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[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Analysis of misdiagnosis of calcifying epithelioma in oral and maxillofacial-head and neck region].

Eight patients misdiagnosed as calcifying epithelioma during 2003-2008 at Department of Oral and Maxillofacial Surgery of Cangzhou Central Hospital were retrospectively analyzed.

The pertinent literatures were reviewed and the pathogenesis, clinical manifestations, imaging performance and differential diagnosis of calcifying epithelioma were discussed.

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(PMID = 20848947.001).

[ISSN] 1000-1182

[Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

[ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi

[Language] chi

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] China

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Epithelioma of Malherbe: new ultrasound patterns.

BACKGROUND: Calcifying epithelioma of Malherbe, or Pilomatricoma, is considered an uncommon cutaneous neoplasia, normally occurring in children as a solitary, firm, asymptomatic, hard, subcutaneous, slowly growing nodule on the face, neck, or proximal upper extremity.

[MeSH-major] Carcinoma / ultrasonography. Hair Diseases / ultrasonography. Pilomatrixoma / ultrasonography. Skin Neoplasms / ultrasonography

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(PMID = 20444298.001).

[ISSN] 1756-9966

[Journal-full-title] Journal of experimental & clinical cancer research : CR

[ISO-abbreviation] J. Exp. Clin. Cancer Res.

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Other-IDs] NLM/ PMC2883973

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Transliterated title] Epithelioma Spinocellulaire sur Cicatrice de Brulure (a Propos de Cinq Cas).

In order to study Marjolin's ulcer, all the case histories of patients admitted over a 5-yr period to a Service of Plastic Surgery and Burn Patients in Morocco presenting a histopathologically confirmed burn scar cancer were included in a data file with information regarding the medical background of the five patients concerned, their treatment, and the evolution of the case.After this data presentation, the problems set by spinocellular epithelioma, which is a serious and rare affection, are considered.The degeneration of burn scars is a dramatic development, caused by negligence.

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(PMID = 21991185.001).

[ISSN] 1592-9566

[Journal-full-title] Annals of burns and fire disasters

[ISO-abbreviation] Ann Burns Fire Disasters

[Language] fre

[Publication-type] English Abstract; Journal Article

[Publication-country] Italy

   

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[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Multiple self-healing squamous epithelioma in different ethnic groups: more than a founder mutation disorder?

Multiple self-healing squamous epithelioma (MSSE), also known as Ferguson-Smith Disease, is a rare cancer-associated genodermatosis with an autosomal dominant inheritance.

[MeSH-major] Carcinoma / ethnology. Carcinoma / genetics. Founder Effect. Mutation / genetics. Skin Neoplasms / ethnology. Skin Neoplasms / genetics

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(PMID = 17554363.001).

[ISSN] 1523-1747

[Journal-full-title] The Journal of investigative dermatology

[ISO-abbreviation] J. Invest. Dermatol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Multiple self-healing squamous epithelioma of Ferguson-Smith: observations in a Danish family covering four generations.

Multiple self-healing squamous epithelioma of Ferguson-Smith (MSSE) is a rare autosomal dominantly inherited disease, almost exclusively reported in patients of Scottish origin, with recurrent, histologically malignant tumours that undergo spontaneous regression.

Anamnestic data and data concerning age of onset, localization, number of tumours and treatment modalities were collected from the family and from medical records, and all living patients were examined.

A total of 44 tumours, chiefly located in sun-exposed areas, were recorded and the average number of tumours per patient was 4 (range 1-23).

61.4% of the tumours were excised, 31.8% regressed spontaneously without treatment.

MSSE constitutes an important model for research into tumour biology.

[MeSH-major] Carcinoma, Squamous Cell / genetics. Keratoacanthoma / genetics. Skin Neoplasms / genetics

[MeSH-minor] Adult. Aged. Aged, 80 and over. Denmark. Facial Neoplasms / genetics. Facial Neoplasms / pathology. Female. Genetic Predisposition to Disease. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Regression, Spontaneous. Pedigree

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(PMID = 18176752.001).

[ISSN] 0001-5555

[Journal-full-title] Acta dermato-venereologica

[ISO-abbreviation] Acta Derm. Venereol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Sweden

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Epithelioma calcificans malherbe].

Authors described the case of familial occurrence of epithelioma calcificans Malherbe (pilomatricoma) in 6-year-old boy and his 68-year-old grandfather.

Tumors were clinically diagnosed as atheromas of nucha and shoulder.

[MeSH-major] Hair Diseases / pathology. Head and Neck Neoplasms / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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(PMID = 17607978.001).

[ISSN] 0043-5147

[Journal-full-title] Wiadomości lekarskie (Warsaw, Poland : 1960)

[ISO-abbreviation] Wiad. Lek.

[Language] pol

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Poland

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Calcifying epithelioma in the neck: report of one case].

Calcifying epithelioma is one kind of benign tumour,which rarely happens in the neck.

The clinical diagnosis of calcifying epithelioma is difficult and misdiagnosis is common.

This paper reported one case of calcifying epithelioma in the neck, and discussed its clinical features and therapy based on literature review.

[MeSH-major] Head and Neck Neoplasms. Skin Neoplasms

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(PMID = 20143035.001).

[ISSN] 1006-7248

[Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology

[ISO-abbreviation] Shanghai Kou Qiang Yi Xue

[Language] chi

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] China

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Dermatopathology in historical perspective: epithelioma cuniculatum (Aird).

Professor Ian Aird, a renowned British surgeon of the mid-twentieth century, described a peculiar neoplasm of the foot in 3 patients under the term epithelioma cuniculatum, now more commonly called carcinoma cuniculatum.

I will recount the life of Professor Aird and then summarize his original report emphasizing the clinical and more particularly the histopathologic criteria of epithelioma cuniculatum as described by Aird et al.

Then I will summarize some of the subsequent reports of epithelioma (carcinoma) cuniculatum.

Authors have grouped carcinoma cuniculatum with giant condyloma of the penis of Buschke-Loewenstein and oral verrucous carcinoma of Ackerman and similar neoplasms at other sites under the generic title "verrucous carcinoma."

If a neoplasm on the foot has the characteristics of verrucous carcinoma that occurs at others sites, but not those of Aird et al, it should be called verrucous carcinoma of the foot, and not "epithelioma (carcinoma) cuniculatum. "

[MeSH-major] Carcinoma, Verrucous / history. Carcinoma, Verrucous / pathology. Dermatology / history. Pathology, Surgical / history. Skin Neoplasms / history. Skin Neoplasms / pathology

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(PMID = 17012926.001).

[ISSN] 0193-1091

[Journal-full-title] The American Journal of dermatopathology

[ISO-abbreviation] Am J Dermatopathol

[Language] eng

[Publication-type] Biography; Historical Article; Journal Article; Portraits

[Publication-country] United States

[Personal-name-as-subject] Aird I

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Tricho-epithelioma multiplex: two cases reports].

[Transliterated title] Les tricho-epithéliomes multiples: a propos de deux observations.

Tricho-epitheliomas are benign tumors of the pilosebaccous apparatus.

Multiple tricho-epithelioma form is particular.

Treatment was local excision of tumors.

Multiple tricho-epitheliomas is a genodermatosis it is often associated to other benign cutaneous tumors, mainly cylindromas and spiradenomas.

[MeSH-major] Carcinoma / pathology. Carcinoma / surgery. Skin Neoplasms / pathology. Skin Neoplasms / surgery

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(PMID = 17256419.001).

[ISSN] 0035-3639

[Journal-full-title] Revue médicale de Bruxelles

[ISO-abbreviation] Rev Med Brux

[Language] fre

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Belgium

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Ulceroproliferative growth on the heel: epithelioma cuniculatum.

We present a patient with an ulceroproliferative growth on the heel which was found to represent the epithelioma cuniculatum form of squamous cell carcinoma.

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(PMID = 17083863.001).

[ISSN] 1087-2108

[Journal-full-title] Dermatology online journal

[ISO-abbreviation] Dermatol. Online J.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Recalcitrant verrucous lesion: verrucous hyperplasia or epithelioma cuniculatum (verrucous carcinoma).

Verrucous lesions can be frustrating, and the diagnosis of epithelioma cuniculatum can be difficult to prove.

We report a case highly suggestive of but not definitively diagnosed as epithelioma cuniculatum and summarize the literature on this entity.

[MeSH-major] Carcinoma, Verrucous / diagnosis. Foot Diseases / pathology. Skin Neoplasms / diagnosis

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(PMID = 16546953.001).

[ISSN] 8750-7315

[Journal-full-title] Journal of the American Podiatric Medical Association

[ISO-abbreviation] J Am Podiatr Med Assoc

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Epithelioma cuniculatum: A case report.

Epithelioma cuniculatum (carcinoma cuniculatum) is a rare, low-grade verrucous carcinoma of the foot first described in 1954.

Epithelioma cuniculatum presents as a slow growing mass on the plantar aspect of the foot.

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(PMID = 19410181.001).

[ISSN] 1460-9584

[Journal-full-title] Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons

[ISO-abbreviation] Foot Ankle Surg

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] France

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Face necrotizing fasciitis following spinocellular epithelioma excision].

[Transliterated title] Fasciite nécrosante de la face après exérèse d'un épithélioma spinocellulaire.

A 86 year-old Caucasian male without any antecedents, nor treatment, has been operated for a fronthead spinocellular epithelioma under local anesthesia.

[MeSH-major] Carcinoma / surgery. Fasciitis, Necrotizing / etiology. Fasciitis, Necrotizing / surgery. Postoperative Complications / etiology. Postoperative Complications / surgery. Skin Neoplasms / surgery. Streptococcus pyogenes / isolation & purification

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(PMID = 15963844.001).

