  • Future molecular genetic correlates, akin to those characterized in gliomas, could help stratify prognostic subcategories to refine meningioma grading, and govern optimal therapeutic strategies.
  • [MeSH-major] Choroid Plexus Neoplasms / diagnosis. Choroid Plexus Neoplasms / pathology. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / pathology. Meningioma / diagnosis. Meningioma / pathology. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Diagnosis, Differential. Disease Progression. Fatal Outcome. Humans. Male. Middle Aged. Prognosis

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  • (PMID = 19780983.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Australia
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83. Ozer E, Kalemci O, Acar UD, Canda S: Pin site metastasis of meningioma. Br J Neurosurg; 2007 Oct;21(5):524-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pin site metastasis of meningioma.
  • Metastasis of meningiomas due to iatrogenic implantation of tumour cells is extremely rare and only four cases have been reported to date.
  • In this study, we report a 45-year-old female patient who presented with meningioma metastasis at the pin site of head holder applied in the original operation.
  • [MeSH-major] Frontal Bone. Meningeal Neoplasms / surgery. Meningioma / secondary. Neoplasm Seeding. Skull Neoplasms / secondary
  • [MeSH-minor] Adult. Cerebrospinal Fluid. Craniotomy / adverse effects. Female. Humans. Neoplasm Recurrence, Local / surgery. Reoperation

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  • (PMID = 17922325.001).
  • [ISSN] 0268-8697
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 5
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84. Kato A, Fujimoto Y, Hashimoto N, Taniguchi M, Kinoshita M, Hirayama A, Maruno M, Yoshimine T: Radiofrequency thermal ablation for recurrent meningioma extending extracranially. Acta Neurochir (Wien); 2005 May;147(5):543-50; discussion 550
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  • [Title] Radiofrequency thermal ablation for recurrent meningioma extending extracranially.
  • BACKGROUND: Image-guided and temperature-controlled radiofrequency thermal ablation techniques were applied to reduce tumor volume and relieve the symptoms caused by extracranial extension of recurrent meningioma.
  • METHOD: We treated two patients with recurrent meningioma, an 81-year-old woman presenting with bulging of the temple and a 68-year-old woman presenting with visual disturbance, facial disfigurement, and sensory disturbance.
  • Neuroimaging in both patients, revealed a large tumor extending extracranially and involving the infratemporal fossa.
  • To avoid injury to important anatomical structures either compressed or entrapped by the tumor, the spatial relation between the planned ablation volume and these structures was confirmed by 3-D reconstruction of the ablation target.
  • FINDING: Radiofrequency ablation produced tumor necrosis as planned without adverse effects and resulted in swift relief of symptoms and signs with shrinkage of the tumor.
  • CONCLUSION: This technique may be an effective alternative for recurrent meningiomas extending extracranially and for which radical surgical procedures are not indicated.
  • [MeSH-major] Catheter Ablation / methods. Meningeal Neoplasms / surgery. Meningioma / surgery. Neoplasm Recurrence, Local / surgery. Skull Base Neoplasms / surgery

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  • (PMID = 15812596.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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85. Cecchi PC, Campello M, Rizzo P, Mair K, Schwarz A: Atypical meningioma of the sylvian fissure. J Clin Neurosci; 2009 Sep;16(9):1234-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical meningioma of the sylvian fissure.
  • Meningiomas are meningothelial cell neoplasms that account for approximately 25% of all primary intracranial tumors.
  • Most meningiomas are slow-growing benign lesions, and they are usually attached to the inner surface of the dura mater.
  • Nevertheless, since the first description by of Cushing and Eisenhardt, many meningiomas without dural attachment have been reported.
  • A subgroup located in the sylvian fissure (also called deep sylvian meningiomas) has been described, and these represent a radiological and neurosurgical challenge.
  • We describe an atypical sylvian fissure meningioma in a 23-year-old male with a brief history of headache and mild hemiparesis.
  • We also review the pertinent literature defining the major epidemiological, clinical, radiological and surgical characteristics of these rare tumors.
  • [MeSH-major] Cerebral Cortex / pathology. Meningioma / pathology

