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1. Hall MP, Band PA, Meislin RJ, Jazrawi LM, Cardone DA: Platelet-rich plasma: current concepts and application in sports medicine. J Am Acad Orthop Surg; 2009 Oct;17(10):602-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Platelet-rich plasma: current concepts and application in sports medicine.
  • Platelet-rich plasma is defined as autologous blood with a concentration of platelets above baseline values.
  • Platelet-rich plasma has been used in maxillofacial and plastic surgery since the 1990s; its use in sports medicine is growing given its potential to enhance muscle and tendon healing.
  • In vitro studies suggest that growth factors released by platelets recruit reparative cells and may augment soft-tissue repair.
  • Although minimal clinical evidence is currently available, the use of platelet-rich plasma has increased, given its safety as well as the availability of new devices for outpatient preparation and delivery.
  • Its use in surgery to augment rotator cuff and Achilles tendon repair has also been reported.
  • As the marketing of platelet-rich plasma increases, orthopaedic surgeons must be informed regarding the available preparation devices and their differences.
  • Many controlled clinical trials are under way, but clinical use should be approached cautiously until high-level clinical evidence supporting platelet-rich plasma efficacy is available.
  • [MeSH-major] Musculoskeletal System / injuries. Platelet-Rich Plasma. Wound Healing
  • [MeSH-minor] Achilles Tendon / injuries. Achilles Tendon / surgery. Anterior Cruciate Ligament / injuries. Anterior Cruciate Ligament / surgery. Humans. Orthopedics / trends. Rotator Cuff / injuries. Rotator Cuff / surgery. Sports Medicine / trends. Tendon Injuries / surgery. Tennis Elbow / therapy. Therapies, Investigational

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  • [ErratumIn] J Am Acad Orthop Surg. 2010 Jan;18(1):17A
  • (PMID = 19794217.001).
  • [ISSN] 1067-151X
  • [Journal-full-title] The Journal of the American Academy of Orthopaedic Surgeons
  • [ISO-abbreviation] J Am Acad Orthop Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
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