[ISSN] 0294-1260

[Journal-full-title] Annales de chirurgie plastique et esthétique

[ISO-abbreviation] Ann Chir Plast Esthet

[Language] fre

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] France

[Chemical-registry-number] 0 / Anti-Bacterial Agents

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

IFNg transcript activity was low in the entire cohort and limited to tumor epithelial cells.

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(PMID = 27963334.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Gemcitabine-capecitabine in platinum-refractory patients with thymic epithelial tumors.

: 7590 Background: Platinum based combination chemotherapy is the actual standard of care for advanced and recurrent Thymic epithelial tumours-TET (thymoma and thymic carcinoma).

Tumors were classified by WHO classification as follows: 4-B2, 8-B2/B3.

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(PMID = 27963403.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Analysis of cell surface erythropoietin receptor (EpoR) expression and function in human epithelial tumor tissues.

: 11104 Background: EpoR mRNA and protein expression have been reported at low levels in human tumors implying EpoR may be functional in tumor cells with inferred implications for the use of erythropoiesis stimulating agents in the Oncology setting.

However, mRNA studies use bulk tumor tissue which ignores contribution from the stroma and IHC studies have all used Abs that have since been shown to not be specific for EpoR.

METHODS: EpoR expression and function was investigated in viable, non-apoptotic primary human tumor cells (using tumor specific Abs) that were disaggregated from at least 30 patients from each of the following tumor types: breast (incl. metastases), NSC lung, colorectal, and ovarian.

Additional tumor types included head and neck, GBM, pancreatic and gastric.

RESULTS: No expression of cell surface EpoR was detected in tumor cells in any of the over 130 tumors.

No induction of EpoR signaling was observed in tumor cells at any [Epo], whereas activation was readily detected in tumor cells treated in parallel with a cocktail of known tumor growth factors.

No evidence of EpoR expression or function was observed in tumor endothelial cells.

CONCLUSIONS: These data demonstrate that epithelial tumor cells do not express functional cell surface EpoR and are not responsive to physiological, therapeutic or indeed very high levels of Epo (300U/mL).

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(PMID = 27963466.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Gauging the response of circulating epithelial tumor cells (CETC) and tumor stem cell subpopulations to therapy of early-stage cancer in the individual patient.

: 11026 Background: Cells released from the primary tumor persisting and recirculating in the host can lead to the formation of distant metastases.

METHODS: Using anticoagulated peripheral blood, red blood cell lysis as the only enrichment step, one centrifugation step, staining live cells with fluorochrome labelled anti-epithelial antigen as a search antibody, automated image analysis for detection of positive events and evaluation of exclusively surface located epithelial antigen on vital unfixed cells, CETC were detected in most patients with early stage cancer.

CONCLUSIONS: CETC and subpopulation monitoring provides an invaluable tool for prompt gauging of systemic therapy in early stage solid tumors as a tool for therapy guidance and optimal personalized therapies to improve therapy results and spare unnecessary treatments.

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(PMID = 27963971.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

: e14000 Background: Parsons et al. (ASCO 2008) reported the results of a pivotal phase II/III trial in patients with malignant ascites due to epithelial cancer.

METHODS: A post-hoc analysis was performed on the 258 patients with epithelial tumors treated with catumaxomab + paracentesis or paracentesis alone (control) in the pivotal trial to investigate any association between the primary endpoint (puncture-free survival) and the primary tumor, metastases, or other prognostic parameters.

RESULTS: Puncture-free survival was lower in patients with non-ovarian vs ovarian tumors and those with a poor prognosis (metastases vs no metastases, elderly vs younger, or low vs serum protein level).

CONCLUSION: Catumaxomab demonstrated a significant clinical benefit in patients with malignant ascites independent of the primary tumor or other prognostic factors.

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(PMID = 27961494.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Localization of erythropoietin receptor mRNA in primary breast tumors by laser capture microdissection.

: e22036 Background: Adverse effects of erythropoiesis stimulating agents on tumor progression and/or survival were observed in recent Phase III clinical trials, however, mechanisms are not understood.

Whether tumor erythropoietin receptor (EpoR) expression is associated with erythropoietin-dependent tumor progression remains unclear, owing in part to the lack of specificity of commercial antibodies for protein detection.

To overcome issues of protein detection, we previously optimized a quantitative RTPCR approach for reliable measurements of low level EpoR mRNA in primary tumor samples, and observed a 30-fold range of EpoR expression among panels of both breast and head and neck cancer samples.

METHODS: To test whether EpoR mRNA is expressed in tumor epithelial cells, we performed laser capture microdissection to fractionate 3 breast tumors into tumor epithelial enriched vs. depleted fractions.

RESULTS: Vascular endothelial markers in tumor epithelial-enriched fractions were reduced by an average of 15.3-fold (vascular endothelial cadherin) and 18.5-fold (platelet cell adhesion molecule 1) while the stromal marker vimentin was reduced by 14.7-fold.

EpoR expression was enriched by 4.9-, 7.2-, and 1.1-fold in epithelial enriched fractions.

CONCLUSIONS: Despite the depletion of endothelial cells, EpoR mRNA was at the same level or enriched in tumor epithelial fractions.

These results demonstrate that malignant epithelial cells are a major source of EpoR mRNA in primary tumors.

Applying this approach to additional breast cancer specimens as well as other cancer types will improve our understanding of erythropoietin-associated tumor progression.

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(PMID = 27963153.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Inhibition by lenalidomide of growth factor and hypoxia-induced signaling in endothelial and epithelial tumor cells, and effects within the tumor cell microenvironment.

It has direct anti-proliferative activity in hematological cells but there is no evidence of direct activity in solid tumor cells.

In solid tumors, lenalidomide is being advanced in combination with other agents to take advantage of its immune-enhancing properties in combination with direct anti-tumor agents.

Lysophosphatidic acid (LPA) is a key pro-survival factor present at high levels within the ascites of ovarian cancer patients which confers increased tumor invasiveness and reduced survival.

Hypoxia-induced factor (HIF)-1α is the key initiator of angiogenesis and tumor invasiveness.

The effect of lenalidomide on HIF-1α expression by endothelial cells and epithelial cells was also investigated.

Treatment of ovarian tumor cells with LPA increased tumor cell invasiveness via enhanced p-Akt.

Hypoxic endothelial cells and epithelial tumor cells showed enhanced HIF-1α expression.

Lenalidomide inhibited hypoxia-induced HIF-1α expression by endothelial cells and by epithelial tumor cells, including prostate, breast, pancreatic, renal and ovarian tumor cells.

CONCLUSIONS: Lenalidomide may act within the tumor microenvironment to inhibit key signals of tumor cells survival, growth, and invasiveness.

These studies support the potential utility of lenalidomide in combination with other agents in the treatment of patients with solid tumors.

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(PMID = 27964203.001).

[ISSN] 1527-7755

[Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[ISO-abbreviation] J. Clin. Oncol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Transliterated title] Modalităti de acoperire într-un caz de carcinom verucos plantar (Epithelioma cuniculatum).

Carcinoma verrucous--anatomoclinical entity histological high rate of differentiation of the spinocellular epithelioma, clinically associated with 3 types of lesion.

[MeSH-major] Calcaneus. Carcinoma, Verrucous / surgery. Muscle, Skeletal / transplantation. Neoplasm Recurrence, Local. Soft Tissue Neoplasms / surgery. Surgical Flaps

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(PMID = 16607749.001).

[ISSN] 0048-7848

[Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i

[ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi

[Language] rum

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Romania

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Severe exacerbation of multiple self-healing squamous epithelioma (Ferguson-Smith disease) with radiotherapy, which was successfully treated with acitretin.

Multiple self-healing squamous epithelioma, otherwise known as Ferguson-Smith disease, was diagnosed.

[MeSH-major] Acitretin / therapeutic use. Carcinoma, Squamous Cell / radiotherapy. Facial Neoplasms / radiotherapy. Keratoacanthoma / radiotherapy. Neoplasms, Multiple Primary / radiotherapy. Skin Neoplasms / radiotherapy

[MeSH-minor] Humans. Keratolytic Agents / therapeutic use. Male. Middle Aged. Neoplasms, Radiation-Induced / drug therapy. Neoplastic Syndromes, Hereditary / drug therapy. Neoplastic Syndromes, Hereditary / pathology. Neoplastic Syndromes, Hereditary / radiotherapy

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(PMID = 19874360.001).

[ISSN] 1365-2230

[Journal-full-title] Clinical and experimental dermatology

[ISO-abbreviation] Clin. Exp. Dermatol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Keratolytic Agents; LCH760E9T7 / Acitretin

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] CNS and lung metastasis of sebaceous epithelioma in a dog.

Sebaceous epithelioma is a common canine cutaneous neoplasm characterized by a preponderance of basaloid cells with few well-differentiated sebocytes.

This case report presents the clinical and pathological features of a sebaceous epithelioma of the upper lip with a highly aggressive behaviour.

The patient was a 9-year-old female dachshund that developed local recurrence 11 months after the excision of the primary sebaceous epithelioma and multiple lung and central nervous system metastases 5 months later.

[MeSH-major] Brain Neoplasms / veterinary. Carcinoma / veterinary. Dog Diseases / pathology. Lung Neoplasms / veterinary. Skin Neoplasms / veterinary

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(PMID = 19552699.001).

[ISSN] 1365-3164

[Journal-full-title] Veterinary dermatology

[ISO-abbreviation] Vet. Dermatol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] A case of verrucous carcinoma (epithelioma cuniculatum) of the heel mimicking infected epidermal cyst and gout.