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  • (PMID = 19497747.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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86. Yener U, Bayrakli F, Vardereli E, Sav A, Peker S: Intradiploic meningioma mimicking calvarial metastasis: case report. Turk Neurosurg; 2009 Jul;19(3):297-301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intradiploic meningioma mimicking calvarial metastasis: case report.
  • Meningiomas are the most common benign intracranial neoplasms.
  • Nearly 20% of all primary intracranial tumors are meningiomas.
  • Primary intraosseous meningiomas are a subtype of the meningiomas that represents the most uncommon manifestation of meningiomas.
  • Although rare, these tumors can be found to occur in unexpected areas of the head and neck.
  • Preoperative diagnosis was a metastasis, but histological examination revealed an osteolytic interosseous meningioma.
  • The possibility of an intraosseous meningioma mimicking a metastatic tumor should be kept in mind.
  • [MeSH-major] Meningioma / radionuclide imaging. Neoplasms, Second Primary / radionuclide imaging. Parietal Bone / radionuclide imaging. Skull Neoplasms / radionuclide imaging
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Positron-Emission Tomography. Urinary Bladder Neoplasms / pathology

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  • (PMID = 19621299.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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87. Butte PV, Pikul BK, Hever A, Yong WH, Black KL, Marcu L: Diagnosis of meningioma by time-resolved fluorescence spectroscopy. J Biomed Opt; 2005 Nov-Dec;10(6):064026
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  • [Title] Diagnosis of meningioma by time-resolved fluorescence spectroscopy.
  • We investigate the use of time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) as an adjunctive tool for the intraoperative rapid evaluation of tumor specimens and delineation of tumor from surrounding normal tissue.
  • Experiments are conducted on excised specimens (meningioma, dura mater, cerebral cortex) from 26 patients (97 sites).
  • Our results reveal that meningioma is characterized by unique fluorescence characteristics that enable discrimination of tumor from normal tissue with high sensitivity (>89%) and specificity (100%).
  • Our findings establish the feasibility of using TR-LIFS as a tool for the identification of meningiomas and enables further development of real-time diagnostic tools for analyzing surgical tissue specimens of meningioma or other brain tumors.

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  • (PMID = 16409091.001).
  • [ISSN] 1083-3668
  • [Journal-full-title] Journal of biomedical optics
  • [ISO-abbreviation] J Biomed Opt
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / HL067377-01; United States / NHLBI NIH HHS / HL / R01 HL067377; United States / NHLBI NIH HHS / HL / R01 HL067377-01
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS245430; NLM/ PMC2981341
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88. Wiemels J, Wrensch M, Claus EB: Epidemiology and etiology of meningioma. J Neurooncol; 2010 Sep;99(3):307-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiology and etiology of meningioma.
  • Although most meningiomas are encapsulated and benign tumors with limited numbers of genetic aberrations, their intracranial location often leads to serious and potentially lethal consequences.
  • They are the most frequently diagnosed primary brain tumor accounting for 33.8% of all primary brain and central nervous system tumors reported in the United States between 2002 and 2006.
  • Inherited susceptibility to meningioma is suggested both by family history and candidate gene studies in DNA repair genes.
  • People with certain mutations in the neurofibromatosis gene (NF2) have a very substantial increased risk for meningioma.
  • High dose ionizing radiation exposure is an established risk factor for meningioma, and lower doses may also increase risk, but which types and doses are controversial or understudied.
  • Because women are twice as likely as men to develop meningiomas and these tumors harbor hormone receptors, an etiologic role for hormones (both endogenous and exogenous) has been hypothesized.
  • The extent to which immunologic factors influence meningioma etiology has been largely unexplored.
  • Growing emphasis on brain tumor research coupled with the advent of new genetic and molecular epidemiologic tools in genetic and molecular epidemiology promise hope for advancing knowledge about the causes of intra-cranial meningioma.
  • In this review, we highlight current knowledge about meningioma epidemiology and etiology and suggest future research directions.

