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1. Lesma E, Grande V, Ancona S, Carelli S, Di Giulio AM, Gorio A: Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM. PLoS One; 2008;3(10):e3558
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  • BACKGROUND: Tuberous sclerosis complex (TSC), a tumor syndrome caused by mutations in TSC1 or TSC2 genes, is characterized by the development of hamartomas.


2. Eskelin S, Tommila P, Palosaari T, Kivelä T: Photodynamic therapy with verteporfin to induce regression of aggressive retinal astrocytomas. Acta Ophthalmol; 2008 Nov;86(7):794-9
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  • RESULTS: The progressing, vascularized part of both retinal astrocytomas regressed, with little change in the poorly vascularized, stationary part of the congenital hamartoma.
  • [MeSH-minor] Adult. Aged. Disease Progression. Humans. Light Coagulation. Male. Neoplasm Invasiveness. Prospective Studies. Retinal Detachment / etiology. Treatment Outcome. Tuberous Sclerosis / complications

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  • (PMID = 18759802.001).
  • [ISSN] 1755-3768
  • [Journal-full-title] Acta ophthalmologica
  • [ISO-abbreviation] Acta Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Porphyrins; 129497-78-5 / verteporfin
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3. Khonsari RH, Lepourry J, Corre P: [Hamartomatous and pluritissular tumors]. Rev Stomatol Chir Maxillofac; 2009 Dec;110(6):340-6
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  • [Title] [Hamartomatous and pluritissular tumors].
  • Hamartoma are defined by the benign proliferation of cells normally occurring in the affected tissue or organ.
  • Hamartoma of the maxilla and mandible are a heterogeneous group of diseases.
  • [MeSH-major] Hamartoma / diagnosis. Jaw Diseases / diagnosis. Jaw Neoplasms / diagnosis

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  • (PMID = 19931105.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 20
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4. Rosner M, Freilinger A, Hengstschläger M: The tuberous sclerosis genes and regulation of the cyclin-dependent kinase inhibitor p27. Mutat Res; 2006 Sep;613(1):10-6
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  • It is characterized by the development of tumors, named hamartomas, in the kidneys, heart, skin and brain.
  • This disease is caused by mutations within the tumor suppressor gene TSC1 on chromosome 9q34 encoding hamartin or within TSC2 on chromosome 16p13.3 encoding tuberin.
  • Recent data suggest that functional inactivation of TSC proteins might also be involved in the development of other diseases not associated with TSC, such as sporadic bladder cancer, breast cancer, ovarian carcinoma, gall bladder carcinoma, non-small-cell carcinoma of the lung, and Alzheimer's disease.

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  • (PMID = 16713332.001).
  • [ISSN] 0027-5107
  • [Journal-full-title] Mutation research
  • [ISO-abbreviation] Mutat. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 147604-94-2 / Cyclin-Dependent Kinase Inhibitor p27; 4JG2LF96VF / tuberous sclerosis complex 2 protein
  • [Number-of-references] 67
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5. Odaka A, Takahashi S, Tanimizu T, Kawashima H, Inokuma S, Ishida H, Hoshino T, Baba K, Tamura M, Satomi A, Hashimoto D: Chest wall mesenchymal hamartoma associated with a massive fetal pleural effusion: a case report. J Pediatr Surg; 2005 May;40(5):e5-7
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  • [Title] Chest wall mesenchymal hamartoma associated with a massive fetal pleural effusion: a case report.
  • Abstract We report on an extremely rare chest wall mesenchymal hamartoma associated with a massive fetal pleural effusion.
  • Histological examination confirmed the diagnosis of a chest wall mesenchymal hamartoma.
  • [MeSH-major] Fetal Diseases / etiology. Hamartoma / surgery. Infant, Premature, Diseases / surgery. Pleural Effusion / etiology. Thoracic Diseases / surgery. Thoracic Wall


6. Delman BN, Fatterpekar GM, Law M, Naidich TP: Neuroimaging for the pediatric endocrinologist. Pediatr Endocrinol Rev; 2008 Feb;5 Suppl 2:708-19
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  • Cystic lesions such as Rathke's cleft cysts are commonly seen in the gland, even in healthy children, and their presence need not correlate with any functional abnormality; however, such cysts can cause mass effect on the remaining gland, reflect hemorrhage into adenoma, or actually comprise the central portion of a more worrisome tumor such as craniopharyngioma.
  • Solid tumors of the suprasellar region include optic pathway gliomas, hamartomas, and germinomas.


7. Darling TN: Hitting the mark in hamartoma syndromes. Adv Dermatol; 2006;22:181-200
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  • [Title] Hitting the mark in hamartoma syndromes.
  • The missed mark or hamartia underlying each hamartoma syndrome is a mutation in a tumor suppressor gene.
  • [MeSH-major] Hamartoma Syndrome, Multiple

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  • (PMID = 17249302.001).
  • [ISSN] 0882-0880
  • [Journal-full-title] Advances in dermatology
  • [ISO-abbreviation] Adv Dermatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 109
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8. Petersen JM, Felger TS, Goldstein JD: Gastroduodenal intussusception secondary to a giant brunner gland hamartoma. Gastroenterol Hepatol (N Y); 2008 Jul;4(7):471-3
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  • [Title] Gastroduodenal intussusception secondary to a giant brunner gland hamartoma.

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  • [Cites] Gastroenterol Jpn. 1993 Feb;28(1):118-25 [8382639.001]
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  • (PMID = 21960921.001).
  • [ISSN] 1554-7914
  • [Journal-full-title] Gastroenterology & hepatology
  • [ISO-abbreviation] Gastroenterol Hepatol (N Y)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3096128
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9. Mayo SC, Huang H, Dobos N, Billingsley KG: Image of the month. Retrorectal cystic hamartoma (tailgut cyst). Arch Surg; 2008 Oct;143(10):1017, 1018
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  • [Title] Image of the month. Retrorectal cystic hamartoma (tailgut cyst).
  • [MeSH-major] Adenocarcinoma / pathology. Cell Transformation, Neoplastic / pathology. Cysts / pathology. Hamartoma / pathology. Magnetic Resonance Imaging

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  • (PMID = 18936384.001).
  • [ISSN] 1538-3644
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Mezoff A, Prued'Homme D, Hodges C, Milliken T, Michail S: Capsule endoscopy in pediatric patients with hamartomatous polyp syndromes. J Pediatr Gastroenterol Nutr; 2006 Feb;42(2):240-2
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  • [Title] Capsule endoscopy in pediatric patients with hamartomatous polyp syndromes.

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  • (PMID = 16456423.001).
  • [ISSN] 0277-2116
  • [Journal-full-title] Journal of pediatric gastroenterology and nutrition
  • [ISO-abbreviation] J. Pediatr. Gastroenterol. Nutr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Capsules
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11. Scheper MA, Nikitakis NG, Sarlani E, Sauk JJ, Meiller TF: Cowden syndrome: report of a case with immunohistochemical analysis and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 May;101(5):625-31
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  • Cowden syndrome is a rare condition defined by multiple hamartomatous growths and a guarded prognosis owing to the high risk of cancer development.
  • Presented here is a case of Cowden syndrome in a patient with multiple hamartomas of the nose, midfacial skin and oral mucosa, and fissured tongue; plus a history of bipolar disease, iron deficiency anemia, basal cell carcinoma, fibroids of the uterus, and arthritis.
  • [MeSH-major] Hamartoma Syndrome, Multiple / pathology. Mouth Mucosa / pathology. Skin Diseases / pathology. Tongue Diseases / pathology

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  • (PMID = 16632275.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
  • [Number-of-references] 41
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12. Rasalkar DD, Paunipagar BK: Testicular hamartomas and epididymal tumor in a cowden disease: a case report. Case Rep Med; 2010;2010:135029
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  • [Title] Testicular hamartomas and epididymal tumor in a cowden disease: a case report.
  • Testicular hamartomas (TH) is a benign condition.
  • An association of TH with Cowden disease (CD) is known.
  • Ultrasound features of hamartomas are often diagnostic.
  • We present a case of Cowden disease with TH and an epididymal tumor.
  • Although, association of Cowden disease with many malignancies have been documented, epididymal tumor has not been described.
  • To our knowledge, this paper is the first to describe epididymal tumor in association with Cowden disease.

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  • [Cites] Pathol Annu. 1990;25 Pt 2:51-108 [2202966.001]
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  • (PMID = 20589082.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2892650
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13. Voykov B, Guenova E, Süsskind D, Schiefer U: [Tuberous sclerosis: an interdisciplinary diagnosis]. Klin Monbl Augenheilkd; 2007 May;224(5):441-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Tuberous sclerosis is a relatively rare disease, but it often takes a progressive and severe course.
  • We observed an elevated, multinodular, opaque hamartoma resembling mulberries, approximately (1/3)-(1/2) PD large, at the temporal superior arc with corresponding visual field defects.
  • CONCLUSIONS: An ophthalmologist should always think of a tuberous sclerosis as a differential diagnosis when confronted with a retinal hamartoma.
  • [MeSH-major] Hamartoma Syndrome, Multiple / diagnosis. Patient Care Team. Retinal Diseases / diagnosis. Tuberous Sclerosis / diagnosis


14. Podralska M, Nowakowska D, Steffen J, Cichy W, Slomski R, Plawski A: First Polish Cowden syndrome patient with confirmed PTEN gene mutation. Arch Med Sci; 2010 Mar 1;6(1):135-7
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  • Cowden syndrome is a rare hereditary disease.
  • Incidence of the disease is conditioned by occurrence of mutations in the PTEN gene.
  • The disease has a frequency of 1/120,000 newborn and it predisposes to the occurrence of hamartoma polyps in the gastrointestinal tract, skin tumours, as well as tumours of the breast, ovary and thyroid.
  • The disease course of the patient is described and discussed along with other cases of carriers of substitution 68T>A in the PTEN gene.