Verrucous carcinoma of the sole, also called epithelioma cuniculatum, often presents a diagnostic challenge both clinically and histopathologically.

[MeSH-major] Carcinoma, Verrucous / diagnosis. Debridement / methods. Epidermal Cyst / diagnosis. Gout / diagnosis. Skin Neoplasms / diagnosis

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(PMID = 19825731.001).

[ISSN] 1938-7636

[Journal-full-title] Foot & ankle specialist

[ISO-abbreviation] Foot Ankle Spec

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Pilomatricoma or calcifying epithelioma of Malherbe. A pediatric review of 89 cases].

[Transliterated title] Pilomatricome ou épithélioma calcifié de Malherbe : à propos d'une série de 89 cas chez l'enfant.

This tumor, also known as calcifying epithelioma of Malherbe, is common in the pediatric population and occurs mainly on the head and neck region.

It is a benign skin neoplasm usually misdiagnosed and yet the most common hair follicle tumor.

Principal characteristics and clinical presentation of this tumor are discussed.

[MeSH-major] Hair Diseases / pathology. Head and Neck Neoplasms / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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(PMID = 17030388.001).

[ISSN] 0294-1260

[Journal-full-title] Annales de chirurgie plastique et esthétique

[ISO-abbreviation] Ann Chir Plast Esthet

[Language] fre

[Publication-type] English Abstract; Journal Article

[Publication-country] France

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Epithelioma cuniculatum plantare in the region of a skin scar due to mechanical trauma. Insurance law aspects of scar carcinomas].

We herein report a case of a highly differentiated verrucous squamous cell carcinoma of the sole of the left forefoot ("epithelioma" or "carcinoma cuniculatum plantare") that had--as a specific feature--developed within a preexisting long-standing skin scar due to an earlier occupational crush injury.

Because of expansive tumor growth extending to the metatarsal bones and penetrating the tissue between the tendons, an ultrashort amputation of the hindfoot was performed according to the method of Chopart.

[MeSH-major] Accidents, Occupational / legislation & jurisprudence. Carcinoma, Verrucous / etiology. Cicatrix / complications. Foot Diseases / etiology. Foot Injuries / complications. Insurance, Health / legislation & jurisprudence. Skin / injuries. Skin Neoplasms / etiology

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(PMID = 16924443.001).

[ISSN] 0177-5537

[Journal-full-title] Der Unfallchirurg

[ISO-abbreviation] Unfallchirurg

[Language] ger

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Cervical adenoid basal tumors comprised of adenoid basal epithelioma associated with various types of invasive carcinoma: clinicopathologic features, human papillomavirus DNA detection, and P16 expression.

Adenoid basal tumors are uncommon cervical lesions that some pathologists consider invasive carcinomas but others consider "epitheliomas" due to their low-grade histological appearance and rarely documented malignant behavior.

We report the clinicopathologic features of 10 tumors comprised of both typical low-grade adenoid basal tumors (epitheliomas) intimately associated with invasive carcinomas having infiltrative growth, increased cytological atypia and mitotic activity, and various types of differentiation, including adenoid basal/squamous, pure squamous, adenoid cystic, and small cell neuroendocrine.

Tumors were evaluated for the presence of human papillomavirus (HPV) DNA and immunohistochemical p16 expression.

Seven patients diagnosed on excisional or biopsy specimens who underwent hysterectomy had residual tumor in the cervix, ranging from microscopic foci to deeply invasive.

HPV 16 DNA was detected in both the adenoid basal epithelioma and invasive carcinoma components in 9 tumors by in situ hybridization, and HPV 33 was detected by polymerase chain reaction in 1 tumor.

All tumors expressed p16 diffusely.

Adenoid basal tumors are high-risk HPV-related tumors that can be comprised of both a low-grade adenoid basal tumor, which can be designated as epithelioma, and invasive carcinomas of various types.

The invasive component is usually evident in the excisional biopsy specimen, allowing for recognition of a tumor that needs further management.

[MeSH-major] Carcinoma, Basal Cell / classification. Carcinoma, Basal Cell / pathology. Cyclin-Dependent Kinase Inhibitor p16 / metabolism. DNA, Viral / isolation & purification. Uterine Cervical Neoplasms / classification. Uterine Cervical Neoplasms / pathology

[MeSH-minor] Aged. Aged, 80 and over. Cervical Intraepithelial Neoplasia / classification. Cervical Intraepithelial Neoplasia / pathology. Cervical Intraepithelial Neoplasia / virology. Conization. Female. Humans. Immunohistochemistry. In Situ Hybridization. Male. Middle Aged. Papillomaviridae. Papillomavirus Infections / complications. Polymerase Chain Reaction

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(PMID = 15712186.001).

[ISSN] 0046-8177

[Journal-full-title] Human pathology

[ISO-abbreviation] Hum. Pathol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA, Viral

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Adenoid basal epithelioma of the uterine cervix in 21-year-old patient. Report of a case with histologic and immunohistochemical study.

A case of adenoid basal epithelioma (ABE) of the uterine cervix in 21-year-old woman is reported.

The tumor showed typical histologic features of ABE and was associated with CIN3.

In addition, rare tumor cells had surface cilia-appearing structures suggesting tubal differentiation.

Immunohistochemically, the tumor was reactive for p63, CD10, ER, PR, p16 and bcl-2, and negative for CEA.

[MeSH-major] Carcinoma, Basal Cell / pathology. Uterine Cervical Neoplasms / pathology

[MeSH-minor] Adult. Cervical Intraepithelial Neoplasia / pathology. Female. Humans. Immunohistochemistry

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(PMID = 16382992.001).

[ISSN] 1210-7875

[Journal-full-title] Československá patologie

[ISO-abbreviation] Cesk Patol

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Czech Republic

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] The elusive multiple self-healing squamous epithelioma (MSSE) gene: further mapping, analysis of candidates, and loss of heterozygosity.

The MSSE gene predisposes to multiple invasive but self-healing skin tumours (multiple self-healing epitheliomata).

We also report the first molecular analysis of MSSE tumours showing loss of heterozygosity of the MSSE region, with loss of the normal allele, providing the first evidence that MSSE is a tumour suppressor gene.

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(PMID = 16170343.001).

[ISSN] 0950-9232

[Journal-full-title] Oncogene

[ISO-abbreviation] Oncogene

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / DNA Primers

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [From "primitive spleen epithelioma" to Gaucher's disease. Story of a forerunner].

[Transliterated title] De "l'epithélioma primitif de la rate" à la maladie de Gaucher, une thèse visionnaire?

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(PMID = 18228690.001).

[ISSN] 0248-8663

[Journal-full-title] La Revue de medecine interne

[ISO-abbreviation] Rev Med Interne

[Language] FRE

[Publication-type] Biography; English Abstract; Historical Article; Journal Article

[Publication-country] France

[Personal-name-as-subject] Gaucher PC

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Heat shock proteins expression in canine intracutaneous cornifying epithelioma and squamous cell carcinoma.

Heat shock proteins (HSPs) are strongly implicated in the control of cell growth, differentiation and biological behaviour of many human cutaneous neoplasms.

Expression was correlated with the histological degree of keratinocyte differentiation and proliferation, and investigated as to its usefulness in the differential diagnosis of these canine tumours.

Hsp27 expression seems to correlate directly with cellular differentiation; by contrast, the involvement of Hsp72/73 in proliferation and differentiation of tumour cells remains controversial.

The pattern and intensity of immunolabelling of each investigated HSP did not show, however, significant differences between ICE and SCC; therefore, they do not seem to be useful in the differential diagnosis of these two canine tumours.

[MeSH-major] Carcinoma / veterinary. Carcinoma, Squamous Cell / veterinary. Dog Diseases / metabolism. Heat-Shock Proteins / metabolism. Skin Neoplasms / veterinary

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(PMID = 15842541.001).

[ISSN] 0959-4493

[Journal-full-title] Veterinary dermatology

[ISO-abbreviation] Vet. Dermatol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Heat-Shock Proteins

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Basal cell tumor or cutaneous basilar epithelial neoplasm? Rethinking the cytologic diagnosis of basal cell tumors.

The cytologic interpretation was malignant neoplasia with histiocytic inflammation.

Histologically, the tumor was diagnosed as a basal cell epithelioma.

Neoplasms that once were lumped into the broad histologic diagnosis of basal cell tumors have since been split into distinct entities, dependent on evidence of differentiation into epidermis, trichofollicular epithelium, or sweat or sebaceous glands.

Although histologic reclassification has resulted in removal of most of these entities from the original basal cell tumor category, a cytologic diagnosis of basal cell tumor continues to be used to represent the large, heterogeneous group of epidermal, trichofollicular, and adnexal skin tumors with basal cell characteristics.

The case in this report demonstrates the heterogeneity of neoplasms that may be diagnosed cytologically as basal cell tumors and supports the need for cytologic criteria and nomenclature that better reflect potential variation in tissue differentiation.

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(PMID = 17123253.001).

[ISSN] 0275-6382

[Journal-full-title] Veterinary clinical pathology

[ISO-abbreviation] Vet Clin Pathol

[Language] ENG

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

BACKGROUND: Craniopharyngioma is histologically a benign epithelial tumor located in the supersellar cistern that often presents aggressive growth and repeated recurrence.

METHODS: The cohorts consisted of 32 patients with AE and 31 patients with SP tumor.

CONCLUSIONS: Microvascular density and VEGF in craniopharyngioma tissue have no correlation with prognosis of the tumor, which may be explained by the minimal blood circulation in the craniopharyngioma.

Adamantine epithelioma showed more tendency to recur than SP.

