[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Item 1 of about 1
1. Alsousou J, Thompson M, Hulley P, Noble A, Willett K: The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: a review of the literature. J Bone Joint Surg Br; 2009 Aug;91(8):987-96
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: a review of the literature.
  • Although mechanical stabilisation has been a hallmark of orthopaedic surgical management, orthobiologics are now playing an increasing role.
  • Platelet-rich plasma (PRP) is a volume of plasma fraction of autologous blood having platelet concentrations above baseline.
  • The platelet alpha granules are rich in growth factors that play an essential role in tissue healing, such as transforming growth factor-beta, vascular endothelial growth factor, and platelet-derived growth factor.
  • PRP is used in various surgical fields to enhance bone and soft-tissue healing by placing supraphysiological concentrations of autologous platelets at the site of tissue damage.
  • The easily obtainable PRP and its possible beneficial outcome hold promise for new regenerative treatment approaches.
  • The aim of this literature review was to describe the bioactivities of PRP, to elucidate the different techniques for PRP preparation, to review animal and human studies, to evaluate the evidence regarding the use of PRP in trauma and orthopaedic surgery, to clarify risks, and to provide guidance for future research.
  • [MeSH-major] Fracture Healing / physiology. Intercellular Signaling Peptides and Proteins / therapeutic use. Platelet-Rich Plasma / physiology. Wounds and Injuries / therapy
  • [MeSH-minor] Animals. Female. Humans. Male. Orthopedic Procedures. Specimen Handling / methods

  • MedlinePlus Health Information. consumer health - Wounds and Injuries.
  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19651823.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Intercellular Signaling Peptides and Proteins
  • [Number-of-references] 101
  •  go-up   go-down


Advertisement





Advertisement