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  • (PMID = 22371735.001).
  • [ISSN] 1896-9151
  • [Journal-full-title] Archives of medical science : AMS
  • [ISO-abbreviation] Arch Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Other-IDs] NLM/ PMC3278958
  • [Keywords] NOTNLM ; Cowden syndrome / PTEN gene / Polish population
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15. Dutta S, Nehra D, Woo R, Cohen I: Laparoscopic resection of a benign liver tumor in a child. J Pediatr Surg; 2007 Jun;42(6):1141-5
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  • The authors report a case of nonanatomical laparoscopic hepatic resection of a large mesenchymal hamartoma in a 2-year-old boy.
  • [MeSH-major] Hamartoma / surgery. Hepatectomy / methods. Laparoscopy / methods. Liver Diseases / surgery

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  • (PMID = 17560238.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Woertler K: Tumors and tumor-like lesions of peripheral nerves. Semin Musculoskelet Radiol; 2010 Nov;14(5):547-58
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  • This article reviews the MR imaging appearance, clinical and pathological features of schwannoma, localized neurofibroma, plexiform neurofibroma, intraneural perineurioma, fibrolipomatous hamartoma, nerve sheath ganglion, traumatic neuroma, malignant peripheral nerve sheath tumor, and secondary malignant neoplasms of peripheral nerves.

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  • [Copyright] © Thieme Medical Publishers.
  • (PMID = 21072731.001).
  • [ISSN] 1098-898X
  • [Journal-full-title] Seminars in musculoskeletal radiology
  • [ISO-abbreviation] Semin Musculoskelet Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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17. Vernia P, Marcheggiano A, Marinaro V, Morabito S, Guzzo I, Pierucci A: Is Cronkhite-Canada Syndrome necessarily a late-onset disease? Eur J Gastroenterol Hepatol; 2005 Oct;17(10):1139-41
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  • [Title] Is Cronkhite-Canada Syndrome necessarily a late-onset disease?
  • Cronkhite-Canada Syndrome is a non-inherited, non-congenital disease characterized by juvenile hamartomatous gastrointestinal polyps with a typically late onset.
  • In the case described herein the disease was diagnosed in a 17-year-old male with type I diabetes and thalassaemia minor, in coincidence with severe symptomatic intestinal candidiasis.
  • The concept that Cronkhite-Canada Syndrome is a late-onset disease should probably be reconsidered as it may remain asymptomatic, and thus not diagnosed, for a long a time.

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  • (PMID = 16148564.001).
  • [ISSN] 0954-691X
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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18. Tagliani MM, Gomide MR, Carrara CF: Oral-facial-digital syndrome type 1: oral features in 12 patients submitted to clinical and radiographic examination. Cleft Palate Craniofac J; 2010 Mar;47(2):162-6
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  • The most frequent findings were tongue hamartomas, multiple buccal frena, asymmetric lips, asymmetric tongue, and bilateral maxillary gingival swelling.

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  • (PMID = 20210637.001).
  • [ISSN] 1545-1569
  • [Journal-full-title] The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
  • [ISO-abbreviation] Cleft Palate Craniofac. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Orofaciodigital syndrome type1
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19. Kelekci S, Yazicioglu HF, Yilmaz B, Aygün M, Omeroglu RE: Cardiac rhabdomyoma with tuberous sclerosis: a case report. J Reprod Med; 2005 Jul;50(7):550-2
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  • Postnatal echocardiography confirmed the presence of cardiac rhabdomyoma, and periventricular subependymal multiple hamartomas were diagnosed by postnatal magnetic resonance imaging.
  • [MeSH-minor] Adult. Female. Hamartoma / diagnosis. Hamartoma / embryology. Heart Septum. Heart Ventricles. Humans. Infant, Newborn. Magnetic Resonance Imaging. Pregnancy. Pregnancy Outcome. Ultrasonography, Prenatal


20. Kutlu G, Bilir E, Erdem A, Gomceli YB, Leventoglu A, Kurt GS, Karatas A, Serdaroglu A: Temporal lobe ictal behavioral patterns in hippocampal sclerosis and other structural abnormalities. Epilepsy Behav; 2005 May;6(3):353-9
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  • Two hundred and two seizures in 35 patients with hippocampal sclerosis (Group 1) and eighty seizures in 13 patients with other pathological findings, such as tumors, cavernoma, and hamartoma (Group 2), were analyzed.

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  • (PMID = 15820343.001).
  • [ISSN] 1525-5050
  • [Journal-full-title] Epilepsy & behavior : E&B
  • [ISO-abbreviation] Epilepsy Behav
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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21. Mehenni H, Resta N, Park JG, Miyaki M, Guanti G, Costanza MC: Cancer risks in LKB1 germline mutation carriers. Gut; 2006 Jul;55(7):984-90
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  • BACKGROUND AND AIMS: Germline mutations in the LKB1 gene are known to cause Peutz-Jeghers syndrome, which is an autosomal dominant disorder characterised by hamartomatous polyposis and mucocutaneous pigmentation.
  • [MeSH-minor] Age Distribution. Breast Neoplasms / genetics. Chi-Square Distribution. Cohort Studies. DNA Mutational Analysis. Female. Gastrointestinal Neoplasms / genetics. Genetic Predisposition to Disease. Heterozygote. Humans. Male. Risk Assessment. Sex Distribution

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  • (PMID = 16407375.001).
  • [ISSN] 0017-5749
  • [Journal-full-title] Gut
  • [ISO-abbreviation] Gut
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.7.1.- / STK11 protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
  • [Other-IDs] NLM/ PMC1856321
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22. Postgate AJ, Will OC, Fraser CH, Fitzpatrick A, Phillips RK, Clark SK: Capsule endoscopy for the small bowel in juvenile polyposis syndrome: a case series. Endoscopy; 2009 Nov;41(11):1001-4
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  • Juvenile polyposis syndrome is one of the hamartomatous polyposis syndromes and demonstrates phenotypic heterogeneity.

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  • [Copyright] Georg Thieme Verlag KG Stuttgart. New York.
  • (PMID = 19816839.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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23. Wei C, Amos CI, Zhang N, Wang X, Rashid A, Walker CL, Behringer RR, Frazier ML: Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling. Clin Cancer Res; 2008 Feb 15;14(4):1167-71
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  • PURPOSE: Peutz-Jeghers syndrome (PJS) is a unique disorder characterized by the development of hamartomas in the gastrointestinal tract as well as increased risks for variety of malignancies.

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  • (PMID = 18281551.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA16672; United States / NCI NIH HHS / CA / R03 CA123603; United States / NCI NIH HHS / CA / R03 CA89843
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; EC 2.7.- / Protein Kinases; EC 2.7.1.- / Stk11 protein, mouse; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.1.1 / mTOR protein, mouse; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; W36ZG6FT64 / Sirolimus
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24. Ma L, Teruya-Feldstein J, Bonner P, Bernardi R, Franz DN, Witte D, Cordon-Cardo C, Pandolfi PP: Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer. Cancer Res; 2007 Aug 1;67(15):7106-12
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  • Importantly, our results indicate that Erk-mediated phosphorylation and inactivation of TSC2 can be critical in development of hamartomatous lesions in TSC and cancer pathogenesis.


25. Pérez Rodríguez MJ, Anaya Barea FM, Galiano Fernández E, de Diego Sierra D, Condado Sánchez-Rojas I: [Peutz-Jeghers syndrome]. An Pediatr (Barc); 2008 Apr;68(4):369-72
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  • Peutz-Jeghers syndrome is an inherited disorder which usually debuts during childhood.
  • It is characterized by mucocutaneous pigmentation and hamartomatous polyps in the gastrointestinal tract.
  • [MeSH-minor] Child. Diagnosis, Differential. Disease Progression. Humans. Male. Melanosis / diagnosis. Severity of Illness Index

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  • (PMID = 18394383.001).
  • [ISSN] 1695-4033
  • [Journal-full-title] Anales de pediatría (Barcelona, Spain : 2003)
  • [ISO-abbreviation] An Pediatr (Barc)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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26. Movahedi N, Boroumand MA, Sotoudeh Anvari M, Yazdanifard P: Mature cardiac myocyte hamartoma in the right atrium. Asian Cardiovasc Thorac Ann; 2008 Oct;16(5):e47-8
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  • [Title] Mature cardiac myocyte hamartoma in the right atrium.
  • It was composed of disorganized hypertrophic mature cardiac myocytes, and associated with focal fibrosis, mature adipocytes, and mild lymphocytic infiltration in peripheral areas, indicative of cardiac hamartoma.
  • This type of hamartoma has been rarely reported as an isolated mass in the right atrium.
  • [MeSH-major] Cardiomyopathies / pathology. Hamartoma / pathology. Incidental Findings. Myocytes, Cardiac / pathology

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  • (PMID = 18812338.001).
  • [ISSN] 1816-5370
  • [Journal-full-title] Asian cardiovascular & thoracic annals
  • [ISO-abbreviation] Asian Cardiovasc Thorac Ann
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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27. Conrad DM, Chaplin A, Walsh NM, Pasternak S: Extensive neurocristic hamartoma with bone marrow involvement. Am J Dermatopathol; 2010 Jul;32(5):486-8
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  • [Title] Extensive neurocristic hamartoma with bone marrow involvement.
  • Cutaneous neurocristic hamartoma (NCH) is a rare, pigmented lesion consisting of cells that aberrantly develop from the neurocrest.
  • [MeSH-major] Bone Marrow / pathology. Hamartoma / pathology. Nevus, Blue / pathology. Skin Neoplasms / pathology

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  • (PMID = 20414093.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Chen YY, Tiang XY, Li Z, Luo BN, Huang Q: Sporadic meningioangiomatosis-associated atypical meningioma mimicking parenchymal invasion of brain: a case report and review of the literature. Diagn Pathol; 2010;5:39
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  • Meningioangiomatosis is a rare hamartomatous lesion or meningiovascular malformation in brain.