[MeSH-major] Craniopharyngioma / blood supply. Craniopharyngioma / metabolism. Neoplasm Recurrence, Local / etiology. Pituitary Neoplasms / blood supply. Pituitary Neoplasms / metabolism. Vascular Endothelial Growth Factor A / metabolism

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(PMID = 16904996.001).

[ISSN] 0090-3019

[Journal-full-title] Surgical neurology

[ISO-abbreviation] Surg Neurol

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Verrucous carcinoma of the foot, also known as epithelioma cuniculatum, usually occurs on the inner aspect of the foot.

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(PMID = 16286378.001).

[ISSN] 1534-7346

[Journal-full-title] The international journal of lower extremity wounds

[ISO-abbreviation] Int J Low Extrem Wounds

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Glucocorticoids; F446C597KA / Triamcinolone Acetonide

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The nomenclature for benign tumors with foci of sebaceous differentiation is confusing and varied.

Furthermore, the unifying architecture of the cases presented supports maintenance of the original nomenclature of superficial epithelioma with sebaceous differentiation and indicates that this neoplasm is perhaps not as rare as currently believed.

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(PMID = 17944728.001).

[ISSN] 0303-6987

[Journal-full-title] Journal of cutaneous pathology

[ISO-abbreviation] J. Cutan. Pathol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Denmark

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

However, no viruses were isolated from diseased or non-diseased specimens using chinook salmon embryo (CHSE-214), flounder fin (FFN) or epithelioma papillosum cyprini (EPC) cell lines.

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(PMID = 19878530.001).

[ISSN] 1365-2761

[Journal-full-title] Journal of fish diseases

[ISO-abbreviation] J. Fish Dis.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

This review covers structural mutations of mitochondrial genes, choosing prostate cancer, esophageal cancer and epithelioma as research models.

[MeSH-major] DNA, Mitochondrial / chemistry. DNA, Mitochondrial / genetics. Electron Transport Chain Complex Proteins / chemistry. Electron Transport Chain Complex Proteins / metabolism. Mutation. Neoplasms / genetics

[MeSH-minor] Animals. Carcinoma / genetics. Esophageal Neoplasms / genetics. Humans. Male. Prostatic Neoplasms / genetics

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(PMID = 18807926.001).

[ISSN] 0032-5422

[Journal-full-title] Postepy biochemii

[ISO-abbreviation] Postepy Biochem.

[Language] pol

[Publication-type] English Abstract; Journal Article; Review

[Publication-country] Poland

[Chemical-registry-number] 0 / DNA, Mitochondrial; 0 / Electron Transport Chain Complex Proteins

[Number-of-references] 53

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Pilomatricoma (calcifying epithelioma of Malherb) is a tumor of hair follicle matrix cells and is almost always benign.

[MeSH-major] Hair Diseases / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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(PMID = 18429799.001).

[ISSN] 1525-1470

[Journal-full-title] Pediatric dermatology

[ISO-abbreviation] Pediatr Dermatol

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Verrucous tumor of the amputation stump].

[Transliterated title] Verruköser Tumor am Amputationsstumpf.

Epithelioma cuniculatum (EC) belongs to the category of verrucous carcinomas.

In cases of long-standing processes with formation of exophytic, malodorous tumors with jagged edges that do not respond to conventional therapy, consideration should already be given to EC upon visual inspection.

The standard treatment of EC is extensive excision of the tumor with micrographic margin control.

[MeSH-major] Amputation Stumps / pathology. Amputation Stumps / surgery. Carcinoma, Verrucous / pathology. Carcinoma, Verrucous / surgery. Skin Neoplasms / pathology. Skin Neoplasms / surgery

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(PMID = 20127299.001).

[ISSN] 1432-1173

[Journal-full-title] Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete

[ISO-abbreviation] Hautarzt

[Language] ger

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Pilomatrixoma also known as calcified epithelioma of Malherbe, is a rare benign cutaneous tumor.

[MeSH-major] Hair Diseases. Pilomatrixoma. Skin Neoplasms

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(PMID = 17175805.001).

[ISSN] 1297-3203

[Journal-full-title] Chirurgie de la main

[ISO-abbreviation] Chir Main

[Language] fre

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] France

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

But it was in 1960, Gorlin-Goltz established the association of basal cell epithelioma, jaw cyst and bifid ribs, a combination which is now frequently known as Gorlin-Goltz syndrome as well as Nevoid Basal Cell Carcinoma Syndrome (NBCCS).

[MeSH-major] Basal Cell Nevus Syndrome / diagnosis. Maxillary Neoplasms / diagnosis

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(PMID = 16900896.001).

[ISSN] 0970-9290

[Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research

[ISO-abbreviation] Indian J Dent Res

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] India

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Sebaceous neoplasms have long been a source of confusion to dermatologists and pathologists alike.

Sebaceous lesions represent a broad spectrum of interesting entities that range from hamartomas, hyperplasias, and benign tumors to highly malignant neoplasms.

This article discusses the clinical and pathologic features of sebaceous hyperplasia, nevus sebaceous of Jadassohn, sebaceous adenoma, seboacanthoma, sebaceous epithelioma, sebaceoma, mantleoma, basal cell carcinoma with sebaceous differentiation, sebomatricoma (sebomatrixoma), and sebaceous carcinoma.

[MeSH-major] Sebaceous Gland Diseases / classification. Sebaceous Gland Diseases / pathology. Sebaceous Gland Neoplasms / classification. Sebaceous Gland Neoplasms / pathology

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(PMID = 19751879.001).

[ISSN] 1097-6787

[Journal-full-title] Journal of the American Academy of Dermatology

[ISO-abbreviation] J. Am. Acad. Dermatol.

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] United States

[Number-of-references] 145

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Pilomatricoma (calcifying epithelioma of Malherbe) is a benign tumor of hair matrix derivation.

[MeSH-major] Biomarkers, Tumor / analysis. Hair Diseases / pathology. Myotonic Dystrophy / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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(PMID = 18718206.001).

[ISSN] 1087-2108

[Journal-full-title] Dermatology online journal

[ISO-abbreviation] Dermatol. Online J.

[Language] eng

[Publication-type] Case Reports; Letter

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Pilomatricoma, also known as "Calcifying Epithelioma of Malherbe" is an uncommon, benign, cutaneous tumor originating from the hair matrix.

[MeSH-major] Facial Neoplasms / diagnosis. Hair Diseases / diagnosis. Pilomatrixoma / diagnosis. Skin Neoplasms / diagnosis

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(PMID = 18797106.001).

[ISSN] 0970-9290

[Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research

[ISO-abbreviation] Indian J Dent Res

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] India

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The occurrence of pilomatricoma (calcifying epithelioma) may be part of the clinical spectrum or a fortuitous finding.

[MeSH-major] Agenesis of Corpus Callosum. Developmental Disabilities / diagnosis. Hair Diseases / diagnosis. Nevus / diagnosis. Pilomatrixoma / diagnosis. Skin Neoplasms / diagnosis. Ventricular Dysfunction, Left / congenital. Ventricular Dysfunction, Left / ultrasonography

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[CommentIn] Am J Med Genet A. 2010 May;152A(5):1328-9; author reply 1330 [20425847.001]

(PMID = 19396836.001).

[ISSN] 1552-4833

[Journal-full-title] American journal of medical genetics. Part A

[ISO-abbreviation] Am. J. Med. Genet. A

[Language] eng

[Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The ΔwaaL mutant was also attenuated in virulence, showed an impaired ability in internalization of epithelioma papulosum cyprinid (EPC) cells and a comparatively poor ability of proliferation in vivo, which was in line with the increased LD(50) value.

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(PMID = 20938646.001).

[ISSN] 1432-072X

[Journal-full-title] Archives of microbiology

[ISO-abbreviation] Arch. Microbiol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Germany

[Chemical-registry-number] 0 / Bacterial Proteins; 0 / DNA, Bacterial; 0 / Lipopolysaccharides; 0 / O Antigens; EC 6.1.- / Carbon-Oxygen Ligases

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

METHOD: Fifty cases with benign hyperplasia at tongue root including tonsillar hypertrophy, lymphangioma and papillary epithelioma were treated with coblation under endoscopy and analyzed retrospectively.

RESULT: All the tumors were resected completely.

[MeSH-major] Catheter Ablation / methods. Tongue Neoplasms / surgery

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(PMID = 19771905.001).

[ISSN] 1001-1781

[Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

[ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

[Language] chi

[Publication-type] English Abstract; Evaluation Studies; Journal Article

[Publication-country] China

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Muir-Torre syndrome is an autosomal-dominant skin condition of genetic origin, characterised by tumours of the sebaceous gland or keratoacanthoma that are associated with visceral malignant diseases.

The cutaneous characteristics of Muir-Torre syndrome are sebaceous adenoma, epithelioma, carcinoma, or multiple keratoacanthomas, whereas visceral malignant diseases include colorectal, endometrial, urological, and upper gastrointestinal tumours.

The most common is a variant of hereditary non-polyposis colorectal cancer, which is characterised by defects in mismatch repair genes and early-onset tumours.

[MeSH-major] DNA Repair. Keratoacanthoma / genetics. Keratoacanthoma / pathology. Sebaceous Gland Neoplasms / genetics. Sebaceous Gland Neoplasms / pathology

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(PMID = 16321766.001).

[ISSN] 1470-2045

[Journal-full-title] The Lancet. Oncology

[ISO-abbreviation] Lancet Oncol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review

[Publication-country] England

[Number-of-references] 66

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The isolated viral strains produced a cytopathic effect on the epithelioma papillosum cyprini cell line.

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(PMID = 17394523.001).

[ISSN] 0140-7775

[Journal-full-title] Journal of fish diseases

[ISO-abbreviation] J. Fish Dis.