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  • (PMID = 20821343.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA109468; United States / NCI NIH HHS / CA / R01 CA109745-05; United States / NCI NIH HHS / CA / R01 CA109745-04; United States / NCI NIH HHS / CA / CA109745; United States / NCI NIH HHS / CA / CA52689; United States / NCI NIH HHS / CA / R01 CA109468; United States / NCI NIH HHS / CA / R01 CA109745-03; United States / NCI NIH HHS / CA / CA109461; United States / NCI NIH HHS / CA / R01 CA151933; United States / NCI NIH HHS / CA / P50 CA097257; United States / NCI NIH HHS / CA / CA108473; United States / NCI NIH HHS / CA / CA097257; United States / NCI NIH HHS / CA / R01 CA109461; United States / NCI NIH HHS / CA / R01 CA109745-02; United States / NCI NIH HHS / CA / R01 CA109475; United States / NCI NIH HHS / CA / R01 CA109745; United States / NCI NIH HHS / CA / CA109475; United States / NCI NIH HHS / CA / R01 CA052689
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2945461
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89. Kumar R, Kamdar D, Madden L, Hills C, Crooks D, O'Brien D, Greenman J: Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients. Oncol Rep; 2006 Jun;15(6):1513-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients.
  • Serum samples from 61 newly diagnosed patients with brain tumours and 50 age- and sex-matched non-tumour controls were analysed by ELISA for circulating levels of interleukin-12 (IL-12p70 and p40) and interleukin-10 (IL-10); pivotal Th1 and Th2 cytokines, respectively.
  • Patients were divided into various groups depending on their histological diagnosis: meningioma (n=11), anaplastic astrocytoma (n=4) and glioblastoma multiforme (GBM; n=46).
  • Significant reduction in serum IL-12 was seen in all groups as compared with the controls: meningioma, p=0.03; anaplastic astrocytoma, p<0.001; and GBM, p<0.001.
  • This study shows that patients with advanced primary intracranial malignancies have decreased circulating IL-12 and increased circulating IL-10, demonstrating that brain tumours have a major systemic effect on the immune system.
  • [MeSH-major] Astrocytoma / immunology. Brain Neoplasms / immunology. Glioblastoma / immunology. Interleukin-10 / blood. Interleukin-12 / blood. Meningioma / immunology. Th1 Cells / immunology. Th2 Cells / immunology


90. Basu K, Majumdar K, Chatterjee U, Ganguli M, Chatterjee S: En plaque meningioma with angioinvasion. Indian J Pathol Microbiol; 2010 Apr-Jun;53(2):319-21
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  • [Title] En plaque meningioma with angioinvasion.
  • En plaque meningioma is a rare type of meningioma characterized by infiltrative nature, sheet-like growth and at times invading the bone.
  • We report here a case of en plaque meningioma with typical grade I histomorphology along with unusual feature of angioinvasion.
  • Imaging modalities revealed an en -plaque meningioma extending into the right sylvian fissure, with thickening of right temporal calvarium, greater wing of sphenoid and extension into the orbit.
  • The tumor was removed from the sylvian fissure and right temporal convexity.
  • Histology showed a meningothelial meningioma with low tumor cell proliferation, but infiltration into the bone, skeletal muscle and angioinvasion.
  • Recognition of meningiomas en plaque is useful, as these tumors are difficult to resect completely, and are more prone to undergo recurrence or malignant change.
  • In addition, angioinvasion seen in this tumor may have additional prognostic significance.
  • [MeSH-major] Meningioma / diagnosis. Meningioma / pathology. Neovascularization, Pathologic
  • [MeSH-minor] Angiography. Brain / radiography. Exophthalmos / pathology. Histocytochemistry. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Microscopy. Middle Aged