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29. Aretz S: The differential diagnosis and surveillance of hereditary gastrointestinal polyposis syndromes. Dtsch Arztebl Int; 2010 Mar;107(10):163-73
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  • Except in cases of mild adenomatous polyposis, phenotypic overlap among the hamartomatous polyposes often causes difficulties in differential diagnosis.

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  • (PMID = 20358032.001).
  • [ISSN] 1866-0452
  • [Journal-full-title] Deutsches Ärzteblatt international
  • [ISO-abbreviation] Dtsch Arztebl Int
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 44
  • [Other-IDs] NLM/ PMC2847323
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30. Vidal I, Podevin G, Piloquet H, Le Rhun M, Frémond B, Aubert D, Leclair MD, Héloury Y: Follow-up and surgical management of Peutz-Jeghers syndrome in children. J Pediatr Gastroenterol Nutr; 2009 Apr;48(4):419-25
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  • Diagnosis was based on at least 1 hamartomatous polyp associated with 2 of the 3 following criteria: family record of PJS, polyposis localised on small bowel, and mucocutaneous pigmentation.

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  • (PMID = 19330929.001).
  • [ISSN] 1536-4801
  • [Journal-full-title] Journal of pediatric gastroenterology and nutrition
  • [ISO-abbreviation] J. Pediatr. Gastroenterol. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.1.- / STK11 protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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31. Dorfmüller G, Fohlen M, Bulteau C, Delalande O: [Surgical disconnection of hypothalamic hamartomas]. Neurochirurgie; 2008 May;54(3):315-9
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  • [Title] [Surgical disconnection of hypothalamic hamartomas].
  • [Transliterated title] Déconnexion chirurgicale des hamartomes hypothalamiques.
  • BACKGROUND AND PURPOSE: Surgical resection of hypothalamic hamartomas (HHs) associated with drug-resistant gelastic epilepsy carries a considerable risk of neurological and endocrine morbidity.
  • The hamartoma was disconnected using a microsurgical pterional approach of those lesions extending from the hypothalamic floor downward into the interpeduncular cistern.
  • According to the different topographic features of the HHs, for which we have recently proposed a classification into four subtypes, the intraventricularly located hamartoma had the best prognosis following endoscopic disconnection.
  • [MeSH-major] Hamartoma / surgery. Hypothalamic Diseases / surgery. Neurosurgical Procedures

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  • (PMID = 18452954.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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32. Kaspareit J, Friderichs-Gromoll S, Buse E, Habermann G: Spontaneous neoplasms observed in cynomolgus monkeys (Macaca fascicularis) during a 15-year period. Exp Toxicol Pathol; 2007 Nov;59(3-4):163-9
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  • Most of the tumors (22) in the cynomolgus monkeys were seen in endocrine organs (adrenal cortical adenoma, adrenal hemangioma, C-cell carcinoma, follicular adenoma), respiratory system (nasal cavity adenoma, pulmonary squamous cell carcinoma, bronchio-alveolar carcinoma, bronchiolar papilloma, chondromatous hamartoma) and female genital system (uterine polyp, uterine adenoma, uterine leiomyoma and teratoma of the ovary).

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  • (PMID = 17869495.001).
  • [ISSN] 0940-2993
  • [Journal-full-title] Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie
  • [ISO-abbreviation] Exp. Toxicol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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33. Feller L, Kramer B, Raubenheimer EJ, Lemmer J: Enamel dysplasia with hamartomatous atypical follicular hyperplasia (EDHFH) syndrome: suggested pathogenic mechanisms. SADJ; 2008 Mar;63(2):102-5
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  • [Title] Enamel dysplasia with hamartomatous atypical follicular hyperplasia (EDHFH) syndrome: suggested pathogenic mechanisms.
  • The syndrome of enamel dysplasia with hamartomatous atypical follicular hyperplasia (EDHFH) is an unusual syndrome and is unique to black South Africans.
  • [MeSH-major] Dental Enamel Hypoplasia / etiology. Dental Enamel Proteins / biosynthesis. Dental Sac / pathology. Hamartoma / etiology. Tooth, Impacted / etiology

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  • (PMID = 18561809.001).
  • [ISSN] 1029-4864
  • [Journal-full-title] SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging
  • [ISO-abbreviation] SADJ
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] South Africa
  • [Chemical-registry-number] 0 / Dental Enamel Proteins
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34. Skowron F, Balme B: Large plaque-type blue naevus with subcutaneous cellular nodules. Clin Exp Dermatol; 2009 Dec;34(8):e782-4
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  • In cases of PBTN lesions on the head, clinicians must keep in mind the risk of malignant transformation of PTBN or an association with cutaneous neurocristic hamartoma.

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  • (PMID = 19817763.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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35. Fujimoto K: Usefulness of contrast-enhanced magnetic resonance imaging for evaluating solitary pulmonary nodules. Cancer Imaging; 2008;8:36-44
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  • Chest computed tomography (CT) is considered the standard technique for assessing morphologic findings and intrathoracic spread of an SPN.
  • Dynamic MRI and dynamic CT are useful for differentiating between malignant and benign SPNs (especially tuberculomas and hamartomas).
  • [MeSH-minor] Adenocarcinoma, Bronchiolo-Alveolar / diagnosis. Carcinoma, Non-Small-Cell Lung / metabolism. Contrast Media. Diagnosis, Differential. Gadolinium. Hamartoma / diagnosis. Humans. Lung Diseases / diagnosis. Pneumonia, Pneumococcal / diagnosis. Positron-Emission Tomography. Prognosis. Sensitivity and Specificity. Tomography, X-Ray Computed. Tuberculoma / diagnosis. Vascular Endothelial Growth Factor A / metabolism

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  • (PMID = 18331971.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Vascular Endothelial Growth Factor A; AU0V1LM3JT / Gadolinium
  • [Number-of-references] 41
  • [Other-IDs] NLM/ PMC2267694
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36. Gao H, van Lier MG, Poley JW, Kuipers EJ, van Leerdam ME, Mensink PB: Endoscopic therapy of small-bowel polyps by double-balloon enteroscopy in patients with Peutz-Jeghers syndrome. Gastrointest Endosc; 2010 Apr;71(4):768-73
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  • BACKGROUND: Peutz-Jeghers syndrome (PJS) is a hereditary disorder characterized by mucocutaneous pigmentations and hamartomatous polyps mainly in the small bowel.

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  • [Copyright] Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20188368.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.1.- / STK11 protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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37. Gammon A, Kohlmann W, Burt R: Can we identify the high-risk patients to be screened? A genetic approach. Digestion; 2007;76(1):7-19
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  • Other rare syndromes (the hamartomatous polyposis syndromes) will be summarized in table form.
  • [MeSH-major] Colorectal Neoplasms / genetics. Colorectal Neoplasms / prevention & control. Genetic Predisposition to Disease. Genetic Testing. Neoplastic Syndromes, Hereditary / diagnosis. Neoplastic Syndromes, Hereditary / genetics

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  • [Copyright] (c) 2007 S. Karger AG, Basel.
  • (PMID = 17947814.001).
  • [ISSN] 1421-9867
  • [Journal-full-title] Digestion
  • [ISO-abbreviation] Digestion
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P01-CA73992; United States / NCI NIH HHS / CA / P30-CA42014; United States / NCI NIH HHS / CA / R01-CA40641
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 27
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38. Bailey AA, Debinski HS, Appleyard MN, Remedios ML, Hooper JE, Walsh AJ, Selby WS: Diagnosis and outcome of small bowel tumors found by capsule endoscopy: a three-center Australian experience. Am J Gastroenterol; 2006 Oct;101(10):2237-43
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  • Nine tumors were proven benign: hamartoma (4), cystic lymphangioma (1), primary amyloid (1), lipoma (1).
  • Of the five patients with primary adenocarcinoma only one remains disease free.
  • Both patients with GIST are disease free.
  • CONCLUSIONS: Small bowel tumors are a significant finding at CE and are often missed by other methods of investigation.
  • Even in malignant lesions, treatment is potentially curative in the absence of metastatic disease.