[Language] eng

[Databank-accession-numbers] GENBANK/ EF079895/ EF079896/ EF079897/ EF079898/ EF079899

[Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / DNA Primers; 0 / Nucleoproteins

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

A specific cytotoxicity assay has been developed for carp using the Epithelioma Papulosum Cyprini (EPC) cell line as target cells and the release of lactate dehydrogenase (LDH) as read out system.

[MeSH-minor] Animals. Calcium / immunology. Cell Line, Tumor. Egtazic Acid. L-Lactate Dehydrogenase. Membrane Glycoproteins / immunology. Perforin. Pore Forming Cytotoxic Proteins

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(PMID = 15916904.001).

[ISSN] 1050-4648

[Journal-full-title] Fish & shellfish immunology

[ISO-abbreviation] Fish Shellfish Immunol.

[Language] eng

[Publication-type] Comparative Study; Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Membrane Glycoproteins; 0 / Pore Forming Cytotoxic Proteins; 126465-35-8 / Perforin; 526U7A2651 / Egtazic Acid; EC 1.1.1.27 / L-Lactate Dehydrogenase; SY7Q814VUP / Calcium

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Renal epitelial neoplasia associated with Kimura disease.

OBJECTIVE: To present a case of Kimura disease associated with kidney epithelial neoplasia.

Amid the masses and enlarged lymph nodes a nodule suggestive of neoplasm can be found.

There is a case, in the literature that describes Kimura Disease associated with kidney neoplasm.

RESULT: The patient is without signs of Kimura Disease and no signs of recurrence of the tumor after a period of 18 months from surgery.

CONCLUSION: Kimura disease is associated with some neoplasias that should be investigated by the medical team.

[MeSH-major] Angiolymphoid Hyperplasia with Eosinophilia / complications. Kidney Neoplasms / complications

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(PMID = 20876951.001).

[ISSN] 1576-8260

[Journal-full-title] Archivos españoles de urología

[ISO-abbreviation] Arch. Esp. Urol.

[Language] eng; spa

[Publication-type] Case Reports; Journal Article; Review

[Publication-country] Spain

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

A pilomatricoma, or Malherbe's calcifying epithelioma, is an uncommon tumor originating from hair matrix cells.

[MeSH-major] Hair Diseases / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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(PMID = 18715255.001).

[ISSN] 1600-0560

[Journal-full-title] Journal of cutaneous pathology

[ISO-abbreviation] J. Cutan. Pathol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Denmark

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

A pilomatricoma, also known as pilomatrixoma or calcifying epithelioma of Malherbe, is a benign skin tumor arising from the hair follicle matrix.

This tumor is common in children and young adults, especially in the head and neck region.

[MeSH-major] Hair Diseases / diagnosis. Pilomatrixoma / diagnosis. Skin Neoplasms / diagnosis

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(PMID = 20514848.001).

[ISSN] 0001-5458

[Journal-full-title] Acta chirurgica Belgica

[ISO-abbreviation] Acta Chir. Belg.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Belgium

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

In the current study, two different fish cell lines have been used: chinook salmonid embryonic (CHSE-214) cells infected with infectious pancreatic necrosis virus (IPNV) and epithelioma papulosum cyprini (EPC) carp cells infected with infectious hematopoeitic necrosis virus (IHNV).

[MeSH-minor] Animals. Carps. Cell Death / physiology. Cell Line. Cell Line, Tumor. Electric Impedance. Electrodes. Salmonidae. Time Factors

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(PMID = 17826975.001).

[ISSN] 0956-5663

[Journal-full-title] Biosensors & bioelectronics

[ISO-abbreviation] Biosens Bioelectron

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Molecular diagnosis of basal cell carcinoma and other basaloid cell neoplasms of the skin by the quantification of Gli1 transcript levels.

BACKGROUND: Distinguishing basal cell carcinoma (BCC) from other benign and malignant skin tumors is sometimes a difficult task for the pathologists.

METHODS: Gli1 transcript levels were measured by real-time quantitative reverse transcriptase polymerase chain reaction (RT-PCR) using RNA extracted from formalin-fixed, paraffin-embedded tissues of 68 cases of various skin tumors.

RESULTS: The histological diagnoses were unambiguous in 53 tumors.

The tumors included BCC (21), squamous cell carcinoma (13), seborrheic keratoses (8), trichoepithelioma (5), eccrine poroma/porocarcinoma (4), and sebaceous epithelioma/carcinoma (2).

In these unambiguous cases, all BCC and trichoepithelioma tumors showed high expression of Gli1mRNA, while the expression was virtually absent in other tumors.

The diagnosis was discordant among three pathologists in the remaining 15 tumors.

Histological diagnoses included BCC, BCC with sebaceous differentiation, sebaceoma/sebaceous epithelioma, trichoblastoma, trichoepithelioma, basaloid follicular harmartoma, basosquamous carcinoma, etc.

CONCLUSIONS: Quantification of Gli1 transcripts by RT-PCR is helpful in discriminating BCC and trichoepithelioma from other skin tumors.

[MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Basal Cell / diagnosis. Oncogene Proteins / metabolism. Skin Neoplasms / diagnosis. Transcription Factors / metabolism

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(PMID = 15606671.001).

[ISSN] 0303-6987

[Journal-full-title] Journal of cutaneous pathology

[ISO-abbreviation] J. Cutan. Pathol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Denmark

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Gli protein; 0 / Oncogene Proteins; 0 / RNA, Messenger; 0 / Trans-Activators; 0 / Transcription Factors

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The case of a 70-year-old patient with massive squamous cell epithelioma of the vulva complicated by HHM is reported.

[MeSH-major] Carcinoma, Squamous Cell / complications. Hypercalcemia / etiology. Paraneoplastic Syndromes / etiology. Vulvar Neoplasms / complications

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(PMID = 16205603.001).

[ISSN] 0026-4784

[Journal-full-title] Minerva ginecologica

[ISO-abbreviation] Minerva Ginecol

[Language] eng; ita

[Publication-type] Case Reports; Journal Article

[Publication-country] Italy

[Chemical-registry-number] 0 / Parathyroid Hormone-Related Protein

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Transliterated title] Abord ventral transcervicomanubrial du rachis thoracique supérieur: note technique à propos de six cas.

Six patients (24 to 75 years old) were operated on by the same operator (LN) by cervicomanubriotomy from 2002 to 2007 for upper thoracic spinal cord compression (one case of Pott's disease, three cases of metastases, one fracture, one invasive hemangio-epithelioma), with a good outcome in five patients.

[MeSH-minor] Adult. Aged. Decompression, Surgical. Dislocations / surgery. Female. Fracture Fixation. Humans. Male. Middle Aged. Paraplegia / etiology. Spinal Cord Compression / surgery. Spinal Cord Injuries / complications. Spinal Cord Injuries / surgery. Spinal Neoplasms / secondary. Spinal Neoplasms / surgery. Tomography, X-Ray Computed. Tuberculosis, Spinal / surgery

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(PMID = 18343460.001).

[ISSN] 0028-3770

[Journal-full-title] Neuro-Chirurgie

[ISO-abbreviation] Neurochirurgie

[Language] fre

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] France

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

To establish the potential use of cell cultures as a simple and sensitive biological tool to detect environmental pollutants, six cell lines established from several fish species including GCF (grass carp fins), CIK (Ctenopharyngodon idellus kidney), EPC (epithelioma papulosum cyprini), CCO (channel catfish ovary), BB (brown bullhead caudal trunk) and FHM (fathead minnow muscle) were tested and compared for their cytotoxic sensitivity to four heavy metals: cadmium (Cd), chromium (Cr), zinc (Zn), and copper (Cu).

Comparative analysis of these fish cell lines showed that C. idellus kidney (CIK) cells are the most sensitive cell line to copper, epithelioma papulosum cyprini (EPC) cells are more sensitive than other cells to Cr and Zn, while channel catfish ovary (CCO) cell line is the most sensitive one to Cd.

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(PMID = 17931828.001).

[ISSN] 0887-2333

[Journal-full-title] Toxicology in vitro : an international journal published in association with BIBRA

[ISO-abbreviation] Toxicol In Vitro

[Language] eng

[Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / Metals, Heavy; 0 / Water Pollutants, Chemical; 00BH33GNGH / Cadmium; 0R0008Q3JB / Chromium; 789U1901C5 / Copper; J41CSQ7QDS / Zinc

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Biofilm-entrapped LMBV retained infectivity when tested on epithelioma papillosum cyprini tissue culture cells.

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(PMID = 20848884.001).

[ISSN] 0899-7659

[Journal-full-title] Journal of aquatic animal health

[ISO-abbreviation] J. Aquat. Anim. Health

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

PURPOSE: High-dose-rate (192)Ir-based brachytherapy can be used as an exclusive treatment of large skin tumors when teletherapy or surgery is not feasible.

A case of an extended inoperable skin epithelioma of the hand is reported; the lesion involved the first finger, the tenar, the palm, and the back.

Therefore, we conclude that the treatment technique is well adaptable to any particular geometry and that the fractionation scheme has proven to be well tolerated and effective in tumor eradication.

[MeSH-major] Brachytherapy / methods. Carcinoma, Squamous Cell / radiotherapy. Hand / pathology. Skin Neoplasms / radiotherapy

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(PMID = 18599358.001).

[ISSN] 1538-4721

[Journal-full-title] Brachytherapy

[ISO-abbreviation] Brachytherapy

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

2D2, 2D3, and 2F5 partially inhibited SMRV infection in epithelioma papulosum cyprinid (EPC) cell culture.