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  • (PMID = 20551544.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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91. Eghwrudjakpor PO, Mori K: Sylvian cleft meningioma: surgical approach and postoperative morbidity. Niger J Med; 2006 Oct-Dec;15(4):437-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sylvian cleft meningioma: surgical approach and postoperative morbidity.
  • BACKGROUND: Meningiomas without dural attachments are rare, and are commonly diagnosed postoperatively.
  • We here report a case of meningioma and examine the surgical options.
  • METHOD: We reviewed the case record of the patient who presented with a right sylvian cleft meningioma as well as relevant literature on the subject.
  • RESULT: Brain CT scan performed on a 73-year-old woman on admission for non-specific symptoms revealed. a heterodense temporoparietal mass which was demonstrated on carotid angiography as being fed by the middle cerebral artery.
  • The mass, which at surgery was found to be located in the sylvian fissure, was however histologically confirmed to be a meningotheliomatous meningioma with fibroblastic component CONCLUSION: The surgical approach to meningioma of the sylvian cleft is a prime determinant of outcome following tumour resection.
  • Making an appropriate approach largely depends on making a correct preoperative diagnosis for which a high index of suspicion is necessary.
  • [MeSH-major] Glioblastoma / diagnosis. Glioblastoma / surgery. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / surgery. Meningioma / diagnosis. Meningioma / surgery

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  • (PMID = 17111734.001).
  • [ISSN] 1115-2613
  • [Journal-full-title] Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria
  • [ISO-abbreviation] Niger J Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nigeria
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92. Saraceni C, Harrop JS: Spinal meningioma: chronicles of contemporary neurosurgical diagnosis and management. Clin Neurol Neurosurg; 2009 Apr;111(3):221-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal meningioma: chronicles of contemporary neurosurgical diagnosis and management.
  • Spinal meningiomas are uncommon entities that fortunately burden only a small minority of patients.
  • Notwithstanding their overwhelmingly benign propensity, the occurrence of extramedullary meningioma may nonetheless cause significant morbidity and possible mortality.
  • The consideration therefore, of spinal meningioma in the differential of patients presenting with radiculopathy or complaints of chronic back or neck pain should not be disregarded.
  • The rapidity of diagnosis and the first neurosurgical encounter are cornerstones in patient longevity and neurological preservation.
  • However, surgical candidacy may be limited, particularly in those patients with significant preexisting medical comorbidities, aggressive or recurring tumors, or multiple lesions.
  • A review on neurosurgical diagnosis and treatment modalities in the management of spinal meningioma is therefore pertinent.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / surgery. Meningioma / diagnosis. Meningioma / surgery. Microsurgery / methods. Radiosurgery / methods


93. Rao S, Rajkumar A, Kuruvilla S: Angiomatous meningioma: a diagnostic dilemma. Indian J Pathol Microbiol; 2008 Jan-Mar;51(1):53-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomatous meningioma: a diagnostic dilemma.
  • Angiomatous meningioma accounts for 2.1% of all meningiomas.
  • It has features of a typical benign meningioma with many small or large vascular channels which may predominate over its meningothelial elements.
  • We present here a series of three cases of angiomatous meningioma, which posed diagnostic difficulty to clinicians, radiologists, and pathologists.
  • All the three cases showed a tumor entirely composed of thin-walled vascular channels and cells with bland morphology in the background.
  • The diagnosis was confirmed by immunohistochemistry.
  • We present series of three cases to highlight the histomorphological features of this uncommon variant of meningioma that could help in distinguishing it from hemangioblastoma and hemangiopericytoma.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Hemangioblastoma / diagnosis. Hemangiopericytoma / diagnosis. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18417856.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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94. Shintaku M, Honda T, Sakai T: Expression of podoplanin and calretinin in meningioma: an immunohistochemical study. Brain Tumor Pathol; 2010 Apr;27(1):23-7
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  • [Title] Expression of podoplanin and calretinin in meningioma: an immunohistochemical study.
  • Meningioma is derived from arachnoid cells covering the surface of the brain and spinal cord, and it has characteristics shared by mesothelioma arising from the pleura and peritoneum in that it takes an epithelioid appearance despite its mesenchymal origin.
  • We examined the immunohistochemical expression of podoplanin and calretinin, both of which are well-known markers of mesothelioma, in 24 surgical cases of meningioma of various types.
  • These findings indicate that podoplanin can be used as an immunohistochemical marker that is equivalent to EMA in the differential diagnosis of meningioma.
  • However, most meningiomas did not contain calretinin-immunoreactive cells, a finding that differs from the diffuse immunoreactivity seen in mesothelioma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Membrane Glycoproteins / analysis. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. S100 Calcium Binding Protein G / analysis
  • [MeSH-minor] Aged. Calbindin 2. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Mucin-1 / analysis