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  • (PMID = 17032187.001).
  • [ISSN] 0002-9270
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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39. Karpelowsky JS, Pansini A, Lazarus C, Rode H, Millar AJ: Difficulties in the management of mesenchymal hamartomas. Pediatr Surg Int; 2008 Oct;24(10):1171-5
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  • [Title] Difficulties in the management of mesenchymal hamartomas.
  • AIM: Mesenchymal hamartoma of the liver is an entity with a varied presentation and frequent initial delay in diagnosis.
  • We look at a single centre experience with the mesenchymal hamartomas.
  • RESULTS: Seventeen patients aged 1 day to 15 years were identified, with a histopathological diagnosis of mesenchymal hamartoma of the liver.
  • The tumours were all confirmed as mesenchymal hamartomas; size ranged from 412 to 2,230 g.
  • Complications included three related to misdiagnosis (hydatid disease, and hepatoblastoma).
  • CONCLUSION: Although hamartomas of the liver are histologically benign, their clinical course and the complications of surgical treatment can be significant.
  • [MeSH-major] Hamartoma / pathology. Hamartoma / surgery. Intraoperative Complications. Liver Diseases / pathology. Liver Diseases / surgery. Postoperative Complications

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  • (PMID = 18751987.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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40. Seith A, Kandpal H, Khadgawat R: Hypothalamic hamartoma: MR imaging and MR spectroscopic features. Singapore Med J; 2008 Apr;49(4):366-7
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  • [Title] Hypothalamic hamartoma: MR imaging and MR spectroscopic features.
  • [MeSH-major] Hamartoma / diagnosis. Hamartoma / pathology. Hypothalamic Diseases / diagnosis. Hypothalamic Diseases / pathology

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  • (PMID = 18418535.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Singapore
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41. Tosios KI, Koutlas IG, Kyriakopoulos VF, Balta M, Theologie-Lygidakis N, Vardas E, Iatrou I: Time to abandon the term angiomyolipoma for non-PEComatous angiomyomatous (or angiomatous) oral tumors with adipocytes. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Oct;110(4):492-7
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  • Herein, through review of the pertinent oral pathology literature and the detailed description of 2 lesions, one an oral angiomyoma with an adipocytic component and the other an apparently hamartomatous angioleiomyomatous proliferation with adipocytes, we provide, in our opinion, a solid argument against the use of the term AML for non-PEComatous oral tumors.

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  • [Copyright] Copyright © 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20674420.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Desmin; 0 / S100 Proteins; 0 / von Willebrand Factor
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42. Hoogeveen-Westerveld M, Exalto C, Maat-Kievit A, van den Ouweland A, Halley D, Nellist M: Analysis of TSC1 truncations defines regions involved in TSC1 stability, aggregation and interaction. Biochim Biophys Acta; 2010 Sep;1802(9):774-81
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  • Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterised by the development of hamartomas in a variety of organs and tissues.
  • The disease is caused by mutations in either the TSC1 gene on chromosome 9q34, or the TSC2 gene on chromosome 16p13.3.

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20547222.001).
  • [ISSN] 0006-3002
  • [Journal-full-title] Biochimica et biophysica acta
  • [ISO-abbreviation] Biochim. Biophys. Acta
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Mutant Proteins; 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein
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43. Chouchane Mlik O, Lardenois S, Salmon R, Servois V, Sastre-Garau X: [Sclerosing angiomatoid nodular transformation of the spleen]. Ann Pathol; 2008 Sep;28(4):317-20
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  • In this report, we discuss the pathology of this lesion and the differential diagnosis of SANT with other lesions such as hemangiomas, hamartomas and inflammatory pseudotumors.

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  • (PMID = 18928874.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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44. Hur S, Han JK, Kim MA, Bae JM, Choi BI: Brunner's gland hamartoma: computed tomographic findings with histopathologic correlation in 9 cases. J Comput Assist Tomogr; 2010 Jul;34(4):543-7
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  • [Title] Brunner's gland hamartoma: computed tomographic findings with histopathologic correlation in 9 cases.
  • OBJECTIVE: To describe the computed tomographic (CT) features of Brunner's gland hamartoma with histopathologic correlation.
  • METHODS: The CT images of 9 patients with pathologically proven Brunner's gland hamartoma were reviewed retrospectively.
  • RESULTS: Brunner's gland hamartomas presented as small (mean, 1.9 cm) Yamada type II or III (67%, 6/9) polyps with frequent internal cyst (33%, 3/9).
  • CONCLUSIONS: In a patient with asymptomatic small submucosal mass in the duodenal first or second portion, hypoattenuated mass with peripheral rimlike enhancement or internal cystic change suggests the possibility of Brunner's gland hamartoma.
  • [MeSH-major] Brunner Glands / radiography. Duodenal Diseases / radiography. Hamartoma / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 20657222.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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45. Itin PH: Happle-Tinschert syndrome. Segmentally arranged basaloid follicular hamartomas, linear atrophoderma with hypo- and hyperpigmentation, enamel defects, ipsilateral hypertrichosis, and skeletal and cerebral anomalies. Dermatology; 2009;218(3):221-5
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  • [Title] Happle-Tinschert syndrome. Segmentally arranged basaloid follicular hamartomas, linear atrophoderma with hypo- and hyperpigmentation, enamel defects, ipsilateral hypertrichosis, and skeletal and cerebral anomalies.
  • Recently, Happle and Tinschert [Acta Derm Venereol 2008;88:382-387] described the case of a multisystem birth defect with segmentally arranged basaloid follicular hamartomas associated with extracutaneous defects in the form of short leg, polydactyly and hypoplastic teeth.
  • A 7-year-old boy had multiple whitish and some scattered brownish basaloid follicular hamartomas involving the right side of his body in a systematized pattern following the lines of Blaschko.
  • The molecular basis of the disorder remains to be elucidated.
  • [MeSH-major] Abnormalities, Multiple. Bone and Bones / abnormalities. Brain Neoplasms. Hamartoma / pathology. Medulloblastoma. Pigmentation Disorders / pathology. Skin Diseases / pathology. Tooth Abnormalities

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  • [Copyright] 2008 S. Karger AG, Basel
  • (PMID = 19005246.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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46. Gleizal A, Chekaroua K, Beziat JL, Delay E: [Evolution of sebaceous hamartoma: prospective pathologic study illustrated with a voluminous ear location]. Ann Chir Plast Esthet; 2005 Dec;50(6):739-42
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  • [Title] [Evolution of sebaceous hamartoma: prospective pathologic study illustrated with a voluminous ear location].
  • [Transliterated title] Devenir des hamartomes sébacés: une étude anatomopathologigue prospective illustrée par un cas volumineux de la région auriculaire.
  • After an exeresis of a sebaceous hamartoma of retroauricular area, histologic examination showed a trichoblastoma mimicking a basal cell carcinoma.
  • So we realized a retrospective study with histologic examination of 24 cases of basal cell carcinoma after hamartoma.
  • So the study goes in the same direction of the world literature: hamartoma have a minimal risk of basal cell carcinoma transformation.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Hamartoma / pathology. Hamartoma / surgery. Sebaceous Gland Diseases / pathology. Sebaceous Gland Diseases / surgery

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  • (PMID = 16153762.001).
  • [ISSN] 0294-1260
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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47. Kazakov DV, Vanecek T, Nemcova J, Kacerovska D, Spagnolo DV, Mukensnabl P, Michal M: Spectrum of tumors with follicular differentiation in a patient with the clinical phenotype of multiple familial trichoepitheliomas: a clinicopathological and molecular biological study, including analysis of the CYLD and PTCH genes. Am J Dermatopathol; 2009 Dec;31(8):819-27
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  • We report a patient with multiple trichoepitheliomas whose biopsy material also demonstrated a range of other neoplasms with follicular differentiation, including small nodular trichoblastoma, small nodular basal cell carcinoma (BCC), and areas resembling infundibulocystic BCC/basaloid follicular hamartoma.

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  • (PMID = 19730223.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CYLD protein, human; 0 / Receptors, Cell Surface; 0 / Tumor Suppressor Proteins; 0 / patched receptors
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48. Quintella C, Damante JH, Janson G, Guerra E, de Freitas MR, Starling C: Orthodontic therapy in patients with pericoronal hamartoma. Am J Orthod Dentofacial Orthop; 2008 May;133(5):758-61
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  • [Title] Orthodontic therapy in patients with pericoronal hamartoma.
  • Pericoronal hamartoma is a special type of pericoronal lesion, and little information about it is available in the orthodontic literature.
  • This report presents a patient with pericoronal hamartoma on the mandibular left permanent first molar who had orthodontic treatment.
  • Because of the similarity of the radiographic radiolucency of pericoronal hamartoma and other lesions, a differential diagnosis must be made to avoid extraction of permanent teeth.
  • [MeSH-major] Dental Sac / pathology. Hamartoma / complications. Orthodontics, Corrective / methods. Tooth, Unerupted / complications

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  • (PMID = 18456152.001).
  • [ISSN] 1097-6752
  • [Journal-full-title] American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
  • [ISO-abbreviation] Am J Orthod Dentofacial Orthop
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Mahouachi R, Ben Abdelkrim I, Chtourou A, Taktak S, Elgharbi R, Kallel H, Drira I, Ben Kheder A: [Lung cancer and chondromatous hamartoma: a case report]. Tunis Med; 2005 Dec;83(12):789-91
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  • [Title] [Lung cancer and chondromatous hamartoma: a case report].
  • The association lung cancer with chondromatous hamartoma is frequent.
  • We present a case of synchronous primary lung adenocarcinoma and chondromatous hamartoma.
  • Although hamartoma is generally considered to be a benign tumor, there have been several reports of increased risk of lung cancer in patients with a chondromatous hamartoma.
  • Therefore we recommend that patients with hamartoma should be submitted to a complete evaluation and to regular follow up, considering the risk of associated synchronous malignancy.
  • [MeSH-major] Adenocarcinoma. Hamartoma. Lung Diseases. Lung Neoplasms

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  • (PMID = 16450951.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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50. Kim SH, Kim WS, Cheon JE, Yoon HK, Kang GH, Kim IO, Yeon KM: Radiological spectrum of hepatic mesenchymal hamartoma in children. Korean J Radiol; 2007 Nov-Dec;8(6):498-505
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  • [Title] Radiological spectrum of hepatic mesenchymal hamartoma in children.
  • OBJECTIVE: A hepatic mesenchymal hamartoma is an uncommon benign tumor in children and little is known about the spectrum of its radiological features.
  • The purpose of this study is to describe the spectrum of radiological features of a hepatic mesenchymal hamartoma in children.
  • MATERIALS AND METHODS: Thirteen children with a pathologically confirmed hepatic mesenchymal hamartoma (M:F = 7:6; mean age, 3 years 2 months) were included in our study.
  • We evaluated the imaging findings of the hepatic mesenchymal hamartomas and the corresponding pathological features.
  • CONCLUSION: A hepatic mesenchymal hamartoma in children can show a wide spectrum of radiological features, from a multiseptated cystic tumor to a mixed solid and cystic tumor, and even a solid tumor.
  • [MeSH-major] Hamartoma / diagnosis. Liver / radiography. Liver Neoplasms / diagnosis. Mesoderm / radiography