[MeSH-minor] Animals. Antibody Specificity. Antigens, Viral / isolation & purification. Antigens, Viral / metabolism. Cell Line, Tumor. Cytoplasm / metabolism. Cytoplasm / virology. Flounder / metabolism. Flow Cytometry. Immunoglobulin G / immunology. Immunoglobulin M / immunology. Immunohistochemistry. Mice. Mice, Inbred BALB C. Molecular Weight. Rhabdoviridae Infections / virology. Time Factors. Viral Proteins / chemistry. Viral Proteins / immunology. Viral Proteins / metabolism

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(PMID = 17201659.001).

[ISSN] 0882-8245

[Journal-full-title] Viral immunology

[ISO-abbreviation] Viral Immunol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Viral; 0 / Antigens, Viral; 0 / Immunoglobulin G; 0 / Immunoglobulin M; 0 / Viral Proteins

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The father of the patient also indicated prior surgery to correct an ocular coloboma and prior removal of a squamous cell epithelioma of the tongue.

In patients with SNS the risk of developing neoplasms is higher than that of the general population.

The authors believe that early diagnosis and awareness of the potential presence of neoplasms are important for those involved in the care of patients with SNS.

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(PMID = 19834440.001).

[ISSN] 0392-0488

[Journal-full-title] Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia

[ISO-abbreviation] G Ital Dermatol Venereol

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Italy

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

1) Classified according to system: 41 cases had tumor (29.1%), 25 cases had respiratory diseases (17.7%), 18 cases had infectious diseases (12.7%);.

The top cause of death was respiratory diseases during the former 10 years and was tumor during the latter 10 years; the materials showed that 95 cases were 28 d-3 years old (67.4%), and some rare diseases, such as mediastinal and lung chorionic epithelioma (choriocarcinoma), and pulmonary alveolar proteinosis were found. (3) In 90 cases the clinical diagnosis was basically in accordance with the pathological diagnosis (63.8%) and misdiagnosis was found in 51 cases (36.2%).

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(PMID = 19099750.001).

[ISSN] 0578-1310

[Journal-full-title] Zhonghua er ke za zhi = Chinese journal of pediatrics

[ISO-abbreviation] Zhonghua Er Ke Za Zhi

[Language] chi

[Publication-type] English Abstract; Journal Article

[Publication-country] China

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Cutaneous squamous cell carcinoma (SCC) includes many subtypes with widely varying clinical behaviors, ranging from indolent to aggressive tumors with significant metastatic potential.

However, the tendency for pathologists and clinicians alike is to refer to all squamoid neoplasms as generic SCC.

Intermediate-risk SCCs include adenoid (acantholytic) SCC, intraepidermal epithelioma with invasion, and lymphoepithelioma-like carcinoma of the skin.

High-risk subtypes include de novo SCC, SCC arising in association with predisposing factors (radiation, burn scars, and immunosuppression), invasive Bowen's disease, adenosquamous carcinoma, and malignant proliferating pilar tumors.

Subclassification of SCC into these risk-based categories, along with enumeration of other factors including tumor size, differentiation, depth of invasion, and perineural invasion will provide prognostically relevant information and facilitate the most optimal treatment for patients.

[MeSH-major] Carcinoma, Squamous Cell / classification. Carcinoma, Squamous Cell / pathology. Skin Neoplasms / classification. Skin Neoplasms / pathology

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NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

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(PMID = 16630176.001).

[ISSN] 0303-6987

[Journal-full-title] Journal of cutaneous pathology

[ISO-abbreviation] J. Cutan. Pathol.

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] Denmark

[Number-of-references] 234

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Cutaneous squamous cell carcinoma (SCC) includes many subtypes with widely varying clinical behaviors, ranging from indolent to aggressive tumors with significant metastatic potential.

However, the tendency for pathologists and clinicians alike is to refer to all squamoid neoplasms as generic SCC.

Intermediate-risk SCCs include adenoid (acantholytic) SCC, intraepidermal epithelioma with invasion, and lymphoepithelioma-like carcinoma of the skin.

High-risk subtypes include de novo SCC, SCC arising in association with predisposing factors (radiation, burn scars, and immunosuppression), invasive Bowen's disease, adenosquamous carcinoma, and malignant proliferating pilar tumors.

Subclassification of SCC into these risk-based categories, along with enumeration of other factors including tumor size, differentiation, depth of invasion, and perineural invasion will provide prognostically relevant information and facilitate the most optimal treatment for patients.

[MeSH-major] Carcinoma, Squamous Cell / classification. Carcinoma, Squamous Cell / pathology. Skin Neoplasms / classification. Skin Neoplasms / pathology

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(PMID = 16466506.001).

[ISSN] 0303-6987

[Journal-full-title] Journal of cutaneous pathology

[ISO-abbreviation] J. Cutan. Pathol.

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] Denmark

[Number-of-references] 234

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

BACKGROUND: A cholesteatoma, also known as an epithelioma, is a mass of soft tissue that results from the accumulation of keratin protein debris enclosed by a layer of stratified squamous epithelium.

Because of its location, mass effect, and potential stenosis of the internal carotids, this slow-growing tumor is potentially sight threatening.

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[Copyright] Copyright (c) 2010 American Optometric Association. Published by Elsevier Inc. All rights reserved.

(PMID = 20211442.001).

[ISSN] 1558-1527

[Journal-full-title] Optometry (St. Louis, Mo.)

[ISO-abbreviation] Optometry

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

A new tool for DNA transfer to fish cell lines such as epithelioma papulosum cyprini (EPC) and rainbow trout gonad (RTG2), has been optimized by testing commercially available polyethylenimine (PEI) polymers as transfectant reagents.

[MeSH-minor] Animals. Cell Line, Tumor. Gene Expression Regulation. Molecular Weight

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(PMID = 19250970.001).

[ISSN] 1095-9947

[Journal-full-title] Fish & shellfish immunology

[ISO-abbreviation] Fish Shellfish Immunol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 9002-98-6 / Polyethyleneimine

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Verrucous carcinoma (VC), also known as epithelioma cuniculatum, of the foot is an uncommon low-grade squamous cell carcinoma with slow, progressive local invasion with minimal dysplasia and low potential for metastasis.

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(PMID = 19183994.001).

[ISSN] 0364-2348

[Journal-full-title] Skeletal radiology

[ISO-abbreviation] Skeletal Radiol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Adhesion and invasion abilities of the mutant strain on epithelioma papillosum of carp cells was only 56% of that of the wild-type strain, and the cytotoxicity of the mutant strain to epithelioma papillosum of carp cells was only 42% of that of the wild-type strain.

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(PMID = 18388966.001).

[ISSN] 0008-4166

[Journal-full-title] Canadian journal of microbiology

[ISO-abbreviation] Can. J. Microbiol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Canada

[Chemical-registry-number] 0 / Bacterial Proteins; 0 / Virulence Factors; EC 3.4.24.- / Collagenases

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Muir-Torre syndrome (MTS) is an autosomal, dominantly inherited disorder characterized by sebaceous neoplasms and visceral malignancies.

We report a 56-year-old woman who underwent resections of extraocular sebaceous carcinoma, sebaceous epithelioma, actinic keratosis, and keratoacanthoma (KA)-like squamous cell carcinoma (SCC) with venous invasion metachronously over a 9-year period.

This patient presented with intriguing squamous lesions including keratoacanthoma-like squamous cell carcinoma that showed venous invasion and actinic keratosis, and associated loss of hMSH2 expression, in addition to the sebaceous neoplasms typical of Muir-Torre syndrome.

[MeSH-major] Adenocarcinoma, Sebaceous / pathology. Sebaceous Gland Neoplasms / pathology. Syndrome

[MeSH-minor] Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / pathology. Cell Nucleus / metabolism. Cell Nucleus / pathology. Female. Humans. Immunohistochemistry. Keratoacanthoma / genetics. Keratoacanthoma / metabolism. Keratoacanthoma / pathology. Loss of Heterozygosity. Middle Aged. MutS Homolog 2 Protein / genetics. MutS Homolog 2 Protein / metabolism

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(PMID = 16456327.001).

[ISSN] 0193-1091

[Journal-full-title] The American Journal of dermatopathology

[ISO-abbreviation] Am J Dermatopathol

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.6.1.3 / MSH2 protein, human; EC 3.6.1.3 / MutS Homolog 2 Protein

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Although the lesion on the frontal scalp also showed sebaceous differentiation, there were a greater number of basaloid cells, some with hyperchromatic nuclei and mitotic figures; this was consistent with a diagnosis of sebaceous epithelioma (Fig. 2).

No further treatment was required for these benign sebaceous tumors, but their presence defined our patient's condition as Muir-Torre syndrome.

Mohs' micrographic surgery was performed on the tragus BCC and the margins were tumor free in one stage.

Histologically, this lesion was also consistent with sebaceous epithelioma.

[MeSH-major] Breast Neoplasms / complications. Carcinoma, Basal Cell / complications. Colonic Neoplasms / complications. Skin Neoplasms / complications. Uterine Cervical Neoplasms / complications

[MeSH-minor] Adenoma / complications. Adenoma / genetics. Aged. Carcinoma / complications. Carcinoma / genetics. Female. Genetic Diseases, Inborn / genetics. Humans. Sebaceous Gland Neoplasms / complications. Sebaceous Gland Neoplasms / genetics. Syndrome

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(PMID = 16533237.001).

[ISSN] 0011-9059

[Journal-full-title] International journal of dermatology

[ISO-abbreviation] Int. J. Dermatol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Tumors originating from the lacrimal sac are exceedingly rare.

They may mimic chronic inflammation and be misdiagnosed, delaying treatment and allowing the tumor to devastate the visual system.

Consequently, an external dacryocystorhinostomy was performed, during which an open biopsy specimen was taken; it suggested the presence of a basocellular epithelioma.