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  • (PMID = 20425044.001).
  • [ISSN] 1861-387X
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / Membrane Glycoproteins; 0 / Mucin-1; 0 / PDPN protein, human; 0 / S100 Calcium Binding Protein G
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95. Davis F, Tavelin B, Grutsch J, Malmer B: Second primary tumors following a diagnosis of meningioma in Sweden, 1958-1997. Neuroepidemiology; 2007;29(1-2):101-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Second primary tumors following a diagnosis of meningioma in Sweden, 1958-1997.
  • This study quantifies the risk of second primary tumors following a diagnosis of meningioma.
  • 12,012 meningiomas and 926 second primary cancers were identified (ICD7, path code 461) between 1958 and 1997 using Swedish Cancer Registry data.
  • An elevated risk of any second primary cancer diagnosis (SIR = 1.2, 95% CI = 1.1-1.3) was observed.
  • Elevated and statistically significant SIRs were observed for renal cancer (SIR = 1.6), melanoma (SIR = 1.7), thyroid cancer (SIR = 2.6) and brain tumors (SIR = 2.6).
  • Radiation exposures increase the risk of these rare tumors, so quantifying the cumulative and shared effects of environmental and treatment exposures is of further interest.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Neoplasms, Second Primary / epidemiology. Neoplasms, Second Primary / pathology