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  • (PMID = 18071280.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Contrast Media
  • [Other-IDs] NLM/ PMC2627452
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51. Stafyla V, Kotsifopoulos N, Grigoriadis K, Bakoyiannis CN, Peros G, Sakorafas GH: Myoid hamartoma of the breast: a case report and review of the literature. Breast J; 2007 Jan-Feb;13(1):85-7
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  • [Title] Myoid hamartoma of the breast: a case report and review of the literature.
  • Myoid hamartomas of the breast are extremely rare breast lesions, with a poorly understood pathogenesis.
  • Histological and immunohistochemical findings established the diagnosis of myoid hamartoma.
  • Breast myoid hamartomas are exceptionally rare benign lesions; complete surgical excision achieves cure.
  • [MeSH-major] Breast Neoplasms / diagnosis. Hamartoma / diagnosis

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  • (PMID = 17214800.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
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52. Skrovina M, Czudek S, Bartos J, Ferák I, Adamcík L, Bezunková E, Vanko R: [The Peutz-Jeghers syndrome--a case review]. Rozhl Chir; 2007 Jan;86(1):24-6
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  • The final histological finding diagnosed solitary hamartoma of the Peutz-Jeghers polyp.
  • [MeSH-major] Diagnostic Errors. Hamartoma / diagnosis. Intestinal Polyps / diagnosis. Peutz-Jeghers Syndrome / diagnosis

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  • (PMID = 17416075.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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53. Carvounis E, Marinis A, Arkadopoulos N, Theodosopoulos T, Smyrniotis V: Vascular adrenal cysts: a brief review of the literature. Arch Pathol Lab Med; 2006 Nov;130(11):1722-4
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  • Adrenal vascular cysts probably originate from a preexisting vascular hamartoma.

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  • (PMID = 17076539.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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54. Coriat R, Mozer-Bernardeau M, Terris B, Chryssostalis A, Prat F, Chaussade S: Endoscopic resection of a large Brunner's gland hamartoma. Gastroenterol Clin Biol; 2008 Jan;32(1 Pt. 1):11-4
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  • [Title] Endoscopic resection of a large Brunner's gland hamartoma.
  • Brunner's Gland Hamartoma (BGH) is a benign tumor of the duodenum that can lead to gastrointestinal bleeding and intestinal obstruction.
  • [MeSH-major] Brunner Glands / surgery. Duodenal Diseases / surgery. Duodenoscopy / methods. Hamartoma / surgery

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  • (PMID = 18341972.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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55. Janssen R, Geukens A, Brugman T: Hand-assisted laparoscopic splenectomy for a splenic hamartoma: two case reports. Acta Chir Belg; 2008 Mar-Apr;108(2):254-7
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  • [Title] Hand-assisted laparoscopic splenectomy for a splenic hamartoma: two case reports.
  • We present two patients, each with a hamartoma of the spleen.
  • [MeSH-major] Hamartoma / surgery. Splenectomy / methods. Splenic Diseases / surgery

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  • (PMID = 18557155.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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56. Carranza Carranza A, Salinas Martín MV, Sánchez Bernal ML, Fernández Alonso J: [Infected pseudotumoral bile duct hamartomas in polycystic liver]. Gastroenterol Hepatol; 2007 Jun-Jul;30(6):372-3
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  • [Title] [Infected pseudotumoral bile duct hamartomas in polycystic liver].
  • [MeSH-major] Bile Duct Diseases / complications. Cysts / complications. Hamartoma / complications. Liver Diseases / complications

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  • (PMID = 17662224.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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57. Schwartz TH: Treatment options for hypothalamic hamartomas--no laughing matter. Epilepsy Curr; 2007 May-Jun;7(3):72-4
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  • [Title] Treatment options for hypothalamic hamartomas--no laughing matter.

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  • (PMID = 17520079.001).
  • [ISSN] 1535-7597
  • [Journal-full-title] Epilepsy currents
  • [ISO-abbreviation] Epilepsy Curr
  • [Language] ENG
  • [Publication-type] Comment; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1874321
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58. Chen X, Liu HY, Li Y: [Retroperitoneal laparoscopic enucleation of the renal hamartoma]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2006 Aug;31(4):604-6
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  • [Title] [Retroperitoneal laparoscopic enucleation of the renal hamartoma].
  • OBJECTIVE: To investigate the operative technique and the clinical value of retroperitoneal laparoscopic enucleation of the renal hamartoma.
  • METHODS: Twenty-five patients of renal hamartoma received retroperitoneal laparoscopic enucleation.
  • The renal hamartoma was confirmed through a pathological diagnosis during the operation.
  • CONCLUSION: Retroperitoneal laparoscopic enucleation of the renal hamartoma is safe and effective, whose advantages include minimal invasive, less blood loss, short hospital stay, and rapid convalescence.
  • [MeSH-major] Hamartoma / surgery. Kidney Diseases / surgery. Laparoscopy

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  • (PMID = 16951530.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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59. Hulsmann AR, de Bont N, den Hollander JC, Borgstein JA: Hamartomas of the oro- and nasopharyngeal cavity in infancy: two cases and a short review. Eur J Pediatr; 2009 Aug;168(8):999-1001
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  • [Title] Hamartomas of the oro- and nasopharyngeal cavity in infancy: two cases and a short review.
  • DISCUSSION: As shown by our cases, the clinical presentation of an oropharyngeal mass in infancy varies from respiratory insufficiency at birth to incidental finding by the parents a few months after birth.
  • [MeSH-major] Dermoid Cyst / pathology. Esophageal Neoplasms / pathology. Hamartoma / pathology. Oropharyngeal Neoplasms / pathology. Otorhinolaryngologic Diseases / pathology

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  • (PMID = 18987884.001).
  • [ISSN] 1432-1076
  • [Journal-full-title] European journal of pediatrics
  • [ISO-abbreviation] Eur. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
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60. Ikegami R, Watanabe Y, Tainaka T: Myoepithelial hamartoma causing small-bowel intussusception: a case report and literature review. Pediatr Surg Int; 2006 Apr;22(4):387-9
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  • [Title] Myoepithelial hamartoma causing small-bowel intussusception: a case report and literature review.
  • Myoepithelial hamartoma was diagnosed histopathologically.
  • [MeSH-major] Hamartoma / complications. Intestinal Obstruction / etiology. Intestine, Small / surgery. Intussusception / etiology. Myoepithelioma / complications

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  • (PMID = 16572349.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 19
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61. Kakizaki F, Aoki K, Miyoshi H, Carrasco N, Aoki M, Taketo MM: CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium. Gastroenterology; 2010 Feb;138(2):627-35
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  • Slc5a8 levels were also reduced in colonic adenomatous polyps and hamartomas from Apc(+/Delta716) and Cdx2(+/-) mutant mice, respectively, compared with adjacent normal colon tissues.

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  • (PMID = 19900445.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cation Transport Proteins; 0 / Cdx1 protein, mouse; 0 / Cdx2 protein, mouse; 0 / Homeodomain Proteins; 0 / Slc5a8 protein, mouse; 0 / Transcription Factors
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62. Stoffelns BM, Schöpfer K, Kramann C: [Pseudomelanomas of the choroid]. Klin Monbl Augenheilkd; 2007 Apr;224(4):274-8
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  • Rare diagnoses were orbital tumour, scleritis posterior and a combined hamartoma of retina and pigment epithelium (4 % at all).

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  • (PMID = 17458791.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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63. Lavín Castejón I, Mut Oltra J, Trillo Balizón C, Maldonado Barrionuevo A: [Lhermitte-Duclos's disease associated to Cowden s disease: a case report]. An Med Interna; 2007 May;24(5):239-41
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  • [Title] [Lhermitte-Duclos's disease associated to Cowden s disease: a case report].
  • Cowden's disease is a rare genodermatosis that is characterized for multiple cutaneous and visceral hamartoma .
  • Lhermitte-Duclos's disease is a cerebelous lesion that consists in the displasic enlargement of the cerebelous circumvolution.
  • It's incluyed in phacomatosis and usually presents associated to Cowden's disease, tuberous sclerosis and overlap syndromes.A 56 years old man, diagnosed in Dermatology with Cowden's disease ten years ago.
  • In the extension study, he had hamartoma intestinal polip, esophagic glucogenic acanthosis and two solid thyroid nodules.
  • [MeSH-major] Cerebellar Neoplasms / complications. Ganglioneuroma / complications. Hamartoma Syndrome, Multiple / complications

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  • (PMID = 17907890.001).
  • [ISSN] 0212-7199
  • [Journal-full-title] Anales de medicina interna (Madrid, Spain : 1984)
  • [ISO-abbreviation] An Med Interna
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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64. Jacob S, Mohapatra D, Verghese M: Massive chondroid hamartoma of the lung clinically masquerading as bronchogenic carcinoma. Indian J Pathol Microbiol; 2008 Jan-Mar;51(1):61-2
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  • [Title] Massive chondroid hamartoma of the lung clinically masquerading as bronchogenic carcinoma.
  • Chondroid hamartomas of the lung are uncommon lesions which are generally small sized and asymptomatic.
  • Herein we describe a case of a large-sized pulmonary chondroid hamartoma which clinically mimicked bronchogenic carcinoma.
  • [MeSH-major] Hamartoma / diagnosis. Lung Diseases / pathology