On this basis, the patient underwent preoperative radiation (41.4 Gy) and conservative surgical resection of the tumor, with preservation of the eye and extraocular muscles.

This report highlights the clinicopathologic characteristics and therapeutic uncertainty of this rare tumor.

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(PMID = 20485052.001).

[ISSN] 1536-3732

[Journal-full-title] The Journal of craniofacial surgery

[ISO-abbreviation] J Craniofac Surg

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Expression of the claudin-4 molecule in benign and malignant canine hepatoid gland tumours.

Claudins are integral membrane proteins of the tight junction structures expressed by epithelial and endothelial cells.

Claudin-4 was detected as a well-localised linear circumferential membranous staining pattern of epithelial cells (mature hepatoid cells) in normal hepatoid glands, perianal gland hyperplasias and adenomas.

These results suggest that low claudin-4 expression in epitheliomas is a molecular characteristic indicative of increasing cellular disorientation, detachment motility and invasion by tumour cells, and claudin-4 seems to be helpful in distinguishing undifferentiated carcinomas from differentiated carcinomas and epitheliomas of the hepatoid gland.

In addition, claudin-4 can help distinguish epithelioma from differentiated carcinoma of the canine hepatoid gland.

[MeSH-major] Anal Gland Neoplasms / metabolism. Dog Diseases / metabolism. Gene Expression Regulation, Neoplastic / physiology. Membrane Proteins / metabolism

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(PMID = 19897451.001).

[ISSN] 0236-6290

[Journal-full-title] Acta veterinaria Hungarica

[ISO-abbreviation] Acta Vet. Hung.

[Language] eng

[Publication-type] Journal Article

[Publication-country] Hungary

[Chemical-registry-number] 0 / Claudin-4; 0 / Membrane Proteins

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Although there were no obvious differences between the wild-type and the rpoS mutant in adherence of epithelioma papulosum cyprini (EPC) cell and in the lethality on fish model, rpoS deletion leads to the drastically reduced capacity for E. tarda to internalize in EPC cells, indicating that RpoS was, while not the main, the factor required for the virulence network of E. tarda.

[MeSH-minor] Animals. Bacterial Adhesion. Enterobacteriaceae Infections / microbiology. Epithelial Cells / microbiology. Fish Diseases / microbiology. Flatfishes / microbiology. Gene Deletion. Genetic Complementation Test. Microbial Viability. Oxidative Stress. Serum / microbiology. Virulence

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(PMID = 19283379.001).

[ISSN] 1432-0614

[Journal-full-title] Applied microbiology and biotechnology

[ISO-abbreviation] Appl. Microbiol. Biotechnol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Germany

[Chemical-registry-number] 0 / Bacterial Proteins; 0 / Sigma Factor; 0 / sigma factor KatF protein, Bacteria; EC 4.2.2.- / Chondroitinases and Chondroitin Lyases

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

We applied real time quantitative PCR (RQ-PCR) to measure the expression of the pro-inflammatory cytokines CXCa, CXCb, interleukin (IL)1-beta, tumor necrosis factor alpha (TNFalpha), and the receptors IL1R1, CXCR1 and CXCR2 in skin of Cyprinus carpio after mechanical injury.

In order to correlate gene expression patterns after injury with cell migration, we studied chemotaxis of head kidney leukocytes towards lysates of epithelioma papulosum cyprini (EPC) cells.

Neutrophilic granulocytes were shown to migrate towards epithelial lysates.

[MeSH-minor] Animals. Granulocytes / immunology. Interleukin-1beta. Receptors, Chemokine. Receptors, Interleukin-1 Type I. Skin / immunology. Skin / injuries. Tumor Necrosis Factor-alpha. Up-Regulation

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(PMID = 17034853.001).

[ISSN] 0145-305X

[Journal-full-title] Developmental and comparative immunology

[ISO-abbreviation] Dev. Comp. Immunol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Chemokines, CXC; 0 / Interleukin-1beta; 0 / Receptors, Chemokine; 0 / Receptors, Interleukin-1 Type I; 0 / Tumor Necrosis Factor-alpha

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Isolates of VHSV representing the geographic range of North American VHSV replicated in the EPC (Epithelioma papulosum cyprini) cell line at 10, 15 and 20 degrees C, but the more northern isolates from British Columbia, Canada, demonstrated significantly reduced growth at 20 degrees C compared to VHSV from more southern locations (p <0.001).

[MeSH-minor] Animals. Cell Line, Tumor. Culture Media / analysis. Fishes. Freezing. Kidney / virology. North America. Spleen / virology. Survival Analysis. Temperature. Virus Replication / physiology

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(PMID = 16724558.001).

[ISSN] 0177-5103

[Journal-full-title] Diseases of aquatic organisms

[ISO-abbreviation] Dis. Aquat. Org.

[Language] eng

[Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

[Publication-country] Germany

[Chemical-registry-number] 0 / Culture Media

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The results indicate that rDreIFN has higher activity against SVCV and IHNV on epithelioma papulosum cyprinid (EPC) than on grass carp (C. idellus) ovary (CO) cell lines and no activity against VSV on chick embryo fibroblasts (CEF).

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(PMID = 16704302.001).

[ISSN] 1079-9907

[Journal-full-title] Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research

[ISO-abbreviation] J. Interferon Cytokine Res.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Interferon Type I; 0 / Recombinant Proteins; 0 / Zebrafish Proteins

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

We describe the pathology, isolation and characterisation of a virus responsible for an outbreak of a systemic haemorrhagic disease causing high mortality in tadpoles of the common midwife toad Alytes obstetricans in the 'Picos de Europa' National Park in northern Spain.

The virus, provisionally designated as the common midwife toad virus (CMTV), was isolated from homogenates of visceral tissue from diseased toad tadpoles following inoculation on epithelioma papulosum cyprini (EPC) cells.

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(PMID = 19476279.001).

[ISSN] 0177-5103

[Journal-full-title] Diseases of aquatic organisms

[ISO-abbreviation] Dis. Aquat. Org.

[Language] eng

[Publication-type] Journal Article

[Publication-country] Germany

[Chemical-registry-number] 0 / Viral Proteins

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Joseph Babinski (1857-1932), a French neurologist of Polish origin, médecin des hôpitaux de Paris, is well known for the discovery of the Sign (the toes phenomenon) which bears his name.

However, in the beginning of his career, Babinski worked as an Interne in the clinical departments of Victor Cornil (1837-1908), professor of pathological anatomy and president of the Société d'Anatomie de Paris, Alfred Vulpian (1826-1887), past professor of pathological anatomy and then professor of experimental physiology, and in the laboratory of Louis Ranvier (1835-1922), professor of general anatomy at the Collège de France.

Babinski beacame préparateur at the chair of pathological anatomy, member then treasurer of the Société Anatomique, member of the Société de Biologie.

He reported on several clinico-pathological observations of general pathology (liver cirrhosis, cancer of the kidney, cancer of a buttock, squamous epithelioma, tuberculosis, multiple cysts of the liver and the kidneys, bowel occlusion), of neuropathology (embolic brain softenings, hydatic cysts of the brain, multiple sclerosis, spinal cord combined sclerosis, tabetic arthropathies, adiposo-genital syndrome due to a pituitary tumor) and of human neuro-muscular histology (neuro-muscular spindles, muscular histology after nerve sectioning, diphtheria paralysis, peripheral neuritis).

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(PMID = 18516338.001).

[ISSN] 1220-0522

[Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

[ISO-abbreviation] Rom J Morphol Embryol

[Language] eng

[Publication-type] Biography; Historical Article; Journal Article

[Publication-country] Romania

[Personal-name-as-subject] Babinski J

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The skin culture fluid produced staining signals in viral assembly sites and cytoplasm of SMRV-infected epithelioma papulosum cyprini (EPC) cells by IFA.

[MeSH-minor] Animals. Blotting, Western. Cell Line. Cell Line, Tumor. Culture Media. Enzyme-Linked Immunosorbent Assay. Flow Cytometry. Fluorescent Antibody Technique, Indirect. Viral Proteins / metabolism. Viral Vaccines / immunology

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(PMID = 18482386.001).

[ISSN] 1365-2761

[Journal-full-title] Journal of fish diseases

[ISO-abbreviation] J. Fish Dis.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / Antibodies, Viral; 0 / Culture Media; 0 / Viral Proteins; 0 / Viral Vaccines

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

In this paper, we assess the antiproliferative activity of probiotics in two teleost fish cell lines SAF-1, a fibroblast cell line and EPC, an epithelioma from carp.

[MeSH-minor] Animals. Cell Line. Cell Proliferation / drug effects. Epithelial Cells / cytology. Epithelial Cells / drug effects. Fibroblasts / cytology. Fibroblasts / drug effects. Time Factors

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(PMID = 17706899.001).

[ISSN] 0378-1135

[Journal-full-title] Veterinary microbiology

[ISO-abbreviation] Vet. Microbiol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Netherlands

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Interestingly, the epithelioma papulosum Cyprini cells derived from Cyprinus carpio are restrictive to the virus.

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(PMID = 17497237.001).

[ISSN] 0304-8608

[Journal-full-title] Archives of virology

[ISO-abbreviation] Arch. Virol.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Austria

[Chemical-registry-number] 0 / Viral Proteins

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Pilomatricoma, also known as 'calcifying epithelioma of Malherbe', is a common skin adnexal tumor that mimics hair growth.

This aberration was corroborated by interphase fluorescence in situ hybridization, using a chromosome 18 pericentromeric probe, in the basaloid epithelial component of 7 of 11 pilomatricomas, including the index case.