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  • [Copyright] (c) 2007 S. Karger AG, Basel.
  • (PMID = 17940341.001).
  • [ISSN] 1423-0208
  • [Journal-full-title] Neuroepidemiology
  • [ISO-abbreviation] Neuroepidemiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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96. Tekkök IH, Cinel L, Zorludemir S: Intraparenchymal meningioma. J Clin Neurosci; 2005 Jun;12(5):605-8
Genetic Alliance. consumer health - Meningioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraparenchymal meningioma.
  • Preliminary diagnosis was cerebral metastasis.
  • Histopathology and immunohistochemistry showed the mass to be an intraparenchymal meningioma, which is rare.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Temporal Lobe / pathology
  • [MeSH-minor] Arachnoid / pathology. Brain Edema / etiology. Brain Edema / physiopathology. Central Nervous System Cysts / etiology. Central Nervous System Cysts / physiopathology. Cerebral Arteries / pathology. Diagnosis, Differential. Female. Headache / etiology. Headache / physiopathology. Humans. Magnetic Resonance Imaging. Middle Aged. Neurosurgical Procedures. Pia Mater / pathology. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15993076.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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97. Alexiou GA, Vartholomatos G, Tsiouris S, Papadopoulos A, Kyritsis AP, Polyzoidis KS, Voulgaris S, Fotopoulos AD: Evaluation of meningioma aggressiveness by (99m)Tc-Tetrofosmin SPECT. Clin Neurol Neurosurg; 2008 Jul;110(7):645-8
Genetic Alliance. consumer health - Meningioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of meningioma aggressiveness by (99m)Tc-Tetrofosmin SPECT.
  • OBJECTIVES: Although meningiomas usually have a benign clinical course, atypical and malignant types of this brain tumor are associated with high recurrence rates and poor outcome; thus, DNA ploidy and S-phase -- as determined by DNA flow cytometry -- are useful indicators of their biological behavior.
  • Brain single-photon emission computed tomography (SPECT) has been suggested as a potentially useful modality for the metabolic assessment of various brain tumors.
  • This study evaluated whether (99m)Tc-Tetrofosmin ((99m)Tc-TF) uptake correlates with meningioma proliferative activity, as assessed by flow cytometry analysis.
  • PATIENTS AND METHODS: Ten consecutive patients (3 males, 7 females, mean age 64.6 years) with a diagnosis of a symptomatic intracranial meningioma, planned to undergo surgery, were studied.
  • Brain SPECT by (99m)Tc-TF was performed within a week prior to surgical excision and flow cytometric analysis was performed in the excised tissue.
  • RESULTS: Benign meningiomas were diagnosed in 8/10 cases, the remaining 2/10 patients had anaplastic lesions.
  • DNA aneuploidy was found in 2 lesions, the remaining tumors were diploid.
  • There was also a positive correlation between tracer uptake and the level of aneuploidy and tumor grade.
  • CONCLUSION: These results imply that (99m)Tc-TF brain SPECT may have the ability to discriminate benign meningiomas from malignant meningiomas pre-operatively, the tracer uptake being a likely indicator of their proliferative activity.
  • [MeSH-major] Meningeal Neoplasms / radionuclide imaging. Meningioma / radionuclide imaging. Organophosphorus Compounds. Organotechnetium Compounds. Tomography, Emission-Computed, Single-Photon / methods
  • [MeSH-minor] Aged. Cell Cycle. Female. Flow Cytometry. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Reproducibility of Results. Tomography, X-Ray Computed

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  • (PMID = 18471956.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Organophosphorus Compounds; 0 / Organotechnetium Compounds; 0 / technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane
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98. Umansky F, Shoshan Y, Rosenthal G, Fraifeld S, Spektor S: Radiation-induced meningioma. Neurosurg Focus; 2008;24(5):E7
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for radiation induced meningioma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiation-induced meningioma.
  • In the present article the authors review the literature relating to radiation-induced meningiomas (RIMs).
  • Emphasis is placed on meningiomas resulting from childhood treatment for primary brain tumor or tinea capitis, exposure to dental x-rays, and exposure to atomic explosions in Hiroshima and Nagasaki.
  • The authors review the typical presentation of patients with RIMs and discuss unique aspects of the surgical management of these tumors compared with sporadic meningioma, based on their clinical experience in treating these lesions.
  • [MeSH-major] Cranial Irradiation / adverse effects. Meningeal Neoplasms / etiology. Meningioma / etiology. Neoplasms, Radiation-Induced / etiology
  • [MeSH-minor] Adolescent. Adult. Alopecia / etiology. Brain Neoplasms / radiotherapy. Child. Cohort Studies. Dose-Response Relationship, Radiation. Female. Humans. Japan / epidemiology. Male. Neoplasm Invasiveness. Neoplasms, Second Primary / etiology. Neoplasms, Second Primary / radiotherapy. Neoplasms, Second Primary / surgery. Nuclear Warfare. Radiation Injuries / epidemiology. Radiation Injuries / etiology. Radiation Injuries / prevention & control. Radiography, Dental / adverse effects. Radiosurgery / adverse effects. Radiotherapy / trends. Tinea Capitis / radiotherapy