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  • (PMID = 18417859.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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65. Leboeuf NR, Mahalingam M: Acanthomatous superficial sebaceous hamartoma? A study of six cases with clarification of the nomenclature. J Cutan Pathol; 2007 Nov;34(11):865-70
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  • [Title] Acanthomatous superficial sebaceous hamartoma? A study of six cases with clarification of the nomenclature.
  • [MeSH-major] Hamartoma / classification. Hamartoma / pathology. Sebaceous Gland Diseases / classification. Sebaceous Gland Diseases / pathology

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  • (PMID = 17944728.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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66. Inoue M, Hirakarta A, Iizuka N, Futagami S, Hida T: Tractional macular detachment associated with optic disc astrocytic hamartoma. Acta Ophthalmol; 2009 Mar;87(2):239-40
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  • [Title] Tractional macular detachment associated with optic disc astrocytic hamartoma.
  • [MeSH-major] Astrocytes / pathology. Hamartoma / complications. Macula Lutea. Optic Disk. Optic Nerve Diseases / complications. Retinal Detachment / complications. Retinoschisis / complications

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  • (PMID = 18577189.001).
  • [ISSN] 1755-3768
  • [Journal-full-title] Acta ophthalmologica
  • [ISO-abbreviation] Acta Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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67. Nicolau Y, Faquin WC, Deschler DG: Hamartoma of the parotid gland: report of a unique case. Ear Nose Throat J; 2010 May;89(5):E8-10
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  • [Title] Hamartoma of the parotid gland: report of a unique case.
  • Hamartomas of the parotid gland are very rare.
  • We present the case of a parotid gland hamartoma with oncocytic and sebaceous metaplasia arising as a 3-cm mass in a 70-year-old man.
  • We present this case to create awareness of hamartomas as part of the differential diagnosis of parotid masses.
  • [MeSH-major] Hamartoma / pathology. Parotid Diseases / pathology

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  • (PMID = 20461675.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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68. Steiner MA, Giles HW: Mesenchymal hamartoma of the liver demonstrating peripheral calcification in a 12-year-old boy. Pediatr Radiol; 2008 Nov;38(11):1232-4
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  • [Title] Mesenchymal hamartoma of the liver demonstrating peripheral calcification in a 12-year-old boy.
  • Mesenchymal hamartoma of the liver is a rare benign hepatic tumor that typically presents in the first 2 years of life.
  • Although spontaneous regression has been reported in this benign tumor, most mesenchymal hamartomas gradually increase in size and can reach enormous proportions.
  • We present an atypical case of mesenchymal hamartoma in a 12-year-old boy.
  • [MeSH-major] Hamartoma / diagnostic imaging. Liver Neoplasms / diagnostic imaging

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69. Ekinci S, Karnak I, Tanyel FC, Senocak ME, Kutluk T, Büyükpamukçu M, Büyükpamukçu N: Hepatic lobectomies in children: experience of a center in the light of changing management of malignant liver tumors. Pediatr Surg Int; 2006 Mar;22(3):228-32
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  • Pathological examination of resected tumors revealed hepatoblastoma (n=11), mesenchymal hamartoma (n = 5), hepatocellular carcinoma (n = 4), hemangioendothelioma (n=1), malignant mesenchymal tumor (n = 1), hemangioma (n = 1), cyst adenoma (n = 1), and metastasis of cellular mesoblastic nephroma (n = 1).

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  • [ErratumIn] Pediatr Surg Int. 2006 Aug;22(8):695
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  • (PMID = 16395609.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
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  • [Publication-country] Germany
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70. Siwanuwatn R, Deshmukh P, Feiz-Erfan I, Rekate HL, Zabramski JM, Spetzler RF, Rosenfeld JV: Microsurgical anatomy of the transcallosal anterior interforniceal approach to the third ventricle. Neurosurgery; 2005 Apr;56(2 Suppl):390-6; discussion 390-6
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  • OBJECTIVE: We explored relevant regional microanatomy as it relates to the challenging anterior interforniceal (AIF) approach for removing hypothalamic hamartomas.

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  • [ReprintIn] Neurosurgery. 2008 Jun;62(6 Suppl 3):1059-65 [18695526.001]
  • (PMID = 15794835.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Ng YT: A case of symptomatic, lesional epilepsy (hypothalamic hamartoma) masquerading as a generalized epilepsy with Lennox-Gastaut syndrome. Semin Pediatr Neurol; 2010 Mar;17(1):13-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of symptomatic, lesional epilepsy (hypothalamic hamartoma) masquerading as a generalized epilepsy with Lennox-Gastaut syndrome.
  • [MeSH-major] Epilepsy, Generalized / diagnosis. Hamartoma / diagnosis. Hypothalamic Neoplasms / diagnosis

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  • [CommentIn] Semin Pediatr Neurol. 2010 Mar;17(1):15-6 [20434686.001]
  • (PMID = 20434685.001).
  • [ISSN] 1558-0776
  • [Journal-full-title] Seminars in pediatric neurology
  • [ISO-abbreviation] Semin Pediatr Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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72. Makin E, Davenport M: Fetal and neonatal liver tumours. Early Hum Dev; 2010 Oct;86(10):637-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most frequently occurring are benign vascular tumours and mesenchymal hamartomas although malignancy in the form of hepatoblastoma is a possibility.
  • [MeSH-major] Fetal Diseases / diagnosis. Hamartoma / diagnosis. Hemangioendothelioma / diagnosis. Hepatoblastoma / diagnosis. Liver Neoplasms / diagnosis. Mesoderm / pathology

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20956063.001).
  • [ISSN] 1872-6232
  • [Journal-full-title] Early human development
  • [ISO-abbreviation] Early Hum. Dev.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
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73. Hassikou H, Tabache F, Safi S, Baaj M, Hadri L: Buschke-Ollendorff syndrome. Joint Bone Spine; 2008 Mar;75(2):212-4
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  • Buschke-Ollendorff syndrome (BOS) is an autosomal dominant disorder characterized by elastin-rich hamartomas and osteopoikilosis.
  • DISCUSSION: BOS is a rare disease that affects 1/20,000 population.
  • [MeSH-major] Chromosome Disorders / diagnosis. Hamartoma / diagnosis. Osteopoikilosis / radiography. Skin Diseases / diagnosis

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  • (PMID = 18313966.001).
  • [ISSN] 1778-7254
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / MAN1 protein, human; 0 / Membrane Proteins; 0 / Nuclear Proteins; 9007-34-5 / Collagen
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74. Picard A, Franchi G, Delbecque M, Sergent B, Buis J, Vazquez MP: [Scalp surgery in children: principles and therapeutic aspects]. Rev Stomatol Chir Maxillofac; 2005 Dec;106(6):334-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We reviewed our experience of 450 cases (1990-2000), and found that most common lesions in childhood were: sebaceous hamartoma, pigmentary naevus, post traumatic alopecia, aplasia cutis congenita and complicated hemangiomas.


75. Karabulut N, Bir F, Yuncu G, Kiter G: Endobronchial lipomatous hamartoma: an unusual cause of bronchial obstruction (2007: 7b). Eur Radiol; 2007 Oct;17(10):2687-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endobronchial lipomatous hamartoma: an unusual cause of bronchial obstruction (2007: 7b).
  • Imaging findings were reported in an unusual case of endobronchial lipomatous hamartoma obstructing the left mainstem bronchus.
  • Computed tomography readily demonstrated the presence of fat density within the lesion narrowing the differential diagnosis to endobronchial lipoma or lipomatous hamartoma.
  • [MeSH-major] Airway Obstruction / etiology. Bronchial Diseases / complications. Bronchial Diseases / diagnostic imaging. Hamartoma / complications. Hamartoma / diagnostic imaging. Tomography, X-Ray Computed

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76. Honkala H, Lahtela J, Fox H, Gentile M, Pakkasjärvi N, Salonen R, Wartiovaara K, Jauhiainen M, Kestilä M: Unraveling the disease pathogenesis behind lethal hydrolethalus syndrome revealed multiple changes in molecular and cellular level. Pathogenetics; 2009;2(1):2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unraveling the disease pathogenesis behind lethal hydrolethalus syndrome revealed multiple changes in molecular and cellular level.
  • Microscopically, immature cerebral cortex, abnormalities in radial glial cells and hypothalamic hamartoma are among key findings in the CNS of HLS fetuses.
  • RESULTS: To provide insight into the disease mechanism(s) of this lethal disorder we have studied different aspects of HLS and HYLS1.

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  • (PMID = 19400947.001).
  • [ISSN] 1755-8417
  • [Journal-full-title] PathoGenetics
  • [ISO-abbreviation] Pathogenetics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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77. Rosner M, Freilinger A, Hengstschläger M: Akt regulates nuclear/cytoplasmic localization of tuberin. Oncogene; 2007 Jan 25;26(4):521-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The autosomal dominantly inherited disease tuberous sclerosis (TSC) affects approximately 1 in 6000 individuals and is characterized by the development of tumors, named hamartomas, in different organs.