Trisomy 18 was present in a small subset of cells, suggesting a role in pilomatricoma progression, rather than in tumor initiation.

We conclude that trisomy 18 is a consistent feature in pilomatricoma, suggesting that genes carried on this chromosome, such as that for the antiapoptotic oncoprotein BCL2, may have a role in the growth and differentiation of this benign self-limited tumor.

[MeSH-major] Chromosomes, Human, Pair 18. Hair Diseases / genetics. Pilomatrixoma / genetics. Skin Neoplasms / genetics. Trisomy

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(PMID = 20495544.001).

[ISSN] 1530-0285

[Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

[ISO-abbreviation] Mod. Pathol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Cutaneous sebaceous neoplasms as markers of Muir-Torre syndrome: a diagnostic algorithm.

Sebaceous gland neoplasms such as adenoma, epithelioma, and carcinoma are uncommon cutaneous tumors.

MTS is a rare autosomal dominant genodermatosis characterized by the occurrence of sebaceous gland neoplasms and/or keratoacanthomas associated with visceral malignancies that include gastrointestinal and genitourinary cancers.

Recent evidence suggests that immunohistochemistry is very sensitive and effective in detecting these defects in cutaneous tumors in MTS.

In addition, the genetic instability of cutaneous and visceral tumors in MTS caused by the defects in MMR genes can also be detected, using polymerase chain reaction (PCR)-based techniques, for microsatellite instability (MSI).

Given that some sebaceous neoplasms represent cutaneous markers of MTS, what should we as dermatopathologists be advocating?

Should we be looking for absence/loss of MMRs in all sebaceous neoplasms?

This review attempts to address all of these issues with a view to streamlining the work-up of a patient presenting for the first time with a sebaceous neoplasm and no prior personal or family history of internal malignancies.

[MeSH-major] Algorithms. Biomarkers, Tumor / genetics. Muir-Torre Syndrome / diagnosis. Sebaceous Gland Neoplasms / diagnosis. Skin Neoplasms / diagnosis

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(PMID = 19515040.001).

[ISSN] 1600-0560

[Journal-full-title] Journal of cutaneous pathology

[ISO-abbreviation] J. Cutan. Pathol.

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] Denmark

[Chemical-registry-number] 0 / Biomarkers, Tumor

[Number-of-references] 36

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Tumours of the bony face in children the treated at the Paediatric ENT Clinic in Warsaw].

INTRODUCTION: The tumours of bony face at in children are rare.

Among the most commonly found are inflammatory tumours and development anomalies.

In inflammatory tumours there are abscess and inflammatory infiltration.

Malignants tumours in this area are rare in children, but are mainly sarcomata or melanoma.

Developmental tumours include cyst and fistula.

OBJECTIVE: To analyse tumours of the bony face treated in Paediatric ENT Clinic in Warsaw.

MATERIAL: There were thirty cases of bony face tumours treated in Paediatric ENT Clinic in Warsaw between 2005 and 2007.

Twenty-one cases (70%) were found to be developmental tumours, three cases (10%) of abscesses, and four cases (13%) of benign tumours.

CONCLUSIONS: The most frequently-found tumours of bony face in children are developmental tumours.

All tumours must be the subject of histopatological examination.

In the case of cancers tumours it has to be established if the tumour is a primary or a metastatic.

In the group analysed group the rare tumour were epithelioma, ganglioma.

[MeSH-major] Facial Bones. Skull Neoplasms / epidemiology. Skull Neoplasms / therapy

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(PMID = 18837212.001).

[ISSN] 0030-6657

[Journal-full-title] Otolaryngologia polska = The Polish otolaryngology

[ISO-abbreviation] Otolaryngol Pol

[Language] pol

[Publication-type] English Abstract; Journal Article

[Publication-country] Poland

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

BACKGROUND: Pilomatrixoma (pilomatrixoma, calcifying epithelioma of Malherbe) is a relatively uncommon, benign neoplasm arising from the skin adnexa.

The tumor can cause diagnostic difficulty not only for the clinician but also for the cytologist.

Three preliminary differential diagnoses were offered: mucoepidermoid carcinoma of the submandibular salivary gland, squamous cell carcinomatous deposit in a submandibular lymph node and calcifying odontogenic tumor.

CONCLUSION: The cytologic presentation of pilomatrixoma of the right submandibular region can masquerade as that of a malignant tumor, in this case mucoepidermoid carcinoma, squamous cell carcinoma or odontogenic tumor.

[MeSH-major] Hair Diseases / diagnosis. Hair Diseases / pathology. Pilomatrixoma / diagnosis. Pilomatrixoma / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / pathology

[MeSH-minor] Biopsy, Fine-Needle. Cell Nucleus / pathology. Epithelial Cells / pathology. Female. Humans. Middle Aged

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(PMID = 17718128.001).

[ISSN] 0001-5547

[Journal-full-title] Acta cytologica

[ISO-abbreviation] Acta Cytol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The viral pathogen was initially cultured and isolated on the epithelioma papulosum cyprini cell line and subsequently shown to produce CPE in the fathead minnow and bluegill fin cell lines.

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(PMID = 17958610.001).

[ISSN] 0140-7775

[Journal-full-title] Journal of fish diseases

[ISO-abbreviation] J. Fish Dis.

[Language] eng

[Databank-accession-numbers] GENBANK/ EF194065

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / Glycoproteins; 0 / RNA, Viral

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Differential diagnosis of neck tumours puts precedence on diagnosing neoplastic lesions.

In the case of neck tumours, these are unfortunately late signs, but in patients with a primary neoplastic focus within the head and neck, neck tumour is often the first sign of the disease.

The authors describe a clinical case of neck tumour with initially unclear etiology.

The preoperative diagnostics including ultrasonography, thin-needle puncture, MRI, carotid angiography and videostroboscopy was significant for surgical treatment planning; yet it was the intraoperative clinical picture which indicated that the tumour derived from the inferior parotid pole.

The histopathological examination confirmed non-cornifying basal cell epithelioma only in the essential lesion with no metastases to lymph nodes and surrounding tissue margins free of infiltrates.

Two and a half years after the procedure, the patient presented with a tumour localized on the front thoracic wall and two rapidly enlarging tumours in the nape of the neck.

In the collected specimen of the tumour on the front thoracic wall, a diagnosis of acinic cell carcinoma was made.

[MeSH-major] Carcinoma, Acinar Cell / pathology. Carcinoma, Acinar Cell / surgery. Parotid Neoplasms / pathology. Parotid Neoplasms / surgery

[MeSH-minor] Aged. Head and Neck Neoplasms / secondary. Humans. Male. Neck Dissection / methods. Neoplasm Staging. Palliative Care. Prognosis. Thoracic Wall / pathology

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(PMID = 20169911.001).

[ISSN] 0030-6657

[Journal-full-title] Otolaryngologia polska = The Polish otolaryngology

[ISO-abbreviation] Otolaryngol Pol

[Language] pol

[Publication-type] English Abstract; Journal Article

[Publication-country] Poland

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Neoplasms of the perianal glands are common in the dog, particularly in the male.

The occurrence of these tumours appears to be hormone related and castration, without excision of the tumour, has sometimes resulted in regression of the tumour.

The lesions, classified according to WHO criteria, were comprised of 19 hyperplastic tissues, 10 benign lesions (2 hepatoid gland epithelioma and 8 hepatoid adenomas), and 19 carcinomas.

In hepatoid carcinomas the percent of AR-positive cells was similar to that observed in benign tumours.

[MeSH-major] Anal Gland Neoplasms / metabolism. Dog Diseases / metabolism. Receptors, Androgen / biosynthesis

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(PMID = 16427103.001).

[ISSN] 0034-5288

[Journal-full-title] Research in veterinary science

[ISO-abbreviation] Res. Vet. Sci.

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Receptors, Androgen

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Immunolabeling pattern of cytokeratin 19 expression may distinguish sebaceous tumors from basal cell carcinomas.

BACKGROUND: Distinction between sebaceous tumors and basal cell carcinomas can often pose diagnostic problems.

Our aim was to evaluate the use of CK 19 staining patterns in differentiating between sebaceous tumors and basal cell carcinomas.

The sebaceous tumors that were examined in this study included sebaceous adenomas, sebaceous epitheliomas (sebaceomas) and sebaceous carcinomas.

Strongly positive expression of CK 19 was not seen in any of the sebaceous adenoma, sebaceous epithelioma or sebaceous carcinoma specimens.

CONCLUSION: CK 19 expression can be helpful in differentiating sebaceous tumors (including sebaceous adenomas, sebaceous epitheliomas and sebaceous carcinomas) from basal cell carcinomas and may be a useful adjunct when these entities are included in the differential diagnosis.

[MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Adenoma / diagnosis. Biomarkers, Tumor / analysis. Carcinoma, Basal Cell / diagnosis. Keratin-19 / analysis. Sebaceous Gland Neoplasms / diagnosis. Sebaceous Glands / pathology

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(PMID = 18095993.001).

[ISSN] 1600-0560

[Journal-full-title] Journal of cutaneous pathology

[ISO-abbreviation] J. Cutan. Pathol.

[Language] eng

[Publication-type] Evaluation Studies; Journal Article

[Publication-country] Denmark

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-19

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Using ranavirus-infected epithelioma papillosum cyprini (EPC) cell cultures, the specificity of the PAb was determined by Western blot, immunogold electron microscopy, and direct enzyme-linked immunosorbent assay (ELISA).

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(PMID = 20481086.001).

[ISSN] 0177-5103

[Journal-full-title] Diseases of aquatic organisms

[ISO-abbreviation] Dis. Aquat. Org.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Germany

[Chemical-registry-number] 0 / Antibodies, Viral