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  • [CommentIn] Neurosurg Focus. 2008;24(5):E6; discussion E6 [18447745.001]
  • (PMID = 18447746.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article; Portraits; Review
  • [Publication-country] United States
  • [Number-of-references] 82
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99. Vranic A: Antigen expression on recurrent meningioma cells. Radiol Oncol; 2010 Jun;44(2):107-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Antigen expression on recurrent meningioma cells.
  • INTRODUCTION: Meningiomas are intracranial brain tumours that frequently recur.
  • Recurrence rates up to 20% in 20 years for benign meningiomas, up to 80% for atypical meningiomas and up to 100% for malignant meningiomas, have been reported.
  • The most important prognostic factors for meningioma recurrence are meningioma grade, meningioma invasiveness and radicality of neurosurgical resection.
  • The aim of our study was to evaluate the differences in antigenic expression on the surface of meningioma cells between recurrent and non-recurrent meningiomas.
  • METHODS: 19 recurrent meningiomas and 35 non-recurrent meningiomas were compared regarding the expression of MIB-1 antigen, progesterone receptors, cathepsin B and cathepsin L, using immunohistochemistry.
  • RESULTS: MIB-1 antigen expression was higher in the recurrent meningioma group (p=0.001).
  • No difference in progesterone receptor status between recurrent and non-recurrent meningiomas was confirmed.
  • Immunohistochemical intensity scores for cathepsin B (p= 0.007) and cathepsin L (p<0.001) were both higher in the recurrent than in the non-recurrent meningioma group.
  • CONCLUSIONS: [corrected] MIB-1 antigen expression is higher in recurrent compared to non-recurrent meningiomas.
  • There is no difference in expression of progesterone receptors between recurrent and non-recurrent meningiomas.
  • Cathepsins B and L are expressed more in recurrent meningiomas.

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  • (PMID = 22933900.001).
  • [ISSN] 1318-2099
  • [Journal-full-title] Radiology and oncology
  • [ISO-abbreviation] Radiol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Slovenia
  • [Other-IDs] NLM/ PMC3423683
  • [Keywords] NOTNLM ; cathepsin B / cathepsin L / meningioma / proliferation index, MIB-1 antigen / recurrence / tumour markers
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100. Geng SM, Zhang JT, Zhang LW, Wu Z, Wang ZC: Optimal microsurgical treatment of dorsum sellae meningioma. Chin Med J (Engl); 2009 Aug 20;122(16):1857-61
Genetic Alliance. consumer health - Meningioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optimal microsurgical treatment of dorsum sellae meningioma.
  • BACKGROUND: There are few reports of microsurgical treatment of dorsum sellae meningiomas-which, because of location, size, and differences in growth direction, clinical presentations, degree of surgical difficulty, have varied posttreatment sequelae.
  • In pursuit of an optimal microsurgical treatment option for dorsum sellae meningioma patients, we performed a retrospective analysis of eight microsurgery-treated patients in our set up.
  • METHODS: Clinical data of eight microsurgery-treated dorsum sellae meningioma patients were analyzed.
  • Dorsum sellae meningiomas were classified into 2 types based on tumor location, size, and direction of growth.
  • Type I tumors (dorsum sellae-inferior third ventricle type, four cases) were resected by craniotomy via the frontotemporal or orbitozygomatic approach.
  • Type II tumors (dorsum sellae-third ventricle type, 4 cases) were resected by frontal craniotomy via the transcallosal-interforniceal approach.
  • RESULTS: Complete tumor resection was achieved in all the eight patients.
  • In Type I tumor patients, the only postoperative complication was oculomotor nerve palsy.
  • In Type II tumor patients, the postoperative complications included hyperthermia, electrolyte imbalances, endocrinologic disturbances, and hydrocephalus.
  • CONCLUSIONS: Dorsum sellae meningioma surgery is challenging, and resection of Type II tumors is more difficult than Type I tumors.
  • The selection of a suitable microsurgical approach based on tumor type, and the active treatment of postoperative complications are important means of increasing therapeutic efficacy.
  • [MeSH-major] Meningeal Neoplasms / surgery. Meningioma / surgery. Microsurgery / methods

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  • (PMID = 19781360.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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