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  • (PMID = 16862180.001).
  • [ISSN] 0950-9232
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; 147604-94-2 / Cyclin-Dependent Kinase Inhibitor p27; 4JG2LF96VF / tuberous sclerosis complex 2 protein; EC 2.7.- / Phosphotransferases; EC 2.7.11.1 / Oncogene Protein v-akt; EC 2.7.11.1 / Ribosomal Protein S6 Kinases, 70-kDa
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78. Sugimoto Y, Araki E, Inoguchi N, Matsumura Y, Kore-eda S, Horiguchi Y, Miyachi Y, Utani A: Adult-onset multiple eccrine angiomatous hamartoma in enlarging hairy plaques. Acta Derm Venereol; 2007;87(2):180-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult-onset multiple eccrine angiomatous hamartoma in enlarging hairy plaques.
  • [MeSH-major] Eccrine Glands / pathology. Hamartoma Syndrome, Multiple / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17340034.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Norway
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79. Hellani A, Baghdadi H, Dabbour N, Almassri N, Abu-Amero KK: A novel PTCH1 germline mutation distinguishes basal cell carcinoma from basaloid follicular hamartoma: a case report. J Med Case Rep; 2009;3:52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A novel PTCH1 germline mutation distinguishes basal cell carcinoma from basaloid follicular hamartoma: a case report.
  • INTRODUCTION: Nevoid basal cell carcinoma syndrome is a rare autosomal dominant disorder characterized by numerous basal cell carcinomas, odontogenic keratocysts of the jaws and developmental defects.
  • The disorder results from mutations in the PTCH1 gene.
  • Examination of the jaw cysts revealed many keratinizing cysts without granular cell layers a finding that raised the suspicion of nevoid basal cell carcinoma.
  • These features make it difficult to differentiate between nevoid basal cell carcinoma and basaloid follicular hamartoma, especially the presence of these findings on a non-hairy area.
  • BCL-2 staining was positive in the periphery of the basaloid proliferation, which is typical of basaloid follicular hamartoma, and not in a diffuse pattern, which is typical of nevoid basal cell carcinoma.
  • Since histology was equivocal and palmoplantar pits are seen in both basaloid follicular hamartoma and nevoid basal cell carcinoma, molecular genetic investigation was necessary to differentiate between the two potential diagnoses.
  • CONCLUSION: Screening the PTCH1 gene for mutations helped to differentiate between basaloid follicular hamartoma and nevoid basal cell carcinoma and confirmed the diagnosis.

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  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2642855
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80. Kawai K: [Less invasive treatment of intractable epilepsy--vagus nerve stimulation and stereotactic radiosurgery]. Brain Nerve; 2007 Apr;59(4):299-311
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  • SRS for intractable epilepsy associated with hypothalamic hamartoma has been advocated because of a high surgical morbidity, but further study is needed for standardization of the treatment.

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  • (PMID = 17447516.001).
  • [ISSN] 1881-6096
  • [Journal-full-title] Brain and nerve = Shinkei kenkyū no shinpo
  • [ISO-abbreviation] Brain Nerve
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 81
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81. Hengstschläger M, Rosner M, Fountoulakis M, Lubec G: The cellular response to ectopic overexpression of the tuberous sclerosis genes, TSC1 and TSC2: a proteomic approach. Int J Oncol; 2005 Sep;27(3):831-8
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  • Hamartin and tuberin form a complex providing a tentative explanation for the similar disease phenotype in TSC patients with mutations in either of these genes.
  • These findings suggest that deregulation of the control of these new target proteins might contribute to the development of tubers/hamartomas in tuberous sclerosis patients.

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  • (PMID = 16077935.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Proteome; 0 / Repressor Proteins; 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; 4JG2LF96VF / tuberous sclerosis complex 2 protein
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82. Awamleh AA, Perez-Ordoñez B: Sclerosing angiomatoid nodular transformation of the spleen. Arch Pathol Lab Med; 2007 Jun;131(6):974-8
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  • The differential diagnosis of SANT includes splenic hamartoma, inflammatory myofibroblastic tumor, littoral cell angioma, and hemangioendothelioma.
  • It has been postulated that SANT represents a peculiar hamartomatous transformation of splenic red pulp in response to an exaggerated nonneoplastic stromal proliferation.
  • [MeSH-minor] Antigens, CD / metabolism. Biomarkers / metabolism. Diagnosis, Differential. Female. Hamartoma / diagnosis. Hemangioendothelioma / diagnosis. Hemangioma / diagnosis. Humans. Middle Aged. Myofibroma / diagnosis. Treatment Outcome

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  • (PMID = 17550330.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers
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83. Franz DN, Bissler JJ, McCormack FX: Tuberous sclerosis complex: neurological, renal and pulmonary manifestations. Neuropediatrics; 2010 Oct;41(5):199-208
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  • Tuberous sclerosis complex (TSC) is an important cause of epilepsy and autism, as well as renal and pulmonary disease in adults and children.
  • Affected individuals are subject to hamartomas in various organ systems which result from constitutive activation of the protein kinase mTOR (mammalian target of rapamycin).
  • The clinical course, prognosis and appropriate therapy for TSC patients are often different from that for individuals with epilepsy, renal tumors, or interstitial lung disease, from other causes.
  • This article reviews the molecular pathophysiology and management of neurological, renal and pulmonary manifestations of the disorder.


84. Mansur AT, Yasar S, Aydingöz IE, Göktay F, Ozdemir N, Sungurlu F: Colocalization of lipedematous scalp and nevus lipomatosus superficialis: a case report. J Cutan Pathol; 2007 Apr;34(4):342-5
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  • The main pathologic finding consists of increased thickness of scalp resulting from thickening of the subcutaneous fat layer.
  • Nevus lipomatosus superficialis (NLS) is an uncommon hamartomatous skin tumor characterized by soft, yellowish papules, or cerebriform plaques, usually localized on the buttock or thigh.
  • [MeSH-major] Hamartoma / complications. Scalp Dermatoses / complications. Scalp Dermatoses / pathology. Subcutaneous Fat / pathology

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  • (PMID = 17381806.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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85. Tsitouridis I, Michaelides M, Kyriakou V, Arvanity M: Endobronchial lipomatous hamartoma with mediastinal extension. J Thorac Imaging; 2010 Feb;25(1):W6-9
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  • [Title] Endobronchial lipomatous hamartoma with mediastinal extension.
  • Endobronchial hamartoma is a special form of pulmonary hamartoma.
  • We report a histologically proven case of an endobronchial lipomatous hamartoma with extrabronchial-mediastinal extension in a 64-year-old patient, and we describe the computed tomography and magnetic resonance imaging findings.
  • To our knowledge, this is the first reported case of an endobronchial hamartoma extending into the mediastinum.
  • [MeSH-major] Bronchial Neoplasms / radiography. Hamartoma / radiography. Lipoma / radiography. Mediastinum / radiography

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  • (PMID = 20160589.001).
  • [ISSN] 1536-0237
  • [Journal-full-title] Journal of thoracic imaging
  • [ISO-abbreviation] J Thorac Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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86. Lafond JF, Mulon PY, Drolet R: Fibrous vaginal hamartoma in a newborn calf. Can Vet J; 2008 Jan;49(1):61-2
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  • [Title] Fibrous vaginal hamartoma in a newborn calf.
  • A diagnosis of fibrous vaginal hamartoma was made, based on macroscopic and histologic examinations of the abnormal tissue.
  • [MeSH-major] Cattle Diseases / diagnosis. Hamartoma / veterinary. Vaginal Diseases / veterinary

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  • [Cites] J Vet Diagn Invest. 1990 Oct;2(4):338-9 [2095285.001]
  • [Cites] Vet Rec. 1990 Sep 15;127(11):279-82 [2238404.001]
  • (PMID = 18320980.001).
  • [ISSN] 0008-5286
  • [Journal-full-title] The Canadian veterinary journal = La revue vétérinaire canadienne
  • [ISO-abbreviation] Can. Vet. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2147696
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87. Xu AM, Xian ZH, Zhang SH, Chen XF: Intrahepatic cholangiocarcinoma arising in multiple bile duct hamartomas: report of two cases and review of the literature. Eur J Gastroenterol Hepatol; 2009 May;21(5):580-4
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  • [Title] Intrahepatic cholangiocarcinoma arising in multiple bile duct hamartomas: report of two cases and review of the literature.
  • Multiple bile duct hamartomas (BDHs)/von Meyenburg complexes, are tumor-like lesions of the liver.
  • Histopathologically, multiple BDHs showed morphologic transition from clearly benign to dysplasia or carcinoma in situ, then to invasive carcinoma sequence of the biliary epithelium.
  • [MeSH-major] Bile Duct Neoplasms / pathology. Bile Ducts, Intrahepatic / pathology. Cholangiocarcinoma / pathology. Hamartoma / pathology

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  • (PMID = 19282767.001).
  • [ISSN] 1473-5687
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 42
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88. Nardella D, Sohawon S, Carlier A: Lipofibromatous hamartoma of the median nerve. Three case reports. J Plast Reconstr Aesthet Surg; 2009 Sep;62(9):e314-7
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  • [Title] Lipofibromatous hamartoma of the median nerve. Three case reports.
  • Nervous lipofibromatous hamartoma is a rare tumour-like condition involving the peripheral nerves, whereby the epineurium and perineurium are enlarged and distorted by excess fatty and fibrous tissues that infiltrate between and around nerve boundaries.
  • The median nerve is much more likely than other nerves to develop a hamartoma with a predilection for the carpal tunnel.
  • In this article, we describe three cases of lipofibromatous hamartoma of the median nerve and discuss its management.
  • [MeSH-major] Hamartoma / diagnosis. Lipoma / diagnosis. Median Nerve. Median Neuropathy / diagnosis

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  • (PMID = 18485849.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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89. Thrall M, Jessurun J, Stelow EB, Adsay NV, Vickers SM, Whitson AK, Saltzman DA, Pambuccian SE: Multicystic adenomatoid hamartoma of the pancreas: a hitherto undescribed pancreatic tumor occurring in a 3-year-old boy. Pediatr Dev Pathol; 2008 Jul-Aug;11(4):314-20
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  • [Title] Multicystic adenomatoid hamartoma of the pancreas: a hitherto undescribed pancreatic tumor occurring in a 3-year-old boy.
  • As a result of its superficial resemblance to Stocker type 2 cystic adenomatoid malformation of the lung, we are proposing the name "multicystic adenomatoid hamartoma" for this lesion.
  • [MeSH-major] Hamartoma / pathology. Pancreatic Diseases / pathology
  • [MeSH-minor] Biomarkers / metabolism. Cell Proliferation. Child, Preschool. Disease-Free Survival. Humans. Immunoenzyme Techniques. Keratin-7 / metabolism. Magnetic Resonance Imaging. Male. Pancreas / metabolism. Pancreas / pathology. Pancreaticoduodenectomy

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  • (PMID = 17990924.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Keratin-7
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90. Chand G, Chowdhury V, Singh S: Median nerve hamartoma: Findings on magnetic resonance imaging. Ann Indian Acad Neurol; 2008 Oct;11(4):259-60
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  • [Title] Median nerve hamartoma: Findings on magnetic resonance imaging.

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  • [Cites] Skeletal Radiol. 1999 May;28(5):260-4 [10424331.001]
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  • (PMID = 19893687.001).
  • [ISSN] 1998-3549
  • [Journal-full-title] Annals of Indian Academy of Neurology
  • [ISO-abbreviation] Ann Indian Acad Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2771984
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91. Ding HJ, Wu QS, Dong YG, Hu YY, Chen JM: [Fibroleiomyomatous hamartomas of lung: report of a case]. Zhonghua Bing Li Xue Za Zhi; 2008 Aug;37(8):570-1
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  • [Title] [Fibroleiomyomatous hamartomas of lung: report of a case].
  • [MeSH-major] Hamartoma / pathology. Lung / pathology. Lung Neoplasms / pathology

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  • (PMID = 19094476.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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92. Mennel S, Hausmann N, Meyer CH, Peter S: Photodynamic therapy for exudative hamartoma in tuberous sclerosis. Arch Ophthalmol; 2006 Apr;124(4):597-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Photodynamic therapy for exudative hamartoma in tuberous sclerosis.
  • [MeSH-major] Hamartoma / drug therapy. Photochemotherapy. Retinal Diseases / drug therapy. Tuberous Sclerosis / drug therapy

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  • (PMID = 16606894.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Porphyrins; 129497-78-5 / verteporfin
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93. Curatolo P, Bombardieri R, Jozwiak S: Tuberous sclerosis. Lancet; 2008 Aug 23;372(9639):657-68
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  • Tuberous sclerosis is a genetic multisystem disorder characterised by widespread hamartomas in several organs, including the brain, heart, skin, eyes, kidney, lung, and liver.
  • Increasing understanding of the molecular abnormalities caused by tuberous sclerosis may enable improved management of this disease.


94. Oakley GJ 3rd, Schraut WH, Peel R, Krasinskas A: Diffuse filiform polyposis with unique histology mimicking familial adenomatous polyposis in a patient without inflammatory bowel disease. Arch Pathol Lab Med; 2007 Dec;131(12):1821-4
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  • [Title] Diffuse filiform polyposis with unique histology mimicking familial adenomatous polyposis in a patient without inflammatory bowel disease.
  • Filiform polyposis is an uncommon entity that is most often encountered in the colon of patients with a history of inflammatory bowel disease (IBD).
  • Neuromuscular and vascular hamartoma of the small bowel is a rare, focal disorder characterized by disorganized smooth muscle fascicles throughout the submucosa accompanied by fibrosis, nerve fibers, ganglion cells, and vessels.
  • Here we report the case of a 50-year-old man with no known history or symptoms of IBD presenting with filiform polyposis involving the entire colon, clinically mimicking familial adenomatous polyposis, and showing histologic features similar to neuromuscular and vascular hamartoma of the small bowel.

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  • (PMID = 18081442.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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95. Sammarco G, Filiotis N, Triggiani D, Teodossiu G, Cuccia F, Lazzaro R, Marra E, Triggiani E: Brunner's gland hamartoma: a case report and review of literature. Ann Ital Chir; 2008 Mar-Apr;79(2):139-42
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  • [Title] Brunner's gland hamartoma: a case report and review of literature.
  • BACKGROUND: Brunner's hamartoma is a quite rare neoformation whose origin is not completely clear.
  • METHODS: A case of a 69-year-old man with recurrent epigastric pain and an endoscopic finding of a duodenal mass is reported.
  • RESULTS: The complete removal of hamartoma can give a complete remission of symptoms.
  • CONCLUSIONS: Hamartoma can be only diagnosed by endoscopy and histological exam; its therapy is always surgical, also in order to avoid possible malignant degeneration.
  • [MeSH-major] Brunner Glands. Duodenal Neoplasms. Hamartoma

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  • (PMID = 18727278.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Italy
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96. Małgorzata S, Maria KK, Jan K: [Pulmonary disease in patients with tuberous sclerosis]. Pneumonol Alergol Pol; 2005;73(1):48-56
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  • [Title] [Pulmonary disease in patients with tuberous sclerosis].
  • Tuberous sclerosis (TSC) is an autosomal dominant disorder with the incidence of 1/10 000.
  • The disease is characterized by epilepsy, mental retardation, the occurrence of hamartomas in the various organs and angiomyolipomas in the kidney.


97. Lok C, Viseux V, Avril MF, Richard MA, Gondry-Jouet C, Deramond H, Desfossez-Tribout C, Courtade S, Delaunay M, Piette F, Legars D, Dreno B, Saïag P, Longy M, Lorette G, Laroche L, Caux F, Cancerology Group of the French Society of Dermatology: Brain magnetic resonance imaging in patients with Cowden syndrome. Medicine (Baltimore); 2005 Mar;84(2):129-36
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  • Cowden syndrome (CS) is a rare autosomal dominant genodermatosis, characterized by multiple hamartomas, particularly of the skin, associated with high frequencies of breast, thyroid, and genitourinary malignancies.
  • Although Lhermitte-Duclos disease (LDD) or dysplastic gangliocytoma of the cerebellum, a slowly progressive unilateral tumor, is a major criterion of CS, its frequency in patients with CS is unknown.
  • Because CS signs can involve numerous systems, all physicians who might encounter this disease should be aware of its neurologic manifestations.
  • [MeSH-major] Brain / pathology. Hamartoma Syndrome, Multiple / pathology. Magnetic Resonance Imaging

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  • (PMID = 15758842.001).
  • [ISSN] 0025-7974
  • [Journal-full-title] Medicine
  • [ISO-abbreviation] Medicine (Baltimore)
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; EC 3.1.3.- / Phosphoric Monoester Hydrolases; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
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98. Park KY, Kim SJ, Noh TW, Cho SH, Lee DY, Paik HC, Ryu YH: Diagnostic efficacy and characteristic feature of MRI in pulmonary hamartoma: comparison with CT, specimen MRI, and pathology. J Comput Assist Tomogr; 2008 Nov-Dec;32(6):919-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic efficacy and characteristic feature of MRI in pulmonary hamartoma: comparison with CT, specimen MRI, and pathology.
  • OBJECTIVES: To determine the diagnostic efficacy of magnetic resonance imaging (MRI) in pulmonary hamartoma and observe the significant MRI features, other than fat or characteristic calcification revealed by computed tomography (CT).
  • METHODS: Six hamartomas were included and surgically resected, and we prospectively studied MRI in cases showing suggestive findings of hamartoma or indeterminate nodule on CT.
  • RESULTS: Computed tomography revealed suggestive findings of pulmonary hamartoma (fat or popcorn calcification) in only 3.
  • All MRI revealed cleftlike structures particularly evident on T2-weighted images with same detectability as its specimen MRI: peripheral linear or curvilinear inclusions with sometimes intratumoral cleftlike space (n = 3), variable signal intensity, and frequent enhancement (3 in 4) pathologically correlated with the variable mesenchymal tissue components and amount arrayed along respiratory epithelial cells lining the cleft and richer vascularity than main portion of pulmonary hamartoma.
  • CONCLUSIONS: Magnetic resonance imaging study is a useful diagnostic tool, when a discrete pulmonary nodule demonstrates neither fat nor calcification on CT, for detecting the quite typical cleftlike structure in a pulmonary hamartoma and could provide diagnostic confidence.
  • [MeSH-major] Calcinosis / radiography. Hamartoma / diagnosis. Image Interpretation, Computer-Assisted / methods. Lung Diseases / diagnosis. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 19204455.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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99. Alexander MP, Makhija P, Jayaseelan E: Fine needle aspiration cytology of trichofolliculoma: a case report. Indian J Pathol Microbiol; 2007 Oct;50(4):870-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report the first case of trichofolliculoma, a hair follicle hamartoma, which was subsequently diagnosed by excision biopsy.
  • The finding of cohesive, branching keratinized squamous cell clusters admixed with sebaceous cells may suggest a diagnosis of trichofolliculoma, as was seen in the present case.
  • [MeSH-major] Hair Follicle / pathology. Hamartoma / diagnosis. Hamartoma / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Trichofolliculoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
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  • (PMID = 18306593.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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100. Sánchez-López M, Martínez-Fernández R, Santamaría-Carro A: [Ocular manifestations in Proteus syndrome]. Arch Soc Esp Oftalmol; 2007 Mar;82(3):175-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • DISCUSSION: Proteus syndrome is a complex hamartomatous disorder defined by local overgrowth, subcutaneous tumours and various bone, cutaneous and/or vascular anomalies.

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  • (PMID = 17357896.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Retinal Pigments
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